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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ANLN-SEPT7 (FusionGDB2 ID:HG54443TG989)

Fusion Gene Summary for ANLN-SEPT7

check button Fusion gene summary
Fusion gene informationFusion gene name: ANLN-SEPT7
Fusion gene ID: hg54443tg989
HgeneTgene
Gene symbol

ANLN

SEPT7

Gene ID

54443

989

Gene nameanillin actin binding proteinseptin 7
SynonymsFSGS8|Scraps|scraCDC10|CDC3|NBLA02942|SEPT7|SEPT7A
Cytomap('ANLN')('SEPT7')

7p14.2

7p14.2

Type of geneprotein-codingprotein-coding
Descriptionanillinseptin-7CDC10 (cell division cycle 10, S. cerevisiae, homolog)CDC10 protein homologseptin 7 variant 4
Modification date2020031320200313
UniProtAcc

Q9NQW6

.
Ensembl transtripts involved in fusion geneENST00000265748, ENST00000396068, 
ENST00000495714, 
Fusion gene scores* DoF score6 X 8 X 7=3364 X 3 X 4=48
# samples 104
** MAII scorelog2(10/336*10)=-1.74846123300404
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/48*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ANLN [Title/Abstract] AND SEPT7 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointANLN(36439002)-SEPT7(35903162), # samples:1
Anticipated loss of major functional domain due to fusion event.ANLN-SEPT7 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ANLN-SEPT7 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ANLN-SEPT7 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ANLN-SEPT7 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneANLN

GO:0000281

mitotic cytokinesis

10931866

TgeneSEPT7

GO:0030336

negative regulation of cell migration

-

TgeneSEPT7

GO:0043065

positive regulation of apoptotic process

-

TgeneSEPT7

GO:2000134

negative regulation of G1/S transition of mitotic cell cycle

-


check buttonFusion gene breakpoints across ANLN (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across SEPT7 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ESCATCGA-L5-A891ANLNchr7

36439002

+SEPT7chr7

35903162

+


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Fusion Gene ORF analysis for ANLN-SEPT7

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000265748ENST00000475109ANLNchr7

36439002

+SEPT7chr7

35903162

+
5CDS-3UTRENST00000265748ENST00000494488ANLNchr7

36439002

+SEPT7chr7

35903162

+
5CDS-3UTRENST00000396068ENST00000475109ANLNchr7

36439002

+SEPT7chr7

35903162

+
5CDS-3UTRENST00000396068ENST00000494488ANLNchr7

36439002

+SEPT7chr7

35903162

+
5CDS-intronENST00000265748ENST00000432293ANLNchr7

36439002

+SEPT7chr7

35903162

+
5CDS-intronENST00000396068ENST00000432293ANLNchr7

36439002

+SEPT7chr7

35903162

+
In-frameENST00000265748ENST00000350320ANLNchr7

36439002

+SEPT7chr7

35903162

+
In-frameENST00000265748ENST00000399034ANLNchr7

36439002

+SEPT7chr7

35903162

+
In-frameENST00000265748ENST00000399035ANLNchr7

36439002

+SEPT7chr7

35903162

+
In-frameENST00000265748ENST00000435235ANLNchr7

36439002

+SEPT7chr7

35903162

+
In-frameENST00000265748ENST00000469679ANLNchr7

36439002

+SEPT7chr7

35903162

+
In-frameENST00000396068ENST00000350320ANLNchr7

36439002

+SEPT7chr7

35903162

+
In-frameENST00000396068ENST00000399034ANLNchr7

36439002

+SEPT7chr7

35903162

+
In-frameENST00000396068ENST00000399035ANLNchr7

36439002

+SEPT7chr7

35903162

+
In-frameENST00000396068ENST00000435235ANLNchr7

36439002

+SEPT7chr7

35903162

+
In-frameENST00000396068ENST00000469679ANLNchr7

36439002

+SEPT7chr7

35903162

+
intron-3CDSENST00000495714ENST00000350320ANLNchr7

36439002

+SEPT7chr7

35903162

+
intron-3CDSENST00000495714ENST00000399034ANLNchr7

36439002

+SEPT7chr7

35903162

+
intron-3CDSENST00000495714ENST00000399035ANLNchr7

36439002

+SEPT7chr7

35903162

+
intron-3CDSENST00000495714ENST00000435235ANLNchr7

36439002

+SEPT7chr7

35903162

+
intron-3CDSENST00000495714ENST00000469679ANLNchr7

36439002

+SEPT7chr7

35903162

+
intron-3UTRENST00000495714ENST00000475109ANLNchr7

36439002

+SEPT7chr7

35903162

+
intron-3UTRENST00000495714ENST00000494488ANLNchr7

36439002

+SEPT7chr7

35903162

+
intron-intronENST00000495714ENST00000432293ANLNchr7

36439002

+SEPT7chr7

35903162

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000265748ANLNchr736439002+ENST00000435235SEPT7chr735903162+28677082211852543
ENST00000265748ANLNchr736439002+ENST00000469679SEPT7chr735903162+12477082211246342
ENST00000265748ANLNchr736439002+ENST00000399034SEPT7chr735903162+28657082211852543
ENST00000265748ANLNchr736439002+ENST00000350320SEPT7chr735903162+28657082211852543
ENST00000265748ANLNchr736439002+ENST00000399035SEPT7chr735903162+28657082211852543
ENST00000396068ANLNchr736439002+ENST00000435235SEPT7chr735903162+28526932061837543
ENST00000396068ANLNchr736439002+ENST00000469679SEPT7chr735903162+12326932061231342
ENST00000396068ANLNchr736439002+ENST00000399034SEPT7chr735903162+28506932061837543
ENST00000396068ANLNchr736439002+ENST00000350320SEPT7chr735903162+28506932061837543
ENST00000396068ANLNchr736439002+ENST00000399035SEPT7chr735903162+28506932061837543

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000265748ENST00000435235ANLNchr736439002+SEPT7chr735903162+0.0003910440.99960893
ENST00000265748ENST00000469679ANLNchr736439002+SEPT7chr735903162+0.454242050.5457579
ENST00000265748ENST00000399034ANLNchr736439002+SEPT7chr735903162+0.0003962570.9996038
ENST00000265748ENST00000350320ANLNchr736439002+SEPT7chr735903162+0.0003962570.9996038
ENST00000265748ENST00000399035ANLNchr736439002+SEPT7chr735903162+0.0003962570.9996038
ENST00000396068ENST00000435235ANLNchr736439002+SEPT7chr735903162+0.0003881130.9996119
ENST00000396068ENST00000469679ANLNchr736439002+SEPT7chr735903162+0.46417390.5358261
ENST00000396068ENST00000399034ANLNchr736439002+SEPT7chr735903162+0.0003932690.9996068
ENST00000396068ENST00000350320ANLNchr736439002+SEPT7chr735903162+0.0003932690.9996068
ENST00000396068ENST00000399035ANLNchr736439002+SEPT7chr735903162+0.0003932690.9996068

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Fusion Genomic Features for ANLN-SEPT7


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ANLNchr736439002+SEPT7chr735903161+0.0214769580.9785231
ANLNchr736439002+SEPT7chr735903161+0.0214769580.9785231

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ANLN-SEPT7


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:36439002/chr7:35903162)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ANLN

Q9NQW6

.
FUNCTION: Required for cytokinesis (PubMed:16040610). Essential for the structural integrity of the cleavage furrow and for completion of cleavage furrow ingression. Plays a role in bleb assembly during metaphase and anaphase of mitosis (PubMed:23870127). May play a significant role in podocyte cell migration (PubMed:24676636). {ECO:0000269|PubMed:10931866, ECO:0000269|PubMed:12479805, ECO:0000269|PubMed:15496454, ECO:0000269|PubMed:16040610, ECO:0000269|PubMed:16357138, ECO:0000269|PubMed:23870127, ECO:0000269|PubMed:24676636}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneANLNchr7:36439002chr7:35903162ENST00000265748+3241_451621125.0RegionNote=Required for ubiquitination
HgeneANLNchr7:36439002chr7:35903162ENST00000396068+3231_451621088.0RegionNote=Required for ubiquitination
TgeneSEPT7chr7:36439002chr7:35903162ENST00000399034214332_43757439.0Coiled coilOntology_term=ECO:0000255
TgeneSEPT7chr7:36439002chr7:35903162ENST00000399034214195_20357439.0Nucleotide bindingGTP
TgeneSEPT7chr7:36439002chr7:35903162ENST00000399034214113_11657439.0RegionG3 motif
TgeneSEPT7chr7:36439002chr7:35903162ENST00000399034214194_19757439.0RegionG4 motif
TgeneSEPT7chr7:36439002chr7:35903162ENST0000039903421457_6457439.0RegionG1 motif

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneANLNchr7:36439002chr7:35903162ENST00000265748+324569_6041621125.0Coiled coilOntology_term=ECO:0000255
HgeneANLNchr7:36439002chr7:35903162ENST00000396068+323569_6041621088.0Coiled coilOntology_term=ECO:0000255
HgeneANLNchr7:36439002chr7:35903162ENST00000265748+324983_11071621125.0DomainPH
HgeneANLNchr7:36439002chr7:35903162ENST00000396068+323983_11071621088.0DomainPH
HgeneANLNchr7:36439002chr7:35903162ENST00000265748+3241_2301621125.0RegionNote=Nuclear localization
HgeneANLNchr7:36439002chr7:35903162ENST00000265748+324730_11241621125.0RegionNote=Localization to the cleavage furrow
HgeneANLNchr7:36439002chr7:35903162ENST00000396068+3231_2301621088.0RegionNote=Nuclear localization
HgeneANLNchr7:36439002chr7:35903162ENST00000396068+323730_11241621088.0RegionNote=Localization to the cleavage furrow
TgeneSEPT7chr7:36439002chr7:35903162ENST0000039903421447_31657439.0DomainSeptin-type G


