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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ERGIC1-RANBP17 (FusionGDB2 ID:HG57222TG64901)

Fusion Gene Summary for ERGIC1-RANBP17

check button Fusion gene summary
Fusion gene informationFusion gene name: ERGIC1-RANBP17
Fusion gene ID: hg57222tg64901
HgeneTgene
Gene symbol

ERGIC1

RANBP17

Gene ID

57222

64901

Gene nameendoplasmic reticulum-golgi intermediate compartment 1RAN binding protein 17
SynonymsAMCN|ERGIC-32|ERGIC32|NET24-
Cytomap('ERGIC1')('RANBP17')

5q35.1

5q35.1

Type of geneprotein-codingprotein-coding
Descriptionendoplasmic reticulum-Golgi intermediate compartment protein 1ER-Golgi intermediate compartment 32 kDa proteinendoplasmic reticulum-golgi intermediate compartment (ERGIC) 1endoplasmic reticulum-golgi intermediate compartment 32 kDa proteinran-binding protein 17
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000326654, ENST00000393784, 
ENST00000523291, ENST00000519860, 
Fusion gene scores* DoF score19 X 21 X 9=35916 X 9 X 4=216
# samples 258
** MAII scorelog2(25/3591*10)=-3.84438565300257
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/216*10)=-1.43295940727611
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ERGIC1 [Title/Abstract] AND RANBP17 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointERGIC1(172341841)-RANBP17(170720887), # samples:5
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneERGIC1

GO:0006888

ER to Golgi vesicle-mediated transport

15308636


check buttonFusion gene breakpoints across ERGIC1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across RANBP17 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-33-6737-01AERGIC1chr5

172341840

+RANBP17chr5

170720886

+
ChimerDB4LUSCTCGA-33-6737-01AERGIC1chr5

172341841

-RANBP17chr5

170720887

+
ChimerDB4LUSCTCGA-33-6737-01AERGIC1chr5

172341841

+RANBP17chr5

170720887

+
ChimerDB4LUSCTCGA-33-6737ERGIC1chr5

172341841

+RANBP17chr5

170720886

+
ChimerDB4LUSCTCGA-33-6738-01AERGIC1chr5

172341841

-RANBP17chr5

170720887

+
ChimerDB4LUSCTCGA-33-6738-01AERGIC1chr5

172341841

+RANBP17chr5

170720887

+
ChimerDB4LUSCTCGA-33-6738ERGIC1chr5

172341841

+RANBP17chr5

170720886

+
ChimerDB4LUSCTCGA-33-6738ERGIC1chr5

172341841

+RANBP17chr5

170720887

+
ChimerDB4OVTCGA-25-2400-01AERGIC1chr5

172351112

+RANBP17chr5

170588411

+
ChimerDB4OVTCGA-25-2400-01AERGIC1chr5

172351112

+RANBP17chr5

170597134

+


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Fusion Gene ORF analysis for ERGIC1-RANBP17

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000326654ENST00000521759ERGIC1chr5

