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Fusion Gene Summary | |
Fusion Gene ORF analysis | |
Fusion Genomic Features | |
Fusion Protein Features | |
Fusion Gene Sequence | |
Fusion Gene PPI analysis | |
Related Drugs | |
Related Diseases |
Fusion gene:ATG16L1-WAPAL (FusionGDB2 ID:HG55054TG23063) |
Fusion Gene Summary for ATG16L1-WAPAL |
Fusion gene summary |
Fusion gene information | Fusion gene name: ATG16L1-WAPAL | Fusion gene ID: hg55054tg23063 | Hgene | Tgene | Gene symbol | ATG16L1 | WAPAL | Gene ID | 55054 | 23063 |
Gene name | autophagy related 16 like 1 | WAPL cohesin release factor | |
Synonyms | APG16L|ATG16A|ATG16L|IBD10|WDR30 | FOE|KIAA0261|WAPAL | |
Cytomap | ('ATG16L1')('WAPAL') 2q37.1 | 10q23.2 | |
Type of gene | protein-coding | protein-coding | |
Description | autophagy-related protein 16-1APG16L betaATG16 autophagy related 16-like 1WD repeat domain 30 | wings apart-like protein homologfriend of EBNA2 (Epstein-Barr virus nuclear protein 2)friend of EBNA2 protein | |
Modification date | 20200320 | 20200327 | |
UniProtAcc | . | . | |
Ensembl transtripts involved in fusion gene | ENST00000498620, ENST00000347464, ENST00000373525, ENST00000392017, ENST00000392018, ENST00000392020, | ||
Fusion gene scores | * DoF score | 5 X 4 X 4=80 | 4 X 3 X 4=48 |
# samples | 5 | 5 | |
** MAII score | log2(5/80*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(5/48*10)=0.0588936890535686 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
Context | PubMed: ATG16L1 [Title/Abstract] AND WAPAL [Title/Abstract] AND fusion [Title/Abstract] | ||
Most frequent breakpoint | ATG16L1(234191399)-WAPAL(88206206), # samples:1 | ||
Anticipated loss of major functional domain due to fusion event. | ATG16L1-WAPAL seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. ATG16L1-WAPAL seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. ATG16L1-WAPAL seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. ATG16L1-WAPAL seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
Partner | Gene | GO ID | GO term | PubMed ID |
Fusion gene breakpoints across ATG16L1 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
Fusion gene breakpoints across WAPAL (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
Fusion gene information * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChimerDB4 | Non-Cancer | TCGA-BH-A18P-11A | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - |
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Fusion Gene ORF analysis for ATG16L1-WAPAL |
Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
3UTR-3CDS | ENST00000498620 | ENST00000263070 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - |
3UTR-3CDS | ENST00000498620 | ENST00000298767 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - |
3UTR-3CDS | ENST00000498620 | ENST00000372075 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - |
3UTR-intron | ENST00000498620 | ENST00000484070 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - |
5CDS-intron | ENST00000347464 | ENST00000484070 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - |
5CDS-intron | ENST00000373525 | ENST00000484070 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - |
5CDS-intron | ENST00000392017 | ENST00000484070 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - |
5CDS-intron | ENST00000392018 | ENST00000484070 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - |
5CDS-intron | ENST00000392020 | ENST00000484070 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - |
In-frame | ENST00000347464 | ENST00000263070 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - |
In-frame | ENST00000347464 | ENST00000298767 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - |
In-frame | ENST00000347464 | ENST00000372075 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - |
In-frame | ENST00000373525 | ENST00000263070 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - |
In-frame | ENST00000373525 | ENST00000298767 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - |
In-frame | ENST00000373525 | ENST00000372075 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - |
In-frame | ENST00000392017 | ENST00000263070 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - |
In-frame | ENST00000392017 | ENST00000298767 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - |
In-frame | ENST00000392017 | ENST00000372075 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - |
In-frame | ENST00000392018 | ENST00000263070 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - |
In-frame | ENST00000392018 | ENST00000298767 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - |
In-frame | ENST00000392018 | ENST00000372075 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - |
In-frame | ENST00000392020 | ENST00000263070 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - |
In-frame | ENST00000392020 | ENST00000298767 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - |
In-frame | ENST00000392020 | ENST00000372075 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - |
ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
ENST00000347464 | ATG16L1 | chr2 | 234191399 | + | ENST00000298767 | WAPAL | chr10 | 88206206 | - | 3717 | 971 | 257 | 1429 | 390 |
ENST00000347464 | ATG16L1 | chr2 | 234191399 | + | ENST00000372075 | WAPAL | chr10 | 88206206 | - | 1963 | 971 | 257 | 1429 | 390 |
ENST00000347464 | ATG16L1 | chr2 | 234191399 | + | ENST00000263070 | WAPAL | chr10 | 88206206 | - | 1960 | 971 | 257 | 1429 | 390 |
ENST00000392017 | ATG16L1 | chr2 | 234191399 | + | ENST00000298767 | WAPAL | chr10 | 88206206 | - | 4206 | 1460 | 257 | 1918 | 553 |
ENST00000392017 | ATG16L1 | chr2 | 234191399 | + | ENST00000372075 | WAPAL | chr10 | 88206206 | - | 2452 | 1460 | 257 | 1918 | 553 |
ENST00000392017 | ATG16L1 | chr2 | 234191399 | + | ENST00000263070 | WAPAL | chr10 | 88206206 | - | 2449 | 1460 | 257 | 1918 | 553 |
ENST00000373525 | ATG16L1 | chr2 | 234191399 | + | ENST00000298767 | WAPAL | chr10 | 88206206 | - | 3568 | 822 | 156 | 1280 | 374 |
ENST00000373525 | ATG16L1 | chr2 | 234191399 | + | ENST00000372075 | WAPAL | chr10 | 88206206 | - | 1814 | 822 | 156 | 1280 | 374 |
ENST00000373525 | ATG16L1 | chr2 | 234191399 | + | ENST00000263070 | WAPAL | chr10 | 88206206 | - | 1811 | 822 | 156 | 1280 | 374 |
ENST00000392020 | ATG16L1 | chr2 | 234191399 | + | ENST00000298767 | WAPAL | chr10 | 88206206 | - | 4014 | 1268 | 122 | 1726 | 534 |
ENST00000392020 | ATG16L1 | chr2 | 234191399 | + | ENST00000372075 | WAPAL | chr10 | 88206206 | - | 2260 | 1268 | 122 | 1726 | 534 |
ENST00000392020 | ATG16L1 | chr2 | 234191399 | + | ENST00000263070 | WAPAL | chr10 | 88206206 | - | 2257 | 1268 | 122 | 1726 | 534 |
ENST00000392018 | ATG16L1 | chr2 | 234191399 | + | ENST00000298767 | WAPAL | chr10 | 88206206 | - | 4114 | 1368 | 114 | 1826 | 570 |
ENST00000392018 | ATG16L1 | chr2 | 234191399 | + | ENST00000372075 | WAPAL | chr10 | 88206206 | - | 2360 | 1368 | 114 | 1826 | 570 |
ENST00000392018 | ATG16L1 | chr2 | 234191399 | + | ENST00000263070 | WAPAL | chr10 | 88206206 | - | 2357 | 1368 | 114 | 1826 | 570 |
DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
ENST00000347464 | ENST00000298767 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - | 0.000217193 | 0.99978286 |
ENST00000347464 | ENST00000372075 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - | 0.001149509 | 0.99885046 |
ENST00000347464 | ENST00000263070 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - | 0.001133871 | 0.9988662 |
ENST00000392017 | ENST00000298767 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - | 0.000466326 | 0.99953365 |
ENST00000392017 | ENST00000372075 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - | 0.004062589 | 0.99593747 |
ENST00000392017 | ENST00000263070 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - | 0.004024206 | 0.9959758 |
ENST00000373525 | ENST00000298767 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - | 0.000258451 | 0.9997415 |
ENST00000373525 | ENST00000372075 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - | 0.001063995 | 0.998936 |
ENST00000373525 | ENST00000263070 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - | 0.001049914 | 0.99895006 |
ENST00000392020 | ENST00000298767 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - | 0.000388336 | 0.9996117 |
ENST00000392020 | ENST00000372075 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - | 0.003169929 | 0.99683005 |
ENST00000392020 | ENST00000263070 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - | 0.003129334 | 0.9968707 |
ENST00000392018 | ENST00000298767 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - | 0.000357177 | 0.99964285 |
ENST00000392018 | ENST00000372075 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - | 0.003268711 | 0.9967313 |