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Fusion Gene Sequence for ANLN-SEPT7


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>4835_4835_1_ANLN-SEPT7_ANLN_chr7_36439002_ENST00000265748_SEPT7_chr7_35903162_ENST00000350320_length(transcript)=2865nt_BP=708nt
AGCGCGCATGCTCGCGGCTCGGCGCTGAAATTCAAATTTGAACGGCTGCAGAGGCCGAGTCCGTCACTGGAAGCCGAGAGGAGAGGACAG
CTGGTTGTGGGAGAGTTCCCCCGCCTCAGACTCCTGGTTTTTTCCAGGAGACACACTGAGCTGAGACTCACTTTTCTCTTCCTGAATTTG
AACCACCGTTTCCATCGTCTCGTAGTCCGACGCCTGGGGCGATGGATCCGTTTACGGAGAAACTGCTGGAGCGAACCCGTGCCAGGCGAG
AGAATCTTCAGAGAAAAATGGCTGAGAGGCCCACAGCAGCTCCAAGGTCTATGACTCATGCTAAGCGAGCTAGACAGCCACTTTCAGAAG
CAAGTAACCAGCAGCCCCTCTCTGGTGGTGAAGAGAAATCTTGTACAAAACCATCGCCATCAAAAAAACGCTGTTCTGACAACACTGAAG
TAGAAGTTTCTAACTTGGAAAATAAACAACCAGTTGAGTCGACATCTGCAAAATCTTGTTCTCCAAGTCCTGTGTCTCCTCAGGTGCAGC
CACAAGCAGCAGATACCATCAGTGATTCTGTTGCTGTCCCGGCATCACTGCTGGGCATGAGGAGAGGGCTGAACTCAAGATTGGAAGCAA
CTGCAGCCTCCTCAGTTAAAACACGTATGCAAAAACTTGCAGAGCAACGGCGCCGTTGGGATAATGATGATATGACAGGTGAATCTGGAT
TGGGAAAGTCGACATTAATCAACTCATTATTCCTCACAGATTTGTATTCTCCAGAGTATCCAGGTCCTTCTCATAGAATTAAAAAGACTG
TACAGGTGGAACAATCCAAAGTTTTAATCAAAGAAGGTGGTGTTCAGTTGCTGCTCACAATAGTTGATACCCCAGGATTTGGAGATGCAG
TGGATAATAGTAATTGCTGGCAGCCTGTTATCGACTACATTGATAGTAAATTTGAGGACTACCTAAATGCAGAATCACGAGTGAACAGAC
GTCAGATGCCTGATAACAGGGTGCAGTGTTGTTTATACTTCATTGCTCCTTCAGGACATGGACTTAAACCATTGGATATTGAGTTTATGA
AGCGTTTGCATGAAAAAGTGAATATCATCCCACTTATTGCCAAAGCAGACACACTCACACCAGAGGAATGCCAACAGTTTAAAAAACAGA
TAATGAAAGAAATCCAAGAACATAAAATTAAAATATACGAATTTCCAGAAACAGATGATGAAGAAGAAAATAAACTTGTTAAAAAGATAA
AGGACCGTTTACCTCTTGCTGTGGTAGGTAGTAATACTATCATTGAAGTTAATGGCAAAAGGGTCAGAGGAAGGCAGTATCCTTGGGGTG
TTGCTGAAGTTGAAAATGGTGAACATTGTGATTTTACAATCCTAAGAAATATGTTGATAAGAACACACATGCAGGACTTGAAAGATGTTA
CTAATAATGTCCACTATGAGAACTACAGAAGCAGAAAACTTGCAGCTGTGACTTATAATGGAGTTGATAACAACAAGAATAAAGGGCAGC
TGACTAAGAGCCCTCTGGCACAAATGGAAGAAGAAAGAAGGGAGCATGTAGCTAAAATGAAGAAGATGGAGATGGAGATGGAGCAGGTGT
TTGAGATGAAGGTCAAAGAAAAAGTTCAAAAACTGAAGGACTCTGAAGCTGAGCTCCAGCGGCGCCATGAGCAAATGAAAAAGAATTTGG
AAGCACAGCACAAAGAATTGGAGGAAAAACGTCGTCAGTTCGAGGATGAGAAAGCAAACTGGGAAGCTCAACAACGTATTTTAGAACAAC
AGAACTCTTCAAGAACCTTGGAAAAGAACAAGAAGAAAGGGAAGATCTTTTAAACTCTCTATTGACCACCAGTTAACGTATTAGTTGCCA
ATATGCCAGCTTGGACATCAGTGTTTGTTGGATCCGTTTGACCAATTTGCACCAGTTTTATCCATAATGATGGATTTAACAGCATGACAA
AAATTATTTTTTTTTTTGTTCTTGATGGAGATTAAGATGCCTTGAATTGTCTAGGGTGTTCTGTACTTAGAAAGTAAGAGCTCTAAGTAC
CTTTCCTACATTTTCTTTTTTTATTAAACAGATATCTTCAGTTTAATGCAAGAGAACATTTTACTGTTGTACAATCATGTTCTGGTGGTT
TGATTGTTTACAGGATATTCCAAAATAAAAGGACTCTGGAAGATTTTCATTGAGGATAAATTGCCATAATATGATGCAAACTGTGCTTCT
CTATGATAATTACAATACAAAGGTTCCATTCAGTGCAGCATATACAATAATGTAATTTAGTCTAACACAGTTGACCCTATTTTTTGACAC
TTCCATTGTTTAAAAATACACATGGAAAAAAAAAAAACCCTATATGCTTACTGTGCACCTAGAGCTTTTTTATAACAACGTCTTTTTGTT
TGTTTGTTTTGGATTCTTTAAATATATATTATTCTCATTTAGTGCCCTCTTTAGCCAGAATCTCATTACTGCTTCATTTTTGTAATAACA
TTTAATTTAGATATTTTCCATATATTGGCACTGCTAAAATAGAATATAGCATCTTTCATATGGTAGGAACCAACAAGGAAACTTTCCTTT
AACTCCCTTTTTACACTTTATGGTAAGTAGCAGGGGGGGAAATGCATTTATAGATCATTTCTAGGCAAAATTGTGAAGCTAATGACCAAC
CTGTTTCTACCTATATGCAGTCTCTTTATTTTACTAGAAATGGGAATCATGGCCTCTTGAAGAGAAAAAAGTCACCATTCTGCATTTAGC

>4835_4835_1_ANLN-SEPT7_ANLN_chr7_36439002_ENST00000265748_SEPT7_chr7_35903162_ENST00000350320_length(amino acids)=543AA_BP=162
MDPFTEKLLERTRARRENLQRKMAERPTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKSCTKPSPSKKRCSDNTEVEVSNLENKQPVES
TSAKSCSPSPVSPQVQPQAADTISDSVAVPASLLGMRRGLNSRLEATAASSVKTRMQKLAEQRRRWDNDDMTGESGLGKSTLINSLFLTD
LYSPEYPGPSHRIKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESRVNRRQMPDNRVQCCLYF
IAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFKKQIMKEIQEHKIKIYEFPETDDEEENKLVKKIKDRLPLAVVGSNTI
IEVNGKRVRGRQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDNNKNKGQLTKSPLAQMEEERR
EHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHEQMKKNLEAQHKELEEKRRQFEDEKANWEAQQRILEQQNSSRTLEKNKKKG

