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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Fusion gene:NCBP3-ATP2A3 (FusionGDB2 ID:HG55421TG489)

Fusion Gene Summary for NCBP3-ATP2A3

check button Fusion gene summary
Fusion gene informationFusion gene name: NCBP3-ATP2A3
Fusion gene ID: hg55421tg489
HgeneTgene
Gene symbol

NCBP3

ATP2A3

Gene ID

55421

489

Gene namenuclear cap binding subunit 3ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
SynonymsC17orf85|ELG|HSA277841SERCA3
Cytomap('C17orf85','NCBP3')('ATP2A3','ATP2A3')

17p13.2

17p13.2

Type of geneprotein-codingprotein-coding
Descriptionnuclear cap-binding protein subunit 3CTD-3195I5.1CTD-3195I5.5sarcoplasmic/endoplasmic reticulum calcium ATPase 3ATPase, Ca(2+)-transporting, ubiquitousATPase, Ca++ transporting, ubiquitousSR Ca(2+)-ATPase 3adenosine triphosphatase, calciumcalcium pump 3calcium-translocating P-type ATPasesarco/endoplasmic ret
Modification date2020031320200313
UniProtAcc.

Q93084

Ensembl transtripts involved in fusion geneENST00000158149, ENST00000389005, 
ENST00000577169, 
Fusion gene scores* DoF score2 X 2 X 2=85 X 3 X 5=75
# samples 25
** MAII scorelog2(2/8*10)=1.32192809488736log2(5/75*10)=-0.584962500721156
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: NCBP3 [Title/Abstract] AND ATP2A3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointC17orf85(3717616)-ATP2A3(3857004), # samples:2
NCBP3(3717616)-ATP2A3(3857004), # samples:1
Anticipated loss of major functional domain due to fusion event.C17orf85-ATP2A3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
C17orf85-ATP2A3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
C17orf85-ATP2A3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
C17orf85-ATP2A3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
C17orf85-ATP2A3 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneATP2A3

GO:0006919

activation of cysteine-type endopeptidase activity involved in apoptotic process

16725111

TgeneATP2A3

GO:0070059

intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

16725111

TgeneATP2A3

GO:0070588

calcium ion transmembrane transport

9843705|11956212

TgeneATP2A3

GO:1903515

calcium ion transport from cytosol to endoplasmic reticulum

15028735


check buttonFusion gene breakpoints across C17orf85 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across ATP2A3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SKCMTCGA-D9-A6E9-06AC17orf85chr17

3717616

-ATP2A3chr17

3857004

-
ChimerDB4SKCMTCGA-D9-A6E9-06ANCBP3chr17

3717616

-ATP2A3chr17

3857004

-


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Fusion Gene ORF analysis for NCBP3-ATP2A3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000158149ENST00000352011C17orf85chr17

3717616

-ATP2A3chr17

3857004

-
5CDS-5UTRENST00000158149ENST00000359983C17orf85chr17

3717616

-ATP2A3chr17

3857004

-
5CDS-5UTRENST00000158149ENST00000397039C17orf85chr17

3717616

-ATP2A3chr17

3857004

-
5CDS-5UTRENST00000158149ENST00000397043C17orf85chr17

3717616

-ATP2A3chr17

3857004

-
5CDS-5UTRENST00000389005ENST00000352011C17orf85chr17

3717616

-ATP2A3chr17

3857004

-
5CDS-5UTRENST00000389005ENST00000359983C17orf85chr17

3717616

-ATP2A3chr17

3857004

-
5CDS-5UTRENST00000389005ENST00000397039C17orf85chr17

3717616

-ATP2A3chr17

3857004

-
5CDS-5UTRENST00000389005ENST00000397043C17orf85chr17

3717616

-ATP2A3chr17

3857004

-
Frame-shiftENST00000158149ENST00000309890C17orf85chr17

3717616

-ATP2A3chr17

3857004

-
Frame-shiftENST00000158149ENST00000397035C17orf85chr17

3717616

-ATP2A3chr17

3857004

-
Frame-shiftENST00000158149ENST00000397041C17orf85chr17

3717616

-ATP2A3chr17

3857004

-
Frame-shiftENST00000389005ENST00000397035C17orf85chr17

3717616

-ATP2A3chr17

3857004

-
In-frameENST00000389005ENST00000309890C17orf85chr17

3717616

-ATP2A3chr17

3857004

-
In-frameENST00000389005ENST00000397041C17orf85chr17

3717616

-ATP2A3chr17

3857004

-
intron-3CDSENST00000577169ENST00000309890C17orf85chr17

3717616

-ATP2A3chr17

3857004

-
intron-3CDSENST00000577169ENST00000397035C17orf85chr17

3717616

-ATP2A3chr17

3857004

-
intron-3CDSENST00000577169ENST00000397041C17orf85chr17

3717616

-ATP2A3chr17

3857004

-
intron-5UTRENST00000577169ENST00000352011C17orf85chr17

3717616

-ATP2A3chr17

3857004

-
intron-5UTRENST00000577169ENST00000359983C17orf85chr17

3717616

-ATP2A3chr17

3857004

-
intron-5UTRENST00000577169ENST00000397039C17orf85chr17

3717616

-ATP2A3chr17

3857004

-
intron-5UTRENST00000577169ENST00000397043C17orf85chr17

3717616

-ATP2A3chr17

3857004

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000389005C17orf85chr173717616-ENST00000397041ATP2A3chr173857004-608416552845361502
ENST00000389005C17orf85chr173717616-ENST00000309890ATP2A3chr173857004-618516552846261532

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000389005ENST00000397041C17orf85chr173717616-ATP2A3chr173857004-0.0032211650.9967789
ENST00000389005ENST00000309890C17orf85chr173717616-ATP2A3chr173857004-0.0020322970.99796766

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Fusion Genomic Features for NCBP3-ATP2A3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for NCBP3-ATP2A3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/:3717616/:3857004)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ATP2A3