172341840

+RANBP17chr5

170720886

+
5CDS-3UTRENST00000326654ENST00000521759ERGIC1chr5

172341841

+RANBP17chr5

170720887

+
5CDS-3UTRENST00000326654ENST00000521759ERGIC1chr5

172341841

+RANBP17chr5

170720886

+
5CDS-3UTRENST00000393784ENST00000521759ERGIC1chr5

172341840

+RANBP17chr5

170720886

+
5CDS-3UTRENST00000393784ENST00000521759ERGIC1chr5

172341841

+RANBP17chr5

170720887

+
5CDS-3UTRENST00000393784ENST00000521759ERGIC1chr5

172341841

+RANBP17chr5

170720886

+
5CDS-3UTRENST00000393784ENST00000521759ERGIC1chr5

172351112

+RANBP17chr5

170597134

+
5CDS-3UTRENST00000523291ENST00000521759ERGIC1chr5

172341840

+RANBP17chr5

170720886

+
5CDS-3UTRENST00000523291ENST00000521759ERGIC1chr5

172341841

+RANBP17chr5

170720887

+
5CDS-3UTRENST00000523291ENST00000521759ERGIC1chr5

172341841

+RANBP17chr5

170720886

+
5CDS-intronENST00000393784ENST00000521759ERGIC1chr5

172351112

+RANBP17chr5

170588411

+
5CDS-intronENST00000393784ENST00000523189ERGIC1chr5

172351112

+RANBP17chr5

170588411

+
Frame-shiftENST00000326654ENST00000523189ERGIC1chr5

172341840

+RANBP17chr5

170720886

+
Frame-shiftENST00000326654ENST00000523189ERGIC1chr5

172341841

+RANBP17chr5

170720887

+
Frame-shiftENST00000326654ENST00000523189ERGIC1chr5

172341841

+RANBP17chr5

170720886

+
In-frameENST00000393784ENST00000523189ERGIC1chr5

172341840

+RANBP17chr5

170720886

+
In-frameENST00000393784ENST00000523189ERGIC1chr5

172341841

+RANBP17chr5

170720887

+
In-frameENST00000393784ENST00000523189ERGIC1chr5

172341841

+RANBP17chr5

170720886

+
In-frameENST00000393784ENST00000523189ERGIC1chr5

172351112

+RANBP17chr5

170597134

+
In-frameENST00000523291ENST00000523189ERGIC1chr5

172341840

+RANBP17chr5

170720886

+
In-frameENST00000523291ENST00000523189ERGIC1chr5

172341841

+RANBP17chr5

170720887

+
In-frameENST00000523291ENST00000523189ERGIC1chr5

172341841

+RANBP17chr5

170720886

+
intron-3CDSENST00000326654ENST00000523189ERGIC1chr5

172351112

+RANBP17chr5

170597134

+
intron-3CDSENST00000519860ENST00000523189ERGIC1chr5

172341840

+RANBP17chr5

170720886

+
intron-3CDSENST00000519860ENST00000523189ERGIC1chr5

172341841

+RANBP17chr5

170720887

+
intron-3CDSENST00000519860ENST00000523189ERGIC1chr5

172341841

+RANBP17chr5

170720886

+
intron-3CDSENST00000519860ENST00000523189ERGIC1chr5

172351112

+RANBP17chr5

170597134

+
intron-3CDSENST00000523291ENST00000523189ERGIC1chr5

172351112

+RANBP17chr5

170597134

+
intron-3UTRENST00000326654ENST00000521759ERGIC1chr5

172351112

+RANBP17chr5

170597134

+
intron-3UTRENST00000519860ENST00000521759ERGIC1chr5

172341840

+RANBP17chr5

170720886

+
intron-3UTRENST00000519860ENST00000521759ERGIC1chr5

172341841

+RANBP17chr5

170720887

+
intron-3UTRENST00000519860ENST00000521759ERGIC1chr5

172341841

+RANBP17chr5

170720886

+
intron-3UTRENST00000519860ENST00000521759ERGIC1chr5

172351112

+RANBP17chr5

170597134

+
intron-3UTRENST00000523291ENST00000521759ERGIC1chr5

172351112

+RANBP17chr5

170597134

+
intron-intronENST00000326654ENST00000521759ERGIC1chr5

172351112

+RANBP17chr5

170588411

+
intron-intronENST00000326654ENST00000523189ERGIC1chr5

172351112

+RANBP17chr5

170588411

+
intron-intronENST00000519860ENST00000521759ERGIC1chr5

172351112

+RANBP17chr5

170588411

+
intron-intronENST00000519860ENST00000523189ERGIC1chr5

172351112

+RANBP17chr5

170588411

+
intron-intronENST00000523291ENST00000521759ERGIC1chr5

172351112

+RANBP17chr5

170588411

+
intron-intronENST00000523291ENST00000523189ERGIC1chr5

172351112

+RANBP17chr5

170588411

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000393784ERGIC1chr5172341841+ENST00000523189RANBP17chr5170720887+199551464837257
ENST00000523291ERGIC1chr5172341841+ENST00000523189RANBP17chr5170720887+18593783701232
ENST00000393784ERGIC1chr5172341841+ENST00000523189RANBP17chr5170720886+199551464837257
ENST00000523291ERGIC1chr5172341841+ENST00000523189RANBP17chr5170720886+18593783701232
ENST00000393784ERGIC1chr5172351112+ENST00000523189RANBP17chr5170597134+3333619642175703
ENST00000393784ERGIC1chr5172341840+ENST00000523189RANBP17chr5170720886+199551464837257
ENST00000523291ERGIC1chr5172341840+ENST00000523189RANBP17chr5170720886+18593783701232

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000393784ENST00000523189ERGIC1chr5172341841+RANBP17chr5170720887+0.0025613730.99743855
ENST00000523291ENST00000523189ERGIC1chr5172341841+RANBP17chr5170720887+0.0023271540.99767286
ENST00000393784ENST00000523189ERGIC1chr5172341841+RANBP17chr5170720886+0.0025613730.99743855
ENST00000523291ENST00000523189ERGIC1chr5172341841+RANBP17chr5170720886+0.0023271540.99767286
ENST00000393784ENST00000523189ERGIC1chr5172351112+RANBP17chr5170597134+0.0014620160.998538
ENST00000393784ENST00000523189ERGIC1chr5172341840+RANBP17chr5170720886+0.0025613730.99743855
ENST00000523291ENST00000523189ERGIC1chr5172341840+RANBP17chr5170720886+0.0023271540.99767286

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Fusion Genomic Features for ERGIC1-RANBP17


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ERGIC1chr5172351112+RANBP17chr5170597133+0.001296660.99870336
ERGIC1chr5172341841+RANBP17chr5170720886+2.15E-070.99999976
ERGIC1chr5172341841+RANBP17chr5170720886+2.15E-070.99999976
ERGIC1chr5172351112+RANBP17chr5170597133+0.001296660.99870336
ERGIC1chr5172341841+RANBP17chr5170720886+2.15E-070.99999976
ERGIC1chr5172341841+RANBP17chr5170720886+2.15E-070.99999976

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ERGIC1-RANBP17


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:172341841/chr5:170720887)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneERGIC1chr5:172341840chr5:170720886ENST00000393784+5101_26125291.0Topological domainCytoplasmic
HgeneERGIC1chr5:172341841chr5:170720886ENST00000393784+5101_26125291.0Topological domainCytoplasmic
HgeneERGIC1chr5:172341841chr5:170720887ENST00000393784+5101_26125291.0Topological domainCytoplasmic
HgeneERGIC1chr5:172351112chr5:170597134ENST00000393784+6101_26160291.0Topological domainCytoplasmic
HgeneERGIC1chr5:172341840chr5:170720886ENST00000393784+51027_47125291.0TransmembraneHelical
HgeneERGIC1chr5:172341841chr5:170720886ENST00000393784+51027_47125291.0TransmembraneHelical
HgeneERGIC1chr5:172341841chr5:170720887ENST00000393784+51027_47125291.0TransmembraneHelical
HgeneERGIC1chr5:172351112chr5:170597134ENST00000393784+61027_47160291.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneERGIC1chr5:172341840chr5:170720886ENST00000326654+131_260160.0Topological domainCytoplasmic
HgeneERGIC1chr5:172341840chr5:170720886ENST00000326654+13276_2900160.0Topological domainCytoplasmic
HgeneERGIC1chr5:172341840chr5:170720886ENST00000326654+1348_2540160.0Topological domainLumenal
HgeneERGIC1chr5:172341840chr5:170720886ENST00000393784+510276_290125291.0Topological domainCytoplasmic
HgeneERGIC1chr5:172341840chr5:170720886ENST00000393784+51048_254125291.0Topological domainLumenal
HgeneERGIC1chr5:172341841chr5:170720886ENST00000326654+131_260160.0Topological domainCytoplasmic
HgeneERGIC1chr5:172341841chr5:170720886ENST00000326654+13276_2900160.0Topological domainCytoplasmic
HgeneERGIC1chr5:172341841chr5:170720886ENST00000326654+1348_2540160.0Topological domainLumenal
HgeneERGIC1chr5:172341841chr5:170720886ENST00000393784+510276_290125291.0Topological domainCytoplasmic
HgeneERGIC1chr5:172341841chr5:170720886ENST00000393784+51048_254125291.0Topological domainLumenal
HgeneERGIC1chr5:172341841chr5:170720887ENST00000326654+131_260160.0Topological domainCytoplasmic
HgeneERGIC1chr5:172341841chr5:170720887ENST00000326654+13276_2900160.0Topological domainCytoplasmic
HgeneERGIC1chr5:172341841chr5:170720887ENST00000326654+1348_2540160.0Topological domainLumenal
HgeneERGIC1chr5:172341841chr5:170720887ENST00000393784+510276_290125291.0Topological domainCytoplasmic
HgeneERGIC1chr5:172341841chr5:170720887ENST00000393784+51048_254125291.0Topological domainLumenal
HgeneERGIC1chr5:172351112chr5:170597134ENST00000326654+131_260160.0Topological domainCytoplasmic
HgeneERGIC1chr5:172351112chr5:170597134ENST00000326654+13276_2900160.0Topological domainCytoplasmic
HgeneERGIC1chr5:172351112chr5:170597134ENST00000326654+1348_2540160.0Topological domainLumenal
HgeneERGIC1chr5:172351112chr5:170597134ENST00000393784+610276_290160291.0Topological domainCytoplasmic
HgeneERGIC1chr5:172351112chr5:170597134ENST00000393784+61048_254160291.0Topological domainLumenal
HgeneERGIC1chr5:172341840chr5:170720886ENST00000326654+13255_2750160.0TransmembraneHelical
HgeneERGIC1chr5:172341840chr5:170720886ENST00000326654+1327_470160.0TransmembraneHelical
HgeneERGIC1chr5:172341840chr5:170720886ENST00000393784+510255_275125291.0TransmembraneHelical
HgeneERGIC1chr5:172341841chr5:170720886ENST00000326654+13255_2750160.0TransmembraneHelical
HgeneERGIC1chr5:172341841chr5:170720886ENST00000326654+1327_470160.0TransmembraneHelical
HgeneERGIC1chr5:172341841chr5:170720886ENST00000393784+510255_275125291.0TransmembraneHelical
HgeneERGIC1chr5:172341841chr5:170720887ENST00000326654+13255_2750160.0TransmembraneHelical
HgeneERGIC1chr5:172341841chr5:170720887ENST00000326654+1327_470160.0TransmembraneHelical
HgeneERGIC1chr5:172341841chr5:170720887ENST00000393784+510255_275125291.0TransmembraneHelical
HgeneERGIC1chr5:172351112chr5:170597134ENST00000326654+13255_2750160.0TransmembraneHelical
HgeneERGIC1chr5:172351112chr5:170597134ENST00000326654+1327_470160.0TransmembraneHelical
HgeneERGIC1chr5:172351112chr5:170597134ENST00000393784+610255_275160291.0TransmembraneHelical


