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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:CASC1-ST8SIA1 (FusionGDB2 ID:HG55259TG6489) |
Fusion Gene Summary for CASC1-ST8SIA1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CASC1-ST8SIA1 | Fusion gene ID: hg55259tg6489 | Hgene | Tgene | Gene symbol | CASC1 | ST8SIA1 | Gene ID | 55259 | 6489 |
| Gene name | cancer susceptibility 1 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 | |
| Synonyms | LAS1|PPP1R54 | GD3S|SIAT8|SIAT8-A|SIAT8A|ST8SiaI | |
| Cytomap | ('CASC1')('ST8SIA1') 12p12.1 | 12p12.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | protein CASC1cancer susceptibility candidate 1cancer susceptibility candidate gene 1 proteinlung adenoma susceptibility 1-like proteinprotein phosphatase 1 regulatory subunit 54 | alpha-N-acetylneuraminide alpha-2,8-sialyltransferaseST8 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase 1alpha-2,8-sialyltransferase 8Adisialoganglioside (GD3) synthaseganglioside GD3 synthaseganglioside GT3 synthaseganglioside-specific alpha | |
| Modification date | 20200320 | 20200313 | |
| UniProtAcc | . | . | |
| Ensembl transtripts involved in fusion gene | ENST00000320267, ENST00000395987, ENST00000545133, ENST00000395990, ENST00000537577, ENST00000557684, ENST00000354189, | ||
| Fusion gene scores | * DoF score | 7 X 4 X 4=112 | 14 X 11 X 9=1386 |
| # samples | 8 | 15 | |
| ** MAII score | log2(8/112*10)=-0.485426827170242 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(15/1386*10)=-3.20789285164133 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: CASC1 [Title/Abstract] AND ST8SIA1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | CASC1(25348009)-ST8SIA1(22408323), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | CASC1-ST8SIA1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. CASC1-ST8SIA1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. CASC1-ST8SIA1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. CASC1-ST8SIA1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene breakpoints across CASC1 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across ST8SIA1 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | OV | TCGA-13-1489 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - |
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Fusion Gene ORF analysis for CASC1-ST8SIA1 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000320267 | ENST00000381424 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - |
| 5CDS-intron | ENST00000320267 | ENST00000404299 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - |
| 5CDS-intron | ENST00000320267 | ENST00000536558 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - |
| 5CDS-intron | ENST00000320267 | ENST00000539510 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - |
| 5CDS-intron | ENST00000395987 | ENST00000381424 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - |
| 5CDS-intron | ENST00000395987 | ENST00000404299 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - |
| 5CDS-intron | ENST00000395987 | ENST00000536558 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - |
| 5CDS-intron | ENST00000395987 | ENST00000539510 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - |
| 5CDS-intron | ENST00000545133 | ENST00000381424 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - |
| 5CDS-intron | ENST00000545133 | ENST00000404299 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - |
| 5CDS-intron | ENST00000545133 | ENST00000536558 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - |
| 5CDS-intron | ENST00000545133 | ENST00000539510 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - |
| 5UTR-3CDS | ENST00000395990 | ENST00000396037 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - |
| 5UTR-3CDS | ENST00000537577 | ENST00000396037 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - |
| 5UTR-3CDS | ENST00000557684 | ENST00000396037 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - |
| 5UTR-intron | ENST00000395990 | ENST00000381424 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - |
| 5UTR-intron | ENST00000395990 | ENST00000404299 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - |
| 5UTR-intron | ENST00000395990 | ENST00000536558 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - |
| 5UTR-intron | ENST00000395990 | ENST00000539510 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - |
| 5UTR-intron | ENST00000537577 | ENST00000381424 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - |
| 5UTR-intron | ENST00000537577 | ENST00000404299 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - |
| 5UTR-intron | ENST00000537577 | ENST00000536558 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - |
| 5UTR-intron | ENST00000537577 | ENST00000539510 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - |
| 5UTR-intron | ENST00000557684 | ENST00000381424 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - |
| 5UTR-intron | ENST00000557684 | ENST00000404299 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - |
| 5UTR-intron | ENST00000557684 | ENST00000536558 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - |
| 5UTR-intron | ENST00000557684 | ENST00000539510 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - |
| In-frame | ENST00000320267 | ENST00000396037 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - |
| In-frame | ENST00000395987 | ENST00000396037 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - |
| In-frame | ENST00000545133 | ENST00000396037 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - |
| intron-3CDS | ENST00000354189 | ENST00000396037 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - |
| intron-intron | ENST00000354189 | ENST00000381424 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - |
| intron-intron | ENST00000354189 | ENST00000404299 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - |
| intron-intron | ENST00000354189 | ENST00000536558 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - |
| intron-intron | ENST00000354189 | ENST00000539510 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000395987 | CASC1 | chr12 | 25348009 | - | ENST00000396037 | ST8SIA1 | chr12 | 22408323 | - | 8920 | 69 | 66 | 758 | 230 |
| ENST00000320267 | CASC1 | chr12 | 25348009 | - | ENST00000396037 | ST8SIA1 | chr12 | 22408323 | - | 8936 | 85 | 82 | 774 | 230 |
| ENST00000545133 | CASC1 | chr12 | 25348009 | - | ENST00000396037 | ST8SIA1 | chr12 | 22408323 | - | 8902 | 51 | 48 | 740 | 230 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000395987 | ENST00000396037 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - | 0.002515903 | 0.9974841 |
| ENST00000320267 | ENST00000396037 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - | 0.002507978 | 0.9974921 |
| ENST00000545133 | ENST00000396037 | CASC1 | chr12 | 25348009 | - | ST8SIA1 | chr12 | 22408323 | - | 0.002508658 | 0.99749136 |
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Fusion Genomic Features for CASC1-ST8SIA1 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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Fusion Protein Features for CASC1-ST8SIA1 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:25348009/chr12:22408323) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | . |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | ST8SIA1 | chr12:25348009 | chr12:22408323 | ENST00000396037 | 1 | 5 | 188_190 | 127 | 357.0 | Region | Substrate binding | |
| Tgene | ST8SIA1 | chr12:25348009 | chr12:22408323 | ENST00000396037 | 1 | 5 | 274_276 | 127 | 357.0 | Region | Substrate binding |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | CASC1 | chr12:25348009 | chr12:22408323 | ENST00000320267 | - | 1 | 15 | 20_88 | 1 | 717.0 | Compositional bias | Note=Glu-rich |
| Hgene | CASC1 | chr12:25348009 | chr12:22408323 | ENST00000320267 | - | 1 | 15 | 5_8 | 1 | 717.0 | Compositional bias | Note=Poly-Lys |
| Hgene | CASC1 | chr12:25348009 | chr12:22408323 | ENST00000354189 | - | 1 | 16 | 20_88 | 0 | 691.0 | Compositional bias | Note=Glu-rich |
| Hgene | CASC1 | chr12:25348009 | chr12:22408323 | ENST00000354189 | - | 1 | 16 | 5_8 | 0 | 691.0 | Compositional bias | Note=Poly-Lys |
| Hgene | CASC1 | chr12:25348009 | chr12:22408323 | ENST00000395990 | - | 1 | 17 | 20_88 | 0 | 677.0 | Compositional bias | Note=Glu-rich |
| Hgene | CASC1 | chr12:25348009 | chr12:22408323 | ENST00000395990 | - | 1 | 17 | 5_8 | 0 | 677.0 | Compositional bias | Note=Poly-Lys |
| Hgene | CASC1 | chr12:25348009 | chr12:22408323 | ENST00000545133 | - | 1 | 13 | 20_88 | 1 | 658.0 | Compositional bias | Note=Glu-rich |
| Hgene | CASC1 | chr12:25348009 | chr12:22408323 | ENST00000545133 | - | 1 | 13 | 5_8 | 1 | 658.0 | Compositional bias | Note=Poly-Lys |
| Tgene | ST8SIA1 | chr12:25348009 | chr12:22408323 | ENST00000396037 | 1 | 5 | 1_29 | 127 | 357.0 | Topological domain | Cytoplasmic | |
| Tgene | ST8SIA1 | chr12:25348009 | chr12:22408323 | ENST00000396037 | 1 | 5 | 49_356 | 127 | 357.0 | Topological domain | Lumenal | |
| Tgene | ST8SIA1 | chr12:25348009 | chr12:22408323 | ENST00000396037 | 1 | 5 | 30_48 | 127 | 357.0 | Transmembrane | Helical%3B Signal-anchor for type II membrane protein |
