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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ANO1-CDC42BPG (FusionGDB2 ID:HG55107TG55561)

Fusion Gene Summary for ANO1-CDC42BPG

check button Fusion gene summary
Fusion gene informationFusion gene name: ANO1-CDC42BPG
Fusion gene ID: hg55107tg55561
HgeneTgene
Gene symbol

ANO1

CDC42BPG

Gene ID

55107

55561

Gene nameanoctamin 1CDC42 binding protein kinase gamma
SynonymsDOG1|ORAOV2|TAOS2|TMEM16ADMPK2|HSMDPKIN|KAPPA-200|MRCKG|MRCKgamma
Cytomap('ANO1')('CDC42BPG')

11q13.3

11q13.1

Type of geneprotein-codingprotein-coding
Descriptionanoctamin-1Ca2+-activated Cl- channelanoctamin 1, calcium activated chloride channelcalcium activated chloride channeldiscovered on gastrointestinal stromal tumors protein 1oral cancer overexpressed 2transmembrane protein 16A (eight membrane-spanninserine/threonine-protein kinase MRCK gammaCDC42 binding protein kinase gamma (DMPK-like)DMPK-like gammaMRCK gammamyotonic dystrophy kinase-related CDC42-binding kinase gammamyotonic dystrophy protein kinase like proteinmyotonic dystrophy protein kin
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000316296, ENST00000355303, 
ENST00000398543, ENST00000530676, 
ENST00000538023, ENST00000525494, 
ENST00000531349, 
Fusion gene scores* DoF score20 X 18 X 9=32405 X 5 X 5=125
# samples 205
** MAII scorelog2(20/3240*10)=-4.01792190799726
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/125*10)=-1.32192809488736
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ANO1 [Title/Abstract] AND CDC42BPG [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointANO1(69951894)-CDC42BPG(64606374), # samples:1
Anticipated loss of major functional domain due to fusion event.ANO1-CDC42BPG seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ANO1-CDC42BPG seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ANO1-CDC42BPG seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ANO1-CDC42BPG seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneANO1

GO:0006812

cation transport

22946059

TgeneCDC42BPG

GO:0006468

protein phosphorylation

15194684


check buttonFusion gene breakpoints across ANO1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across CDC42BPG (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4TGCTTCGA-2G-AAGP-01AANO1chr11

69951894

-CDC42BPGchr11

64606374

-


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Fusion Gene ORF analysis for ANO1-CDC42BPG

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000316296ENST00000491280ANO1chr11

69951894

-CDC42BPGchr11

64606374

-
5CDS-intronENST00000355303ENST00000491280ANO1chr11

69951894

-CDC42BPGchr11

64606374

-
5CDS-intronENST00000398543ENST00000491280ANO1chr11

69951894

-CDC42BPGchr11

64606374

-
5CDS-intronENST00000530676ENST00000491280ANO1chr11

69951894

-CDC42BPGchr11

64606374

-
5CDS-intronENST00000538023ENST00000491280ANO1chr11

69951894

-CDC42BPGchr11

64606374

-
In-frameENST00000316296ENST00000342711ANO1chr11

69951894

-CDC42BPGchr11

64606374

-
In-frameENST00000355303ENST00000342711ANO1chr11

69951894

-CDC42BPGchr11

64606374

-
In-frameENST00000398543ENST00000342711ANO1chr11

69951894

-CDC42BPGchr11

64606374

-
In-frameENST00000530676ENST00000342711ANO1chr11

69951894

-CDC42BPGchr11

64606374

-
In-frameENST00000538023ENST00000342711ANO1chr11

69951894

-CDC42BPGchr11

64606374

-
intron-3CDSENST00000525494ENST00000342711ANO1chr11

69951894

-CDC42BPGchr11

64606374

-
intron-3CDSENST00000531349ENST00000342711ANO1chr11

69951894

-CDC42BPGchr11

64606374

-
intron-intronENST00000525494ENST00000491280ANO1chr11

69951894

-CDC42BPGchr11

64606374

-
intron-intronENST00000531349ENST00000491280ANO1chr11

69951894

-CDC42BPGchr11

64606374

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000355303ANO1chr1169951894-ENST00000342711CDC42BPGchr1164606374-5918105222148311536
ENST00000398543ANO1chr1169951894-ENST00000342711CDC42BPGchr1164606374-56627964945751508
ENST00000538023ANO1chr1169951894-ENST00000342711CDC42BPGchr1164606374-56627964945751508
ENST00000316296ANO1chr1169951894-ENST00000342711CDC42BPGchr1164606374-563476810545471480
ENST00000530676ANO1chr1169951894-ENST00000342711CDC42BPGchr1164606374-575488824946671472

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000355303ENST00000342711ANO1chr1169951894-CDC42BPGchr1164606374-0.0049332320.99506676
ENST00000398543ENST00000342711ANO1chr1169951894-CDC42BPGchr1164606374-0.0037838110.99621624
ENST00000538023ENST00000342711ANO1chr1169951894-CDC42BPGchr1164606374-0.0037838110.99621624
ENST00000316296ENST00000342711ANO1chr1169951894-CDC42BPGchr1164606374-0.0040742060.9959258
ENST00000530676ENST00000342711ANO1chr1169951894-CDC42BPGchr1164606374-0.005776660.9942233

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Fusion Genomic Features for ANO1-CDC42BPG


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for ANO1-CDC42BPG


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:69951894/chr11:64606374)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneCDC42BPGchr11:69951894chr11:64606374ENST00000342711637406_6782921552.0Coiled coilOntology_term=ECO:0000255
TgeneCDC42BPGchr11:69951894chr11:64606374ENST00000342711637730_8022921552.0Coiled coilOntology_term=ECO:0000255
TgeneCDC42BPGchr11:69951894chr11:64606374ENST000003427116371092_13662921552.0DomainCNH
TgeneCDC42BPGchr11:69951894chr11:64606374ENST000003427116371437_14502921552.0DomainCRIB
TgeneCDC42BPGchr11:69951894chr11:64606374ENST00000342711637338_4082921552.0DomainAGC-kinase C-terminal
TgeneCDC42BPGchr11:69951894chr11:64606374ENST00000342711637947_10662921552.0DomainPH
TgeneCDC42BPGchr11:69951894chr11:64606374ENST00000342711637878_9272921552.0Zinc fingerPhorbol-ester/DAG-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneANO1chr11:69951894chr11:64606374ENST00000316296-5171_333221643.0Topological domainCytoplasmic
HgeneANO1chr11:69951894chr11:64606374ENST00000316296-517355_406221643.0Topological domainExtracellular
HgeneANO1chr11:69951894chr11:64606374ENST00000316296-517428_519221643.0Topological domainCytoplasmic
HgeneANO1chr11:69951894chr11:64606374ENST00000316296-517541_568221643.0Topological domainExtracellular
HgeneANO1chr11:69951894chr11:64606374ENST00000316296-517590_607221643.0Topological domainCytoplasmic
HgeneANO1chr11:69951894chr11:64606374ENST00000316296-517629_657221643.0Topological domainExtracellular
HgeneANO1chr11:69951894chr11:64606374ENST00000316296-517679_725221643.0Topological domainCytoplasmic
HgeneANO1chr11:69951894chr11:64606374ENST00000316296-517768_784221643.0Topological domainCytoplasmic
HgeneANO1chr11:69951894chr11:64606374ENST00000316296-517806_892221643.0Topological domainExtracellular
HgeneANO1chr11:69951894chr11:64606374ENST00000316296-517914_986221643.0Topological domainCytoplasmic
HgeneANO1chr11:69951894chr11:64606374ENST00000355303-5261_333249987.0Topological domainCytoplasmic
HgeneANO1chr11:69951894chr11:64606374ENST00000355303-526355_406249987.0Topological domainExtracellular
HgeneANO1chr11:69951894chr11:64606374ENST00000355303-526428_519249987.0Topological domainCytoplasmic
HgeneANO1chr11:69951894chr11:64606374ENST00000355303-526541_568249987.0Topological domainExtracellular
HgeneANO1chr11:69951894chr11:64606374ENST00000355303-526590_607249987.0Topological domainCytoplasmic
HgeneANO1chr11:69951894chr11:64606374ENST00000355303-526629_657249987.0Topological domainExtracellular
HgeneANO1chr11:69951894chr11:64606374ENST00000355303-526679_725249987.0Topological domainCytoplasmic
HgeneANO1chr11:69951894chr11:64606374ENST00000355303-526768_784249987.0Topological domainCytoplasmic
HgeneANO1chr11:69951894chr11:64606374ENST00000355303-526806_892249987.0Topological domainExtracellular
HgeneANO1chr11:69951894chr11:64606374ENST00000355303-526914_986249987.0Topological domainCytoplasmic
HgeneANO1chr11:69951894chr11:64606374ENST00000398543-5241_333133841.0Topological domainCytoplasmic
HgeneANO1chr11:69951894chr11:64606374ENST00000398543-524355_406133841.0Topological domainExtracellular
HgeneANO1chr11:69951894chr11:64606374ENST00000398543-524428_519133841.0Topological domainCytoplasmic
HgeneANO1chr11:69951894chr11:64606374ENST00000398543-524541_568133841.0Topological domainExtracellular
HgeneANO1chr11:69951894chr11:64606374ENST00000398543-524590_607133841.0Topological domainCytoplasmic
HgeneANO1chr11:69951894chr11:64606374ENST00000398543-524629_657133841.0Topological domainExtracellular
HgeneANO1chr11:69951894chr11:64606374ENST00000398543-524679_725133841.0Topological domainCytoplasmic
HgeneANO1chr11:69951894chr11:64606374ENST00000398543-524768_784133841.0Topological domainCytoplasmic
HgeneANO1chr11:69951894chr11:64606374ENST00000398543-524806_892133841.0Topological domainExtracellular
HgeneANO1chr11:69951894chr11:64606374ENST00000398543-524914_986133841.0Topological domainCytoplasmic
HgeneANO1chr11:69951894chr11:64606374ENST00000530676-5251_333133819.3333333333334Topological domainCytoplasmic
HgeneANO1chr11:69951894chr11:64606374ENST00000530676-525355_406133819.3333333333334Topological domainExtracellular
HgeneANO1chr11:69951894chr11:64606374ENST00000530676-525428_519133819.3333333333334Topological domainCytoplasmic
HgeneANO1chr11:69951894chr11:64606374ENST00000530676-525541_568133819.3333333333334Topological domainExtracellular
HgeneANO1chr11:69951894chr11:64606374ENST00000530676-525590_607133819.3333333333334Topological domainCytoplasmic
HgeneANO1chr11:69951894chr11:64606374ENST00000530676-525629_657133819.3333333333334Topological domainExtracellular
HgeneANO1chr11:69951894chr11:64606374ENST00000530676-525679_725133819.3333333333334Topological domainCytoplasmic
HgeneANO1chr11:69951894chr11:64606374ENST00000530676-525768_784133819.3333333333334Topological domainCytoplasmic
HgeneANO1chr11:69951894chr11:64606374ENST00000530676-525806_892133819.3333333333334Topological domainExtracellular
HgeneANO1chr11:69951894chr11:64606374ENST00000530676-525914_986133819.3333333333334Topological domainCytoplasmic
HgeneANO1chr11:69951894chr11:64606374ENST00000316296-517334_354221643.0TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000316296-517407_427221643.0TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000316296-517520_540221643.0TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000316296-517569_589221643.0TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000316296-517608_628221643.0TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000316296-517658_678221643.0TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000316296-517726_746221643.0TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000316296-517747_767221643.0TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000316296-517785_805221643.0TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000316296-517893_913221643.0TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000355303-526334_354249987.0TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000355303-526407_427249987.0TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000355303-526520_540249987.0TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000355303-526569_589249987.0TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000355303-526608_628249987.0TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000355303-526658_678249987.0TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000355303-526726_746249987.0TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000355303-526747_767249987.0TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000355303-526785_805249987.0TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000355303-526893_913249987.0TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000398543-524334_354133841.0TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000398543-524407_427133841.0TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000398543-524520_540133841.0TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000398543-524569_589133841.0TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000398543-524608_628133841.0TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000398543-524658_678133841.0TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000398543-524726_746133841.0TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000398543-524747_767133841.0TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000398543-524785_805133841.0TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000398543-524893_913133841.0TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000530676-525334_354133819.3333333333334TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000530676-525407_427133819.3333333333334TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000530676-525520_540133819.3333333333334TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000530676-525569_589133819.3333333333334TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000530676-525608_628133819.3333333333334TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000530676-525658_678133819.3333333333334TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000530676-525726_746133819.3333333333334TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000530676-525747_767133819.3333333333334TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000530676-525785_805133819.3333333333334TransmembraneHelical
HgeneANO1chr11:69951894chr11:64606374ENST00000530676-525893_913133819.3333333333334TransmembraneHelical
TgeneCDC42BPGchr11:69951894chr11:64606374ENST0000034271163771_3372921552.0DomainProtein kinase
TgeneCDC42BPGchr11:69951894chr11:64606374ENST0000034271163777_852921552.0Nucleotide bindingATP