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Fusion Gene Sequence for ERGIC1-RANBP17


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>27357_27357_1_ERGIC1-RANBP17_ERGIC1_chr5_172341840_ENST00000393784_RANBP17_chr5_170720886_ENST00000523189_length(transcript)=1995nt_BP=514nt
GGCGAGTGGCGAGTGGCGAGTGTCAGGGGGGCGGCCGGCGGGGGCGGGGCGGCCGGAGGAGGCGTTGGCAGCGGGCTCGGACCCACGCGG
CGCCGCGGCCCGCCTGGCCTGCAGCGCTCCCACCCCCGGCGGCGGCACGATGCCCTTTGACTTCAGGAGGTTTGACATCTACAGGAAGGT
GCCCAAGGACCTTACGCAGCCAACGTACACCGGGGCCATTATCTCCATCTGCTGCTGCCTCTTCATCCTCTTCCTCTTCCTCTCGGAGCT
CACCGGATTTATAACGACAGAAGTTGTGAACGAGCTCTATGTCGATGACCCAGACAAGGACAGCGGTGGCAAGATCGACGTCAGTCTGAA
CATCAGTTTACCCAATCTGCACTGCGAGTTGGTTGGGCTTGACATTCAGGATGAGATGGGCAGGCACGAAGTGGGCCACATCGACAACTC
CATGAAGATCCCGCTGAACAATGGGGCAGGCTGCCGCTTCGAGGGGCAGTTCAGCATCAACAAGATGATGTCTGTCCTCATGAACACCAT
TGTCTTTGAAGACTGTCGGAACCAGTGGTCAGTATCCAGGCCTCTCCTGGGGCTCATCCTGCTCAATGAGAAGTATTTCAGTGAACTGAG
AGCAAGTTTGATAAACAGCCAGCCCCTCCCCAAGCAGGAGGTCCTTGCCCAGTGCTTCAGAAACCTAATGGAAGGAGTGGAGCAGAACCT
GTCCGTCAAGAACAGAGACAGGTTCACCCAAAATCTGTCTGTATTCAGAAGAGATGTGGCAGAGGCGTTGCGCAGTGATGGCAACACTGA
ACCATGCAGTCTCGACATGATGAGCTGACCCGACTTTTCTGACCATGTGCGGAGCAGCCTTTATCAAGAGACTCCTGAAGGTCTGGGTCT
CAGGACAGTGATGTTGGCTAGCCCAGGGGAATGTATTTTTCAAAACATACAAGCAACAGCAAAAGCCCTAACTTCTTATACGTCTAGCCT
AATTATAAGAATTTCTAACAGTACCAGTGTAAATTCAGTCTTTTCTCTGAAAAGCAAAGGATGTGTTTTCAGTCTTTCTATCAAATATTA
TCTTTGTTCTCCTAATGCTCTGAAAGGATGTAGAAACAATATTTAACCAAAGAACGTAATAAACCAGGTTTGCACCTAAGTGTGTACTAG
TTTATGGTTCTGCAGTCAAGGTTGTCAATTTGTTGGAGATGCAGCCTTCACCATGGATCCTGGATTGAGACGAATGCCATTGGAACCTGT
TAAATGAGTAGTTTGTTATGTGTCTGGAAGAAGCAGCGTTAGGGACTTTGGGCTGTGAGCATTTAGAACGAGCCTGGAAGCACTACAGAG
CATCCCACAGGACCACACGCAGGCCTCCCTGCCTCAGCTGCATCTGATAAAGTTGAGAGACAGTAACACAATTAAATGACTTAGAAACAA
TGTTTGCTTTTCACTGGCATAAATCTGAAGTGGTTCAGTCTAGAAGAATTAAGCTGTGCAATTACTGCCTGCAGAGATATTTCTTCAGGA
GGAGTCATGTAGCCCCAGTCAGAAGTTCTGGGTGGTGCCAGCACCCAGTCCTCTGCCTCCATTTAATTTTTAAGAGAAGGTGAAGGTAAC
TATTAGAATATAATATTTGAAGCAGCTCTGCCTTCTTAGGGCTACCCAAAACAGTTCTAGGTGCTAAAATTCAGATTTTCAGAGGATGAG
AAATAGCTGGTTTCCAACTCTCCACAAAAACTCTTATTACTGTTGGGACTTGGGATTCTGACTCACCCCAAACCCAGAACATGAAGAAGA
CCTTTACAGTTTGTGCTCTACTGTTACTAGGCTATTAATTTGAGATCGTCCACTGTCAAGTGTTTTACTATCTCACTGCTGTTTTTATGA
TTCAGGCTTATAACAAATATTGTATCCTTTATTTCTGATAAGACATGAAAGGTTGGCCTTACTGTTGAACAATAAGTAAATCCACAGGCT

>27357_27357_1_ERGIC1-RANBP17_ERGIC1_chr5_172341840_ENST00000393784_RANBP17_chr5_170720886_ENST00000523189_length(amino acids)=257AA_BP=146
MAAGSDPRGAAARLACSAPTPGGGTMPFDFRRFDIYRKVPKDLTQPTYTGAIISICCCLFILFLFLSELTGFITTEVVNELYVDDPDKDS
GGKIDVSLNISLPNLHCELVGLDIQDEMGRHEVGHIDNSMKIPLNNGAGCRFEGQFSINKMMSVLMNTIVFEDCRNQWSVSRPLLGLILL