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Fusion Gene Sequence for CASC1-ST8SIA1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >13130_13130_1_CASC1-ST8SIA1_CASC1_chr12_25348009_ENST00000320267_ST8SIA1_chr12_22408323_ENST00000396037_length(transcript)=8936nt_BP=85nt GTCGTCCGGGCAACCCGGGAGCGTTTGTCCACACAATTTCTGCTCCGACTCTGCGGACTACTGCAGTGGAGCTTGACTCTTAATGGCAAC CCCATTCCAGCTGCCATTGAAGAAATGCGCGGTGGTGGGAAATGGTGGGATTCTGAAGAAGAGTGGCTGTGGCCGTCAAATAGATGAAGC AAATTTTGTCATGCGATGCAATCTCCCTCCTTTGTCAAGTGAATACACTAAGGATGTTGGATCCAAAAGTCAGTTAGTGACAGCTAATCC CAGCATAATTCGGCAAAGGTTTCAGAACCTTCTGTGGTCCAGAAAGACATTTGTGGACAACATGAAAATTTATAACCACAGTTACATCTA CATGCCTGCCTTTTCTATGAAGACAGGAACAGAGCCATCTTTGAGGGTTTATTATACACTGTCAGATGTTGGTGCCAATCAAACAGTGCT GTTTGCCAACCCCAACTTTCTGCGTAGCATTGGAAAGTTCTGGAAAAGTAGAGGAATCCATGCCAAGCGCCTGTCCACAGGACTTTTTCT GGTGAGCGCAGCTCTGGGTCTCTGTGAAGAGGTGGCCATCTATGGCTTCTGGCCCTTCTCTGTGAATATGCATGAGCAGCCCATCAGCCA CCACTACTATGACAACGTCTTACCCTTTTCTGGCTTCCATGCCATGCCCGAGGAATTTCTCCAACTCTGGTATCTTCATAAAATCGGTGC ACTGAGAATGCAGCTGGACCCATGTGAAGATACCTCACTCCAGCCCACTTCCTAGGAACAATGGAAGAAGAAAGGACTGAACCAGGGTAT TTTTGTTAGGTTTTCTATGTGACTCCAAGAGGGAATGGTCAAGTTGTTTCATGAGTTTGCATGGGCCCTTGGAAAAACAGGAAAGGAGCA ATGAAGATCCAAGCAAAACTTTACTTTCAGCGTTGGCTTGGAGGACAAATAAGAAATGAAACATCCTATGAAATACTTTATAGCACATGG CAGATTTGCAACTAGTAAAATGCTGGTGAAATGCTGTTGGTAAAGCACATGGTTCAAATCTAGAAGATGCAGTTCAAAAACAAGACAGAC TCGAGTTGTTAGGGCTGAGGAACCAATCAAGGTAGAACAAAGAAAATGTTGGGGTAAAAGTGTTGCTGATTGTCAACACAAACTGGCTTA ATAATATTAATAAGAACCTGTCTTATTAAGACTGGCTTTAGAACCGTAGGTTTTTTTAAAAAATTATTATTTATTTTTGCCCTCTTTGGG GAAGTGGGTGGGTAGATTTAAAAAATCCCTTCCTGAGTAATAAAGATACAAAATGTTACTGCTGATAATTGTGATTTGTTGAGCCACGTC TATATTAACTATAGCTCCCCTCTATTTTTAAAATTTTACATAAGAATTGCTTCTTCCTCTTTTGTCAAGTCCACAGAGACAATGTGAAGC ATTATTGAATTTAGACTGTGTTGCTTCATAGTCTGGATAACAGGAGCCACTTTCCTTCCTCAGAATTTAGGACATAAACCCAATTTTAGG TCTGCATTATGTAAGCCTGTTTGCATTGTCATTTTTATTTTAGTGCAAAAGACTACCAATATGAGTGAATTATTTGTTTGTAAATTGGCA TAATTGTCTTCATAATTTAATGTTCAGAAATGCAGTAAAGCACGTTGATGAAAAGCTTAGTCTCTGTGGAAGACAGACCAGAAGACAAAT CCCTTTTCTATCTACTGTGGCATATTCACTGCAAGGTAAAGGACATGTATGCATACATGCAAGAATGAATTGAGCGAAACTTTGAATATG TTTCCTCTTTTGAGCTATTGTTATTTAGTAGTTACCTAAAAAAGAATACATTTTTACTAGTATACCATTAAAAATGTAAAAGGCTTAACA TGTATGCATACATGTAGACACACATACACACACACAAAGTTAAACAAAGCTCATTACTGTGCAACTATGAAAGCTGAACTCATATGACCT GGTATGGCAAAAATTTGTAACCAGTGTTGGAGAATCACAAATGTGTTATGCACTATCCATTACATGTTGATATAAGACAACCGAGCTCAC TGGTTGCCGCACATAATACCCATAGCAGCACAAGATGCAAGTCTTACCCCCAAATGCTTACCCGGAATGAGCAGAATTGTCTTACTCATC CTGATTTTACCCAAAATCTCATGAATGGGCTTGCTGTTGAGCGTGGTCACACAAGGTATAGTTTGTACAAGTAAAGAAATGTGAATTAGT AGCTATTTATTTCCTTAGTAGCAGGTAGGACTACTTAGCTTGTTACAACAGCTTTGATACACAGTAAGAAAACTCTACTGACAGATTACA AGCAGCCAAATGTGTTTACATTTCAGAGAAGGGTAAGGGAAGCCTCTCGTTGTCTTCATACTTTGGAATGTCTTAAGCTAAAATGTGACA CTAGAGTTCAATTTCTTTTTTATTTTAAATGTCACTAAATTGTAGGTAAACTGTACCAAAAAGTTCTAGTTTAATTTTAACAGTAAAAAC TCAGCATACCATGTTACCACGTAAACAATAATGGCTGGTATTTTCTGTGGGTTAATTTAACATGACATAAACATAGGAAAGCCCTTGGCA AAATTCTACATCATTGAAGTAGACCATTTCTAAATGCAATTAAATAGTGAGGTTATTATAAAAATTAGAATTTAAAATATGACTTGTTGA TAGTGCAGATTATAATGTTACTTAGAAAGTTAAGAATTCGAGAGTAATGATGCTATTGGAGAACTGGTTTGCTATACGGCAGCAAAAACA TAATGAGAATGTACCATGAAGAAATTGTGTTAAATATTCACTTTGAGTGAAACTTTAAATATGTTTCCTCTTTTGAGCTACTGTTATTTA GCAGTTACCTAAAAAAGAATACATTTTTACTAGTCTACCATTAAAAATATAAAAGGCTTAACAAAAACGCATATAAAAGTTAATAAAATG TTACTCAGATTAGTACTTTAATTGTTAAAATGTAATTAATGAGCTCCATAGAGCCCATACATCACAGTTCCATTGAAAATATCATCTGGA CTAGAATCTCTTAAACCCAGGAAGTGGAGGTTGCAGTGAGCCAAGATGGTGCCACTGCACTCCAGCCTGGGTGACAGGGCAAGACCCTGT CTCAAAAAAAAAAAAAAGAAAAGAAAAAGAAAGAAAATATTATGTGGAAATTTTTCATCTTTTTATGATGCCTGGGATAGATTTATGCAG TAGATTTATATATAATGTTTAGTTTACAAACTTGTGAAACTATTTCATGTGGGTTCTGAAAGGCAAAACAGAAATGGCCAGTGCTGGTGA TGTTTGATTAGACCAGCTCTTCTCAGCTGGGGTGATTCATTATCCCTCTCTGGTGACATTTGGCAATGTCTGGAGACCAGAGACATTTTT TATTTTCATGACTCAAGGGTGCTAATAGCATGTACTTAGTAGAGGTTAGGGATCCTGCTAAAGATCTTACAATGCACAAGTCAGCCTCTC ACAGCAAAATAATTATCCAGGCTGAGATGTCAGTAGTATCAAGGTTGACATCTCAGACCTGGATTAGACCTGGATTAGACCAAAATGAAA TTTTGATTGTTCCACCTTGTCTTCACTTAAAGATAGATATACATGCTCACAGCATTCAAAATATGACTACAATTTAATGAAAATATTTTC TTATGGTAGATTACAACTCACTAGATACACCATACATATGCCTTTTGGACATAATTGGTTAGATAGGAGTGTGTGTGTGTGTGTGTGTGT GTGTGTGTGTGTGTGTGTGTGTGTAGCATGAAGTTAGGCATCTCTATCCTTAACTGTGCTATGTGTTCCTAAGTAAGGACCTCGCTAGAA TCATCCTGTAGAGTGCTCTGGAATACTCTATTATTAAGATCTTCAATTCTAAGCTCCCATTATCTTTCTTTGTTTATCTGAAATTAAGAC CTTCAGAATTAGGCCTGGTACTTTTCCAGATTTGATCAGTTACATTTTGATATAACTGACTCTTAAAATTCAGCTTAGAAGACATTCAAT AAGAAAATCTTTAATCACTTTTGGTGATGCACCTGCCAAGAGGGGGCATCACTTTGTACCATCAGACTAATTAAAAAAATTGTTGTGTAG TCATAAAAATTAGGCTGATCCATAGGGGCAAAAGGAAGGGTGAAGAGACTAAAAACTAGTACCCTGATAGAATTTTAGTTTTTATTAGCC TCGATTTGAGAACTGCATTGATTCCAAAGATCATGAAGGTAGGTGAAGGATTAAGTCATTCCATAATTAAGAAAAGTAATGTTTATATGA AAGATTTTTATATGGACAATGACTCACAGACACATATGCTTTGTATAGAGGATTTTGCCAAAAGTTTATACAAAATTGCACATCTAAACT GCATAATTCTCATACAAGAAGTTAAGGAAGTGCTCACTGGATTTTGCTTCTGTATAGTTCACTTTTATCTGTCTTCACAAGGGTAGGAAG TAAATGATCTCAAATGGCACATGTTCAGACAATACTGTGTTTGGCTTTGTGATGTCTCATGTCTTTCTCTTGGCTAAAAAAAATTGTTTA GGCTATATATAACTTGTACCTGAAGCAATCTGGACAACATGGCTTAAAATGGAAAATAACTGAAAAAATCCTGGGATTTTAAATTTGCCA AAAATACCCTTGGATTAGTCAAAGGCTTTACAAGAGTGTTATAGATGATCCAAAATGGAAACAATATTGATAACATTTCTTTTCGTCAGC AGCTACATATTCCAGTTTTATAACTTTATTATATACATTTTTTGATTATTAATAGAAAGTCAGCCATCCAGAGTTTTAACTTCTGTGGTT GAAATATTGACTTTGTGAAATTTTTCACTGACAAATACTTGTTAGGAGGGACCTAAGGGGGAGGGGAATGTTACCAGTCCACTGAAAACT