ENST00000392018 | ENST00000263070 | ATG16L1 | chr2 | 234191399 | + | WAPAL | chr10 | 88206206 | - | 0.003234581 | 0.9967654 |
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Fusion Genomic Features for ATG16L1-WAPAL |
FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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Fusion Protein Features for ATG16L1-WAPAL |
Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:234191399/chr10:88206206) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
Main function of each fusion partner protein. (from UniProt) |
Hgene | Tgene |
. | . |
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000347464 | + | 8 | 14 | 78_230 | 238 | 445.0 | Coiled coil | Ontology_term=ECO:0000255 |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000392017 | + | 12 | 18 | 78_230 | 401 | 608.0 | Coiled coil | Ontology_term=ECO:0000255 |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000392020 | + | 11 | 17 | 78_230 | 382 | 589.0 | Coiled coil | Ontology_term=ECO:0000255 |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000392017 | + | 12 | 18 | 296_299 | 401 | 608.0 | Motif | Note=Caspase cleavage |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000392020 | + | 11 | 17 | 296_299 | 382 | 589.0 | Motif | Note=Caspase cleavage |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000347464 | + | 8 | 14 | 207_230 | 238 | 445.0 | Region | WIPI2-binding |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000392017 | + | 12 | 18 | 207_230 | 401 | 608.0 | Region | WIPI2-binding |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000392017 | + | 12 | 18 | 230_242 | 401 | 608.0 | Region | RB1CC1-binding |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000392020 | + | 11 | 17 | 207_230 | 382 | 589.0 | Region | WIPI2-binding |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000392020 | + | 11 | 17 | 230_242 | 382 | 589.0 | Region | RB1CC1-binding |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000392017 | + | 12 | 18 | 320_359 | 401 | 608.0 | Repeat | WD 1 |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000392017 | + | 12 | 18 | 364_403 | 401 | 608.0 | Repeat | WD 2 |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000392020 | + | 11 | 17 | 320_359 | 382 | 589.0 | Repeat | WD 1 |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000373525 | + | 9 | 15 | 78_230 | 222 | 429.0 | Coiled coil | Ontology_term=ECO:0000255 |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000347464 | + | 8 | 14 | 296_299 | 238 | 445.0 | Motif | Note=Caspase cleavage |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000373525 | + | 9 | 15 | 296_299 | 222 | 429.0 | Motif | Note=Caspase cleavage |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000347464 | + | 8 | 14 | 230_242 | 238 | 445.0 | Region | RB1CC1-binding |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000373525 | + | 9 | 15 | 207_230 | 222 | 429.0 | Region | WIPI2-binding |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000373525 | + | 9 | 15 | 230_242 | 222 | 429.0 | Region | RB1CC1-binding |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000347464 | + | 8 | 14 | 320_359 | 238 | 445.0 | Repeat | WD 1 |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000347464 | + | 8 | 14 | 364_403 | 238 | 445.0 | Repeat | WD 2 |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000347464 | + | 8 | 14 | 406_445 | 238 | 445.0 | Repeat | WD 3 |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000347464 | + | 8 | 14 | 447_484 | 238 | 445.0 | Repeat | WD 4 |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000347464 | + | 8 | 14 | 486_525 | 238 | 445.0 | Repeat | WD 5 |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000347464 | + | 8 | 14 | 532_573 | 238 | 445.0 | Repeat | WD 6 |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000347464 | + | 8 | 14 | 575_607 | 238 | 445.0 | Repeat | WD 7 |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000373525 | + | 9 | 15 | 320_359 | 222 | 429.0 | Repeat | WD 1 |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000373525 | + | 9 | 15 | 364_403 | 222 | 429.0 | Repeat | WD 2 |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000373525 | + | 9 | 15 | 406_445 | 222 | 429.0 | Repeat | WD 3 |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000373525 | + | 9 | 15 | 447_484 | 222 | 429.0 | Repeat | WD 4 |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000373525 | + | 9 | 15 | 486_525 | 222 | 429.0 | Repeat | WD 5 |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000373525 | + | 9 | 15 | 532_573 | 222 | 429.0 | Repeat | WD 6 |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000373525 | + | 9 | 15 | 575_607 | 222 | 429.0 | Repeat | WD 7 |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000392017 | + | 12 | 18 | 406_445 | 401 | 608.0 | Repeat | WD 3 |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000392017 | + | 12 | 18 | 447_484 | 401 | 608.0 | Repeat | WD 4 |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000392017 | + | 12 | 18 | 486_525 | 401 | 608.0 | Repeat | WD 5 |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000392017 | + | 12 | 18 | 532_573 | 401 | 608.0 | Repeat | WD 6 |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000392017 | + | 12 | 18 | 575_607 | 401 | 608.0 | Repeat | WD 7 |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000392020 | + | 11 | 17 | 364_403 | 382 | 589.0 | Repeat | WD 2 |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000392020 | + | 11 | 17 | 406_445 | 382 | 589.0 | Repeat | WD 3 |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000392020 | + | 11 | 17 | 447_484 | 382 | 589.0 | Repeat | WD 4 |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000392020 | + | 11 | 17 | 486_525 | 382 | 589.0 | Repeat | WD 5 |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000392020 | + | 11 | 17 | 532_573 | 382 | 589.0 | Repeat | WD 6 |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000392020 | + | 11 | 17 | 575_607 | 382 | 589.0 | Repeat | WD 7 |
Tgene | WAPAL | chr2:234191399 | chr10:88206206 | ENST00000298767 | 14 | 19 | 260_286 | 1038 | 1191.0 | Coiled coil | Ontology_term=ECO:0000255 | |
Tgene | WAPAL | chr2:234191399 | chr10:88206206 | ENST00000298767 | 14 | 19 | 749_782 | 1038 | 1191.0 | Coiled coil | Ontology_term=ECO:0000255 | |
Tgene | WAPAL | chr2:234191399 | chr10:88206206 | ENST00000298767 | 14 | 19 | 626_1169 | 1038 | 1191.0 | Domain | WAPL |
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Fusion Gene Sequence for ATG16L1-WAPAL |
For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
>7537_7537_1_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000347464_WAPAL_chr10_88206206_ENST00000263070_length(transcript)=1960nt_BP=971nt ACTAGCGAGCGCCCTGCGTAGGCACCGGCTCCTGAGCCCGTGCTTCGGGTGAGGGGGCGGGTCTTCCGGCCCTCTCGAAAATCATTTCCG GCATGAGCCGGAAGACCGTCCCGGATGGCCTCGGGGACTGCCAGTGTGTGGAGGTGAGCTCCGGGATTGCCGGCATTCCCGCTTCTGCTG GTTGCTTCATGCTGCAGGCTGCGGCCGTCAGCCCTCGCTCGCATTGGTGGCGCTGAGGTGCCGGGGCAGCAAGTGACATGTCGTCGGGCC TCCGCGCCGCTGACTTCCCCCGCTGGAAGCGCCACATCTCGGAGCAACTGAGGCGCCGGGACCGGCTGCAGAGACAGGCGTTCGAGGAGA TCATCCTGCAGTATAACAAATTGCTGGAAAAGTCAGATCTTCATTCAGTGTTGGCCCAGAAACTACAGGCTGAAAAGCATGACGTACCAA ACAGGCACGAGATAAGGAGGCGGCAAGCCCGGCTGCAGAAAGAGCTTGCAGAAGCAGCAAAGGAACCTCTACCAGTCGAACAGGATGATG ACATTGAGGTCATTGTGGATGAAACTTCTGATCACACAGAAGAGACCTCTCCTGTGCGAGCCATCAGCAGAGCAGCCACGAGACGCTCTG TCTCTTCCTTCCCAGTCCCCCAGGACAATGTGGATACTCATCCTGGTTCTGGTAAAGAAGTGAGGGTACCAGCTACTGCCTTGTGTGTCT TCGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCCGGTTACTGGCCACTGGAGGCATGGACCGCAGGGTTAAGC TTTGGGAAGTATTTGGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCAGTAATGCAGGAATTACAAGCATTGAATTTGATAGTGCTG GATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGATGATTATCGATTACGGCTATTCCTTGAGCGAGAGC GGGCAGCCCAGCTAGCAGAAAGTAAAACAGATGAGTTGATCAAAGATGCTCCCACCACTCAGCATGATAAGAGTGGAGAGTGGCAAGAAA CAAGTGGAGAAATACAGTGGGTGTCAACTGAAAAGACTGATGGTACAGAAGAGAAACATAAGAAGGAGGAGGAGGATGAAGAACTTGACC TCAATAAAGCCCTTCAGCATGCCGGCAAACACATGGAGGATTGCATTGTGGCCTCCTACACAGCACTACTTCTTGGGTGTCTCTGCCAGG AAAGTCCAATCAATGTAACCACTGTGCGGGAATATCTGCCAGAAGGAGACTTTTCAATAATGACAGAGATGCTCAAAAAATTTTTGAGTT TTATGAATCTCACTTGTGCTGTTGGAACAACTGGCCAGAAATCTATCTCTAGAGTGATTGAATATTTGGAACATTGCTAGCTGCTTTACC TTTGCTTCAGGTGCTCGGTAATGCTGGAGCTATCCTTAGACAAAGAAAAGTCAAGTCATGAAAGAAGTCCTTGAAGATATACCAAGAACA TTCATCAGTATCATTCGTGTTTGGATTTTTAAGGCCACCTGATTTCTTCGTCATGCATTCGGCATTTGCTAAATGACAGTTACTACATCA ATCTGCAACTATCAAAAATGAGGGGAAAAGGTTCAGGCTGTTAACAATTCCATGCAGTATTTAAATACATTTACTTTGGCAGAGTTTATA CCCTCCCCTTGTTTTCTTGCTTTATTCTGGGCAAGTTTGAAGGGGAAAATTTGTGCTGCTGTTAGTGCAACTGCTGTGTATGTTGAGCCA CTGTTGTCATGCCAGCCAGGTGCAAAGGCAGCTTAGCTACTGAGGTAGCGAATGTTCTGAGGACATTCTAGACAACAGCTTAGTTCCTTT >7537_7537_1_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000347464_WAPAL_chr10_88206206_ENST00000263070_length(amino acids)=390AA_BP=238 MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEIRRRQARLQKELAEAAKEPLPV EQDDDIEVIVDETSDHTEETSPVRAISRAATRRSVSSFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMD RRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRLFLERERAAQLAESKTDELIKDAPTTQHDKSG EWQETSGEIQWVSTEKTDGTEEKHKKEEEDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQESPINVTTVREYLPEGDFSIMTEMLK -------------------------------------------------------------- >7537_7537_2_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000347464_WAPAL_chr10_88206206_ENST00000298767_length(transcript)=3717nt_BP=971nt ACTAGCGAGCGCCCTGCGTAGGCACCGGCTCCTGAGCCCGTGCTTCGGGTGAGGGGGCGGGTCTTCCGGCCCTCTCGAAAATCATTTCCG GCATGAGCCGGAAGACCGTCCCGGATGGCCTCGGGGACTGCCAGTGTGTGGAGGTGAGCTCCGGGATTGCCGGCATTCCCGCTTCTGCTG GTTGCTTCATGCTGCAGGCTGCGGCCGTCAGCCCTCGCTCGCATTGGTGGCGCTGAGGTGCCGGGGCAGCAAGTGACATGTCGTCGGGCC TCCGCGCCGCTGACTTCCCCCGCTGGAAGCGCCACATCTCGGAGCAACTGAGGCGCCGGGACCGGCTGCAGAGACAGGCGTTCGAGGAGA TCATCCTGCAGTATAACAAATTGCTGGAAAAGTCAGATCTTCATTCAGTGTTGGCCCAGAAACTACAGGCTGAAAAGCATGACGTACCAA ACAGGCACGAGATAAGGAGGCGGCAAGCCCGGCTGCAGAAAGAGCTTGCAGAAGCAGCAAAGGAACCTCTACCAGTCGAACAGGATGATG ACATTGAGGTCATTGTGGATGAAACTTCTGATCACACAGAAGAGACCTCTCCTGTGCGAGCCATCAGCAGAGCAGCCACGAGACGCTCTG TCTCTTCCTTCCCAGTCCCCCAGGACAATGTGGATACTCATCCTGGTTCTGGTAAAGAAGTGAGGGTACCAGCTACTGCCTTGTGTGTCT TCGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCCGGTTACTGGCCACTGGAGGCATGGACCGCAGGGTTAAGC TTTGGGAAGTATTTGGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCAGTAATGCAGGAATTACAAGCATTGAATTTGATAGTGCTG GATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGATGATTATCGATTACGGCTATTCCTTGAGCGAGAGC GGGCAGCCCAGCTAGCAGAAAGTAAAACAGATGAGTTGATCAAAGATGCTCCCACCACTCAGCATGATAAGAGTGGAGAGTGGCAAGAAA CAAGTGGAGAAATACAGTGGGTGTCAACTGAAAAGACTGATGGTACAGAAGAGAAACATAAGAAGGAGGAGGAGGATGAAGAACTTGACC TCAATAAAGCCCTTCAGCATGCCGGCAAACACATGGAGGATTGCATTGTGGCCTCCTACACAGCACTACTTCTTGGGTGTCTCTGCCAGG AAAGTCCAATCAATGTAACCACTGTGCGGGAATATCTGCCAGAAGGAGACTTTTCAATAATGACAGAGATGCTCAAAAAATTTTTGAGTT TTATGAATCTCACTTGTGCTGTTGGAACAACTGGCCAGAAATCTATCTCTAGAGTGATTGAATATTTGGAACATTGCTAGCTGCTTTACC TTTGCTTCAGGTGCTCGGTAATGCTGGAGCTATCCTTAGACAAAGAAAAGTCAAGTCATGAAAGAAGTCCTTGAAGATATACCAAGAACA TTCATCAGTATCATTCGTGTTTGGATTTTTAAGGCCACCTGATTTCTTCGTCATGCATTCGGCATTTGCTAAATGACAGTTACTACATCA ATCTGCAACTATCAAAAATGAGGGGAAAAGGTTCAGGCTGTTAACAATTCCATGCAGTATTTAAATACATTTACTTTGGCAGAGTTTATA CCCTCCCCTTGTTTTCTTGCTTTATTCTGGGCAAGTTTGAAGGGGAAAATTTGTGCTGCTGTTAGTGCAACTGCTGTGTATGTTGAGCCA CTGTTGTCATGCCAGCCAGGTGCAAAGGCAGCTTAGCTACTGAGGTAGCGAATGTTCTGAGGACATTCTAGACAACAGCTTAGTTCCTTT TTCAGGCTCATTTGCTTTTGCTTTTTTGTTGAATGATTCCAATCGTAAATAAAGCTTTTAATAATTTTGTGAATTTTTTGGTTGTTGTTC CCTGAACTACTGTCTATATTTAAAATTAGATGGAATCCAAAGATACACGGGATTAATAGTATATTTTTTTATTCTTGATTAGGTTTGGGT TATTGAACTATTTTTTACTTTTGAGACCACAACCATATTCAATATCATACCATAATGTGTCATAGCTATAGGCACAAGAAAAACAACAGT TTGAGAGAATATTATATAAGATGATGTGCCCTGTTAAAAGGAGGAGGCAAAATAGTCAAACCCAGGGTAGTTTACACTTAATGCTAGGGA GGCTCTTAAAACATTATTAGATTTTGAGGAAAGACTCTCTAGATATATTTTCTAATGTTCAGTACAATAAATATAAGGAAGCTAAAACAC CAATGTGGAATTCCTGTTTCCAGATAACATGTATATTCTTCTATAGAGTGACAGGATCAATTGCATAAGCGCAAAGCCTTAAATTGCTGG TTTAGAGAAGACCCTTTTTTCATTCAGATTCTTTGTTCGTAGAGCAGTTATTTGAAAAACAGTTATGGAACACAAAACATTTTATAGATT TAATATCATAACATTGCAAATTTTTCTTGTATTATTCACACCACTGGTTATACTTTTTTTTTTCCTTTTTTATTGATTGGGCCTGAATAC AGGCTTTCTAGAGATCTTTTTCATTAATACTTTTAAATACCTTTCAGGTAGTTACATCATGTTTCTTCATTGGATTTGTAAAACTTGAAG CCATAAAAATATTAGTTTGGTGTGTATTGGGGAAAATAGCTAAAAGTCTAATTTTTACCCATTTAGACTTTGTTATTTCCTTGTATAAAG TGACAAATCGGGGCTCTTGTATCAGTGCCAGCTGTAATGTTTTTAAATGCAGTGGCTGCCTTCTATTGTCTTCCTATTTTTGATAATGCA GATTGTTGGGAAATCTGTAAGGAAGTAACTGATTCCAGGCAAATTGTTTTCTTCCTTCTACCCACCCCAACCCCTACCCATCACCTTTTA AGAACATAGTACGCCAGTGTAACGTGGGAACCATTGAGATTGTATTTGCCCTGAGTATTAAAGCTAGCTTAGCAAAATACTTTTAAAAAC ATATTGGTAAATGATACCCGTAAAATTAAATTAGTTATATTTTATTTTAAAATGCAAAATACATTGATATTTATTAATCATTGGATTTAG GGAAAGGGACAGATTTTTGGTGAACCTGACTTGTGGCAGATGGTAAGGAATATTATAAAACATTTGGATGAGAACAATCAGGGCGAACTG CATTTTTCTGTTACACTGGTAATCATTTGAAAATTGATTTACCTCAGTGTTTAACAGTTTTTTGTTTTGTTTTGTTTTTTAAATAATAAC TAATTGTCGAGCACTGATAGAGATGCAGATTTTGGTGGGGGGAGGTGGTGGGGGAGATAATCACTTCACCAACTGCAGTGCATTTGTGTG TTTTTAACCCTCAGAGAACTCTGCATTTTAGGGTACTTGAGGCTGACTTAACTAAAAGTTTTAAAGTAACCTTTTTTCCATTGTAAATAT TTCTGTAAATACTACCAATTGGAAATTAGAACAGTAGAGTACTTTTCTGAATCCAATCCTATTTTTATTTTATACAGTATTTCTCAGCTG TGATCTTTGGAGCAAAAGCCAACGGCAGGAAAAAATAGTTTGTACCAGTTTCATGAAGTATGTCTTTGGGTTTTTGTAAATAATTTTAAC >7537_7537_2_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000347464_WAPAL_chr10_88206206_ENST00000298767_length(amino acids)=390AA_BP=238 MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEIRRRQARLQKELAEAAKEPLPV EQDDDIEVIVDETSDHTEETSPVRAISRAATRRSVSSFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMD RRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRLFLERERAAQLAESKTDELIKDAPTTQHDKSG EWQETSGEIQWVSTEKTDGTEEKHKKEEEDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQESPINVTTVREYLPEGDFSIMTEMLK -------------------------------------------------------------- >7537_7537_3_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000347464_WAPAL_chr10_88206206_ENST00000372075_length(transcript)=1963nt_BP=971nt ACTAGCGAGCGCCCTGCGTAGGCACCGGCTCCTGAGCCCGTGCTTCGGGTGAGGGGGCGGGTCTTCCGGCCCTCTCGAAAATCATTTCCG GCATGAGCCGGAAGACCGTCCCGGATGGCCTCGGGGACTGCCAGTGTGTGGAGGTGAGCTCCGGGATTGCCGGCATTCCCGCTTCTGCTG GTTGCTTCATGCTGCAGGCTGCGGCCGTCAGCCCTCGCTCGCATTGGTGGCGCTGAGGTGCCGGGGCAGCAAGTGACATGTCGTCGGGCC TCCGCGCCGCTGACTTCCCCCGCTGGAAGCGCCACATCTCGGAGCAACTGAGGCGCCGGGACCGGCTGCAGAGACAGGCGTTCGAGGAGA TCATCCTGCAGTATAACAAATTGCTGGAAAAGTCAGATCTTCATTCAGTGTTGGCCCAGAAACTACAGGCTGAAAAGCATGACGTACCAA ACAGGCACGAGATAAGGAGGCGGCAAGCCCGGCTGCAGAAAGAGCTTGCAGAAGCAGCAAAGGAACCTCTACCAGTCGAACAGGATGATG ACATTGAGGTCATTGTGGATGAAACTTCTGATCACACAGAAGAGACCTCTCCTGTGCGAGCCATCAGCAGAGCAGCCACGAGACGCTCTG TCTCTTCCTTCCCAGTCCCCCAGGACAATGTGGATACTCATCCTGGTTCTGGTAAAGAAGTGAGGGTACCAGCTACTGCCTTGTGTGTCT TCGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCCGGTTACTGGCCACTGGAGGCATGGACCGCAGGGTTAAGC TTTGGGAAGTATTTGGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCAGTAATGCAGGAATTACAAGCATTGAATTTGATAGTGCTG GATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGATGATTATCGATTACGGCTATTCCTTGAGCGAGAGC GGGCAGCCCAGCTAGCAGAAAGTAAAACAGATGAGTTGATCAAAGATGCTCCCACCACTCAGCATGATAAGAGTGGAGAGTGGCAAGAAA CAAGTGGAGAAATACAGTGGGTGTCAACTGAAAAGACTGATGGTACAGAAGAGAAACATAAGAAGGAGGAGGAGGATGAAGAACTTGACC TCAATAAAGCCCTTCAGCATGCCGGCAAACACATGGAGGATTGCATTGTGGCCTCCTACACAGCACTACTTCTTGGGTGTCTCTGCCAGG AAAGTCCAATCAATGTAACCACTGTGCGGGAATATCTGCCAGAAGGAGACTTTTCAATAATGACAGAGATGCTCAAAAAATTTTTGAGTT TTATGAATCTCACTTGTGCTGTTGGAACAACTGGCCAGAAATCTATCTCTAGAGTGATTGAATATTTGGAACATTGCTAGCTGCTTTACC TTTGCTTCAGGTGCTCGGTAATGCTGGAGCTATCCTTAGACAAAGAAAAGTCAAGTCATGAAAGAAGTCCTTGAAGATATACCAAGAACA TTCATCAGTATCATTCGTGTTTGGATTTTTAAGGCCACCTGATTTCTTCGTCATGCATTCGGCATTTGCTAAATGACAGTTACTACATCA ATCTGCAACTATCAAAAATGAGGGGAAAAGGTTCAGGCTGTTAACAATTCCATGCAGTATTTAAATACATTTACTTTGGCAGAGTTTATA CCCTCCCCTTGTTTTCTTGCTTTATTCTGGGCAAGTTTGAAGGGGAAAATTTGTGCTGCTGTTAGTGCAACTGCTGTGTATGTTGAGCCA CTGTTGTCATGCCAGCCAGGTGCAAAGGCAGCTTAGCTACTGAGGTAGCGAATGTTCTGAGGACATTCTAGACAACAGCTTAGTTCCTTT >7537_7537_3_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000347464_WAPAL_chr10_88206206_ENST00000372075_length(amino acids)=390AA_BP=238 MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEIRRRQARLQKELAEAAKEPLPV EQDDDIEVIVDETSDHTEETSPVRAISRAATRRSVSSFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMD RRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRLFLERERAAQLAESKTDELIKDAPTTQHDKSG EWQETSGEIQWVSTEKTDGTEEKHKKEEEDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQESPINVTTVREYLPEGDFSIMTEMLK -------------------------------------------------------------- >7537_7537_4_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000373525_WAPAL_chr10_88206206_ENST00000263070_length(transcript)=1811nt_BP=822nt AAGACCGTCCCGGATGGCCTCGGGGACTGCCAGTGTGTGGAGGTGAGCTCCGGGATTGCCGGCATTCCCGCTTCTGCTGGTTGCTTCATG CTGCAGGCTGCGGCCGTCAGCCCTCGCTCGCATTGGTGGCGCTGAGGTGCCGGGGCAGCAAGTGACATGTCGTCGGGCCTCCGCGCCGCT GACTTCCCCCGCTGGAAGCGCCACATCTCGGAGCAACTGAGGCGCCGGGACCGGCTGCAGAGACAGGCGTTCGAGGAGATCATCCTGCAG TATAACAAATTGCTGGAAAAGTCAGATCTTCATTCAGTGTTGGCCCAGAAACTACAGGCTGAAAAGCATGACGTACCAAACAGGCACGAG ATAAGGAGGCGGCAAGCCCGGCTGCAGAAAGAGCTTGCAGAAGCAGCAAAGGAACCTCTACCAGTCGAACAGGATGATGACATTGAGGTC ATTGTGGATGAAACTTCTGATCACACAGAAGAGACCTCTCCTGTGCGAGCCATCAGCAGAGCAGCCACTAAGCGACTCTCGCAGCCTGCT GGAGGCCTTCTGGATTCTATCACTAATATCTTTGGGAGACGCTCTGTCTCTTCCTTCCCAGTCCCCCAGGACAATGTGGATACTCATCCT GGTTCTGGTAAAGAAGTGAGGGTACCAGCTACTGCCTTGTGTGTCTTCGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCA GGAATTACAAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGATGAT TATCGATTACGGCTATTCCTTGAGCGAGAGCGGGCAGCCCAGCTAGCAGAAAGTAAAACAGATGAGTTGATCAAAGATGCTCCCACCACT CAGCATGATAAGAGTGGAGAGTGGCAAGAAACAAGTGGAGAAATACAGTGGGTGTCAACTGAAAAGACTGATGGTACAGAAGAGAAACAT AAGAAGGAGGAGGAGGATGAAGAACTTGACCTCAATAAAGCCCTTCAGCATGCCGGCAAACACATGGAGGATTGCATTGTGGCCTCCTAC