--------------------------------------------------------------
>27357_27357_2_ERGIC1-RANBP17_ERGIC1_chr5_172341840_ENST00000523291_RANBP17_chr5_170720886_ENST00000523189_length(transcript)=1859nt_BP=378nt
ACGATGCCCTTTGACTTCAGGAGGTTTGACATCTACAGGAAGGTGCCCAAGGACCTTACGCAGCCAACGTACACCGGGGCCATTATCTCC
ATCTGCTGCTGCCTCTTCATCCTCTTCCTCTTCCTCTCGGAGCTCACCGGATTTATAACGACAGAAGTTGTGAACGAGCTCTATGTCGAT
GACCCAGACAAGGACAGCGGTGGCAAGATCGACGTCAGTCTGAACATCAGTTTACCCAATCTGCACTGCGAGTTGGTTGGGCTTGACATT
CAGGATGAGATGGGCAGGCACGAAGTGGGCCACATCGACAACTCCATGAAGATCCCGCTGAACAATGGGGCAGGCTGCCGCTTCGAGGGG
CAGTTCAGCATCAACAAGATGATGTCTGTCCTCATGAACACCATTGTCTTTGAAGACTGTCGGAACCAGTGGTCAGTATCCAGGCCTCTC
CTGGGGCTCATCCTGCTCAATGAGAAGTATTTCAGTGAACTGAGAGCAAGTTTGATAAACAGCCAGCCCCTCCCCAAGCAGGAGGTCCTT
GCCCAGTGCTTCAGAAACCTAATGGAAGGAGTGGAGCAGAACCTGTCCGTCAAGAACAGAGACAGGTTCACCCAAAATCTGTCTGTATTC
AGAAGAGATGTGGCAGAGGCGTTGCGCAGTGATGGCAACACTGAACCATGCAGTCTCGACATGATGAGCTGACCCGACTTTTCTGACCAT
GTGCGGAGCAGCCTTTATCAAGAGACTCCTGAAGGTCTGGGTCTCAGGACAGTGATGTTGGCTAGCCCAGGGGAATGTATTTTTCAAAAC
ATACAAGCAACAGCAAAAGCCCTAACTTCTTATACGTCTAGCCTAATTATAAGAATTTCTAACAGTACCAGTGTAAATTCAGTCTTTTCT
CTGAAAAGCAAAGGATGTGTTTTCAGTCTTTCTATCAAATATTATCTTTGTTCTCCTAATGCTCTGAAAGGATGTAGAAACAATATTTAA
CCAAAGAACGTAATAAACCAGGTTTGCACCTAAGTGTGTACTAGTTTATGGTTCTGCAGTCAAGGTTGTCAATTTGTTGGAGATGCAGCC
TTCACCATGGATCCTGGATTGAGACGAATGCCATTGGAACCTGTTAAATGAGTAGTTTGTTATGTGTCTGGAAGAAGCAGCGTTAGGGAC
TTTGGGCTGTGAGCATTTAGAACGAGCCTGGAAGCACTACAGAGCATCCCACAGGACCACACGCAGGCCTCCCTGCCTCAGCTGCATCTG
ATAAAGTTGAGAGACAGTAACACAATTAAATGACTTAGAAACAATGTTTGCTTTTCACTGGCATAAATCTGAAGTGGTTCAGTCTAGAAG
AATTAAGCTGTGCAATTACTGCCTGCAGAGATATTTCTTCAGGAGGAGTCATGTAGCCCCAGTCAGAAGTTCTGGGTGGTGCCAGCACCC
AGTCCTCTGCCTCCATTTAATTTTTAAGAGAAGGTGAAGGTAACTATTAGAATATAATATTTGAAGCAGCTCTGCCTTCTTAGGGCTACC
CAAAACAGTTCTAGGTGCTAAAATTCAGATTTTCAGAGGATGAGAAATAGCTGGTTTCCAACTCTCCACAAAAACTCTTATTACTGTTGG
GACTTGGGATTCTGACTCACCCCAAACCCAGAACATGAAGAAGACCTTTACAGTTTGTGCTCTACTGTTACTAGGCTATTAATTTGAGAT
CGTCCACTGTCAAGTGTTTTACTATCTCACTGCTGTTTTTATGATTCAGGCTTATAACAAATATTGTATCCTTTATTTCTGATAAGACAT

>27357_27357_2_ERGIC1-RANBP17_ERGIC1_chr5_172341840_ENST00000523291_RANBP17_chr5_170720886_ENST00000523189_length(amino acids)=232AA_BP=121
MPFDFRRFDIYRKVPKDLTQPTYTGAIISICCCLFILFLFLSELTGFITTEVVNELYVDDPDKDSGGKIDVSLNISLPNLHCELVGLDIQ
DEMGRHEVGHIDNSMKIPLNNGAGCRFEGQFSINKMMSVLMNTIVFEDCRNQWSVSRPLLGLILLNEKYFSELRASLINSQPLPKQEVLA

--------------------------------------------------------------
>27357_27357_3_ERGIC1-RANBP17_ERGIC1_chr5_172341841_ENST00000393784_RANBP17_chr5_170720886_ENST00000523189_length(transcript)=1995nt_BP=514nt
GGCGAGTGGCGAGTGGCGAGTGTCAGGGGGGCGGCCGGCGGGGGCGGGGCGGCCGGAGGAGGCGTTGGCAGCGGGCTCGGACCCACGCGG
CGCCGCGGCCCGCCTGGCCTGCAGCGCTCCCACCCCCGGCGGCGGCACGATGCCCTTTGACTTCAGGAGGTTTGACATCTACAGGAAGGT
GCCCAAGGACCTTACGCAGCCAACGTACACCGGGGCCATTATCTCCATCTGCTGCTGCCTCTTCATCCTCTTCCTCTTCCTCTCGGAGCT
CACCGGATTTATAACGACAGAAGTTGTGAACGAGCTCTATGTCGATGACCCAGACAAGGACAGCGGTGGCAAGATCGACGTCAGTCTGAA
CATCAGTTTACCCAATCTGCACTGCGAGTTGGTTGGGCTTGACATTCAGGATGAGATGGGCAGGCACGAAGTGGGCCACATCGACAACTC
CATGAAGATCCCGCTGAACAATGGGGCAGGCTGCCGCTTCGAGGGGCAGTTCAGCATCAACAAGATGATGTCTGTCCTCATGAACACCAT
TGTCTTTGAAGACTGTCGGAACCAGTGGTCAGTATCCAGGCCTCTCCTGGGGCTCATCCTGCTCAATGAGAAGTATTTCAGTGAACTGAG
AGCAAGTTTGATAAACAGCCAGCCCCTCCCCAAGCAGGAGGTCCTTGCCCAGTGCTTCAGAAACCTAATGGAAGGAGTGGAGCAGAACCT
GTCCGTCAAGAACAGAGACAGGTTCACCCAAAATCTGTCTGTATTCAGAAGAGATGTGGCAGAGGCGTTGCGCAGTGATGGCAACACTGA
ACCATGCAGTCTCGACATGATGAGCTGACCCGACTTTTCTGACCATGTGCGGAGCAGCCTTTATCAAGAGACTCCTGAAGGTCTGGGTCT
CAGGACAGTGATGTTGGCTAGCCCAGGGGAATGTATTTTTCAAAACATACAAGCAACAGCAAAAGCCCTAACTTCTTATACGTCTAGCCT
AATTATAAGAATTTCTAACAGTACCAGTGTAAATTCAGTCTTTTCTCTGAAAAGCAAAGGATGTGTTTTCAGTCTTTCTATCAAATATTA
TCTTTGTTCTCCTAATGCTCTGAAAGGATGTAGAAACAATATTTAACCAAAGAACGTAATAAACCAGGTTTGCACCTAAGTGTGTACTAG
TTTATGGTTCTGCAGTCAAGGTTGTCAATTTGTTGGAGATGCAGCCTTCACCATGGATCCTGGATTGAGACGAATGCCATTGGAACCTGT
TAAATGAGTAGTTTGTTATGTGTCTGGAAGAAGCAGCGTTAGGGACTTTGGGCTGTGAGCATTTAGAACGAGCCTGGAAGCACTACAGAG
CATCCCACAGGACCACACGCAGGCCTCCCTGCCTCAGCTGCATCTGATAAAGTTGAGAGACAGTAACACAATTAAATGACTTAGAAACAA
TGTTTGCTTTTCACTGGCATAAATCTGAAGTGGTTCAGTCTAGAAGAATTAAGCTGTGCAATTACTGCCTGCAGAGATATTTCTTCAGGA
GGAGTCATGTAGCCCCAGTCAGAAGTTCTGGGTGGTGCCAGCACCCAGTCCTCTGCCTCCATTTAATTTTTAAGAGAAGGTGAAGGTAAC
TATTAGAATATAATATTTGAAGCAGCTCTGCCTTCTTAGGGCTACCCAAAACAGTTCTAGGTGCTAAAATTCAGATTTTCAGAGGATGAG
AAATAGCTGGTTTCCAACTCTCCACAAAAACTCTTATTACTGTTGGGACTTGGGATTCTGACTCACCCCAAACCCAGAACATGAAGAAGA
CCTTTACAGTTTGTGCTCTACTGTTACTAGGCTATTAATTTGAGATCGTCCACTGTCAAGTGTTTTACTATCTCACTGCTGTTTTTATGA
TTCAGGCTTATAACAAATATTGTATCCTTTATTTCTGATAAGACATGAAAGGTTGGCCTTACTGTTGAACAATAAGTAAATCCACAGGCT