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Fusion Gene Sequence for ANO1-CDC42BPG


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>4847_4847_1_ANO1-CDC42BPG_ANO1_chr11_69951894_ENST00000316296_CDC42BPG_chr11_64606374_ENST00000342711_length(transcript)=5634nt_BP=768nt
ACGCACACTGAGTCCAGGTCCTCCTGAAGGTCACCAGCACAGCGGGGCCCTGTGTTACTGTAGAGAGAAGTCAGTTGCTTAGTTTCAGCC
TCCTGCCGGCACCAGATGCTGACCAGGCCCTCCCAGGTGCTGCTGAACTCCTTATCTGTGGACCCTGATGCCGAGTGCAAGTATGGCCTG
TACTTCAGGGACGGCCGGCGCAAGGTGGACTACATCCTGGTGTACCATCACAAGAGGCCCTCGGGCAACCGGACCCTGGTCAGGAGGGTG
CAGCACAGCGACACCCCCTCTGGGGCTCGCAGCGTCAAGCAGGACCACCCCCTGCCGGGCAAGGGGGCGTCGCTGGATGCAGGCTCGGGG
GAGCCCCCGATGGACTACCACGAGGATGACAAGCGCTTCCGCAGGGAGGAGTACGAGGGCAACCTCCTGGAGGCGGGCCTGGAGCTGGAG
CGGGACGAGGACACTAAAATCCACGGAGTCGGGTTTGTGAAAATCCATGCCCCCTGGAACGTGCTGTGCAGAGAGGCCGAGTTTCTGAAA
CTGAAGATGCCGACGAAGAAGATGTACCACATTAATGAGACCCGTGGCCTCCTGAAAAAAATCAACTCTGTGCTCCAGAAAATCACAGAT
CCCATCCAGCCCAAAGTGGCTGAGCACAGGCCCCAGACCATGAAGAGACTCTCCTATCCCTTCTCCCGGGAGAAGCAGCATCTATTTGAC
TTGTCTGATAAGGATTCCTTTTTCGACAGCAAAACCCGGAGCACGATTGACCACCTGCAGTTCCCCCCGGACGTGCCTGACGTGCCAGCC
AGCGCCCAAGACCTGATCCGCCAGCTGCTGTGTCGCCAGGAAGAGCGGCTAGGCCGTGGTGGGCTGGATGACTTCCGGAACCATCCTTTC
TTCGAAGGCGTGGACTGGGAGCGGCTGGCGAGCAGCACGGCCCCCTATATTCCTGAGCTGCGGGGGCCCATGGACACCTCCAACTTTGAT
GTGGATGACGACACCCTCAACCATCCAGGGACCCTGCCACCGCCCTCCCACGGGGCCTTCTCCGGCCATCACCTGCCATTCGTGGGCTTC
ACCTACACCTCAGGCAGTCACAGTCCTGAGAGCAGCTCTGAGGCTTGGGCTGCCCTGGAGCGGAAGCTCCAGTGTCTGGAGCAGGAGAAG
GTGGAGCTGAGCAGGAAGCACCAAGAGGCCCTGCACGCCCCCACAGACCATCGGGAGCTGGAGCAGCTACGGAAGGAAGTGCAGACTCTG
CGGGACAGGCTGCCAGAGATGCTGAGGGACAAGGCCTCATTGTCCCAGACGGATGGGCCCCCAGCTGGTAGCCCAGGTCAGGACAGTGAC
CTACGGCAGGAGCTTGACCGACTTCACCGGGAGCTGGCCGAGGGTCGGGCAGGGCTGCAGGCTCAGGAGCAGGAGCTCTGCAGGGCCCAG
GGGCAGCAGGAGGAGCTGCTTCAGAGGCTACAGGAGGCCCAGGAGAGAGAGGCGGCCACAGCTAGCCAGACCCGGGCCCTGAGCTCCCAG
CTGGAGGAAGCCCGGGCTGCCCAGAGGGAGCTGGAGGCCCAGGTGTCCTCCCTGAGCCGGCAGGTGACGCAGCTGCAGGGACAGTGGGAG
CAACGCCTTGAGGAGTCGTCCCAGGCCAAGACCATCCACACAGCCTCTGAGACCAACGGGATGGGACCCCCTGAGGGTGGGCCTCAGGAG
GCCCAACTGAGGAAGGAGGTGGCCGCCCTGCGAGAGCAGCTGGAGCAGGCCCACAGCCACAGGCCGAGTGGTAAGGAGGAGGCTCTGTGC
CAGCTGCAGGAGGAAAACCGGAGGCTGAGCCGGGAGCAGGAGCGGCTAGAAGCAGAGCTGGCCCAGGAGCAGGAGAGCAAGCAGCGGCTG
GAGGGTGAGCGGCGGGAGACGGAGAGCAACTGGGAGGCCCAGCTCGCCGACATCCTCAGCTGGGTGAATGATGAGAAGGTCTCAAGAGGC
TACCTGCAGGCCCTGGCCACCAAGATGGCAGAGGAGCTGGAGTCCTTGAGGAACGTAGGCACCCAGACGCTCCCTGCCCGGCCACTGGAC
CACCAGTGGAAGGCGCGGCGACTGCAGAAGATGGAGGCCTCGGCCAGGCTGGAGCTGCAGTCAGCGCTGGAGGCCGAGATCCGCGCCAAG
CAGGGCCTGCAGGAGCGGCTGACACAGGTGCAGGAGGCCCAGCTGCAGGCTGAGCGCCGTCTGCAGGAGGCCGAGAAGCAGAGCCAGGCC
CTGCAACAGGAGCTCGCCATGCTGCGGGAGGAGCTGCGGGCCCGAGGGCCAGTGGACACCAAGCCCTCAAACTCCCTGATTCCCTTCCTG
TCCTTCCGGAGCTCAGAGAAGGATTCTGCCAAGGACCCTGGCATCTCAGGAGAGGCCACAAGGCATGGAGGAGAGCCAGATCTGAGGCCG
GAGGGCCGACGCAGCCTGCGCATGGGGGCTGTGTTCCCCAGAGCACCCACTGCCAACACAGCCTCTACAGAAGGTCTTCCTGCTAAGCCC
GGCTCACACACGCTGCGCCCCCGGAGCTTCCCATCCCCGACCAAGTGTCTCCGCTGCACCTCGCTGATGCTGGGCCTGGGCCGCCAGGGC
CTGGGTTGTGATGCCTGCGGCTACTTTTGTCACACAACCTGTGCCCCACAGGCCCCACCCTGCCCCGTGCCCCCTGACCTCCTCCGCACA
GCCCTGGGAGTACACCCCGAAACAGGCACAGGCACTGCCTATGAGGGCTTTCTGTCGGTGCCGCGGCCCTCAGGTGTCCGGCGGGGCTGG
CAGCGCGTGTTTGCTGCCCTGAGTGACTCACGCCTGCTGCTGTTTGACGCCCCTGACCTGAGGCTCAGCCCGCCCAGTGGGGCCCTCCTG
CAGGTCCTAGATCTGAGGGACCCCCAGTTCTCGGCTACCCCTGTCCTGGCCTCTGATGTTATCCATGCCCAATCCAGGGACCTGCCACGC
ATCTTTAGGGTGACAACCTCCCAGCTGGCAGTGCCGCCCACCACGTGCACTGTGCTGCTGCTGGCAGAGAGCGAGGGGGAGCGGGAACGC
TGGCTGCAGGTGCTGGGTGAGCTGCAGCGGCTGCTGCTGGACGCGCGGCCAAGACCCCGGCCCGTGTACACACTCAAGGAGGCTTACGAC
AACGGGCTGCCGCTGCTGCCTCACACGCTCTGCGCTGCCATCCTCGACCAGGATCGACTTGCGCTTGGCACCGAGGAGGGGCTCTTTGTC
ATCCATCTGCGCAGCAACGACATCTTCCAGGTGGGGGAGTGCCGGCGCGTGCAGCAGCTGACCTTGAGCCCCAGTGCAGGCCTGCTGGTC
GTGCTGTGTGGCCGCGGCCCCAGCGTGCGTCTCTTTGCCCTGGCGGAGCTGGAGAACATAGAGGTAGCAGGTGCCAAGATCCCCGAGTCT
CGAGGCTGCCAGGTGCTGGCAGCTGGAAGCATCCTGCAGGCCCGCACCCCGGTGCTCTGTGTAGCCGTCAAGCGCCAGGTGCTCTGCTAC
CAGCTGGGCCCGGGCCCTGGGCCCTGGCAGCGCCGCATCCGTGAGCTGCAGGCACCTGCCACTGTGCAGAGCCTGGGGCTGCTGGGCGAC
CGGCTATGTGTGGGCGCCGCCGGTGGCTTTGCACTCTACCCGCTGCTCAACGAGGCTGCGCCGTTGGCGCTGGGGGCCGGTTTGGTGCCT
GAGGAGCTGCCACCATCCCGCGGGGGCCTGGGTGAGGCACTGGGTGCCGTGGAGCTTAGCCTCAGCGAGTTCCTGCTACTCTTCACCACT
GCTGGCATCTACGTGGATGGCGCAGGCCGCAAGTCTCGTGGCCACGAGCTGTTGTGGCCAGCAGCGCCCATGGGCTGGGGGTATGCGGCC
CCCTACCTGACAGTGTTCAGCGAGAACTCCATCGATGTGTTTGACGTGAGGAGGGCAGAATGGGTGCAGACCGTGCCGCTCAAGAAGGTG
CGGCCCCTCAATCCAGAGGGCTCCCTGTTCCTCTACGGCACCGAGAAGGTCCGCCTGACCTACCTCAGGAACCAGCTGGCAGAGAAGGAC
GAGTTCGACATCCCGGACCTCACCGACAACAGCCGGCGCCAGCTGTTCCGCACCAAGAGCAAGCGCCGCTTCTTTTTCCGCGTGTCGGAG
GAGCAGCAGAAGCAGCAGCGCAGGGAGATGCTGAAGGACCCTTTTGTGCGCTCCAAGCTCATCTCGCCGCCTACCAACTTCAACCACCTA
GTACACGTGGGCCCTGCCAACGGGCGGCCCGGCGCCAGGGACAAGTCCCCGGCTCCCGAAGAGAAGGGCCGAGTTGCCCGCGGCTCCGGC
CCACAGCGGCCCCACAGCTTCTCCGAGGCGTTGCGGCGCCCAGCCTCCATGGGCAGCGAAGGCCTCGGTGGAGACGCAGACCCCATGAAG
AGGAAACCCTGGACATCCCTGTCCAGCGAGTCTGTGTCCTGCCCCCAGGGATCGCTGAGCCCTGCAACCTCCCTAATGCAGGTCTCAGAA
CGGCCCCGAAGCCTCCCCCTATCCCCTGAATTGGAGAGCTCTCCTTGATGCCCTCTGTTAGGGCCCACCCCAATCCCAGGGCAGAAGGAC
ATGAGGGAGCAAAGAGCTTGAGGAATGCCATACTCCGGCTGGTCCGGGACATGGAAATTCGGACTCAGGGAGGACCCGGGCTGGGCAATG
ACTGGGAGACTTGCCTGGGTTCCCAGGACTTGGGGGTCCTGACTCCCAGCCCTCATCCTGCCTTACCCCTCTGTTCCCAGCCCCAGCCTT
TCTAAGCCATTGGGAATAGAATGGCCCCTTTTGTTCTGGTGTCCAGGGGTGATTGTGCCAAAGCTCTTATTTCCAGTGCCAAGCCCCCAG
AGGCTTGTAAGAGTTGGGATGAGGGATGGAGAGGGACTGGGTCTCTGGGAACAGGTTGGAGGTCTTATCTGTGGACTGTCTGACTCCCAG
CTGAGGCCAAGATGGGGCATGTCCCCGTCTCTGCTTAGCGTCTGGGTGAGAAAAACAGGCTGTGATCCAGAAGAAGGGAAGATAGAGAAG
GAGGGAAAGGATGTAGGCGAAGGAGGTGAGAGACAGGATAGGAGGAAGGAAGTGGAGGAGGAGGTGATAGGAATTGGAAGGAGGTAGAAG
CCGTGCAGAGGAAGAGGGGAGAGGGACGAAGGAGGAGCGATGAAGAAGAGGAGGGAGACAAAAAGAGGGATGGAGGAGAGAGGGAGTCTG
GAGAACAAAGGGTCCTTTCTCTGGGGAGGGGTGCAGTGGGCGGGGCTGACACTGTCAGCCAATCCTCCCATCGGGGAAGAGAATCCTGGA
CAGGGACAGGATGGGGAGGGTATTTATAAGGGCTTTTTGGTGGGAGATGGGTACCCAGTGGGGGCCACTGGAGGGTCTCCGGGCACACTC
TGGCCCTTCCCAGAAAGGGGGTCGTTTTTCTCGAATCTTCAACCAGTTGTGTATTGGAAACTAGGGCGCATTTTACTATTGATCACAGTC
ATTATATTGTTATTATATTACTATTTTTATTAAACCTCCCCCCACTGAAGTGTGGGGGGCAAAATAAGTATTTATCTCCTCAAATGCCAC