TTAGGAAATGTTCATTGTGTTGTGTAAATACTTTCCCACCAGCACCAGGTAATATATTCTCTATGTTTGTAGAATTCCAAAGATCAAAAG CTGTAAGGACGTTTATGTGAACTTGACGCAAACTTGTGGAGGAATAAGGACTGAGAGTAATGTTGTGCTTTTTCTTTATCTTCCCGTCGT ATAGGTCGACTCTCAGGTTATATGACTTTTATTGGGCACACGTCAGGGGTGGAAGTGGTAGAAGTGGGTTAACAATTTCAAGGCCTGGCA ACCTAGGTCAAAACCTCTAATAAAGTCAGCAGTAAACATAACTAGCAACTTCATTCCACTATGTGCTAGGAGGAGGGTGAGGCAAGTTGA AAGGAGATGACCCTATCCCCACACTCTCAGGATGTAAAAGGGCAGAGTGCTCTCTACCCTTAACCTTGGCTTTTTAGCACCGTCAGTCTC TGTCCTCTCCCAGGAGAGCTGCCTTGGCTCCAGAGTTGAGCTAGTAGCATTGTGACTAGAGAGGTAGTGTGGAAATTCGCTGAGGACCTC AAAATTTTACACTGCCTTAAACTGTTTTGTTTTTGCTTAAACTCGTGCTGTCTAAATGTGGGTGTTTTGTGGCAGAGTCTGATCACCCCG ACCTAGTTATAGCCCTGCCAGTGATTCTAAAGTGGAACTTTTCCCCCTCATTCATATGGATAGTCTGAGTCCTTGAAGCTAGGGAGATAT CAAATATTCTACCAGTTCCTACATAGCTTCTTTAAAAGTCCTAGAGACTAACTCACAGGAAGTCTGAAGCCCAGAGCGTCTGTTTATAAA CTCCTAAATATGAGGCCACAATATTTAGGTTGAGCACTAGAAAATTTCTATTTTGCAAGTGGAAGGAGACTTGAATCTATAATTGCTGTA GCTTTTTTTCCCTTCTATCATAAGAAAATGGATACCATCTGCTTTACCCTCAGCCCAGACTTGTCTTTTGAATTTTTTACATACATCTTA GGGGTGAGAGATTGAAACAAGTGCATGAATGAAAAGCTTATTGAAACATAACACAGCCCCTGCTCACCATTTCAGTAAGGGAAAATACAT GTTTCTGTTTCCCTCTAATTTGTTTTCTCTGGTGCCAACATTTCTGATTTCTTCTGTCTCTAATACATAAGGAATAAATACCATATTTTA AATTGACTTACATGCCTGCGAGCATTTGCCAGATAATCAAAGCCTATGACTCTAACTTTTTAAAGCACAGAAGAGGAATTATATTTTATG GTCACTCCTCTGTGTTTCTATTGATCTCTATATTGTGCTAAAATTCTTTCAGGTAATTTTTTTCTTGTTGAAGCTGTGGGATATAATCAA TGATGCCAAGCTGTCTGAGAATTTTATAGAATAATATCCAAATATATTGATCCTGCCTCTTTCTGCTTCTATGTAATTAAACTTTCTTTT GATGTTTATTTTTAAAATGTATGCTTCACACAACACCAATAAACATCTAAGAGATGTGATATAATCCAAGGCAAAGAAAAGTAAGAATCA GTTAATGTCTATTTTATCTGCACAGCATTACGAACAGAAAATTGTAATAAAAAAAGGTTTAACCAAACTGAAAAAAAGAGAGACAAAATC TTGGTTTTAATTTGAAAAGATGATTGGGAGTGATCTCAGAAGAGAGTTCAGCAGGAAGCAAGGAAGAGGCTGTTGACCTTGAGTGCAGCC TCAAGAATGGAACCTTTTTGAAATATTTTAAAGGAAATATCTTGTCATCCAGCTGTTATGGTTAATAATGAATAGTTTTCTCTGGGTGAA GCTTATCCATTGCACACCTGATGTGCTGGCCCCTGCGATTTCCCCAAATGTTGGAATGTTGCCTGCATAATTTGTGGTAATGGGGGACTG TGTTCCTGCTTTTACCTGGTTACAAAAAACAAAACAAAACAAAACAAAACAACAAACAGAAAAAAAAAGAGAGAAAAGATGCTAGAGGAA GCAGTGTGACAGACAGATCATGAGATGCTGACGGAGAGAACAGAGTGGTACCTGTTTACCCACTTGGACCATGACAGTATCAAGGCTCCA CCCCTTGCTGTCCCTTCCCAAGAGGTGCTCTCCTGGGAGTTTGATCACAGTGAAACAACACTCCCGTTTTCTTTTTCCTTTCTTTCTTTC TTTCTTTTTTTTTTTTTTTTTTTTTTTTGTTGAGACAGAGTTTTTTGCTCTTGTTGCCCAGGCTGGAGTGCAATGGCGTGATCTCGGCTC ACCGCAACCTCCGCCTCCCAGGTTCAAGCGATTCTCGTGCCTCAGCCTCTGGAGTAGCTGGGATTACAGGCATGCGCCACCACACCCGGC TAATTTTGTACTTTTAGTAGAGATGGGGTTTCTCCATATTGGTCAGGCTGGTCCCGAACTCCTGACCTCAGGTGATCTGCCCGCCTCAGC CTCCCAAAGTGCTGGGATTACAGGCATAAGCCACCGAGCCCAGCCCCACACTCCTGTTTTCATAGCCCTTTTTTGTCTGTACTTTGGTAC ATATTCCCCAAATAAGATTATTATTTACATCTGTCATGATGAGGCAGTGATAGCAGCAAGTGTCACTTTGACCCTCACCCTTGGAAAGTG GGCTATGCATAGCTAGAGTTAGAACAGGAGGTTCTAATCCTGCTTCCACAATTACTTCAGTAACAGGCTTTTGTATCCATGATTACTTAA GCTGACTTAGATGCATTTTCTACCCTGTATTCTAGTGTACACAACACAAACACACATAAGCCCTTTACCTGTGGAGAAGAGGGAGATGGT TGATTCAGTGGGAGTGGGGAGTGGCAGAGGGTGCCTTAACTTTTTCTGGCTTGACCCCTACTTCCTTATGTGTTTCCTTCATATACCTCT GTCACTTTAGAGATGTAATCATGTCTGTTCCAAGTTGTATCGTTATTATCAAGAAGTCCTATAAATGTAGCAAATGTGACTATTTTATAG AAATGCACAATAGTTTATAGGCCTTGGAGAAGTCTGATAATAGTATGTAAATATCCTTCATTGAAGTCATAGAACCTTCTAGTAGGAAGC TCCATAGGTGATAACTGCAAGAGGATTAATGTTTGTTTCTCCAGTAAACACCGGAAGCAAGGAATCAATCTGTCACTGTTTATCATTCAG TCTTGAGCACCGTTGGGTGTTGATAGGTTACTATAGACACTCCCCTTATAATTAATATACAGGACTCACAATTTAGGATGTCTGATGGCC ACTAGGGTACATCATAGAGACACTAGAGAGAAGAGAACAAATATAGCTCCATCAAAAAGCCTGCTTAATCTTTAACAAGTCTGAAATATT ACTAAAATTCCAGTTACCGTGCAGCATAGTCAGTCTAAAAAGCACTGGGGAAAAAGGTGTCTTTTTGGTCTCTTTAATTCTATTATGGCA CATTTTAATATTATTCCACATGTGTGCAAACTATTTCTCAAGAGCAAAGTTTGAGGCTGGAGTTAAGAAAATAGAAAAATTAAAACATTA TTTTTTCTCATATAATATAATCTGACTACTAGTTCATGGATATAATAATTCTGGGAAAAATTTTAGATTAAACTATAAAATTGAAATCAC CTTTGAAGAGTATATGGAATTGCTTCTTTCTATTAAAGCCAACCTACATTGGCAAAAAGTGTGGAGAAAATCAGTGTGCTCAATTCTTTT TGTAGAGTTTCATCTAAAATGTTGCAGGTAAAAAAGAAAACTTTAATTGGTACTTTCTACGGTGTGATTAGAAAAATTAGTATCTATCTC TGTTGGTTCTGCTGACTTGCTTCTTTCCACCGAATCTAAATGCAATGTCATAGGAGGAGGTTTGCTGTAAAAACATGTCTTTTTCTTTGG TGTATTCATTGTAATTATGGCTGGCAGTGAGAAGGTTCGGTAAGTCTCAATTTCTCTACCTCCTTTACTTGGAGAAAATTTGTAAATGTA >13130_13130_1_CASC1-ST8SIA1_CASC1_chr12_25348009_ENST00000320267_ST8SIA1_chr12_22408323_ENST00000396037_length(amino acids)=230AA_BP=1 MATPFQLPLKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQLVTANPSIIRQRFQNLLWSRKTFVDNMKIYNHS YIYMPAFSMKTGTEPSLRVYYTLSDVGANQTVLFANPNFLRSIGKFWKSRGIHAKRLSTGLFLVSAALGLCEEVAIYGFWPFSVNMHEQP -------------------------------------------------------------- >13130_13130_2_CASC1-ST8SIA1_CASC1_chr12_25348009_ENST00000395987_ST8SIA1_chr12_22408323_ENST00000396037_length(transcript)=8920nt_BP=69nt GGGAGCGTTTGTCCACACAATTTCTGCTCCGACTCTGCGGACTACTGCAGTGGAGCTTGACTCTTAATGGCAACCCCATTCCAGCTGCCA TTGAAGAAATGCGCGGTGGTGGGAAATGGTGGGATTCTGAAGAAGAGTGGCTGTGGCCGTCAAATAGATGAAGCAAATTTTGTCATGCGA TGCAATCTCCCTCCTTTGTCAAGTGAATACACTAAGGATGTTGGATCCAAAAGTCAGTTAGTGACAGCTAATCCCAGCATAATTCGGCAA