>27357_27357_3_ERGIC1-RANBP17_ERGIC1_chr5_172341841_ENST00000393784_RANBP17_chr5_170720886_ENST00000523189_length(amino acids)=257AA_BP=146
MAAGSDPRGAAARLACSAPTPGGGTMPFDFRRFDIYRKVPKDLTQPTYTGAIISICCCLFILFLFLSELTGFITTEVVNELYVDDPDKDS
GGKIDVSLNISLPNLHCELVGLDIQDEMGRHEVGHIDNSMKIPLNNGAGCRFEGQFSINKMMSVLMNTIVFEDCRNQWSVSRPLLGLILL

--------------------------------------------------------------
>27357_27357_4_ERGIC1-RANBP17_ERGIC1_chr5_172341841_ENST00000393784_RANBP17_chr5_170720887_ENST00000523189_length(transcript)=1995nt_BP=514nt
GGCGAGTGGCGAGTGGCGAGTGTCAGGGGGGCGGCCGGCGGGGGCGGGGCGGCCGGAGGAGGCGTTGGCAGCGGGCTCGGACCCACGCGG
CGCCGCGGCCCGCCTGGCCTGCAGCGCTCCCACCCCCGGCGGCGGCACGATGCCCTTTGACTTCAGGAGGTTTGACATCTACAGGAAGGT
GCCCAAGGACCTTACGCAGCCAACGTACACCGGGGCCATTATCTCCATCTGCTGCTGCCTCTTCATCCTCTTCCTCTTCCTCTCGGAGCT
CACCGGATTTATAACGACAGAAGTTGTGAACGAGCTCTATGTCGATGACCCAGACAAGGACAGCGGTGGCAAGATCGACGTCAGTCTGAA
CATCAGTTTACCCAATCTGCACTGCGAGTTGGTTGGGCTTGACATTCAGGATGAGATGGGCAGGCACGAAGTGGGCCACATCGACAACTC
CATGAAGATCCCGCTGAACAATGGGGCAGGCTGCCGCTTCGAGGGGCAGTTCAGCATCAACAAGATGATGTCTGTCCTCATGAACACCAT
TGTCTTTGAAGACTGTCGGAACCAGTGGTCAGTATCCAGGCCTCTCCTGGGGCTCATCCTGCTCAATGAGAAGTATTTCAGTGAACTGAG
AGCAAGTTTGATAAACAGCCAGCCCCTCCCCAAGCAGGAGGTCCTTGCCCAGTGCTTCAGAAACCTAATGGAAGGAGTGGAGCAGAACCT
GTCCGTCAAGAACAGAGACAGGTTCACCCAAAATCTGTCTGTATTCAGAAGAGATGTGGCAGAGGCGTTGCGCAGTGATGGCAACACTGA
ACCATGCAGTCTCGACATGATGAGCTGACCCGACTTTTCTGACCATGTGCGGAGCAGCCTTTATCAAGAGACTCCTGAAGGTCTGGGTCT
CAGGACAGTGATGTTGGCTAGCCCAGGGGAATGTATTTTTCAAAACATACAAGCAACAGCAAAAGCCCTAACTTCTTATACGTCTAGCCT
AATTATAAGAATTTCTAACAGTACCAGTGTAAATTCAGTCTTTTCTCTGAAAAGCAAAGGATGTGTTTTCAGTCTTTCTATCAAATATTA
TCTTTGTTCTCCTAATGCTCTGAAAGGATGTAGAAACAATATTTAACCAAAGAACGTAATAAACCAGGTTTGCACCTAAGTGTGTACTAG
TTTATGGTTCTGCAGTCAAGGTTGTCAATTTGTTGGAGATGCAGCCTTCACCATGGATCCTGGATTGAGACGAATGCCATTGGAACCTGT
TAAATGAGTAGTTTGTTATGTGTCTGGAAGAAGCAGCGTTAGGGACTTTGGGCTGTGAGCATTTAGAACGAGCCTGGAAGCACTACAGAG
CATCCCACAGGACCACACGCAGGCCTCCCTGCCTCAGCTGCATCTGATAAAGTTGAGAGACAGTAACACAATTAAATGACTTAGAAACAA
TGTTTGCTTTTCACTGGCATAAATCTGAAGTGGTTCAGTCTAGAAGAATTAAGCTGTGCAATTACTGCCTGCAGAGATATTTCTTCAGGA
GGAGTCATGTAGCCCCAGTCAGAAGTTCTGGGTGGTGCCAGCACCCAGTCCTCTGCCTCCATTTAATTTTTAAGAGAAGGTGAAGGTAAC
TATTAGAATATAATATTTGAAGCAGCTCTGCCTTCTTAGGGCTACCCAAAACAGTTCTAGGTGCTAAAATTCAGATTTTCAGAGGATGAG
AAATAGCTGGTTTCCAACTCTCCACAAAAACTCTTATTACTGTTGGGACTTGGGATTCTGACTCACCCCAAACCCAGAACATGAAGAAGA
CCTTTACAGTTTGTGCTCTACTGTTACTAGGCTATTAATTTGAGATCGTCCACTGTCAAGTGTTTTACTATCTCACTGCTGTTTTTATGA
TTCAGGCTTATAACAAATATTGTATCCTTTATTTCTGATAAGACATGAAAGGTTGGCCTTACTGTTGAACAATAAGTAAATCCACAGGCT

