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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:LUC7L-CORIN (FusionGDB2 ID:HG55692TG10699)

Fusion Gene Summary for LUC7L-CORIN

check button Fusion gene summary
Fusion gene informationFusion gene name: LUC7L-CORIN
Fusion gene ID: hg55692tg10699
HgeneTgene
Gene symbol

LUC7L

CORIN

Gene ID

55692

10699

Gene nameLUC7 likecorin, serine peptidase
SynonymsLUC7B1|Luc7|SR+89|hLuc7B1ATC2|CRN|Lrp4|PEE5|TMPRSS10
Cytomap('LUC7L')('CORIN')

16p13.3

4p12

Type of geneprotein-codingprotein-coding
Descriptionputative RNA-binding protein Luc7-like 1putative SR protein LUC7B1sarcoplasmic reticulum protein LUC7B1atrial natriuretic peptide-converting enzymeheart-specific serine proteinase ATC2pro-ANP-convertasepro-ANP-converting enzymetransmembrane protease serine 10
Modification date2020032020200327
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000293872, ENST00000337351, 
ENST00000397780, ENST00000397783, 
ENST00000494366, 
Fusion gene scores* DoF score19 X 17 X 10=32308 X 9 X 8=576
# samples 259
** MAII scorelog2(25/3230*10)=-3.6915341649192
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/576*10)=-2.67807190511264
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: LUC7L [Title/Abstract] AND CORIN [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointLUC7L(249061)-CORIN(47667280), # samples:2
Anticipated loss of major functional domain due to fusion event.LUC7L-CORIN seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
LUC7L-CORIN seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
LUC7L-CORIN seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
LUC7L-CORIN seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
LUC7L-CORIN seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneCORIN

GO:0016486

peptide hormone processing

10880574


check buttonFusion gene breakpoints across LUC7L (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across CORIN (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-K4-A83P-01ALUC7Lchr16

249061

-CORINchr4

47667280

-


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Fusion Gene ORF analysis for LUC7L-CORIN

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000293872ENST00000515827LUC7Lchr16

249061

-CORINchr4

47667280

-
5CDS-intronENST00000337351ENST00000515827LUC7Lchr16

249061

-CORINchr4

47667280

-
5CDS-intronENST00000397780ENST00000515827LUC7Lchr16

249061

-CORINchr4

47667280

-
5CDS-intronENST00000397783ENST00000515827LUC7Lchr16

249061

-CORINchr4

47667280

-
Frame-shiftENST00000293872ENST00000273857LUC7Lchr16

249061

-CORINchr4

47667280

-
Frame-shiftENST00000293872ENST00000502252LUC7Lchr16

249061

-CORINchr4

47667280

-
Frame-shiftENST00000293872ENST00000504584LUC7Lchr16

249061

-CORINchr4

47667280

-
Frame-shiftENST00000293872ENST00000505909LUC7Lchr16

249061

-CORINchr4

47667280

-
Frame-shiftENST00000293872ENST00000508498LUC7Lchr16

249061

-CORINchr4

47667280

-
Frame-shiftENST00000337351ENST00000273857LUC7Lchr16

249061

-CORINchr4

47667280

-
Frame-shiftENST00000337351ENST00000502252LUC7Lchr16

249061

-CORINchr4

47667280

-
Frame-shiftENST00000337351ENST00000504584LUC7Lchr16

249061

-CORINchr4

47667280

-
Frame-shiftENST00000337351ENST00000505909LUC7Lchr16

249061

-CORINchr4

47667280

-
Frame-shiftENST00000337351ENST00000508498LUC7Lchr16

249061

-CORINchr4

47667280

-
Frame-shiftENST00000397783ENST00000273857LUC7Lchr16

249061

-CORINchr4

47667280

-
Frame-shiftENST00000397783ENST00000502252LUC7Lchr16

249061

-CORINchr4

47667280

-
Frame-shiftENST00000397783ENST00000504584LUC7Lchr16

249061

-CORINchr4

47667280

-
Frame-shiftENST00000397783ENST00000505909LUC7Lchr16

249061

-CORINchr4

47667280

-
Frame-shiftENST00000397783ENST00000508498LUC7Lchr16

249061

-CORINchr4

47667280

-
In-frameENST00000397780ENST00000273857LUC7Lchr16

249061

-CORINchr4

47667280

-
In-frameENST00000397780ENST00000502252LUC7Lchr16

249061

-CORINchr4

47667280

-
In-frameENST00000397780ENST00000504584LUC7Lchr16

249061

-CORINchr4

47667280

-
In-frameENST00000397780ENST00000505909LUC7Lchr16

249061

-CORINchr4

47667280

-
In-frameENST00000397780ENST00000508498LUC7Lchr16

249061

-CORINchr4

47667280

-
intron-3CDSENST00000494366ENST00000273857LUC7Lchr16

249061

-CORINchr4

47667280

-
intron-3CDSENST00000494366ENST00000502252LUC7Lchr16

249061

-CORINchr4

47667280

-
intron-3CDSENST00000494366ENST00000504584LUC7Lchr16

249061

-CORINchr4

47667280

-
intron-3CDSENST00000494366ENST00000505909LUC7Lchr16

249061

-CORINchr4

47667280

-
intron-3CDSENST00000494366ENST00000508498LUC7Lchr16

249061

-CORINchr4

47667280

-
intron-intronENST00000494366ENST00000515827LUC7Lchr16

249061

-CORINchr4

47667280

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000397780LUC7Lchr16249061-ENST00000273857CORINchr447667280-44719769962747583
ENST00000397780LUC7Lchr16249061-ENST00000508498CORINchr447667280-29879769962747583
ENST00000397780LUC7Lchr16249061-ENST00000502252CORINchr447667280-28099769962747583
ENST00000397780LUC7Lchr16249061-ENST00000505909CORINchr447667280-27489769962747583
ENST00000397780LUC7Lchr16249061-ENST00000504584CORINchr447667280-19909769961934312

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000397780ENST00000273857LUC7Lchr16249061-CORINchr447667280-0.0004707590.99952924
ENST00000397780ENST00000508498LUC7Lchr16249061-CORINchr447667280-0.0009891330.9990108
ENST00000397780ENST00000502252LUC7Lchr16249061-CORINchr447667280-0.0008747240.9991253
ENST00000397780ENST00000505909LUC7Lchr16249061-CORINchr447667280-0.000910240.9990897
ENST00000397780ENST00000504584LUC7Lchr16249061-CORINchr447667280-0.000450960.999549