AGGTTTCAGAACCTTCTGTGGTCCAGAAAGACATTTGTGGACAACATGAAAATTTATAACCACAGTTACATCTACATGCCTGCCTTTTCT ATGAAGACAGGAACAGAGCCATCTTTGAGGGTTTATTATACACTGTCAGATGTTGGTGCCAATCAAACAGTGCTGTTTGCCAACCCCAAC TTTCTGCGTAGCATTGGAAAGTTCTGGAAAAGTAGAGGAATCCATGCCAAGCGCCTGTCCACAGGACTTTTTCTGGTGAGCGCAGCTCTG GGTCTCTGTGAAGAGGTGGCCATCTATGGCTTCTGGCCCTTCTCTGTGAATATGCATGAGCAGCCCATCAGCCACCACTACTATGACAAC GTCTTACCCTTTTCTGGCTTCCATGCCATGCCCGAGGAATTTCTCCAACTCTGGTATCTTCATAAAATCGGTGCACTGAGAATGCAGCTG GACCCATGTGAAGATACCTCACTCCAGCCCACTTCCTAGGAACAATGGAAGAAGAAAGGACTGAACCAGGGTATTTTTGTTAGGTTTTCT ATGTGACTCCAAGAGGGAATGGTCAAGTTGTTTCATGAGTTTGCATGGGCCCTTGGAAAAACAGGAAAGGAGCAATGAAGATCCAAGCAA AACTTTACTTTCAGCGTTGGCTTGGAGGACAAATAAGAAATGAAACATCCTATGAAATACTTTATAGCACATGGCAGATTTGCAACTAGT AAAATGCTGGTGAAATGCTGTTGGTAAAGCACATGGTTCAAATCTAGAAGATGCAGTTCAAAAACAAGACAGACTCGAGTTGTTAGGGCT GAGGAACCAATCAAGGTAGAACAAAGAAAATGTTGGGGTAAAAGTGTTGCTGATTGTCAACACAAACTGGCTTAATAATATTAATAAGAA CCTGTCTTATTAAGACTGGCTTTAGAACCGTAGGTTTTTTTAAAAAATTATTATTTATTTTTGCCCTCTTTGGGGAAGTGGGTGGGTAGA TTTAAAAAATCCCTTCCTGAGTAATAAAGATACAAAATGTTACTGCTGATAATTGTGATTTGTTGAGCCACGTCTATATTAACTATAGCT CCCCTCTATTTTTAAAATTTTACATAAGAATTGCTTCTTCCTCTTTTGTCAAGTCCACAGAGACAATGTGAAGCATTATTGAATTTAGAC TGTGTTGCTTCATAGTCTGGATAACAGGAGCCACTTTCCTTCCTCAGAATTTAGGACATAAACCCAATTTTAGGTCTGCATTATGTAAGC CTGTTTGCATTGTCATTTTTATTTTAGTGCAAAAGACTACCAATATGAGTGAATTATTTGTTTGTAAATTGGCATAATTGTCTTCATAAT TTAATGTTCAGAAATGCAGTAAAGCACGTTGATGAAAAGCTTAGTCTCTGTGGAAGACAGACCAGAAGACAAATCCCTTTTCTATCTACT GTGGCATATTCACTGCAAGGTAAAGGACATGTATGCATACATGCAAGAATGAATTGAGCGAAACTTTGAATATGTTTCCTCTTTTGAGCT ATTGTTATTTAGTAGTTACCTAAAAAAGAATACATTTTTACTAGTATACCATTAAAAATGTAAAAGGCTTAACATGTATGCATACATGTA GACACACATACACACACACAAAGTTAAACAAAGCTCATTACTGTGCAACTATGAAAGCTGAACTCATATGACCTGGTATGGCAAAAATTT GTAACCAGTGTTGGAGAATCACAAATGTGTTATGCACTATCCATTACATGTTGATATAAGACAACCGAGCTCACTGGTTGCCGCACATAA TACCCATAGCAGCACAAGATGCAAGTCTTACCCCCAAATGCTTACCCGGAATGAGCAGAATTGTCTTACTCATCCTGATTTTACCCAAAA TCTCATGAATGGGCTTGCTGTTGAGCGTGGTCACACAAGGTATAGTTTGTACAAGTAAAGAAATGTGAATTAGTAGCTATTTATTTCCTT AGTAGCAGGTAGGACTACTTAGCTTGTTACAACAGCTTTGATACACAGTAAGAAAACTCTACTGACAGATTACAAGCAGCCAAATGTGTT TACATTTCAGAGAAGGGTAAGGGAAGCCTCTCGTTGTCTTCATACTTTGGAATGTCTTAAGCTAAAATGTGACACTAGAGTTCAATTTCT TTTTTATTTTAAATGTCACTAAATTGTAGGTAAACTGTACCAAAAAGTTCTAGTTTAATTTTAACAGTAAAAACTCAGCATACCATGTTA CCACGTAAACAATAATGGCTGGTATTTTCTGTGGGTTAATTTAACATGACATAAACATAGGAAAGCCCTTGGCAAAATTCTACATCATTG AAGTAGACCATTTCTAAATGCAATTAAATAGTGAGGTTATTATAAAAATTAGAATTTAAAATATGACTTGTTGATAGTGCAGATTATAAT GTTACTTAGAAAGTTAAGAATTCGAGAGTAATGATGCTATTGGAGAACTGGTTTGCTATACGGCAGCAAAAACATAATGAGAATGTACCA TGAAGAAATTGTGTTAAATATTCACTTTGAGTGAAACTTTAAATATGTTTCCTCTTTTGAGCTACTGTTATTTAGCAGTTACCTAAAAAA GAATACATTTTTACTAGTCTACCATTAAAAATATAAAAGGCTTAACAAAAACGCATATAAAAGTTAATAAAATGTTACTCAGATTAGTAC TTTAATTGTTAAAATGTAATTAATGAGCTCCATAGAGCCCATACATCACAGTTCCATTGAAAATATCATCTGGACTAGAATCTCTTAAAC CCAGGAAGTGGAGGTTGCAGTGAGCCAAGATGGTGCCACTGCACTCCAGCCTGGGTGACAGGGCAAGACCCTGTCTCAAAAAAAAAAAAA AGAAAAGAAAAAGAAAGAAAATATTATGTGGAAATTTTTCATCTTTTTATGATGCCTGGGATAGATTTATGCAGTAGATTTATATATAAT GTTTAGTTTACAAACTTGTGAAACTATTTCATGTGGGTTCTGAAAGGCAAAACAGAAATGGCCAGTGCTGGTGATGTTTGATTAGACCAG CTCTTCTCAGCTGGGGTGATTCATTATCCCTCTCTGGTGACATTTGGCAATGTCTGGAGACCAGAGACATTTTTTATTTTCATGACTCAA GGGTGCTAATAGCATGTACTTAGTAGAGGTTAGGGATCCTGCTAAAGATCTTACAATGCACAAGTCAGCCTCTCACAGCAAAATAATTAT CCAGGCTGAGATGTCAGTAGTATCAAGGTTGACATCTCAGACCTGGATTAGACCTGGATTAGACCAAAATGAAATTTTGATTGTTCCACC TTGTCTTCACTTAAAGATAGATATACATGCTCACAGCATTCAAAATATGACTACAATTTAATGAAAATATTTTCTTATGGTAGATTACAA CTCACTAGATACACCATACATATGCCTTTTGGACATAATTGGTTAGATAGGAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT GTGTGTGTAGCATGAAGTTAGGCATCTCTATCCTTAACTGTGCTATGTGTTCCTAAGTAAGGACCTCGCTAGAATCATCCTGTAGAGTGC TCTGGAATACTCTATTATTAAGATCTTCAATTCTAAGCTCCCATTATCTTTCTTTGTTTATCTGAAATTAAGACCTTCAGAATTAGGCCT GGTACTTTTCCAGATTTGATCAGTTACATTTTGATATAACTGACTCTTAAAATTCAGCTTAGAAGACATTCAATAAGAAAATCTTTAATC ACTTTTGGTGATGCACCTGCCAAGAGGGGGCATCACTTTGTACCATCAGACTAATTAAAAAAATTGTTGTGTAGTCATAAAAATTAGGCT GATCCATAGGGGCAAAAGGAAGGGTGAAGAGACTAAAAACTAGTACCCTGATAGAATTTTAGTTTTTATTAGCCTCGATTTGAGAACTGC ATTGATTCCAAAGATCATGAAGGTAGGTGAAGGATTAAGTCATTCCATAATTAAGAAAAGTAATGTTTATATGAAAGATTTTTATATGGA CAATGACTCACAGACACATATGCTTTGTATAGAGGATTTTGCCAAAAGTTTATACAAAATTGCACATCTAAACTGCATAATTCTCATACA AGAAGTTAAGGAAGTGCTCACTGGATTTTGCTTCTGTATAGTTCACTTTTATCTGTCTTCACAAGGGTAGGAAGTAAATGATCTCAAATG GCACATGTTCAGACAATACTGTGTTTGGCTTTGTGATGTCTCATGTCTTTCTCTTGGCTAAAAAAAATTGTTTAGGCTATATATAACTTG TACCTGAAGCAATCTGGACAACATGGCTTAAAATGGAAAATAACTGAAAAAATCCTGGGATTTTAAATTTGCCAAAAATACCCTTGGATT AGTCAAAGGCTTTACAAGAGTGTTATAGATGATCCAAAATGGAAACAATATTGATAACATTTCTTTTCGTCAGCAGCTACATATTCCAGT TTTATAACTTTATTATATACATTTTTTGATTATTAATAGAAAGTCAGCCATCCAGAGTTTTAACTTCTGTGGTTGAAATATTGACTTTGT GAAATTTTTCACTGACAAATACTTGTTAGGAGGGACCTAAGGGGGAGGGGAATGTTACCAGTCCACTGAAAACTTTAGGAAATGTTCATT GTGTTGTGTAAATACTTTCCCACCAGCACCAGGTAATATATTCTCTATGTTTGTAGAATTCCAAAGATCAAAAGCTGTAAGGACGTTTAT