>27357_27357_4_ERGIC1-RANBP17_ERGIC1_chr5_172341841_ENST00000393784_RANBP17_chr5_170720887_ENST00000523189_length(amino acids)=257AA_BP=146
MAAGSDPRGAAARLACSAPTPGGGTMPFDFRRFDIYRKVPKDLTQPTYTGAIISICCCLFILFLFLSELTGFITTEVVNELYVDDPDKDS
GGKIDVSLNISLPNLHCELVGLDIQDEMGRHEVGHIDNSMKIPLNNGAGCRFEGQFSINKMMSVLMNTIVFEDCRNQWSVSRPLLGLILL

--------------------------------------------------------------
>27357_27357_5_ERGIC1-RANBP17_ERGIC1_chr5_172341841_ENST00000523291_RANBP17_chr5_170720886_ENST00000523189_length(transcript)=1859nt_BP=378nt
ACGATGCCCTTTGACTTCAGGAGGTTTGACATCTACAGGAAGGTGCCCAAGGACCTTACGCAGCCAACGTACACCGGGGCCATTATCTCC
ATCTGCTGCTGCCTCTTCATCCTCTTCCTCTTCCTCTCGGAGCTCACCGGATTTATAACGACAGAAGTTGTGAACGAGCTCTATGTCGAT
GACCCAGACAAGGACAGCGGTGGCAAGATCGACGTCAGTCTGAACATCAGTTTACCCAATCTGCACTGCGAGTTGGTTGGGCTTGACATT
CAGGATGAGATGGGCAGGCACGAAGTGGGCCACATCGACAACTCCATGAAGATCCCGCTGAACAATGGGGCAGGCTGCCGCTTCGAGGGG
CAGTTCAGCATCAACAAGATGATGTCTGTCCTCATGAACACCATTGTCTTTGAAGACTGTCGGAACCAGTGGTCAGTATCCAGGCCTCTC
CTGGGGCTCATCCTGCTCAATGAGAAGTATTTCAGTGAACTGAGAGCAAGTTTGATAAACAGCCAGCCCCTCCCCAAGCAGGAGGTCCTT
GCCCAGTGCTTCAGAAACCTAATGGAAGGAGTGGAGCAGAACCTGTCCGTCAAGAACAGAGACAGGTTCACCCAAAATCTGTCTGTATTC
AGAAGAGATGTGGCAGAGGCGTTGCGCAGTGATGGCAACACTGAACCATGCAGTCTCGACATGATGAGCTGACCCGACTTTTCTGACCAT
GTGCGGAGCAGCCTTTATCAAGAGACTCCTGAAGGTCTGGGTCTCAGGACAGTGATGTTGGCTAGCCCAGGGGAATGTATTTTTCAAAAC
ATACAAGCAACAGCAAAAGCCCTAACTTCTTATACGTCTAGCCTAATTATAAGAATTTCTAACAGTACCAGTGTAAATTCAGTCTTTTCT
CTGAAAAGCAAAGGATGTGTTTTCAGTCTTTCTATCAAATATTATCTTTGTTCTCCTAATGCTCTGAAAGGATGTAGAAACAATATTTAA
CCAAAGAACGTAATAAACCAGGTTTGCACCTAAGTGTGTACTAGTTTATGGTTCTGCAGTCAAGGTTGTCAATTTGTTGGAGATGCAGCC
TTCACCATGGATCCTGGATTGAGACGAATGCCATTGGAACCTGTTAAATGAGTAGTTTGTTATGTGTCTGGAAGAAGCAGCGTTAGGGAC
TTTGGGCTGTGAGCATTTAGAACGAGCCTGGAAGCACTACAGAGCATCCCACAGGACCACACGCAGGCCTCCCTGCCTCAGCTGCATCTG
ATAAAGTTGAGAGACAGTAACACAATTAAATGACTTAGAAACAATGTTTGCTTTTCACTGGCATAAATCTGAAGTGGTTCAGTCTAGAAG
AATTAAGCTGTGCAATTACTGCCTGCAGAGATATTTCTTCAGGAGGAGTCATGTAGCCCCAGTCAGAAGTTCTGGGTGGTGCCAGCACCC
AGTCCTCTGCCTCCATTTAATTTTTAAGAGAAGGTGAAGGTAACTATTAGAATATAATATTTGAAGCAGCTCTGCCTTCTTAGGGCTACC
CAAAACAGTTCTAGGTGCTAAAATTCAGATTTTCAGAGGATGAGAAATAGCTGGTTTCCAACTCTCCACAAAAACTCTTATTACTGTTGG
GACTTGGGATTCTGACTCACCCCAAACCCAGAACATGAAGAAGACCTTTACAGTTTGTGCTCTACTGTTACTAGGCTATTAATTTGAGAT
CGTCCACTGTCAAGTGTTTTACTATCTCACTGCTGTTTTTATGATTCAGGCTTATAACAAATATTGTATCCTTTATTTCTGATAAGACAT

>27357_27357_5_ERGIC1-RANBP17_ERGIC1_chr5_172341841_ENST00000523291_RANBP17_chr5_170720886_ENST00000523189_length(amino acids)=232AA_BP=121
MPFDFRRFDIYRKVPKDLTQPTYTGAIISICCCLFILFLFLSELTGFITTEVVNELYVDDPDKDSGGKIDVSLNISLPNLHCELVGLDIQ
DEMGRHEVGHIDNSMKIPLNNGAGCRFEGQFSINKMMSVLMNTIVFEDCRNQWSVSRPLLGLILLNEKYFSELRASLINSQPLPKQEVLA