--------------------------------------------------------------
>4835_4835_2_ANLN-SEPT7_ANLN_chr7_36439002_ENST00000265748_SEPT7_chr7_35903162_ENST00000399034_length(transcript)=2865nt_BP=708nt
AGCGCGCATGCTCGCGGCTCGGCGCTGAAATTCAAATTTGAACGGCTGCAGAGGCCGAGTCCGTCACTGGAAGCCGAGAGGAGAGGACAG
CTGGTTGTGGGAGAGTTCCCCCGCCTCAGACTCCTGGTTTTTTCCAGGAGACACACTGAGCTGAGACTCACTTTTCTCTTCCTGAATTTG
AACCACCGTTTCCATCGTCTCGTAGTCCGACGCCTGGGGCGATGGATCCGTTTACGGAGAAACTGCTGGAGCGAACCCGTGCCAGGCGAG
AGAATCTTCAGAGAAAAATGGCTGAGAGGCCCACAGCAGCTCCAAGGTCTATGACTCATGCTAAGCGAGCTAGACAGCCACTTTCAGAAG
CAAGTAACCAGCAGCCCCTCTCTGGTGGTGAAGAGAAATCTTGTACAAAACCATCGCCATCAAAAAAACGCTGTTCTGACAACACTGAAG
TAGAAGTTTCTAACTTGGAAAATAAACAACCAGTTGAGTCGACATCTGCAAAATCTTGTTCTCCAAGTCCTGTGTCTCCTCAGGTGCAGC
CACAAGCAGCAGATACCATCAGTGATTCTGTTGCTGTCCCGGCATCACTGCTGGGCATGAGGAGAGGGCTGAACTCAAGATTGGAAGCAA
CTGCAGCCTCCTCAGTTAAAACACGTATGCAAAAACTTGCAGAGCAACGGCGCCGTTGGGATAATGATGATATGACAGGTGAATCTGGAT
TGGGAAAGTCGACATTAATCAACTCATTATTCCTCACAGATTTGTATTCTCCAGAGTATCCAGGTCCTTCTCATAGAATTAAAAAGACTG
TACAGGTGGAACAATCCAAAGTTTTAATCAAAGAAGGTGGTGTTCAGTTGCTGCTCACAATAGTTGATACCCCAGGATTTGGAGATGCAG
TGGATAATAGTAATTGCTGGCAGCCTGTTATCGACTACATTGATAGTAAATTTGAGGACTACCTAAATGCAGAATCACGAGTGAACAGAC
GTCAGATGCCTGATAACAGGGTGCAGTGTTGTTTATACTTCATTGCTCCTTCAGGACATGGACTTAAACCATTGGATATTGAGTTTATGA
AGCGTTTGCATGAAAAAGTGAATATCATCCCACTTATTGCCAAAGCAGACACACTCACACCAGAGGAATGCCAACAGTTTAAAAAACAGA
TAATGAAAGAAATCCAAGAACATAAAATTAAAATATACGAATTTCCAGAAACAGATGATGAAGAAGAAAATAAACTTGTTAAAAAGATAA
AGGACCGTTTACCTCTTGCTGTGGTAGGTAGTAATACTATCATTGAAGTTAATGGCAAAAGGGTCAGAGGAAGGCAGTATCCTTGGGGTG
TTGCTGAAGTTGAAAATGGTGAACATTGTGATTTTACAATCCTAAGAAATATGTTGATAAGAACACACATGCAGGACTTGAAAGATGTTA
CTAATAATGTCCACTATGAGAACTACAGAAGCAGAAAACTTGCAGCTGTGACTTATAATGGAGTTGATAACAACAAGAATAAAGGGCAGC
TGACTAAGAGCCCTCTGGCACAAATGGAAGAAGAAAGAAGGGAGCATGTAGCTAAAATGAAGAAGATGGAGATGGAGATGGAGCAGGTGT
TTGAGATGAAGGTCAAAGAAAAAGTTCAAAAACTGAAGGACTCTGAAGCTGAGCTCCAGCGGCGCCATGAGCAAATGAAAAAGAATTTGG
AAGCACAGCACAAAGAATTGGAGGAAAAACGTCGTCAGTTCGAGGATGAGAAAGCAAACTGGGAAGCTCAACAACGTATTTTAGAACAAC
AGAACTCTTCAAGAACCTTGGAAAAGAACAAGAAGAAAGGGAAGATCTTTTAAACTCTCTATTGACCACCAGTTAACGTATTAGTTGCCA
ATATGCCAGCTTGGACATCAGTGTTTGTTGGATCCGTTTGACCAATTTGCACCAGTTTTATCCATAATGATGGATTTAACAGCATGACAA
AAATTATTTTTTTTTTTGTTCTTGATGGAGATTAAGATGCCTTGAATTGTCTAGGGTGTTCTGTACTTAGAAAGTAAGAGCTCTAAGTAC
CTTTCCTACATTTTCTTTTTTTATTAAACAGATATCTTCAGTTTAATGCAAGAGAACATTTTACTGTTGTACAATCATGTTCTGGTGGTT
TGATTGTTTACAGGATATTCCAAAATAAAAGGACTCTGGAAGATTTTCATTGAGGATAAATTGCCATAATATGATGCAAACTGTGCTTCT
CTATGATAATTACAATACAAAGGTTCCATTCAGTGCAGCATATACAATAATGTAATTTAGTCTAACACAGTTGACCCTATTTTTTGACAC
TTCCATTGTTTAAAAATACACATGGAAAAAAAAAAAACCCTATATGCTTACTGTGCACCTAGAGCTTTTTTATAACAACGTCTTTTTGTT
TGTTTGTTTTGGATTCTTTAAATATATATTATTCTCATTTAGTGCCCTCTTTAGCCAGAATCTCATTACTGCTTCATTTTTGTAATAACA
TTTAATTTAGATATTTTCCATATATTGGCACTGCTAAAATAGAATATAGCATCTTTCATATGGTAGGAACCAACAAGGAAACTTTCCTTT
AACTCCCTTTTTACACTTTATGGTAAGTAGCAGGGGGGGAAATGCATTTATAGATCATTTCTAGGCAAAATTGTGAAGCTAATGACCAAC
CTGTTTCTACCTATATGCAGTCTCTTTATTTTACTAGAAATGGGAATCATGGCCTCTTGAAGAGAAAAAAGTCACCATTCTGCATTTAGC

>4835_4835_2_ANLN-SEPT7_ANLN_chr7_36439002_ENST00000265748_SEPT7_chr7_35903162_ENST00000399034_length(amino acids)=543AA_BP=162
MDPFTEKLLERTRARRENLQRKMAERPTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKSCTKPSPSKKRCSDNTEVEVSNLENKQPVES
TSAKSCSPSPVSPQVQPQAADTISDSVAVPASLLGMRRGLNSRLEATAASSVKTRMQKLAEQRRRWDNDDMTGESGLGKSTLINSLFLTD
LYSPEYPGPSHRIKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESRVNRRQMPDNRVQCCLYF
IAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFKKQIMKEIQEHKIKIYEFPETDDEEENKLVKKIKDRLPLAVVGSNTI
IEVNGKRVRGRQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDNNKNKGQLTKSPLAQMEEERR
EHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHEQMKKNLEAQHKELEEKRRQFEDEKANWEAQQRILEQQNSSRTLEKNKKKG

--------------------------------------------------------------
>4835_4835_3_ANLN-SEPT7_ANLN_chr7_36439002_ENST00000265748_SEPT7_chr7_35903162_ENST00000399035_length(transcript)=2865nt_BP=708nt
AGCGCGCATGCTCGCGGCTCGGCGCTGAAATTCAAATTTGAACGGCTGCAGAGGCCGAGTCCGTCACTGGAAGCCGAGAGGAGAGGACAG
CTGGTTGTGGGAGAGTTCCCCCGCCTCAGACTCCTGGTTTTTTCCAGGAGACACACTGAGCTGAGACTCACTTTTCTCTTCCTGAATTTG
AACCACCGTTTCCATCGTCTCGTAGTCCGACGCCTGGGGCGATGGATCCGTTTACGGAGAAACTGCTGGAGCGAACCCGTGCCAGGCGAG
AGAATCTTCAGAGAAAAATGGCTGAGAGGCCCACAGCAGCTCCAAGGTCTATGACTCATGCTAAGCGAGCTAGACAGCCACTTTCAGAAG
CAAGTAACCAGCAGCCCCTCTCTGGTGGTGAAGAGAAATCTTGTACAAAACCATCGCCATCAAAAAAACGCTGTTCTGACAACACTGAAG
TAGAAGTTTCTAACTTGGAAAATAAACAACCAGTTGAGTCGACATCTGCAAAATCTTGTTCTCCAAGTCCTGTGTCTCCTCAGGTGCAGC
CACAAGCAGCAGATACCATCAGTGATTCTGTTGCTGTCCCGGCATCACTGCTGGGCATGAGGAGAGGGCTGAACTCAAGATTGGAAGCAA
CTGCAGCCTCCTCAGTTAAAACACGTATGCAAAAACTTGCAGAGCAACGGCGCCGTTGGGATAATGATGATATGACAGGTGAATCTGGAT
TGGGAAAGTCGACATTAATCAACTCATTATTCCTCACAGATTTGTATTCTCCAGAGTATCCAGGTCCTTCTCATAGAATTAAAAAGACTG
TACAGGTGGAACAATCCAAAGTTTTAATCAAAGAAGGTGGTGTTCAGTTGCTGCTCACAATAGTTGATACCCCAGGATTTGGAGATGCAG
TGGATAATAGTAATTGCTGGCAGCCTGTTATCGACTACATTGATAGTAAATTTGAGGACTACCTAAATGCAGAATCACGAGTGAACAGAC
GTCAGATGCCTGATAACAGGGTGCAGTGTTGTTTATACTTCATTGCTCCTTCAGGACATGGACTTAAACCATTGGATATTGAGTTTATGA
AGCGTTTGCATGAAAAAGTGAATATCATCCCACTTATTGCCAAAGCAGACACACTCACACCAGAGGAATGCCAACAGTTTAAAAAACAGA
TAATGAAAGAAATCCAAGAACATAAAATTAAAATATACGAATTTCCAGAAACAGATGATGAAGAAGAAAATAAACTTGTTAAAAAGATAA
AGGACCGTTTACCTCTTGCTGTGGTAGGTAGTAATACTATCATTGAAGTTAATGGCAAAAGGGTCAGAGGAAGGCAGTATCCTTGGGGTG
TTGCTGAAGTTGAAAATGGTGAACATTGTGATTTTACAATCCTAAGAAATATGTTGATAAGAACACACATGCAGGACTTGAAAGATGTTA
CTAATAATGTCCACTATGAGAACTACAGAAGCAGAAAACTTGCAGCTGTGACTTATAATGGAGTTGATAACAACAAGAATAAAGGGCAGC
TGACTAAGAGCCCTCTGGCACAAATGGAAGAAGAAAGAAGGGAGCATGTAGCTAAAATGAAGAAGATGGAGATGGAGATGGAGCAGGTGT
TTGAGATGAAGGTCAAAGAAAAAGTTCAAAAACTGAAGGACTCTGAAGCTGAGCTCCAGCGGCGCCATGAGCAAATGAAAAAGAATTTGG
AAGCACAGCACAAAGAATTGGAGGAAAAACGTCGTCAGTTCGAGGATGAGAAAGCAAACTGGGAAGCTCAACAACGTATTTTAGAACAAC
AGAACTCTTCAAGAACCTTGGAAAAGAACAAGAAGAAAGGGAAGATCTTTTAAACTCTCTATTGACCACCAGTTAACGTATTAGTTGCCA
ATATGCCAGCTTGGACATCAGTGTTTGTTGGATCCGTTTGACCAATTTGCACCAGTTTTATCCATAATGATGGATTTAACAGCATGACAA
AAATTATTTTTTTTTTTGTTCTTGATGGAGATTAAGATGCCTTGAATTGTCTAGGGTGTTCTGTACTTAGAAAGTAAGAGCTCTAAGTAC
CTTTCCTACATTTTCTTTTTTTATTAAACAGATATCTTCAGTTTAATGCAAGAGAACATTTTACTGTTGTACAATCATGTTCTGGTGGTT
TGATTGTTTACAGGATATTCCAAAATAAAAGGACTCTGGAAGATTTTCATTGAGGATAAATTGCCATAATATGATGCAAACTGTGCTTCT
CTATGATAATTACAATACAAAGGTTCCATTCAGTGCAGCATATACAATAATGTAATTTAGTCTAACACAGTTGACCCTATTTTTTGACAC
TTCCATTGTTTAAAAATACACATGGAAAAAAAAAAAACCCTATATGCTTACTGTGCACCTAGAGCTTTTTTATAACAACGTCTTTTTGTT
TGTTTGTTTTGGATTCTTTAAATATATATTATTCTCATTTAGTGCCCTCTTTAGCCAGAATCTCATTACTGCTTCATTTTTGTAATAACA
TTTAATTTAGATATTTTCCATATATTGGCACTGCTAAAATAGAATATAGCATCTTTCATATGGTAGGAACCAACAAGGAAACTTTCCTTT
AACTCCCTTTTTACACTTTATGGTAAGTAGCAGGGGGGGAAATGCATTTATAGATCATTTCTAGGCAAAATTGTGAAGCTAATGACCAAC
CTGTTTCTACCTATATGCAGTCTCTTTATTTTACTAGAAATGGGAATCATGGCCTCTTGAAGAGAAAAAAGTCACCATTCTGCATTTAGC