>4847_4847_1_ANO1-CDC42BPG_ANO1_chr11_69951894_ENST00000316296_CDC42BPG_chr11_64606374_ENST00000342711_length(amino acids)=1480AA_BP=221
MLTRPSQVLLNSLSVDPDAECKYGLYFRDGRRKVDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGSGEPPMD
YHEDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKKMYHINETRGLLKKINSVLQKITDPIQPK
VAEHRPQTMKRLSYPFSREKQHLFDLSDKDSFFDSKTRSTIDHLQFPPDVPDVPASAQDLIRQLLCRQEERLGRGGLDDFRNHPFFEGVD
WERLASSTAPYIPELRGPMDTSNFDVDDDTLNHPGTLPPPSHGAFSGHHLPFVGFTYTSGSHSPESSSEAWAALERKLQCLEQEKVELSR
KHQEALHAPTDHRELEQLRKEVQTLRDRLPEMLRDKASLSQTDGPPAGSPGQDSDLRQELDRLHRELAEGRAGLQAQEQELCRAQGQQEE
LLQRLQEAQEREAATASQTRALSSQLEEARAAQRELEAQVSSLSRQVTQLQGQWEQRLEESSQAKTIHTASETNGMGPPEGGPQEAQLRK
EVAALREQLEQAHSHRPSGKEEALCQLQEENRRLSREQERLEAELAQEQESKQRLEGERRETESNWEAQLADILSWVNDEKVSRGYLQAL
ATKMAEELESLRNVGTQTLPARPLDHQWKARRLQKMEASARLELQSALEAEIRAKQGLQERLTQVQEAQLQAERRLQEAEKQSQALQQEL
AMLREELRARGPVDTKPSNSLIPFLSFRSSEKDSAKDPGISGEATRHGGEPDLRPEGRRSLRMGAVFPRAPTANTASTEGLPAKPGSHTL
RPRSFPSPTKCLRCTSLMLGLGRQGLGCDACGYFCHTTCAPQAPPCPVPPDLLRTALGVHPETGTGTAYEGFLSVPRPSGVRRGWQRVFA
ALSDSRLLLFDAPDLRLSPPSGALLQVLDLRDPQFSATPVLASDVIHAQSRDLPRIFRVTTSQLAVPPTTCTVLLLAESEGERERWLQVL
GELQRLLLDARPRPRPVYTLKEAYDNGLPLLPHTLCAAILDQDRLALGTEEGLFVIHLRSNDIFQVGECRRVQQLTLSPSAGLLVVLCGR
GPSVRLFALAELENIEVAGAKIPESRGCQVLAAGSILQARTPVLCVAVKRQVLCYQLGPGPGPWQRRIRELQAPATVQSLGLLGDRLCVG
AAGGFALYPLLNEAAPLALGAGLVPEELPPSRGGLGEALGAVELSLSEFLLLFTTAGIYVDGAGRKSRGHELLWPAAPMGWGYAAPYLTV
FSENSIDVFDVRRAEWVQTVPLKKVRPLNPEGSLFLYGTEKVRLTYLRNQLAEKDEFDIPDLTDNSRRQLFRTKSKRRFFFRVSEEQQKQ
QRREMLKDPFVRSKLISPPTNFNHLVHVGPANGRPGARDKSPAPEEKGRVARGSGPQRPHSFSEALRRPASMGSEGLGGDADPMKRKPWT