--------------------------------------------------------------
>27357_27357_6_ERGIC1-RANBP17_ERGIC1_chr5_172341841_ENST00000523291_RANBP17_chr5_170720887_ENST00000523189_length(transcript)=1859nt_BP=378nt
ACGATGCCCTTTGACTTCAGGAGGTTTGACATCTACAGGAAGGTGCCCAAGGACCTTACGCAGCCAACGTACACCGGGGCCATTATCTCC
ATCTGCTGCTGCCTCTTCATCCTCTTCCTCTTCCTCTCGGAGCTCACCGGATTTATAACGACAGAAGTTGTGAACGAGCTCTATGTCGAT
GACCCAGACAAGGACAGCGGTGGCAAGATCGACGTCAGTCTGAACATCAGTTTACCCAATCTGCACTGCGAGTTGGTTGGGCTTGACATT
CAGGATGAGATGGGCAGGCACGAAGTGGGCCACATCGACAACTCCATGAAGATCCCGCTGAACAATGGGGCAGGCTGCCGCTTCGAGGGG
CAGTTCAGCATCAACAAGATGATGTCTGTCCTCATGAACACCATTGTCTTTGAAGACTGTCGGAACCAGTGGTCAGTATCCAGGCCTCTC
CTGGGGCTCATCCTGCTCAATGAGAAGTATTTCAGTGAACTGAGAGCAAGTTTGATAAACAGCCAGCCCCTCCCCAAGCAGGAGGTCCTT
GCCCAGTGCTTCAGAAACCTAATGGAAGGAGTGGAGCAGAACCTGTCCGTCAAGAACAGAGACAGGTTCACCCAAAATCTGTCTGTATTC
AGAAGAGATGTGGCAGAGGCGTTGCGCAGTGATGGCAACACTGAACCATGCAGTCTCGACATGATGAGCTGACCCGACTTTTCTGACCAT
GTGCGGAGCAGCCTTTATCAAGAGACTCCTGAAGGTCTGGGTCTCAGGACAGTGATGTTGGCTAGCCCAGGGGAATGTATTTTTCAAAAC
ATACAAGCAACAGCAAAAGCCCTAACTTCTTATACGTCTAGCCTAATTATAAGAATTTCTAACAGTACCAGTGTAAATTCAGTCTTTTCT
CTGAAAAGCAAAGGATGTGTTTTCAGTCTTTCTATCAAATATTATCTTTGTTCTCCTAATGCTCTGAAAGGATGTAGAAACAATATTTAA
CCAAAGAACGTAATAAACCAGGTTTGCACCTAAGTGTGTACTAGTTTATGGTTCTGCAGTCAAGGTTGTCAATTTGTTGGAGATGCAGCC
TTCACCATGGATCCTGGATTGAGACGAATGCCATTGGAACCTGTTAAATGAGTAGTTTGTTATGTGTCTGGAAGAAGCAGCGTTAGGGAC
TTTGGGCTGTGAGCATTTAGAACGAGCCTGGAAGCACTACAGAGCATCCCACAGGACCACACGCAGGCCTCCCTGCCTCAGCTGCATCTG
ATAAAGTTGAGAGACAGTAACACAATTAAATGACTTAGAAACAATGTTTGCTTTTCACTGGCATAAATCTGAAGTGGTTCAGTCTAGAAG
AATTAAGCTGTGCAATTACTGCCTGCAGAGATATTTCTTCAGGAGGAGTCATGTAGCCCCAGTCAGAAGTTCTGGGTGGTGCCAGCACCC
AGTCCTCTGCCTCCATTTAATTTTTAAGAGAAGGTGAAGGTAACTATTAGAATATAATATTTGAAGCAGCTCTGCCTTCTTAGGGCTACC
CAAAACAGTTCTAGGTGCTAAAATTCAGATTTTCAGAGGATGAGAAATAGCTGGTTTCCAACTCTCCACAAAAACTCTTATTACTGTTGG
GACTTGGGATTCTGACTCACCCCAAACCCAGAACATGAAGAAGACCTTTACAGTTTGTGCTCTACTGTTACTAGGCTATTAATTTGAGAT
CGTCCACTGTCAAGTGTTTTACTATCTCACTGCTGTTTTTATGATTCAGGCTTATAACAAATATTGTATCCTTTATTTCTGATAAGACAT

>27357_27357_6_ERGIC1-RANBP17_ERGIC1_chr5_172341841_ENST00000523291_RANBP17_chr5_170720887_ENST00000523189_length(amino acids)=232AA_BP=121
MPFDFRRFDIYRKVPKDLTQPTYTGAIISICCCLFILFLFLSELTGFITTEVVNELYVDDPDKDSGGKIDVSLNISLPNLHCELVGLDIQ
DEMGRHEVGHIDNSMKIPLNNGAGCRFEGQFSINKMMSVLMNTIVFEDCRNQWSVSRPLLGLILLNEKYFSELRASLINSQPLPKQEVLA