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Fusion Genomic Features for LUC7L-CORIN


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for LUC7L-CORIN


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:249061/chr4:47667280)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLUC7Lchr16:249061chr4:47667280ENST00000293872-61087_177229372.0Coiled coilOntology_term=ECO:0000255
HgeneLUC7Lchr16:249061chr4:47667280ENST00000337351-6987_177229326.0Coiled coilOntology_term=ECO:0000255
HgeneLUC7Lchr16:249061chr4:47667280ENST00000397783-61087_177229424.0Coiled coilOntology_term=ECO:0000255
TgeneCORINchr16:249061chr4:47667280ENST00000273857922450_5734521043.0DomainFZ 2
TgeneCORINchr16:249061chr4:47667280ENST00000273857922579_6144521043.0DomainLDL-receptor class A 5
TgeneCORINchr16:249061chr4:47667280ENST00000273857922615_6534521043.0DomainLDL-receptor class A 6
TgeneCORINchr16:249061chr4:47667280ENST00000273857922654_6894521043.0DomainLDL-receptor class A 7
TgeneCORINchr16:249061chr4:47667280ENST00000273857922690_8014521043.0DomainNote=SRCR
TgeneCORINchr16:249061chr4:47667280ENST00000273857922802_10354521043.0DomainPeptidase S1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLUC7Lchr16:249061chr4:47667280ENST00000293872-610218_259229372.0Coiled coilOntology_term=ECO:0000255
HgeneLUC7Lchr16:249061chr4:47667280ENST00000337351-69218_259229326.0Coiled coilOntology_term=ECO:0000255
HgeneLUC7Lchr16:249061chr4:47667280ENST00000397783-610218_259229424.0Coiled coilOntology_term=ECO:0000255
HgeneLUC7Lchr16:249061chr4:47667280ENST00000293872-610243_362229372.0Compositional biasNote=Arg/Ser-rich
HgeneLUC7Lchr16:249061chr4:47667280ENST00000337351-69243_362229326.0Compositional biasNote=Arg/Ser-rich
HgeneLUC7Lchr16:249061chr4:47667280ENST00000397783-610243_362229424.0Compositional biasNote=Arg/Ser-rich
TgeneCORINchr16:249061chr4:47667280ENST00000273857922134_2594521043.0DomainFZ 1
TgeneCORINchr16:249061chr4:47667280ENST00000273857922268_3044521043.0DomainLDL-receptor class A 1
TgeneCORINchr16:249061chr4:47667280ENST00000273857922305_3404521043.0DomainLDL-receptor class A 2
TgeneCORINchr16:249061chr4:47667280ENST00000273857922341_3774521043.0DomainLDL-receptor class A 3
TgeneCORINchr16:249061chr4:47667280ENST00000273857922378_4154521043.0DomainLDL-receptor class A 4
TgeneCORINchr16:249061chr4:47667280ENST0000027385792226_294521043.0MotifNote=DDNN motif
TgeneCORINchr16:249061chr4:47667280ENST000002738579221_454521043.0Topological domainCytoplasmic
TgeneCORINchr16:249061chr4:47667280ENST0000027385792267_10424521043.0Topological domainExtracellular
TgeneCORINchr16:249061chr4:47667280ENST0000027385792246_664521043.0TransmembraneHelical%3B Signal-anchor for type II membrane protein


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Fusion Gene Sequence for LUC7L-CORIN