GTGAACTTGACGCAAACTTGTGGAGGAATAAGGACTGAGAGTAATGTTGTGCTTTTTCTTTATCTTCCCGTCGTATAGGTCGACTCTCAG GTTATATGACTTTTATTGGGCACACGTCAGGGGTGGAAGTGGTAGAAGTGGGTTAACAATTTCAAGGCCTGGCAACCTAGGTCAAAACCT CTAATAAAGTCAGCAGTAAACATAACTAGCAACTTCATTCCACTATGTGCTAGGAGGAGGGTGAGGCAAGTTGAAAGGAGATGACCCTAT CCCCACACTCTCAGGATGTAAAAGGGCAGAGTGCTCTCTACCCTTAACCTTGGCTTTTTAGCACCGTCAGTCTCTGTCCTCTCCCAGGAG AGCTGCCTTGGCTCCAGAGTTGAGCTAGTAGCATTGTGACTAGAGAGGTAGTGTGGAAATTCGCTGAGGACCTCAAAATTTTACACTGCC TTAAACTGTTTTGTTTTTGCTTAAACTCGTGCTGTCTAAATGTGGGTGTTTTGTGGCAGAGTCTGATCACCCCGACCTAGTTATAGCCCT GCCAGTGATTCTAAAGTGGAACTTTTCCCCCTCATTCATATGGATAGTCTGAGTCCTTGAAGCTAGGGAGATATCAAATATTCTACCAGT TCCTACATAGCTTCTTTAAAAGTCCTAGAGACTAACTCACAGGAAGTCTGAAGCCCAGAGCGTCTGTTTATAAACTCCTAAATATGAGGC CACAATATTTAGGTTGAGCACTAGAAAATTTCTATTTTGCAAGTGGAAGGAGACTTGAATCTATAATTGCTGTAGCTTTTTTTCCCTTCT ATCATAAGAAAATGGATACCATCTGCTTTACCCTCAGCCCAGACTTGTCTTTTGAATTTTTTACATACATCTTAGGGGTGAGAGATTGAA ACAAGTGCATGAATGAAAAGCTTATTGAAACATAACACAGCCCCTGCTCACCATTTCAGTAAGGGAAAATACATGTTTCTGTTTCCCTCT AATTTGTTTTCTCTGGTGCCAACATTTCTGATTTCTTCTGTCTCTAATACATAAGGAATAAATACCATATTTTAAATTGACTTACATGCC TGCGAGCATTTGCCAGATAATCAAAGCCTATGACTCTAACTTTTTAAAGCACAGAAGAGGAATTATATTTTATGGTCACTCCTCTGTGTT TCTATTGATCTCTATATTGTGCTAAAATTCTTTCAGGTAATTTTTTTCTTGTTGAAGCTGTGGGATATAATCAATGATGCCAAGCTGTCT GAGAATTTTATAGAATAATATCCAAATATATTGATCCTGCCTCTTTCTGCTTCTATGTAATTAAACTTTCTTTTGATGTTTATTTTTAAA ATGTATGCTTCACACAACACCAATAAACATCTAAGAGATGTGATATAATCCAAGGCAAAGAAAAGTAAGAATCAGTTAATGTCTATTTTA TCTGCACAGCATTACGAACAGAAAATTGTAATAAAAAAAGGTTTAACCAAACTGAAAAAAAGAGAGACAAAATCTTGGTTTTAATTTGAA AAGATGATTGGGAGTGATCTCAGAAGAGAGTTCAGCAGGAAGCAAGGAAGAGGCTGTTGACCTTGAGTGCAGCCTCAAGAATGGAACCTT TTTGAAATATTTTAAAGGAAATATCTTGTCATCCAGCTGTTATGGTTAATAATGAATAGTTTTCTCTGGGTGAAGCTTATCCATTGCACA CCTGATGTGCTGGCCCCTGCGATTTCCCCAAATGTTGGAATGTTGCCTGCATAATTTGTGGTAATGGGGGACTGTGTTCCTGCTTTTACC TGGTTACAAAAAACAAAACAAAACAAAACAAAACAACAAACAGAAAAAAAAAGAGAGAAAAGATGCTAGAGGAAGCAGTGTGACAGACAG ATCATGAGATGCTGACGGAGAGAACAGAGTGGTACCTGTTTACCCACTTGGACCATGACAGTATCAAGGCTCCACCCCTTGCTGTCCCTT CCCAAGAGGTGCTCTCCTGGGAGTTTGATCACAGTGAAACAACACTCCCGTTTTCTTTTTCCTTTCTTTCTTTCTTTCTTTTTTTTTTTT TTTTTTTTTTTTGTTGAGACAGAGTTTTTTGCTCTTGTTGCCCAGGCTGGAGTGCAATGGCGTGATCTCGGCTCACCGCAACCTCCGCCT CCCAGGTTCAAGCGATTCTCGTGCCTCAGCCTCTGGAGTAGCTGGGATTACAGGCATGCGCCACCACACCCGGCTAATTTTGTACTTTTA GTAGAGATGGGGTTTCTCCATATTGGTCAGGCTGGTCCCGAACTCCTGACCTCAGGTGATCTGCCCGCCTCAGCCTCCCAAAGTGCTGGG ATTACAGGCATAAGCCACCGAGCCCAGCCCCACACTCCTGTTTTCATAGCCCTTTTTTGTCTGTACTTTGGTACATATTCCCCAAATAAG ATTATTATTTACATCTGTCATGATGAGGCAGTGATAGCAGCAAGTGTCACTTTGACCCTCACCCTTGGAAAGTGGGCTATGCATAGCTAG AGTTAGAACAGGAGGTTCTAATCCTGCTTCCACAATTACTTCAGTAACAGGCTTTTGTATCCATGATTACTTAAGCTGACTTAGATGCAT TTTCTACCCTGTATTCTAGTGTACACAACACAAACACACATAAGCCCTTTACCTGTGGAGAAGAGGGAGATGGTTGATTCAGTGGGAGTG GGGAGTGGCAGAGGGTGCCTTAACTTTTTCTGGCTTGACCCCTACTTCCTTATGTGTTTCCTTCATATACCTCTGTCACTTTAGAGATGT AATCATGTCTGTTCCAAGTTGTATCGTTATTATCAAGAAGTCCTATAAATGTAGCAAATGTGACTATTTTATAGAAATGCACAATAGTTT ATAGGCCTTGGAGAAGTCTGATAATAGTATGTAAATATCCTTCATTGAAGTCATAGAACCTTCTAGTAGGAAGCTCCATAGGTGATAACT GCAAGAGGATTAATGTTTGTTTCTCCAGTAAACACCGGAAGCAAGGAATCAATCTGTCACTGTTTATCATTCAGTCTTGAGCACCGTTGG GTGTTGATAGGTTACTATAGACACTCCCCTTATAATTAATATACAGGACTCACAATTTAGGATGTCTGATGGCCACTAGGGTACATCATA GAGACACTAGAGAGAAGAGAACAAATATAGCTCCATCAAAAAGCCTGCTTAATCTTTAACAAGTCTGAAATATTACTAAAATTCCAGTTA CCGTGCAGCATAGTCAGTCTAAAAAGCACTGGGGAAAAAGGTGTCTTTTTGGTCTCTTTAATTCTATTATGGCACATTTTAATATTATTC CACATGTGTGCAAACTATTTCTCAAGAGCAAAGTTTGAGGCTGGAGTTAAGAAAATAGAAAAATTAAAACATTATTTTTTCTCATATAAT ATAATCTGACTACTAGTTCATGGATATAATAATTCTGGGAAAAATTTTAGATTAAACTATAAAATTGAAATCACCTTTGAAGAGTATATG GAATTGCTTCTTTCTATTAAAGCCAACCTACATTGGCAAAAAGTGTGGAGAAAATCAGTGTGCTCAATTCTTTTTGTAGAGTTTCATCTA AAATGTTGCAGGTAAAAAAGAAAACTTTAATTGGTACTTTCTACGGTGTGATTAGAAAAATTAGTATCTATCTCTGTTGGTTCTGCTGAC TTGCTTCTTTCCACCGAATCTAAATGCAATGTCATAGGAGGAGGTTTGCTGTAAAAACATGTCTTTTTCTTTGGTGTATTCATTGTAATT ATGGCTGGCAGTGAGAAGGTTCGGTAAGTCTCAATTTCTCTACCTCCTTTACTTGGAGAAAATTTGTAAATGTACCCTGTGAATAAAATG >13130_13130_2_CASC1-ST8SIA1_CASC1_chr12_25348009_ENST00000395987_ST8SIA1_chr12_22408323_ENST00000396037_length(amino acids)=230AA_BP=1 MATPFQLPLKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQLVTANPSIIRQRFQNLLWSRKTFVDNMKIYNHS YIYMPAFSMKTGTEPSLRVYYTLSDVGANQTVLFANPNFLRSIGKFWKSRGIHAKRLSTGLFLVSAALGLCEEVAIYGFWPFSVNMHEQP -------------------------------------------------------------- >13130_13130_3_CASC1-ST8SIA1_CASC1_chr12_25348009_ENST00000545133_ST8SIA1_chr12_22408323_ENST00000396037_length(transcript)=8902nt_BP=51nt AATTTCTGCTCCGACTCTGCGGACTACTGCAGTGGAGCTTGACTCTTAATGGCAACCCCATTCCAGCTGCCATTGAAGAAATGCGCGGTG GTGGGAAATGGTGGGATTCTGAAGAAGAGTGGCTGTGGCCGTCAAATAGATGAAGCAAATTTTGTCATGCGATGCAATCTCCCTCCTTTG TCAAGTGAATACACTAAGGATGTTGGATCCAAAAGTCAGTTAGTGACAGCTAATCCCAGCATAATTCGGCAAAGGTTTCAGAACCTTCTG TGGTCCAGAAAGACATTTGTGGACAACATGAAAATTTATAACCACAGTTACATCTACATGCCTGCCTTTTCTATGAAGACAGGAACAGAG