--------------------------------------------------------------
>27357_27357_7_ERGIC1-RANBP17_ERGIC1_chr5_172351112_ENST00000393784_RANBP17_chr5_170597134_ENST00000523189_length(transcript)=3333nt_BP=619nt
GGCGAGTGGCGAGTGGCGAGTGTCAGGGGGGCGGCCGGCGGGGGCGGGGCGGCCGGAGGAGGCGTTGGCAGCGGGCTCGGACCCACGCGG
CGCCGCGGCCCGCCTGGCCTGCAGCGCTCCCACCCCCGGCGGCGGCACGATGCCCTTTGACTTCAGGAGGTTTGACATCTACAGGAAGGT
GCCCAAGGACCTTACGCAGCCAACGTACACCGGGGCCATTATCTCCATCTGCTGCTGCCTCTTCATCCTCTTCCTCTTCCTCTCGGAGCT
CACCGGATTTATAACGACAGAAGTTGTGAACGAGCTCTATGTCGATGACCCAGACAAGGACAGCGGTGGCAAGATCGACGTCAGTCTGAA
CATCAGTTTACCCAATCTGCACTGCGAGTTGGTTGGGCTTGACATTCAGGATGAGATGGGCAGGCACGAAGTGGGCCACATCGACAACTC
CATGAAGATCCCGCTGAACAATGGGGCAGGCTGCCGCTTCGAGGGGCAGTTCAGCATCAACAAGGTCCCCGGCAACTTCCACGTGTCCAC
ACACAGTGCCACAGCCCAGCCACAGAACCCAGACATGACGCATGTCATCCACAAGCTCTCCTTTGGGGACACGCTACAGGTATATGCTCG
TATGTCAGAAGTCTTAGGAATAACAGATGACAACCACGTTCTAGAGACGTTCATGACAAAAATTGTTACAAACCTTAAATACTGGGGAAG
ATATGAGCCTGTAATTTCAAGGACTCTTCAGTTCCTAAATGACCTTTCTGTTGGTTATATCCTTTTAAAAAAACTTGTGAAGATAGATGC
TGTGAAATTCATGCTAAAAAACCACACGAGTGAACACTTCCCTTTTCTTGGCATCAGTGACAATCATAGTCTCAGCGACTTCAGGTGTCG
AACAACCTTCTACACAGCGCTCACTCGCCTTCTGATGGTAGATCTGGGTGAAGATGAGGATGAATTTGAGAATTTCATGCTGCCTCTTAC
AGTTGCTTTTGAAACAGTATTACAAATATTCAACAACAACTTTAAACAAGAAGATGTAAAGCGTATGTTGATCGGGCTGGCAAGAGATCT
TCGAGGGATTGCCTTTGCACTGAACACAAAGACCAGCTACACCATGCTGTTTGACTGGATGTACCCAACGTACCTTCCCCTTCTTCAGAA
TGCTGTTGAACGGTGGTATGGAGAGCCAACATGTACAACTCCCATCTTGAAACTTATGGCAGAACTTATGCAAAACAGATCCCAGCGTTT
GAATTTTGATGTATCATCTCCTAATGGAATTCTTCTCTTCAGAGAAGCTAGTAAAATGGTTTGCACTTATGGTAATCAGATCCTGTCCCT
TGGGAGCCTCTCAAAAGATCAGATTTATCCAATGAAACTCAAGGGCATCTCCATCTGCTATTCAGCTCTCAAGTCTGCCTTGTGTGGAAA
TTATGTCAGCTTTGGCGTCTTCAAGTTGTATGGGGACAACCATTTTGACAATGTACTCCAGGCTTTTGTCAAAATGCTGCTGTCAGTGTC
CCACAGTGACTTGCTACAATACCGGAAACTGAGCCAGTCTTATTATCCACTCCTGGAATGTCTCACTCAGGACCATATGAGCTTCATCAT
CAACTTAGAGCCTCCTGTACTCATGTATGTTCTCACATCTATCTCAGAGGGACTCACTACTCTTGATACAGTTGTCTCCTCCAGCTGCTG
TACCAGTTTAGACTACATCGTCACCTACCTCTTCAAGCACATAGCAAAAGAGGGCAAGAAGCCACTTCGATGCAGAGAGGCTACCCAGGC
TGGTCAGAGACTATTACATTTTATGCAGCAAAACCCAGATGTCCTGCAGCAGATGATGTCTGTCCTCATGAACACCATTGTCTTTGAAGA
CTGTCGGAACCAGTGGTCAGTATCCAGGCCTCTCCTGGGGCTCATCCTGCTCAATGAGAAGTATTTCAGTGAACTGAGAGCAAGTTTGAT
AAACAGCCAGCCCCTCCCCAAGCAGGAGGTCCTTGCCCAGTGCTTCAGAAACCTAATGGAAGGAGTGGAGCAGAACCTGTCCGTCAAGAA
CAGAGACAGGTTCACCCAAAATCTGTCTGTATTCAGAAGAGATGTGGCAGAGGCGTTGCGCAGTGATGGCAACACTGAACCATGCAGTCT
CGACATGATGAGCTGACCCGACTTTTCTGACCATGTGCGGAGCAGCCTTTATCAAGAGACTCCTGAAGGTCTGGGTCTCAGGACAGTGAT
GTTGGCTAGCCCAGGGGAATGTATTTTTCAAAACATACAAGCAACAGCAAAAGCCCTAACTTCTTATACGTCTAGCCTAATTATAAGAAT
TTCTAACAGTACCAGTGTAAATTCAGTCTTTTCTCTGAAAAGCAAAGGATGTGTTTTCAGTCTTTCTATCAAATATTATCTTTGTTCTCC
TAATGCTCTGAAAGGATGTAGAAACAATATTTAACCAAAGAACGTAATAAACCAGGTTTGCACCTAAGTGTGTACTAGTTTATGGTTCTG
CAGTCAAGGTTGTCAATTTGTTGGAGATGCAGCCTTCACCATGGATCCTGGATTGAGACGAATGCCATTGGAACCTGTTAAATGAGTAGT
TTGTTATGTGTCTGGAAGAAGCAGCGTTAGGGACTTTGGGCTGTGAGCATTTAGAACGAGCCTGGAAGCACTACAGAGCATCCCACAGGA
CCACACGCAGGCCTCCCTGCCTCAGCTGCATCTGATAAAGTTGAGAGACAGTAACACAATTAAATGACTTAGAAACAATGTTTGCTTTTC
ACTGGCATAAATCTGAAGTGGTTCAGTCTAGAAGAATTAAGCTGTGCAATTACTGCCTGCAGAGATATTTCTTCAGGAGGAGTCATGTAG
CCCCAGTCAGAAGTTCTGGGTGGTGCCAGCACCCAGTCCTCTGCCTCCATTTAATTTTTAAGAGAAGGTGAAGGTAACTATTAGAATATA
ATATTTGAAGCAGCTCTGCCTTCTTAGGGCTACCCAAAACAGTTCTAGGTGCTAAAATTCAGATTTTCAGAGGATGAGAAATAGCTGGTT
TCCAACTCTCCACAAAAACTCTTATTACTGTTGGGACTTGGGATTCTGACTCACCCCAAACCCAGAACATGAAGAAGACCTTTACAGTTT
GTGCTCTACTGTTACTAGGCTATTAATTTGAGATCGTCCACTGTCAAGTGTTTTACTATCTCACTGCTGTTTTTATGATTCAGGCTTATA
ACAAATATTGTATCCTTTATTTCTGATAAGACATGAAAGGTTGGCCTTACTGTTGAACAATAAGTAAATCCACAGGCTCCTGTTGTAATC

>27357_27357_7_ERGIC1-RANBP17_ERGIC1_chr5_172351112_ENST00000393784_RANBP17_chr5_170597134_ENST00000523189_length(amino acids)=703AA_BP=184
MAAGSDPRGAAARLACSAPTPGGGTMPFDFRRFDIYRKVPKDLTQPTYTGAIISICCCLFILFLFLSELTGFITTEVVNELYVDDPDKDS
GGKIDVSLNISLPNLHCELVGLDIQDEMGRHEVGHIDNSMKIPLNNGAGCRFEGQFSINKVPGNFHVSTHSATAQPQNPDMTHVIHKLSF
GDTLQVYARMSEVLGITDDNHVLETFMTKIVTNLKYWGRYEPVISRTLQFLNDLSVGYILLKKLVKIDAVKFMLKNHTSEHFPFLGISDN
HSLSDFRCRTTFYTALTRLLMVDLGEDEDEFENFMLPLTVAFETVLQIFNNNFKQEDVKRMLIGLARDLRGIAFALNTKTSYTMLFDWMY
PTYLPLLQNAVERWYGEPTCTTPILKLMAELMQNRSQRLNFDVSSPNGILLFREASKMVCTYGNQILSLGSLSKDQIYPMKLKGISICYS
ALKSALCGNYVSFGVFKLYGDNHFDNVLQAFVKMLLSVSHSDLLQYRKLSQSYYPLLECLTQDHMSFIINLEPPVLMYVLTSISEGLTTL
DTVVSSSCCTSLDYIVTYLFKHIAKEGKKPLRCREATQAGQRLLHFMQQNPDVLQQMMSVLMNTIVFEDCRNQWSVSRPLLGLILLNEKY

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Fusion Gene PPI Analysis for ERGIC1-RANBP17


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ERGIC1-RANBP17


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ERGIC1-RANBP17


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneERGIC1C1859721ARTHROGRYPOSIS MULTIPLEX CONGENITA, NEUROGENIC TYPE (disorder)1CTD_human;ORPHANET;UNIPROT