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>50360_50360_1_LUC7L-CORIN_LUC7L_chr16_249061_ENST00000397780_CORIN_chr4_47667280_ENST00000273857_length(transcript)=4471nt_BP=976nt
GTGGTTCATGGACCTCTGATTAGCTTGGGTTTTGCAGTCTCATTGCCACATGTATATGTGGAGCCAATGGCCTTTTGGTGCTCAGCTGTT
TACGTCTGACTCCTTGACTTCTTTGGTACAGTGATGGAGTCAGATCTCATTAAGTGTGATTCTCCATGATATAACTAGCCTCAAAAAAAT
GTGTATTCCACTCCAGTTGTAAATATCTTTAGATCAGCTTTTCATTGCATTTGATGGGGAGAACACAGAAATGATAGTCTGCAAATCATC
CAGGTGAATTGTTATACTAGTTATTTTTTGGTGGTTAATGTGATAATATTGTCTTATTTAAAACCACAAATGAATTTCAGGAGACGAAAC
CAGACAGAGGGTCAAGTTTACAGATGACCGTGTCTGCAAGAGTCACCTTCTGGACTGCTGCCCCCATGACATCCTGGCTGGGACGCGCAT
GGATTTAGGAGAATGTACCAAAATCCACGACTTGGCCCTCCGAGCAGATTATGAGATTGCAAGTAAAGAAAGAGACCTGTTTTTTGAATT
AGATGCAATGGATCACTTGGAGTCCTTTATTGCTGAATGTGATCGGAGAACTGAGCTCGCCAAGAAGCGGCTGGCAGAAACACAGGAGGA
AATCAGTGCGGAAGTTTCTGCAAAGGCAGAAAAAGTACATGAGTTAAATGAAGAAATAGGAAAACTCCTTGCTAAAGCCGAACAGCTAGG
GGCTGAAGGTAATGTGGATGAATCCCAGAAGATTCTTATGGAAGTGGAAAAAGTTCGTGCGAAGAAAAAAGAAGCTGAGGAAGAATACAG
AAATTCCATGCCTGCATCCAGTTTTCAGCAGCAAAAGCTGCGTGTCTGCGAGGTCTGTTCAGCCTACCTTGGTCTCCATGACAATGACCG
TCGCCTGGCAGACCACTTCGGTGGCAAGTTACACTTGGGGTTCATTCAGATCCGAGAGAAGCTTGATCAGTTGAGGGTCAATGTGAACCA
ATTACATTGGAACTCTGCATGAATTTGCCCTACAACAGTACAAGTTATCCAAATTATTTTGGCCACAGGACTCAAAAGGAAGCATCCATC
AGCTGGGAGTCTTCTCTTTTCCCTGCACTTGTTCAAACCAACTGTTATAAATACCTCATGTTCTTTTCTTGCACCATTTTGGTACCAAAA
TGTGATGTGAATACAGGCGAGCATATCCCTCCTTGCAGGGCATTGTGTGAACACTCTAAAGAACGCTGTGAGTCTGTTCTTGGGATTGTG
GGCCTACAGTGGCCTGAAGACACAGATTGCAGTCAATTTCCAGAGGAAAATTCAGACAATCAAACCTGCCTGATGCCTGATGAATATGTG
GAAGAATGCTCACCTAGTCATTTCAAGTGCCGCTCAGGACAGTGTGTTCTGGCTTCCAGAAGATGTGATGGCCAGGCCGACTGTGACGAT
GACAGTGATGAGGAAAACTGTGGTTGTAAAGAGAGAGATCTTTGGGAATGTCCATCCAATAAACAATGTTTGAAGCACACAGTGATCTGC
GATGGGTTCCCAGACTGCCCTGATTACATGGACGAGAAAAACTGCTCATTTTGCCAAGATGATGAGCTGGAATGTGCAAACCATGCGTGT
GTGTCACGTGACCTGTGGTGTGATGGTGAAGCCGACTGCTCAGACAGTTCAGATGAATGGGACTGTGTGACCCTCTCTATAAATGTGAAC
TCCTCTTCCTTTCTGATGGTTCACAGAGCTGCCACAGAACACCATGTGTGTGCAGATGGCTGGCAGGAGATATTGAGTCAGCTGGCCTGC
AAGCAGATGGGTTTAGGAGAACCATCTGTGACCAAATTGATACAGGAACAGGAGAAAGAGCCGCGGTGGCTGACATTACACTCCAACTGG
GAGAGCCTCAATGGGACCACTTTACATGAACTTCTAGTAAATGGGCAGTCTTGTGAGAGCAGAAGTAAAATTTCTCTTCTGTGTACTAAA
CAAGACTGTGGGCGCCGCCCTGCTGCCCGAATGAACAAAAGGATCCTTGGAGGTCGGACGAGTCGCCCTGGAAGGTGGCCATGGCAGTGT
TCTCTGCAGAGTGAACCCAGTGGACATATCTGTGGCTGTGTCCTCATTGCCAAGAAGTGGGTTCTGACAGTTGCCCACTGCTTCGAGGGG
AGAGAGAATGCTGCAGTTTGGAAAGTGGTGCTTGGCATCAACAATCTAGACCATCCATCAGTGTTCATGCAGACACGCTTTGTGAAGACC
ATCATCCTGCATCCCCGCTACAGTCGAGCAGTGGTGGACTATGACATCAGCATCGTTGAGCTGAGTGAAGACATCAGTGAGACTGGCTAC
GTCCGGCCTGTCTGCTTGCCCAACCCGGAGCAGTGGCTAGAGCCTGACACGTACTGCTATATCACAGGCTGGGGCCACATGGGCAATAAA
ATGCCATTTAAGCTGCAAGAGGGAGAGGTCCGCATTATTTCTCTGGAACATTGTCAGTCCTACTTTGACATGAAGACCATCACCACTCGG
ATGATATGTGCTGGCTATGAGTCTGGCACAGTTGATTCATGCATGGGTGACAGCGGTGGGCCTCTTGTTTGTGAGAAGCCTGGAGGACGG
TGGACATTATTTGGATTAACTTCATGGGGCTCCGTCTGCTTTTCCAAAGTCCTGGGGCCTGGCGTTTATAGTAATGTGTCATATTTCGTC
GAATGGATTAAAAGACAGATTTACATCCAGACCTTTCTCCTAAACTAATTATAAGGATGATCAGAGACTTTTGCCAGCTACACTAAAAGA
AAATGGCCTTCTTGACTGTGAAGAGCTGCCTGCAGAGAGCTGTACAGAAGCACTTTTCATGGACAGAAATGCTCAATCGTGCACTGCAAA
TTTGCATGTTTGTTTTGGACTAATTTTTTTCAATTTATTTTTTCACCTTCATTTTTCTCTTATTTCAAGTTCAATGAAAGACTTTACAAA
AGCAAACAAAGCAGACTTTGTCCTTTTGCCAGGCCTAACCATGACTGCAGCACAAAATTATCGACTCTGGCGAGATTTAAAATCAGGTGC
TACAGTAACAGGTTATGGAATGGTCTCTTTTATCCTATCACAAAAAAAGACATAGATATTTAGGCTGATTAATTATCTCTACCAGTTTTT
GTTTCTCAAGCTCAGTGCATAGTGGTAAATTTCAGTGTTAACATTGGAGACTTGCTTTTCTTTTTCTTTTTTTATACCCCACAATTCTTT
TTTATTACACTTCGAATTTTAGGGTACACGAGCACAACGTGCAGGTTAGTTACATATGTATACATGTGCCATGTTGGTGTGCTGAACCCA
GTAACTCGTCATTTGATTTATTAAAAGCCAAGATAATTTACATGTTTAAAGTATTTACTATTACCCCCTTCTAATGTTTGCATAATTCTG
AGAACTGATAAAAGACAGCAATAAAAGACCAGTGTCATCCATTTAGGTAGCAAGACATATTGAATGCAAAGTTCTTTAGATATCAATATT
AACACTTGACATTATTGGACCCCCCATTCTGGATGTATATCAAGATCATAATTTTATAGAAGAGTCTCTATAGAACTGTCCTCATAGCTG
GGTTTGTTCAGGATATATGAGTTGGCTGATTGAGACTGCAACAACTACATCTATATTTATGGGCAATATTTTGTTTTACTTATGTGGCAA
AGAACTGGATATTAAACTTTGCAAAAGAGAATTTAGATGAGAGATGCAATTTTTTAAAAAGAAAATTAATTTGCATCCCTCGTTTAATTA
AATTTATTTTTCAGTTTTCTTGCGTTCATCCATACCAACAAAGTCATAAAGAGCATATTTTAGAGCACAGTAAGACTTTGCATGGAGTAA
AACATTTTGTAATTTTCCTCAAAAGATGTTTAATATCTGGTTTCTTCTCATTGGTAATTAAAATTTTAGAAATGATTTTTAGCTCTAGGC
CACTTTACGCAACTCAATTTCTGAAGCAATTAGTGGTAAAAAGTATTTTTCCCCACTAAAAAACTTTAAAACACAAATCTTCATATATAC
TTAATTTAATTAGTCAGGCATCCATTTTGCCTTTTAAACAACTAGGATTCCCTACTAACCTCCACCAGCAACCTGGACTGCCTCAGCATT
CCAAATAGATACTACCTGCAATTTTATACATGTATTTTTGTATCTTTTCTGTGTGTAAACATAGTTGAAATTCAAAAAGTTGTAGCAATT
TCTATACTATTCATCTCCTGTCCTTCAGTTTGTATAAACCTAAGGAGAGTGTGAAATCCAGCAACTGAATTGTGGTCACGATTGTATGAA
AGTTCAAGAACATATGTCAGTTTTGTTACAGTTGTAGCTACATACTCAATGTATCAACTTTTAGCCTGCTCAACTTAGGCTCAGTGAAAT
ATATATATTATACTTATTTTAAATAATTCTTAATACAAATAAAATGGTAATGGTCTAATCA