Q93084

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports calcium ions from the cytosol into the sarcoplasmic/endoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction. {ECO:0000269|PubMed:11956212, ECO:0000269|PubMed:15028735}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneC17orf85chr17:3717616chr17:3857004ENST00000389005-1213340_376542621.0Compositional biasNote=Glu-rich
HgeneC17orf85chr17:3717616chr17:3857004ENST00000158149-1314126_187262341.0RegionRNA recognition motif (RRM) domain
HgeneC17orf85chr17:3717616chr17:3857004ENST00000389005-1213126_187542621.0RegionRNA recognition motif (RRM) domain
TgeneATP2A3chr17:3717616chr17:3857004ENST00000309890022111_253391030.0Topological domainCytoplasmic
TgeneATP2A3chr17:3717616chr17:3857004ENST00000309890022274_295391030.0Topological domainLumenal
TgeneATP2A3chr17:3717616chr17:3857004ENST00000309890022314_757391030.0Topological domainCytoplasmic
TgeneATP2A3chr17:3717616chr17:3857004ENST0000030989002270_89391030.0Topological domainLumenal
TgeneATP2A3chr17:3717616chr17:3857004ENST00000309890022778_787391030.0Topological domainLumenal
TgeneATP2A3chr17:3717616chr17:3857004ENST00000309890022809_828391030.0Topological domainCytoplasmic
TgeneATP2A3chr17:3717616chr17:3857004ENST00000309890022852_897391030.0Topological domainLumenal
TgeneATP2A3chr17:3717616chr17:3857004ENST00000309890022918_930391030.0Topological domainCytoplasmic
TgeneATP2A3chr17:3717616chr17:3857004ENST00000309890022950_964391030.0Topological domainLumenal
TgeneATP2A3chr17:3717616chr17:3857004ENST00000309890022986_999391030.0Topological domainCytoplasmic
TgeneATP2A3chr17:3717616chr17:3857004ENST00000352011022111_253391044.0Topological domainCytoplasmic
TgeneATP2A3chr17:3717616chr17:3857004ENST00000352011022274_295391044.0Topological domainLumenal
TgeneATP2A3chr17:3717616chr17:3857004ENST00000352011022314_757391044.0Topological domainCytoplasmic
TgeneATP2A3chr17:3717616chr17:3857004ENST0000035201102270_89391044.0Topological domainLumenal
TgeneATP2A3chr17:3717616chr17:3857004ENST00000352011022778_787391044.0Topological domainLumenal
TgeneATP2A3chr17:3717616chr17:3857004ENST00000352011022809_828391044.0Topological domainCytoplasmic
TgeneATP2A3chr17:3717616chr17:3857004ENST00000352011022852_897391044.0Topological domainLumenal
TgeneATP2A3chr17:3717616chr17:3857004ENST00000352011022918_930391044.0Topological domainCytoplasmic
TgeneATP2A3chr17:3717616chr17:3857004ENST00000352011022950_964391044.0Topological domainLumenal
TgeneATP2A3chr17:3717616chr17:3857004ENST00000352011022986_999391044.0Topological domainCytoplasmic
TgeneATP2A3chr17:3717616chr17:3857004ENST00000359983023111_253391053.0Topological domainCytoplasmic
TgeneATP2A3chr17:3717616chr17:3857004ENST00000359983023274_295391053.0Topological domainLumenal
TgeneATP2A3chr17:3717616chr17:3857004ENST00000359983023314_757391053.0Topological domainCytoplasmic
TgeneATP2A3chr17:3717616chr17:3857004ENST0000035998302370_89391053.0Topological domainLumenal
TgeneATP2A3chr17:3717616chr17:3857004ENST00000359983023778_787391053.0Topological domainLumenal
TgeneATP2A3chr17:3717616chr17:3857004ENST00000359983023809_828391053.0Topological domainCytoplasmic
TgeneATP2A3chr17:3717616chr17:3857004ENST00000359983023852_897391053.0Topological domainLumenal
TgeneATP2A3chr17:3717616chr17:3857004ENST00000359983023918_930391053.0Topological domainCytoplasmic
TgeneATP2A3chr17:3717616chr17:3857004ENST00000359983023950_964391053.0Topological domainLumenal
TgeneATP2A3chr17:3717616chr17:3857004ENST00000359983023986_999391053.0Topological domainCytoplasmic
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397035023111_253391266.3333333333333Topological domainCytoplasmic
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397035023274_295391266.3333333333333Topological domainLumenal
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397035023314_757391266.3333333333333Topological domainCytoplasmic
TgeneATP2A3chr17:3717616chr17:3857004ENST0000039703502370_89391266.3333333333333Topological domainLumenal
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397035023778_787391266.3333333333333Topological domainLumenal
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397035023809_828391266.3333333333333Topological domainCytoplasmic
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397035023852_897391266.3333333333333Topological domainLumenal
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397035023918_930391266.3333333333333Topological domainCytoplasmic
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397035023950_964391266.3333333333333Topological domainLumenal
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397035023986_999391266.3333333333333Topological domainCytoplasmic
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397041021111_253391000.0Topological domainCytoplasmic
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397041021274_295391000.0Topological domainLumenal
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397041021314_757391000.0Topological domainCytoplasmic
TgeneATP2A3chr17:3717616chr17:3857004ENST0000039704102170_89391000.0Topological domainLumenal
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397041021778_787391000.0Topological domainLumenal
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397041021809_828391000.0Topological domainCytoplasmic
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397041021852_897391000.0Topological domainLumenal
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397041021918_930391000.0Topological domainCytoplasmic
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397041021950_964391000.0Topological domainLumenal
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397041021986_999391000.0Topological domainCytoplasmic
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397043021111_25339999.0Topological domainCytoplasmic
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397043021274_29539999.0Topological domainLumenal
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397043021314_75739999.0Topological domainCytoplasmic
TgeneATP2A3chr17:3717616chr17:3857004ENST0000039704302170_8939999.0Topological domainLumenal
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397043021778_78739999.0Topological domainLumenal
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397043021809_82839999.0Topological domainCytoplasmic
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397043021852_89739999.0Topological domainLumenal
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397043021918_93039999.0Topological domainCytoplasmic
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397043021950_96439999.0Topological domainLumenal
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397043021986_99939999.0Topological domainCytoplasmic
TgeneATP2A3chr17:3717616chr17:3857004ENST00000309890022254_273391030.0TransmembraneHelical%3B Name%3D3
TgeneATP2A3chr17:3717616chr17:3857004ENST00000309890022296_313391030.0TransmembraneHelical%3B Name%3D4
TgeneATP2A3chr17:3717616chr17:3857004ENST0000030989002249_69391030.0TransmembraneHelical%3B Name%3D1
TgeneATP2A3chr17:3717616chr17:3857004ENST00000309890022758_777391030.0TransmembraneHelical%3B Name%3D5
TgeneATP2A3chr17:3717616chr17:3857004ENST00000309890022829_851391030.0TransmembraneHelical%3B Name%3D7
TgeneATP2A3chr17:3717616chr17:3857004ENST00000309890022898_917391030.0TransmembraneHelical%3B Name%3D8
TgeneATP2A3chr17:3717616chr17:3857004ENST0000030989002290_110391030.0TransmembraneHelical%3B Name%3D2
TgeneATP2A3chr17:3717616chr17:3857004ENST00000309890022931_949391030.0TransmembraneHelical%3B Name%3D9
TgeneATP2A3chr17:3717616chr17:3857004ENST00000309890022965_985391030.0TransmembraneHelical%3B Name%3D10
TgeneATP2A3chr17:3717616chr17:3857004ENST00000352011022254_273391044.0TransmembraneHelical%3B Name%3D3
TgeneATP2A3chr17:3717616chr17:3857004ENST00000352011022296_313391044.0TransmembraneHelical%3B Name%3D4
TgeneATP2A3chr17:3717616chr17:3857004ENST0000035201102249_69391044.0TransmembraneHelical%3B Name%3D1
TgeneATP2A3chr17:3717616chr17:3857004ENST00000352011022758_777391044.0TransmembraneHelical%3B Name%3D5
TgeneATP2A3chr17:3717616chr17:3857004ENST00000352011022829_851391044.0TransmembraneHelical%3B Name%3D7
TgeneATP2A3chr17:3717616chr17:3857004ENST00000352011022898_917391044.0TransmembraneHelical%3B Name%3D8
TgeneATP2A3chr17:3717616chr17:3857004ENST0000035201102290_110391044.0TransmembraneHelical%3B Name%3D2
TgeneATP2A3chr17:3717616chr17:3857004ENST00000352011022931_949391044.0TransmembraneHelical%3B Name%3D9
TgeneATP2A3chr17:3717616chr17:3857004ENST00000352011022965_985391044.0TransmembraneHelical%3B Name%3D10
TgeneATP2A3chr17:3717616chr17:3857004ENST00000359983023254_273391053.0TransmembraneHelical%3B Name%3D3
TgeneATP2A3chr17:3717616chr17:3857004ENST00000359983023296_313391053.0TransmembraneHelical%3B Name%3D4
TgeneATP2A3chr17:3717616chr17:3857004ENST0000035998302349_69391053.0TransmembraneHelical%3B Name%3D1
TgeneATP2A3chr17:3717616chr17:3857004ENST00000359983023758_777391053.0TransmembraneHelical%3B Name%3D5
TgeneATP2A3chr17:3717616chr17:3857004ENST00000359983023829_851391053.0TransmembraneHelical%3B Name%3D7
TgeneATP2A3chr17:3717616chr17:3857004ENST00000359983023898_917391053.0TransmembraneHelical%3B Name%3D8
TgeneATP2A3chr17:3717616chr17:3857004ENST0000035998302390_110391053.0TransmembraneHelical%3B Name%3D2
TgeneATP2A3chr17:3717616chr17:3857004ENST00000359983023931_949391053.0TransmembraneHelical%3B Name%3D9
TgeneATP2A3chr17:3717616chr17:3857004ENST00000359983023965_985391053.0TransmembraneHelical%3B Name%3D10
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397035023254_273391266.3333333333333TransmembraneHelical%3B Name%3D3
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397035023296_313391266.3333333333333TransmembraneHelical%3B Name%3D4
TgeneATP2A3chr17:3717616chr17:3857004ENST0000039703502349_69391266.3333333333333TransmembraneHelical%3B Name%3D1
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397035023758_777391266.3333333333333TransmembraneHelical%3B Name%3D5
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397035023829_851391266.3333333333333TransmembraneHelical%3B Name%3D7
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397035023898_917391266.3333333333333TransmembraneHelical%3B Name%3D8
TgeneATP2A3chr17:3717616chr17:3857004ENST0000039703502390_110391266.3333333333333TransmembraneHelical%3B Name%3D2
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397035023931_949391266.3333333333333TransmembraneHelical%3B Name%3D9
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397035023965_985391266.3333333333333TransmembraneHelical%3B Name%3D10
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397041021254_273391000.0TransmembraneHelical%3B Name%3D3
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397041021296_313391000.0TransmembraneHelical%3B Name%3D4
TgeneATP2A3chr17:3717616chr17:3857004ENST0000039704102149_69391000.0TransmembraneHelical%3B Name%3D1
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397041021758_777391000.0TransmembraneHelical%3B Name%3D5
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397041021829_851391000.0TransmembraneHelical%3B Name%3D7
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397041021898_917391000.0TransmembraneHelical%3B Name%3D8
TgeneATP2A3chr17:3717616chr17:3857004ENST0000039704102190_110391000.0TransmembraneHelical%3B Name%3D2
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397041021931_949391000.0TransmembraneHelical%3B Name%3D9
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397041021965_985391000.0TransmembraneHelical%3B Name%3D10
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397043021254_27339999.0TransmembraneHelical%3B Name%3D3
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397043021296_31339999.0TransmembraneHelical%3B Name%3D4
TgeneATP2A3chr17:3717616chr17:3857004ENST0000039704302149_6939999.0TransmembraneHelical%3B Name%3D1
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397043021758_77739999.0TransmembraneHelical%3B Name%3D5
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397043021829_85139999.0TransmembraneHelical%3B Name%3D7
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397043021898_91739999.0TransmembraneHelical%3B Name%3D8
TgeneATP2A3chr17:3717616chr17:3857004ENST0000039704302190_11039999.0TransmembraneHelical%3B Name%3D2
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397043021931_94939999.0TransmembraneHelical%3B Name%3D9
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397043021965_98539999.0TransmembraneHelical%3B Name%3D10