ACAGCACTACTTCTTGGGTGTCTCTGCCAGGAAAGTCCAATCAATGTAACCACTGTGCGGGAATATCTGCCAGAAGGAGACTTTTCAATA ATGACAGAGATGCTCAAAAAATTTTTGAGTTTTATGAATCTCACTTGTGCTGTTGGAACAACTGGCCAGAAATCTATCTCTAGAGTGATT GAATATTTGGAACATTGCTAGCTGCTTTACCTTTGCTTCAGGTGCTCGGTAATGCTGGAGCTATCCTTAGACAAAGAAAAGTCAAGTCAT GAAAGAAGTCCTTGAAGATATACCAAGAACATTCATCAGTATCATTCGTGTTTGGATTTTTAAGGCCACCTGATTTCTTCGTCATGCATT CGGCATTTGCTAAATGACAGTTACTACATCAATCTGCAACTATCAAAAATGAGGGGAAAAGGTTCAGGCTGTTAACAATTCCATGCAGTA TTTAAATACATTTACTTTGGCAGAGTTTATACCCTCCCCTTGTTTTCTTGCTTTATTCTGGGCAAGTTTGAAGGGGAAAATTTGTGCTGC TGTTAGTGCAACTGCTGTGTATGTTGAGCCACTGTTGTCATGCCAGCCAGGTGCAAAGGCAGCTTAGCTACTGAGGTAGCGAATGTTCTG AGGACATTCTAGACAACAGCTTAGTTCCTTTTTCAGGCTCATTTGCTTTTGCTTTTTTGTTGAATGATTCCAATCGTAAATAAAGCTTTT >7537_7537_4_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000373525_WAPAL_chr10_88206206_ENST00000263070_length(amino acids)=374AA_BP=222 MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEIRRRQARLQKELAEAAKEPLPV EQDDDIEVIVDETSDHTEETSPVRAISRAATKRLSQPAGGLLDSITNIFGRRSVSSFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGE VNAVQFSPGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRLFLERERAAQLAESKTDELIKDAPTTQHDKSGEWQETSGEIQWVSTEK TDGTEEKHKKEEEDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQESPINVTTVREYLPEGDFSIMTEMLKKFLSFMNLTCAVGTTG -------------------------------------------------------------- >7537_7537_5_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000373525_WAPAL_chr10_88206206_ENST00000298767_length(transcript)=3568nt_BP=822nt AAGACCGTCCCGGATGGCCTCGGGGACTGCCAGTGTGTGGAGGTGAGCTCCGGGATTGCCGGCATTCCCGCTTCTGCTGGTTGCTTCATG CTGCAGGCTGCGGCCGTCAGCCCTCGCTCGCATTGGTGGCGCTGAGGTGCCGGGGCAGCAAGTGACATGTCGTCGGGCCTCCGCGCCGCT GACTTCCCCCGCTGGAAGCGCCACATCTCGGAGCAACTGAGGCGCCGGGACCGGCTGCAGAGACAGGCGTTCGAGGAGATCATCCTGCAG TATAACAAATTGCTGGAAAAGTCAGATCTTCATTCAGTGTTGGCCCAGAAACTACAGGCTGAAAAGCATGACGTACCAAACAGGCACGAG ATAAGGAGGCGGCAAGCCCGGCTGCAGAAAGAGCTTGCAGAAGCAGCAAAGGAACCTCTACCAGTCGAACAGGATGATGACATTGAGGTC ATTGTGGATGAAACTTCTGATCACACAGAAGAGACCTCTCCTGTGCGAGCCATCAGCAGAGCAGCCACTAAGCGACTCTCGCAGCCTGCT GGAGGCCTTCTGGATTCTATCACTAATATCTTTGGGAGACGCTCTGTCTCTTCCTTCCCAGTCCCCCAGGACAATGTGGATACTCATCCT GGTTCTGGTAAAGAAGTGAGGGTACCAGCTACTGCCTTGTGTGTCTTCGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCA GGAATTACAAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGATGAT TATCGATTACGGCTATTCCTTGAGCGAGAGCGGGCAGCCCAGCTAGCAGAAAGTAAAACAGATGAGTTGATCAAAGATGCTCCCACCACT CAGCATGATAAGAGTGGAGAGTGGCAAGAAACAAGTGGAGAAATACAGTGGGTGTCAACTGAAAAGACTGATGGTACAGAAGAGAAACAT AAGAAGGAGGAGGAGGATGAAGAACTTGACCTCAATAAAGCCCTTCAGCATGCCGGCAAACACATGGAGGATTGCATTGTGGCCTCCTAC ACAGCACTACTTCTTGGGTGTCTCTGCCAGGAAAGTCCAATCAATGTAACCACTGTGCGGGAATATCTGCCAGAAGGAGACTTTTCAATA ATGACAGAGATGCTCAAAAAATTTTTGAGTTTTATGAATCTCACTTGTGCTGTTGGAACAACTGGCCAGAAATCTATCTCTAGAGTGATT GAATATTTGGAACATTGCTAGCTGCTTTACCTTTGCTTCAGGTGCTCGGTAATGCTGGAGCTATCCTTAGACAAAGAAAAGTCAAGTCAT GAAAGAAGTCCTTGAAGATATACCAAGAACATTCATCAGTATCATTCGTGTTTGGATTTTTAAGGCCACCTGATTTCTTCGTCATGCATT CGGCATTTGCTAAATGACAGTTACTACATCAATCTGCAACTATCAAAAATGAGGGGAAAAGGTTCAGGCTGTTAACAATTCCATGCAGTA TTTAAATACATTTACTTTGGCAGAGTTTATACCCTCCCCTTGTTTTCTTGCTTTATTCTGGGCAAGTTTGAAGGGGAAAATTTGTGCTGC TGTTAGTGCAACTGCTGTGTATGTTGAGCCACTGTTGTCATGCCAGCCAGGTGCAAAGGCAGCTTAGCTACTGAGGTAGCGAATGTTCTG AGGACATTCTAGACAACAGCTTAGTTCCTTTTTCAGGCTCATTTGCTTTTGCTTTTTTGTTGAATGATTCCAATCGTAAATAAAGCTTTT AATAATTTTGTGAATTTTTTGGTTGTTGTTCCCTGAACTACTGTCTATATTTAAAATTAGATGGAATCCAAAGATACACGGGATTAATAG TATATTTTTTTATTCTTGATTAGGTTTGGGTTATTGAACTATTTTTTACTTTTGAGACCACAACCATATTCAATATCATACCATAATGTG TCATAGCTATAGGCACAAGAAAAACAACAGTTTGAGAGAATATTATATAAGATGATGTGCCCTGTTAAAAGGAGGAGGCAAAATAGTCAA ACCCAGGGTAGTTTACACTTAATGCTAGGGAGGCTCTTAAAACATTATTAGATTTTGAGGAAAGACTCTCTAGATATATTTTCTAATGTT CAGTACAATAAATATAAGGAAGCTAAAACACCAATGTGGAATTCCTGTTTCCAGATAACATGTATATTCTTCTATAGAGTGACAGGATCA ATTGCATAAGCGCAAAGCCTTAAATTGCTGGTTTAGAGAAGACCCTTTTTTCATTCAGATTCTTTGTTCGTAGAGCAGTTATTTGAAAAA CAGTTATGGAACACAAAACATTTTATAGATTTAATATCATAACATTGCAAATTTTTCTTGTATTATTCACACCACTGGTTATACTTTTTT TTTTCCTTTTTTATTGATTGGGCCTGAATACAGGCTTTCTAGAGATCTTTTTCATTAATACTTTTAAATACCTTTCAGGTAGTTACATCA TGTTTCTTCATTGGATTTGTAAAACTTGAAGCCATAAAAATATTAGTTTGGTGTGTATTGGGGAAAATAGCTAAAAGTCTAATTTTTACC CATTTAGACTTTGTTATTTCCTTGTATAAAGTGACAAATCGGGGCTCTTGTATCAGTGCCAGCTGTAATGTTTTTAAATGCAGTGGCTGC CTTCTATTGTCTTCCTATTTTTGATAATGCAGATTGTTGGGAAATCTGTAAGGAAGTAACTGATTCCAGGCAAATTGTTTTCTTCCTTCT ACCCACCCCAACCCCTACCCATCACCTTTTAAGAACATAGTACGCCAGTGTAACGTGGGAACCATTGAGATTGTATTTGCCCTGAGTATT AAAGCTAGCTTAGCAAAATACTTTTAAAAACATATTGGTAAATGATACCCGTAAAATTAAATTAGTTATATTTTATTTTAAAATGCAAAA TACATTGATATTTATTAATCATTGGATTTAGGGAAAGGGACAGATTTTTGGTGAACCTGACTTGTGGCAGATGGTAAGGAATATTATAAA ACATTTGGATGAGAACAATCAGGGCGAACTGCATTTTTCTGTTACACTGGTAATCATTTGAAAATTGATTTACCTCAGTGTTTAACAGTT TTTTGTTTTGTTTTGTTTTTTAAATAATAACTAATTGTCGAGCACTGATAGAGATGCAGATTTTGGTGGGGGGAGGTGGTGGGGGAGATA ATCACTTCACCAACTGCAGTGCATTTGTGTGTTTTTAACCCTCAGAGAACTCTGCATTTTAGGGTACTTGAGGCTGACTTAACTAAAAGT TTTAAAGTAACCTTTTTTCCATTGTAAATATTTCTGTAAATACTACCAATTGGAAATTAGAACAGTAGAGTACTTTTCTGAATCCAATCC TATTTTTATTTTATACAGTATTTCTCAGCTGTGATCTTTGGAGCAAAAGCCAACGGCAGGAAAAAATAGTTTGTACCAGTTTCATGAAGT >7537_7537_5_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000373525_WAPAL_chr10_88206206_ENST00000298767_length(amino acids)=374AA_BP=222 MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEIRRRQARLQKELAEAAKEPLPV EQDDDIEVIVDETSDHTEETSPVRAISRAATKRLSQPAGGLLDSITNIFGRRSVSSFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGE VNAVQFSPGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRLFLERERAAQLAESKTDELIKDAPTTQHDKSGEWQETSGEIQWVSTEK TDGTEEKHKKEEEDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQESPINVTTVREYLPEGDFSIMTEMLKKFLSFMNLTCAVGTTG -------------------------------------------------------------- >7537_7537_6_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000373525_WAPAL_chr10_88206206_ENST00000372075_length(transcript)=1814nt_BP=822nt AAGACCGTCCCGGATGGCCTCGGGGACTGCCAGTGTGTGGAGGTGAGCTCCGGGATTGCCGGCATTCCCGCTTCTGCTGGTTGCTTCATG CTGCAGGCTGCGGCCGTCAGCCCTCGCTCGCATTGGTGGCGCTGAGGTGCCGGGGCAGCAAGTGACATGTCGTCGGGCCTCCGCGCCGCT GACTTCCCCCGCTGGAAGCGCCACATCTCGGAGCAACTGAGGCGCCGGGACCGGCTGCAGAGACAGGCGTTCGAGGAGATCATCCTGCAG TATAACAAATTGCTGGAAAAGTCAGATCTTCATTCAGTGTTGGCCCAGAAACTACAGGCTGAAAAGCATGACGTACCAAACAGGCACGAG ATAAGGAGGCGGCAAGCCCGGCTGCAGAAAGAGCTTGCAGAAGCAGCAAAGGAACCTCTACCAGTCGAACAGGATGATGACATTGAGGTC ATTGTGGATGAAACTTCTGATCACACAGAAGAGACCTCTCCTGTGCGAGCCATCAGCAGAGCAGCCACTAAGCGACTCTCGCAGCCTGCT GGAGGCCTTCTGGATTCTATCACTAATATCTTTGGGAGACGCTCTGTCTCTTCCTTCCCAGTCCCCCAGGACAATGTGGATACTCATCCT GGTTCTGGTAAAGAAGTGAGGGTACCAGCTACTGCCTTGTGTGTCTTCGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCA GGAATTACAAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGATGAT TATCGATTACGGCTATTCCTTGAGCGAGAGCGGGCAGCCCAGCTAGCAGAAAGTAAAACAGATGAGTTGATCAAAGATGCTCCCACCACT CAGCATGATAAGAGTGGAGAGTGGCAAGAAACAAGTGGAGAAATACAGTGGGTGTCAACTGAAAAGACTGATGGTACAGAAGAGAAACAT AAGAAGGAGGAGGAGGATGAAGAACTTGACCTCAATAAAGCCCTTCAGCATGCCGGCAAACACATGGAGGATTGCATTGTGGCCTCCTAC ACAGCACTACTTCTTGGGTGTCTCTGCCAGGAAAGTCCAATCAATGTAACCACTGTGCGGGAATATCTGCCAGAAGGAGACTTTTCAATA ATGACAGAGATGCTCAAAAAATTTTTGAGTTTTATGAATCTCACTTGTGCTGTTGGAACAACTGGCCAGAAATCTATCTCTAGAGTGATT GAATATTTGGAACATTGCTAGCTGCTTTACCTTTGCTTCAGGTGCTCGGTAATGCTGGAGCTATCCTTAGACAAAGAAAAGTCAAGTCAT GAAAGAAGTCCTTGAAGATATACCAAGAACATTCATCAGTATCATTCGTGTTTGGATTTTTAAGGCCACCTGATTTCTTCGTCATGCATT CGGCATTTGCTAAATGACAGTTACTACATCAATCTGCAACTATCAAAAATGAGGGGAAAAGGTTCAGGCTGTTAACAATTCCATGCAGTA TTTAAATACATTTACTTTGGCAGAGTTTATACCCTCCCCTTGTTTTCTTGCTTTATTCTGGGCAAGTTTGAAGGGGAAAATTTGTGCTGC TGTTAGTGCAACTGCTGTGTATGTTGAGCCACTGTTGTCATGCCAGCCAGGTGCAAAGGCAGCTTAGCTACTGAGGTAGCGAATGTTCTG AGGACATTCTAGACAACAGCTTAGTTCCTTTTTCAGGCTCATTTGCTTTTGCTTTTTTGTTGAATGATTCCAATCGTAAATAAAGCTTTT >7537_7537_6_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000373525_WAPAL_chr10_88206206_ENST00000372075_length(amino acids)=374AA_BP=222 MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEIRRRQARLQKELAEAAKEPLPV EQDDDIEVIVDETSDHTEETSPVRAISRAATKRLSQPAGGLLDSITNIFGRRSVSSFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGE VNAVQFSPGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRLFLERERAAQLAESKTDELIKDAPTTQHDKSGEWQETSGEIQWVSTEK TDGTEEKHKKEEEDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQESPINVTTVREYLPEGDFSIMTEMLKKFLSFMNLTCAVGTTG -------------------------------------------------------------- >7537_7537_7_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000392017_WAPAL_chr10_88206206_ENST00000263070_length(transcript)=2449nt_BP=1460nt ACTAGCGAGCGCCCTGCGTAGGCACCGGCTCCTGAGCCCGTGCTTCGGGTGAGGGGGCGGGTCTTCCGGCCCTCTCGAAAATCATTTCCG GCATGAGCCGGAAGACCGTCCCGGATGGCCTCGGGGACTGCCAGTGTGTGGAGGTGAGCTCCGGGATTGCCGGCATTCCCGCTTCTGCTG GTTGCTTCATGCTGCAGGCTGCGGCCGTCAGCCCTCGCTCGCATTGGTGGCGCTGAGGTGCCGGGGCAGCAAGTGACATGTCGTCGGGCC TCCGCGCCGCTGACTTCCCCCGCTGGAAGCGCCACATCTCGGAGCAACTGAGGCGCCGGGACCGGCTGCAGAGACAGGCGTTCGAGGAGA