>50360_50360_1_LUC7L-CORIN_LUC7L_chr16_249061_ENST00000397780_CORIN_chr4_47667280_ENST00000273857_length(amino acids)=583AA_BP=68
MELCMNLPYNSTSYPNYFGHRTQKEASISWESSLFPALVQTNCYKYLMFFSCTILVPKCDVNTGEHIPPCRALCEHSKERCESVLGIVGL
QWPEDTDCSQFPEENSDNQTCLMPDEYVEECSPSHFKCRSGQCVLASRRCDGQADCDDDSDEENCGCKERDLWECPSNKQCLKHTVICDG
FPDCPDYMDEKNCSFCQDDELECANHACVSRDLWCDGEADCSDSSDEWDCVTLSINVNSSSFLMVHRAATEHHVCADGWQEILSQLACKQ
MGLGEPSVTKLIQEQEKEPRWLTLHSNWESLNGTTLHELLVNGQSCESRSKISLLCTKQDCGRRPAARMNKRILGGRTSRPGRWPWQCSL
QSEPSGHICGCVLIAKKWVLTVAHCFEGRENAAVWKVVLGINNLDHPSVFMQTRFVKTIILHPRYSRAVVDYDISIVELSEDISETGYVR
PVCLPNPEQWLEPDTYCYITGWGHMGNKMPFKLQEGEVRIISLEHCQSYFDMKTITTRMICAGYESGTVDSCMGDSGGPLVCEKPGGRWT
LFGLTSWGSVCFSKVLGPGVYSNVSYFVEWIKRQIYIQTFLLN

--------------------------------------------------------------
>50360_50360_2_LUC7L-CORIN_LUC7L_chr16_249061_ENST00000397780_CORIN_chr4_47667280_ENST00000502252_length(transcript)=2809nt_BP=976nt
GTGGTTCATGGACCTCTGATTAGCTTGGGTTTTGCAGTCTCATTGCCACATGTATATGTGGAGCCAATGGCCTTTTGGTGCTCAGCTGTT
TACGTCTGACTCCTTGACTTCTTTGGTACAGTGATGGAGTCAGATCTCATTAAGTGTGATTCTCCATGATATAACTAGCCTCAAAAAAAT
GTGTATTCCACTCCAGTTGTAAATATCTTTAGATCAGCTTTTCATTGCATTTGATGGGGAGAACACAGAAATGATAGTCTGCAAATCATC
CAGGTGAATTGTTATACTAGTTATTTTTTGGTGGTTAATGTGATAATATTGTCTTATTTAAAACCACAAATGAATTTCAGGAGACGAAAC
CAGACAGAGGGTCAAGTTTACAGATGACCGTGTCTGCAAGAGTCACCTTCTGGACTGCTGCCCCCATGACATCCTGGCTGGGACGCGCAT
GGATTTAGGAGAATGTACCAAAATCCACGACTTGGCCCTCCGAGCAGATTATGAGATTGCAAGTAAAGAAAGAGACCTGTTTTTTGAATT
AGATGCAATGGATCACTTGGAGTCCTTTATTGCTGAATGTGATCGGAGAACTGAGCTCGCCAAGAAGCGGCTGGCAGAAACACAGGAGGA
AATCAGTGCGGAAGTTTCTGCAAAGGCAGAAAAAGTACATGAGTTAAATGAAGAAATAGGAAAACTCCTTGCTAAAGCCGAACAGCTAGG
GGCTGAAGGTAATGTGGATGAATCCCAGAAGATTCTTATGGAAGTGGAAAAAGTTCGTGCGAAGAAAAAAGAAGCTGAGGAAGAATACAG
AAATTCCATGCCTGCATCCAGTTTTCAGCAGCAAAAGCTGCGTGTCTGCGAGGTCTGTTCAGCCTACCTTGGTCTCCATGACAATGACCG
TCGCCTGGCAGACCACTTCGGTGGCAAGTTACACTTGGGGTTCATTCAGATCCGAGAGAAGCTTGATCAGTTGAGGGTCAATGTGAACCA
ATTACATTGGAACTCTGCATGAATTTGCCCTACAACAGTACAAGTTATCCAAATTATTTTGGCCACAGGACTCAAAAGGAAGCATCCATC
AGCTGGGAGTCTTCTCTTTTCCCTGCACTTGTTCAAACCAACTGTTATAAATACCTCATGTTCTTTTCTTGCACCATTTTGGTACCAAAA
TGTGATGTGAATACAGGCGAGCATATCCCTCCTTGCAGGGCATTGTGTGAACACTCTAAAGAACGCTGTGAGTCTGTTCTTGGGATTGTG
GGCCTACAGTGGCCTGAAGACACAGATTGCAGTCAATTTCCAGAGGAAAATTCAGACAATCAAACCTGCCTGATGCCTGATGAATATGTG
GAAGAATGCTCACCTAGTCATTTCAAGTGCCGCTCAGGACAGTGTGTTCTGGCTTCCAGAAGATGTGATGGCCAGGCCGACTGTGACGAT
GACAGTGATGAGGAAAACTGTGGTTGTAAAGAGAGAGATCTTTGGGAATGTCCATCCAATAAACAATGTTTGAAGCACACAGTGATCTGC
GATGGGTTCCCAGACTGCCCTGATTACATGGACGAGAAAAACTGCTCATTTTGCCAAGATGATGAGCTGGAATGTGCAAACCATGCGTGT
GTGTCACGTGACCTGTGGTGTGATGGTGAAGCCGACTGCTCAGACAGTTCAGATGAATGGGACTGTGTGACCCTCTCTATAAATGTGAAC
TCCTCTTCCTTTCTGATGGTTCACAGAGCTGCCACAGAACACCATGTGTGTGCAGATGGCTGGCAGGAGATATTGAGTCAGCTGGCCTGC
AAGCAGATGGGTTTAGGAGAACCATCTGTGACCAAATTGATACAGGAACAGGAGAAAGAGCCGCGGTGGCTGACATTACACTCCAACTGG
GAGAGCCTCAATGGGACCACTTTACATGAACTTCTAGTAAATGGGCAGTCTTGTGAGAGCAGAAGTAAAATTTCTCTTCTGTGTACTAAA
CAAGACTGTGGGCGCCGCCCTGCTGCCCGAATGAACAAAAGGATCCTTGGAGGTCGGACGAGTCGCCCTGGAAGGTGGCCATGGCAGTGT
TCTCTGCAGAGTGAACCCAGTGGACATATCTGTGGCTGTGTCCTCATTGCCAAGAAGTGGGTTCTGACAGTTGCCCACTGCTTCGAGGGG
AGAGAGAATGCTGCAGTTTGGAAAGTGGTGCTTGGCATCAACAATCTAGACCATCCATCAGTGTTCATGCAGACACGCTTTGTGAAGACC
ATCATCCTGCATCCCCGCTACAGTCGAGCAGTGGTGGACTATGACATCAGCATCGTTGAGCTGAGTGAAGACATCAGTGAGACTGGCTAC
GTCCGGCCTGTCTGCTTGCCCAACCCGGAGCAGTGGCTAGAGCCTGACACGTACTGCTATATCACAGGCTGGGGCCACATGGGCAATAAA
ATGCCATTTAAGCTGCAAGAGGGAGAGGTCCGCATTATTTCTCTGGAACATTGTCAGTCCTACTTTGACATGAAGACCATCACCACTCGG
ATGATATGTGCTGGCTATGAGTCTGGCACAGTTGATTCATGCATGGGTGACAGCGGTGGGCCTCTTGTTTGTGAGAAGCCTGGAGGACGG
TGGACATTATTTGGATTAACTTCATGGGGCTCCGTCTGCTTTTCCAAAGTCCTGGGGCCTGGCGTTTATAGTAATGTGTCATATTTCGTC
GAATGGATTAAAAGACAGATTTACATCCAGACCTTTCTCCTAAACTAATTATAAGGATGATCAGAGACTTTTGCCAGCTACACTAAAAGA
AAATGGCCTTCTTGACTGT