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneC17orf85chr17:3717616chr17:3857004ENST00000158149-1314340_376262341.0Compositional biasNote=Glu-rich
TgeneATP2A3chr17:3717616chr17:3857004ENST000003098900221_48391030.0Topological domainCytoplasmic
TgeneATP2A3chr17:3717616chr17:3857004ENST000003520110221_48391044.0Topological domainCytoplasmic
TgeneATP2A3chr17:3717616chr17:3857004ENST000003599830231_48391053.0Topological domainCytoplasmic
TgeneATP2A3chr17:3717616chr17:3857004ENST000003970350231_48391266.3333333333333Topological domainCytoplasmic
TgeneATP2A3chr17:3717616chr17:3857004ENST000003970410211_48391000.0Topological domainCytoplasmic
TgeneATP2A3chr17:3717616chr17:3857004ENST000003970430211_4839999.0Topological domainCytoplasmic


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Fusion Gene Sequence for NCBP3-ATP2A3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>11114_11114_1_C17orf85-ATP2A3_C17orf85_chr17_3717616_ENST00000389005_ATP2A3_chr17_3857004_ENST00000309890_length(transcript)=6185nt_BP=1655nt
CTCTCAGTGGTGCGGCCGGCAGGCAGCGATGGCGGCCGTACGGGGCCTGCGGGTGTCGGTGAAGGCGGAGGCCCCGGCGGGGCCGGCCCT
GGGGCTCCCGTCCCCTGAGGCGGAGTCCGGTGTTGACCGTGGCGAGCCGGAGCCCATGGAGGTGGAGGAGGGCGAGCTGGAAATCGTGCC
TGTGCGGCGCTCGCTCAAGGAACTGATCCCGGACACGAGCAGAAGATATGAAAACAAGGCTGGCAGCTTCATCACTGGAATTGATGTCAC
CTCCAAGGAAGCAATTGAAAAGAAAGAGCAGCGAGCCAAGCGCTTCCATTTTCGATCGGAAGTAAATCTTGCCCAAAGAAATGTAGCCTT
GGACCGAGACATGATGAAGAAAGCAATCCCCAAGGTGAGACTGGAGACAATCTATATTTGCGGAGTAGATGAGATGAGCACCCAAGATGT
CTTTTCCTATTTTAAAGAATATCCTCCAGCTCACATCGAATGGTTGGATGATACCTCCTGTAATGTAGTTTGGCTGGATGAAATGACAGC
CACACGAGCACTTATCAATATGAGCTCCCTGCCTGCACAGGATAAGATCAGAAGCAGGGATGCCAGTGAGGACAAGTCAGCTGAGAAAAG
GAAAAAAGACAAGCAGGAAGACAGTTCAGATGATGATGAAGCTGAAGAAGGAGAGGTTGAAGATGAGAACTCAAGTGATGTAGAGTTGGA
TACGTTGTCTCAGGTAGAAGAGGAGTCTTTGTTAAGAAACGATCTTCGTCCAGCTAACAAACTTGCTAAAGGAAATAGGTTATTCATGAG
ATTTGCTACAAAAGATGACAAAAAGGAACTTGGAGCAGCCAGAAGAAGTCAGTATTACATGAAATATGGGAATCCAAATTATGGAGGCAT
GAAAGGAATTCTTAGCAATTCATGGAAGCGAAGATATCATTCCCGTCGTATTCAGCGGGACGTGATCAAGAAGAGAGCCCTGATTGGGGA
TGACGTTGGCTTGACGTCGTATAAACATCGACATTCTGGGCTAGTGAATGTTCCCGAGGAACCCATTGAAGAGGAGGAAGAGGAGGAGGA
GGAGGAAGAGGAAGAGGAAGAAGAAGACCAGGACATGGATGCAGATGACAGAGTGGTGGTAGAGTACCACGAGGAGCTCCCGGCTCTCAA
GCAGCCCCGGGAGCGGAGCGCGTCTAGACGATCCAGTGCCAGCAGCTCAGACTCAGATGAAATGGACTATGATCTAGAACTGAAAATGAT
TTCCACGCCTTCACCAAAGAAAAGCATGAAAATGACTATGTATGCTGACGAAGTGGAATCTCAGTTGAAAAATATTAGGAACTCCATGAG
GGCAGATAGTGTATCTTCAAGCAATATCAAAAACCGAATTGGTAACAAATTACCACCTGAGAAATTTGCAGATGTCCGACATCTATTAGA
TGAGAAACGTCAGCACTCCCGTCCACGGCCACCAGTCAGCAGTACTAAATCAGATATACGCCAGCGGTTAGGAAAAAGACCACATTCTCC
GGAAAAGGCTTTTAGTAGTAACCCCGTCGTTCGGAGAGAGCCCTCTTCTGATGTGCATAGTAGGCTAGGTGTTCCCAGGCAGGATAGTAA
AGGCCTCTACGCCGATACTCGGGAGAAGAAATCAGAGCTCCCGAGTGAGGAAGGGAAGTCCCTGTGGGAGCTGGTGCTGGAACAGTTTGA
GGACCTCCTGGTGCGCATCCTGCTGCTGGCTGCCCTTGTCTCCTTTGTCCTGGCCTGGTTCGAGGAGGGCGAGGAGACCACGACCGCCTT
CGTGGAGCCCCTGGTCATCATGCTGATCCTCGTGGCCAACGCCATTGTGGGCGTGTGGCAGGAACGCAACGCCGAGAGTGCCATCGAGGC
CCTGAAGGAGTATGAGCCTGAGATGGGCAAGGTGATCCGCTCGGACCGCAAGGGCGTGCAGAGGATCCGTGCCCGGGACATCGTCCCAGG
GGACATTGTAGAAGTGGCAGTGGGGGACAAAGTGCCTGCTGACCTCCGCCTCATCGAGATCAAGTCCACCACGCTGCGAGTGGACCAGTC
CATCCTGACGGGTGAATCTGTGTCCGTGACCAAGCACACAGAGGCCATCCCAGACCCCAGAGCTGTGAACCAGGACAAGAAGAACATGCT
GTTTTCTGGCACCAATATCACATCGGGCAAAGCGGTGGGTGTGGCCGTGGCCACCGGCCTGCACACGGAGCTGGGCAAGATCCGGAGCCA
GATGGCGGCAGTCGAGCCCGAGCGGACGCCGCTGCAGCGCAAGCTGGACGAGTTTGGACGGCAGCTGTCCCACGCCATCTCTGTGATCTG
CGTGGCCGTGTGGGTCATCAACATCGGCCACTTCGCCGACCCGGCCCACGGTGGCTCCTGGCTGCGTGGCGCTGTCTACTACTTCAAGAT
CGCCGTGGCCCTGGCGGTGGCGGCCATCCCCGAGGGCCTCCCGGCTGTCATCACTACATGCCTGGCACTGGGCACGCGGCGCATGGCACG