TCATCCTGCAGTATAACAAATTGCTGGAAAAGTCAGATCTTCATTCAGTGTTGGCCCAGAAACTACAGGCTGAAAAGCATGACGTACCAA ACAGGCACGAGATAAGTCCCGGACATGATGGCACATGGAATGACAATCAGCTACAAGAAATGGCCCAACTGAGGATTAAGCACCAAGAGG AACTGACTGAATTACACAAGAAACGTGGGGAGTTAGCTCAACTGGTGATTGACCTGAATAACCAAATGCAGCGGAAGGACAGGGAGATGC AGATGAATGAAGCAAAAATTGCAGAATGTTTGCAGACTATCTCTGACCTGGAGACGGAGTGCCTAGACCTGCGCACTAAGCTTTGTGACC TTGAAAGAGCCAACCAGACCCTGAAGGATGAATATGATGCCCTGCAGATCACTTTTACTGCCTTGGAGGGAAAACTGAGGAAAACTACGG AAGAGAACCAGGAGCTGGTCACCAGATGGATGGCTGAGAAAGCCCAGGAAGCCAATCGGCTTAATGCAGAGAATGAAAAAGACTCCAGGA GGCGGCAAGCCCGGCTGCAGAAAGAGCTTGCAGAAGCAGCAAAGGAACCTCTACCAGTCGAACAGGATGATGACATTGAGGTCATTGTGG ATGAAACTTCTGATCACACAGAAGAGACCTCTCCTGTGCGAGCCATCAGCAGAGCAGCCACTAAGCGACTCTCGCAGCCTGCTGGAGGCC TTCTGGATTCTATCACTAATATCTTTGGGAGACGCTCTGTCTCTTCCTTCCCAGTCCCCCAGGACAATGTGGATACTCATCCTGGTTCTG GTAAAGAAGTGAGGGTACCAGCTACTGCCTTGTGTGTCTTCGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCC GGTTACTGGCCACTGGAGGCATGGACCGCAGGGTTAAGCTTTGGGAAGTATTTGGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCA GTAATGCAGGAATTACAAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTG TGGATGATTATCGATTACGGCTATTCCTTGAGCGAGAGCGGGCAGCCCAGCTAGCAGAAAGTAAAACAGATGAGTTGATCAAAGATGCTC CCACCACTCAGCATGATAAGAGTGGAGAGTGGCAAGAAACAAGTGGAGAAATACAGTGGGTGTCAACTGAAAAGACTGATGGTACAGAAG AGAAACATAAGAAGGAGGAGGAGGATGAAGAACTTGACCTCAATAAAGCCCTTCAGCATGCCGGCAAACACATGGAGGATTGCATTGTGG CCTCCTACACAGCACTACTTCTTGGGTGTCTCTGCCAGGAAAGTCCAATCAATGTAACCACTGTGCGGGAATATCTGCCAGAAGGAGACT TTTCAATAATGACAGAGATGCTCAAAAAATTTTTGAGTTTTATGAATCTCACTTGTGCTGTTGGAACAACTGGCCAGAAATCTATCTCTA GAGTGATTGAATATTTGGAACATTGCTAGCTGCTTTACCTTTGCTTCAGGTGCTCGGTAATGCTGGAGCTATCCTTAGACAAAGAAAAGT CAAGTCATGAAAGAAGTCCTTGAAGATATACCAAGAACATTCATCAGTATCATTCGTGTTTGGATTTTTAAGGCCACCTGATTTCTTCGT CATGCATTCGGCATTTGCTAAATGACAGTTACTACATCAATCTGCAACTATCAAAAATGAGGGGAAAAGGTTCAGGCTGTTAACAATTCC ATGCAGTATTTAAATACATTTACTTTGGCAGAGTTTATACCCTCCCCTTGTTTTCTTGCTTTATTCTGGGCAAGTTTGAAGGGGAAAATT TGTGCTGCTGTTAGTGCAACTGCTGTGTATGTTGAGCCACTGTTGTCATGCCAGCCAGGTGCAAAGGCAGCTTAGCTACTGAGGTAGCGA ATGTTCTGAGGACATTCTAGACAACAGCTTAGTTCCTTTTTCAGGCTCATTTGCTTTTGCTTTTTTGTTGAATGATTCCAATCGTAAATA >7537_7537_7_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000392017_WAPAL_chr10_88206206_ENST00000263070_length(amino acids)=553AA_BP=401 MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEISPGHDGTWNDNQLQEMAQLRI KHQEELTELHKKRGELAQLVIDLNNQMQRKDREMQMNEAKIAECLQTISDLETECLDLRTKLCDLERANQTLKDEYDALQITFTALEGKL RKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAISRAATKRLSQ PAGGLLDSITNIFGRRSVSSFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKG SLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRLFLERERAAQLAESKTDELIKDAPTTQHDKSGEWQETSGEIQWVSTEKT DGTEEKHKKEEEDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQESPINVTTVREYLPEGDFSIMTEMLKKFLSFMNLTCAVGTTGQ -------------------------------------------------------------- >7537_7537_8_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000392017_WAPAL_chr10_88206206_ENST00000298767_length(transcript)=4206nt_BP=1460nt ACTAGCGAGCGCCCTGCGTAGGCACCGGCTCCTGAGCCCGTGCTTCGGGTGAGGGGGCGGGTCTTCCGGCCCTCTCGAAAATCATTTCCG GCATGAGCCGGAAGACCGTCCCGGATGGCCTCGGGGACTGCCAGTGTGTGGAGGTGAGCTCCGGGATTGCCGGCATTCCCGCTTCTGCTG GTTGCTTCATGCTGCAGGCTGCGGCCGTCAGCCCTCGCTCGCATTGGTGGCGCTGAGGTGCCGGGGCAGCAAGTGACATGTCGTCGGGCC TCCGCGCCGCTGACTTCCCCCGCTGGAAGCGCCACATCTCGGAGCAACTGAGGCGCCGGGACCGGCTGCAGAGACAGGCGTTCGAGGAGA TCATCCTGCAGTATAACAAATTGCTGGAAAAGTCAGATCTTCATTCAGTGTTGGCCCAGAAACTACAGGCTGAAAAGCATGACGTACCAA ACAGGCACGAGATAAGTCCCGGACATGATGGCACATGGAATGACAATCAGCTACAAGAAATGGCCCAACTGAGGATTAAGCACCAAGAGG AACTGACTGAATTACACAAGAAACGTGGGGAGTTAGCTCAACTGGTGATTGACCTGAATAACCAAATGCAGCGGAAGGACAGGGAGATGC AGATGAATGAAGCAAAAATTGCAGAATGTTTGCAGACTATCTCTGACCTGGAGACGGAGTGCCTAGACCTGCGCACTAAGCTTTGTGACC TTGAAAGAGCCAACCAGACCCTGAAGGATGAATATGATGCCCTGCAGATCACTTTTACTGCCTTGGAGGGAAAACTGAGGAAAACTACGG AAGAGAACCAGGAGCTGGTCACCAGATGGATGGCTGAGAAAGCCCAGGAAGCCAATCGGCTTAATGCAGAGAATGAAAAAGACTCCAGGA GGCGGCAAGCCCGGCTGCAGAAAGAGCTTGCAGAAGCAGCAAAGGAACCTCTACCAGTCGAACAGGATGATGACATTGAGGTCATTGTGG ATGAAACTTCTGATCACACAGAAGAGACCTCTCCTGTGCGAGCCATCAGCAGAGCAGCCACTAAGCGACTCTCGCAGCCTGCTGGAGGCC TTCTGGATTCTATCACTAATATCTTTGGGAGACGCTCTGTCTCTTCCTTCCCAGTCCCCCAGGACAATGTGGATACTCATCCTGGTTCTG GTAAAGAAGTGAGGGTACCAGCTACTGCCTTGTGTGTCTTCGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCC GGTTACTGGCCACTGGAGGCATGGACCGCAGGGTTAAGCTTTGGGAAGTATTTGGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCA GTAATGCAGGAATTACAAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTG TGGATGATTATCGATTACGGCTATTCCTTGAGCGAGAGCGGGCAGCCCAGCTAGCAGAAAGTAAAACAGATGAGTTGATCAAAGATGCTC CCACCACTCAGCATGATAAGAGTGGAGAGTGGCAAGAAACAAGTGGAGAAATACAGTGGGTGTCAACTGAAAAGACTGATGGTACAGAAG AGAAACATAAGAAGGAGGAGGAGGATGAAGAACTTGACCTCAATAAAGCCCTTCAGCATGCCGGCAAACACATGGAGGATTGCATTGTGG CCTCCTACACAGCACTACTTCTTGGGTGTCTCTGCCAGGAAAGTCCAATCAATGTAACCACTGTGCGGGAATATCTGCCAGAAGGAGACT TTTCAATAATGACAGAGATGCTCAAAAAATTTTTGAGTTTTATGAATCTCACTTGTGCTGTTGGAACAACTGGCCAGAAATCTATCTCTA GAGTGATTGAATATTTGGAACATTGCTAGCTGCTTTACCTTTGCTTCAGGTGCTCGGTAATGCTGGAGCTATCCTTAGACAAAGAAAAGT CAAGTCATGAAAGAAGTCCTTGAAGATATACCAAGAACATTCATCAGTATCATTCGTGTTTGGATTTTTAAGGCCACCTGATTTCTTCGT CATGCATTCGGCATTTGCTAAATGACAGTTACTACATCAATCTGCAACTATCAAAAATGAGGGGAAAAGGTTCAGGCTGTTAACAATTCC ATGCAGTATTTAAATACATTTACTTTGGCAGAGTTTATACCCTCCCCTTGTTTTCTTGCTTTATTCTGGGCAAGTTTGAAGGGGAAAATT TGTGCTGCTGTTAGTGCAACTGCTGTGTATGTTGAGCCACTGTTGTCATGCCAGCCAGGTGCAAAGGCAGCTTAGCTACTGAGGTAGCGA ATGTTCTGAGGACATTCTAGACAACAGCTTAGTTCCTTTTTCAGGCTCATTTGCTTTTGCTTTTTTGTTGAATGATTCCAATCGTAAATA AAGCTTTTAATAATTTTGTGAATTTTTTGGTTGTTGTTCCCTGAACTACTGTCTATATTTAAAATTAGATGGAATCCAAAGATACACGGG ATTAATAGTATATTTTTTTATTCTTGATTAGGTTTGGGTTATTGAACTATTTTTTACTTTTGAGACCACAACCATATTCAATATCATACC ATAATGTGTCATAGCTATAGGCACAAGAAAAACAACAGTTTGAGAGAATATTATATAAGATGATGTGCCCTGTTAAAAGGAGGAGGCAAA ATAGTCAAACCCAGGGTAGTTTACACTTAATGCTAGGGAGGCTCTTAAAACATTATTAGATTTTGAGGAAAGACTCTCTAGATATATTTT CTAATGTTCAGTACAATAAATATAAGGAAGCTAAAACACCAATGTGGAATTCCTGTTTCCAGATAACATGTATATTCTTCTATAGAGTGA CAGGATCAATTGCATAAGCGCAAAGCCTTAAATTGCTGGTTTAGAGAAGACCCTTTTTTCATTCAGATTCTTTGTTCGTAGAGCAGTTAT TTGAAAAACAGTTATGGAACACAAAACATTTTATAGATTTAATATCATAACATTGCAAATTTTTCTTGTATTATTCACACCACTGGTTAT ACTTTTTTTTTTCCTTTTTTATTGATTGGGCCTGAATACAGGCTTTCTAGAGATCTTTTTCATTAATACTTTTAAATACCTTTCAGGTAG TTACATCATGTTTCTTCATTGGATTTGTAAAACTTGAAGCCATAAAAATATTAGTTTGGTGTGTATTGGGGAAAATAGCTAAAAGTCTAA TTTTTACCCATTTAGACTTTGTTATTTCCTTGTATAAAGTGACAAATCGGGGCTCTTGTATCAGTGCCAGCTGTAATGTTTTTAAATGCA GTGGCTGCCTTCTATTGTCTTCCTATTTTTGATAATGCAGATTGTTGGGAAATCTGTAAGGAAGTAACTGATTCCAGGCAAATTGTTTTC TTCCTTCTACCCACCCCAACCCCTACCCATCACCTTTTAAGAACATAGTACGCCAGTGTAACGTGGGAACCATTGAGATTGTATTTGCCC TGAGTATTAAAGCTAGCTTAGCAAAATACTTTTAAAAACATATTGGTAAATGATACCCGTAAAATTAAATTAGTTATATTTTATTTTAAA ATGCAAAATACATTGATATTTATTAATCATTGGATTTAGGGAAAGGGACAGATTTTTGGTGAACCTGACTTGTGGCAGATGGTAAGGAAT ATTATAAAACATTTGGATGAGAACAATCAGGGCGAACTGCATTTTTCTGTTACACTGGTAATCATTTGAAAATTGATTTACCTCAGTGTT TAACAGTTTTTTGTTTTGTTTTGTTTTTTAAATAATAACTAATTGTCGAGCACTGATAGAGATGCAGATTTTGGTGGGGGGAGGTGGTGG GGGAGATAATCACTTCACCAACTGCAGTGCATTTGTGTGTTTTTAACCCTCAGAGAACTCTGCATTTTAGGGTACTTGAGGCTGACTTAA CTAAAAGTTTTAAAGTAACCTTTTTTCCATTGTAAATATTTCTGTAAATACTACCAATTGGAAATTAGAACAGTAGAGTACTTTTCTGAA TCCAATCCTATTTTTATTTTATACAGTATTTCTCAGCTGTGATCTTTGGAGCAAAAGCCAACGGCAGGAAAAAATAGTTTGTACCAGTTT >7537_7537_8_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000392017_WAPAL_chr10_88206206_ENST00000298767_length(amino acids)=553AA_BP=401 MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEISPGHDGTWNDNQLQEMAQLRI KHQEELTELHKKRGELAQLVIDLNNQMQRKDREMQMNEAKIAECLQTISDLETECLDLRTKLCDLERANQTLKDEYDALQITFTALEGKL RKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAISRAATKRLSQ PAGGLLDSITNIFGRRSVSSFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKG SLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRLFLERERAAQLAESKTDELIKDAPTTQHDKSGEWQETSGEIQWVSTEKT DGTEEKHKKEEEDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQESPINVTTVREYLPEGDFSIMTEMLKKFLSFMNLTCAVGTTGQ -------------------------------------------------------------- >7537_7537_9_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000392017_WAPAL_chr10_88206206_ENST00000372075_length(transcript)=2452nt_BP=1460nt ACTAGCGAGCGCCCTGCGTAGGCACCGGCTCCTGAGCCCGTGCTTCGGGTGAGGGGGCGGGTCTTCCGGCCCTCTCGAAAATCATTTCCG GCATGAGCCGGAAGACCGTCCCGGATGGCCTCGGGGACTGCCAGTGTGTGGAGGTGAGCTCCGGGATTGCCGGCATTCCCGCTTCTGCTG GTTGCTTCATGCTGCAGGCTGCGGCCGTCAGCCCTCGCTCGCATTGGTGGCGCTGAGGTGCCGGGGCAGCAAGTGACATGTCGTCGGGCC TCCGCGCCGCTGACTTCCCCCGCTGGAAGCGCCACATCTCGGAGCAACTGAGGCGCCGGGACCGGCTGCAGAGACAGGCGTTCGAGGAGA TCATCCTGCAGTATAACAAATTGCTGGAAAAGTCAGATCTTCATTCAGTGTTGGCCCAGAAACTACAGGCTGAAAAGCATGACGTACCAA ACAGGCACGAGATAAGTCCCGGACATGATGGCACATGGAATGACAATCAGCTACAAGAAATGGCCCAACTGAGGATTAAGCACCAAGAGG AACTGACTGAATTACACAAGAAACGTGGGGAGTTAGCTCAACTGGTGATTGACCTGAATAACCAAATGCAGCGGAAGGACAGGGAGATGC AGATGAATGAAGCAAAAATTGCAGAATGTTTGCAGACTATCTCTGACCTGGAGACGGAGTGCCTAGACCTGCGCACTAAGCTTTGTGACC