--------------------------------------------------------------
>4847_4847_2_ANO1-CDC42BPG_ANO1_chr11_69951894_ENST00000355303_CDC42BPG_chr11_64606374_ENST00000342711_length(transcript)=5918nt_BP=1052nt
AAAGGCGGGCCGGCTGGCGTCCAAGTTCCTGACCAGGCGCGGGCCGGCCCGCGGGACCAGCAGCCGGGTGGCGGCGCGATCGGCCCCGAG
AGGCTCAGGCGCCCCCCGCATCGAGCGCGCGGGCCGGGCGGGCCAGGGCGGCGGGCGGAGCGGGAGGCGGCCACGTCCCCGGCGGGCCTG
GGCGCGGGGAGGCCCGGCCCCCTGCGAGCGCGCCGCGAACGCTGCGGTCTCCGCCCGCAGAGGCCGCCGGGGCCGTGGATGGGGAGGGCG
CGCCGCCCGGCGGTCCCAGCGCACAGGCGGCCACGATGAGGGTCAACGAGAAGTACTCGACGCTCCCGGCCGAGGACCGCAGCGTCCACA
TCATCAACATCTGCGCCATCGAGGACATCGGCTACCTGCCGTCCGAGGGCACGCTGCTGAACTCCTTATCTGTGGACCCTGATGCCGAGT
GCAAGTATGGCCTGTACTTCAGGGACGGCCGGCGCAAGGTGGACTACATCCTGGTGTACCATCACAAGAGGCCCTCGGGCAACCGGACCC
TGGTCAGGAGGGTGCAGCACAGCGACACCCCCTCTGGGGCTCGCAGCGTCAAGCAGGACCACCCCCTGCCGGGCAAGGGGGCGTCGCTGG
ATGCAGGCTCGGGGGAGCCCCCGATGGACTACCACGAGGATGACAAGCGCTTCCGCAGGGAGGAGTACGAGGGCAACCTCCTGGAGGCGG
GCCTGGAGCTGGAGCGGGACGAGGACACTAAAATCCACGGAGTCGGGTTTGTGAAAATCCATGCCCCCTGGAACGTGCTGTGCAGAGAGG
CCGAGTTTCTGAAACTGAAGATGCCGACGAAGAAGATGTACCACATTAATGAGACCCGTGGCCTCCTGAAAAAAATCAACTCTGTGCTCC
AGAAAATCACAGATCCCATCCAGCCCAAAGTGGCTGAGCACAGGCCCCAGACCATGAAGAGACTCTCCTATCCCTTCTCCCGGGAGAAGC
AGCATCTATTTGACTTGTCTGATAAGGATTCCTTTTTCGACAGCAAAACCCGGAGCACGATTGACCACCTGCAGTTCCCCCCGGACGTGC
CTGACGTGCCAGCCAGCGCCCAAGACCTGATCCGCCAGCTGCTGTGTCGCCAGGAAGAGCGGCTAGGCCGTGGTGGGCTGGATGACTTCC
GGAACCATCCTTTCTTCGAAGGCGTGGACTGGGAGCGGCTGGCGAGCAGCACGGCCCCCTATATTCCTGAGCTGCGGGGGCCCATGGACA
CCTCCAACTTTGATGTGGATGACGACACCCTCAACCATCCAGGGACCCTGCCACCGCCCTCCCACGGGGCCTTCTCCGGCCATCACCTGC
CATTCGTGGGCTTCACCTACACCTCAGGCAGTCACAGTCCTGAGAGCAGCTCTGAGGCTTGGGCTGCCCTGGAGCGGAAGCTCCAGTGTC
TGGAGCAGGAGAAGGTGGAGCTGAGCAGGAAGCACCAAGAGGCCCTGCACGCCCCCACAGACCATCGGGAGCTGGAGCAGCTACGGAAGG
AAGTGCAGACTCTGCGGGACAGGCTGCCAGAGATGCTGAGGGACAAGGCCTCATTGTCCCAGACGGATGGGCCCCCAGCTGGTAGCCCAG
GTCAGGACAGTGACCTACGGCAGGAGCTTGACCGACTTCACCGGGAGCTGGCCGAGGGTCGGGCAGGGCTGCAGGCTCAGGAGCAGGAGC
TCTGCAGGGCCCAGGGGCAGCAGGAGGAGCTGCTTCAGAGGCTACAGGAGGCCCAGGAGAGAGAGGCGGCCACAGCTAGCCAGACCCGGG
CCCTGAGCTCCCAGCTGGAGGAAGCCCGGGCTGCCCAGAGGGAGCTGGAGGCCCAGGTGTCCTCCCTGAGCCGGCAGGTGACGCAGCTGC
AGGGACAGTGGGAGCAACGCCTTGAGGAGTCGTCCCAGGCCAAGACCATCCACACAGCCTCTGAGACCAACGGGATGGGACCCCCTGAGG
GTGGGCCTCAGGAGGCCCAACTGAGGAAGGAGGTGGCCGCCCTGCGAGAGCAGCTGGAGCAGGCCCACAGCCACAGGCCGAGTGGTAAGG
AGGAGGCTCTGTGCCAGCTGCAGGAGGAAAACCGGAGGCTGAGCCGGGAGCAGGAGCGGCTAGAAGCAGAGCTGGCCCAGGAGCAGGAGA
GCAAGCAGCGGCTGGAGGGTGAGCGGCGGGAGACGGAGAGCAACTGGGAGGCCCAGCTCGCCGACATCCTCAGCTGGGTGAATGATGAGA
AGGTCTCAAGAGGCTACCTGCAGGCCCTGGCCACCAAGATGGCAGAGGAGCTGGAGTCCTTGAGGAACGTAGGCACCCAGACGCTCCCTG
CCCGGCCACTGGACCACCAGTGGAAGGCGCGGCGACTGCAGAAGATGGAGGCCTCGGCCAGGCTGGAGCTGCAGTCAGCGCTGGAGGCCG
AGATCCGCGCCAAGCAGGGCCTGCAGGAGCGGCTGACACAGGTGCAGGAGGCCCAGCTGCAGGCTGAGCGCCGTCTGCAGGAGGCCGAGA
AGCAGAGCCAGGCCCTGCAACAGGAGCTCGCCATGCTGCGGGAGGAGCTGCGGGCCCGAGGGCCAGTGGACACCAAGCCCTCAAACTCCC
TGATTCCCTTCCTGTCCTTCCGGAGCTCAGAGAAGGATTCTGCCAAGGACCCTGGCATCTCAGGAGAGGCCACAAGGCATGGAGGAGAGC
CAGATCTGAGGCCGGAGGGCCGACGCAGCCTGCGCATGGGGGCTGTGTTCCCCAGAGCACCCACTGCCAACACAGCCTCTACAGAAGGTC
TTCCTGCTAAGCCCGGCTCACACACGCTGCGCCCCCGGAGCTTCCCATCCCCGACCAAGTGTCTCCGCTGCACCTCGCTGATGCTGGGCC
TGGGCCGCCAGGGCCTGGGTTGTGATGCCTGCGGCTACTTTTGTCACACAACCTGTGCCCCACAGGCCCCACCCTGCCCCGTGCCCCCTG
ACCTCCTCCGCACAGCCCTGGGAGTACACCCCGAAACAGGCACAGGCACTGCCTATGAGGGCTTTCTGTCGGTGCCGCGGCCCTCAGGTG
TCCGGCGGGGCTGGCAGCGCGTGTTTGCTGCCCTGAGTGACTCACGCCTGCTGCTGTTTGACGCCCCTGACCTGAGGCTCAGCCCGCCCA
GTGGGGCCCTCCTGCAGGTCCTAGATCTGAGGGACCCCCAGTTCTCGGCTACCCCTGTCCTGGCCTCTGATGTTATCCATGCCCAATCCA
GGGACCTGCCACGCATCTTTAGGGTGACAACCTCCCAGCTGGCAGTGCCGCCCACCACGTGCACTGTGCTGCTGCTGGCAGAGAGCGAGG
GGGAGCGGGAACGCTGGCTGCAGGTGCTGGGTGAGCTGCAGCGGCTGCTGCTGGACGCGCGGCCAAGACCCCGGCCCGTGTACACACTCA
AGGAGGCTTACGACAACGGGCTGCCGCTGCTGCCTCACACGCTCTGCGCTGCCATCCTCGACCAGGATCGACTTGCGCTTGGCACCGAGG
AGGGGCTCTTTGTCATCCATCTGCGCAGCAACGACATCTTCCAGGTGGGGGAGTGCCGGCGCGTGCAGCAGCTGACCTTGAGCCCCAGTG
CAGGCCTGCTGGTCGTGCTGTGTGGCCGCGGCCCCAGCGTGCGTCTCTTTGCCCTGGCGGAGCTGGAGAACATAGAGGTAGCAGGTGCCA
AGATCCCCGAGTCTCGAGGCTGCCAGGTGCTGGCAGCTGGAAGCATCCTGCAGGCCCGCACCCCGGTGCTCTGTGTAGCCGTCAAGCGCC
AGGTGCTCTGCTACCAGCTGGGCCCGGGCCCTGGGCCCTGGCAGCGCCGCATCCGTGAGCTGCAGGCACCTGCCACTGTGCAGAGCCTGG
GGCTGCTGGGCGACCGGCTATGTGTGGGCGCCGCCGGTGGCTTTGCACTCTACCCGCTGCTCAACGAGGCTGCGCCGTTGGCGCTGGGGG
CCGGTTTGGTGCCTGAGGAGCTGCCACCATCCCGCGGGGGCCTGGGTGAGGCACTGGGTGCCGTGGAGCTTAGCCTCAGCGAGTTCCTGC
TACTCTTCACCACTGCTGGCATCTACGTGGATGGCGCAGGCCGCAAGTCTCGTGGCCACGAGCTGTTGTGGCCAGCAGCGCCCATGGGCT
GGGGGTATGCGGCCCCCTACCTGACAGTGTTCAGCGAGAACTCCATCGATGTGTTTGACGTGAGGAGGGCAGAATGGGTGCAGACCGTGC
CGCTCAAGAAGGTGCGGCCCCTCAATCCAGAGGGCTCCCTGTTCCTCTACGGCACCGAGAAGGTCCGCCTGACCTACCTCAGGAACCAGC
TGGCAGAGAAGGACGAGTTCGACATCCCGGACCTCACCGACAACAGCCGGCGCCAGCTGTTCCGCACCAAGAGCAAGCGCCGCTTCTTTT
TCCGCGTGTCGGAGGAGCAGCAGAAGCAGCAGCGCAGGGAGATGCTGAAGGACCCTTTTGTGCGCTCCAAGCTCATCTCGCCGCCTACCA
ACTTCAACCACCTAGTACACGTGGGCCCTGCCAACGGGCGGCCCGGCGCCAGGGACAAGTCCCCGGCTCCCGAAGAGAAGGGCCGAGTTG
CCCGCGGCTCCGGCCCACAGCGGCCCCACAGCTTCTCCGAGGCGTTGCGGCGCCCAGCCTCCATGGGCAGCGAAGGCCTCGGTGGAGACG
CAGACCCCATGAAGAGGAAACCCTGGACATCCCTGTCCAGCGAGTCTGTGTCCTGCCCCCAGGGATCGCTGAGCCCTGCAACCTCCCTAA
TGCAGGTCTCAGAACGGCCCCGAAGCCTCCCCCTATCCCCTGAATTGGAGAGCTCTCCTTGATGCCCTCTGTTAGGGCCCACCCCAATCC
CAGGGCAGAAGGACATGAGGGAGCAAAGAGCTTGAGGAATGCCATACTCCGGCTGGTCCGGGACATGGAAATTCGGACTCAGGGAGGACC
CGGGCTGGGCAATGACTGGGAGACTTGCCTGGGTTCCCAGGACTTGGGGGTCCTGACTCCCAGCCCTCATCCTGCCTTACCCCTCTGTTC
CCAGCCCCAGCCTTTCTAAGCCATTGGGAATAGAATGGCCCCTTTTGTTCTGGTGTCCAGGGGTGATTGTGCCAAAGCTCTTATTTCCAG
TGCCAAGCCCCCAGAGGCTTGTAAGAGTTGGGATGAGGGATGGAGAGGGACTGGGTCTCTGGGAACAGGTTGGAGGTCTTATCTGTGGAC
TGTCTGACTCCCAGCTGAGGCCAAGATGGGGCATGTCCCCGTCTCTGCTTAGCGTCTGGGTGAGAAAAACAGGCTGTGATCCAGAAGAAG
GGAAGATAGAGAAGGAGGGAAAGGATGTAGGCGAAGGAGGTGAGAGACAGGATAGGAGGAAGGAAGTGGAGGAGGAGGTGATAGGAATTG
GAAGGAGGTAGAAGCCGTGCAGAGGAAGAGGGGAGAGGGACGAAGGAGGAGCGATGAAGAAGAGGAGGGAGACAAAAAGAGGGATGGAGG
AGAGAGGGAGTCTGGAGAACAAAGGGTCCTTTCTCTGGGGAGGGGTGCAGTGGGCGGGGCTGACACTGTCAGCCAATCCTCCCATCGGGG
AAGAGAATCCTGGACAGGGACAGGATGGGGAGGGTATTTATAAGGGCTTTTTGGTGGGAGATGGGTACCCAGTGGGGGCCACTGGAGGGT
CTCCGGGCACACTCTGGCCCTTCCCAGAAAGGGGGTCGTTTTTCTCGAATCTTCAACCAGTTGTGTATTGGAAACTAGGGCGCATTTTAC
TATTGATCACAGTCATTATATTGTTATTATATTACTATTTTTATTAAACCTCCCCCCACTGAAGTGTGGGGGGCAAAATAAGTATTTATC

>4847_4847_2_ANO1-CDC42BPG_ANO1_chr11_69951894_ENST00000355303_CDC42BPG_chr11_64606374_ENST00000342711_length(amino acids)=1536AA_BP=277
MRSPPAEAAGAVDGEGAPPGGPSAQAATMRVNEKYSTLPAEDRSVHIINICAIEDIGYLPSEGTLLNSLSVDPDAECKYGLYFRDGRRKV
DYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGSGEPPMDYHEDDKRFRREEYEGNLLEAGLELERDEDTKIHG
VGFVKIHAPWNVLCREAEFLKLKMPTKKMYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSFFD
SKTRSTIDHLQFPPDVPDVPASAQDLIRQLLCRQEERLGRGGLDDFRNHPFFEGVDWERLASSTAPYIPELRGPMDTSNFDVDDDTLNHP
GTLPPPSHGAFSGHHLPFVGFTYTSGSHSPESSSEAWAALERKLQCLEQEKVELSRKHQEALHAPTDHRELEQLRKEVQTLRDRLPEMLR
DKASLSQTDGPPAGSPGQDSDLRQELDRLHRELAEGRAGLQAQEQELCRAQGQQEELLQRLQEAQEREAATASQTRALSSQLEEARAAQR
ELEAQVSSLSRQVTQLQGQWEQRLEESSQAKTIHTASETNGMGPPEGGPQEAQLRKEVAALREQLEQAHSHRPSGKEEALCQLQEENRRL
SREQERLEAELAQEQESKQRLEGERRETESNWEAQLADILSWVNDEKVSRGYLQALATKMAEELESLRNVGTQTLPARPLDHQWKARRLQ
KMEASARLELQSALEAEIRAKQGLQERLTQVQEAQLQAERRLQEAEKQSQALQQELAMLREELRARGPVDTKPSNSLIPFLSFRSSEKDS
AKDPGISGEATRHGGEPDLRPEGRRSLRMGAVFPRAPTANTASTEGLPAKPGSHTLRPRSFPSPTKCLRCTSLMLGLGRQGLGCDACGYF
CHTTCAPQAPPCPVPPDLLRTALGVHPETGTGTAYEGFLSVPRPSGVRRGWQRVFAALSDSRLLLFDAPDLRLSPPSGALLQVLDLRDPQ
FSATPVLASDVIHAQSRDLPRIFRVTTSQLAVPPTTCTVLLLAESEGERERWLQVLGELQRLLLDARPRPRPVYTLKEAYDNGLPLLPHT
LCAAILDQDRLALGTEEGLFVIHLRSNDIFQVGECRRVQQLTLSPSAGLLVVLCGRGPSVRLFALAELENIEVAGAKIPESRGCQVLAAG
SILQARTPVLCVAVKRQVLCYQLGPGPGPWQRRIRELQAPATVQSLGLLGDRLCVGAAGGFALYPLLNEAAPLALGAGLVPEELPPSRGG
LGEALGAVELSLSEFLLLFTTAGIYVDGAGRKSRGHELLWPAAPMGWGYAAPYLTVFSENSIDVFDVRRAEWVQTVPLKKVRPLNPEGSL
FLYGTEKVRLTYLRNQLAEKDEFDIPDLTDNSRRQLFRTKSKRRFFFRVSEEQQKQQRREMLKDPFVRSKLISPPTNFNHLVHVGPANGR
PGARDKSPAPEEKGRVARGSGPQRPHSFSEALRRPASMGSEGLGGDADPMKRKPWTSLSSESVSCPQGSLSPATSLMQVSERPRSLPLSP