CAAGAACGCCATCGTGCGAAGCCTGCCGTCCGTGGAGACCCTGGGCTGCACCTCAGTCATCTGCTCCGACAAGACGGGCACGCTCACCAC
CAATCAGATGTCTGTCTGCCGGATGTTCGTGGTAGCCGAGGCCGATGCGGGCTCCTGCCTTTTGCACGAGTTCACCATCTCGGGTACCAC
GTATACCCCCGAGGGCGAAGTGCGGCAGGGGGATCAGCCTGTGCGCTGCGGCCAGTTCGACGGGCTGGTGGAGCTGGCGACCATCTGCGC
CCTGTGCAACGACTCGGCTCTGGACTACAACGAGGCCAAGGGTGTGTATGAGAAGGTGGGAGAGGCCACGGAGACAGCTCTGACTTGCCT
GGTGGAGAAGATGAACGTGTTCGACACCGACCTGCAGGCTCTGTCCCGGGTGGAGCGAGCTGGCGCCTGTAACACGGTCATCAAGCAGCT
GATGCGGAAGGAGTTCACCCTGGAGTTCTCCCGAGACCGGAAATCCATGTCCGTGTACTGCACGCCCACCCGCCCTCACCCTACTGGCCA
GGGCAGCAAGATGTTTGTGAAGGGGGCTCCTGAGAGTGTGATCGAGCGCTGTAGCTCAGTCCGCGTGGGGAGCCGCACAGCACCCCTGAC
CCCCACCTCCAGGGAGCAGATCCTGGCAAAGATCCGGGATTGGGGCTCAGGCTCAGACACGCTGCGCTGCCTGGCACTGGCCACCCGGGA
CGCGCCCCCAAGGAAGGAGGACATGGAGCTGGACGACTGCAGCAAGTTTGTGCAGTACGAGACGGACCTGACCTTCGTGGGCTGCGTAGG
CATGCTGGACCCGCCGCGACCTGAGGTGGCTGCCTGCATCACACGCTGCTACCAGGCGGGCATCCGCGTGGTCATGATCACGGGGGATAA
CAAAGGCACTGCCGTGGCCATCTGCCGCAGGCTTGGCATCTTTGGGGACACGGAAGACGTGGCGGGCAAGGCCTACACGGGCCGCGAGTT
TGATGACCTCAGCCCCGAGCAGCAGCGCCAGGCCTGCCGCACCGCCCGCTGCTTCGCCCGCGTGGAGCCCGCACACAAGTCCCGCATCGT
GGAGAACCTGCAGTCCTTTAACGAGATCACTGCTATGACTGGCGATGGAGTGAACGACGCACCAGCCCTGAAGAAAGCAGAGATCGGCAT
CGCCATGGGCTCAGGCACGGCCGTGGCCAAGTCGGCGGCAGAGATGGTGCTGTCAGATGACAACTTTGCCTCCATCGTGGCTGCGGTGGA
GGAGGGCCGGGCCATCTACAGCAACATGAAGCAATTCATCCGCTACCTCATCTCCTCCAATGTTGGCGAGGTCGTCTGCATCTTCCTCAC
GGCAATTCTGGGCCTGCCCGAAGCCCTGATCCCTGTGCAGCTGCTCTGGGTGAACCTGGTGACAGACGGCCTACCTGCCACGGCTCTGGG
CTTCAACCCGCCAGACCTGGACATCATGGAGAAGCTGCCCCGGAGCCCCCGAGAAGCCCTCATCAGTGGCTGGCTCTTCTTCCGATACCT
GGCTATCGGAGTGTACGTAGGCCTGGCCACAGTGGCTGCCGCCACCTGGTGGTTTGTGTATGACGCCGAGGGACCTCACATCAACTTCTA
CCAGCTGAGGAACTTCCTGAAGTGCTCCGAAGACAACCCGCTCTTTGCCGGCATCGACTGTGAGGTGTTCGAGTCACGCTTCCCCACCAC
CATGGCCTTGTCCGTGCTCGTGACCATTGAAATGTGCAATGCCCTCAACAGCGTCTCGGAGAACCAGTCGCTGCTGCGGATGCCGCCCTG
GATGAACCCCTGGCTGCTGGTGGCTGTGGCCATGTCCATGGCCCTGCACTTCCTCATCCTGCTCGTGCCGCCCCTGCCTCTCATTTTCCA
GGTGACCCCACTGAGCGGGCGCCAGTGGGTGGTGGTGCTCCAGATATCTCTGCCTGTCATCCTGCTGGATGAGGCCCTCAAGTACCTGTC
CCGGAACCACATGCACGCCTGTCTTTATCCAGGCCTTCTCAGGACAGTCTCGCAGGCCTGGAGTAGGCAGCCGCTGACCACCTCTTGGAC
CCCAGACCACACCGGGTTGGCCTCTTTGAAGAAATGAGCCAGAAGTGAGCGCTGGGAACAGAGTGGAGTCTCCGGTGTGTACCTCAGACT
GATGGTGCCCATGTGTTCGCCTCCGCCCCCCACCCTTGCCACCACACTCGCCCACTTGCCCACCGGGTCCCGCCGGATAAATGACAGGCC
CGAGGTCAGAATGGCCATCCCCGGGCCCCGTCCTGGGGTCTCTGTCCCCACTTCCTTCTGGCCTGGGAGGTCTGTAATTCCTGTCTCCTG
GACTCTCCTGGGAAGTTCCCTGCTCTGCAGCTCTGGCCCAGGAGCTGCAGGCTGGGAGGGGGCAGCCAAGAAGCCGGAGCTGGCAGCATA
CCCAGAGATCCGGGGCCCCCCCACCCCCAAATCACGAGTGCAGCTGGAGCTTGCTCCCCCTTGTTCGGAAGCTGGACGTTCACTTGGTGA
CTGGTGCCTCTGCACTGACGGAGGACTCTGGGGGTCCTTCTTACCGGCTCTGACCTCTCTCTTCGTGCCTGGTCTGGGACTGGGTCAGCC
CTGGGGGATCAGAAGGGGCCATCTGGGCCCAGCTGTGTACAGCGAGGGTGGGCAGCCCCCTCCACTCCACTCTGCTTCCACAAAGTCGGC
TCCCGAGAGCTCGAGGCTGCTTCTGTTTATATGTGCAGGGCCCGGGCGGGTGAAGGGTCAGAGAGACGGACACAAGGAGCCGGCAGGAGG
GCGGAGCGAGGATGTCCTTTCCCGGGAGACAAGTCGGGAAAGCCTGGCTGGACTGCCTCAGCCCCGCGCGCCTCCTGGACTCAGGGTTCC
CCGTCCTGAGCTCGGGAGATGTTCAGAGTCACACTGCCGCCCGGTCTGCCACGCAGAGGTCCAACTTGCCACCCGCGTCCCTGGTACCTG
AGACCACCGACATCCTCAGGTTCCTGACCGTGGCGCCCTTCTACCCAGCCCAGTGTGCGGCCGCCGCGCTGTCTGCACAGCTGGGGGCCT
CTGAGCCTGGTGGGCTTCCTGGACTCTTGGCCTCACTCCTTGCCCCCTCCCCACGACACCCATGAGCCGAAAGGATGTCACTAAGGATGG
CTGATTCCCCAAGGGCACCCGCTCTCCCTCCCTCCCTGCTGGAGGAACACGTCATATCAGATGAGAGGAAGATGGCCTCTGATGGACAGA
ATTTTTCTCTTAACTCAGCTTTTGCTACTTTGGCAAAAACTAGCGAGGGGTAGCAGAAACCTGCACCAAGGATTGTCCCTATGTCTTGGC
CACTCCTAGAGCGTGTGCAGACTGATGATTTTATATGTAAATCAAGACTCACATCCCTTTCCTAGTCCCCCACATCCAAAGCCCCTCAGC
CTGCCTTGCAGACCAATGGGCTCCATGTTCTGTAGCCCCCTCCCCTACGCCTCACCCCTCCTCCCTCTCACAGGTTCTGGGCGGCCAGTG
AGAGAAACGCAGTGGGGGAGGCAGGGAGTCTGGTGCCTGCAGAGATTCTCTGCTTCTTTCCTGGGGGGAGGTGGGGAGGTCTTAGCAGGA