>50360_50360_2_LUC7L-CORIN_LUC7L_chr16_249061_ENST00000397780_CORIN_chr4_47667280_ENST00000502252_length(amino acids)=583AA_BP=68
MELCMNLPYNSTSYPNYFGHRTQKEASISWESSLFPALVQTNCYKYLMFFSCTILVPKCDVNTGEHIPPCRALCEHSKERCESVLGIVGL
QWPEDTDCSQFPEENSDNQTCLMPDEYVEECSPSHFKCRSGQCVLASRRCDGQADCDDDSDEENCGCKERDLWECPSNKQCLKHTVICDG
FPDCPDYMDEKNCSFCQDDELECANHACVSRDLWCDGEADCSDSSDEWDCVTLSINVNSSSFLMVHRAATEHHVCADGWQEILSQLACKQ
MGLGEPSVTKLIQEQEKEPRWLTLHSNWESLNGTTLHELLVNGQSCESRSKISLLCTKQDCGRRPAARMNKRILGGRTSRPGRWPWQCSL
QSEPSGHICGCVLIAKKWVLTVAHCFEGRENAAVWKVVLGINNLDHPSVFMQTRFVKTIILHPRYSRAVVDYDISIVELSEDISETGYVR
PVCLPNPEQWLEPDTYCYITGWGHMGNKMPFKLQEGEVRIISLEHCQSYFDMKTITTRMICAGYESGTVDSCMGDSGGPLVCEKPGGRWT
LFGLTSWGSVCFSKVLGPGVYSNVSYFVEWIKRQIYIQTFLLN

--------------------------------------------------------------
>50360_50360_3_LUC7L-CORIN_LUC7L_chr16_249061_ENST00000397780_CORIN_chr4_47667280_ENST00000504584_length(transcript)=1990nt_BP=976nt
GTGGTTCATGGACCTCTGATTAGCTTGGGTTTTGCAGTCTCATTGCCACATGTATATGTGGAGCCAATGGCCTTTTGGTGCTCAGCTGTT
TACGTCTGACTCCTTGACTTCTTTGGTACAGTGATGGAGTCAGATCTCATTAAGTGTGATTCTCCATGATATAACTAGCCTCAAAAAAAT
GTGTATTCCACTCCAGTTGTAAATATCTTTAGATCAGCTTTTCATTGCATTTGATGGGGAGAACACAGAAATGATAGTCTGCAAATCATC
CAGGTGAATTGTTATACTAGTTATTTTTTGGTGGTTAATGTGATAATATTGTCTTATTTAAAACCACAAATGAATTTCAGGAGACGAAAC
CAGACAGAGGGTCAAGTTTACAGATGACCGTGTCTGCAAGAGTCACCTTCTGGACTGCTGCCCCCATGACATCCTGGCTGGGACGCGCAT
GGATTTAGGAGAATGTACCAAAATCCACGACTTGGCCCTCCGAGCAGATTATGAGATTGCAAGTAAAGAAAGAGACCTGTTTTTTGAATT
AGATGCAATGGATCACTTGGAGTCCTTTATTGCTGAATGTGATCGGAGAACTGAGCTCGCCAAGAAGCGGCTGGCAGAAACACAGGAGGA
AATCAGTGCGGAAGTTTCTGCAAAGGCAGAAAAAGTACATGAGTTAAATGAAGAAATAGGAAAACTCCTTGCTAAAGCCGAACAGCTAGG
GGCTGAAGGTAATGTGGATGAATCCCAGAAGATTCTTATGGAAGTGGAAAAAGTTCGTGCGAAGAAAAAAGAAGCTGAGGAAGAATACAG
AAATTCCATGCCTGCATCCAGTTTTCAGCAGCAAAAGCTGCGTGTCTGCGAGGTCTGTTCAGCCTACCTTGGTCTCCATGACAATGACCG
TCGCCTGGCAGACCACTTCGGTGGCAAGTTACACTTGGGGTTCATTCAGATCCGAGAGAAGCTTGATCAGTTGAGGGTCAATGTGAACCA
ATTACATTGGAACTCTGCATGAATTTGCCCTACAACAGTACAAGTTATCCAAATTATTTTGGCCACAGGACTCAAAAGGAAGCATCCATC
AGCTGGGAGTCTTCTCTTTTCCCTGCACTTGTTCAAACCAACTGTTATAAATACCTCATGTTCTTTTCTTGCACCATTTTGGTACCAAAA
TGTGATGTGAATACAGGCGAGCATATCCCTCCTTGCAGGGCATTGTGTGAACACTCTAAAGAACGCTGTGAGTCTGTTCTTGGGATTGTG
GGCCTACAGTGGCCTGAAGACACAGATTGCAGTCAATTTCCAGAGGAAAATTCAGACAATCAAACCTGCCTGATGCCTGATGAATATGTG
GAAGAATGCTCACCTAGTCATTTCAAGTGCCGCTCAGGACAGTGTGTTCTGGCTTCCAGAAGATGTGATGGCCAGGCCGACTGTGACGAT
GACAGTGATGAGGAAAACTGTGGTTGTAAAGAGAGAGATCTTTGGGAATGTCCATCCAATAAACAATGTTTGAAGCACACAGTGATCTGC
GATGGGTTCCCAGACTGCCCTGATTACATGGACGAGAAAAACTGCTCATTTTGCCAAGATGATGAGCTGGAATGTGCAAACCATGCGTGT
GTGTCACGTGACCTGTGGTGTGATGGTGAAGCCGACTGCTCAGACAGTTCAGATGAATGGGACTGTGGTGAGCTACTTGTTTCTGCCATC
TGTTGTACTCTCTCATGCCTGTCAGCCACTGAAGCTGAATGGATCCTAAATTACTTCCTGGATTTTACTGACCAAGTTCATCTATTTTGT
TTTACTGTTATAAAAGCTGATAGTGCTGATCTATGTGTGTTATTTCCAACTCACAGAAAATTTCCCCACGAAGCTACTTCTCTATTTGAA
ATATCTATATTGTATGGAAAAACGTTTGGGTTCAAAATGTTGTAATCATATAATTGCTGGGAGAGGATTTAAAAACTCTTCATTAAAACC
CAACTTCAAT