TTGAAAGAGCCAACCAGACCCTGAAGGATGAATATGATGCCCTGCAGATCACTTTTACTGCCTTGGAGGGAAAACTGAGGAAAACTACGG AAGAGAACCAGGAGCTGGTCACCAGATGGATGGCTGAGAAAGCCCAGGAAGCCAATCGGCTTAATGCAGAGAATGAAAAAGACTCCAGGA GGCGGCAAGCCCGGCTGCAGAAAGAGCTTGCAGAAGCAGCAAAGGAACCTCTACCAGTCGAACAGGATGATGACATTGAGGTCATTGTGG ATGAAACTTCTGATCACACAGAAGAGACCTCTCCTGTGCGAGCCATCAGCAGAGCAGCCACTAAGCGACTCTCGCAGCCTGCTGGAGGCC TTCTGGATTCTATCACTAATATCTTTGGGAGACGCTCTGTCTCTTCCTTCCCAGTCCCCCAGGACAATGTGGATACTCATCCTGGTTCTG GTAAAGAAGTGAGGGTACCAGCTACTGCCTTGTGTGTCTTCGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCC GGTTACTGGCCACTGGAGGCATGGACCGCAGGGTTAAGCTTTGGGAAGTATTTGGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCA GTAATGCAGGAATTACAAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTG TGGATGATTATCGATTACGGCTATTCCTTGAGCGAGAGCGGGCAGCCCAGCTAGCAGAAAGTAAAACAGATGAGTTGATCAAAGATGCTC CCACCACTCAGCATGATAAGAGTGGAGAGTGGCAAGAAACAAGTGGAGAAATACAGTGGGTGTCAACTGAAAAGACTGATGGTACAGAAG AGAAACATAAGAAGGAGGAGGAGGATGAAGAACTTGACCTCAATAAAGCCCTTCAGCATGCCGGCAAACACATGGAGGATTGCATTGTGG CCTCCTACACAGCACTACTTCTTGGGTGTCTCTGCCAGGAAAGTCCAATCAATGTAACCACTGTGCGGGAATATCTGCCAGAAGGAGACT TTTCAATAATGACAGAGATGCTCAAAAAATTTTTGAGTTTTATGAATCTCACTTGTGCTGTTGGAACAACTGGCCAGAAATCTATCTCTA GAGTGATTGAATATTTGGAACATTGCTAGCTGCTTTACCTTTGCTTCAGGTGCTCGGTAATGCTGGAGCTATCCTTAGACAAAGAAAAGT CAAGTCATGAAAGAAGTCCTTGAAGATATACCAAGAACATTCATCAGTATCATTCGTGTTTGGATTTTTAAGGCCACCTGATTTCTTCGT CATGCATTCGGCATTTGCTAAATGACAGTTACTACATCAATCTGCAACTATCAAAAATGAGGGGAAAAGGTTCAGGCTGTTAACAATTCC ATGCAGTATTTAAATACATTTACTTTGGCAGAGTTTATACCCTCCCCTTGTTTTCTTGCTTTATTCTGGGCAAGTTTGAAGGGGAAAATT TGTGCTGCTGTTAGTGCAACTGCTGTGTATGTTGAGCCACTGTTGTCATGCCAGCCAGGTGCAAAGGCAGCTTAGCTACTGAGGTAGCGA ATGTTCTGAGGACATTCTAGACAACAGCTTAGTTCCTTTTTCAGGCTCATTTGCTTTTGCTTTTTTGTTGAATGATTCCAATCGTAAATA >7537_7537_9_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000392017_WAPAL_chr10_88206206_ENST00000372075_length(amino acids)=553AA_BP=401 MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEISPGHDGTWNDNQLQEMAQLRI KHQEELTELHKKRGELAQLVIDLNNQMQRKDREMQMNEAKIAECLQTISDLETECLDLRTKLCDLERANQTLKDEYDALQITFTALEGKL RKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAISRAATKRLSQ PAGGLLDSITNIFGRRSVSSFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKG SLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRLFLERERAAQLAESKTDELIKDAPTTQHDKSGEWQETSGEIQWVSTEKT DGTEEKHKKEEEDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQESPINVTTVREYLPEGDFSIMTEMLKKFLSFMNLTCAVGTTGQ -------------------------------------------------------------- >7537_7537_10_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000392018_WAPAL_chr10_88206206_ENST00000263070_length(transcript)=2357nt_BP=1368nt GTGAGCTCCGGGATTGCCGGCATTCCCGCTTCTGCTGGTTGCTTCATGCTGCAGGCTGCGGCCGTCAGCCCTCGCTCGCATTGGTGGCGC TGAGGTGCCGGGGCAGCAAGTGACATGTCGTCGGGCCTCCGCGCCGCTGACTTCCCCCGCTGGAAGCGCCACATCTCGGAGCAACTGAGG CGCCGGGACCGGCTGCAGAGACAGGCGTTCGAGGAGATCATCCTGCAGTATAACAAATTGCTGGAAAAGTCAGATCTTCATTCAGTGTTG GCCCAGAAACTACAGGCTGAAAAGCATGACGTACCAAACAGGCACGAGATAAGTCCCGGACATGATGGCACATGGAATGACAATCAGCTA CAAGAAATGGCCCAACTGAGGATTAAGCACCAAGAGGAACTGACTGAATTACACAAGAAACGTGGGGAGTTAGCTCAACTGGTGATTGAC CTGAATAACCAAATGCAGCGGAAGGACAGGGAGATGCAGATGAATGAAGCAAAAATTGCAGAATGTTTGCAGACTATCTCTGACCTGGAG ACGGAGTGCCTAGACCTGCGCACTAAGCTTTGTGACCTTGAAAGAGCCAACCAGACCCTGAAGGATGAATATGATGCCCTGCAGATCACT TTTACTGCCTTGGAGGGAAAACTGAGGAAAACTACGGAAGAGAACCAGGAGCTGGTCACCAGATGGATGGCTGAGAAAGCCCAGGAAGCC AATCGGCTTAATGCAGAGAATGAAAAAGACTCCAGGAGGCGGCAAGCCCGGCTGCAGAAAGAGCTTGCAGAAGCAGCAAAGGAACCTCTA CCAGTCGAACAGGATGATGACATTGAGGTCATTGTGGATGAAACTTCTGATCACACAGAAGAGACCTCTCCTGTGCGAGCCATCAGCAGA GCAGCCACTAAGCGACTCTCGCAGCCTGCTGGAGGCCTTCTGGATTCTATCACTAATATCTTTGGTCTGTCCGAGTCTCCCCTTTTGGGA CATCATTCTTCTTCTGATGCTGCCAGGAGACGCTCTGTCTCTTCCTTCCCAGTCCCCCAGGACAATGTGGATACTCATCCTGGTTCTGGT AAAGAAGTGAGGGTACCAGCTACTGCCTTGTGTGTCTTCGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCCGG TTACTGGCCACTGGAGGCATGGACCGCAGGGTTAAGCTTTGGGAAGTATTTGGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCAGT AATGCAGGAATTACAAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTG GATGATTATCGATTACGGCTATTCCTTGAGCGAGAGCGGGCAGCCCAGCTAGCAGAAAGTAAAACAGATGAGTTGATCAAAGATGCTCCC ACCACTCAGCATGATAAGAGTGGAGAGTGGCAAGAAACAAGTGGAGAAATACAGTGGGTGTCAACTGAAAAGACTGATGGTACAGAAGAG AAACATAAGAAGGAGGAGGAGGATGAAGAACTTGACCTCAATAAAGCCCTTCAGCATGCCGGCAAACACATGGAGGATTGCATTGTGGCC TCCTACACAGCACTACTTCTTGGGTGTCTCTGCCAGGAAAGTCCAATCAATGTAACCACTGTGCGGGAATATCTGCCAGAAGGAGACTTT TCAATAATGACAGAGATGCTCAAAAAATTTTTGAGTTTTATGAATCTCACTTGTGCTGTTGGAACAACTGGCCAGAAATCTATCTCTAGA GTGATTGAATATTTGGAACATTGCTAGCTGCTTTACCTTTGCTTCAGGTGCTCGGTAATGCTGGAGCTATCCTTAGACAAAGAAAAGTCA AGTCATGAAAGAAGTCCTTGAAGATATACCAAGAACATTCATCAGTATCATTCGTGTTTGGATTTTTAAGGCCACCTGATTTCTTCGTCA TGCATTCGGCATTTGCTAAATGACAGTTACTACATCAATCTGCAACTATCAAAAATGAGGGGAAAAGGTTCAGGCTGTTAACAATTCCAT GCAGTATTTAAATACATTTACTTTGGCAGAGTTTATACCCTCCCCTTGTTTTCTTGCTTTATTCTGGGCAAGTTTGAAGGGGAAAATTTG TGCTGCTGTTAGTGCAACTGCTGTGTATGTTGAGCCACTGTTGTCATGCCAGCCAGGTGCAAAGGCAGCTTAGCTACTGAGGTAGCGAAT GTTCTGAGGACATTCTAGACAACAGCTTAGTTCCTTTTTCAGGCTCATTTGCTTTTGCTTTTTTGTTGAATGATTCCAATCGTAAATAAA >7537_7537_10_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000392018_WAPAL_chr10_88206206_ENST00000263070_length(amino acids)=570AA_BP=418 MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEISPGHDGTWNDNQLQEMAQLRI KHQEELTELHKKRGELAQLVIDLNNQMQRKDREMQMNEAKIAECLQTISDLETECLDLRTKLCDLERANQTLKDEYDALQITFTALEGKL RKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAISRAATKRLSQ PAGGLLDSITNIFGLSESPLLGHHSSSDAARRRSVSSFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMD RRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRLFLERERAAQLAESKTDELIKDAPTTQHDKSG EWQETSGEIQWVSTEKTDGTEEKHKKEEEDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQESPINVTTVREYLPEGDFSIMTEMLK -------------------------------------------------------------- >7537_7537_11_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000392018_WAPAL_chr10_88206206_ENST00000298767_length(transcript)=4114nt_BP=1368nt GTGAGCTCCGGGATTGCCGGCATTCCCGCTTCTGCTGGTTGCTTCATGCTGCAGGCTGCGGCCGTCAGCCCTCGCTCGCATTGGTGGCGC TGAGGTGCCGGGGCAGCAAGTGACATGTCGTCGGGCCTCCGCGCCGCTGACTTCCCCCGCTGGAAGCGCCACATCTCGGAGCAACTGAGG CGCCGGGACCGGCTGCAGAGACAGGCGTTCGAGGAGATCATCCTGCAGTATAACAAATTGCTGGAAAAGTCAGATCTTCATTCAGTGTTG GCCCAGAAACTACAGGCTGAAAAGCATGACGTACCAAACAGGCACGAGATAAGTCCCGGACATGATGGCACATGGAATGACAATCAGCTA CAAGAAATGGCCCAACTGAGGATTAAGCACCAAGAGGAACTGACTGAATTACACAAGAAACGTGGGGAGTTAGCTCAACTGGTGATTGAC CTGAATAACCAAATGCAGCGGAAGGACAGGGAGATGCAGATGAATGAAGCAAAAATTGCAGAATGTTTGCAGACTATCTCTGACCTGGAG ACGGAGTGCCTAGACCTGCGCACTAAGCTTTGTGACCTTGAAAGAGCCAACCAGACCCTGAAGGATGAATATGATGCCCTGCAGATCACT TTTACTGCCTTGGAGGGAAAACTGAGGAAAACTACGGAAGAGAACCAGGAGCTGGTCACCAGATGGATGGCTGAGAAAGCCCAGGAAGCC AATCGGCTTAATGCAGAGAATGAAAAAGACTCCAGGAGGCGGCAAGCCCGGCTGCAGAAAGAGCTTGCAGAAGCAGCAAAGGAACCTCTA CCAGTCGAACAGGATGATGACATTGAGGTCATTGTGGATGAAACTTCTGATCACACAGAAGAGACCTCTCCTGTGCGAGCCATCAGCAGA GCAGCCACTAAGCGACTCTCGCAGCCTGCTGGAGGCCTTCTGGATTCTATCACTAATATCTTTGGTCTGTCCGAGTCTCCCCTTTTGGGA CATCATTCTTCTTCTGATGCTGCCAGGAGACGCTCTGTCTCTTCCTTCCCAGTCCCCCAGGACAATGTGGATACTCATCCTGGTTCTGGT AAAGAAGTGAGGGTACCAGCTACTGCCTTGTGTGTCTTCGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCCGG TTACTGGCCACTGGAGGCATGGACCGCAGGGTTAAGCTTTGGGAAGTATTTGGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCAGT AATGCAGGAATTACAAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTG GATGATTATCGATTACGGCTATTCCTTGAGCGAGAGCGGGCAGCCCAGCTAGCAGAAAGTAAAACAGATGAGTTGATCAAAGATGCTCCC ACCACTCAGCATGATAAGAGTGGAGAGTGGCAAGAAACAAGTGGAGAAATACAGTGGGTGTCAACTGAAAAGACTGATGGTACAGAAGAG AAACATAAGAAGGAGGAGGAGGATGAAGAACTTGACCTCAATAAAGCCCTTCAGCATGCCGGCAAACACATGGAGGATTGCATTGTGGCC TCCTACACAGCACTACTTCTTGGGTGTCTCTGCCAGGAAAGTCCAATCAATGTAACCACTGTGCGGGAATATCTGCCAGAAGGAGACTTT TCAATAATGACAGAGATGCTCAAAAAATTTTTGAGTTTTATGAATCTCACTTGTGCTGTTGGAACAACTGGCCAGAAATCTATCTCTAGA GTGATTGAATATTTGGAACATTGCTAGCTGCTTTACCTTTGCTTCAGGTGCTCGGTAATGCTGGAGCTATCCTTAGACAAAGAAAAGTCA AGTCATGAAAGAAGTCCTTGAAGATATACCAAGAACATTCATCAGTATCATTCGTGTTTGGATTTTTAAGGCCACCTGATTTCTTCGTCA TGCATTCGGCATTTGCTAAATGACAGTTACTACATCAATCTGCAACTATCAAAAATGAGGGGAAAAGGTTCAGGCTGTTAACAATTCCAT GCAGTATTTAAATACATTTACTTTGGCAGAGTTTATACCCTCCCCTTGTTTTCTTGCTTTATTCTGGGCAAGTTTGAAGGGGAAAATTTG TGCTGCTGTTAGTGCAACTGCTGTGTATGTTGAGCCACTGTTGTCATGCCAGCCAGGTGCAAAGGCAGCTTAGCTACTGAGGTAGCGAAT GTTCTGAGGACATTCTAGACAACAGCTTAGTTCCTTTTTCAGGCTCATTTGCTTTTGCTTTTTTGTTGAATGATTCCAATCGTAAATAAA GCTTTTAATAATTTTGTGAATTTTTTGGTTGTTGTTCCCTGAACTACTGTCTATATTTAAAATTAGATGGAATCCAAAGATACACGGGAT TAATAGTATATTTTTTTATTCTTGATTAGGTTTGGGTTATTGAACTATTTTTTACTTTTGAGACCACAACCATATTCAATATCATACCAT AATGTGTCATAGCTATAGGCACAAGAAAAACAACAGTTTGAGAGAATATTATATAAGATGATGTGCCCTGTTAAAAGGAGGAGGCAAAAT AGTCAAACCCAGGGTAGTTTACACTTAATGCTAGGGAGGCTCTTAAAACATTATTAGATTTTGAGGAAAGACTCTCTAGATATATTTTCT AATGTTCAGTACAATAAATATAAGGAAGCTAAAACACCAATGTGGAATTCCTGTTTCCAGATAACATGTATATTCTTCTATAGAGTGACA GGATCAATTGCATAAGCGCAAAGCCTTAAATTGCTGGTTTAGAGAAGACCCTTTTTTCATTCAGATTCTTTGTTCGTAGAGCAGTTATTT