>4835_4835_3_ANLN-SEPT7_ANLN_chr7_36439002_ENST00000265748_SEPT7_chr7_35903162_ENST00000399035_length(amino acids)=543AA_BP=162
MDPFTEKLLERTRARRENLQRKMAERPTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKSCTKPSPSKKRCSDNTEVEVSNLENKQPVES
TSAKSCSPSPVSPQVQPQAADTISDSVAVPASLLGMRRGLNSRLEATAASSVKTRMQKLAEQRRRWDNDDMTGESGLGKSTLINSLFLTD
LYSPEYPGPSHRIKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESRVNRRQMPDNRVQCCLYF
IAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFKKQIMKEIQEHKIKIYEFPETDDEEENKLVKKIKDRLPLAVVGSNTI
IEVNGKRVRGRQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDNNKNKGQLTKSPLAQMEEERR
EHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHEQMKKNLEAQHKELEEKRRQFEDEKANWEAQQRILEQQNSSRTLEKNKKKG

--------------------------------------------------------------
>4835_4835_4_ANLN-SEPT7_ANLN_chr7_36439002_ENST00000265748_SEPT7_chr7_35903162_ENST00000435235_length(transcript)=2867nt_BP=708nt
AGCGCGCATGCTCGCGGCTCGGCGCTGAAATTCAAATTTGAACGGCTGCAGAGGCCGAGTCCGTCACTGGAAGCCGAGAGGAGAGGACAG
CTGGTTGTGGGAGAGTTCCCCCGCCTCAGACTCCTGGTTTTTTCCAGGAGACACACTGAGCTGAGACTCACTTTTCTCTTCCTGAATTTG
AACCACCGTTTCCATCGTCTCGTAGTCCGACGCCTGGGGCGATGGATCCGTTTACGGAGAAACTGCTGGAGCGAACCCGTGCCAGGCGAG
AGAATCTTCAGAGAAAAATGGCTGAGAGGCCCACAGCAGCTCCAAGGTCTATGACTCATGCTAAGCGAGCTAGACAGCCACTTTCAGAAG
CAAGTAACCAGCAGCCCCTCTCTGGTGGTGAAGAGAAATCTTGTACAAAACCATCGCCATCAAAAAAACGCTGTTCTGACAACACTGAAG
TAGAAGTTTCTAACTTGGAAAATAAACAACCAGTTGAGTCGACATCTGCAAAATCTTGTTCTCCAAGTCCTGTGTCTCCTCAGGTGCAGC
CACAAGCAGCAGATACCATCAGTGATTCTGTTGCTGTCCCGGCATCACTGCTGGGCATGAGGAGAGGGCTGAACTCAAGATTGGAAGCAA
CTGCAGCCTCCTCAGTTAAAACACGTATGCAAAAACTTGCAGAGCAACGGCGCCGTTGGGATAATGATGATATGACAGGTGAATCTGGAT
TGGGAAAGTCGACATTAATCAACTCATTATTCCTCACAGATTTGTATTCTCCAGAGTATCCAGGTCCTTCTCATAGAATTAAAAAGACTG
TACAGGTGGAACAATCCAAAGTTTTAATCAAAGAAGGTGGTGTTCAGTTGCTGCTCACAATAGTTGATACCCCAGGATTTGGAGATGCAG
TGGATAATAGTAATTGCTGGCAGCCTGTTATCGACTACATTGATAGTAAATTTGAGGACTACCTAAATGCAGAATCACGAGTGAACAGAC
GTCAGATGCCTGATAACAGGGTGCAGTGTTGTTTATACTTCATTGCTCCTTCAGGACATGGACTTAAACCATTGGATATTGAGTTTATGA
AGCGTTTGCATGAAAAAGTGAATATCATCCCACTTATTGCCAAAGCAGACACACTCACACCAGAGGAATGCCAACAGTTTAAAAAACAGA
TAATGAAAGAAATCCAAGAACATAAAATTAAAATATACGAATTTCCAGAAACAGATGATGAAGAAGAAAATAAACTTGTTAAAAAGATAA
AGGACCGTTTACCTCTTGCTGTGGTAGGTAGTAATACTATCATTGAAGTTAATGGCAAAAGGGTCAGAGGAAGGCAGTATCCTTGGGGTG
TTGCTGAAGTTGAAAATGGTGAACATTGTGATTTTACAATCCTAAGAAATATGTTGATAAGAACACACATGCAGGACTTGAAAGATGTTA
CTAATAATGTCCACTATGAGAACTACAGAAGCAGAAAACTTGCAGCTGTGACTTATAATGGAGTTGATAACAACAAGAATAAAGGGCAGC
TGACTAAGAGCCCTCTGGCACAAATGGAAGAAGAAAGAAGGGAGCATGTAGCTAAAATGAAGAAGATGGAGATGGAGATGGAGCAGGTGT
TTGAGATGAAGGTCAAAGAAAAAGTTCAAAAACTGAAGGACTCTGAAGCTGAGCTCCAGCGGCGCCATGAGCAAATGAAAAAGAATTTGG
AAGCACAGCACAAAGAATTGGAGGAAAAACGTCGTCAGTTCGAGGATGAGAAAGCAAACTGGGAAGCTCAACAACGTATTTTAGAACAAC
AGAACTCTTCAAGAACCTTGGAAAAGAACAAGAAGAAAGGGAAGATCTTTTAAACTCTCTATTGACCACCAGTTAACGTATTAGTTGCCA
ATATGCCAGCTTGGACATCAGTGTTTGTTGGATCCGTTTGACCAATTTGCACCAGTTTTATCCATAATGATGGATTTAACAGCATGACAA
AAATTATTTTTTTTTTTGTTCTTGATGGAGATTAAGATGCCTTGAATTGTCTAGGGTGTTCTGTACTTAGAAAGTAAGAGCTCTAAGTAC
CTTTCCTACATTTTCTTTTTTTATTAAACAGATATCTTCAGTTTAATGCAAGAGAACATTTTACTGTTGTACAATCATGTTCTGGTGGTT
TGATTGTTTACAGGATATTCCAAAATAAAAGGACTCTGGAAGATTTTCATTGAGGATAAATTGCCATAATATGATGCAAACTGTGCTTCT
CTATGATAATTACAATACAAAGGTTCCATTCAGTGCAGCATATACAATAATGTAATTTAGTCTAACACAGTTGACCCTATTTTTTGACAC
TTCCATTGTTTAAAAATACACATGGAAAAAAAAAAAACCCTATATGCTTACTGTGCACCTAGAGCTTTTTTATAACAACGTCTTTTTGTT
TGTTTGTTTTGGATTCTTTAAATATATATTATTCTCATTTAGTGCCCTCTTTAGCCAGAATCTCATTACTGCTTCATTTTTGTAATAACA
TTTAATTTAGATATTTTCCATATATTGGCACTGCTAAAATAGAATATAGCATCTTTCATATGGTAGGAACCAACAAGGAAACTTTCCTTT
AACTCCCTTTTTACACTTTATGGTAAGTAGCAGGGGGGGAAATGCATTTATAGATCATTTCTAGGCAAAATTGTGAAGCTAATGACCAAC
CTGTTTCTACCTATATGCAGTCTCTTTATTTTACTAGAAATGGGAATCATGGCCTCTTGAAGAGAAAAAAGTCACCATTCTGCATTTAGC