>50360_50360_3_LUC7L-CORIN_LUC7L_chr16_249061_ENST00000397780_CORIN_chr4_47667280_ENST00000504584_length(amino acids)=312AA_BP=
MELCMNLPYNSTSYPNYFGHRTQKEASISWESSLFPALVQTNCYKYLMFFSCTILVPKCDVNTGEHIPPCRALCEHSKERCESVLGIVGL
QWPEDTDCSQFPEENSDNQTCLMPDEYVEECSPSHFKCRSGQCVLASRRCDGQADCDDDSDEENCGCKERDLWECPSNKQCLKHTVICDG
FPDCPDYMDEKNCSFCQDDELECANHACVSRDLWCDGEADCSDSSDEWDCGELLVSAICCTLSCLSATEAEWILNYFLDFTDQVHLFCFT
VIKADSADLCVLFPTHRKFPHEATSLFEISILYGKTFGFKML

--------------------------------------------------------------
>50360_50360_4_LUC7L-CORIN_LUC7L_chr16_249061_ENST00000397780_CORIN_chr4_47667280_ENST00000505909_length(transcript)=2748nt_BP=976nt
GTGGTTCATGGACCTCTGATTAGCTTGGGTTTTGCAGTCTCATTGCCACATGTATATGTGGAGCCAATGGCCTTTTGGTGCTCAGCTGTT
TACGTCTGACTCCTTGACTTCTTTGGTACAGTGATGGAGTCAGATCTCATTAAGTGTGATTCTCCATGATATAACTAGCCTCAAAAAAAT
GTGTATTCCACTCCAGTTGTAAATATCTTTAGATCAGCTTTTCATTGCATTTGATGGGGAGAACACAGAAATGATAGTCTGCAAATCATC
CAGGTGAATTGTTATACTAGTTATTTTTTGGTGGTTAATGTGATAATATTGTCTTATTTAAAACCACAAATGAATTTCAGGAGACGAAAC
CAGACAGAGGGTCAAGTTTACAGATGACCGTGTCTGCAAGAGTCACCTTCTGGACTGCTGCCCCCATGACATCCTGGCTGGGACGCGCAT
GGATTTAGGAGAATGTACCAAAATCCACGACTTGGCCCTCCGAGCAGATTATGAGATTGCAAGTAAAGAAAGAGACCTGTTTTTTGAATT
AGATGCAATGGATCACTTGGAGTCCTTTATTGCTGAATGTGATCGGAGAACTGAGCTCGCCAAGAAGCGGCTGGCAGAAACACAGGAGGA
AATCAGTGCGGAAGTTTCTGCAAAGGCAGAAAAAGTACATGAGTTAAATGAAGAAATAGGAAAACTCCTTGCTAAAGCCGAACAGCTAGG
GGCTGAAGGTAATGTGGATGAATCCCAGAAGATTCTTATGGAAGTGGAAAAAGTTCGTGCGAAGAAAAAAGAAGCTGAGGAAGAATACAG
AAATTCCATGCCTGCATCCAGTTTTCAGCAGCAAAAGCTGCGTGTCTGCGAGGTCTGTTCAGCCTACCTTGGTCTCCATGACAATGACCG
TCGCCTGGCAGACCACTTCGGTGGCAAGTTACACTTGGGGTTCATTCAGATCCGAGAGAAGCTTGATCAGTTGAGGGTCAATGTGAACCA
ATTACATTGGAACTCTGCATGAATTTGCCCTACAACAGTACAAGTTATCCAAATTATTTTGGCCACAGGACTCAAAAGGAAGCATCCATC
AGCTGGGAGTCTTCTCTTTTCCCTGCACTTGTTCAAACCAACTGTTATAAATACCTCATGTTCTTTTCTTGCACCATTTTGGTACCAAAA
TGTGATGTGAATACAGGCGAGCATATCCCTCCTTGCAGGGCATTGTGTGAACACTCTAAAGAACGCTGTGAGTCTGTTCTTGGGATTGTG
GGCCTACAGTGGCCTGAAGACACAGATTGCAGTCAATTTCCAGAGGAAAATTCAGACAATCAAACCTGCCTGATGCCTGATGAATATGTG
GAAGAATGCTCACCTAGTCATTTCAAGTGCCGCTCAGGACAGTGTGTTCTGGCTTCCAGAAGATGTGATGGCCAGGCCGACTGTGACGAT
GACAGTGATGAGGAAAACTGTGGTTGTAAAGAGAGAGATCTTTGGGAATGTCCATCCAATAAACAATGTTTGAAGCACACAGTGATCTGC
GATGGGTTCCCAGACTGCCCTGATTACATGGACGAGAAAAACTGCTCATTTTGCCAAGATGATGAGCTGGAATGTGCAAACCATGCGTGT
GTGTCACGTGACCTGTGGTGTGATGGTGAAGCCGACTGCTCAGACAGTTCAGATGAATGGGACTGTGTGACCCTCTCTATAAATGTGAAC
TCCTCTTCCTTTCTGATGGTTCACAGAGCTGCCACAGAACACCATGTGTGTGCAGATGGCTGGCAGGAGATATTGAGTCAGCTGGCCTGC
AAGCAGATGGGTTTAGGAGAACCATCTGTGACCAAATTGATACAGGAACAGGAGAAAGAGCCGCGGTGGCTGACATTACACTCCAACTGG
GAGAGCCTCAATGGGACCACTTTACATGAACTTCTAGTAAATGGGCAGTCTTGTGAGAGCAGAAGTAAAATTTCTCTTCTGTGTACTAAA
CAAGACTGTGGGCGCCGCCCTGCTGCCCGAATGAACAAAAGGATCCTTGGAGGTCGGACGAGTCGCCCTGGAAGGTGGCCATGGCAGTGT
TCTCTGCAGAGTGAACCCAGTGGACATATCTGTGGCTGTGTCCTCATTGCCAAGAAGTGGGTTCTGACAGTTGCCCACTGCTTCGAGGGG
AGAGAGAATGCTGCAGTTTGGAAAGTGGTGCTTGGCATCAACAATCTAGACCATCCATCAGTGTTCATGCAGACACGCTTTGTGAAGACC
ATCATCCTGCATCCCCGCTACAGTCGAGCAGTGGTGGACTATGACATCAGCATCGTTGAGCTGAGTGAAGACATCAGTGAGACTGGCTAC
GTCCGGCCTGTCTGCTTGCCCAACCCGGAGCAGTGGCTAGAGCCTGACACGTACTGCTATATCACAGGCTGGGGCCACATGGGCAATAAA
ATGCCATTTAAGCTGCAAGAGGGAGAGGTCCGCATTATTTCTCTGGAACATTGTCAGTCCTACTTTGACATGAAGACCATCACCACTCGG
ATGATATGTGCTGGCTATGAGTCTGGCACAGTTGATTCATGCATGGGTGACAGCGGTGGGCCTCTTGTTTGTGAGAAGCCTGGAGGACGG
TGGACATTATTTGGATTAACTTCATGGGGCTCCGTCTGCTTTTCCAAAGTCCTGGGGCCTGGCGTTTATAGTAATGTGTCATATTTCGTC
GAATGGATTAAAAGACAGATTTACATCCAGACCTTTCTCCTAAACTAA