GAAAAACAGTTATGGAACACAAAACATTTTATAGATTTAATATCATAACATTGCAAATTTTTCTTGTATTATTCACACCACTGGTTATAC TTTTTTTTTTCCTTTTTTATTGATTGGGCCTGAATACAGGCTTTCTAGAGATCTTTTTCATTAATACTTTTAAATACCTTTCAGGTAGTT ACATCATGTTTCTTCATTGGATTTGTAAAACTTGAAGCCATAAAAATATTAGTTTGGTGTGTATTGGGGAAAATAGCTAAAAGTCTAATT TTTACCCATTTAGACTTTGTTATTTCCTTGTATAAAGTGACAAATCGGGGCTCTTGTATCAGTGCCAGCTGTAATGTTTTTAAATGCAGT GGCTGCCTTCTATTGTCTTCCTATTTTTGATAATGCAGATTGTTGGGAAATCTGTAAGGAAGTAACTGATTCCAGGCAAATTGTTTTCTT CCTTCTACCCACCCCAACCCCTACCCATCACCTTTTAAGAACATAGTACGCCAGTGTAACGTGGGAACCATTGAGATTGTATTTGCCCTG AGTATTAAAGCTAGCTTAGCAAAATACTTTTAAAAACATATTGGTAAATGATACCCGTAAAATTAAATTAGTTATATTTTATTTTAAAAT GCAAAATACATTGATATTTATTAATCATTGGATTTAGGGAAAGGGACAGATTTTTGGTGAACCTGACTTGTGGCAGATGGTAAGGAATAT TATAAAACATTTGGATGAGAACAATCAGGGCGAACTGCATTTTTCTGTTACACTGGTAATCATTTGAAAATTGATTTACCTCAGTGTTTA ACAGTTTTTTGTTTTGTTTTGTTTTTTAAATAATAACTAATTGTCGAGCACTGATAGAGATGCAGATTTTGGTGGGGGGAGGTGGTGGGG GAGATAATCACTTCACCAACTGCAGTGCATTTGTGTGTTTTTAACCCTCAGAGAACTCTGCATTTTAGGGTACTTGAGGCTGACTTAACT AAAAGTTTTAAAGTAACCTTTTTTCCATTGTAAATATTTCTGTAAATACTACCAATTGGAAATTAGAACAGTAGAGTACTTTTCTGAATC CAATCCTATTTTTATTTTATACAGTATTTCTCAGCTGTGATCTTTGGAGCAAAAGCCAACGGCAGGAAAAAATAGTTTGTACCAGTTTCA >7537_7537_11_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000392018_WAPAL_chr10_88206206_ENST00000298767_length(amino acids)=570AA_BP=418 MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEISPGHDGTWNDNQLQEMAQLRI KHQEELTELHKKRGELAQLVIDLNNQMQRKDREMQMNEAKIAECLQTISDLETECLDLRTKLCDLERANQTLKDEYDALQITFTALEGKL RKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAISRAATKRLSQ PAGGLLDSITNIFGLSESPLLGHHSSSDAARRRSVSSFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMD RRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRLFLERERAAQLAESKTDELIKDAPTTQHDKSG EWQETSGEIQWVSTEKTDGTEEKHKKEEEDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQESPINVTTVREYLPEGDFSIMTEMLK -------------------------------------------------------------- >7537_7537_12_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000392018_WAPAL_chr10_88206206_ENST00000372075_length(transcript)=2360nt_BP=1368nt GTGAGCTCCGGGATTGCCGGCATTCCCGCTTCTGCTGGTTGCTTCATGCTGCAGGCTGCGGCCGTCAGCCCTCGCTCGCATTGGTGGCGC TGAGGTGCCGGGGCAGCAAGTGACATGTCGTCGGGCCTCCGCGCCGCTGACTTCCCCCGCTGGAAGCGCCACATCTCGGAGCAACTGAGG CGCCGGGACCGGCTGCAGAGACAGGCGTTCGAGGAGATCATCCTGCAGTATAACAAATTGCTGGAAAAGTCAGATCTTCATTCAGTGTTG GCCCAGAAACTACAGGCTGAAAAGCATGACGTACCAAACAGGCACGAGATAAGTCCCGGACATGATGGCACATGGAATGACAATCAGCTA CAAGAAATGGCCCAACTGAGGATTAAGCACCAAGAGGAACTGACTGAATTACACAAGAAACGTGGGGAGTTAGCTCAACTGGTGATTGAC CTGAATAACCAAATGCAGCGGAAGGACAGGGAGATGCAGATGAATGAAGCAAAAATTGCAGAATGTTTGCAGACTATCTCTGACCTGGAG ACGGAGTGCCTAGACCTGCGCACTAAGCTTTGTGACCTTGAAAGAGCCAACCAGACCCTGAAGGATGAATATGATGCCCTGCAGATCACT TTTACTGCCTTGGAGGGAAAACTGAGGAAAACTACGGAAGAGAACCAGGAGCTGGTCACCAGATGGATGGCTGAGAAAGCCCAGGAAGCC AATCGGCTTAATGCAGAGAATGAAAAAGACTCCAGGAGGCGGCAAGCCCGGCTGCAGAAAGAGCTTGCAGAAGCAGCAAAGGAACCTCTA CCAGTCGAACAGGATGATGACATTGAGGTCATTGTGGATGAAACTTCTGATCACACAGAAGAGACCTCTCCTGTGCGAGCCATCAGCAGA GCAGCCACTAAGCGACTCTCGCAGCCTGCTGGAGGCCTTCTGGATTCTATCACTAATATCTTTGGTCTGTCCGAGTCTCCCCTTTTGGGA CATCATTCTTCTTCTGATGCTGCCAGGAGACGCTCTGTCTCTTCCTTCCCAGTCCCCCAGGACAATGTGGATACTCATCCTGGTTCTGGT AAAGAAGTGAGGGTACCAGCTACTGCCTTGTGTGTCTTCGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCCGG TTACTGGCCACTGGAGGCATGGACCGCAGGGTTAAGCTTTGGGAAGTATTTGGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCAGT AATGCAGGAATTACAAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTG GATGATTATCGATTACGGCTATTCCTTGAGCGAGAGCGGGCAGCCCAGCTAGCAGAAAGTAAAACAGATGAGTTGATCAAAGATGCTCCC ACCACTCAGCATGATAAGAGTGGAGAGTGGCAAGAAACAAGTGGAGAAATACAGTGGGTGTCAACTGAAAAGACTGATGGTACAGAAGAG AAACATAAGAAGGAGGAGGAGGATGAAGAACTTGACCTCAATAAAGCCCTTCAGCATGCCGGCAAACACATGGAGGATTGCATTGTGGCC TCCTACACAGCACTACTTCTTGGGTGTCTCTGCCAGGAAAGTCCAATCAATGTAACCACTGTGCGGGAATATCTGCCAGAAGGAGACTTT TCAATAATGACAGAGATGCTCAAAAAATTTTTGAGTTTTATGAATCTCACTTGTGCTGTTGGAACAACTGGCCAGAAATCTATCTCTAGA GTGATTGAATATTTGGAACATTGCTAGCTGCTTTACCTTTGCTTCAGGTGCTCGGTAATGCTGGAGCTATCCTTAGACAAAGAAAAGTCA AGTCATGAAAGAAGTCCTTGAAGATATACCAAGAACATTCATCAGTATCATTCGTGTTTGGATTTTTAAGGCCACCTGATTTCTTCGTCA TGCATTCGGCATTTGCTAAATGACAGTTACTACATCAATCTGCAACTATCAAAAATGAGGGGAAAAGGTTCAGGCTGTTAACAATTCCAT GCAGTATTTAAATACATTTACTTTGGCAGAGTTTATACCCTCCCCTTGTTTTCTTGCTTTATTCTGGGCAAGTTTGAAGGGGAAAATTTG TGCTGCTGTTAGTGCAACTGCTGTGTATGTTGAGCCACTGTTGTCATGCCAGCCAGGTGCAAAGGCAGCTTAGCTACTGAGGTAGCGAAT GTTCTGAGGACATTCTAGACAACAGCTTAGTTCCTTTTTCAGGCTCATTTGCTTTTGCTTTTTTGTTGAATGATTCCAATCGTAAATAAA >7537_7537_12_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000392018_WAPAL_chr10_88206206_ENST00000372075_length(amino acids)=570AA_BP=418 MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEISPGHDGTWNDNQLQEMAQLRI KHQEELTELHKKRGELAQLVIDLNNQMQRKDREMQMNEAKIAECLQTISDLETECLDLRTKLCDLERANQTLKDEYDALQITFTALEGKL RKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAISRAATKRLSQ PAGGLLDSITNIFGLSESPLLGHHSSSDAARRRSVSSFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMD RRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRLFLERERAAQLAESKTDELIKDAPTTQHDKSG EWQETSGEIQWVSTEKTDGTEEKHKKEEEDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQESPINVTTVREYLPEGDFSIMTEMLK -------------------------------------------------------------- >7537_7537_13_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000392020_WAPAL_chr10_88206206_ENST00000263070_length(transcript)=2257nt_BP=1268nt GTGTGGAGGTGAGCTCCGGGATTGCCGGCATTCCCGCTTCTGCTGGTTGCTTCATGCTGCAGGCTGCGGCCGTCAGCCCTCGCTCGCATT GGTGGCGCTGAGGTGCCGGGGCAGCAAGTGACATGTCGTCGGGCCTCCGCGCCGCTGACTTCCCCCGCTGGAAGCGCCACATCTCGGAGC AACTGAGGCGCCGGGACCGGCTGCAGAGACAGGCGTTCGAGGAGATCATCCTGCAGTATAACAAATTGCTGGAAAAGTCAGATCTTCATT CAGTGTTGGCCCAGAAACTACAGGCTGAAAAGCATGACGTACCAAACAGGCACGAGATAAGTCCCGGACATGATGGCACATGGAATGACA ATCAGCTACAAGAAATGGCCCAACTGAGGATTAAGCACCAAGAGGAACTGACTGAATTACACAAGAAACGTGGGGAGTTAGCTCAACTGG TGATTGACCTGAATAACCAAATGCAGCGGAAGGACAGGGAGATGCAGATGAATGAAGCAAAAATTGCAGAATGTTTGCAGACTATCTCTG ACCTGGAGACGGAGTGCCTAGACCTGCGCACTAAGCTTTGTGACCTTGAAAGAGCCAACCAGACCCTGAAGGATGAATATGATGCCCTGC AGATCACTTTTACTGCCTTGGAGGGAAAACTGAGGAAAACTACGGAAGAGAACCAGGAGCTGGTCACCAGATGGATGGCTGAGAAAGCCC AGGAAGCCAATCGGCTTAATGCAGAGAATGAAAAAGACTCCAGGAGGCGGCAAGCCCGGCTGCAGAAAGAGCTTGCAGAAGCAGCAAAGG AACCTCTACCAGTCGAACAGGATGATGACATTGAGGTCATTGTGGATGAAACTTCTGATCACACAGAAGAGACCTCTCCTGTGCGAGCCA TCAGCAGAGCAGCCACGAGACGCTCTGTCTCTTCCTTCCCAGTCCCCCAGGACAATGTGGATACTCATCCTGGTTCTGGTAAAGAAGTGA GGGTACCAGCTACTGCCTTGTGTGTCTTCGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCCGGTTACTGGCCA CTGGAGGCATGGACCGCAGGGTTAAGCTTTGGGAAGTATTTGGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCAGTAATGCAGGAA TTACAAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGATGATTATC GATTACGGCTATTCCTTGAGCGAGAGCGGGCAGCCCAGCTAGCAGAAAGTAAAACAGATGAGTTGATCAAAGATGCTCCCACCACTCAGC ATGATAAGAGTGGAGAGTGGCAAGAAACAAGTGGAGAAATACAGTGGGTGTCAACTGAAAAGACTGATGGTACAGAAGAGAAACATAAGA AGGAGGAGGAGGATGAAGAACTTGACCTCAATAAAGCCCTTCAGCATGCCGGCAAACACATGGAGGATTGCATTGTGGCCTCCTACACAG CACTACTTCTTGGGTGTCTCTGCCAGGAAAGTCCAATCAATGTAACCACTGTGCGGGAATATCTGCCAGAAGGAGACTTTTCAATAATGA CAGAGATGCTCAAAAAATTTTTGAGTTTTATGAATCTCACTTGTGCTGTTGGAACAACTGGCCAGAAATCTATCTCTAGAGTGATTGAAT ATTTGGAACATTGCTAGCTGCTTTACCTTTGCTTCAGGTGCTCGGTAATGCTGGAGCTATCCTTAGACAAAGAAAAGTCAAGTCATGAAA GAAGTCCTTGAAGATATACCAAGAACATTCATCAGTATCATTCGTGTTTGGATTTTTAAGGCCACCTGATTTCTTCGTCATGCATTCGGC ATTTGCTAAATGACAGTTACTACATCAATCTGCAACTATCAAAAATGAGGGGAAAAGGTTCAGGCTGTTAACAATTCCATGCAGTATTTA AATACATTTACTTTGGCAGAGTTTATACCCTCCCCTTGTTTTCTTGCTTTATTCTGGGCAAGTTTGAAGGGGAAAATTTGTGCTGCTGTT AGTGCAACTGCTGTGTATGTTGAGCCACTGTTGTCATGCCAGCCAGGTGCAAAGGCAGCTTAGCTACTGAGGTAGCGAATGTTCTGAGGA CATTCTAGACAACAGCTTAGTTCCTTTTTCAGGCTCATTTGCTTTTGCTTTTTTGTTGAATGATTCCAATCGTAAATAAAGCTTTTAATA >7537_7537_13_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000392020_WAPAL_chr10_88206206_ENST00000263070_length(amino acids)=534AA_BP=382 MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEISPGHDGTWNDNQLQEMAQLRI KHQEELTELHKKRGELAQLVIDLNNQMQRKDREMQMNEAKIAECLQTISDLETECLDLRTKLCDLERANQTLKDEYDALQITFTALEGKL RKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAISRAATRRSVS SFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGS YLLAASNDFASRIWTVDDYRLRLFLERERAAQLAESKTDELIKDAPTTQHDKSGEWQETSGEIQWVSTEKTDGTEEKHKKEEEDEELDLN -------------------------------------------------------------- >7537_7537_14_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000392020_WAPAL_chr10_88206206_ENST00000298767_length(transcript)=4014nt_BP=1268nt GTGTGGAGGTGAGCTCCGGGATTGCCGGCATTCCCGCTTCTGCTGGTTGCTTCATGCTGCAGGCTGCGGCCGTCAGCCCTCGCTCGCATT GGTGGCGCTGAGGTGCCGGGGCAGCAAGTGACATGTCGTCGGGCCTCCGCGCCGCTGACTTCCCCCGCTGGAAGCGCCACATCTCGGAGC AACTGAGGCGCCGGGACCGGCTGCAGAGACAGGCGTTCGAGGAGATCATCCTGCAGTATAACAAATTGCTGGAAAAGTCAGATCTTCATT CAGTGTTGGCCCAGAAACTACAGGCTGAAAAGCATGACGTACCAAACAGGCACGAGATAAGTCCCGGACATGATGGCACATGGAATGACA ATCAGCTACAAGAAATGGCCCAACTGAGGATTAAGCACCAAGAGGAACTGACTGAATTACACAAGAAACGTGGGGAGTTAGCTCAACTGG