>4835_4835_4_ANLN-SEPT7_ANLN_chr7_36439002_ENST00000265748_SEPT7_chr7_35903162_ENST00000435235_length(amino acids)=543AA_BP=162
MDPFTEKLLERTRARRENLQRKMAERPTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKSCTKPSPSKKRCSDNTEVEVSNLENKQPVES
TSAKSCSPSPVSPQVQPQAADTISDSVAVPASLLGMRRGLNSRLEATAASSVKTRMQKLAEQRRRWDNDDMTGESGLGKSTLINSLFLTD
LYSPEYPGPSHRIKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESRVNRRQMPDNRVQCCLYF
IAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFKKQIMKEIQEHKIKIYEFPETDDEEENKLVKKIKDRLPLAVVGSNTI
IEVNGKRVRGRQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDNNKNKGQLTKSPLAQMEEERR
EHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHEQMKKNLEAQHKELEEKRRQFEDEKANWEAQQRILEQQNSSRTLEKNKKKG

--------------------------------------------------------------
>4835_4835_5_ANLN-SEPT7_ANLN_chr7_36439002_ENST00000265748_SEPT7_chr7_35903162_ENST00000469679_length(transcript)=1247nt_BP=708nt
AGCGCGCATGCTCGCGGCTCGGCGCTGAAATTCAAATTTGAACGGCTGCAGAGGCCGAGTCCGTCACTGGAAGCCGAGAGGAGAGGACAG
CTGGTTGTGGGAGAGTTCCCCCGCCTCAGACTCCTGGTTTTTTCCAGGAGACACACTGAGCTGAGACTCACTTTTCTCTTCCTGAATTTG
AACCACCGTTTCCATCGTCTCGTAGTCCGACGCCTGGGGCGATGGATCCGTTTACGGAGAAACTGCTGGAGCGAACCCGTGCCAGGCGAG
AGAATCTTCAGAGAAAAATGGCTGAGAGGCCCACAGCAGCTCCAAGGTCTATGACTCATGCTAAGCGAGCTAGACAGCCACTTTCAGAAG
CAAGTAACCAGCAGCCCCTCTCTGGTGGTGAAGAGAAATCTTGTACAAAACCATCGCCATCAAAAAAACGCTGTTCTGACAACACTGAAG
TAGAAGTTTCTAACTTGGAAAATAAACAACCAGTTGAGTCGACATCTGCAAAATCTTGTTCTCCAAGTCCTGTGTCTCCTCAGGTGCAGC
CACAAGCAGCAGATACCATCAGTGATTCTGTTGCTGTCCCGGCATCACTGCTGGGCATGAGGAGAGGGCTGAACTCAAGATTGGAAGCAA
CTGCAGCCTCCTCAGTTAAAACACGTATGCAAAAACTTGCAGAGCAACGGCGCCGTTGGGATAATGATGATATGACAGGTGAATCTGGAT
TGGGAAAGTCGACATTAATCAACTCATTATTCCTCACAGATTTGTATTCTCCAGAGTATCCAGGTCCTTCTCATAGAATTAAAAAGACTG
TACAGGTGGAACAATCCAAAGTTTTAATCAAAGAAGGTGGTGTTCAGTTGCTGCTCACAATAGTTGATACCCCAGGATTTGGAGATGCAG
TGGATAATAGTAATTGCTGGCAGCCTGTTATCGACTACATTGATAGTAAATTTGAGGACTACCTAAATGCAGAATCACGAGTGAACAGAC
GTCAGATGCCTGATAACAGGGTGCAGTGTTGTTTATACTTCATTGCTCCTTCAGGACATGGACTTAAACCATTGGATATTGAGTTTATGA
AGCGTTTGCATGAAAAAGTGAATATCATCCCACTTATTGCCAAAGCAGACACACTCACACCAGAGGAATGCCAACAGTTTAAAAAACAGA

>4835_4835_5_ANLN-SEPT7_ANLN_chr7_36439002_ENST00000265748_SEPT7_chr7_35903162_ENST00000469679_length(amino acids)=342AA_BP=162
MDPFTEKLLERTRARRENLQRKMAERPTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKSCTKPSPSKKRCSDNTEVEVSNLENKQPVES
TSAKSCSPSPVSPQVQPQAADTISDSVAVPASLLGMRRGLNSRLEATAASSVKTRMQKLAEQRRRWDNDDMTGESGLGKSTLINSLFLTD
LYSPEYPGPSHRIKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESRVNRRQMPDNRVQCCLYF

--------------------------------------------------------------
>4835_4835_6_ANLN-SEPT7_ANLN_chr7_36439002_ENST00000396068_SEPT7_chr7_35903162_ENST00000350320_length(transcript)=2850nt_BP=693nt
GGCTCGGCGCTGAAATTCAAATTTGAACGGCTGCAGAGGCCGAGTCCGTCACTGGAAGCCGAGAGGAGAGGACAGCTGGTTGTGGGAGAG
TTCCCCCGCCTCAGACTCCTGGTTTTTTCCAGGAGACACACTGAGCTGAGACTCACTTTTCTCTTCCTGAATTTGAACCACCGTTTCCAT
CGTCTCGTAGTCCGACGCCTGGGGCGATGGATCCGTTTACGGAGAAACTGCTGGAGCGAACCCGTGCCAGGCGAGAGAATCTTCAGAGAA
AAATGGCTGAGAGGCCCACAGCAGCTCCAAGGTCTATGACTCATGCTAAGCGAGCTAGACAGCCACTTTCAGAAGCAAGTAACCAGCAGC
CCCTCTCTGGTGGTGAAGAGAAATCTTGTACAAAACCATCGCCATCAAAAAAACGCTGTTCTGACAACACTGAAGTAGAAGTTTCTAACT
TGGAAAATAAACAACCAGTTGAGTCGACATCTGCAAAATCTTGTTCTCCAAGTCCTGTGTCTCCTCAGGTGCAGCCACAAGCAGCAGATA
CCATCAGTGATTCTGTTGCTGTCCCGGCATCACTGCTGGGCATGAGGAGAGGGCTGAACTCAAGATTGGAAGCAACTGCAGCCTCCTCAG
TTAAAACACGTATGCAAAAACTTGCAGAGCAACGGCGCCGTTGGGATAATGATGATATGACAGGTGAATCTGGATTGGGAAAGTCGACAT
TAATCAACTCATTATTCCTCACAGATTTGTATTCTCCAGAGTATCCAGGTCCTTCTCATAGAATTAAAAAGACTGTACAGGTGGAACAAT
CCAAAGTTTTAATCAAAGAAGGTGGTGTTCAGTTGCTGCTCACAATAGTTGATACCCCAGGATTTGGAGATGCAGTGGATAATAGTAATT
GCTGGCAGCCTGTTATCGACTACATTGATAGTAAATTTGAGGACTACCTAAATGCAGAATCACGAGTGAACAGACGTCAGATGCCTGATA
ACAGGGTGCAGTGTTGTTTATACTTCATTGCTCCTTCAGGACATGGACTTAAACCATTGGATATTGAGTTTATGAAGCGTTTGCATGAAA
AAGTGAATATCATCCCACTTATTGCCAAAGCAGACACACTCACACCAGAGGAATGCCAACAGTTTAAAAAACAGATAATGAAAGAAATCC
AAGAACATAAAATTAAAATATACGAATTTCCAGAAACAGATGATGAAGAAGAAAATAAACTTGTTAAAAAGATAAAGGACCGTTTACCTC
TTGCTGTGGTAGGTAGTAATACTATCATTGAAGTTAATGGCAAAAGGGTCAGAGGAAGGCAGTATCCTTGGGGTGTTGCTGAAGTTGAAA
ATGGTGAACATTGTGATTTTACAATCCTAAGAAATATGTTGATAAGAACACACATGCAGGACTTGAAAGATGTTACTAATAATGTCCACT
ATGAGAACTACAGAAGCAGAAAACTTGCAGCTGTGACTTATAATGGAGTTGATAACAACAAGAATAAAGGGCAGCTGACTAAGAGCCCTC
TGGCACAAATGGAAGAAGAAAGAAGGGAGCATGTAGCTAAAATGAAGAAGATGGAGATGGAGATGGAGCAGGTGTTTGAGATGAAGGTCA
AAGAAAAAGTTCAAAAACTGAAGGACTCTGAAGCTGAGCTCCAGCGGCGCCATGAGCAAATGAAAAAGAATTTGGAAGCACAGCACAAAG
AATTGGAGGAAAAACGTCGTCAGTTCGAGGATGAGAAAGCAAACTGGGAAGCTCAACAACGTATTTTAGAACAACAGAACTCTTCAAGAA
CCTTGGAAAAGAACAAGAAGAAAGGGAAGATCTTTTAAACTCTCTATTGACCACCAGTTAACGTATTAGTTGCCAATATGCCAGCTTGGA
CATCAGTGTTTGTTGGATCCGTTTGACCAATTTGCACCAGTTTTATCCATAATGATGGATTTAACAGCATGACAAAAATTATTTTTTTTT
TTGTTCTTGATGGAGATTAAGATGCCTTGAATTGTCTAGGGTGTTCTGTACTTAGAAAGTAAGAGCTCTAAGTACCTTTCCTACATTTTC
TTTTTTTATTAAACAGATATCTTCAGTTTAATGCAAGAGAACATTTTACTGTTGTACAATCATGTTCTGGTGGTTTGATTGTTTACAGGA
TATTCCAAAATAAAAGGACTCTGGAAGATTTTCATTGAGGATAAATTGCCATAATATGATGCAAACTGTGCTTCTCTATGATAATTACAA
TACAAAGGTTCCATTCAGTGCAGCATATACAATAATGTAATTTAGTCTAACACAGTTGACCCTATTTTTTGACACTTCCATTGTTTAAAA
ATACACATGGAAAAAAAAAAAACCCTATATGCTTACTGTGCACCTAGAGCTTTTTTATAACAACGTCTTTTTGTTTGTTTGTTTTGGATT
CTTTAAATATATATTATTCTCATTTAGTGCCCTCTTTAGCCAGAATCTCATTACTGCTTCATTTTTGTAATAACATTTAATTTAGATATT
TTCCATATATTGGCACTGCTAAAATAGAATATAGCATCTTTCATATGGTAGGAACCAACAAGGAAACTTTCCTTTAACTCCCTTTTTACA
CTTTATGGTAAGTAGCAGGGGGGGAAATGCATTTATAGATCATTTCTAGGCAAAATTGTGAAGCTAATGACCAACCTGTTTCTACCTATA
TGCAGTCTCTTTATTTTACTAGAAATGGGAATCATGGCCTCTTGAAGAGAAAAAAGTCACCATTCTGCATTTAGCTGTATTCATATATTG