--------------------------------------------------------------
>4847_4847_3_ANO1-CDC42BPG_ANO1_chr11_69951894_ENST00000398543_CDC42BPG_chr11_64606374_ENST00000342711_length(transcript)=5662nt_BP=796nt
GGATGGGGAGGGCGCGCCGCCCGGCGGTCCCAGCGCACAGGCGGCCACGATGAGGGTCAACGAGAAGTACTCGACGCTCCCGGCCGAGGA
CCGCAGCGTCCACATCATCAACATCTGCGCCATCGAGGACATCGGCTACCTGCCGTCCGAGGGCACGCTGCTGAACTCCTTATCTGTGGA
CCCTGATGCCGAGTGCAAGTATGGCCTGTACTTCAGGGACGGCCGGCGCAAGGTGGACTACATCCTGGTGTACCATCACAAGAGGCCCTC
GGGCAACCGGACCCTGGTCAGGAGGGTGCAGCACAGCGACACCCCCTCTGGGGCTCGCAGCGTCAAGCAGGACCACCCCCTGCCGGGCAA
GGGGGCGTCGCTGGATGCAGGCTCGGGGGAGCCCCCGATGGACTACCACGAGGATGACAAGCGCTTCCGCAGGGAGGAGTACGAGGGCAA
CCTCCTGGAGGCGGGCCTGGAGCTGGAGCGGGACGAGGACACTAAAATCCACGGAGTCGGGTTTGTGAAAATCCATGCCCCCTGGAACGT
GCTGTGCAGAGAGGCCGAGTTTCTGAAACTGAAGATGCCGACGAAGAAGATGTACCACATTAATGAGACCCGTGGCCTCCTGAAAAAAAT
CAACTCTGTGCTCCAGAAAATCACAGATCCCATCCAGCCCAAAGTGGCTGAGCACAGGCCCCAGACCATGAAGAGACTCTCCTATCCCTT
CTCCCGGGAGAAGCAGCATCTATTTGACTTGTCTGATAAGGATTCCTTTTTCGACAGCAAAACCCGGAGCACGATTGACCACCTGCAGTT
CCCCCCGGACGTGCCTGACGTGCCAGCCAGCGCCCAAGACCTGATCCGCCAGCTGCTGTGTCGCCAGGAAGAGCGGCTAGGCCGTGGTGG
GCTGGATGACTTCCGGAACCATCCTTTCTTCGAAGGCGTGGACTGGGAGCGGCTGGCGAGCAGCACGGCCCCCTATATTCCTGAGCTGCG
GGGGCCCATGGACACCTCCAACTTTGATGTGGATGACGACACCCTCAACCATCCAGGGACCCTGCCACCGCCCTCCCACGGGGCCTTCTC
CGGCCATCACCTGCCATTCGTGGGCTTCACCTACACCTCAGGCAGTCACAGTCCTGAGAGCAGCTCTGAGGCTTGGGCTGCCCTGGAGCG
GAAGCTCCAGTGTCTGGAGCAGGAGAAGGTGGAGCTGAGCAGGAAGCACCAAGAGGCCCTGCACGCCCCCACAGACCATCGGGAGCTGGA
GCAGCTACGGAAGGAAGTGCAGACTCTGCGGGACAGGCTGCCAGAGATGCTGAGGGACAAGGCCTCATTGTCCCAGACGGATGGGCCCCC
AGCTGGTAGCCCAGGTCAGGACAGTGACCTACGGCAGGAGCTTGACCGACTTCACCGGGAGCTGGCCGAGGGTCGGGCAGGGCTGCAGGC
TCAGGAGCAGGAGCTCTGCAGGGCCCAGGGGCAGCAGGAGGAGCTGCTTCAGAGGCTACAGGAGGCCCAGGAGAGAGAGGCGGCCACAGC
TAGCCAGACCCGGGCCCTGAGCTCCCAGCTGGAGGAAGCCCGGGCTGCCCAGAGGGAGCTGGAGGCCCAGGTGTCCTCCCTGAGCCGGCA
GGTGACGCAGCTGCAGGGACAGTGGGAGCAACGCCTTGAGGAGTCGTCCCAGGCCAAGACCATCCACACAGCCTCTGAGACCAACGGGAT
GGGACCCCCTGAGGGTGGGCCTCAGGAGGCCCAACTGAGGAAGGAGGTGGCCGCCCTGCGAGAGCAGCTGGAGCAGGCCCACAGCCACAG
GCCGAGTGGTAAGGAGGAGGCTCTGTGCCAGCTGCAGGAGGAAAACCGGAGGCTGAGCCGGGAGCAGGAGCGGCTAGAAGCAGAGCTGGC
CCAGGAGCAGGAGAGCAAGCAGCGGCTGGAGGGTGAGCGGCGGGAGACGGAGAGCAACTGGGAGGCCCAGCTCGCCGACATCCTCAGCTG
GGTGAATGATGAGAAGGTCTCAAGAGGCTACCTGCAGGCCCTGGCCACCAAGATGGCAGAGGAGCTGGAGTCCTTGAGGAACGTAGGCAC
CCAGACGCTCCCTGCCCGGCCACTGGACCACCAGTGGAAGGCGCGGCGACTGCAGAAGATGGAGGCCTCGGCCAGGCTGGAGCTGCAGTC
AGCGCTGGAGGCCGAGATCCGCGCCAAGCAGGGCCTGCAGGAGCGGCTGACACAGGTGCAGGAGGCCCAGCTGCAGGCTGAGCGCCGTCT
GCAGGAGGCCGAGAAGCAGAGCCAGGCCCTGCAACAGGAGCTCGCCATGCTGCGGGAGGAGCTGCGGGCCCGAGGGCCAGTGGACACCAA
GCCCTCAAACTCCCTGATTCCCTTCCTGTCCTTCCGGAGCTCAGAGAAGGATTCTGCCAAGGACCCTGGCATCTCAGGAGAGGCCACAAG
GCATGGAGGAGAGCCAGATCTGAGGCCGGAGGGCCGACGCAGCCTGCGCATGGGGGCTGTGTTCCCCAGAGCACCCACTGCCAACACAGC
CTCTACAGAAGGTCTTCCTGCTAAGCCCGGCTCACACACGCTGCGCCCCCGGAGCTTCCCATCCCCGACCAAGTGTCTCCGCTGCACCTC
GCTGATGCTGGGCCTGGGCCGCCAGGGCCTGGGTTGTGATGCCTGCGGCTACTTTTGTCACACAACCTGTGCCCCACAGGCCCCACCCTG
CCCCGTGCCCCCTGACCTCCTCCGCACAGCCCTGGGAGTACACCCCGAAACAGGCACAGGCACTGCCTATGAGGGCTTTCTGTCGGTGCC
GCGGCCCTCAGGTGTCCGGCGGGGCTGGCAGCGCGTGTTTGCTGCCCTGAGTGACTCACGCCTGCTGCTGTTTGACGCCCCTGACCTGAG
GCTCAGCCCGCCCAGTGGGGCCCTCCTGCAGGTCCTAGATCTGAGGGACCCCCAGTTCTCGGCTACCCCTGTCCTGGCCTCTGATGTTAT
CCATGCCCAATCCAGGGACCTGCCACGCATCTTTAGGGTGACAACCTCCCAGCTGGCAGTGCCGCCCACCACGTGCACTGTGCTGCTGCT
GGCAGAGAGCGAGGGGGAGCGGGAACGCTGGCTGCAGGTGCTGGGTGAGCTGCAGCGGCTGCTGCTGGACGCGCGGCCAAGACCCCGGCC
CGTGTACACACTCAAGGAGGCTTACGACAACGGGCTGCCGCTGCTGCCTCACACGCTCTGCGCTGCCATCCTCGACCAGGATCGACTTGC
GCTTGGCACCGAGGAGGGGCTCTTTGTCATCCATCTGCGCAGCAACGACATCTTCCAGGTGGGGGAGTGCCGGCGCGTGCAGCAGCTGAC
CTTGAGCCCCAGTGCAGGCCTGCTGGTCGTGCTGTGTGGCCGCGGCCCCAGCGTGCGTCTCTTTGCCCTGGCGGAGCTGGAGAACATAGA
GGTAGCAGGTGCCAAGATCCCCGAGTCTCGAGGCTGCCAGGTGCTGGCAGCTGGAAGCATCCTGCAGGCCCGCACCCCGGTGCTCTGTGT
AGCCGTCAAGCGCCAGGTGCTCTGCTACCAGCTGGGCCCGGGCCCTGGGCCCTGGCAGCGCCGCATCCGTGAGCTGCAGGCACCTGCCAC
TGTGCAGAGCCTGGGGCTGCTGGGCGACCGGCTATGTGTGGGCGCCGCCGGTGGCTTTGCACTCTACCCGCTGCTCAACGAGGCTGCGCC
GTTGGCGCTGGGGGCCGGTTTGGTGCCTGAGGAGCTGCCACCATCCCGCGGGGGCCTGGGTGAGGCACTGGGTGCCGTGGAGCTTAGCCT
CAGCGAGTTCCTGCTACTCTTCACCACTGCTGGCATCTACGTGGATGGCGCAGGCCGCAAGTCTCGTGGCCACGAGCTGTTGTGGCCAGC
AGCGCCCATGGGCTGGGGGTATGCGGCCCCCTACCTGACAGTGTTCAGCGAGAACTCCATCGATGTGTTTGACGTGAGGAGGGCAGAATG
GGTGCAGACCGTGCCGCTCAAGAAGGTGCGGCCCCTCAATCCAGAGGGCTCCCTGTTCCTCTACGGCACCGAGAAGGTCCGCCTGACCTA
CCTCAGGAACCAGCTGGCAGAGAAGGACGAGTTCGACATCCCGGACCTCACCGACAACAGCCGGCGCCAGCTGTTCCGCACCAAGAGCAA
GCGCCGCTTCTTTTTCCGCGTGTCGGAGGAGCAGCAGAAGCAGCAGCGCAGGGAGATGCTGAAGGACCCTTTTGTGCGCTCCAAGCTCAT
CTCGCCGCCTACCAACTTCAACCACCTAGTACACGTGGGCCCTGCCAACGGGCGGCCCGGCGCCAGGGACAAGTCCCCGGCTCCCGAAGA
GAAGGGCCGAGTTGCCCGCGGCTCCGGCCCACAGCGGCCCCACAGCTTCTCCGAGGCGTTGCGGCGCCCAGCCTCCATGGGCAGCGAAGG
CCTCGGTGGAGACGCAGACCCCATGAAGAGGAAACCCTGGACATCCCTGTCCAGCGAGTCTGTGTCCTGCCCCCAGGGATCGCTGAGCCC
TGCAACCTCCCTAATGCAGGTCTCAGAACGGCCCCGAAGCCTCCCCCTATCCCCTGAATTGGAGAGCTCTCCTTGATGCCCTCTGTTAGG
GCCCACCCCAATCCCAGGGCAGAAGGACATGAGGGAGCAAAGAGCTTGAGGAATGCCATACTCCGGCTGGTCCGGGACATGGAAATTCGG
ACTCAGGGAGGACCCGGGCTGGGCAATGACTGGGAGACTTGCCTGGGTTCCCAGGACTTGGGGGTCCTGACTCCCAGCCCTCATCCTGCC
TTACCCCTCTGTTCCCAGCCCCAGCCTTTCTAAGCCATTGGGAATAGAATGGCCCCTTTTGTTCTGGTGTCCAGGGGTGATTGTGCCAAA
GCTCTTATTTCCAGTGCCAAGCCCCCAGAGGCTTGTAAGAGTTGGGATGAGGGATGGAGAGGGACTGGGTCTCTGGGAACAGGTTGGAGG
TCTTATCTGTGGACTGTCTGACTCCCAGCTGAGGCCAAGATGGGGCATGTCCCCGTCTCTGCTTAGCGTCTGGGTGAGAAAAACAGGCTG
TGATCCAGAAGAAGGGAAGATAGAGAAGGAGGGAAAGGATGTAGGCGAAGGAGGTGAGAGACAGGATAGGAGGAAGGAAGTGGAGGAGGA
GGTGATAGGAATTGGAAGGAGGTAGAAGCCGTGCAGAGGAAGAGGGGAGAGGGACGAAGGAGGAGCGATGAAGAAGAGGAGGGAGACAAA
AAGAGGGATGGAGGAGAGAGGGAGTCTGGAGAACAAAGGGTCCTTTCTCTGGGGAGGGGTGCAGTGGGCGGGGCTGACACTGTCAGCCAA
TCCTCCCATCGGGGAAGAGAATCCTGGACAGGGACAGGATGGGGAGGGTATTTATAAGGGCTTTTTGGTGGGAGATGGGTACCCAGTGGG
GGCCACTGGAGGGTCTCCGGGCACACTCTGGCCCTTCCCAGAAAGGGGGTCGTTTTTCTCGAATCTTCAACCAGTTGTGTATTGGAAACT
AGGGCGCATTTTACTATTGATCACAGTCATTATATTGTTATTATATTACTATTTTTATTAAACCTCCCCCCACTGAAGTGTGGGGGGCAA