>50360_50360_4_LUC7L-CORIN_LUC7L_chr16_249061_ENST00000397780_CORIN_chr4_47667280_ENST00000505909_length(amino acids)=583AA_BP=68
MELCMNLPYNSTSYPNYFGHRTQKEASISWESSLFPALVQTNCYKYLMFFSCTILVPKCDVNTGEHIPPCRALCEHSKERCESVLGIVGL
QWPEDTDCSQFPEENSDNQTCLMPDEYVEECSPSHFKCRSGQCVLASRRCDGQADCDDDSDEENCGCKERDLWECPSNKQCLKHTVICDG
FPDCPDYMDEKNCSFCQDDELECANHACVSRDLWCDGEADCSDSSDEWDCVTLSINVNSSSFLMVHRAATEHHVCADGWQEILSQLACKQ
MGLGEPSVTKLIQEQEKEPRWLTLHSNWESLNGTTLHELLVNGQSCESRSKISLLCTKQDCGRRPAARMNKRILGGRTSRPGRWPWQCSL
QSEPSGHICGCVLIAKKWVLTVAHCFEGRENAAVWKVVLGINNLDHPSVFMQTRFVKTIILHPRYSRAVVDYDISIVELSEDISETGYVR
PVCLPNPEQWLEPDTYCYITGWGHMGNKMPFKLQEGEVRIISLEHCQSYFDMKTITTRMICAGYESGTVDSCMGDSGGPLVCEKPGGRWT
LFGLTSWGSVCFSKVLGPGVYSNVSYFVEWIKRQIYIQTFLLN