>4835_4835_6_ANLN-SEPT7_ANLN_chr7_36439002_ENST00000396068_SEPT7_chr7_35903162_ENST00000350320_length(amino acids)=543AA_BP=162
MDPFTEKLLERTRARRENLQRKMAERPTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKSCTKPSPSKKRCSDNTEVEVSNLENKQPVES
TSAKSCSPSPVSPQVQPQAADTISDSVAVPASLLGMRRGLNSRLEATAASSVKTRMQKLAEQRRRWDNDDMTGESGLGKSTLINSLFLTD
LYSPEYPGPSHRIKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESRVNRRQMPDNRVQCCLYF
IAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFKKQIMKEIQEHKIKIYEFPETDDEEENKLVKKIKDRLPLAVVGSNTI
IEVNGKRVRGRQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDNNKNKGQLTKSPLAQMEEERR
EHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHEQMKKNLEAQHKELEEKRRQFEDEKANWEAQQRILEQQNSSRTLEKNKKKG

--------------------------------------------------------------
>4835_4835_7_ANLN-SEPT7_ANLN_chr7_36439002_ENST00000396068_SEPT7_chr7_35903162_ENST00000399034_length(transcript)=2850nt_BP=693nt
GGCTCGGCGCTGAAATTCAAATTTGAACGGCTGCAGAGGCCGAGTCCGTCACTGGAAGCCGAGAGGAGAGGACAGCTGGTTGTGGGAGAG
TTCCCCCGCCTCAGACTCCTGGTTTTTTCCAGGAGACACACTGAGCTGAGACTCACTTTTCTCTTCCTGAATTTGAACCACCGTTTCCAT
CGTCTCGTAGTCCGACGCCTGGGGCGATGGATCCGTTTACGGAGAAACTGCTGGAGCGAACCCGTGCCAGGCGAGAGAATCTTCAGAGAA
AAATGGCTGAGAGGCCCACAGCAGCTCCAAGGTCTATGACTCATGCTAAGCGAGCTAGACAGCCACTTTCAGAAGCAAGTAACCAGCAGC
CCCTCTCTGGTGGTGAAGAGAAATCTTGTACAAAACCATCGCCATCAAAAAAACGCTGTTCTGACAACACTGAAGTAGAAGTTTCTAACT
TGGAAAATAAACAACCAGTTGAGTCGACATCTGCAAAATCTTGTTCTCCAAGTCCTGTGTCTCCTCAGGTGCAGCCACAAGCAGCAGATA
CCATCAGTGATTCTGTTGCTGTCCCGGCATCACTGCTGGGCATGAGGAGAGGGCTGAACTCAAGATTGGAAGCAACTGCAGCCTCCTCAG
TTAAAACACGTATGCAAAAACTTGCAGAGCAACGGCGCCGTTGGGATAATGATGATATGACAGGTGAATCTGGATTGGGAAAGTCGACAT
TAATCAACTCATTATTCCTCACAGATTTGTATTCTCCAGAGTATCCAGGTCCTTCTCATAGAATTAAAAAGACTGTACAGGTGGAACAAT
CCAAAGTTTTAATCAAAGAAGGTGGTGTTCAGTTGCTGCTCACAATAGTTGATACCCCAGGATTTGGAGATGCAGTGGATAATAGTAATT
GCTGGCAGCCTGTTATCGACTACATTGATAGTAAATTTGAGGACTACCTAAATGCAGAATCACGAGTGAACAGACGTCAGATGCCTGATA
ACAGGGTGCAGTGTTGTTTATACTTCATTGCTCCTTCAGGACATGGACTTAAACCATTGGATATTGAGTTTATGAAGCGTTTGCATGAAA
AAGTGAATATCATCCCACTTATTGCCAAAGCAGACACACTCACACCAGAGGAATGCCAACAGTTTAAAAAACAGATAATGAAAGAAATCC
AAGAACATAAAATTAAAATATACGAATTTCCAGAAACAGATGATGAAGAAGAAAATAAACTTGTTAAAAAGATAAAGGACCGTTTACCTC
TTGCTGTGGTAGGTAGTAATACTATCATTGAAGTTAATGGCAAAAGGGTCAGAGGAAGGCAGTATCCTTGGGGTGTTGCTGAAGTTGAAA
ATGGTGAACATTGTGATTTTACAATCCTAAGAAATATGTTGATAAGAACACACATGCAGGACTTGAAAGATGTTACTAATAATGTCCACT
ATGAGAACTACAGAAGCAGAAAACTTGCAGCTGTGACTTATAATGGAGTTGATAACAACAAGAATAAAGGGCAGCTGACTAAGAGCCCTC
TGGCACAAATGGAAGAAGAAAGAAGGGAGCATGTAGCTAAAATGAAGAAGATGGAGATGGAGATGGAGCAGGTGTTTGAGATGAAGGTCA
AAGAAAAAGTTCAAAAACTGAAGGACTCTGAAGCTGAGCTCCAGCGGCGCCATGAGCAAATGAAAAAGAATTTGGAAGCACAGCACAAAG
AATTGGAGGAAAAACGTCGTCAGTTCGAGGATGAGAAAGCAAACTGGGAAGCTCAACAACGTATTTTAGAACAACAGAACTCTTCAAGAA
CCTTGGAAAAGAACAAGAAGAAAGGGAAGATCTTTTAAACTCTCTATTGACCACCAGTTAACGTATTAGTTGCCAATATGCCAGCTTGGA
CATCAGTGTTTGTTGGATCCGTTTGACCAATTTGCACCAGTTTTATCCATAATGATGGATTTAACAGCATGACAAAAATTATTTTTTTTT
TTGTTCTTGATGGAGATTAAGATGCCTTGAATTGTCTAGGGTGTTCTGTACTTAGAAAGTAAGAGCTCTAAGTACCTTTCCTACATTTTC
TTTTTTTATTAAACAGATATCTTCAGTTTAATGCAAGAGAACATTTTACTGTTGTACAATCATGTTCTGGTGGTTTGATTGTTTACAGGA
TATTCCAAAATAAAAGGACTCTGGAAGATTTTCATTGAGGATAAATTGCCATAATATGATGCAAACTGTGCTTCTCTATGATAATTACAA
TACAAAGGTTCCATTCAGTGCAGCATATACAATAATGTAATTTAGTCTAACACAGTTGACCCTATTTTTTGACACTTCCATTGTTTAAAA
ATACACATGGAAAAAAAAAAAACCCTATATGCTTACTGTGCACCTAGAGCTTTTTTATAACAACGTCTTTTTGTTTGTTTGTTTTGGATT
CTTTAAATATATATTATTCTCATTTAGTGCCCTCTTTAGCCAGAATCTCATTACTGCTTCATTTTTGTAATAACATTTAATTTAGATATT
TTCCATATATTGGCACTGCTAAAATAGAATATAGCATCTTTCATATGGTAGGAACCAACAAGGAAACTTTCCTTTAACTCCCTTTTTACA
CTTTATGGTAAGTAGCAGGGGGGGAAATGCATTTATAGATCATTTCTAGGCAAAATTGTGAAGCTAATGACCAACCTGTTTCTACCTATA
TGCAGTCTCTTTATTTTACTAGAAATGGGAATCATGGCCTCTTGAAGAGAAAAAAGTCACCATTCTGCATTTAGCTGTATTCATATATTG

>4835_4835_7_ANLN-SEPT7_ANLN_chr7_36439002_ENST00000396068_SEPT7_chr7_35903162_ENST00000399034_length(amino acids)=543AA_BP=162
MDPFTEKLLERTRARRENLQRKMAERPTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKSCTKPSPSKKRCSDNTEVEVSNLENKQPVES
TSAKSCSPSPVSPQVQPQAADTISDSVAVPASLLGMRRGLNSRLEATAASSVKTRMQKLAEQRRRWDNDDMTGESGLGKSTLINSLFLTD
LYSPEYPGPSHRIKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESRVNRRQMPDNRVQCCLYF
IAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFKKQIMKEIQEHKIKIYEFPETDDEEENKLVKKIKDRLPLAVVGSNTI
IEVNGKRVRGRQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDNNKNKGQLTKSPLAQMEEERR
EHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHEQMKKNLEAQHKELEEKRRQFEDEKANWEAQQRILEQQNSSRTLEKNKKKG