TGATTGACCTGAATAACCAAATGCAGCGGAAGGACAGGGAGATGCAGATGAATGAAGCAAAAATTGCAGAATGTTTGCAGACTATCTCTG ACCTGGAGACGGAGTGCCTAGACCTGCGCACTAAGCTTTGTGACCTTGAAAGAGCCAACCAGACCCTGAAGGATGAATATGATGCCCTGC AGATCACTTTTACTGCCTTGGAGGGAAAACTGAGGAAAACTACGGAAGAGAACCAGGAGCTGGTCACCAGATGGATGGCTGAGAAAGCCC AGGAAGCCAATCGGCTTAATGCAGAGAATGAAAAAGACTCCAGGAGGCGGCAAGCCCGGCTGCAGAAAGAGCTTGCAGAAGCAGCAAAGG AACCTCTACCAGTCGAACAGGATGATGACATTGAGGTCATTGTGGATGAAACTTCTGATCACACAGAAGAGACCTCTCCTGTGCGAGCCA TCAGCAGAGCAGCCACGAGACGCTCTGTCTCTTCCTTCCCAGTCCCCCAGGACAATGTGGATACTCATCCTGGTTCTGGTAAAGAAGTGA GGGTACCAGCTACTGCCTTGTGTGTCTTCGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCCGGTTACTGGCCA CTGGAGGCATGGACCGCAGGGTTAAGCTTTGGGAAGTATTTGGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCAGTAATGCAGGAA TTACAAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGATGATTATC GATTACGGCTATTCCTTGAGCGAGAGCGGGCAGCCCAGCTAGCAGAAAGTAAAACAGATGAGTTGATCAAAGATGCTCCCACCACTCAGC ATGATAAGAGTGGAGAGTGGCAAGAAACAAGTGGAGAAATACAGTGGGTGTCAACTGAAAAGACTGATGGTACAGAAGAGAAACATAAGA AGGAGGAGGAGGATGAAGAACTTGACCTCAATAAAGCCCTTCAGCATGCCGGCAAACACATGGAGGATTGCATTGTGGCCTCCTACACAG CACTACTTCTTGGGTGTCTCTGCCAGGAAAGTCCAATCAATGTAACCACTGTGCGGGAATATCTGCCAGAAGGAGACTTTTCAATAATGA CAGAGATGCTCAAAAAATTTTTGAGTTTTATGAATCTCACTTGTGCTGTTGGAACAACTGGCCAGAAATCTATCTCTAGAGTGATTGAAT ATTTGGAACATTGCTAGCTGCTTTACCTTTGCTTCAGGTGCTCGGTAATGCTGGAGCTATCCTTAGACAAAGAAAAGTCAAGTCATGAAA GAAGTCCTTGAAGATATACCAAGAACATTCATCAGTATCATTCGTGTTTGGATTTTTAAGGCCACCTGATTTCTTCGTCATGCATTCGGC ATTTGCTAAATGACAGTTACTACATCAATCTGCAACTATCAAAAATGAGGGGAAAAGGTTCAGGCTGTTAACAATTCCATGCAGTATTTA AATACATTTACTTTGGCAGAGTTTATACCCTCCCCTTGTTTTCTTGCTTTATTCTGGGCAAGTTTGAAGGGGAAAATTTGTGCTGCTGTT AGTGCAACTGCTGTGTATGTTGAGCCACTGTTGTCATGCCAGCCAGGTGCAAAGGCAGCTTAGCTACTGAGGTAGCGAATGTTCTGAGGA CATTCTAGACAACAGCTTAGTTCCTTTTTCAGGCTCATTTGCTTTTGCTTTTTTGTTGAATGATTCCAATCGTAAATAAAGCTTTTAATA ATTTTGTGAATTTTTTGGTTGTTGTTCCCTGAACTACTGTCTATATTTAAAATTAGATGGAATCCAAAGATACACGGGATTAATAGTATA TTTTTTTATTCTTGATTAGGTTTGGGTTATTGAACTATTTTTTACTTTTGAGACCACAACCATATTCAATATCATACCATAATGTGTCAT AGCTATAGGCACAAGAAAAACAACAGTTTGAGAGAATATTATATAAGATGATGTGCCCTGTTAAAAGGAGGAGGCAAAATAGTCAAACCC AGGGTAGTTTACACTTAATGCTAGGGAGGCTCTTAAAACATTATTAGATTTTGAGGAAAGACTCTCTAGATATATTTTCTAATGTTCAGT ACAATAAATATAAGGAAGCTAAAACACCAATGTGGAATTCCTGTTTCCAGATAACATGTATATTCTTCTATAGAGTGACAGGATCAATTG CATAAGCGCAAAGCCTTAAATTGCTGGTTTAGAGAAGACCCTTTTTTCATTCAGATTCTTTGTTCGTAGAGCAGTTATTTGAAAAACAGT TATGGAACACAAAACATTTTATAGATTTAATATCATAACATTGCAAATTTTTCTTGTATTATTCACACCACTGGTTATACTTTTTTTTTT CCTTTTTTATTGATTGGGCCTGAATACAGGCTTTCTAGAGATCTTTTTCATTAATACTTTTAAATACCTTTCAGGTAGTTACATCATGTT TCTTCATTGGATTTGTAAAACTTGAAGCCATAAAAATATTAGTTTGGTGTGTATTGGGGAAAATAGCTAAAAGTCTAATTTTTACCCATT TAGACTTTGTTATTTCCTTGTATAAAGTGACAAATCGGGGCTCTTGTATCAGTGCCAGCTGTAATGTTTTTAAATGCAGTGGCTGCCTTC TATTGTCTTCCTATTTTTGATAATGCAGATTGTTGGGAAATCTGTAAGGAAGTAACTGATTCCAGGCAAATTGTTTTCTTCCTTCTACCC ACCCCAACCCCTACCCATCACCTTTTAAGAACATAGTACGCCAGTGTAACGTGGGAACCATTGAGATTGTATTTGCCCTGAGTATTAAAG CTAGCTTAGCAAAATACTTTTAAAAACATATTGGTAAATGATACCCGTAAAATTAAATTAGTTATATTTTATTTTAAAATGCAAAATACA TTGATATTTATTAATCATTGGATTTAGGGAAAGGGACAGATTTTTGGTGAACCTGACTTGTGGCAGATGGTAAGGAATATTATAAAACAT TTGGATGAGAACAATCAGGGCGAACTGCATTTTTCTGTTACACTGGTAATCATTTGAAAATTGATTTACCTCAGTGTTTAACAGTTTTTT GTTTTGTTTTGTTTTTTAAATAATAACTAATTGTCGAGCACTGATAGAGATGCAGATTTTGGTGGGGGGAGGTGGTGGGGGAGATAATCA CTTCACCAACTGCAGTGCATTTGTGTGTTTTTAACCCTCAGAGAACTCTGCATTTTAGGGTACTTGAGGCTGACTTAACTAAAAGTTTTA AAGTAACCTTTTTTCCATTGTAAATATTTCTGTAAATACTACCAATTGGAAATTAGAACAGTAGAGTACTTTTCTGAATCCAATCCTATT TTTATTTTATACAGTATTTCTCAGCTGTGATCTTTGGAGCAAAAGCCAACGGCAGGAAAAAATAGTTTGTACCAGTTTCATGAAGTATGT >7537_7537_14_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000392020_WAPAL_chr10_88206206_ENST00000298767_length(amino acids)=534AA_BP=382 MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEISPGHDGTWNDNQLQEMAQLRI KHQEELTELHKKRGELAQLVIDLNNQMQRKDREMQMNEAKIAECLQTISDLETECLDLRTKLCDLERANQTLKDEYDALQITFTALEGKL RKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAISRAATRRSVS SFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGS YLLAASNDFASRIWTVDDYRLRLFLERERAAQLAESKTDELIKDAPTTQHDKSGEWQETSGEIQWVSTEKTDGTEEKHKKEEEDEELDLN -------------------------------------------------------------- >7537_7537_15_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000392020_WAPAL_chr10_88206206_ENST00000372075_length(transcript)=2260nt_BP=1268nt GTGTGGAGGTGAGCTCCGGGATTGCCGGCATTCCCGCTTCTGCTGGTTGCTTCATGCTGCAGGCTGCGGCCGTCAGCCCTCGCTCGCATT GGTGGCGCTGAGGTGCCGGGGCAGCAAGTGACATGTCGTCGGGCCTCCGCGCCGCTGACTTCCCCCGCTGGAAGCGCCACATCTCGGAGC AACTGAGGCGCCGGGACCGGCTGCAGAGACAGGCGTTCGAGGAGATCATCCTGCAGTATAACAAATTGCTGGAAAAGTCAGATCTTCATT CAGTGTTGGCCCAGAAACTACAGGCTGAAAAGCATGACGTACCAAACAGGCACGAGATAAGTCCCGGACATGATGGCACATGGAATGACA ATCAGCTACAAGAAATGGCCCAACTGAGGATTAAGCACCAAGAGGAACTGACTGAATTACACAAGAAACGTGGGGAGTTAGCTCAACTGG TGATTGACCTGAATAACCAAATGCAGCGGAAGGACAGGGAGATGCAGATGAATGAAGCAAAAATTGCAGAATGTTTGCAGACTATCTCTG ACCTGGAGACGGAGTGCCTAGACCTGCGCACTAAGCTTTGTGACCTTGAAAGAGCCAACCAGACCCTGAAGGATGAATATGATGCCCTGC AGATCACTTTTACTGCCTTGGAGGGAAAACTGAGGAAAACTACGGAAGAGAACCAGGAGCTGGTCACCAGATGGATGGCTGAGAAAGCCC AGGAAGCCAATCGGCTTAATGCAGAGAATGAAAAAGACTCCAGGAGGCGGCAAGCCCGGCTGCAGAAAGAGCTTGCAGAAGCAGCAAAGG AACCTCTACCAGTCGAACAGGATGATGACATTGAGGTCATTGTGGATGAAACTTCTGATCACACAGAAGAGACCTCTCCTGTGCGAGCCA TCAGCAGAGCAGCCACGAGACGCTCTGTCTCTTCCTTCCCAGTCCCCCAGGACAATGTGGATACTCATCCTGGTTCTGGTAAAGAAGTGA GGGTACCAGCTACTGCCTTGTGTGTCTTCGATGCACATGATGGGGAAGTCAACGCTGTGCAGTTCAGTCCAGGTTCCCGGTTACTGGCCA CTGGAGGCATGGACCGCAGGGTTAAGCTTTGGGAAGTATTTGGAGAAAAATGTGAGTTCAAGGGTTCCCTATCTGGCAGTAATGCAGGAA TTACAAGCATTGAATTTGATAGTGCTGGATCTTACCTCTTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGATGATTATC GATTACGGCTATTCCTTGAGCGAGAGCGGGCAGCCCAGCTAGCAGAAAGTAAAACAGATGAGTTGATCAAAGATGCTCCCACCACTCAGC ATGATAAGAGTGGAGAGTGGCAAGAAACAAGTGGAGAAATACAGTGGGTGTCAACTGAAAAGACTGATGGTACAGAAGAGAAACATAAGA AGGAGGAGGAGGATGAAGAACTTGACCTCAATAAAGCCCTTCAGCATGCCGGCAAACACATGGAGGATTGCATTGTGGCCTCCTACACAG CACTACTTCTTGGGTGTCTCTGCCAGGAAAGTCCAATCAATGTAACCACTGTGCGGGAATATCTGCCAGAAGGAGACTTTTCAATAATGA CAGAGATGCTCAAAAAATTTTTGAGTTTTATGAATCTCACTTGTGCTGTTGGAACAACTGGCCAGAAATCTATCTCTAGAGTGATTGAAT ATTTGGAACATTGCTAGCTGCTTTACCTTTGCTTCAGGTGCTCGGTAATGCTGGAGCTATCCTTAGACAAAGAAAAGTCAAGTCATGAAA GAAGTCCTTGAAGATATACCAAGAACATTCATCAGTATCATTCGTGTTTGGATTTTTAAGGCCACCTGATTTCTTCGTCATGCATTCGGC ATTTGCTAAATGACAGTTACTACATCAATCTGCAACTATCAAAAATGAGGGGAAAAGGTTCAGGCTGTTAACAATTCCATGCAGTATTTA AATACATTTACTTTGGCAGAGTTTATACCCTCCCCTTGTTTTCTTGCTTTATTCTGGGCAAGTTTGAAGGGGAAAATTTGTGCTGCTGTT AGTGCAACTGCTGTGTATGTTGAGCCACTGTTGTCATGCCAGCCAGGTGCAAAGGCAGCTTAGCTACTGAGGTAGCGAATGTTCTGAGGA CATTCTAGACAACAGCTTAGTTCCTTTTTCAGGCTCATTTGCTTTTGCTTTTTTGTTGAATGATTCCAATCGTAAATAAAGCTTTTAATA >7537_7537_15_ATG16L1-WAPAL_ATG16L1_chr2_234191399_ENST00000392020_WAPAL_chr10_88206206_ENST00000372075_length(amino acids)=534AA_BP=382 MSSGLRAADFPRWKRHISEQLRRRDRLQRQAFEEIILQYNKLLEKSDLHSVLAQKLQAEKHDVPNRHEISPGHDGTWNDNQLQEMAQLRI KHQEELTELHKKRGELAQLVIDLNNQMQRKDREMQMNEAKIAECLQTISDLETECLDLRTKLCDLERANQTLKDEYDALQITFTALEGKL RKTTEENQELVTRWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSPVRAISRAATRRSVS SFPVPQDNVDTHPGSGKEVRVPATALCVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEVFGEKCEFKGSLSGSNAGITSIEFDSAGS YLLAASNDFASRIWTVDDYRLRLFLERERAAQLAESKTDELIKDAPTTQHDKSGEWQETSGEIQWVSTEKTDGTEEKHKKEEEDEELDLN -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for ATG16L1-WAPAL |
Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
Hgene | Hgene's interactors | Tgene | Tgene's interactors |
- Retained PPIs in in-frame fusion. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000347464 | + | 8 | 14 | 13_43 | 238.0 | 445.0 | ATG5 |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000373525 | + | 9 | 15 | 13_43 | 222.0 | 429.0 | ATG5 |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000392017 | + | 12 | 18 | 13_43 | 401.0 | 608.0 | ATG5 |
Hgene | ATG16L1 | chr2:234191399 | chr10:88206206 | ENST00000392020 | + | 11 | 17 | 13_43 | 382.0 | 589.0 | ATG5 |
- Lost PPIs in in-frame fusion. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
- Retained PPIs, but lost function due to frame-shift fusion. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for ATG16L1-WAPAL |
Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for ATG16L1-WAPAL |
Diseases associated with fusion partners. (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Hgene | ATG16L1 | C1970207 | Inflammatory Bowel Disease 10 | 11 | CTD_human;UNIPROT |
Hgene | ATG16L1 | C0010346 | Crohn Disease | 2 | CTD_human;GENOMICS_ENGLAND |
Hgene | ATG16L1 | C0156147 | Crohn's disease of large bowel | 2 | CTD_human |
Hgene | ATG16L1 | C0267380 | Crohn's disease of the ileum | 2 | CTD_human |
Hgene | ATG16L1 | C0678202 | Regional enteritis | 2 | CTD_human |
Hgene | ATG16L1 | C0949272 | IIeocolitis | 2 | CTD_human |
Hgene | ATG16L1 | C0021390 | Inflammatory Bowel Diseases | 1 | CTD_human |