>4847_4847_3_ANO1-CDC42BPG_ANO1_chr11_69951894_ENST00000398543_CDC42BPG_chr11_64606374_ENST00000342711_length(amino acids)=1508AA_BP=249
MRVNEKYSTLPAEDRSVHIINICAIEDIGYLPSEGTLLNSLSVDPDAECKYGLYFRDGRRKVDYILVYHHKRPSGNRTLVRRVQHSDTPS
GARSVKQDHPLPGKGASLDAGSGEPPMDYHEDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKK
MYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSFFDSKTRSTIDHLQFPPDVPDVPASAQDLIR
QLLCRQEERLGRGGLDDFRNHPFFEGVDWERLASSTAPYIPELRGPMDTSNFDVDDDTLNHPGTLPPPSHGAFSGHHLPFVGFTYTSGSH
SPESSSEAWAALERKLQCLEQEKVELSRKHQEALHAPTDHRELEQLRKEVQTLRDRLPEMLRDKASLSQTDGPPAGSPGQDSDLRQELDR
LHRELAEGRAGLQAQEQELCRAQGQQEELLQRLQEAQEREAATASQTRALSSQLEEARAAQRELEAQVSSLSRQVTQLQGQWEQRLEESS
QAKTIHTASETNGMGPPEGGPQEAQLRKEVAALREQLEQAHSHRPSGKEEALCQLQEENRRLSREQERLEAELAQEQESKQRLEGERRET
ESNWEAQLADILSWVNDEKVSRGYLQALATKMAEELESLRNVGTQTLPARPLDHQWKARRLQKMEASARLELQSALEAEIRAKQGLQERL
TQVQEAQLQAERRLQEAEKQSQALQQELAMLREELRARGPVDTKPSNSLIPFLSFRSSEKDSAKDPGISGEATRHGGEPDLRPEGRRSLR
MGAVFPRAPTANTASTEGLPAKPGSHTLRPRSFPSPTKCLRCTSLMLGLGRQGLGCDACGYFCHTTCAPQAPPCPVPPDLLRTALGVHPE
TGTGTAYEGFLSVPRPSGVRRGWQRVFAALSDSRLLLFDAPDLRLSPPSGALLQVLDLRDPQFSATPVLASDVIHAQSRDLPRIFRVTTS
QLAVPPTTCTVLLLAESEGERERWLQVLGELQRLLLDARPRPRPVYTLKEAYDNGLPLLPHTLCAAILDQDRLALGTEEGLFVIHLRSND
IFQVGECRRVQQLTLSPSAGLLVVLCGRGPSVRLFALAELENIEVAGAKIPESRGCQVLAAGSILQARTPVLCVAVKRQVLCYQLGPGPG
PWQRRIRELQAPATVQSLGLLGDRLCVGAAGGFALYPLLNEAAPLALGAGLVPEELPPSRGGLGEALGAVELSLSEFLLLFTTAGIYVDG
AGRKSRGHELLWPAAPMGWGYAAPYLTVFSENSIDVFDVRRAEWVQTVPLKKVRPLNPEGSLFLYGTEKVRLTYLRNQLAEKDEFDIPDL
TDNSRRQLFRTKSKRRFFFRVSEEQQKQQRREMLKDPFVRSKLISPPTNFNHLVHVGPANGRPGARDKSPAPEEKGRVARGSGPQRPHSF

--------------------------------------------------------------
>4847_4847_4_ANO1-CDC42BPG_ANO1_chr11_69951894_ENST00000530676_CDC42BPG_chr11_64606374_ENST00000342711_length(transcript)=5754nt_BP=888nt
TGAGTCCAGGTCCTCCTGAAGGTCACCAGCACAGCGGGGCCCTGTGTTACTGTAGAGAGAAGTCAGTTGCTTAGTTTCAGCCTCCTGCCG
GCACCAGATGCTGACCAGGCCCTCCCAGGTGGTGAGCAATGCTGTTTCCAGGAGAGGCATCCTAGGGCCAGAGAGGCCAAGGTGCCAGGG
ACATGGCCCCAACTGTCCCCTAACCAGGGGTAGAGGAGTCTAGACCCTTGACATCAACACCTATGAAAGCTGCTGAACTCCTTATCTGTG
GACCCTGATGCCGAGTGCAAGTATGGCCTGTACTTCAGGGACGGCCGGCGCAAGGTGGACTACATCCTGGTGTACCATCACAAGAGGCCC
TCGGGCAACCGGACCCTGGTCAGGAGGGTGCAGCACAGCGACACCCCCTCTGGGGCTCGCAGCGTCAAGCAGGACCACCCCCTGCCGGGC
AAGGGGGCGTCGCTGGATGCAGGCTCGGGGGAGCCCCCGATGGACTACCACGAGGATGACAAGCGCTTCCGCAGGGAGGAGTACGAGGGC
AACCTCCTGGAGGCGGGCCTGGAGCTGGAGCGGGACGAGGACACTAAAATCCACGGAGTCGGGTTTGTGAAAATCCATGCCCCCTGGAAC
GTGCTGTGCAGAGAGGCCGAGTTTCTGAAACTGAAGATGCCGACGAAGAAGATGTACCACATTAATGAGACCCGTGGCCTCCTGAAAAAA
ATCAACTCTGTGCTCCAGAAAATCACAGATCCCATCCAGCCCAAAGTGGCTGAGCACAGGCCCCAGACCATGAAGAGACTCTCCTATCCC
TTCTCCCGGGAGAAGCAGCATCTATTTGACTTGTCTGATAAGGATTCCTTTTTCGACAGCAAAACCCGGAGCACGATTGACCACCTGCAG
TTCCCCCCGGACGTGCCTGACGTGCCAGCCAGCGCCCAAGACCTGATCCGCCAGCTGCTGTGTCGCCAGGAAGAGCGGCTAGGCCGTGGT
GGGCTGGATGACTTCCGGAACCATCCTTTCTTCGAAGGCGTGGACTGGGAGCGGCTGGCGAGCAGCACGGCCCCCTATATTCCTGAGCTG
CGGGGGCCCATGGACACCTCCAACTTTGATGTGGATGACGACACCCTCAACCATCCAGGGACCCTGCCACCGCCCTCCCACGGGGCCTTC
TCCGGCCATCACCTGCCATTCGTGGGCTTCACCTACACCTCAGGCAGTCACAGTCCTGAGAGCAGCTCTGAGGCTTGGGCTGCCCTGGAG
CGGAAGCTCCAGTGTCTGGAGCAGGAGAAGGTGGAGCTGAGCAGGAAGCACCAAGAGGCCCTGCACGCCCCCACAGACCATCGGGAGCTG
GAGCAGCTACGGAAGGAAGTGCAGACTCTGCGGGACAGGCTGCCAGAGATGCTGAGGGACAAGGCCTCATTGTCCCAGACGGATGGGCCC
CCAGCTGGTAGCCCAGGTCAGGACAGTGACCTACGGCAGGAGCTTGACCGACTTCACCGGGAGCTGGCCGAGGGTCGGGCAGGGCTGCAG
GCTCAGGAGCAGGAGCTCTGCAGGGCCCAGGGGCAGCAGGAGGAGCTGCTTCAGAGGCTACAGGAGGCCCAGGAGAGAGAGGCGGCCACA
GCTAGCCAGACCCGGGCCCTGAGCTCCCAGCTGGAGGAAGCCCGGGCTGCCCAGAGGGAGCTGGAGGCCCAGGTGTCCTCCCTGAGCCGG
CAGGTGACGCAGCTGCAGGGACAGTGGGAGCAACGCCTTGAGGAGTCGTCCCAGGCCAAGACCATCCACACAGCCTCTGAGACCAACGGG
ATGGGACCCCCTGAGGGTGGGCCTCAGGAGGCCCAACTGAGGAAGGAGGTGGCCGCCCTGCGAGAGCAGCTGGAGCAGGCCCACAGCCAC
AGGCCGAGTGGTAAGGAGGAGGCTCTGTGCCAGCTGCAGGAGGAAAACCGGAGGCTGAGCCGGGAGCAGGAGCGGCTAGAAGCAGAGCTG
GCCCAGGAGCAGGAGAGCAAGCAGCGGCTGGAGGGTGAGCGGCGGGAGACGGAGAGCAACTGGGAGGCCCAGCTCGCCGACATCCTCAGC
TGGGTGAATGATGAGAAGGTCTCAAGAGGCTACCTGCAGGCCCTGGCCACCAAGATGGCAGAGGAGCTGGAGTCCTTGAGGAACGTAGGC
ACCCAGACGCTCCCTGCCCGGCCACTGGACCACCAGTGGAAGGCGCGGCGACTGCAGAAGATGGAGGCCTCGGCCAGGCTGGAGCTGCAG
TCAGCGCTGGAGGCCGAGATCCGCGCCAAGCAGGGCCTGCAGGAGCGGCTGACACAGGTGCAGGAGGCCCAGCTGCAGGCTGAGCGCCGT
CTGCAGGAGGCCGAGAAGCAGAGCCAGGCCCTGCAACAGGAGCTCGCCATGCTGCGGGAGGAGCTGCGGGCCCGAGGGCCAGTGGACACC
AAGCCCTCAAACTCCCTGATTCCCTTCCTGTCCTTCCGGAGCTCAGAGAAGGATTCTGCCAAGGACCCTGGCATCTCAGGAGAGGCCACA
AGGCATGGAGGAGAGCCAGATCTGAGGCCGGAGGGCCGACGCAGCCTGCGCATGGGGGCTGTGTTCCCCAGAGCACCCACTGCCAACACA
GCCTCTACAGAAGGTCTTCCTGCTAAGCCCGGCTCACACACGCTGCGCCCCCGGAGCTTCCCATCCCCGACCAAGTGTCTCCGCTGCACC
TCGCTGATGCTGGGCCTGGGCCGCCAGGGCCTGGGTTGTGATGCCTGCGGCTACTTTTGTCACACAACCTGTGCCCCACAGGCCCCACCC
TGCCCCGTGCCCCCTGACCTCCTCCGCACAGCCCTGGGAGTACACCCCGAAACAGGCACAGGCACTGCCTATGAGGGCTTTCTGTCGGTG
CCGCGGCCCTCAGGTGTCCGGCGGGGCTGGCAGCGCGTGTTTGCTGCCCTGAGTGACTCACGCCTGCTGCTGTTTGACGCCCCTGACCTG
AGGCTCAGCCCGCCCAGTGGGGCCCTCCTGCAGGTCCTAGATCTGAGGGACCCCCAGTTCTCGGCTACCCCTGTCCTGGCCTCTGATGTT
ATCCATGCCCAATCCAGGGACCTGCCACGCATCTTTAGGGTGACAACCTCCCAGCTGGCAGTGCCGCCCACCACGTGCACTGTGCTGCTG
CTGGCAGAGAGCGAGGGGGAGCGGGAACGCTGGCTGCAGGTGCTGGGTGAGCTGCAGCGGCTGCTGCTGGACGCGCGGCCAAGACCCCGG
CCCGTGTACACACTCAAGGAGGCTTACGACAACGGGCTGCCGCTGCTGCCTCACACGCTCTGCGCTGCCATCCTCGACCAGGATCGACTT
GCGCTTGGCACCGAGGAGGGGCTCTTTGTCATCCATCTGCGCAGCAACGACATCTTCCAGGTGGGGGAGTGCCGGCGCGTGCAGCAGCTG
ACCTTGAGCCCCAGTGCAGGCCTGCTGGTCGTGCTGTGTGGCCGCGGCCCCAGCGTGCGTCTCTTTGCCCTGGCGGAGCTGGAGAACATA
GAGGTAGCAGGTGCCAAGATCCCCGAGTCTCGAGGCTGCCAGGTGCTGGCAGCTGGAAGCATCCTGCAGGCCCGCACCCCGGTGCTCTGT
GTAGCCGTCAAGCGCCAGGTGCTCTGCTACCAGCTGGGCCCGGGCCCTGGGCCCTGGCAGCGCCGCATCCGTGAGCTGCAGGCACCTGCC
ACTGTGCAGAGCCTGGGGCTGCTGGGCGACCGGCTATGTGTGGGCGCCGCCGGTGGCTTTGCACTCTACCCGCTGCTCAACGAGGCTGCG
CCGTTGGCGCTGGGGGCCGGTTTGGTGCCTGAGGAGCTGCCACCATCCCGCGGGGGCCTGGGTGAGGCACTGGGTGCCGTGGAGCTTAGC
CTCAGCGAGTTCCTGCTACTCTTCACCACTGCTGGCATCTACGTGGATGGCGCAGGCCGCAAGTCTCGTGGCCACGAGCTGTTGTGGCCA
GCAGCGCCCATGGGCTGGGGGTATGCGGCCCCCTACCTGACAGTGTTCAGCGAGAACTCCATCGATGTGTTTGACGTGAGGAGGGCAGAA
TGGGTGCAGACCGTGCCGCTCAAGAAGGTGCGGCCCCTCAATCCAGAGGGCTCCCTGTTCCTCTACGGCACCGAGAAGGTCCGCCTGACC
TACCTCAGGAACCAGCTGGCAGAGAAGGACGAGTTCGACATCCCGGACCTCACCGACAACAGCCGGCGCCAGCTGTTCCGCACCAAGAGC
AAGCGCCGCTTCTTTTTCCGCGTGTCGGAGGAGCAGCAGAAGCAGCAGCGCAGGGAGATGCTGAAGGACCCTTTTGTGCGCTCCAAGCTC
ATCTCGCCGCCTACCAACTTCAACCACCTAGTACACGTGGGCCCTGCCAACGGGCGGCCCGGCGCCAGGGACAAGTCCCCGGCTCCCGAA
GAGAAGGGCCGAGTTGCCCGCGGCTCCGGCCCACAGCGGCCCCACAGCTTCTCCGAGGCGTTGCGGCGCCCAGCCTCCATGGGCAGCGAA
GGCCTCGGTGGAGACGCAGACCCCATGAAGAGGAAACCCTGGACATCCCTGTCCAGCGAGTCTGTGTCCTGCCCCCAGGGATCGCTGAGC
CCTGCAACCTCCCTAATGCAGGTCTCAGAACGGCCCCGAAGCCTCCCCCTATCCCCTGAATTGGAGAGCTCTCCTTGATGCCCTCTGTTA
GGGCCCACCCCAATCCCAGGGCAGAAGGACATGAGGGAGCAAAGAGCTTGAGGAATGCCATACTCCGGCTGGTCCGGGACATGGAAATTC
GGACTCAGGGAGGACCCGGGCTGGGCAATGACTGGGAGACTTGCCTGGGTTCCCAGGACTTGGGGGTCCTGACTCCCAGCCCTCATCCTG
CCTTACCCCTCTGTTCCCAGCCCCAGCCTTTCTAAGCCATTGGGAATAGAATGGCCCCTTTTGTTCTGGTGTCCAGGGGTGATTGTGCCA
AAGCTCTTATTTCCAGTGCCAAGCCCCCAGAGGCTTGTAAGAGTTGGGATGAGGGATGGAGAGGGACTGGGTCTCTGGGAACAGGTTGGA
GGTCTTATCTGTGGACTGTCTGACTCCCAGCTGAGGCCAAGATGGGGCATGTCCCCGTCTCTGCTTAGCGTCTGGGTGAGAAAAACAGGC
TGTGATCCAGAAGAAGGGAAGATAGAGAAGGAGGGAAAGGATGTAGGCGAAGGAGGTGAGAGACAGGATAGGAGGAAGGAAGTGGAGGAG
GAGGTGATAGGAATTGGAAGGAGGTAGAAGCCGTGCAGAGGAAGAGGGGAGAGGGACGAAGGAGGAGCGATGAAGAAGAGGAGGGAGACA
AAAAGAGGGATGGAGGAGAGAGGGAGTCTGGAGAACAAAGGGTCCTTTCTCTGGGGAGGGGTGCAGTGGGCGGGGCTGACACTGTCAGCC
AATCCTCCCATCGGGGAAGAGAATCCTGGACAGGGACAGGATGGGGAGGGTATTTATAAGGGCTTTTTGGTGGGAGATGGGTACCCAGTG
GGGGCCACTGGAGGGTCTCCGGGCACACTCTGGCCCTTCCCAGAAAGGGGGTCGTTTTTCTCGAATCTTCAACCAGTTGTGTATTGGAAA
CTAGGGCGCATTTTACTATTGATCACAGTCATTATATTGTTATTATATTACTATTTTTATTAAACCTCCCCCCACTGAAGTGTGGGGGGC