--------------------------------------------------------------
>4835_4835_8_ANLN-SEPT7_ANLN_chr7_36439002_ENST00000396068_SEPT7_chr7_35903162_ENST00000399035_length(transcript)=2850nt_BP=693nt
GGCTCGGCGCTGAAATTCAAATTTGAACGGCTGCAGAGGCCGAGTCCGTCACTGGAAGCCGAGAGGAGAGGACAGCTGGTTGTGGGAGAG
TTCCCCCGCCTCAGACTCCTGGTTTTTTCCAGGAGACACACTGAGCTGAGACTCACTTTTCTCTTCCTGAATTTGAACCACCGTTTCCAT
CGTCTCGTAGTCCGACGCCTGGGGCGATGGATCCGTTTACGGAGAAACTGCTGGAGCGAACCCGTGCCAGGCGAGAGAATCTTCAGAGAA
AAATGGCTGAGAGGCCCACAGCAGCTCCAAGGTCTATGACTCATGCTAAGCGAGCTAGACAGCCACTTTCAGAAGCAAGTAACCAGCAGC
CCCTCTCTGGTGGTGAAGAGAAATCTTGTACAAAACCATCGCCATCAAAAAAACGCTGTTCTGACAACACTGAAGTAGAAGTTTCTAACT
TGGAAAATAAACAACCAGTTGAGTCGACATCTGCAAAATCTTGTTCTCCAAGTCCTGTGTCTCCTCAGGTGCAGCCACAAGCAGCAGATA
CCATCAGTGATTCTGTTGCTGTCCCGGCATCACTGCTGGGCATGAGGAGAGGGCTGAACTCAAGATTGGAAGCAACTGCAGCCTCCTCAG
TTAAAACACGTATGCAAAAACTTGCAGAGCAACGGCGCCGTTGGGATAATGATGATATGACAGGTGAATCTGGATTGGGAAAGTCGACAT
TAATCAACTCATTATTCCTCACAGATTTGTATTCTCCAGAGTATCCAGGTCCTTCTCATAGAATTAAAAAGACTGTACAGGTGGAACAAT
CCAAAGTTTTAATCAAAGAAGGTGGTGTTCAGTTGCTGCTCACAATAGTTGATACCCCAGGATTTGGAGATGCAGTGGATAATAGTAATT
GCTGGCAGCCTGTTATCGACTACATTGATAGTAAATTTGAGGACTACCTAAATGCAGAATCACGAGTGAACAGACGTCAGATGCCTGATA
ACAGGGTGCAGTGTTGTTTATACTTCATTGCTCCTTCAGGACATGGACTTAAACCATTGGATATTGAGTTTATGAAGCGTTTGCATGAAA
AAGTGAATATCATCCCACTTATTGCCAAAGCAGACACACTCACACCAGAGGAATGCCAACAGTTTAAAAAACAGATAATGAAAGAAATCC
AAGAACATAAAATTAAAATATACGAATTTCCAGAAACAGATGATGAAGAAGAAAATAAACTTGTTAAAAAGATAAAGGACCGTTTACCTC
TTGCTGTGGTAGGTAGTAATACTATCATTGAAGTTAATGGCAAAAGGGTCAGAGGAAGGCAGTATCCTTGGGGTGTTGCTGAAGTTGAAA
ATGGTGAACATTGTGATTTTACAATCCTAAGAAATATGTTGATAAGAACACACATGCAGGACTTGAAAGATGTTACTAATAATGTCCACT
ATGAGAACTACAGAAGCAGAAAACTTGCAGCTGTGACTTATAATGGAGTTGATAACAACAAGAATAAAGGGCAGCTGACTAAGAGCCCTC
TGGCACAAATGGAAGAAGAAAGAAGGGAGCATGTAGCTAAAATGAAGAAGATGGAGATGGAGATGGAGCAGGTGTTTGAGATGAAGGTCA
AAGAAAAAGTTCAAAAACTGAAGGACTCTGAAGCTGAGCTCCAGCGGCGCCATGAGCAAATGAAAAAGAATTTGGAAGCACAGCACAAAG
AATTGGAGGAAAAACGTCGTCAGTTCGAGGATGAGAAAGCAAACTGGGAAGCTCAACAACGTATTTTAGAACAACAGAACTCTTCAAGAA
CCTTGGAAAAGAACAAGAAGAAAGGGAAGATCTTTTAAACTCTCTATTGACCACCAGTTAACGTATTAGTTGCCAATATGCCAGCTTGGA
CATCAGTGTTTGTTGGATCCGTTTGACCAATTTGCACCAGTTTTATCCATAATGATGGATTTAACAGCATGACAAAAATTATTTTTTTTT
TTGTTCTTGATGGAGATTAAGATGCCTTGAATTGTCTAGGGTGTTCTGTACTTAGAAAGTAAGAGCTCTAAGTACCTTTCCTACATTTTC
TTTTTTTATTAAACAGATATCTTCAGTTTAATGCAAGAGAACATTTTACTGTTGTACAATCATGTTCTGGTGGTTTGATTGTTTACAGGA
TATTCCAAAATAAAAGGACTCTGGAAGATTTTCATTGAGGATAAATTGCCATAATATGATGCAAACTGTGCTTCTCTATGATAATTACAA
TACAAAGGTTCCATTCAGTGCAGCATATACAATAATGTAATTTAGTCTAACACAGTTGACCCTATTTTTTGACACTTCCATTGTTTAAAA
ATACACATGGAAAAAAAAAAAACCCTATATGCTTACTGTGCACCTAGAGCTTTTTTATAACAACGTCTTTTTGTTTGTTTGTTTTGGATT
CTTTAAATATATATTATTCTCATTTAGTGCCCTCTTTAGCCAGAATCTCATTACTGCTTCATTTTTGTAATAACATTTAATTTAGATATT
TTCCATATATTGGCACTGCTAAAATAGAATATAGCATCTTTCATATGGTAGGAACCAACAAGGAAACTTTCCTTTAACTCCCTTTTTACA
CTTTATGGTAAGTAGCAGGGGGGGAAATGCATTTATAGATCATTTCTAGGCAAAATTGTGAAGCTAATGACCAACCTGTTTCTACCTATA
TGCAGTCTCTTTATTTTACTAGAAATGGGAATCATGGCCTCTTGAAGAGAAAAAAGTCACCATTCTGCATTTAGCTGTATTCATATATTG

>4835_4835_8_ANLN-SEPT7_ANLN_chr7_36439002_ENST00000396068_SEPT7_chr7_35903162_ENST00000399035_length(amino acids)=543AA_BP=162
MDPFTEKLLERTRARRENLQRKMAERPTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKSCTKPSPSKKRCSDNTEVEVSNLENKQPVES
TSAKSCSPSPVSPQVQPQAADTISDSVAVPASLLGMRRGLNSRLEATAASSVKTRMQKLAEQRRRWDNDDMTGESGLGKSTLINSLFLTD
LYSPEYPGPSHRIKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESRVNRRQMPDNRVQCCLYF
IAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFKKQIMKEIQEHKIKIYEFPETDDEEENKLVKKIKDRLPLAVVGSNTI
IEVNGKRVRGRQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDNNKNKGQLTKSPLAQMEEERR
EHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHEQMKKNLEAQHKELEEKRRQFEDEKANWEAQQRILEQQNSSRTLEKNKKKG