>11114_11114_1_C17orf85-ATP2A3_C17orf85_chr17_3717616_ENST00000389005_ATP2A3_chr17_3857004_ENST00000309890_length(amino acids)=1532AA_BP=343
MAAVRGLRVSVKAEAPAGPALGLPSPEAESGVDRGEPEPMEVEEGELEIVPVRRSLKELIPDTSRRYENKAGSFITGIDVTSKEAIEKKE
QRAKRFHFRSEVNLAQRNVALDRDMMKKAIPKVRLETIYICGVDEMSTQDVFSYFKEYPPAHIEWLDDTSCNVVWLDEMTATRALINMSS
LPAQDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEESLLRNDLRPANKLAKGNRLFMRFATKDDKKE
LGAARRSQYYMKYGNPNYGGMKGILSNSWKRRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEEEEEEEEED
QDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNI
KNRIGNKLPPEKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVHSRLGVPRQDSKGLYADTREK
KSELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEMG
KVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSG
KAVGVAVATGLHTELGKIRSQMAAVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVALAVAAI
PEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQ
GDQPVRCGQFDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRKEFTLEF
SRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDME
LDDCSKFVQYETDLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREFDDLSPEQQR
QACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNM
KQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRYLAIGVYVGLA
TVAAATWWFVYDAEGPHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMALSVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLVAV
AMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVLQISLPVILLDEALKYLSRNHMHACLYPGLLRTVSQAWSRQPLTTSWTPDHTGLASL