>4847_4847_4_ANO1-CDC42BPG_ANO1_chr11_69951894_ENST00000530676_CDC42BPG_chr11_64606374_ENST00000342711_length(amino acids)=1472AA_BP=213
MLNSLSVDPDAECKYGLYFRDGRRKVDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGSGEPPMDYHEDDKRF
RREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKKMYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQT
MKRLSYPFSREKQHLFDLSDKDSFFDSKTRSTIDHLQFPPDVPDVPASAQDLIRQLLCRQEERLGRGGLDDFRNHPFFEGVDWERLASST
APYIPELRGPMDTSNFDVDDDTLNHPGTLPPPSHGAFSGHHLPFVGFTYTSGSHSPESSSEAWAALERKLQCLEQEKVELSRKHQEALHA
PTDHRELEQLRKEVQTLRDRLPEMLRDKASLSQTDGPPAGSPGQDSDLRQELDRLHRELAEGRAGLQAQEQELCRAQGQQEELLQRLQEA
QEREAATASQTRALSSQLEEARAAQRELEAQVSSLSRQVTQLQGQWEQRLEESSQAKTIHTASETNGMGPPEGGPQEAQLRKEVAALREQ
LEQAHSHRPSGKEEALCQLQEENRRLSREQERLEAELAQEQESKQRLEGERRETESNWEAQLADILSWVNDEKVSRGYLQALATKMAEEL
ESLRNVGTQTLPARPLDHQWKARRLQKMEASARLELQSALEAEIRAKQGLQERLTQVQEAQLQAERRLQEAEKQSQALQQELAMLREELR
ARGPVDTKPSNSLIPFLSFRSSEKDSAKDPGISGEATRHGGEPDLRPEGRRSLRMGAVFPRAPTANTASTEGLPAKPGSHTLRPRSFPSP
TKCLRCTSLMLGLGRQGLGCDACGYFCHTTCAPQAPPCPVPPDLLRTALGVHPETGTGTAYEGFLSVPRPSGVRRGWQRVFAALSDSRLL
LFDAPDLRLSPPSGALLQVLDLRDPQFSATPVLASDVIHAQSRDLPRIFRVTTSQLAVPPTTCTVLLLAESEGERERWLQVLGELQRLLL
DARPRPRPVYTLKEAYDNGLPLLPHTLCAAILDQDRLALGTEEGLFVIHLRSNDIFQVGECRRVQQLTLSPSAGLLVVLCGRGPSVRLFA
LAELENIEVAGAKIPESRGCQVLAAGSILQARTPVLCVAVKRQVLCYQLGPGPGPWQRRIRELQAPATVQSLGLLGDRLCVGAAGGFALY
PLLNEAAPLALGAGLVPEELPPSRGGLGEALGAVELSLSEFLLLFTTAGIYVDGAGRKSRGHELLWPAAPMGWGYAAPYLTVFSENSIDV
FDVRRAEWVQTVPLKKVRPLNPEGSLFLYGTEKVRLTYLRNQLAEKDEFDIPDLTDNSRRQLFRTKSKRRFFFRVSEEQQKQQRREMLKD
PFVRSKLISPPTNFNHLVHVGPANGRPGARDKSPAPEEKGRVARGSGPQRPHSFSEALRRPASMGSEGLGGDADPMKRKPWTSLSSESVS