--------------------------------------------------------------
>4835_4835_9_ANLN-SEPT7_ANLN_chr7_36439002_ENST00000396068_SEPT7_chr7_35903162_ENST00000435235_length(transcript)=2852nt_BP=693nt
GGCTCGGCGCTGAAATTCAAATTTGAACGGCTGCAGAGGCCGAGTCCGTCACTGGAAGCCGAGAGGAGAGGACAGCTGGTTGTGGGAGAG
TTCCCCCGCCTCAGACTCCTGGTTTTTTCCAGGAGACACACTGAGCTGAGACTCACTTTTCTCTTCCTGAATTTGAACCACCGTTTCCAT
CGTCTCGTAGTCCGACGCCTGGGGCGATGGATCCGTTTACGGAGAAACTGCTGGAGCGAACCCGTGCCAGGCGAGAGAATCTTCAGAGAA
AAATGGCTGAGAGGCCCACAGCAGCTCCAAGGTCTATGACTCATGCTAAGCGAGCTAGACAGCCACTTTCAGAAGCAAGTAACCAGCAGC
CCCTCTCTGGTGGTGAAGAGAAATCTTGTACAAAACCATCGCCATCAAAAAAACGCTGTTCTGACAACACTGAAGTAGAAGTTTCTAACT
TGGAAAATAAACAACCAGTTGAGTCGACATCTGCAAAATCTTGTTCTCCAAGTCCTGTGTCTCCTCAGGTGCAGCCACAAGCAGCAGATA
CCATCAGTGATTCTGTTGCTGTCCCGGCATCACTGCTGGGCATGAGGAGAGGGCTGAACTCAAGATTGGAAGCAACTGCAGCCTCCTCAG
TTAAAACACGTATGCAAAAACTTGCAGAGCAACGGCGCCGTTGGGATAATGATGATATGACAGGTGAATCTGGATTGGGAAAGTCGACAT
TAATCAACTCATTATTCCTCACAGATTTGTATTCTCCAGAGTATCCAGGTCCTTCTCATAGAATTAAAAAGACTGTACAGGTGGAACAAT
CCAAAGTTTTAATCAAAGAAGGTGGTGTTCAGTTGCTGCTCACAATAGTTGATACCCCAGGATTTGGAGATGCAGTGGATAATAGTAATT
GCTGGCAGCCTGTTATCGACTACATTGATAGTAAATTTGAGGACTACCTAAATGCAGAATCACGAGTGAACAGACGTCAGATGCCTGATA
ACAGGGTGCAGTGTTGTTTATACTTCATTGCTCCTTCAGGACATGGACTTAAACCATTGGATATTGAGTTTATGAAGCGTTTGCATGAAA
AAGTGAATATCATCCCACTTATTGCCAAAGCAGACACACTCACACCAGAGGAATGCCAACAGTTTAAAAAACAGATAATGAAAGAAATCC
AAGAACATAAAATTAAAATATACGAATTTCCAGAAACAGATGATGAAGAAGAAAATAAACTTGTTAAAAAGATAAAGGACCGTTTACCTC
TTGCTGTGGTAGGTAGTAATACTATCATTGAAGTTAATGGCAAAAGGGTCAGAGGAAGGCAGTATCCTTGGGGTGTTGCTGAAGTTGAAA
ATGGTGAACATTGTGATTTTACAATCCTAAGAAATATGTTGATAAGAACACACATGCAGGACTTGAAAGATGTTACTAATAATGTCCACT
ATGAGAACTACAGAAGCAGAAAACTTGCAGCTGTGACTTATAATGGAGTTGATAACAACAAGAATAAAGGGCAGCTGACTAAGAGCCCTC
TGGCACAAATGGAAGAAGAAAGAAGGGAGCATGTAGCTAAAATGAAGAAGATGGAGATGGAGATGGAGCAGGTGTTTGAGATGAAGGTCA
AAGAAAAAGTTCAAAAACTGAAGGACTCTGAAGCTGAGCTCCAGCGGCGCCATGAGCAAATGAAAAAGAATTTGGAAGCACAGCACAAAG
AATTGGAGGAAAAACGTCGTCAGTTCGAGGATGAGAAAGCAAACTGGGAAGCTCAACAACGTATTTTAGAACAACAGAACTCTTCAAGAA
CCTTGGAAAAGAACAAGAAGAAAGGGAAGATCTTTTAAACTCTCTATTGACCACCAGTTAACGTATTAGTTGCCAATATGCCAGCTTGGA
CATCAGTGTTTGTTGGATCCGTTTGACCAATTTGCACCAGTTTTATCCATAATGATGGATTTAACAGCATGACAAAAATTATTTTTTTTT
TTGTTCTTGATGGAGATTAAGATGCCTTGAATTGTCTAGGGTGTTCTGTACTTAGAAAGTAAGAGCTCTAAGTACCTTTCCTACATTTTC
TTTTTTTATTAAACAGATATCTTCAGTTTAATGCAAGAGAACATTTTACTGTTGTACAATCATGTTCTGGTGGTTTGATTGTTTACAGGA
TATTCCAAAATAAAAGGACTCTGGAAGATTTTCATTGAGGATAAATTGCCATAATATGATGCAAACTGTGCTTCTCTATGATAATTACAA
TACAAAGGTTCCATTCAGTGCAGCATATACAATAATGTAATTTAGTCTAACACAGTTGACCCTATTTTTTGACACTTCCATTGTTTAAAA
ATACACATGGAAAAAAAAAAAACCCTATATGCTTACTGTGCACCTAGAGCTTTTTTATAACAACGTCTTTTTGTTTGTTTGTTTTGGATT
CTTTAAATATATATTATTCTCATTTAGTGCCCTCTTTAGCCAGAATCTCATTACTGCTTCATTTTTGTAATAACATTTAATTTAGATATT
TTCCATATATTGGCACTGCTAAAATAGAATATAGCATCTTTCATATGGTAGGAACCAACAAGGAAACTTTCCTTTAACTCCCTTTTTACA
CTTTATGGTAAGTAGCAGGGGGGGAAATGCATTTATAGATCATTTCTAGGCAAAATTGTGAAGCTAATGACCAACCTGTTTCTACCTATA
TGCAGTCTCTTTATTTTACTAGAAATGGGAATCATGGCCTCTTGAAGAGAAAAAAGTCACCATTCTGCATTTAGCTGTATTCATATATTG

>4835_4835_9_ANLN-SEPT7_ANLN_chr7_36439002_ENST00000396068_SEPT7_chr7_35903162_ENST00000435235_length(amino acids)=543AA_BP=162
MDPFTEKLLERTRARRENLQRKMAERPTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKSCTKPSPSKKRCSDNTEVEVSNLENKQPVES
TSAKSCSPSPVSPQVQPQAADTISDSVAVPASLLGMRRGLNSRLEATAASSVKTRMQKLAEQRRRWDNDDMTGESGLGKSTLINSLFLTD
LYSPEYPGPSHRIKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESRVNRRQMPDNRVQCCLYF
IAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFKKQIMKEIQEHKIKIYEFPETDDEEENKLVKKIKDRLPLAVVGSNTI
IEVNGKRVRGRQYPWGVAEVENGEHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDNNKNKGQLTKSPLAQMEEERR
EHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAELQRRHEQMKKNLEAQHKELEEKRRQFEDEKANWEAQQRILEQQNSSRTLEKNKKKG

--------------------------------------------------------------
>4835_4835_10_ANLN-SEPT7_ANLN_chr7_36439002_ENST00000396068_SEPT7_chr7_35903162_ENST00000469679_length(transcript)=1232nt_BP=693nt
GGCTCGGCGCTGAAATTCAAATTTGAACGGCTGCAGAGGCCGAGTCCGTCACTGGAAGCCGAGAGGAGAGGACAGCTGGTTGTGGGAGAG
TTCCCCCGCCTCAGACTCCTGGTTTTTTCCAGGAGACACACTGAGCTGAGACTCACTTTTCTCTTCCTGAATTTGAACCACCGTTTCCAT
CGTCTCGTAGTCCGACGCCTGGGGCGATGGATCCGTTTACGGAGAAACTGCTGGAGCGAACCCGTGCCAGGCGAGAGAATCTTCAGAGAA
AAATGGCTGAGAGGCCCACAGCAGCTCCAAGGTCTATGACTCATGCTAAGCGAGCTAGACAGCCACTTTCAGAAGCAAGTAACCAGCAGC
CCCTCTCTGGTGGTGAAGAGAAATCTTGTACAAAACCATCGCCATCAAAAAAACGCTGTTCTGACAACACTGAAGTAGAAGTTTCTAACT
TGGAAAATAAACAACCAGTTGAGTCGACATCTGCAAAATCTTGTTCTCCAAGTCCTGTGTCTCCTCAGGTGCAGCCACAAGCAGCAGATA
CCATCAGTGATTCTGTTGCTGTCCCGGCATCACTGCTGGGCATGAGGAGAGGGCTGAACTCAAGATTGGAAGCAACTGCAGCCTCCTCAG
TTAAAACACGTATGCAAAAACTTGCAGAGCAACGGCGCCGTTGGGATAATGATGATATGACAGGTGAATCTGGATTGGGAAAGTCGACAT
TAATCAACTCATTATTCCTCACAGATTTGTATTCTCCAGAGTATCCAGGTCCTTCTCATAGAATTAAAAAGACTGTACAGGTGGAACAAT
CCAAAGTTTTAATCAAAGAAGGTGGTGTTCAGTTGCTGCTCACAATAGTTGATACCCCAGGATTTGGAGATGCAGTGGATAATAGTAATT
GCTGGCAGCCTGTTATCGACTACATTGATAGTAAATTTGAGGACTACCTAAATGCAGAATCACGAGTGAACAGACGTCAGATGCCTGATA
ACAGGGTGCAGTGTTGTTTATACTTCATTGCTCCTTCAGGACATGGACTTAAACCATTGGATATTGAGTTTATGAAGCGTTTGCATGAAA
AAGTGAATATCATCCCACTTATTGCCAAAGCAGACACACTCACACCAGAGGAATGCCAACAGTTTAAAAAACAGATAATGAAAGAAATCC

>4835_4835_10_ANLN-SEPT7_ANLN_chr7_36439002_ENST00000396068_SEPT7_chr7_35903162_ENST00000469679_length(amino acids)=342AA_BP=162
MDPFTEKLLERTRARRENLQRKMAERPTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKSCTKPSPSKKRCSDNTEVEVSNLENKQPVES
TSAKSCSPSPVSPQVQPQAADTISDSVAVPASLLGMRRGLNSRLEATAASSVKTRMQKLAEQRRRWDNDDMTGESGLGKSTLINSLFLTD
LYSPEYPGPSHRIKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESRVNRRQMPDNRVQCCLYF

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ANLN-SEPT7


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneANLNchr7:36439002chr7:35903162ENST00000265748+3241_155162.333333333333341125.0CD2AP
HgeneANLNchr7:36439002chr7:35903162ENST00000396068+3231_155162.333333333333341088.0CD2AP


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneANLNchr7:36439002chr7:35903162ENST00000265748+324231_676162.333333333333341125.0F-actin
HgeneANLNchr7:36439002chr7:35903162ENST00000396068+323231_676162.333333333333341088.0F-actin
TgeneSEPT7chr7:36439002chr7:35903162ENST0000039903421447_31757.333333333333336439.0SEPTIN12


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ANLN-SEPT7


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ANLN-SEPT7


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneANLNC4014993FOCAL SEGMENTAL GLOMERULOSCLEROSIS 82GENOMICS_ENGLAND;UNIPROT
HgeneANLNC0032460Polycystic Ovary Syndrome1CTD_human
HgeneANLNC1136382Sclerocystic Ovaries1CTD_human
HgeneANLNC1868672NEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE1ORPHANET
HgeneANLNC2239176Liver carcinoma1CTD_human