CCATCTTTGAGGGTTTATTATACACTGTCAGATGTTGGTGCCAATCAAACAGTGCTGTTTGCCAACCCCAACTTTCTGCGTAGCATTGGA AAGTTCTGGAAAAGTAGAGGAATCCATGCCAAGCGCCTGTCCACAGGACTTTTTCTGGTGAGCGCAGCTCTGGGTCTCTGTGAAGAGGTG GCCATCTATGGCTTCTGGCCCTTCTCTGTGAATATGCATGAGCAGCCCATCAGCCACCACTACTATGACAACGTCTTACCCTTTTCTGGC TTCCATGCCATGCCCGAGGAATTTCTCCAACTCTGGTATCTTCATAAAATCGGTGCACTGAGAATGCAGCTGGACCCATGTGAAGATACC TCACTCCAGCCCACTTCCTAGGAACAATGGAAGAAGAAAGGACTGAACCAGGGTATTTTTGTTAGGTTTTCTATGTGACTCCAAGAGGGA ATGGTCAAGTTGTTTCATGAGTTTGCATGGGCCCTTGGAAAAACAGGAAAGGAGCAATGAAGATCCAAGCAAAACTTTACTTTCAGCGTT GGCTTGGAGGACAAATAAGAAATGAAACATCCTATGAAATACTTTATAGCACATGGCAGATTTGCAACTAGTAAAATGCTGGTGAAATGC TGTTGGTAAAGCACATGGTTCAAATCTAGAAGATGCAGTTCAAAAACAAGACAGACTCGAGTTGTTAGGGCTGAGGAACCAATCAAGGTA GAACAAAGAAAATGTTGGGGTAAAAGTGTTGCTGATTGTCAACACAAACTGGCTTAATAATATTAATAAGAACCTGTCTTATTAAGACTG GCTTTAGAACCGTAGGTTTTTTTAAAAAATTATTATTTATTTTTGCCCTCTTTGGGGAAGTGGGTGGGTAGATTTAAAAAATCCCTTCCT GAGTAATAAAGATACAAAATGTTACTGCTGATAATTGTGATTTGTTGAGCCACGTCTATATTAACTATAGCTCCCCTCTATTTTTAAAAT TTTACATAAGAATTGCTTCTTCCTCTTTTGTCAAGTCCACAGAGACAATGTGAAGCATTATTGAATTTAGACTGTGTTGCTTCATAGTCT GGATAACAGGAGCCACTTTCCTTCCTCAGAATTTAGGACATAAACCCAATTTTAGGTCTGCATTATGTAAGCCTGTTTGCATTGTCATTT TTATTTTAGTGCAAAAGACTACCAATATGAGTGAATTATTTGTTTGTAAATTGGCATAATTGTCTTCATAATTTAATGTTCAGAAATGCA GTAAAGCACGTTGATGAAAAGCTTAGTCTCTGTGGAAGACAGACCAGAAGACAAATCCCTTTTCTATCTACTGTGGCATATTCACTGCAA GGTAAAGGACATGTATGCATACATGCAAGAATGAATTGAGCGAAACTTTGAATATGTTTCCTCTTTTGAGCTATTGTTATTTAGTAGTTA CCTAAAAAAGAATACATTTTTACTAGTATACCATTAAAAATGTAAAAGGCTTAACATGTATGCATACATGTAGACACACATACACACACA CAAAGTTAAACAAAGCTCATTACTGTGCAACTATGAAAGCTGAACTCATATGACCTGGTATGGCAAAAATTTGTAACCAGTGTTGGAGAA TCACAAATGTGTTATGCACTATCCATTACATGTTGATATAAGACAACCGAGCTCACTGGTTGCCGCACATAATACCCATAGCAGCACAAG ATGCAAGTCTTACCCCCAAATGCTTACCCGGAATGAGCAGAATTGTCTTACTCATCCTGATTTTACCCAAAATCTCATGAATGGGCTTGC TGTTGAGCGTGGTCACACAAGGTATAGTTTGTACAAGTAAAGAAATGTGAATTAGTAGCTATTTATTTCCTTAGTAGCAGGTAGGACTAC TTAGCTTGTTACAACAGCTTTGATACACAGTAAGAAAACTCTACTGACAGATTACAAGCAGCCAAATGTGTTTACATTTCAGAGAAGGGT AAGGGAAGCCTCTCGTTGTCTTCATACTTTGGAATGTCTTAAGCTAAAATGTGACACTAGAGTTCAATTTCTTTTTTATTTTAAATGTCA CTAAATTGTAGGTAAACTGTACCAAAAAGTTCTAGTTTAATTTTAACAGTAAAAACTCAGCATACCATGTTACCACGTAAACAATAATGG CTGGTATTTTCTGTGGGTTAATTTAACATGACATAAACATAGGAAAGCCCTTGGCAAAATTCTACATCATTGAAGTAGACCATTTCTAAA TGCAATTAAATAGTGAGGTTATTATAAAAATTAGAATTTAAAATATGACTTGTTGATAGTGCAGATTATAATGTTACTTAGAAAGTTAAG AATTCGAGAGTAATGATGCTATTGGAGAACTGGTTTGCTATACGGCAGCAAAAACATAATGAGAATGTACCATGAAGAAATTGTGTTAAA TATTCACTTTGAGTGAAACTTTAAATATGTTTCCTCTTTTGAGCTACTGTTATTTAGCAGTTACCTAAAAAAGAATACATTTTTACTAGT CTACCATTAAAAATATAAAAGGCTTAACAAAAACGCATATAAAAGTTAATAAAATGTTACTCAGATTAGTACTTTAATTGTTAAAATGTA ATTAATGAGCTCCATAGAGCCCATACATCACAGTTCCATTGAAAATATCATCTGGACTAGAATCTCTTAAACCCAGGAAGTGGAGGTTGC AGTGAGCCAAGATGGTGCCACTGCACTCCAGCCTGGGTGACAGGGCAAGACCCTGTCTCAAAAAAAAAAAAAAGAAAAGAAAAAGAAAGA AAATATTATGTGGAAATTTTTCATCTTTTTATGATGCCTGGGATAGATTTATGCAGTAGATTTATATATAATGTTTAGTTTACAAACTTG TGAAACTATTTCATGTGGGTTCTGAAAGGCAAAACAGAAATGGCCAGTGCTGGTGATGTTTGATTAGACCAGCTCTTCTCAGCTGGGGTG ATTCATTATCCCTCTCTGGTGACATTTGGCAATGTCTGGAGACCAGAGACATTTTTTATTTTCATGACTCAAGGGTGCTAATAGCATGTA CTTAGTAGAGGTTAGGGATCCTGCTAAAGATCTTACAATGCACAAGTCAGCCTCTCACAGCAAAATAATTATCCAGGCTGAGATGTCAGT AGTATCAAGGTTGACATCTCAGACCTGGATTAGACCTGGATTAGACCAAAATGAAATTTTGATTGTTCCACCTTGTCTTCACTTAAAGAT AGATATACATGCTCACAGCATTCAAAATATGACTACAATTTAATGAAAATATTTTCTTATGGTAGATTACAACTCACTAGATACACCATA CATATGCCTTTTGGACATAATTGGTTAGATAGGAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTAGCATGAAGT TAGGCATCTCTATCCTTAACTGTGCTATGTGTTCCTAAGTAAGGACCTCGCTAGAATCATCCTGTAGAGTGCTCTGGAATACTCTATTAT TAAGATCTTCAATTCTAAGCTCCCATTATCTTTCTTTGTTTATCTGAAATTAAGACCTTCAGAATTAGGCCTGGTACTTTTCCAGATTTG ATCAGTTACATTTTGATATAACTGACTCTTAAAATTCAGCTTAGAAGACATTCAATAAGAAAATCTTTAATCACTTTTGGTGATGCACCT GCCAAGAGGGGGCATCACTTTGTACCATCAGACTAATTAAAAAAATTGTTGTGTAGTCATAAAAATTAGGCTGATCCATAGGGGCAAAAG GAAGGGTGAAGAGACTAAAAACTAGTACCCTGATAGAATTTTAGTTTTTATTAGCCTCGATTTGAGAACTGCATTGATTCCAAAGATCAT GAAGGTAGGTGAAGGATTAAGTCATTCCATAATTAAGAAAAGTAATGTTTATATGAAAGATTTTTATATGGACAATGACTCACAGACACA TATGCTTTGTATAGAGGATTTTGCCAAAAGTTTATACAAAATTGCACATCTAAACTGCATAATTCTCATACAAGAAGTTAAGGAAGTGCT CACTGGATTTTGCTTCTGTATAGTTCACTTTTATCTGTCTTCACAAGGGTAGGAAGTAAATGATCTCAAATGGCACATGTTCAGACAATA CTGTGTTTGGCTTTGTGATGTCTCATGTCTTTCTCTTGGCTAAAAAAAATTGTTTAGGCTATATATAACTTGTACCTGAAGCAATCTGGA CAACATGGCTTAAAATGGAAAATAACTGAAAAAATCCTGGGATTTTAAATTTGCCAAAAATACCCTTGGATTAGTCAAAGGCTTTACAAG AGTGTTATAGATGATCCAAAATGGAAACAATATTGATAACATTTCTTTTCGTCAGCAGCTACATATTCCAGTTTTATAACTTTATTATAT ACATTTTTTGATTATTAATAGAAAGTCAGCCATCCAGAGTTTTAACTTCTGTGGTTGAAATATTGACTTTGTGAAATTTTTCACTGACAA ATACTTGTTAGGAGGGACCTAAGGGGGAGGGGAATGTTACCAGTCCACTGAAAACTTTAGGAAATGTTCATTGTGTTGTGTAAATACTTT CCCACCAGCACCAGGTAATATATTCTCTATGTTTGTAGAATTCCAAAGATCAAAAGCTGTAAGGACGTTTATGTGAACTTGACGCAAACT TGTGGAGGAATAAGGACTGAGAGTAATGTTGTGCTTTTTCTTTATCTTCCCGTCGTATAGGTCGACTCTCAGGTTATATGACTTTTATTG