--------------------------------------------------------------
>11114_11114_2_C17orf85-ATP2A3_C17orf85_chr17_3717616_ENST00000389005_ATP2A3_chr17_3857004_ENST00000397041_length(transcript)=6084nt_BP=1655nt
CTCTCAGTGGTGCGGCCGGCAGGCAGCGATGGCGGCCGTACGGGGCCTGCGGGTGTCGGTGAAGGCGGAGGCCCCGGCGGGGCCGGCCCT
GGGGCTCCCGTCCCCTGAGGCGGAGTCCGGTGTTGACCGTGGCGAGCCGGAGCCCATGGAGGTGGAGGAGGGCGAGCTGGAAATCGTGCC
TGTGCGGCGCTCGCTCAAGGAACTGATCCCGGACACGAGCAGAAGATATGAAAACAAGGCTGGCAGCTTCATCACTGGAATTGATGTCAC
CTCCAAGGAAGCAATTGAAAAGAAAGAGCAGCGAGCCAAGCGCTTCCATTTTCGATCGGAAGTAAATCTTGCCCAAAGAAATGTAGCCTT
GGACCGAGACATGATGAAGAAAGCAATCCCCAAGGTGAGACTGGAGACAATCTATATTTGCGGAGTAGATGAGATGAGCACCCAAGATGT
CTTTTCCTATTTTAAAGAATATCCTCCAGCTCACATCGAATGGTTGGATGATACCTCCTGTAATGTAGTTTGGCTGGATGAAATGACAGC
CACACGAGCACTTATCAATATGAGCTCCCTGCCTGCACAGGATAAGATCAGAAGCAGGGATGCCAGTGAGGACAAGTCAGCTGAGAAAAG
GAAAAAAGACAAGCAGGAAGACAGTTCAGATGATGATGAAGCTGAAGAAGGAGAGGTTGAAGATGAGAACTCAAGTGATGTAGAGTTGGA
TACGTTGTCTCAGGTAGAAGAGGAGTCTTTGTTAAGAAACGATCTTCGTCCAGCTAACAAACTTGCTAAAGGAAATAGGTTATTCATGAG
ATTTGCTACAAAAGATGACAAAAAGGAACTTGGAGCAGCCAGAAGAAGTCAGTATTACATGAAATATGGGAATCCAAATTATGGAGGCAT
GAAAGGAATTCTTAGCAATTCATGGAAGCGAAGATATCATTCCCGTCGTATTCAGCGGGACGTGATCAAGAAGAGAGCCCTGATTGGGGA
TGACGTTGGCTTGACGTCGTATAAACATCGACATTCTGGGCTAGTGAATGTTCCCGAGGAACCCATTGAAGAGGAGGAAGAGGAGGAGGA
GGAGGAAGAGGAAGAGGAAGAAGAAGACCAGGACATGGATGCAGATGACAGAGTGGTGGTAGAGTACCACGAGGAGCTCCCGGCTCTCAA
GCAGCCCCGGGAGCGGAGCGCGTCTAGACGATCCAGTGCCAGCAGCTCAGACTCAGATGAAATGGACTATGATCTAGAACTGAAAATGAT
TTCCACGCCTTCACCAAAGAAAAGCATGAAAATGACTATGTATGCTGACGAAGTGGAATCTCAGTTGAAAAATATTAGGAACTCCATGAG
GGCAGATAGTGTATCTTCAAGCAATATCAAAAACCGAATTGGTAACAAATTACCACCTGAGAAATTTGCAGATGTCCGACATCTATTAGA
TGAGAAACGTCAGCACTCCCGTCCACGGCCACCAGTCAGCAGTACTAAATCAGATATACGCCAGCGGTTAGGAAAAAGACCACATTCTCC
GGAAAAGGCTTTTAGTAGTAACCCCGTCGTTCGGAGAGAGCCCTCTTCTGATGTGCATAGTAGGCTAGGTGTTCCCAGGCAGGATAGTAA
AGGCCTCTACGCCGATACTCGGGAGAAGAAATCAGAGCTCCCGAGTGAGGAAGGGAAGTCCCTGTGGGAGCTGGTGCTGGAACAGTTTGA
GGACCTCCTGGTGCGCATCCTGCTGCTGGCTGCCCTTGTCTCCTTTGTCCTGGCCTGGTTCGAGGAGGGCGAGGAGACCACGACCGCCTT
CGTGGAGCCCCTGGTCATCATGCTGATCCTCGTGGCCAACGCCATTGTGGGCGTGTGGCAGGAACGCAACGCCGAGAGTGCCATCGAGGC
CCTGAAGGAGTATGAGCCTGAGATGGGCAAGGTGATCCGCTCGGACCGCAAGGGCGTGCAGAGGATCCGTGCCCGGGACATCGTCCCAGG
GGACATTGTAGAAGTGGCAGTGGGGGACAAAGTGCCTGCTGACCTCCGCCTCATCGAGATCAAGTCCACCACGCTGCGAGTGGACCAGTC
CATCCTGACGGGTGAATCTGTGTCCGTGACCAAGCACACAGAGGCCATCCCAGACCCCAGAGCTGTGAACCAGGACAAGAAGAACATGCT
GTTTTCTGGCACCAATATCACATCGGGCAAAGCGGTGGGTGTGGCCGTGGCCACCGGCCTGCACACGGAGCTGGGCAAGATCCGGAGCCA
GATGGCGGCAGTCGAGCCCGAGCGGACGCCGCTGCAGCGCAAGCTGGACGAGTTTGGACGGCAGCTGTCCCACGCCATCTCTGTGATCTG
CGTGGCCGTGTGGGTCATCAACATCGGCCACTTCGCCGACCCGGCCCACGGTGGCTCCTGGCTGCGTGGCGCTGTCTACTACTTCAAGAT
CGCCGTGGCCCTGGCGGTGGCGGCCATCCCCGAGGGCCTCCCGGCTGTCATCACTACATGCCTGGCACTGGGCACGCGGCGCATGGCACG
CAAGAACGCCATCGTGCGAAGCCTGCCGTCCGTGGAGACCCTGGGCTGCACCTCAGTCATCTGCTCCGACAAGACGGGCACGCTCACCAC
CAATCAGATGTCTGTCTGCCGGATGTTCGTGGTAGCCGAGGCCGATGCGGGCTCCTGCCTTTTGCACGAGTTCACCATCTCGGGTACCAC
GTATACCCCCGAGGGCGAAGTGCGGCAGGGGGATCAGCCTGTGCGCTGCGGCCAGTTCGACGGGCTGGTGGAGCTGGCGACCATCTGCGC
CCTGTGCAACGACTCGGCTCTGGACTACAACGAGGCCAAGGGTGTGTATGAGAAGGTGGGAGAGGCCACGGAGACAGCTCTGACTTGCCT
GGTGGAGAAGATGAACGTGTTCGACACCGACCTGCAGGCTCTGTCCCGGGTGGAGCGAGCTGGCGCCTGTAACACGGTCATCAAGCAGCT
GATGCGGAAGGAGTTCACCCTGGAGTTCTCCCGAGACCGGAAATCCATGTCCGTGTACTGCACGCCCACCCGCCCTCACCCTACTGGCCA
GGGCAGCAAGATGTTTGTGAAGGGGGCTCCTGAGAGTGTGATCGAGCGCTGTAGCTCAGTCCGCGTGGGGAGCCGCACAGCACCCCTGAC
CCCCACCTCCAGGGAGCAGATCCTGGCAAAGATCCGGGATTGGGGCTCAGGCTCAGACACGCTGCGCTGCCTGGCACTGGCCACCCGGGA
CGCGCCCCCAAGGAAGGAGGACATGGAGCTGGACGACTGCAGCAAGTTTGTGCAGTACGAGACGGACCTGACCTTCGTGGGCTGCGTAGG
CATGCTGGACCCGCCGCGACCTGAGGTGGCTGCCTGCATCACACGCTGCTACCAGGCGGGCATCCGCGTGGTCATGATCACGGGGGATAA
CAAAGGCACTGCCGTGGCCATCTGCCGCAGGCTTGGCATCTTTGGGGACACGGAAGACGTGGCGGGCAAGGCCTACACGGGCCGCGAGTT
TGATGACCTCAGCCCCGAGCAGCAGCGCCAGGCCTGCCGCACCGCCCGCTGCTTCGCCCGCGTGGAGCCCGCACACAAGTCCCGCATCGT
GGAGAACCTGCAGTCCTTTAACGAGATCACTGCTATGACTGGCGATGGAGTGAACGACGCACCAGCCCTGAAGAAAGCAGAGATCGGCAT
CGCCATGGGCTCAGGCACGGCCGTGGCCAAGTCGGCGGCAGAGATGGTGCTGTCAGATGACAACTTTGCCTCCATCGTGGCTGCGGTGGA
GGAGGGCCGGGCCATCTACAGCAACATGAAGCAATTCATCCGCTACCTCATCTCCTCCAATGTTGGCGAGGTCGTCTGCATCTTCCTCAC
GGCAATTCTGGGCCTGCCCGAAGCCCTGATCCCTGTGCAGCTGCTCTGGGTGAACCTGGTGACAGACGGCCTACCTGCCACGGCTCTGGG
CTTCAACCCGCCAGACCTGGACATCATGGAGAAGCTGCCCCGGAGCCCCCGAGAAGCCCTCATCAGTGGCTGGCTCTTCTTCCGATACCT
GGCTATCGGAGTGTACGTAGGCCTGGCCACAGTGGCTGCCGCCACCTGGTGGTTTGTGTATGACGCCGAGGGACCTCACATCAACTTCTA
CCAGCTGAGGAACTTCCTGAAGTGCTCCGAAGACAACCCGCTCTTTGCCGGCATCGACTGTGAGGTGTTCGAGTCACGCTTCCCCACCAC
CATGGCCTTGTCCGTGCTCGTGACCATTGAAATGTGCAATGCCCTCAACAGCGTCTCGGAGAACCAGTCGCTGCTGCGGATGCCGCCCTG
GATGAACCCCTGGCTGCTGGTGGCTGTGGCCATGTCCATGGCCCTGCACTTCCTCATCCTGCTCGTGCCGCCCCTGCCTCTCATTTTCCA
GGTGACCCCACTGAGCGGGCGCCAGTGGGTGGTGGTGCTCCAGATATCTCTGCCTGTCATCCTGCTGGATGAGGCCCTCAAGTACCTGTC
CCGGAACCACATGCACGAAGAAATGAGCCAGAAGTGAGCGCTGGGAACAGAGTGGAGTCTCCGGTGTGTACCTCAGACTGATGGTGCCCA
TGTGTTCGCCTCCGCCCCCCACCCTTGCCACCACACTCGCCCACTTGCCCACCGGGTCCCGCCGGATAAATGACAGGCCCGAGGTCAGAA
TGGCCATCCCCGGGCCCCGTCCTGGGGTCTCTGTCCCCACTTCCTTCTGGCCTGGGAGGTCTGTAATTCCTGTCTCCTGGACTCTCCTGG
GAAGTTCCCTGCTCTGCAGCTCTGGCCCAGGAGCTGCAGGCTGGGAGGGGGCAGCCAAGAAGCCGGAGCTGGCAGCATACCCAGAGATCC
GGGGCCCCCCCACCCCCAAATCACGAGTGCAGCTGGAGCTTGCTCCCCCTTGTTCGGAAGCTGGACGTTCACTTGGTGACTGGTGCCTCT
GCACTGACGGAGGACTCTGGGGGTCCTTCTTACCGGCTCTGACCTCTCTCTTCGTGCCTGGTCTGGGACTGGGTCAGCCCTGGGGGATCA
GAAGGGGCCATCTGGGCCCAGCTGTGTACAGCGAGGGTGGGCAGCCCCCTCCACTCCACTCTGCTTCCACAAAGTCGGCTCCCGAGAGCT
CGAGGCTGCTTCTGTTTATATGTGCAGGGCCCGGGCGGGTGAAGGGTCAGAGAGACGGACACAAGGAGCCGGCAGGAGGGCGGAGCGAGG
ATGTCCTTTCCCGGGAGACAAGTCGGGAAAGCCTGGCTGGACTGCCTCAGCCCCGCGCGCCTCCTGGACTCAGGGTTCCCCGTCCTGAGC
TCGGGAGATGTTCAGAGTCACACTGCCGCCCGGTCTGCCACGCAGAGGTCCAACTTGCCACCCGCGTCCCTGGTACCTGAGACCACCGAC
ATCCTCAGGTTCCTGACCGTGGCGCCCTTCTACCCAGCCCAGTGTGCGGCCGCCGCGCTGTCTGCACAGCTGGGGGCCTCTGAGCCTGGT
GGGCTTCCTGGACTCTTGGCCTCACTCCTTGCCCCCTCCCCACGACACCCATGAGCCGAAAGGATGTCACTAAGGATGGCTGATTCCCCA
AGGGCACCCGCTCTCCCTCCCTCCCTGCTGGAGGAACACGTCATATCAGATGAGAGGAAGATGGCCTCTGATGGACAGAATTTTTCTCTT
AACTCAGCTTTTGCTACTTTGGCAAAAACTAGCGAGGGGTAGCAGAAACCTGCACCAAGGATTGTCCCTATGTCTTGGCCACTCCTAGAG
CGTGTGCAGACTGATGATTTTATATGTAAATCAAGACTCACATCCCTTTCCTAGTCCCCCACATCCAAAGCCCCTCAGCCTGCCTTGCAG
ACCAATGGGCTCCATGTTCTGTAGCCCCCTCCCCTACGCCTCACCCCTCCTCCCTCTCACAGGTTCTGGGCGGCCAGTGAGAGAAACGCA
GTGGGGGAGGCAGGGAGTCTGGTGCCTGCAGAGATTCTCTGCTTCTTTCCTGGGGGGAGGTGGGGAGGTCTTAGCAGGAGCGGGCCCTGT

>11114_11114_2_C17orf85-ATP2A3_C17orf85_chr17_3717616_ENST00000389005_ATP2A3_chr17_3857004_ENST00000397041_length(amino acids)=1502AA_BP=343
MAAVRGLRVSVKAEAPAGPALGLPSPEAESGVDRGEPEPMEVEEGELEIVPVRRSLKELIPDTSRRYENKAGSFITGIDVTSKEAIEKKE
QRAKRFHFRSEVNLAQRNVALDRDMMKKAIPKVRLETIYICGVDEMSTQDVFSYFKEYPPAHIEWLDDTSCNVVWLDEMTATRALINMSS
LPAQDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEESLLRNDLRPANKLAKGNRLFMRFATKDDKKE
LGAARRSQYYMKYGNPNYGGMKGILSNSWKRRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEEEEEEEEED
QDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEMDYDLELKMISTPSPKKSMKMTMYADEVESQLKNIRNSMRADSVSSSNI
KNRIGNKLPPEKFADVRHLLDEKRQHSRPRPPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVHSRLGVPRQDSKGLYADTREK
KSELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEMG
KVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSG
KAVGVAVATGLHTELGKIRSQMAAVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVALAVAAI
PEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQ
GDQPVRCGQFDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMRKEFTLEF
SRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDME
LDDCSKFVQYETDLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREFDDLSPEQQR
QACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNM
KQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRYLAIGVYVGLA
TVAAATWWFVYDAEGPHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMALSVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLVAV

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Fusion Gene PPI Analysis for NCBP3-ATP2A3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneATP2A3chr17:3717616chr17:3857004ENST00000309890022370_40039.3333333333333361030.0phospholamban 1
TgeneATP2A3chr17:3717616chr17:3857004ENST00000352011022370_40039.3333333333333361044.0phospholamban 1
TgeneATP2A3chr17:3717616chr17:3857004ENST00000359983023370_40039.3333333333333361053.0phospholamban 1
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397035023370_40039.3333333333333361266.3333333333333phospholamban 1
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397041021370_40039.3333333333333361000.0phospholamban 1
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397043021370_40039.333333333333336999.0phospholamban 1
TgeneATP2A3chr17:3717616chr17:3857004ENST00000309890022788_80839.3333333333333361030.0phospholamban 2
TgeneATP2A3chr17:3717616chr17:3857004ENST00000352011022788_80839.3333333333333361044.0phospholamban 2
TgeneATP2A3chr17:3717616chr17:3857004ENST00000359983023788_80839.3333333333333361053.0phospholamban 2
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397035023788_80839.3333333333333361266.3333333333333phospholamban 2
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397041021788_80839.3333333333333361000.0phospholamban 2
TgeneATP2A3chr17:3717616chr17:3857004ENST00000397043021788_80839.333333333333336999.0phospholamban 2


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for NCBP3-ATP2A3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NCBP3-ATP2A3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC0001430Adenoma1CTD_human
TgeneC0002152Alloxan Diabetes1CTD_human
TgeneC0011853Diabetes Mellitus, Experimental1CTD_human
TgeneC0011860Diabetes Mellitus, Non-Insulin-Dependent1CTD_human
TgeneC0038433Streptozotocin Diabetes1CTD_human
TgeneC0205646Adenoma, Basal Cell1CTD_human
TgeneC0205647Follicular adenoma1CTD_human
TgeneC0205648Adenoma, Microcystic1CTD_human
TgeneC0205649Adenoma, Monomorphic1CTD_human
TgeneC0205650Papillary adenoma1CTD_human
TgeneC0205651Adenoma, Trabecular1CTD_human