--------------------------------------------------------------
>50360_50360_5_LUC7L-CORIN_LUC7L_chr16_249061_ENST00000397780_CORIN_chr4_47667280_ENST00000508498_length(transcript)=2987nt_BP=976nt
GTGGTTCATGGACCTCTGATTAGCTTGGGTTTTGCAGTCTCATTGCCACATGTATATGTGGAGCCAATGGCCTTTTGGTGCTCAGCTGTT
TACGTCTGACTCCTTGACTTCTTTGGTACAGTGATGGAGTCAGATCTCATTAAGTGTGATTCTCCATGATATAACTAGCCTCAAAAAAAT
GTGTATTCCACTCCAGTTGTAAATATCTTTAGATCAGCTTTTCATTGCATTTGATGGGGAGAACACAGAAATGATAGTCTGCAAATCATC
CAGGTGAATTGTTATACTAGTTATTTTTTGGTGGTTAATGTGATAATATTGTCTTATTTAAAACCACAAATGAATTTCAGGAGACGAAAC
CAGACAGAGGGTCAAGTTTACAGATGACCGTGTCTGCAAGAGTCACCTTCTGGACTGCTGCCCCCATGACATCCTGGCTGGGACGCGCAT
GGATTTAGGAGAATGTACCAAAATCCACGACTTGGCCCTCCGAGCAGATTATGAGATTGCAAGTAAAGAAAGAGACCTGTTTTTTGAATT
AGATGCAATGGATCACTTGGAGTCCTTTATTGCTGAATGTGATCGGAGAACTGAGCTCGCCAAGAAGCGGCTGGCAGAAACACAGGAGGA
AATCAGTGCGGAAGTTTCTGCAAAGGCAGAAAAAGTACATGAGTTAAATGAAGAAATAGGAAAACTCCTTGCTAAAGCCGAACAGCTAGG
GGCTGAAGGTAATGTGGATGAATCCCAGAAGATTCTTATGGAAGTGGAAAAAGTTCGTGCGAAGAAAAAAGAAGCTGAGGAAGAATACAG
AAATTCCATGCCTGCATCCAGTTTTCAGCAGCAAAAGCTGCGTGTCTGCGAGGTCTGTTCAGCCTACCTTGGTCTCCATGACAATGACCG
TCGCCTGGCAGACCACTTCGGTGGCAAGTTACACTTGGGGTTCATTCAGATCCGAGAGAAGCTTGATCAGTTGAGGGTCAATGTGAACCA
ATTACATTGGAACTCTGCATGAATTTGCCCTACAACAGTACAAGTTATCCAAATTATTTTGGCCACAGGACTCAAAAGGAAGCATCCATC
AGCTGGGAGTCTTCTCTTTTCCCTGCACTTGTTCAAACCAACTGTTATAAATACCTCATGTTCTTTTCTTGCACCATTTTGGTACCAAAA
TGTGATGTGAATACAGGCGAGCATATCCCTCCTTGCAGGGCATTGTGTGAACACTCTAAAGAACGCTGTGAGTCTGTTCTTGGGATTGTG
GGCCTACAGTGGCCTGAAGACACAGATTGCAGTCAATTTCCAGAGGAAAATTCAGACAATCAAACCTGCCTGATGCCTGATGAATATGTG
GAAGAATGCTCACCTAGTCATTTCAAGTGCCGCTCAGGACAGTGTGTTCTGGCTTCCAGAAGATGTGATGGCCAGGCCGACTGTGACGAT
GACAGTGATGAGGAAAACTGTGGTTGTAAAGAGAGAGATCTTTGGGAATGTCCATCCAATAAACAATGTTTGAAGCACACAGTGATCTGC
GATGGGTTCCCAGACTGCCCTGATTACATGGACGAGAAAAACTGCTCATTTTGCCAAGATGATGAGCTGGAATGTGCAAACCATGCGTGT
GTGTCACGTGACCTGTGGTGTGATGGTGAAGCCGACTGCTCAGACAGTTCAGATGAATGGGACTGTGTGACCCTCTCTATAAATGTGAAC
TCCTCTTCCTTTCTGATGGTTCACAGAGCTGCCACAGAACACCATGTGTGTGCAGATGGCTGGCAGGAGATATTGAGTCAGCTGGCCTGC
AAGCAGATGGGTTTAGGAGAACCATCTGTGACCAAATTGATACAGGAACAGGAGAAAGAGCCGCGGTGGCTGACATTACACTCCAACTGG
GAGAGCCTCAATGGGACCACTTTACATGAACTTCTAGTAAATGGGCAGTCTTGTGAGAGCAGAAGTAAAATTTCTCTTCTGTGTACTAAA
CAAGACTGTGGGCGCCGCCCTGCTGCCCGAATGAACAAAAGGATCCTTGGAGGTCGGACGAGTCGCCCTGGAAGGTGGCCATGGCAGTGT
TCTCTGCAGAGTGAACCCAGTGGACATATCTGTGGCTGTGTCCTCATTGCCAAGAAGTGGGTTCTGACAGTTGCCCACTGCTTCGAGGGG
AGAGAGAATGCTGCAGTTTGGAAAGTGGTGCTTGGCATCAACAATCTAGACCATCCATCAGTGTTCATGCAGACACGCTTTGTGAAGACC
ATCATCCTGCATCCCCGCTACAGTCGAGCAGTGGTGGACTATGACATCAGCATCGTTGAGCTGAGTGAAGACATCAGTGAGACTGGCTAC
GTCCGGCCTGTCTGCTTGCCCAACCCGGAGCAGTGGCTAGAGCCTGACACGTACTGCTATATCACAGGCTGGGGCCACATGGGCAATAAA
ATGCCATTTAAGCTGCAAGAGGGAGAGGTCCGCATTATTTCTCTGGAACATTGTCAGTCCTACTTTGACATGAAGACCATCACCACTCGG
ATGATATGTGCTGGCTATGAGTCTGGCACAGTTGATTCATGCATGGGTGACAGCGGTGGGCCTCTTGTTTGTGAGAAGCCTGGAGGACGG
TGGACATTATTTGGATTAACTTCATGGGGCTCCGTCTGCTTTTCCAAAGTCCTGGGGCCTGGCGTTTATAGTAATGTGTCATATTTCGTC
GAATGGATTAAAAGACAGATTTACATCCAGACCTTTCTCCTAAACTAATTATAAGGATGATCAGAGACTTTTGCCAGCTACACTAAAAGA
AAATGGCCTTCTTGACTGTGAAGAGCTGCCTGCAGAGAGCTGTACAGAAGCACTTTTCATGGACAGAAATGCTCAATCGTGCACTGCAAA
TTTGCATGTTTGTTTTGGACTAATTTTTTTCAATTTATTTTTTCACCTTCATTTTTCTCTTATTTCAAGTTCAATGAAAGACTTTACAAA
AGCAAACAAAGCAGACT

>50360_50360_5_LUC7L-CORIN_LUC7L_chr16_249061_ENST00000397780_CORIN_chr4_47667280_ENST00000508498_length(amino acids)=583AA_BP=68
MELCMNLPYNSTSYPNYFGHRTQKEASISWESSLFPALVQTNCYKYLMFFSCTILVPKCDVNTGEHIPPCRALCEHSKERCESVLGIVGL
QWPEDTDCSQFPEENSDNQTCLMPDEYVEECSPSHFKCRSGQCVLASRRCDGQADCDDDSDEENCGCKERDLWECPSNKQCLKHTVICDG
FPDCPDYMDEKNCSFCQDDELECANHACVSRDLWCDGEADCSDSSDEWDCVTLSINVNSSSFLMVHRAATEHHVCADGWQEILSQLACKQ
MGLGEPSVTKLIQEQEKEPRWLTLHSNWESLNGTTLHELLVNGQSCESRSKISLLCTKQDCGRRPAARMNKRILGGRTSRPGRWPWQCSL
QSEPSGHICGCVLIAKKWVLTVAHCFEGRENAAVWKVVLGINNLDHPSVFMQTRFVKTIILHPRYSRAVVDYDISIVELSEDISETGYVR
PVCLPNPEQWLEPDTYCYITGWGHMGNKMPFKLQEGEVRIISLEHCQSYFDMKTITTRMICAGYESGTVDSCMGDSGGPLVCEKPGGRWT
LFGLTSWGSVCFSKVLGPGVYSNVSYFVEWIKRQIYIQTFLLN

--------------------------------------------------------------

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Fusion Gene PPI Analysis for LUC7L-CORIN


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for LUC7L-CORIN


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for LUC7L-CORIN


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC0032914Pre-Eclampsia1CTD_human;ORPHANET
TgeneC3281288PREECLAMPSIA/ECLAMPSIA 51UNIPROT