GGCACACGTCAGGGGTGGAAGTGGTAGAAGTGGGTTAACAATTTCAAGGCCTGGCAACCTAGGTCAAAACCTCTAATAAAGTCAGCAGTA AACATAACTAGCAACTTCATTCCACTATGTGCTAGGAGGAGGGTGAGGCAAGTTGAAAGGAGATGACCCTATCCCCACACTCTCAGGATG TAAAAGGGCAGAGTGCTCTCTACCCTTAACCTTGGCTTTTTAGCACCGTCAGTCTCTGTCCTCTCCCAGGAGAGCTGCCTTGGCTCCAGA GTTGAGCTAGTAGCATTGTGACTAGAGAGGTAGTGTGGAAATTCGCTGAGGACCTCAAAATTTTACACTGCCTTAAACTGTTTTGTTTTT GCTTAAACTCGTGCTGTCTAAATGTGGGTGTTTTGTGGCAGAGTCTGATCACCCCGACCTAGTTATAGCCCTGCCAGTGATTCTAAAGTG GAACTTTTCCCCCTCATTCATATGGATAGTCTGAGTCCTTGAAGCTAGGGAGATATCAAATATTCTACCAGTTCCTACATAGCTTCTTTA AAAGTCCTAGAGACTAACTCACAGGAAGTCTGAAGCCCAGAGCGTCTGTTTATAAACTCCTAAATATGAGGCCACAATATTTAGGTTGAG CACTAGAAAATTTCTATTTTGCAAGTGGAAGGAGACTTGAATCTATAATTGCTGTAGCTTTTTTTCCCTTCTATCATAAGAAAATGGATA CCATCTGCTTTACCCTCAGCCCAGACTTGTCTTTTGAATTTTTTACATACATCTTAGGGGTGAGAGATTGAAACAAGTGCATGAATGAAA AGCTTATTGAAACATAACACAGCCCCTGCTCACCATTTCAGTAAGGGAAAATACATGTTTCTGTTTCCCTCTAATTTGTTTTCTCTGGTG CCAACATTTCTGATTTCTTCTGTCTCTAATACATAAGGAATAAATACCATATTTTAAATTGACTTACATGCCTGCGAGCATTTGCCAGAT AATCAAAGCCTATGACTCTAACTTTTTAAAGCACAGAAGAGGAATTATATTTTATGGTCACTCCTCTGTGTTTCTATTGATCTCTATATT GTGCTAAAATTCTTTCAGGTAATTTTTTTCTTGTTGAAGCTGTGGGATATAATCAATGATGCCAAGCTGTCTGAGAATTTTATAGAATAA TATCCAAATATATTGATCCTGCCTCTTTCTGCTTCTATGTAATTAAACTTTCTTTTGATGTTTATTTTTAAAATGTATGCTTCACACAAC ACCAATAAACATCTAAGAGATGTGATATAATCCAAGGCAAAGAAAAGTAAGAATCAGTTAATGTCTATTTTATCTGCACAGCATTACGAA CAGAAAATTGTAATAAAAAAAGGTTTAACCAAACTGAAAAAAAGAGAGACAAAATCTTGGTTTTAATTTGAAAAGATGATTGGGAGTGAT CTCAGAAGAGAGTTCAGCAGGAAGCAAGGAAGAGGCTGTTGACCTTGAGTGCAGCCTCAAGAATGGAACCTTTTTGAAATATTTTAAAGG AAATATCTTGTCATCCAGCTGTTATGGTTAATAATGAATAGTTTTCTCTGGGTGAAGCTTATCCATTGCACACCTGATGTGCTGGCCCCT GCGATTTCCCCAAATGTTGGAATGTTGCCTGCATAATTTGTGGTAATGGGGGACTGTGTTCCTGCTTTTACCTGGTTACAAAAAACAAAA CAAAACAAAACAAAACAACAAACAGAAAAAAAAAGAGAGAAAAGATGCTAGAGGAAGCAGTGTGACAGACAGATCATGAGATGCTGACGG AGAGAACAGAGTGGTACCTGTTTACCCACTTGGACCATGACAGTATCAAGGCTCCACCCCTTGCTGTCCCTTCCCAAGAGGTGCTCTCCT GGGAGTTTGATCACAGTGAAACAACACTCCCGTTTTCTTTTTCCTTTCTTTCTTTCTTTCTTTTTTTTTTTTTTTTTTTTTTTTGTTGAG ACAGAGTTTTTTGCTCTTGTTGCCCAGGCTGGAGTGCAATGGCGTGATCTCGGCTCACCGCAACCTCCGCCTCCCAGGTTCAAGCGATTC TCGTGCCTCAGCCTCTGGAGTAGCTGGGATTACAGGCATGCGCCACCACACCCGGCTAATTTTGTACTTTTAGTAGAGATGGGGTTTCTC CATATTGGTCAGGCTGGTCCCGAACTCCTGACCTCAGGTGATCTGCCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATAAGCCAC CGAGCCCAGCCCCACACTCCTGTTTTCATAGCCCTTTTTTGTCTGTACTTTGGTACATATTCCCCAAATAAGATTATTATTTACATCTGT CATGATGAGGCAGTGATAGCAGCAAGTGTCACTTTGACCCTCACCCTTGGAAAGTGGGCTATGCATAGCTAGAGTTAGAACAGGAGGTTC TAATCCTGCTTCCACAATTACTTCAGTAACAGGCTTTTGTATCCATGATTACTTAAGCTGACTTAGATGCATTTTCTACCCTGTATTCTA GTGTACACAACACAAACACACATAAGCCCTTTACCTGTGGAGAAGAGGGAGATGGTTGATTCAGTGGGAGTGGGGAGTGGCAGAGGGTGC CTTAACTTTTTCTGGCTTGACCCCTACTTCCTTATGTGTTTCCTTCATATACCTCTGTCACTTTAGAGATGTAATCATGTCTGTTCCAAG TTGTATCGTTATTATCAAGAAGTCCTATAAATGTAGCAAATGTGACTATTTTATAGAAATGCACAATAGTTTATAGGCCTTGGAGAAGTC TGATAATAGTATGTAAATATCCTTCATTGAAGTCATAGAACCTTCTAGTAGGAAGCTCCATAGGTGATAACTGCAAGAGGATTAATGTTT GTTTCTCCAGTAAACACCGGAAGCAAGGAATCAATCTGTCACTGTTTATCATTCAGTCTTGAGCACCGTTGGGTGTTGATAGGTTACTAT AGACACTCCCCTTATAATTAATATACAGGACTCACAATTTAGGATGTCTGATGGCCACTAGGGTACATCATAGAGACACTAGAGAGAAGA GAACAAATATAGCTCCATCAAAAAGCCTGCTTAATCTTTAACAAGTCTGAAATATTACTAAAATTCCAGTTACCGTGCAGCATAGTCAGT CTAAAAAGCACTGGGGAAAAAGGTGTCTTTTTGGTCTCTTTAATTCTATTATGGCACATTTTAATATTATTCCACATGTGTGCAAACTAT TTCTCAAGAGCAAAGTTTGAGGCTGGAGTTAAGAAAATAGAAAAATTAAAACATTATTTTTTCTCATATAATATAATCTGACTACTAGTT CATGGATATAATAATTCTGGGAAAAATTTTAGATTAAACTATAAAATTGAAATCACCTTTGAAGAGTATATGGAATTGCTTCTTTCTATT AAAGCCAACCTACATTGGCAAAAAGTGTGGAGAAAATCAGTGTGCTCAATTCTTTTTGTAGAGTTTCATCTAAAATGTTGCAGGTAAAAA AGAAAACTTTAATTGGTACTTTCTACGGTGTGATTAGAAAAATTAGTATCTATCTCTGTTGGTTCTGCTGACTTGCTTCTTTCCACCGAA TCTAAATGCAATGTCATAGGAGGAGGTTTGCTGTAAAAACATGTCTTTTTCTTTGGTGTATTCATTGTAATTATGGCTGGCAGTGAGAAG >13130_13130_3_CASC1-ST8SIA1_CASC1_chr12_25348009_ENST00000545133_ST8SIA1_chr12_22408323_ENST00000396037_length(amino acids)=230AA_BP=1 MATPFQLPLKKCAVVGNGGILKKSGCGRQIDEANFVMRCNLPPLSSEYTKDVGSKSQLVTANPSIIRQRFQNLLWSRKTFVDNMKIYNHS YIYMPAFSMKTGTEPSLRVYYTLSDVGANQTVLFANPNFLRSIGKFWKSRGIHAKRLSTGLFLVSAALGLCEEVAIYGFWPFSVNMHEQP -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for CASC1-ST8SIA1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for CASC1-ST8SIA1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for CASC1-ST8SIA1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | CASC1 | C0024121 | Lung Neoplasms | 1 | CTD_human |
| Hgene | CASC1 | C0242379 | Malignant neoplasm of lung | 1 | CTD_human |
| Tgene | C0023895 | Liver diseases | 1 | CTD_human | |
| Tgene | C0086565 | Liver Dysfunction | 1 | CTD_human | |
| Tgene | C0149504 | Encephalopathy, Toxic | 1 | CTD_human | |
| Tgene | C0154659 | Toxic Encephalitis | 1 | CTD_human | |
| Tgene | C0235032 | Neurotoxicity Syndromes | 1 | CTD_human |
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