--------------------------------------------------------------
>4847_4847_5_ANO1-CDC42BPG_ANO1_chr11_69951894_ENST00000538023_CDC42BPG_chr11_64606374_ENST00000342711_length(transcript)=5662nt_BP=796nt
GGATGGGGAGGGCGCGCCGCCCGGCGGTCCCAGCGCACAGGCGGCCACGATGAGGGTCAACGAGAAGTACTCGACGCTCCCGGCCGAGGA
CCGCAGCGTCCACATCATCAACATCTGCGCCATCGAGGACATCGGCTACCTGCCGTCCGAGGGCACGCTGCTGAACTCCTTATCTGTGGA
CCCTGATGCCGAGTGCAAGTATGGCCTGTACTTCAGGGACGGCCGGCGCAAGGTGGACTACATCCTGGTGTACCATCACAAGAGGCCCTC
GGGCAACCGGACCCTGGTCAGGAGGGTGCAGCACAGCGACACCCCCTCTGGGGCTCGCAGCGTCAAGCAGGACCACCCCCTGCCGGGCAA
GGGGGCGTCGCTGGATGCAGGCTCGGGGGAGCCCCCGATGGACTACCACGAGGATGACAAGCGCTTCCGCAGGGAGGAGTACGAGGGCAA
CCTCCTGGAGGCGGGCCTGGAGCTGGAGCGGGACGAGGACACTAAAATCCACGGAGTCGGGTTTGTGAAAATCCATGCCCCCTGGAACGT
GCTGTGCAGAGAGGCCGAGTTTCTGAAACTGAAGATGCCGACGAAGAAGATGTACCACATTAATGAGACCCGTGGCCTCCTGAAAAAAAT
CAACTCTGTGCTCCAGAAAATCACAGATCCCATCCAGCCCAAAGTGGCTGAGCACAGGCCCCAGACCATGAAGAGACTCTCCTATCCCTT
CTCCCGGGAGAAGCAGCATCTATTTGACTTGTCTGATAAGGATTCCTTTTTCGACAGCAAAACCCGGAGCACGATTGACCACCTGCAGTT
CCCCCCGGACGTGCCTGACGTGCCAGCCAGCGCCCAAGACCTGATCCGCCAGCTGCTGTGTCGCCAGGAAGAGCGGCTAGGCCGTGGTGG
GCTGGATGACTTCCGGAACCATCCTTTCTTCGAAGGCGTGGACTGGGAGCGGCTGGCGAGCAGCACGGCCCCCTATATTCCTGAGCTGCG
GGGGCCCATGGACACCTCCAACTTTGATGTGGATGACGACACCCTCAACCATCCAGGGACCCTGCCACCGCCCTCCCACGGGGCCTTCTC
CGGCCATCACCTGCCATTCGTGGGCTTCACCTACACCTCAGGCAGTCACAGTCCTGAGAGCAGCTCTGAGGCTTGGGCTGCCCTGGAGCG
GAAGCTCCAGTGTCTGGAGCAGGAGAAGGTGGAGCTGAGCAGGAAGCACCAAGAGGCCCTGCACGCCCCCACAGACCATCGGGAGCTGGA
GCAGCTACGGAAGGAAGTGCAGACTCTGCGGGACAGGCTGCCAGAGATGCTGAGGGACAAGGCCTCATTGTCCCAGACGGATGGGCCCCC
AGCTGGTAGCCCAGGTCAGGACAGTGACCTACGGCAGGAGCTTGACCGACTTCACCGGGAGCTGGCCGAGGGTCGGGCAGGGCTGCAGGC
TCAGGAGCAGGAGCTCTGCAGGGCCCAGGGGCAGCAGGAGGAGCTGCTTCAGAGGCTACAGGAGGCCCAGGAGAGAGAGGCGGCCACAGC
TAGCCAGACCCGGGCCCTGAGCTCCCAGCTGGAGGAAGCCCGGGCTGCCCAGAGGGAGCTGGAGGCCCAGGTGTCCTCCCTGAGCCGGCA
GGTGACGCAGCTGCAGGGACAGTGGGAGCAACGCCTTGAGGAGTCGTCCCAGGCCAAGACCATCCACACAGCCTCTGAGACCAACGGGAT
GGGACCCCCTGAGGGTGGGCCTCAGGAGGCCCAACTGAGGAAGGAGGTGGCCGCCCTGCGAGAGCAGCTGGAGCAGGCCCACAGCCACAG
GCCGAGTGGTAAGGAGGAGGCTCTGTGCCAGCTGCAGGAGGAAAACCGGAGGCTGAGCCGGGAGCAGGAGCGGCTAGAAGCAGAGCTGGC
CCAGGAGCAGGAGAGCAAGCAGCGGCTGGAGGGTGAGCGGCGGGAGACGGAGAGCAACTGGGAGGCCCAGCTCGCCGACATCCTCAGCTG
GGTGAATGATGAGAAGGTCTCAAGAGGCTACCTGCAGGCCCTGGCCACCAAGATGGCAGAGGAGCTGGAGTCCTTGAGGAACGTAGGCAC
CCAGACGCTCCCTGCCCGGCCACTGGACCACCAGTGGAAGGCGCGGCGACTGCAGAAGATGGAGGCCTCGGCCAGGCTGGAGCTGCAGTC
AGCGCTGGAGGCCGAGATCCGCGCCAAGCAGGGCCTGCAGGAGCGGCTGACACAGGTGCAGGAGGCCCAGCTGCAGGCTGAGCGCCGTCT
GCAGGAGGCCGAGAAGCAGAGCCAGGCCCTGCAACAGGAGCTCGCCATGCTGCGGGAGGAGCTGCGGGCCCGAGGGCCAGTGGACACCAA
GCCCTCAAACTCCCTGATTCCCTTCCTGTCCTTCCGGAGCTCAGAGAAGGATTCTGCCAAGGACCCTGGCATCTCAGGAGAGGCCACAAG
GCATGGAGGAGAGCCAGATCTGAGGCCGGAGGGCCGACGCAGCCTGCGCATGGGGGCTGTGTTCCCCAGAGCACCCACTGCCAACACAGC
CTCTACAGAAGGTCTTCCTGCTAAGCCCGGCTCACACACGCTGCGCCCCCGGAGCTTCCCATCCCCGACCAAGTGTCTCCGCTGCACCTC
GCTGATGCTGGGCCTGGGCCGCCAGGGCCTGGGTTGTGATGCCTGCGGCTACTTTTGTCACACAACCTGTGCCCCACAGGCCCCACCCTG
CCCCGTGCCCCCTGACCTCCTCCGCACAGCCCTGGGAGTACACCCCGAAACAGGCACAGGCACTGCCTATGAGGGCTTTCTGTCGGTGCC
GCGGCCCTCAGGTGTCCGGCGGGGCTGGCAGCGCGTGTTTGCTGCCCTGAGTGACTCACGCCTGCTGCTGTTTGACGCCCCTGACCTGAG
GCTCAGCCCGCCCAGTGGGGCCCTCCTGCAGGTCCTAGATCTGAGGGACCCCCAGTTCTCGGCTACCCCTGTCCTGGCCTCTGATGTTAT
CCATGCCCAATCCAGGGACCTGCCACGCATCTTTAGGGTGACAACCTCCCAGCTGGCAGTGCCGCCCACCACGTGCACTGTGCTGCTGCT
GGCAGAGAGCGAGGGGGAGCGGGAACGCTGGCTGCAGGTGCTGGGTGAGCTGCAGCGGCTGCTGCTGGACGCGCGGCCAAGACCCCGGCC
CGTGTACACACTCAAGGAGGCTTACGACAACGGGCTGCCGCTGCTGCCTCACACGCTCTGCGCTGCCATCCTCGACCAGGATCGACTTGC
GCTTGGCACCGAGGAGGGGCTCTTTGTCATCCATCTGCGCAGCAACGACATCTTCCAGGTGGGGGAGTGCCGGCGCGTGCAGCAGCTGAC
CTTGAGCCCCAGTGCAGGCCTGCTGGTCGTGCTGTGTGGCCGCGGCCCCAGCGTGCGTCTCTTTGCCCTGGCGGAGCTGGAGAACATAGA
GGTAGCAGGTGCCAAGATCCCCGAGTCTCGAGGCTGCCAGGTGCTGGCAGCTGGAAGCATCCTGCAGGCCCGCACCCCGGTGCTCTGTGT
AGCCGTCAAGCGCCAGGTGCTCTGCTACCAGCTGGGCCCGGGCCCTGGGCCCTGGCAGCGCCGCATCCGTGAGCTGCAGGCACCTGCCAC
TGTGCAGAGCCTGGGGCTGCTGGGCGACCGGCTATGTGTGGGCGCCGCCGGTGGCTTTGCACTCTACCCGCTGCTCAACGAGGCTGCGCC
GTTGGCGCTGGGGGCCGGTTTGGTGCCTGAGGAGCTGCCACCATCCCGCGGGGGCCTGGGTGAGGCACTGGGTGCCGTGGAGCTTAGCCT
CAGCGAGTTCCTGCTACTCTTCACCACTGCTGGCATCTACGTGGATGGCGCAGGCCGCAAGTCTCGTGGCCACGAGCTGTTGTGGCCAGC
AGCGCCCATGGGCTGGGGGTATGCGGCCCCCTACCTGACAGTGTTCAGCGAGAACTCCATCGATGTGTTTGACGTGAGGAGGGCAGAATG
GGTGCAGACCGTGCCGCTCAAGAAGGTGCGGCCCCTCAATCCAGAGGGCTCCCTGTTCCTCTACGGCACCGAGAAGGTCCGCCTGACCTA
CCTCAGGAACCAGCTGGCAGAGAAGGACGAGTTCGACATCCCGGACCTCACCGACAACAGCCGGCGCCAGCTGTTCCGCACCAAGAGCAA
GCGCCGCTTCTTTTTCCGCGTGTCGGAGGAGCAGCAGAAGCAGCAGCGCAGGGAGATGCTGAAGGACCCTTTTGTGCGCTCCAAGCTCAT
CTCGCCGCCTACCAACTTCAACCACCTAGTACACGTGGGCCCTGCCAACGGGCGGCCCGGCGCCAGGGACAAGTCCCCGGCTCCCGAAGA
GAAGGGCCGAGTTGCCCGCGGCTCCGGCCCACAGCGGCCCCACAGCTTCTCCGAGGCGTTGCGGCGCCCAGCCTCCATGGGCAGCGAAGG
CCTCGGTGGAGACGCAGACCCCATGAAGAGGAAACCCTGGACATCCCTGTCCAGCGAGTCTGTGTCCTGCCCCCAGGGATCGCTGAGCCC
TGCAACCTCCCTAATGCAGGTCTCAGAACGGCCCCGAAGCCTCCCCCTATCCCCTGAATTGGAGAGCTCTCCTTGATGCCCTCTGTTAGG
GCCCACCCCAATCCCAGGGCAGAAGGACATGAGGGAGCAAAGAGCTTGAGGAATGCCATACTCCGGCTGGTCCGGGACATGGAAATTCGG
ACTCAGGGAGGACCCGGGCTGGGCAATGACTGGGAGACTTGCCTGGGTTCCCAGGACTTGGGGGTCCTGACTCCCAGCCCTCATCCTGCC
TTACCCCTCTGTTCCCAGCCCCAGCCTTTCTAAGCCATTGGGAATAGAATGGCCCCTTTTGTTCTGGTGTCCAGGGGTGATTGTGCCAAA
GCTCTTATTTCCAGTGCCAAGCCCCCAGAGGCTTGTAAGAGTTGGGATGAGGGATGGAGAGGGACTGGGTCTCTGGGAACAGGTTGGAGG
TCTTATCTGTGGACTGTCTGACTCCCAGCTGAGGCCAAGATGGGGCATGTCCCCGTCTCTGCTTAGCGTCTGGGTGAGAAAAACAGGCTG
TGATCCAGAAGAAGGGAAGATAGAGAAGGAGGGAAAGGATGTAGGCGAAGGAGGTGAGAGACAGGATAGGAGGAAGGAAGTGGAGGAGGA
GGTGATAGGAATTGGAAGGAGGTAGAAGCCGTGCAGAGGAAGAGGGGAGAGGGACGAAGGAGGAGCGATGAAGAAGAGGAGGGAGACAAA
AAGAGGGATGGAGGAGAGAGGGAGTCTGGAGAACAAAGGGTCCTTTCTCTGGGGAGGGGTGCAGTGGGCGGGGCTGACACTGTCAGCCAA
TCCTCCCATCGGGGAAGAGAATCCTGGACAGGGACAGGATGGGGAGGGTATTTATAAGGGCTTTTTGGTGGGAGATGGGTACCCAGTGGG
GGCCACTGGAGGGTCTCCGGGCACACTCTGGCCCTTCCCAGAAAGGGGGTCGTTTTTCTCGAATCTTCAACCAGTTGTGTATTGGAAACT
AGGGCGCATTTTACTATTGATCACAGTCATTATATTGTTATTATATTACTATTTTTATTAAACCTCCCCCCACTGAAGTGTGGGGGGCAA

>4847_4847_5_ANO1-CDC42BPG_ANO1_chr11_69951894_ENST00000538023_CDC42BPG_chr11_64606374_ENST00000342711_length(amino acids)=1508AA_BP=249
MRVNEKYSTLPAEDRSVHIINICAIEDIGYLPSEGTLLNSLSVDPDAECKYGLYFRDGRRKVDYILVYHHKRPSGNRTLVRRVQHSDTPS
GARSVKQDHPLPGKGASLDAGSGEPPMDYHEDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKK
MYHINETRGLLKKINSVLQKITDPIQPKVAEHRPQTMKRLSYPFSREKQHLFDLSDKDSFFDSKTRSTIDHLQFPPDVPDVPASAQDLIR
QLLCRQEERLGRGGLDDFRNHPFFEGVDWERLASSTAPYIPELRGPMDTSNFDVDDDTLNHPGTLPPPSHGAFSGHHLPFVGFTYTSGSH
SPESSSEAWAALERKLQCLEQEKVELSRKHQEALHAPTDHRELEQLRKEVQTLRDRLPEMLRDKASLSQTDGPPAGSPGQDSDLRQELDR
LHRELAEGRAGLQAQEQELCRAQGQQEELLQRLQEAQEREAATASQTRALSSQLEEARAAQRELEAQVSSLSRQVTQLQGQWEQRLEESS
QAKTIHTASETNGMGPPEGGPQEAQLRKEVAALREQLEQAHSHRPSGKEEALCQLQEENRRLSREQERLEAELAQEQESKQRLEGERRET
ESNWEAQLADILSWVNDEKVSRGYLQALATKMAEELESLRNVGTQTLPARPLDHQWKARRLQKMEASARLELQSALEAEIRAKQGLQERL
TQVQEAQLQAERRLQEAEKQSQALQQELAMLREELRARGPVDTKPSNSLIPFLSFRSSEKDSAKDPGISGEATRHGGEPDLRPEGRRSLR
MGAVFPRAPTANTASTEGLPAKPGSHTLRPRSFPSPTKCLRCTSLMLGLGRQGLGCDACGYFCHTTCAPQAPPCPVPPDLLRTALGVHPE
TGTGTAYEGFLSVPRPSGVRRGWQRVFAALSDSRLLLFDAPDLRLSPPSGALLQVLDLRDPQFSATPVLASDVIHAQSRDLPRIFRVTTS
QLAVPPTTCTVLLLAESEGERERWLQVLGELQRLLLDARPRPRPVYTLKEAYDNGLPLLPHTLCAAILDQDRLALGTEEGLFVIHLRSND
IFQVGECRRVQQLTLSPSAGLLVVLCGRGPSVRLFALAELENIEVAGAKIPESRGCQVLAAGSILQARTPVLCVAVKRQVLCYQLGPGPG
PWQRRIRELQAPATVQSLGLLGDRLCVGAAGGFALYPLLNEAAPLALGAGLVPEELPPSRGGLGEALGAVELSLSEFLLLFTTAGIYVDG
AGRKSRGHELLWPAAPMGWGYAAPYLTVFSENSIDVFDVRRAEWVQTVPLKKVRPLNPEGSLFLYGTEKVRLTYLRNQLAEKDEFDIPDL
TDNSRRQLFRTKSKRRFFFRVSEEQQKQQRREMLKDPFVRSKLISPPTNFNHLVHVGPANGRPGARDKSPAPEEKGRVARGSGPQRPHSF

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Fusion Gene PPI Analysis for ANO1-CDC42BPG


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ANO1-CDC42BPG


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ANO1-CDC42BPG


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource