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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:BIRC6-TTC27 (FusionGDB2 ID:HG57448TG55622)

Fusion Gene Summary for BIRC6-TTC27

check button Fusion gene summary
Fusion gene informationFusion gene name: BIRC6-TTC27
Fusion gene ID: hg57448tg55622
HgeneTgene
Gene symbol

BIRC6

TTC27

Gene ID

57448

55622

Gene namebaculoviral IAP repeat containing 6tetratricopeptide repeat domain 27
SynonymsAPOLLON|BRUCE-
Cytomap('BIRC6')('TTC27')

2p22.3

2p22.3

Type of geneprotein-codingprotein-coding
Descriptionbaculoviral IAP repeat-containing protein 6BIR repeat-containing ubiquitin-conjugating enzymeRING-type E3 ubiquitin transferase BIRC6ubiquitin-conjugating BIR-domain enzyme apollontetratricopeptide repeat protein 27TPR repeat protein 27
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000421745, ENST00000421745, 
Fusion gene scores* DoF score21 X 23 X 16=772811 X 15 X 8=1320
# samples 3320
** MAII scorelog2(33/7728*10)=-4.54955716458996
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(20/1320*10)=-2.72246602447109
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: BIRC6 [Title/Abstract] AND TTC27 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointBIRC6(32695369)-TTC27(33002948), # samples:2
BIRC6(32582554)-TTC27(33042524), # samples:2
Anticipated loss of major functional domain due to fusion event.BIRC6-TTC27 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
BIRC6-TTC27 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
BIRC6-TTC27 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
BIRC6-TTC27 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
TTC27-BIRC6 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
TTC27-BIRC6 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
BIRC6-TTC27 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
BIRC6-TTC27 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
BIRC6-TTC27 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across BIRC6 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across TTC27 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ACCTCGA-OR-A5JC-01ABIRC6chr2

32582554

+TTC27chr2

33042524

+
ChimerDB4ACCTCGA-OR-A5JCBIRC6chr2

32582554

+TTC27chr2

33042523

+
ChimerDB4BRCATCGA-AR-A256-01ABIRC6chr2

32774548

+TTC27chr2

33007693

+
ChimerDB4BRCATCGA-BH-A18J-01ABIRC6chr2

32605358

+TTC27chr2

32897339

+
ChimerDB4ESCATCGA-2H-A9GHBIRC6chr2

32774548

+TTC27chr2

32958895

+
ChimerDB4ESCATCGA-LN-A49UBIRC6chr2

32695369

+TTC27chr2

33002948

+
ChimerDB4ESCATCGA-LN-A49UBIRC6chr2

32695369

+TTC27chr2

33002949

+
ChimerDB4OVTCGA-09-2054-01ABIRC6chr2

32704685

+TTC27chr2

33002949

+
ChimerDB4STADTCGA-D7-A4YU-01ABIRC6chr2

32768608

+TTC27chr2

32891702

+
ChimerDB4STADTCGA-D7-A4YUBIRC6chr2

32768608

+TTC27chr2

32891701

+
ChimerDB4UCSTCGA-N9-A4Q4BIRC6chr2

32582554

+TTC27chr2

33042524

+


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Fusion Gene ORF analysis for BIRC6-TTC27

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000421745ENST00000317907BIRC6chr2

32774548

+TTC27chr2

33007693

+
Frame-shiftENST00000421745ENST00000317907BIRC6chr2

32774548

+TTC27chr2

32958895

+
Frame-shiftENST00000421745ENST00000317907BIRC6chr2

32695369

+TTC27chr2

33002948

+
Frame-shiftENST00000421745ENST00000317907BIRC6chr2

32695369

+TTC27chr2

33002949

+
Frame-shiftENST00000421745ENST00000317907BIRC6chr2

32704685

+TTC27chr2

33002949

+
In-frameENST00000421745ENST00000317907BIRC6chr2

32582554

+TTC27chr2

33042524

+
In-frameENST00000421745ENST00000317907BIRC6chr2

32582554

+TTC27chr2

33042523

+
In-frameENST00000421745ENST00000317907BIRC6chr2

32605358

+TTC27chr2

32897339

+
In-frameENST00000421745ENST00000317907BIRC6chr2

32768608

+TTC27chr2

32891702

+
In-frameENST00000421745ENST00000317907BIRC6chr2

32768608

+TTC27chr2

32891701

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000421745BIRC6chr232582554+ENST00000317907TTC27chr233042523+796459134682182
ENST00000421745BIRC6chr232768608+ENST00000317907TTC27chr232891701+1456612726134144524772
ENST00000421745BIRC6chr232582554+ENST00000317907TTC27chr233042524+796459134682182
ENST00000421745BIRC6chr232605358+ENST00000317907TTC27chr232897339+24857791342371745
ENST00000421745BIRC6chr232768608+ENST00000317907TTC27chr232891702+1456612726134144524772

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000421745ENST00000317907BIRC6chr232582554+TTC27chr233042523+0.0115632290.98843676
ENST00000421745ENST00000317907BIRC6chr232768608+TTC27chr232891701+0.0008138730.9991861
ENST00000421745ENST00000317907BIRC6chr232582554+TTC27chr233042524+0.0115632290.98843676
ENST00000421745ENST00000317907BIRC6chr232605358+TTC27chr232897339+0.0011753480.99882466
ENST00000421745ENST00000317907BIRC6chr232768608+TTC27chr232891702+0.0008138730.9991861

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Fusion Genomic Features for BIRC6-TTC27


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
BIRC6chr232695369+TTC27chr233002948+0.0005380160.99946195
BIRC6chr232704685+TTC27chr233002948+2.16E-050.9999784
BIRC6chr232774548+TTC27chr233007692+9.63E-060.99999034
BIRC6chr232774548+TTC27chr232958894+2.49E-070.99999976
BIRC6chr232768608+TTC27chr232891701+8.48E-080.9999999
BIRC6chr232768608+TTC27chr232891701+8.48E-080.9999999
BIRC6chr232582554+TTC27chr233042523+3.56E-101
BIRC6chr232582554+TTC27chr233042523+3.56E-101
BIRC6chr232605358+TTC27chr232897338+3.90E-111
BIRC6chr232582554+TTC27chr233042523+3.56E-101
BIRC6chr232695369+TTC27chr233002948+0.0005380160.99946195
BIRC6chr232704685+TTC27chr233002948+2.16E-050.9999784
BIRC6chr232774548+TTC27chr233007692+9.63E-060.99999034
BIRC6chr232774548+TTC27chr232958894+2.49E-070.99999976
BIRC6chr232768608+TTC27chr232891701+8.48E-080.9999999
BIRC6chr232768608+TTC27chr232891701+8.48E-080.9999999
BIRC6chr232582554+TTC27chr233042523+3.56E-101
BIRC6chr232582554+TTC27chr233042523+3.56E-101
BIRC6chr232605358+TTC27chr232897338+3.90E-111
BIRC6chr232582554+TTC27chr233042523+3.56E-101

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for BIRC6-TTC27


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:32695369/chr2:33002948)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBIRC6chr2:32582554chr2:33042523ENST00000421745+17430_361084858.0Compositional biasNote=Poly-Ala
HgeneBIRC6chr2:32582554chr2:33042524ENST00000421745+17430_361084858.0Compositional biasNote=Poly-Ala
HgeneBIRC6chr2:32605358chr2:32897339ENST00000421745+37430_362154858.0Compositional biasNote=Poly-Ala
HgeneBIRC6chr2:32768608chr2:32891701ENST00000421745+62741660_166841974858.0Compositional biasNote=Poly-Ala
HgeneBIRC6chr2:32768608chr2:32891701ENST00000421745+627430_3641974858.0Compositional biasNote=Poly-Ala
HgeneBIRC6chr2:32768608chr2:32891702ENST00000421745+62741660_166841974858.0Compositional biasNote=Poly-Ala
HgeneBIRC6chr2:32768608chr2:32891702ENST00000421745+627430_3641974858.0Compositional biasNote=Poly-Ala
HgeneBIRC6chr2:32768608chr2:32891701ENST00000421745+6274284_35841974858.0RepeatNote=BIR
HgeneBIRC6chr2:32768608chr2:32891702ENST00000421745+6274284_35841974858.0RepeatNote=BIR
TgeneTTC27chr2:32605358chr2:32897339ENST00000317907620453_486313844.0RepeatNote=TPR 1
TgeneTTC27chr2:32605358chr2:32897339ENST00000317907620492_525313844.0RepeatNote=TPR 2
TgeneTTC27chr2:32605358chr2:32897339ENST00000317907620527_560313844.0RepeatNote=TPR 3
TgeneTTC27chr2:32605358chr2:32897339ENST00000317907620561_594313844.0RepeatNote=TPR 4
TgeneTTC27chr2:32605358chr2:32897339ENST00000317907620596_628313844.0RepeatNote=TPR 5
TgeneTTC27chr2:32605358chr2:32897339ENST00000317907620629_662313844.0RepeatNote=TPR 6
TgeneTTC27chr2:32768608chr2:32891701ENST00000317907520453_486268844.0RepeatNote=TPR 1
TgeneTTC27chr2:32768608chr2:32891701ENST00000317907520492_525268844.0RepeatNote=TPR 2
TgeneTTC27chr2:32768608chr2:32891701ENST00000317907520527_560268844.0RepeatNote=TPR 3
TgeneTTC27chr2:32768608chr2:32891701ENST00000317907520561_594268844.0RepeatNote=TPR 4
TgeneTTC27chr2:32768608chr2:32891701ENST00000317907520596_628268844.0RepeatNote=TPR 5
TgeneTTC27chr2:32768608chr2:32891701ENST00000317907520629_662268844.0RepeatNote=TPR 6
TgeneTTC27chr2:32768608chr2:32891702ENST00000317907520453_486268844.0RepeatNote=TPR 1
TgeneTTC27chr2:32768608chr2:32891702ENST00000317907520492_525268844.0RepeatNote=TPR 2
TgeneTTC27chr2:32768608chr2:32891702ENST00000317907520527_560268844.0RepeatNote=TPR 3
TgeneTTC27chr2:32768608chr2:32891702ENST00000317907520561_594268844.0RepeatNote=TPR 4
TgeneTTC27chr2:32768608chr2:32891702ENST00000317907520596_628268844.0RepeatNote=TPR 5
TgeneTTC27chr2:32768608chr2:32891702ENST00000317907520629_662268844.0RepeatNote=TPR 6

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBIRC6chr2:32582554chr2:33042523ENST00000421745+1741660_16681084858.0Compositional biasNote=Poly-Ala
HgeneBIRC6chr2:32582554chr2:33042524ENST00000421745+1741660_16681084858.0Compositional biasNote=Poly-Ala
HgeneBIRC6chr2:32605358chr2:32897339ENST00000421745+3741660_16682154858.0Compositional biasNote=Poly-Ala
HgeneBIRC6chr2:32582554chr2:33042523ENST00000421745+1744573_47401084858.0DomainUBC core
HgeneBIRC6chr2:32582554chr2:33042524ENST00000421745+1744573_47401084858.0DomainUBC core
HgeneBIRC6chr2:32605358chr2:32897339ENST00000421745+3744573_47402154858.0DomainUBC core
HgeneBIRC6chr2:32768608chr2:32891701ENST00000421745+62744573_474041974858.0DomainUBC core
HgeneBIRC6chr2:32768608chr2:32891702ENST00000421745+62744573_474041974858.0DomainUBC core
HgeneBIRC6chr2:32582554chr2:33042523ENST00000421745+174284_3581084858.0RepeatNote=BIR
HgeneBIRC6chr2:32582554chr2:33042524ENST00000421745+174284_3581084858.0RepeatNote=BIR
HgeneBIRC6chr2:32605358chr2:32897339ENST00000421745+374284_3582154858.0RepeatNote=BIR
TgeneTTC27chr2:32582554chr2:33042523ENST000003179071720453_486769844.0RepeatNote=TPR 1
TgeneTTC27chr2:32582554chr2:33042523ENST000003179071720492_525769844.0RepeatNote=TPR 2
TgeneTTC27chr2:32582554chr2:33042523ENST000003179071720527_560769844.0RepeatNote=TPR 3
TgeneTTC27chr2:32582554chr2:33042523ENST000003179071720561_594769844.0RepeatNote=TPR 4
TgeneTTC27chr2:32582554chr2:33042523ENST000003179071720596_628769844.0RepeatNote=TPR 5
TgeneTTC27chr2:32582554chr2:33042523ENST000003179071720629_662769844.0RepeatNote=TPR 6
TgeneTTC27chr2:32582554chr2:33042524ENST000003179071720453_486769844.0RepeatNote=TPR 1
TgeneTTC27chr2:32582554chr2:33042524ENST000003179071720492_525769844.0RepeatNote=TPR 2
TgeneTTC27chr2:32582554chr2:33042524ENST000003179071720527_560769844.0RepeatNote=TPR 3
TgeneTTC27chr2:32582554chr2:33042524ENST000003179071720561_594769844.0RepeatNote=TPR 4
TgeneTTC27chr2:32582554chr2:33042524ENST000003179071720596_628769844.0RepeatNote=TPR 5
TgeneTTC27chr2:32582554chr2:33042524ENST000003179071720629_662769844.0RepeatNote=TPR 6


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Fusion Gene Sequence for BIRC6-TTC27


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>9769_9769_1_BIRC6-TTC27_BIRC6_chr2_32582554_ENST00000421745_TTC27_chr2_33042523_ENST00000317907_length(transcript)=796nt_BP=459nt
TCCCTGCTTCTCCCCCTCTCCCGTCAGCCTCCCTCCGAGTTTGGCCCCTCCGGCCGGGCGATCGACGTTCCGCGTGCGTGCGGGCGCCTG
ACTTCACTTCCGGCTAACGCGCTCGGCTTGCCCCCTGGCCCCGGATGGTGACTGGTGGTGGTGCTGCACCTCCCGGGACTGTCACTGAGC
CGCTTCCCAGTGTGATTGTGCTGAGCGCAGGCCGGAAGATGGCGGCTGCGGCTGCGGCGGCCTCGGGCCCCGGCTGCTCCTCGGCGGCGG
GGGCGGGGGCGGCCGGGGTCTCAGAGTGGCTGGTGCTGCGGGACGGCTGCATGCACTGCGACGCCGACGGGCTGCACAGCCTGTCCTACC
ACCCTGCGCTCAACGCCATCCTGGCCGTCACTAGCCGCGGGACCATCAAAGTCATCGACGGCACCTCGGGGGCCACACTGCAGGCCTCCG
CGCTCAGTGTGGCCATAAAATGCAGTAAAAACAAATCCAGTTCCCAAGAAGCTGTACAAATGCTTTCTTCTGTTCGACTCAATTTACGGG
GCTTGTTATCTAAAGCAAAGCAACTTTTTACAGATGTGGCAACTGGAGAAATGTCCAGGGAATTAGCTGATGACATAACAGCTATGGACA
CCTTAGTGACAGAGCTCCAAGACCTAAGCAACCAGTTTCGAAATCAGTATTGATTCTGCTGGAAGCAGATTCTGGAAAAGGTGCTTTCAC

>9769_9769_1_BIRC6-TTC27_BIRC6_chr2_32582554_ENST00000421745_TTC27_chr2_33042523_ENST00000317907_length(amino acids)=182AA_BP=0
MVTGGGAAPPGTVTEPLPSVIVLSAGRKMAAAAAAASGPGCSSAAGAGAAGVSEWLVLRDGCMHCDADGLHSLSYHPALNAILAVTSRGT
IKVIDGTSGATLQASALSVAIKCSKNKSSSQEAVQMLSSVRLNLRGLLSKAKQLFTDVATGEMSRELADDITAMDTLVTELQDLSNQFRN

--------------------------------------------------------------
>9769_9769_2_BIRC6-TTC27_BIRC6_chr2_32582554_ENST00000421745_TTC27_chr2_33042524_ENST00000317907_length(transcript)=796nt_BP=459nt
TCCCTGCTTCTCCCCCTCTCCCGTCAGCCTCCCTCCGAGTTTGGCCCCTCCGGCCGGGCGATCGACGTTCCGCGTGCGTGCGGGCGCCTG
ACTTCACTTCCGGCTAACGCGCTCGGCTTGCCCCCTGGCCCCGGATGGTGACTGGTGGTGGTGCTGCACCTCCCGGGACTGTCACTGAGC
CGCTTCCCAGTGTGATTGTGCTGAGCGCAGGCCGGAAGATGGCGGCTGCGGCTGCGGCGGCCTCGGGCCCCGGCTGCTCCTCGGCGGCGG
GGGCGGGGGCGGCCGGGGTCTCAGAGTGGCTGGTGCTGCGGGACGGCTGCATGCACTGCGACGCCGACGGGCTGCACAGCCTGTCCTACC
ACCCTGCGCTCAACGCCATCCTGGCCGTCACTAGCCGCGGGACCATCAAAGTCATCGACGGCACCTCGGGGGCCACACTGCAGGCCTCCG
CGCTCAGTGTGGCCATAAAATGCAGTAAAAACAAATCCAGTTCCCAAGAAGCTGTACAAATGCTTTCTTCTGTTCGACTCAATTTACGGG
GCTTGTTATCTAAAGCAAAGCAACTTTTTACAGATGTGGCAACTGGAGAAATGTCCAGGGAATTAGCTGATGACATAACAGCTATGGACA
CCTTAGTGACAGAGCTCCAAGACCTAAGCAACCAGTTTCGAAATCAGTATTGATTCTGCTGGAAGCAGATTCTGGAAAAGGTGCTTTCAC

>9769_9769_2_BIRC6-TTC27_BIRC6_chr2_32582554_ENST00000421745_TTC27_chr2_33042524_ENST00000317907_length(amino acids)=182AA_BP=0
MVTGGGAAPPGTVTEPLPSVIVLSAGRKMAAAAAAASGPGCSSAAGAGAAGVSEWLVLRDGCMHCDADGLHSLSYHPALNAILAVTSRGT
IKVIDGTSGATLQASALSVAIKCSKNKSSSQEAVQMLSSVRLNLRGLLSKAKQLFTDVATGEMSRELADDITAMDTLVTELQDLSNQFRN

--------------------------------------------------------------
>9769_9769_3_BIRC6-TTC27_BIRC6_chr2_32605358_ENST00000421745_TTC27_chr2_32897339_ENST00000317907_length(transcript)=2485nt_BP=779nt
TCCCTGCTTCTCCCCCTCTCCCGTCAGCCTCCCTCCGAGTTTGGCCCCTCCGGCCGGGCGATCGACGTTCCGCGTGCGTGCGGGCGCCTG
ACTTCACTTCCGGCTAACGCGCTCGGCTTGCCCCCTGGCCCCGGATGGTGACTGGTGGTGGTGCTGCACCTCCCGGGACTGTCACTGAGC
CGCTTCCCAGTGTGATTGTGCTGAGCGCAGGCCGGAAGATGGCGGCTGCGGCTGCGGCGGCCTCGGGCCCCGGCTGCTCCTCGGCGGCGG
GGGCGGGGGCGGCCGGGGTCTCAGAGTGGCTGGTGCTGCGGGACGGCTGCATGCACTGCGACGCCGACGGGCTGCACAGCCTGTCCTACC
ACCCTGCGCTCAACGCCATCCTGGCCGTCACTAGCCGCGGGACCATCAAAGTCATCGACGGCACCTCGGGGGCCACACTGCAGGCCTCCG
CGCTCAGTGCTAAACCAGGTGGACAGGTGAAATGTCAGTATATCTCTGCTGTGGATAAAGTTATATTTGTGGATGATTATGCAGTAGGGT
GTAGGAAGGACCTTAATGGAATCTTGTTGTTAGACACTGCTCTGCAAACTCCAGTTTCAAAGCAGGATGATGTGGTTCAGCTTGAATTAC
CCGTTACAGAGGCACAGCAGCTCTTATCAGCATGTTTAGAAAAGGTAGATATTTCTAGTACAGAGGGTTATGATTTGTTCATCACACAGC
TCAAAGATGGTTTAAAAAATACATCTCATGAGACTGCAGCAAACCACAAAGTTGCTAAGAATCTTGAGCTCAATGATGACACCATTCTGA
ATGACATAAAGTTAGCAGATTGTGAACAGTTCCAGATGCCGGATCTGTGTGCTGAAGAGATCGCTATTATTCTTGGAATCTGCACTAATT
TTCAAAAGAATAACCCAGTGCACACATTAACTGAAGTGGAGCTTCTGGCATTTACATCATGTTTGCTTTCACAACCAAAGTTCTGGGCCA
TTCAGACATCAGCCTTGATCCTCCGGACAAAACTTGAGAAAGGAAGTACTCGCCGAGTGGAACGGGCAATGAGGCAGACACAGGCTCTTG
CAGACCAATTTGAAGATAAAACTACATCTGTATTGGAACGCCTGAAGATTTTCTATTGCTGTCAAGTACCACCTCACTGGGCCATTCAGC
GCCAACTTGCAAGTTTGCTCTTTGAGTTGGGATGTACCAGTTCAGCCCTTCAGATATTTGAAAAGCTAGAAATGTGGGAAGATGTTGTCA
TTTGTTATGAAAGAGCCGGGCAGCACGGAAAGGCAGAAGAAATCCTTAGACAAGAGCTGGAGAAAAAAGAAACGCCTAGTTTATACTGCT
TGCTTGGAGATGTCCTCGGAGACCATTCTTGCTATGACAAGGCCTGGGAGTTGTCCCGGTACCGCAGTGCTCGTGCTCAGCGCTCCAAAG
CCCTCCTTCATCTTCGGAACAAGGAGTTTCAAGAGTGTGTAGAGTGCTTCGAACGCTCGGTTAAGATTAATCCCATGCAGCTCGGGGTGT
GGTTTTCTCTCGGTTGTGCCTATTTGGCCTTGGAAGACTATCAAGGTTCAGCAAAGGCATTTCAGCGCTGTGTGACTCTAGAACCCGATA
ATGCTGAAGCTTGGAACAATTTGTCAACTTCCTATATCCGATTAAAACAAAAAGTAAAAGCTTTTAGAACTTTACAAGAAGCTCTCAAGT
GTAACTATGAACACTGGCAGATTTGGGAAAACTACATCCTCACCAGCACTGACGTTGGGGAATTTTCAGAAGCCATTAAAGCTTATCACC
GGCTCTTGGACTTACGTGACAAATACAAAGATGTTCAGGTCCTTAAAATTCTAGTCAGGGCAGTGATTGATGGGATGACTGATCGAAGTG
GAGATGTTGCAACTGGCCTCAAAGGAAAGCTGCAGGAGTTATTTGGCAGAGTGACTTCAAGAGTGACAAATGATGGAGAAATCTGGAGGC
TGTATGCCCACGTATATGGAAATGGGCAGAGTGAAAAGCCTGATGAAAATGAAAAGGCATTCCAGTGCCTCTCAAAGGCATACAAGTGTG
ACACCCAGTCCAATTGTTGGGAGAAAGATATTACATCATTTAAGGAAGTTGTTCAAAGAGCCTTAGGACTTGCACATGTGGCCATAAAAT
GCAGTAAAAACAAATCCAGTTCCCAAGAAGCTGTACAAATGCTTTCTTCTGTTCGACTCAATTTACGGGGCTTGTTATCTAAAGCAAAGC
AACTTTTTACAGATGTGGCAACTGGAGAAATGTCCAGGGAATTAGCTGATGACATAACAGCTATGGACACCTTAGTGACAGAGCTCCAAG
ACCTAAGCAACCAGTTTCGAAATCAGTATTGATTCTGCTGGAAGCAGATTCTGGAAAAGGTGCTTTCACCTGCTGGTAAAAGATACATCT

>9769_9769_3_BIRC6-TTC27_BIRC6_chr2_32605358_ENST00000421745_TTC27_chr2_32897339_ENST00000317907_length(amino acids)=745AA_BP=0
MVTGGGAAPPGTVTEPLPSVIVLSAGRKMAAAAAAASGPGCSSAAGAGAAGVSEWLVLRDGCMHCDADGLHSLSYHPALNAILAVTSRGT
IKVIDGTSGATLQASALSAKPGGQVKCQYISAVDKVIFVDDYAVGCRKDLNGILLLDTALQTPVSKQDDVVQLELPVTEAQQLLSACLEK
VDISSTEGYDLFITQLKDGLKNTSHETAANHKVAKNLELNDDTILNDIKLADCEQFQMPDLCAEEIAIILGICTNFQKNNPVHTLTEVEL
LAFTSCLLSQPKFWAIQTSALILRTKLEKGSTRRVERAMRQTQALADQFEDKTTSVLERLKIFYCCQVPPHWAIQRQLASLLFELGCTSS
ALQIFEKLEMWEDVVICYERAGQHGKAEEILRQELEKKETPSLYCLLGDVLGDHSCYDKAWELSRYRSARAQRSKALLHLRNKEFQECVE
CFERSVKINPMQLGVWFSLGCAYLALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILT
STDVGEFSEAIKAYHRLLDLRDKYKDVQVLKILVRAVIDGMTDRSGDVATGLKGKLQELFGRVTSRVTNDGEIWRLYAHVYGNGQSEKPD
ENEKAFQCLSKAYKCDTQSNCWEKDITSFKEVVQRALGLAHVAIKCSKNKSSSQEAVQMLSSVRLNLRGLLSKAKQLFTDVATGEMSREL

--------------------------------------------------------------
>9769_9769_4_BIRC6-TTC27_BIRC6_chr2_32768608_ENST00000421745_TTC27_chr2_32891701_ENST00000317907_length(transcript)=14566nt_BP=12726nt
TCCCTGCTTCTCCCCCTCTCCCGTCAGCCTCCCTCCGAGTTTGGCCCCTCCGGCCGGGCGATCGACGTTCCGCGTGCGTGCGGGCGCCTG
ACTTCACTTCCGGCTAACGCGCTCGGCTTGCCCCCTGGCCCCGGATGGTGACTGGTGGTGGTGCTGCACCTCCCGGGACTGTCACTGAGC
CGCTTCCCAGTGTGATTGTGCTGAGCGCAGGCCGGAAGATGGCGGCTGCGGCTGCGGCGGCCTCGGGCCCCGGCTGCTCCTCGGCGGCGG
GGGCGGGGGCGGCCGGGGTCTCAGAGTGGCTGGTGCTGCGGGACGGCTGCATGCACTGCGACGCCGACGGGCTGCACAGCCTGTCCTACC
ACCCTGCGCTCAACGCCATCCTGGCCGTCACTAGCCGCGGGACCATCAAAGTCATCGACGGCACCTCGGGGGCCACACTGCAGGCCTCCG
CGCTCAGTGCTAAACCAGGTGGACAGGTGAAATGTCAGTATATCTCTGCTGTGGATAAAGTTATATTTGTGGATGATTATGCAGTAGGGT
GTAGGAAGGACCTTAATGGAATCTTGTTGTTAGACACTGCTCTGCAAACTCCAGTTTCAAAGCAGGATGATGTGGTTCAGCTTGAATTAC
CCGTTACAGAGGCACAGCAGCTCTTATCAGCATGTTTAGAAAAGGTAGATATTTCTAGTACAGAGGGTTATGATTTGTTCATCACACAGC
TCAAAGATGGTTTAAAAAATACATCTCATGAGACTGCAGCAAACCACAAAGTTGCTAAGTGGGCCACAGTTACATTTCATCTTCCTCATC
ATGTGTTGAAGTCCATTGCCAGTGCCATTGTAAATGAACTCAAGAAAATAAATCAAAATGTTGCTGCCTTACCTGTGGCGTCCTCAGTGA
TGGACAGATTGTCTTACCTCTTACCTAGTGCACGTCCAGAACTCGGAGTGGGGCCAGGCCGTTCTGTAGACAGATCACTGATGTATAGTG
AAGCTAACAGACGGGAGACATTTACCTCATGGCCTCATGTAGGCTATAGGTGGGCACAACCAGATCCCATGGCTCAAGCTGGATTTTATC
ATCAGCCTGCCTCATCTGGAGATGATAGAGCCATGTGTTTTACTTGTAGTGTATGCCTCGTTTGTTGGGAACCTACTGATGAACCTTGGT
CTGAACACGAAAGACATTCCCCAAACTGCCCATTTGTGAAAGGTGAGCACACACAGAATGTGCCATTGTCAGTCACTCTTGCAACAAGTC
CTGCACAGTTTCCTTGTACGGATGGAACTGACAGAATATCTTGCTTTGGGTCGGGGAGCTGCCCTCATTTTCTAGCTGCTGCAACTAAAC
GAGGAAAGATCTGCATATGGGATGTTTCCAAACTTATGAAGGTGCACTTAAAGTTTGAAATTAATGCCTATGATCCAGCAATTGTACAAC
AGCTTATTCTATCAGGAGACCCAAGCTCAGGAGTTGATTCAAGGAGACCAACTTTGGCGTGGCTGGAGGACTCCTCTAGTTGCTCAGATA
TACCAAAATTGGAAGGAGATAGTGATGATTTACTGGAGGATTCAGACAGTGAAGAGCATTCCAGATCAGATTCTGTGACAGGGCATACAT
CACAGAAGGAAGCCATGGAAGTAAGCCTTGATATAACAGCACTCAGCATTCTCCAACAGCCAGAAAAACTTCAGTGGGAGATTGTTGCAA
ATGTGCTTGAAGATACTGTTAAGGATCTTGAAGAACTTGGGGCAAATCCTTGTTTAACAAACTCTAAGAGTGAAAAGACAAAGGAAAAGC
ACCAGGAGCAACACAACATTCCTTTTCCATGTTTATTAGCTGGAGGTTTATTAACATATAAATCTCCTGCTACCTCACCCATTAGTAGTA
ATTCTCACAGGTCACTGGATGGTTTAAGCAGAACTCAGGGTGAAAGTATATCAGAACAAGGGTCAACTGACAATGAATCCTGCACTAATT
CAGAACTAAATTCTCCTCTGGTAAGGAGGACTTTACCGGTTTTGCTTCTTTATAGCATCAAGGAATCTGATGAGAAAGCAGGAAAGATCT
TTTCACAGATGAACAATATTATGAGTAAAAGTTTGCATGATGATGGTTTTACTGTTCCACAGATTATTGAAATGGAGCTGGATAGTCAGG
AGCAGTTGTTATTGCAGGATCCTCCTGTGACTTACATTCAGCAATTTGCAGATGCAGCAGCCAACCTTACCTCTCCGGATTCTGAGAAGT
GGAACTCTGTGTTTCCCAAGCCTGGGACTTTGGTTCAGTGCTTGAGGCTGCCAAAGTTTGCAGAGGAGGAGAATCTTTGTATAGACTCAA
TAACTCCTTGTGCTGACGGAATTCATTTGTTGGTAGGACTGCGGACATGCCCTGTTGAATCCTTGAGTGCAATAAATCAAGTAGAGGCCT
TGAATAATTTAAATAAATTAAACTCTGCACTATGTAATAGACGGAAAGGTGAGCTGGAATCAAATCTTGCTGTAGTGAATGGTGCAAATA
TTAGTGTAATCCAACATGAATCACCAGCAGATGTACAGACTCCTTTAATAATTCAGCCTGAGCAGAGGAATGTTAGTGGTGGATATTTAG
TGCTTTATAAAATGAATTATGCCACTCGGATAGTGACTTTAGAAGAGGAGCCAATAAAAATACAACATATCAAAGATCCCCAGGACACAA
TTACCTCGCTCATTTTGCTTCCACCCGATATATTGGATAATCGAGAGGATGACTGTGAGGAACCTATTGAGGACATGCAGTTAACCTCAA
AGAATGGTTTTGAGAGAGAAAAAACGTCTGACATTTCTACTCTTGGACACCTGGTAATAACCACTCAGGGAGGATATGTAAAAATACTAG
ATCTTTCAAACTTTGAAATTTTGGCCAAAGTGGAGCCTCCCAAAAAGGAGGGCACTGAGGAACAGGACACATTTGTTTCTGTGATTTACT
GTTCTGGCACAGACAGGCTGTGTGCATGCACCAAAGGTGGTGAGCTTCATTTTCTCCAAATTGGAGGAACCTGTGATGATATTGATGAAG
CTGATATACTAGTGGATGGATCTCTTTCTAAAGGAATAGAACCATCTTCAGAAGGTTCCAAACCTTTATCAAATCCTTCAAGTCCTGGCA
TTTCAGGAGTTGATTTATTGGTGGACCAGCCATTCACCCTTGAAATCTTGACATCCCTAGTGGAGCTAACCCGCTTTGAGACTTTGACTC
CAAGGTTTTCAGCGACTGTTCCTCCATGCTGGGTAGAAGTTCAACAAGAACAGCAGCAAAGGAGGCATCCTCAACATTTGCATCAGCAAC
ACCATGGTGATGCTGCTCAGCATACTCGAACTTGGAAACTACAGACCGACAGCAACAGCTGGGATGAACATGTATTTGAATTAGTACTAC
CTAAAGCTTGTATGGTTGGACATGTGGACTTCAAATTCGTTTTGAACTCAAACATCACCAATATTCCACAGATACAAGTGACACTGCTGA
AAAATAAAGCTCCAGGATTAGGGAAAGTCAATGCTCTTAACATTGAAGTGGAACAAAATGGGAAACCGTCCCTGGTTGATTTGAATGAAG
AAATGCAGCACATGGATGTAGAGGAATCACAGTGTCTTAGATTATGTCCATTTTTGGAGGATCATAAAGAAGACATTCTATGTGGGCCAG
TATGGCTTGCTAGTGGCCTTGATCTATCAGGGCATGCTGGAATGTTGACGTTAACAAGCCCCAAACTTGTTAAAGGTATGGCAGGAGGAA
AATATCGTTCGTTTTTAATCCATGTCAAGGCAGTGAATGAAAGAGGAACAGAAGAGATTTGTAATGGTGGTATGCGTCCTGTAGTAAGGC
TTCCATCCCTAAAACACCAGAGTAACAAGGGTTATTCACTTGCTTCACTTTTGGCTAAAGTTGCAGCAGGCAAGGAAAAATCATCTAATG
TTAAGAATGAAAATACAAGTGGCACCCGTAAATCTGAAAACCTCCGGGGCTGTGATTTACTTCAAGAGGTCTCAGTCACCATTCGAAGAT
TTAAGAAAACCTCAATTTCTAAGGAAAGAGTGCAACGATGTGCCATGTTACAGTTTTCAGAATTTCATGAGAAGCTTGTTAATACTCTTT
GCAGAAAAACAGATGATGGCCAGATCACAGAACATGCCCAGAGCCTTGTGTTGGATACTCTCTGTTGGTTAGCTGGAGTTCATTCAAATG
GACCCGGAAGCTCAAAGGAAGGAAATGAGAACCTACTTTCAAAAACACGAAAATTTCTGTCAGACATCGTACGTGTTTGCTTCTTTGAGG
CAGGACGAAGTATAGCCCATAAGTGTGCCCGATTTCTAGCCTTGTGCATTAGTAATGGCAAATGTGACCCATGTCAACCAGCATTTGGAC
CTGTTCTGTTGAAGGCTTTACTTGATAATATGTCATTTTTACCTGCAGCAACAACTGGTGGTTCTGTCTATTGGTATTTTGTCTTACTGA
ATTATGTGAAAGATGAAGATCTGGCTGGATGCAGTACAGCTTGTGCATCTTTGCTTACTGCAGTGTCCAGACAGTTACAGGACAGGCTAA
CACCAATGGAGGCTTTACTTCAGACAAGATATGGATTATATAGCTCACCATTTGATCCAGTCCTCTTTGATTTGGAGATGAGTGGCTCTT
CTTGTAAAAATGTTTATAACAGCAGCATTGGTGTCCAGTCAGATGAAATTGATTTATCAGATGTCCTTTCAGGAAATGGAAAGGTCAGTA
GTTGCACAGCTGCTGAGGGTAGTTTCACATCTCTCACTGGACTTTTGGAAGTTGAACCTCTGCACTTTACTTGTGTGTCAACTAGTGATG
GAACCAGAATAGAAAGGGATGATGCAATGAGTTCCTTCGGGGTTACTCCTGCAGTAGGTGGACTATCATCTGGGACAGTTGGGGAAGCCT
CGACAGCCCTGAGTTCAGCAGCCCAGGTAGCTTTGCAGTCTCTCTCTCATGCAATGGCTTCAGCCGAGCAACAGCTACAGGTGCTGCAAG
AGAAACAGCAGCAGCTTTTGAAGCTTCAGCAACAGAAAGCAAAGCTGGAAGCCAAGTTACATCAGACAACAGCTGCAGCAGCTGCAGCAG
CATCAGCAGTAGGTCCTGTTCACAACTCTGTGCCTTCCAACCCAGTGGCTGCCCCTGGATTCTTCATTCATCCATCTGATGTTATTCCAC
CCACTCCAAAAACAACACCTCTTTTTATGACTCCACCACTCACTCCACCCAATGAAGCAGTTTCCGTTGTGATTAATGCCGAACTTGCAC
AGCTTTTCCCAGGCTCAGTCATTGATCCCCCAGCAGTCAATCTTGCTGCACATAACAAAAATTCCAACAAGTCCAGAATGAATCCACTTG
GTTCTGGTCTAGCCCTTGCAATTTCTCATGCTTCACATTTTCTTCAACCTCCGCCTCACCAGTCCATTATTATAGAGCGAATGCATTCAG
GAGCAAGAAGATTTGTGACCTTGGATTTTGGGAGGCCTATATTGTTGACTGATGTATTGATTCCCACTTGTGGAGACTTGGCCTCTTTGT
CAATTGACATTTGGACATTAGGAGAAGAGGTGGATGGAAGGCGGTTGGTAGTGGCAACTGATATAAGCACTCATTCACTAATTCTTCATG
ACTTAATACCACCTCCCGTGTGCAGATTCATGAAGATCACTGTTATTGGACGTTACGGGAGTACAAATGCCAGAGCCAAAATCCCATTAG
GATTTTACTATGGTCATACCTACATCTTGCCTTGGGAAAGTGAACTGAAGTTAATGCATGATCCTCTAAAGGGAGAGGGAGAATCTGCAA
ACCAGCCAGAAATTGACCAGCATTTAGCAATGATGGTTGCTTTGCAGGAGGATATACAGTGCAGGTATAACTTGGCTTGTCATCGTCTGG
AAACCCTTTTGCAAAGTATTGATCTTCCTCCTCTAAACAGTGCTAACAATGCACAGTACTTTTTACGAAAACCAGATAAGGCAGTTGAGG
AAGACAGTAGGGTTTTTTCTGCTTATCAAGATTGTATTCAGCTACAGCTTCAACTAAATTTGGCTCATAATGCAGTGCAGAGGCTCAAAG
TGGCGCTAGGTGCAAGCCGGAAGATGTTGAGTGAAACATCAAATCCAGAAGATTTAATTCAGACATCTTCCACAGAGCAGTTACGTACTA
TCATCAGATATTTACTGGACACTTTGCTCAGCCTGCTTCATGCTTCTAATGGACACTCTGTTCCTGCAGTTTTGCAGAGCACATTTCATG
CCCAGGCCTGTGAAGAGCTCTTTAAACACTTGTGCATCAGTGGAACCCCAAAGATACGGTTACATACTGGTCTTCTTCTTGTTCAACTGT
GTGGTGGTGAAAGGTGGTGGGGTCAATTTCTTTCTAATGTCCTTCAGGAATTGTACAATTCGGAACAGCTTCTCATCTTTCCACAGGATA
GGGTCTTCATGTTACTTTCCTGCATTGGTCAAAGATCACTTAGTAATAGTGGAGTATTAGAAAGCTTACTTAATCTCTTGGATAATTTAT
TGTCACCTCTTCAGCCACAGTTACCCATGCATAGGAGGACAGAAGGAGTACTAGATATTCCCATGATCAGTTGGGTTGTTATGCTGGTGT
CCAGGTTGCTGGATTATGTGGCAACTGTTGAAGATGAAGCAGCAGCTGCAAAGAAACCTTTGAATGGTAATCAGTGGAGTTTTATTAACA
ATAATCTACACACTCAGAGCTTAAATAGATCTTCTAAAGGCAGCAGTAGCCTTGATAGATTATATTCCAGAAAAATCAGAAAGCAGCTTG
TTCATCATAAACAGCAACTTAACCTACTAAAAGCAAAGCAGAAGGCATTGGTAGAACAGATGGAAAAAGAAAAAATACAAAGTAACAAAG
GATCATCATATAAACTCCTGGTAGAACAAGCAAAACTAAAGCAGGCCACTTCAAAGCACTTTAAGGATTTAATTCGTTTACGTCGGACAG
CAGAATGGTCCCGTTCTAATTTAGACACAGAAGTTACAACAGCAAAAGAAAGTCCTGAGATAGAACCACTTCCATTTACTCTGGCCCATG
AGCGTTGTATCTCAGTAGTCCAGAAACTTGTTCTGTTTCTTCTCTCCATGGACTTTACATGTCATGCAGATCTCTTATTGTTTGTTTGTA
AGGTTCTTGCACGCATTGCAAATGCCACGAGGCCAACTATTCATCTGTGTGAGATTGTGAACGAACCCCAGCTGGAAAGACTGCTGTTAC
TTTTGGTTGGAACTGACTTCAATAGAGGAGATATATCTTGGGGTGGTGCTTGGGCTCAGTATTCCTTAACTTGCATGCTACAAGATATTT
TAGCAGGAGAATTACTGGCTCCAGTAGCCGCAGAAGCCATGGAGGAAGGAACAGTGGGTGATGATGTAGGTGCGACAGCTGGTGACTCTG
ATGACTCCCTTCAACAGTCCTCAGTTCAGTTGCTGGAAACTATAGATGAACCTTTGACACATGACATAACAGGTGCACCTCCTCTGTCCT
CTTTGGAAAAAGATAAAGAAATTGACCTTGAGTTACTTCAGGATCTAATGGAAGTTGACATTGATCCTTTAGATATTGATTTGGAAAAGG
ACCCTCTTGCAGCCAAGGTTTTTAAGCCAATAAGCAGTACATGGTATGATTATTGGGGTGCTGATTATGGGACCTACAATTACAACCCTT
ACATTGGAGGTCTGGGAATTCCTGTAGCAAAGCCACCAGCAAACACGGAGAAGAACGGATCACAGACAGTTAGCGTTTCAGTCTCTCAGG
CCCTGGATGCTCGCCTAGAAGTTGGACTTGAACAGCAAGCAGAACTGATGTTGAAAATGATGTCTACTCTGGAGGCAGATTCCATTTTAC
AGGCATTAACAAATACATCTCCTACATTATCACAGTCTCCCACTGGAACAGATGATTCACTTCTAGGGGGTTTACAAGCAGCAAACCAAA
CCAGCCAGCTTATTATACAGTTATCATCTGTCCCAATGTTAAATGTTTGTTTCAACAAACTTTTTTCCATGCTTCAAGTCCATCATGTTC
AGTTGGAGTCACTTCTCCAATTGTGGCTCACACTGAGCCTGAATTCTAGTTCAACTGGAAACAAAGAAAATGGAGCAGACATATTTTTAT
ATAATGCTAATAGGATACCTGTTATTTCATTAAATCAAGCATCAATAACTAGCTTTCTCACAGTGTTAGCTTGGTATCCCAATACTTTGC
TCCGGACATGGTGCCTTGTGCTTCATAGCCTAACACTCATGACAAACATGCAGCTTAATTCTGGTTCCAGCAGTGCCATTGGAACTCAGG
AGAGTACTGCTCATTTGTTGGTTTCAGATCCAAACCTAATTCATGTATTAGTGAAATTTCTTTCTGGCACCAGTCCACATGGAACAAATC
AACACAGTCCACAGGTTGGTCCTACAGCTACACAAGCTATGCAAGAATTTCTTACTCGATTACAAGTGCATCTTTCTTCAACATGTCCTC
AGATATTCAGTGAATTTTTGCTCAAGCTAATTCATATACTTTCAACTGAAAGGGGTGCTTTCCAGACAGGCCAAGGACCTCTCGATGCCC
AAGTGAAGCTCTTAGAATTCACTCTGGAGCAGAATTTTGAAGTCGTTTCAGTTAGTACTATTTCTGCCGTGATAGAATCGGTTACATTTT
TAGTGCACCACTATATCACTTGCTCAGACAAAGTAATGTCAAGAAGTGGATCAGATAGCTCCGTGGGTGCTCGAGCATGCTTTGGGGGAC
TCTTTGCCAATCTTATTCGTCCGGGTGATGCAAAAGCAGTTTGTGGCGAAATGACAAGAGATCAACTCATGTTTGATTTGTTAAAACTTG
TTAACATTTTAGTGCAGCTGCCTCTTTCAGGCAATAGGGAATACAGTGCAAGAGTGTCTGTGACCACAAATACAACAGATAGTGTTTCAG
ATGAAGAAAAAGTCTCAGGAGGCAAAGATGGCAATGGAAGCAGTACCAGTGTTCAAGGATCGCCTGCATATGTTGCTGACTTAGTCTTAG
CCAACCAACAAATTATGAGCCAGATTTTGTCTGCTCTGGGCCTGTGTAATAGCAGTGCCATGGCAATGATAATTGGAGCAAGTGGATTAC
ATCTCACTAAACATGAAAACTTTCATGGTGGGTTGGATGCCATATCAGTTGGGGATGGATTATTTACCATACTGACAACCCTTAGTAAAA
AAGCTTCTACAGTCCACATGATGCTGCAGCCAATTTTAACATACATGGCCTGTGGATATATGGGCAGACAAGGCTCTCTTGCTACTTGCC
AGTTATCTGAGCCATTATTGTGGTTCATTTTGAGAGTATTGGATACTAGTGATGCCTTGAAAGCATTTCATGATATGGGTGGTGTTCAGC
TCATATGCAATAATATGGTTACTAGTACAAGGGCTATTGTGAACACTGCAAGAAGTATGGTATCAACTATTATGAAATTTCTTGACTCTG
GTCCAAATAAAGCTGTTGACAGCACATTGAAAACAAGAATACTAGCTTCTGAGCCTGACAATGCTGAAGGGATTCATAACTTTGCACCCC
TCGGTACAATCACATCTAGCAGTCCTACTGCCCAACCAGCTGAAGTGCTATTGCAGGCCACACCTCCTCACAGAAGAGCTCGCTCTGCTG
CTTGGTCCTACATCTTTCTTCCAGAGGAGGCTTGGTGTGACCTTACCATTCACCTTCCTGCAGCAGTGCTGCTTAAGGAGATACATATCC
AGCCTCATCTTGCATCTCTTGCAACCTGCCCTTCCTCAGTGTCTGTTGAAGTAAGTGCAGATGGGGTAAATATGCTACCTTTGTCCACTC
CTGTTGTCACAAGTGGCCTCACCTACATAAAAATTCAGCTTGTAAAAGCCGAAGTAGCTTCTGCTGTCTGCCTTAGACTACATCGTCCAC
GGGATGCCAGCACATTAGGCCTTTCACAAATTAAATTATTGGGGCTCACTGCTTTTGGTACCACCTCTTCTGCAACAGTTAATAATCCAT
TCCTTCCATCTGAAGATCAGGTATCCAAAACAAGTATTGGATGGTTACGGTTATTACATCATTGCCTTACTCACATAAGTGATCTAGAAG
GAATGATGGCAAGTGCAGCTGCACCTACTGCTAATCTGCTGCAGACTTGTGCGGCCTTATTGATGTCACCTTACTGTGGAATGCATTCAC
CCAACATCGAGGTTGTGCTTGTAAAGATAGGACTGCAGTCTACTAGAATTGGCCTGAAGCTCATAGACATTCTCCTGAGAAATTGTGCAG
CATCAGGCAGTGATCCTACAGATTTGAATAGTCCTTTACTTTTTGGAAGACTAAATGGACTCTCTTCTGACTCTACGATAGATATTCTTT
ACCAGCTTGGAACAACTCAGGATCCTGGTACAAAAGACAGAATTCAGGCCTTGTTAAAATGGGTTAGTGATTCTGCAAGAGTGGCTGCTA
TGAAGAGAAGTGGCAGGATGAACTACATGTGTCCTAACTCCTCAACAGTAGAGTATGGTCTTCTGATGCCATCTCCTTCTCATTTGCACT
GTGTAGCAGCCATTCTGTGGCATAGTTATGAGCTGCTTGTAGAATATGACTTACCAGCACTCCTGGACCAAGAGCTCTTTGAGTTACTTT
TTAATTGGTCCATGTCTCTTCCCTGCAATATGGTTTTGAAGAAAGCTGTTGACAGTCTACTTTGCTCAATGTGTCACGTACACCCAAACT
ATTTTTCTTTGCTCATGGGCTGGATGGGAATTACCCCTCCTCCAGTGCAATGTCATCATAGACTGTCCATGACAGATGATAGCAAAAAGC
AGGATCTTAGTTCATCTTTAACAGATGACTCTAAAAATGCACAAGCACCTCTCGCATTAACTGAATCACATTTGGCTACCCTTGCTTCCT
CTTCTCAATCTCCTGAAGCTATTAAACAATTACTAGACTCAGGTTTGCCTTCTCTTCTTGTGAGGAGTCTGGCTAGTTTCTGCTTTAGCC
ACATTTCTAGCTCAGAAAGCATTGCCCAGTCAATAGATATTTCCCAGGACAAACTCAGGCGCCATCATGTCCCACAACAATGTAATAAGA
TGCCTATCACAGCCGACCTAGTTGCTCCTATTCTTAGGTTTTTGACAGAAGTTGGCAATAGCCATATTATGAAAGATTGGCTTGGTGGTT
CTGAAGTCAATCCACTATGGACAGCACTTCTGTTTTTATTGTGTCACTCTGGGTCCACTTCTGGAAGCCATAATTTAGGTGCACAACAGA
CCAGTGCAAGATCAGCTTCTCTTTCTTCAGCTGCTACAACAGGACTGACTACTCAACAGCGCACAGCAATTGAGAATGCAACTGTTGCGT
TCTTTCTACAGTGCATTTCATGCCATCCTAATAATCAAAAGCTGATGGCACAGGTTCTTTGTGAACTATTTCAGACATCTCCTCAAAGAG
GGAACCTTCCAACATCTGGGAACATTTCAGGGTTTATACGAAGATTATTTTTACAGTTGATGCTGGAAGATGAGAAAGTGACAATGTTTC
TTCAGTCTCCATGTCCACTGTACAAAGGTAGAATTAATGCTACTAGCCACGTCATCCAGCATCCAATGTATGGAGCAGGCCACAAATTCC
GTACTCTTCATTTGCCAGTCTCAACAACATTATCAGATGTTCTTGACAGAGTGTCAGATACTCCAAGTATCACAGCTAAATTAATTAGTG
AACAAAAAGATGACAAAGAAAAGAAAAACCATGAAGAGAAAGAAAAAGTTAAAGCGGAAAATGGATTTCAAGACAATTACAGTGTTGTTG
TTGCCTCTGGGCTGAAGTCTCAATCTAAACGTGCTGTGTCAGCTACACCACCTCGCCCACCATCCAGGAGGGGGAGGACAATACCTGATA
AAATAGGAAGTACTTCAGGAGCAGAGGCTGCCAACAAAATAATTACTGTCCCAGTGTTTCACCTGTTTCACAAACTCTTGGCAGGCCAGC
CATTGCCAGCTGAAATGACACTTGCCCAGCTTTTAACTCTCCTATATGACCGAAAACTTCCTCAGGGTTACCGCTCAATAGATCTGACTG
TTAAATTGGGATCAAGAGTTATAACAGACCCCAGTCTATCAAAAACAGATTCTTATAAAAGACTACACCCTGAAAAAGATCATGGAGACT
TACTTGCTAGCTGTCCAGAAGATGAGGCTCTCACTCCAGGTGATGAATGCATGGATGGGATACTGGATGAATCTTTGCTTGAAACCTGTC
CAATTCAGTCACCATTACAAGTTTTTGCAGGAATGGGTGGACTGGCTCTTATTGCTGAAAGACTACCCATGCTATATCCAGAAGTAATTC
AACAGGTGAGTGCTCCAGTTGTAACATCTACCACTCAGGAAAAGCCGAAGGATAGCGATCAGTTTGAATGGGTGACCATTGAACAGTCAG
GGGAGTTAGTTTATGAAGCACCAGAAACTGTTGCGGCTGAACCTCCACCTATCAAGTCAGCAGTACAGACCATGTCTCCCATACCTGCCC
ATTCTTTGGCTGCTTTTGGATTATTTCTTCGTCTTCCGGGCTATGCGGAAGTGCTACTGAAAGAGAGAAAACATGCCCAGTGCCTTCTTC
GATTGGTATTGGGAGTGACAGATGATGGAGAAGGAAGTGCTTTGGGAAAAAGAACACGGTTCCAGGAAAATTATGTGGCACAACTGATTC
TAGATGTAAGAAGGGAAGGGGATGTCCTTTCAAATTGTGAATTCACTCCAGCACCCACTCCTCAGGAACATTTAACCAAGAATCTTGAGC
TCAATGATGACACCATTCTGAATGACATAAAGTTAGCAGATTGTGAACAGTTCCAGATGCCGGATCTGTGTGCTGAAGAGATCGCTATTA
TTCTTGGAATCTGCACTAATTTTCAAAAGAATAACCCAGTGCACACATTAACTGAAGTGGAGCTTCTGGCATTTACATCATGTTTGCTTT
CACAACCAAAGTTCTGGGCCATTCAGACATCAGCCTTGATCCTCCGGACAAAACTTGAGAAAGGAAGTACTCGCCGAGTGGAACGGGCAA
TGAGGCAGACACAGGCTCTTGCAGACCAATTTGAAGATAAAACTACATCTGTATTGGAACGCCTGAAGATTTTCTATTGCTGTCAAGTAC
CACCTCACTGGGCCATTCAGCGCCAACTTGCAAGTTTGCTCTTTGAGTTGGGATGTACCAGTTCAGCCCTTCAGATATTTGAAAAGCTAG
AAATGTGGGAAGATGTTGTCATTTGTTATGAAAGAGCCGGGCAGCACGGAAAGGCAGAAGAAATCCTTAGACAAGAGCTGGAGAAAAAAG
AAACGCCTAGTTTATACTGCTTGCTTGGAGATGTCCTCGGAGACCATTCTTGCTATGACAAGGCCTGGGAGTTGTCCCGGTACCGCAGTG
CTCGTGCTCAGCGCTCCAAAGCCCTCCTTCATCTTCGGAACAAGGAGTTTCAAGAGTGTGTAGAGTGCTTCGAACGCTCGGTTAAGATTA
ATCCCATGCAGCTCGGGGTGTGGTTTTCTCTCGGTTGTGCCTATTTGGCCTTGGAAGACTATCAAGGTTCAGCAAAGGCATTTCAGCGCT
GTGTGACTCTAGAACCCGATAATGCTGAAGCTTGGAACAATTTGTCAACTTCCTATATCCGATTAAAACAAAAAGTAAAAGCTTTTAGAA
CTTTACAAGAAGCTCTCAAGTGTAACTATGAACACTGGCAGATTTGGGAAAACTACATCCTCACCAGCACTGACGTTGGGGAATTTTCAG
AAGCCATTAAAGCTTATCACCGGCTCTTGGACTTACGTGACAAATACAAAGATGTTCAGGTCCTTAAAATTCTAGTCAGGGCAGTGATTG
ATGGGATGACTGATCGAAGTGGAGATGTTGCAACTGGCCTCAAAGGAAAGCTGCAGGAGTTATTTGGCAGAGTGACTTCAAGAGTGACAA
ATGATGGAGAAATCTGGAGGCTGTATGCCCACGTATATGGAAATGGGCAGAGTGAAAAGCCTGATGAAAATGAAAAGGCATTCCAGTGCC
TCTCAAAGGCATACAAGTGTGACACCCAGTCCAATTGTTGGGAGAAAGATATTACATCATTTAAGGAAGTTGTTCAAAGAGCCTTAGGAC
TTGCACATGTGGCCATAAAATGCAGTAAAAACAAATCCAGTTCCCAAGAAGCTGTACAAATGCTTTCTTCTGTTCGACTCAATTTACGGG
GCTTGTTATCTAAAGCAAAGCAACTTTTTACAGATGTGGCAACTGGAGAAATGTCCAGGGAATTAGCTGATGACATAACAGCTATGGACA
CCTTAGTGACAGAGCTCCAAGACCTAAGCAACCAGTTTCGAAATCAGTATTGATTCTGCTGGAAGCAGATTCTGGAAAAGGTGCTTTCAC

>9769_9769_4_BIRC6-TTC27_BIRC6_chr2_32768608_ENST00000421745_TTC27_chr2_32891701_ENST00000317907_length(amino acids)=4772AA_BP=0
MVTGGGAAPPGTVTEPLPSVIVLSAGRKMAAAAAAASGPGCSSAAGAGAAGVSEWLVLRDGCMHCDADGLHSLSYHPALNAILAVTSRGT
IKVIDGTSGATLQASALSAKPGGQVKCQYISAVDKVIFVDDYAVGCRKDLNGILLLDTALQTPVSKQDDVVQLELPVTEAQQLLSACLEK
VDISSTEGYDLFITQLKDGLKNTSHETAANHKVAKWATVTFHLPHHVLKSIASAIVNELKKINQNVAALPVASSVMDRLSYLLPSARPEL
GVGPGRSVDRSLMYSEANRRETFTSWPHVGYRWAQPDPMAQAGFYHQPASSGDDRAMCFTCSVCLVCWEPTDEPWSEHERHSPNCPFVKG
EHTQNVPLSVTLATSPAQFPCTDGTDRISCFGSGSCPHFLAAATKRGKICIWDVSKLMKVHLKFEINAYDPAIVQQLILSGDPSSGVDSR
RPTLAWLEDSSSCSDIPKLEGDSDDLLEDSDSEEHSRSDSVTGHTSQKEAMEVSLDITALSILQQPEKLQWEIVANVLEDTVKDLEELGA
NPCLTNSKSEKTKEKHQEQHNIPFPCLLAGGLLTYKSPATSPISSNSHRSLDGLSRTQGESISEQGSTDNESCTNSELNSPLVRRTLPVL
LLYSIKESDEKAGKIFSQMNNIMSKSLHDDGFTVPQIIEMELDSQEQLLLQDPPVTYIQQFADAAANLTSPDSEKWNSVFPKPGTLVQCL
RLPKFAEEENLCIDSITPCADGIHLLVGLRTCPVESLSAINQVEALNNLNKLNSALCNRRKGELESNLAVVNGANISVIQHESPADVQTP
LIIQPEQRNVSGGYLVLYKMNYATRIVTLEEEPIKIQHIKDPQDTITSLILLPPDILDNREDDCEEPIEDMQLTSKNGFEREKTSDISTL
GHLVITTQGGYVKILDLSNFEILAKVEPPKKEGTEEQDTFVSVIYCSGTDRLCACTKGGELHFLQIGGTCDDIDEADILVDGSLSKGIEP
SSEGSKPLSNPSSPGISGVDLLVDQPFTLEILTSLVELTRFETLTPRFSATVPPCWVEVQQEQQQRRHPQHLHQQHHGDAAQHTRTWKLQ
TDSNSWDEHVFELVLPKACMVGHVDFKFVLNSNITNIPQIQVTLLKNKAPGLGKVNALNIEVEQNGKPSLVDLNEEMQHMDVEESQCLRL
CPFLEDHKEDILCGPVWLASGLDLSGHAGMLTLTSPKLVKGMAGGKYRSFLIHVKAVNERGTEEICNGGMRPVVRLPSLKHQSNKGYSLA
SLLAKVAAGKEKSSNVKNENTSGTRKSENLRGCDLLQEVSVTIRRFKKTSISKERVQRCAMLQFSEFHEKLVNTLCRKTDDGQITEHAQS
LVLDTLCWLAGVHSNGPGSSKEGNENLLSKTRKFLSDIVRVCFFEAGRSIAHKCARFLALCISNGKCDPCQPAFGPVLLKALLDNMSFLP
AATTGGSVYWYFVLLNYVKDEDLAGCSTACASLLTAVSRQLQDRLTPMEALLQTRYGLYSSPFDPVLFDLEMSGSSCKNVYNSSIGVQSD
EIDLSDVLSGNGKVSSCTAAEGSFTSLTGLLEVEPLHFTCVSTSDGTRIERDDAMSSFGVTPAVGGLSSGTVGEASTALSSAAQVALQSL
SHAMASAEQQLQVLQEKQQQLLKLQQQKAKLEAKLHQTTAAAAAAASAVGPVHNSVPSNPVAAPGFFIHPSDVIPPTPKTTPLFMTPPLT
PPNEAVSVVINAELAQLFPGSVIDPPAVNLAAHNKNSNKSRMNPLGSGLALAISHASHFLQPPPHQSIIIERMHSGARRFVTLDFGRPIL
LTDVLIPTCGDLASLSIDIWTLGEEVDGRRLVVATDISTHSLILHDLIPPPVCRFMKITVIGRYGSTNARAKIPLGFYYGHTYILPWESE
LKLMHDPLKGEGESANQPEIDQHLAMMVALQEDIQCRYNLACHRLETLLQSIDLPPLNSANNAQYFLRKPDKAVEEDSRVFSAYQDCIQL
QLQLNLAHNAVQRLKVALGASRKMLSETSNPEDLIQTSSTEQLRTIIRYLLDTLLSLLHASNGHSVPAVLQSTFHAQACEELFKHLCISG
TPKIRLHTGLLLVQLCGGERWWGQFLSNVLQELYNSEQLLIFPQDRVFMLLSCIGQRSLSNSGVLESLLNLLDNLLSPLQPQLPMHRRTE
GVLDIPMISWVVMLVSRLLDYVATVEDEAAAAKKPLNGNQWSFINNNLHTQSLNRSSKGSSSLDRLYSRKIRKQLVHHKQQLNLLKAKQK
ALVEQMEKEKIQSNKGSSYKLLVEQAKLKQATSKHFKDLIRLRRTAEWSRSNLDTEVTTAKESPEIEPLPFTLAHERCISVVQKLVLFLL
SMDFTCHADLLLFVCKVLARIANATRPTIHLCEIVNEPQLERLLLLLVGTDFNRGDISWGGAWAQYSLTCMLQDILAGELLAPVAAEAME
EGTVGDDVGATAGDSDDSLQQSSVQLLETIDEPLTHDITGAPPLSSLEKDKEIDLELLQDLMEVDIDPLDIDLEKDPLAAKVFKPISSTW
YDYWGADYGTYNYNPYIGGLGIPVAKPPANTEKNGSQTVSVSVSQALDARLEVGLEQQAELMLKMMSTLEADSILQALTNTSPTLSQSPT
GTDDSLLGGLQAANQTSQLIIQLSSVPMLNVCFNKLFSMLQVHHVQLESLLQLWLTLSLNSSSTGNKENGADIFLYNANRIPVISLNQAS
ITSFLTVLAWYPNTLLRTWCLVLHSLTLMTNMQLNSGSSSAIGTQESTAHLLVSDPNLIHVLVKFLSGTSPHGTNQHSPQVGPTATQAMQ
EFLTRLQVHLSSTCPQIFSEFLLKLIHILSTERGAFQTGQGPLDAQVKLLEFTLEQNFEVVSVSTISAVIESVTFLVHHYITCSDKVMSR
SGSDSSVGARACFGGLFANLIRPGDAKAVCGEMTRDQLMFDLLKLVNILVQLPLSGNREYSARVSVTTNTTDSVSDEEKVSGGKDGNGSS
TSVQGSPAYVADLVLANQQIMSQILSALGLCNSSAMAMIIGASGLHLTKHENFHGGLDAISVGDGLFTILTTLSKKASTVHMMLQPILTY
MACGYMGRQGSLATCQLSEPLLWFILRVLDTSDALKAFHDMGGVQLICNNMVTSTRAIVNTARSMVSTIMKFLDSGPNKAVDSTLKTRIL
ASEPDNAEGIHNFAPLGTITSSSPTAQPAEVLLQATPPHRRARSAAWSYIFLPEEAWCDLTIHLPAAVLLKEIHIQPHLASLATCPSSVS
VEVSADGVNMLPLSTPVVTSGLTYIKIQLVKAEVASAVCLRLHRPRDASTLGLSQIKLLGLTAFGTTSSATVNNPFLPSEDQVSKTSIGW
LRLLHHCLTHISDLEGMMASAAAPTANLLQTCAALLMSPYCGMHSPNIEVVLVKIGLQSTRIGLKLIDILLRNCAASGSDPTDLNSPLLF
GRLNGLSSDSTIDILYQLGTTQDPGTKDRIQALLKWVSDSARVAAMKRSGRMNYMCPNSSTVEYGLLMPSPSHLHCVAAILWHSYELLVE
YDLPALLDQELFELLFNWSMSLPCNMVLKKAVDSLLCSMCHVHPNYFSLLMGWMGITPPPVQCHHRLSMTDDSKKQDLSSSLTDDSKNAQ
APLALTESHLATLASSSQSPEAIKQLLDSGLPSLLVRSLASFCFSHISSSESIAQSIDISQDKLRRHHVPQQCNKMPITADLVAPILRFL
TEVGNSHIMKDWLGGSEVNPLWTALLFLLCHSGSTSGSHNLGAQQTSARSASLSSAATTGLTTQQRTAIENATVAFFLQCISCHPNNQKL
MAQVLCELFQTSPQRGNLPTSGNISGFIRRLFLQLMLEDEKVTMFLQSPCPLYKGRINATSHVIQHPMYGAGHKFRTLHLPVSTTLSDVL
DRVSDTPSITAKLISEQKDDKEKKNHEEKEKVKAENGFQDNYSVVVASGLKSQSKRAVSATPPRPPSRRGRTIPDKIGSTSGAEAANKII
TVPVFHLFHKLLAGQPLPAEMTLAQLLTLLYDRKLPQGYRSIDLTVKLGSRVITDPSLSKTDSYKRLHPEKDHGDLLASCPEDEALTPGD
ECMDGILDESLLETCPIQSPLQVFAGMGGLALIAERLPMLYPEVIQQVSAPVVTSTTQEKPKDSDQFEWVTIEQSGELVYEAPETVAAEP
PPIKSAVQTMSPIPAHSLAAFGLFLRLPGYAEVLLKERKHAQCLLRLVLGVTDDGEGSALGKRTRFQENYVAQLILDVRREGDVLSNCEF
TPAPTPQEHLTKNLELNDDTILNDIKLADCEQFQMPDLCAEEIAIILGICTNFQKNNPVHTLTEVELLAFTSCLLSQPKFWAIQTSALIL
RTKLEKGSTRRVERAMRQTQALADQFEDKTTSVLERLKIFYCCQVPPHWAIQRQLASLLFELGCTSSALQIFEKLEMWEDVVICYERAGQ
HGKAEEILRQELEKKETPSLYCLLGDVLGDHSCYDKAWELSRYRSARAQRSKALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAY
LALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRDK
YKDVQVLKILVRAVIDGMTDRSGDVATGLKGKLQELFGRVTSRVTNDGEIWRLYAHVYGNGQSEKPDENEKAFQCLSKAYKCDTQSNCWE
KDITSFKEVVQRALGLAHVAIKCSKNKSSSQEAVQMLSSVRLNLRGLLSKAKQLFTDVATGEMSRELADDITAMDTLVTELQDLSNQFRN

--------------------------------------------------------------
>9769_9769_5_BIRC6-TTC27_BIRC6_chr2_32768608_ENST00000421745_TTC27_chr2_32891702_ENST00000317907_length(transcript)=14566nt_BP=12726nt
TCCCTGCTTCTCCCCCTCTCCCGTCAGCCTCCCTCCGAGTTTGGCCCCTCCGGCCGGGCGATCGACGTTCCGCGTGCGTGCGGGCGCCTG
ACTTCACTTCCGGCTAACGCGCTCGGCTTGCCCCCTGGCCCCGGATGGTGACTGGTGGTGGTGCTGCACCTCCCGGGACTGTCACTGAGC
CGCTTCCCAGTGTGATTGTGCTGAGCGCAGGCCGGAAGATGGCGGCTGCGGCTGCGGCGGCCTCGGGCCCCGGCTGCTCCTCGGCGGCGG
GGGCGGGGGCGGCCGGGGTCTCAGAGTGGCTGGTGCTGCGGGACGGCTGCATGCACTGCGACGCCGACGGGCTGCACAGCCTGTCCTACC
ACCCTGCGCTCAACGCCATCCTGGCCGTCACTAGCCGCGGGACCATCAAAGTCATCGACGGCACCTCGGGGGCCACACTGCAGGCCTCCG
CGCTCAGTGCTAAACCAGGTGGACAGGTGAAATGTCAGTATATCTCTGCTGTGGATAAAGTTATATTTGTGGATGATTATGCAGTAGGGT
GTAGGAAGGACCTTAATGGAATCTTGTTGTTAGACACTGCTCTGCAAACTCCAGTTTCAAAGCAGGATGATGTGGTTCAGCTTGAATTAC
CCGTTACAGAGGCACAGCAGCTCTTATCAGCATGTTTAGAAAAGGTAGATATTTCTAGTACAGAGGGTTATGATTTGTTCATCACACAGC
TCAAAGATGGTTTAAAAAATACATCTCATGAGACTGCAGCAAACCACAAAGTTGCTAAGTGGGCCACAGTTACATTTCATCTTCCTCATC
ATGTGTTGAAGTCCATTGCCAGTGCCATTGTAAATGAACTCAAGAAAATAAATCAAAATGTTGCTGCCTTACCTGTGGCGTCCTCAGTGA
TGGACAGATTGTCTTACCTCTTACCTAGTGCACGTCCAGAACTCGGAGTGGGGCCAGGCCGTTCTGTAGACAGATCACTGATGTATAGTG
AAGCTAACAGACGGGAGACATTTACCTCATGGCCTCATGTAGGCTATAGGTGGGCACAACCAGATCCCATGGCTCAAGCTGGATTTTATC
ATCAGCCTGCCTCATCTGGAGATGATAGAGCCATGTGTTTTACTTGTAGTGTATGCCTCGTTTGTTGGGAACCTACTGATGAACCTTGGT
CTGAACACGAAAGACATTCCCCAAACTGCCCATTTGTGAAAGGTGAGCACACACAGAATGTGCCATTGTCAGTCACTCTTGCAACAAGTC
CTGCACAGTTTCCTTGTACGGATGGAACTGACAGAATATCTTGCTTTGGGTCGGGGAGCTGCCCTCATTTTCTAGCTGCTGCAACTAAAC
GAGGAAAGATCTGCATATGGGATGTTTCCAAACTTATGAAGGTGCACTTAAAGTTTGAAATTAATGCCTATGATCCAGCAATTGTACAAC
AGCTTATTCTATCAGGAGACCCAAGCTCAGGAGTTGATTCAAGGAGACCAACTTTGGCGTGGCTGGAGGACTCCTCTAGTTGCTCAGATA
TACCAAAATTGGAAGGAGATAGTGATGATTTACTGGAGGATTCAGACAGTGAAGAGCATTCCAGATCAGATTCTGTGACAGGGCATACAT
CACAGAAGGAAGCCATGGAAGTAAGCCTTGATATAACAGCACTCAGCATTCTCCAACAGCCAGAAAAACTTCAGTGGGAGATTGTTGCAA
ATGTGCTTGAAGATACTGTTAAGGATCTTGAAGAACTTGGGGCAAATCCTTGTTTAACAAACTCTAAGAGTGAAAAGACAAAGGAAAAGC
ACCAGGAGCAACACAACATTCCTTTTCCATGTTTATTAGCTGGAGGTTTATTAACATATAAATCTCCTGCTACCTCACCCATTAGTAGTA
ATTCTCACAGGTCACTGGATGGTTTAAGCAGAACTCAGGGTGAAAGTATATCAGAACAAGGGTCAACTGACAATGAATCCTGCACTAATT
CAGAACTAAATTCTCCTCTGGTAAGGAGGACTTTACCGGTTTTGCTTCTTTATAGCATCAAGGAATCTGATGAGAAAGCAGGAAAGATCT
TTTCACAGATGAACAATATTATGAGTAAAAGTTTGCATGATGATGGTTTTACTGTTCCACAGATTATTGAAATGGAGCTGGATAGTCAGG
AGCAGTTGTTATTGCAGGATCCTCCTGTGACTTACATTCAGCAATTTGCAGATGCAGCAGCCAACCTTACCTCTCCGGATTCTGAGAAGT
GGAACTCTGTGTTTCCCAAGCCTGGGACTTTGGTTCAGTGCTTGAGGCTGCCAAAGTTTGCAGAGGAGGAGAATCTTTGTATAGACTCAA
TAACTCCTTGTGCTGACGGAATTCATTTGTTGGTAGGACTGCGGACATGCCCTGTTGAATCCTTGAGTGCAATAAATCAAGTAGAGGCCT
TGAATAATTTAAATAAATTAAACTCTGCACTATGTAATAGACGGAAAGGTGAGCTGGAATCAAATCTTGCTGTAGTGAATGGTGCAAATA
TTAGTGTAATCCAACATGAATCACCAGCAGATGTACAGACTCCTTTAATAATTCAGCCTGAGCAGAGGAATGTTAGTGGTGGATATTTAG
TGCTTTATAAAATGAATTATGCCACTCGGATAGTGACTTTAGAAGAGGAGCCAATAAAAATACAACATATCAAAGATCCCCAGGACACAA
TTACCTCGCTCATTTTGCTTCCACCCGATATATTGGATAATCGAGAGGATGACTGTGAGGAACCTATTGAGGACATGCAGTTAACCTCAA
AGAATGGTTTTGAGAGAGAAAAAACGTCTGACATTTCTACTCTTGGACACCTGGTAATAACCACTCAGGGAGGATATGTAAAAATACTAG
ATCTTTCAAACTTTGAAATTTTGGCCAAAGTGGAGCCTCCCAAAAAGGAGGGCACTGAGGAACAGGACACATTTGTTTCTGTGATTTACT
GTTCTGGCACAGACAGGCTGTGTGCATGCACCAAAGGTGGTGAGCTTCATTTTCTCCAAATTGGAGGAACCTGTGATGATATTGATGAAG
CTGATATACTAGTGGATGGATCTCTTTCTAAAGGAATAGAACCATCTTCAGAAGGTTCCAAACCTTTATCAAATCCTTCAAGTCCTGGCA
TTTCAGGAGTTGATTTATTGGTGGACCAGCCATTCACCCTTGAAATCTTGACATCCCTAGTGGAGCTAACCCGCTTTGAGACTTTGACTC
CAAGGTTTTCAGCGACTGTTCCTCCATGCTGGGTAGAAGTTCAACAAGAACAGCAGCAAAGGAGGCATCCTCAACATTTGCATCAGCAAC
ACCATGGTGATGCTGCTCAGCATACTCGAACTTGGAAACTACAGACCGACAGCAACAGCTGGGATGAACATGTATTTGAATTAGTACTAC
CTAAAGCTTGTATGGTTGGACATGTGGACTTCAAATTCGTTTTGAACTCAAACATCACCAATATTCCACAGATACAAGTGACACTGCTGA
AAAATAAAGCTCCAGGATTAGGGAAAGTCAATGCTCTTAACATTGAAGTGGAACAAAATGGGAAACCGTCCCTGGTTGATTTGAATGAAG
AAATGCAGCACATGGATGTAGAGGAATCACAGTGTCTTAGATTATGTCCATTTTTGGAGGATCATAAAGAAGACATTCTATGTGGGCCAG
TATGGCTTGCTAGTGGCCTTGATCTATCAGGGCATGCTGGAATGTTGACGTTAACAAGCCCCAAACTTGTTAAAGGTATGGCAGGAGGAA
AATATCGTTCGTTTTTAATCCATGTCAAGGCAGTGAATGAAAGAGGAACAGAAGAGATTTGTAATGGTGGTATGCGTCCTGTAGTAAGGC
TTCCATCCCTAAAACACCAGAGTAACAAGGGTTATTCACTTGCTTCACTTTTGGCTAAAGTTGCAGCAGGCAAGGAAAAATCATCTAATG
TTAAGAATGAAAATACAAGTGGCACCCGTAAATCTGAAAACCTCCGGGGCTGTGATTTACTTCAAGAGGTCTCAGTCACCATTCGAAGAT
TTAAGAAAACCTCAATTTCTAAGGAAAGAGTGCAACGATGTGCCATGTTACAGTTTTCAGAATTTCATGAGAAGCTTGTTAATACTCTTT
GCAGAAAAACAGATGATGGCCAGATCACAGAACATGCCCAGAGCCTTGTGTTGGATACTCTCTGTTGGTTAGCTGGAGTTCATTCAAATG
GACCCGGAAGCTCAAAGGAAGGAAATGAGAACCTACTTTCAAAAACACGAAAATTTCTGTCAGACATCGTACGTGTTTGCTTCTTTGAGG
CAGGACGAAGTATAGCCCATAAGTGTGCCCGATTTCTAGCCTTGTGCATTAGTAATGGCAAATGTGACCCATGTCAACCAGCATTTGGAC
CTGTTCTGTTGAAGGCTTTACTTGATAATATGTCATTTTTACCTGCAGCAACAACTGGTGGTTCTGTCTATTGGTATTTTGTCTTACTGA
ATTATGTGAAAGATGAAGATCTGGCTGGATGCAGTACAGCTTGTGCATCTTTGCTTACTGCAGTGTCCAGACAGTTACAGGACAGGCTAA
CACCAATGGAGGCTTTACTTCAGACAAGATATGGATTATATAGCTCACCATTTGATCCAGTCCTCTTTGATTTGGAGATGAGTGGCTCTT
CTTGTAAAAATGTTTATAACAGCAGCATTGGTGTCCAGTCAGATGAAATTGATTTATCAGATGTCCTTTCAGGAAATGGAAAGGTCAGTA
GTTGCACAGCTGCTGAGGGTAGTTTCACATCTCTCACTGGACTTTTGGAAGTTGAACCTCTGCACTTTACTTGTGTGTCAACTAGTGATG
GAACCAGAATAGAAAGGGATGATGCAATGAGTTCCTTCGGGGTTACTCCTGCAGTAGGTGGACTATCATCTGGGACAGTTGGGGAAGCCT
CGACAGCCCTGAGTTCAGCAGCCCAGGTAGCTTTGCAGTCTCTCTCTCATGCAATGGCTTCAGCCGAGCAACAGCTACAGGTGCTGCAAG
AGAAACAGCAGCAGCTTTTGAAGCTTCAGCAACAGAAAGCAAAGCTGGAAGCCAAGTTACATCAGACAACAGCTGCAGCAGCTGCAGCAG
CATCAGCAGTAGGTCCTGTTCACAACTCTGTGCCTTCCAACCCAGTGGCTGCCCCTGGATTCTTCATTCATCCATCTGATGTTATTCCAC
CCACTCCAAAAACAACACCTCTTTTTATGACTCCACCACTCACTCCACCCAATGAAGCAGTTTCCGTTGTGATTAATGCCGAACTTGCAC
AGCTTTTCCCAGGCTCAGTCATTGATCCCCCAGCAGTCAATCTTGCTGCACATAACAAAAATTCCAACAAGTCCAGAATGAATCCACTTG
GTTCTGGTCTAGCCCTTGCAATTTCTCATGCTTCACATTTTCTTCAACCTCCGCCTCACCAGTCCATTATTATAGAGCGAATGCATTCAG
GAGCAAGAAGATTTGTGACCTTGGATTTTGGGAGGCCTATATTGTTGACTGATGTATTGATTCCCACTTGTGGAGACTTGGCCTCTTTGT
CAATTGACATTTGGACATTAGGAGAAGAGGTGGATGGAAGGCGGTTGGTAGTGGCAACTGATATAAGCACTCATTCACTAATTCTTCATG
ACTTAATACCACCTCCCGTGTGCAGATTCATGAAGATCACTGTTATTGGACGTTACGGGAGTACAAATGCCAGAGCCAAAATCCCATTAG
GATTTTACTATGGTCATACCTACATCTTGCCTTGGGAAAGTGAACTGAAGTTAATGCATGATCCTCTAAAGGGAGAGGGAGAATCTGCAA
ACCAGCCAGAAATTGACCAGCATTTAGCAATGATGGTTGCTTTGCAGGAGGATATACAGTGCAGGTATAACTTGGCTTGTCATCGTCTGG
AAACCCTTTTGCAAAGTATTGATCTTCCTCCTCTAAACAGTGCTAACAATGCACAGTACTTTTTACGAAAACCAGATAAGGCAGTTGAGG
AAGACAGTAGGGTTTTTTCTGCTTATCAAGATTGTATTCAGCTACAGCTTCAACTAAATTTGGCTCATAATGCAGTGCAGAGGCTCAAAG
TGGCGCTAGGTGCAAGCCGGAAGATGTTGAGTGAAACATCAAATCCAGAAGATTTAATTCAGACATCTTCCACAGAGCAGTTACGTACTA
TCATCAGATATTTACTGGACACTTTGCTCAGCCTGCTTCATGCTTCTAATGGACACTCTGTTCCTGCAGTTTTGCAGAGCACATTTCATG
CCCAGGCCTGTGAAGAGCTCTTTAAACACTTGTGCATCAGTGGAACCCCAAAGATACGGTTACATACTGGTCTTCTTCTTGTTCAACTGT
GTGGTGGTGAAAGGTGGTGGGGTCAATTTCTTTCTAATGTCCTTCAGGAATTGTACAATTCGGAACAGCTTCTCATCTTTCCACAGGATA
GGGTCTTCATGTTACTTTCCTGCATTGGTCAAAGATCACTTAGTAATAGTGGAGTATTAGAAAGCTTACTTAATCTCTTGGATAATTTAT
TGTCACCTCTTCAGCCACAGTTACCCATGCATAGGAGGACAGAAGGAGTACTAGATATTCCCATGATCAGTTGGGTTGTTATGCTGGTGT
CCAGGTTGCTGGATTATGTGGCAACTGTTGAAGATGAAGCAGCAGCTGCAAAGAAACCTTTGAATGGTAATCAGTGGAGTTTTATTAACA
ATAATCTACACACTCAGAGCTTAAATAGATCTTCTAAAGGCAGCAGTAGCCTTGATAGATTATATTCCAGAAAAATCAGAAAGCAGCTTG
TTCATCATAAACAGCAACTTAACCTACTAAAAGCAAAGCAGAAGGCATTGGTAGAACAGATGGAAAAAGAAAAAATACAAAGTAACAAAG
GATCATCATATAAACTCCTGGTAGAACAAGCAAAACTAAAGCAGGCCACTTCAAAGCACTTTAAGGATTTAATTCGTTTACGTCGGACAG
CAGAATGGTCCCGTTCTAATTTAGACACAGAAGTTACAACAGCAAAAGAAAGTCCTGAGATAGAACCACTTCCATTTACTCTGGCCCATG
AGCGTTGTATCTCAGTAGTCCAGAAACTTGTTCTGTTTCTTCTCTCCATGGACTTTACATGTCATGCAGATCTCTTATTGTTTGTTTGTA
AGGTTCTTGCACGCATTGCAAATGCCACGAGGCCAACTATTCATCTGTGTGAGATTGTGAACGAACCCCAGCTGGAAAGACTGCTGTTAC
TTTTGGTTGGAACTGACTTCAATAGAGGAGATATATCTTGGGGTGGTGCTTGGGCTCAGTATTCCTTAACTTGCATGCTACAAGATATTT
TAGCAGGAGAATTACTGGCTCCAGTAGCCGCAGAAGCCATGGAGGAAGGAACAGTGGGTGATGATGTAGGTGCGACAGCTGGTGACTCTG
ATGACTCCCTTCAACAGTCCTCAGTTCAGTTGCTGGAAACTATAGATGAACCTTTGACACATGACATAACAGGTGCACCTCCTCTGTCCT
CTTTGGAAAAAGATAAAGAAATTGACCTTGAGTTACTTCAGGATCTAATGGAAGTTGACATTGATCCTTTAGATATTGATTTGGAAAAGG
ACCCTCTTGCAGCCAAGGTTTTTAAGCCAATAAGCAGTACATGGTATGATTATTGGGGTGCTGATTATGGGACCTACAATTACAACCCTT
ACATTGGAGGTCTGGGAATTCCTGTAGCAAAGCCACCAGCAAACACGGAGAAGAACGGATCACAGACAGTTAGCGTTTCAGTCTCTCAGG
CCCTGGATGCTCGCCTAGAAGTTGGACTTGAACAGCAAGCAGAACTGATGTTGAAAATGATGTCTACTCTGGAGGCAGATTCCATTTTAC
AGGCATTAACAAATACATCTCCTACATTATCACAGTCTCCCACTGGAACAGATGATTCACTTCTAGGGGGTTTACAAGCAGCAAACCAAA
CCAGCCAGCTTATTATACAGTTATCATCTGTCCCAATGTTAAATGTTTGTTTCAACAAACTTTTTTCCATGCTTCAAGTCCATCATGTTC
AGTTGGAGTCACTTCTCCAATTGTGGCTCACACTGAGCCTGAATTCTAGTTCAACTGGAAACAAAGAAAATGGAGCAGACATATTTTTAT
ATAATGCTAATAGGATACCTGTTATTTCATTAAATCAAGCATCAATAACTAGCTTTCTCACAGTGTTAGCTTGGTATCCCAATACTTTGC
TCCGGACATGGTGCCTTGTGCTTCATAGCCTAACACTCATGACAAACATGCAGCTTAATTCTGGTTCCAGCAGTGCCATTGGAACTCAGG
AGAGTACTGCTCATTTGTTGGTTTCAGATCCAAACCTAATTCATGTATTAGTGAAATTTCTTTCTGGCACCAGTCCACATGGAACAAATC
AACACAGTCCACAGGTTGGTCCTACAGCTACACAAGCTATGCAAGAATTTCTTACTCGATTACAAGTGCATCTTTCTTCAACATGTCCTC
AGATATTCAGTGAATTTTTGCTCAAGCTAATTCATATACTTTCAACTGAAAGGGGTGCTTTCCAGACAGGCCAAGGACCTCTCGATGCCC
AAGTGAAGCTCTTAGAATTCACTCTGGAGCAGAATTTTGAAGTCGTTTCAGTTAGTACTATTTCTGCCGTGATAGAATCGGTTACATTTT
TAGTGCACCACTATATCACTTGCTCAGACAAAGTAATGTCAAGAAGTGGATCAGATAGCTCCGTGGGTGCTCGAGCATGCTTTGGGGGAC
TCTTTGCCAATCTTATTCGTCCGGGTGATGCAAAAGCAGTTTGTGGCGAAATGACAAGAGATCAACTCATGTTTGATTTGTTAAAACTTG
TTAACATTTTAGTGCAGCTGCCTCTTTCAGGCAATAGGGAATACAGTGCAAGAGTGTCTGTGACCACAAATACAACAGATAGTGTTTCAG
ATGAAGAAAAAGTCTCAGGAGGCAAAGATGGCAATGGAAGCAGTACCAGTGTTCAAGGATCGCCTGCATATGTTGCTGACTTAGTCTTAG
CCAACCAACAAATTATGAGCCAGATTTTGTCTGCTCTGGGCCTGTGTAATAGCAGTGCCATGGCAATGATAATTGGAGCAAGTGGATTAC
ATCTCACTAAACATGAAAACTTTCATGGTGGGTTGGATGCCATATCAGTTGGGGATGGATTATTTACCATACTGACAACCCTTAGTAAAA
AAGCTTCTACAGTCCACATGATGCTGCAGCCAATTTTAACATACATGGCCTGTGGATATATGGGCAGACAAGGCTCTCTTGCTACTTGCC
AGTTATCTGAGCCATTATTGTGGTTCATTTTGAGAGTATTGGATACTAGTGATGCCTTGAAAGCATTTCATGATATGGGTGGTGTTCAGC
TCATATGCAATAATATGGTTACTAGTACAAGGGCTATTGTGAACACTGCAAGAAGTATGGTATCAACTATTATGAAATTTCTTGACTCTG
GTCCAAATAAAGCTGTTGACAGCACATTGAAAACAAGAATACTAGCTTCTGAGCCTGACAATGCTGAAGGGATTCATAACTTTGCACCCC
TCGGTACAATCACATCTAGCAGTCCTACTGCCCAACCAGCTGAAGTGCTATTGCAGGCCACACCTCCTCACAGAAGAGCTCGCTCTGCTG
CTTGGTCCTACATCTTTCTTCCAGAGGAGGCTTGGTGTGACCTTACCATTCACCTTCCTGCAGCAGTGCTGCTTAAGGAGATACATATCC
AGCCTCATCTTGCATCTCTTGCAACCTGCCCTTCCTCAGTGTCTGTTGAAGTAAGTGCAGATGGGGTAAATATGCTACCTTTGTCCACTC
CTGTTGTCACAAGTGGCCTCACCTACATAAAAATTCAGCTTGTAAAAGCCGAAGTAGCTTCTGCTGTCTGCCTTAGACTACATCGTCCAC
GGGATGCCAGCACATTAGGCCTTTCACAAATTAAATTATTGGGGCTCACTGCTTTTGGTACCACCTCTTCTGCAACAGTTAATAATCCAT
TCCTTCCATCTGAAGATCAGGTATCCAAAACAAGTATTGGATGGTTACGGTTATTACATCATTGCCTTACTCACATAAGTGATCTAGAAG
GAATGATGGCAAGTGCAGCTGCACCTACTGCTAATCTGCTGCAGACTTGTGCGGCCTTATTGATGTCACCTTACTGTGGAATGCATTCAC
CCAACATCGAGGTTGTGCTTGTAAAGATAGGACTGCAGTCTACTAGAATTGGCCTGAAGCTCATAGACATTCTCCTGAGAAATTGTGCAG
CATCAGGCAGTGATCCTACAGATTTGAATAGTCCTTTACTTTTTGGAAGACTAAATGGACTCTCTTCTGACTCTACGATAGATATTCTTT
ACCAGCTTGGAACAACTCAGGATCCTGGTACAAAAGACAGAATTCAGGCCTTGTTAAAATGGGTTAGTGATTCTGCAAGAGTGGCTGCTA
TGAAGAGAAGTGGCAGGATGAACTACATGTGTCCTAACTCCTCAACAGTAGAGTATGGTCTTCTGATGCCATCTCCTTCTCATTTGCACT
GTGTAGCAGCCATTCTGTGGCATAGTTATGAGCTGCTTGTAGAATATGACTTACCAGCACTCCTGGACCAAGAGCTCTTTGAGTTACTTT
TTAATTGGTCCATGTCTCTTCCCTGCAATATGGTTTTGAAGAAAGCTGTTGACAGTCTACTTTGCTCAATGTGTCACGTACACCCAAACT
ATTTTTCTTTGCTCATGGGCTGGATGGGAATTACCCCTCCTCCAGTGCAATGTCATCATAGACTGTCCATGACAGATGATAGCAAAAAGC
AGGATCTTAGTTCATCTTTAACAGATGACTCTAAAAATGCACAAGCACCTCTCGCATTAACTGAATCACATTTGGCTACCCTTGCTTCCT
CTTCTCAATCTCCTGAAGCTATTAAACAATTACTAGACTCAGGTTTGCCTTCTCTTCTTGTGAGGAGTCTGGCTAGTTTCTGCTTTAGCC
ACATTTCTAGCTCAGAAAGCATTGCCCAGTCAATAGATATTTCCCAGGACAAACTCAGGCGCCATCATGTCCCACAACAATGTAATAAGA
TGCCTATCACAGCCGACCTAGTTGCTCCTATTCTTAGGTTTTTGACAGAAGTTGGCAATAGCCATATTATGAAAGATTGGCTTGGTGGTT
CTGAAGTCAATCCACTATGGACAGCACTTCTGTTTTTATTGTGTCACTCTGGGTCCACTTCTGGAAGCCATAATTTAGGTGCACAACAGA
CCAGTGCAAGATCAGCTTCTCTTTCTTCAGCTGCTACAACAGGACTGACTACTCAACAGCGCACAGCAATTGAGAATGCAACTGTTGCGT
TCTTTCTACAGTGCATTTCATGCCATCCTAATAATCAAAAGCTGATGGCACAGGTTCTTTGTGAACTATTTCAGACATCTCCTCAAAGAG
GGAACCTTCCAACATCTGGGAACATTTCAGGGTTTATACGAAGATTATTTTTACAGTTGATGCTGGAAGATGAGAAAGTGACAATGTTTC
TTCAGTCTCCATGTCCACTGTACAAAGGTAGAATTAATGCTACTAGCCACGTCATCCAGCATCCAATGTATGGAGCAGGCCACAAATTCC
GTACTCTTCATTTGCCAGTCTCAACAACATTATCAGATGTTCTTGACAGAGTGTCAGATACTCCAAGTATCACAGCTAAATTAATTAGTG
AACAAAAAGATGACAAAGAAAAGAAAAACCATGAAGAGAAAGAAAAAGTTAAAGCGGAAAATGGATTTCAAGACAATTACAGTGTTGTTG
TTGCCTCTGGGCTGAAGTCTCAATCTAAACGTGCTGTGTCAGCTACACCACCTCGCCCACCATCCAGGAGGGGGAGGACAATACCTGATA
AAATAGGAAGTACTTCAGGAGCAGAGGCTGCCAACAAAATAATTACTGTCCCAGTGTTTCACCTGTTTCACAAACTCTTGGCAGGCCAGC
CATTGCCAGCTGAAATGACACTTGCCCAGCTTTTAACTCTCCTATATGACCGAAAACTTCCTCAGGGTTACCGCTCAATAGATCTGACTG
TTAAATTGGGATCAAGAGTTATAACAGACCCCAGTCTATCAAAAACAGATTCTTATAAAAGACTACACCCTGAAAAAGATCATGGAGACT
TACTTGCTAGCTGTCCAGAAGATGAGGCTCTCACTCCAGGTGATGAATGCATGGATGGGATACTGGATGAATCTTTGCTTGAAACCTGTC
CAATTCAGTCACCATTACAAGTTTTTGCAGGAATGGGTGGACTGGCTCTTATTGCTGAAAGACTACCCATGCTATATCCAGAAGTAATTC
AACAGGTGAGTGCTCCAGTTGTAACATCTACCACTCAGGAAAAGCCGAAGGATAGCGATCAGTTTGAATGGGTGACCATTGAACAGTCAG
GGGAGTTAGTTTATGAAGCACCAGAAACTGTTGCGGCTGAACCTCCACCTATCAAGTCAGCAGTACAGACCATGTCTCCCATACCTGCCC
ATTCTTTGGCTGCTTTTGGATTATTTCTTCGTCTTCCGGGCTATGCGGAAGTGCTACTGAAAGAGAGAAAACATGCCCAGTGCCTTCTTC
GATTGGTATTGGGAGTGACAGATGATGGAGAAGGAAGTGCTTTGGGAAAAAGAACACGGTTCCAGGAAAATTATGTGGCACAACTGATTC
TAGATGTAAGAAGGGAAGGGGATGTCCTTTCAAATTGTGAATTCACTCCAGCACCCACTCCTCAGGAACATTTAACCAAGAATCTTGAGC
TCAATGATGACACCATTCTGAATGACATAAAGTTAGCAGATTGTGAACAGTTCCAGATGCCGGATCTGTGTGCTGAAGAGATCGCTATTA
TTCTTGGAATCTGCACTAATTTTCAAAAGAATAACCCAGTGCACACATTAACTGAAGTGGAGCTTCTGGCATTTACATCATGTTTGCTTT
CACAACCAAAGTTCTGGGCCATTCAGACATCAGCCTTGATCCTCCGGACAAAACTTGAGAAAGGAAGTACTCGCCGAGTGGAACGGGCAA
TGAGGCAGACACAGGCTCTTGCAGACCAATTTGAAGATAAAACTACATCTGTATTGGAACGCCTGAAGATTTTCTATTGCTGTCAAGTAC
CACCTCACTGGGCCATTCAGCGCCAACTTGCAAGTTTGCTCTTTGAGTTGGGATGTACCAGTTCAGCCCTTCAGATATTTGAAAAGCTAG
AAATGTGGGAAGATGTTGTCATTTGTTATGAAAGAGCCGGGCAGCACGGAAAGGCAGAAGAAATCCTTAGACAAGAGCTGGAGAAAAAAG
AAACGCCTAGTTTATACTGCTTGCTTGGAGATGTCCTCGGAGACCATTCTTGCTATGACAAGGCCTGGGAGTTGTCCCGGTACCGCAGTG
CTCGTGCTCAGCGCTCCAAAGCCCTCCTTCATCTTCGGAACAAGGAGTTTCAAGAGTGTGTAGAGTGCTTCGAACGCTCGGTTAAGATTA
ATCCCATGCAGCTCGGGGTGTGGTTTTCTCTCGGTTGTGCCTATTTGGCCTTGGAAGACTATCAAGGTTCAGCAAAGGCATTTCAGCGCT
GTGTGACTCTAGAACCCGATAATGCTGAAGCTTGGAACAATTTGTCAACTTCCTATATCCGATTAAAACAAAAAGTAAAAGCTTTTAGAA
CTTTACAAGAAGCTCTCAAGTGTAACTATGAACACTGGCAGATTTGGGAAAACTACATCCTCACCAGCACTGACGTTGGGGAATTTTCAG
AAGCCATTAAAGCTTATCACCGGCTCTTGGACTTACGTGACAAATACAAAGATGTTCAGGTCCTTAAAATTCTAGTCAGGGCAGTGATTG
ATGGGATGACTGATCGAAGTGGAGATGTTGCAACTGGCCTCAAAGGAAAGCTGCAGGAGTTATTTGGCAGAGTGACTTCAAGAGTGACAA
ATGATGGAGAAATCTGGAGGCTGTATGCCCACGTATATGGAAATGGGCAGAGTGAAAAGCCTGATGAAAATGAAAAGGCATTCCAGTGCC
TCTCAAAGGCATACAAGTGTGACACCCAGTCCAATTGTTGGGAGAAAGATATTACATCATTTAAGGAAGTTGTTCAAAGAGCCTTAGGAC
TTGCACATGTGGCCATAAAATGCAGTAAAAACAAATCCAGTTCCCAAGAAGCTGTACAAATGCTTTCTTCTGTTCGACTCAATTTACGGG
GCTTGTTATCTAAAGCAAAGCAACTTTTTACAGATGTGGCAACTGGAGAAATGTCCAGGGAATTAGCTGATGACATAACAGCTATGGACA
CCTTAGTGACAGAGCTCCAAGACCTAAGCAACCAGTTTCGAAATCAGTATTGATTCTGCTGGAAGCAGATTCTGGAAAAGGTGCTTTCAC

>9769_9769_5_BIRC6-TTC27_BIRC6_chr2_32768608_ENST00000421745_TTC27_chr2_32891702_ENST00000317907_length(amino acids)=4772AA_BP=0
MVTGGGAAPPGTVTEPLPSVIVLSAGRKMAAAAAAASGPGCSSAAGAGAAGVSEWLVLRDGCMHCDADGLHSLSYHPALNAILAVTSRGT
IKVIDGTSGATLQASALSAKPGGQVKCQYISAVDKVIFVDDYAVGCRKDLNGILLLDTALQTPVSKQDDVVQLELPVTEAQQLLSACLEK
VDISSTEGYDLFITQLKDGLKNTSHETAANHKVAKWATVTFHLPHHVLKSIASAIVNELKKINQNVAALPVASSVMDRLSYLLPSARPEL
GVGPGRSVDRSLMYSEANRRETFTSWPHVGYRWAQPDPMAQAGFYHQPASSGDDRAMCFTCSVCLVCWEPTDEPWSEHERHSPNCPFVKG
EHTQNVPLSVTLATSPAQFPCTDGTDRISCFGSGSCPHFLAAATKRGKICIWDVSKLMKVHLKFEINAYDPAIVQQLILSGDPSSGVDSR
RPTLAWLEDSSSCSDIPKLEGDSDDLLEDSDSEEHSRSDSVTGHTSQKEAMEVSLDITALSILQQPEKLQWEIVANVLEDTVKDLEELGA
NPCLTNSKSEKTKEKHQEQHNIPFPCLLAGGLLTYKSPATSPISSNSHRSLDGLSRTQGESISEQGSTDNESCTNSELNSPLVRRTLPVL
LLYSIKESDEKAGKIFSQMNNIMSKSLHDDGFTVPQIIEMELDSQEQLLLQDPPVTYIQQFADAAANLTSPDSEKWNSVFPKPGTLVQCL
RLPKFAEEENLCIDSITPCADGIHLLVGLRTCPVESLSAINQVEALNNLNKLNSALCNRRKGELESNLAVVNGANISVIQHESPADVQTP
LIIQPEQRNVSGGYLVLYKMNYATRIVTLEEEPIKIQHIKDPQDTITSLILLPPDILDNREDDCEEPIEDMQLTSKNGFEREKTSDISTL
GHLVITTQGGYVKILDLSNFEILAKVEPPKKEGTEEQDTFVSVIYCSGTDRLCACTKGGELHFLQIGGTCDDIDEADILVDGSLSKGIEP
SSEGSKPLSNPSSPGISGVDLLVDQPFTLEILTSLVELTRFETLTPRFSATVPPCWVEVQQEQQQRRHPQHLHQQHHGDAAQHTRTWKLQ
TDSNSWDEHVFELVLPKACMVGHVDFKFVLNSNITNIPQIQVTLLKNKAPGLGKVNALNIEVEQNGKPSLVDLNEEMQHMDVEESQCLRL
CPFLEDHKEDILCGPVWLASGLDLSGHAGMLTLTSPKLVKGMAGGKYRSFLIHVKAVNERGTEEICNGGMRPVVRLPSLKHQSNKGYSLA
SLLAKVAAGKEKSSNVKNENTSGTRKSENLRGCDLLQEVSVTIRRFKKTSISKERVQRCAMLQFSEFHEKLVNTLCRKTDDGQITEHAQS
LVLDTLCWLAGVHSNGPGSSKEGNENLLSKTRKFLSDIVRVCFFEAGRSIAHKCARFLALCISNGKCDPCQPAFGPVLLKALLDNMSFLP
AATTGGSVYWYFVLLNYVKDEDLAGCSTACASLLTAVSRQLQDRLTPMEALLQTRYGLYSSPFDPVLFDLEMSGSSCKNVYNSSIGVQSD
EIDLSDVLSGNGKVSSCTAAEGSFTSLTGLLEVEPLHFTCVSTSDGTRIERDDAMSSFGVTPAVGGLSSGTVGEASTALSSAAQVALQSL
SHAMASAEQQLQVLQEKQQQLLKLQQQKAKLEAKLHQTTAAAAAAASAVGPVHNSVPSNPVAAPGFFIHPSDVIPPTPKTTPLFMTPPLT
PPNEAVSVVINAELAQLFPGSVIDPPAVNLAAHNKNSNKSRMNPLGSGLALAISHASHFLQPPPHQSIIIERMHSGARRFVTLDFGRPIL
LTDVLIPTCGDLASLSIDIWTLGEEVDGRRLVVATDISTHSLILHDLIPPPVCRFMKITVIGRYGSTNARAKIPLGFYYGHTYILPWESE
LKLMHDPLKGEGESANQPEIDQHLAMMVALQEDIQCRYNLACHRLETLLQSIDLPPLNSANNAQYFLRKPDKAVEEDSRVFSAYQDCIQL
QLQLNLAHNAVQRLKVALGASRKMLSETSNPEDLIQTSSTEQLRTIIRYLLDTLLSLLHASNGHSVPAVLQSTFHAQACEELFKHLCISG
TPKIRLHTGLLLVQLCGGERWWGQFLSNVLQELYNSEQLLIFPQDRVFMLLSCIGQRSLSNSGVLESLLNLLDNLLSPLQPQLPMHRRTE
GVLDIPMISWVVMLVSRLLDYVATVEDEAAAAKKPLNGNQWSFINNNLHTQSLNRSSKGSSSLDRLYSRKIRKQLVHHKQQLNLLKAKQK
ALVEQMEKEKIQSNKGSSYKLLVEQAKLKQATSKHFKDLIRLRRTAEWSRSNLDTEVTTAKESPEIEPLPFTLAHERCISVVQKLVLFLL
SMDFTCHADLLLFVCKVLARIANATRPTIHLCEIVNEPQLERLLLLLVGTDFNRGDISWGGAWAQYSLTCMLQDILAGELLAPVAAEAME
EGTVGDDVGATAGDSDDSLQQSSVQLLETIDEPLTHDITGAPPLSSLEKDKEIDLELLQDLMEVDIDPLDIDLEKDPLAAKVFKPISSTW
YDYWGADYGTYNYNPYIGGLGIPVAKPPANTEKNGSQTVSVSVSQALDARLEVGLEQQAELMLKMMSTLEADSILQALTNTSPTLSQSPT
GTDDSLLGGLQAANQTSQLIIQLSSVPMLNVCFNKLFSMLQVHHVQLESLLQLWLTLSLNSSSTGNKENGADIFLYNANRIPVISLNQAS
ITSFLTVLAWYPNTLLRTWCLVLHSLTLMTNMQLNSGSSSAIGTQESTAHLLVSDPNLIHVLVKFLSGTSPHGTNQHSPQVGPTATQAMQ
EFLTRLQVHLSSTCPQIFSEFLLKLIHILSTERGAFQTGQGPLDAQVKLLEFTLEQNFEVVSVSTISAVIESVTFLVHHYITCSDKVMSR
SGSDSSVGARACFGGLFANLIRPGDAKAVCGEMTRDQLMFDLLKLVNILVQLPLSGNREYSARVSVTTNTTDSVSDEEKVSGGKDGNGSS
TSVQGSPAYVADLVLANQQIMSQILSALGLCNSSAMAMIIGASGLHLTKHENFHGGLDAISVGDGLFTILTTLSKKASTVHMMLQPILTY
MACGYMGRQGSLATCQLSEPLLWFILRVLDTSDALKAFHDMGGVQLICNNMVTSTRAIVNTARSMVSTIMKFLDSGPNKAVDSTLKTRIL
ASEPDNAEGIHNFAPLGTITSSSPTAQPAEVLLQATPPHRRARSAAWSYIFLPEEAWCDLTIHLPAAVLLKEIHIQPHLASLATCPSSVS
VEVSADGVNMLPLSTPVVTSGLTYIKIQLVKAEVASAVCLRLHRPRDASTLGLSQIKLLGLTAFGTTSSATVNNPFLPSEDQVSKTSIGW
LRLLHHCLTHISDLEGMMASAAAPTANLLQTCAALLMSPYCGMHSPNIEVVLVKIGLQSTRIGLKLIDILLRNCAASGSDPTDLNSPLLF
GRLNGLSSDSTIDILYQLGTTQDPGTKDRIQALLKWVSDSARVAAMKRSGRMNYMCPNSSTVEYGLLMPSPSHLHCVAAILWHSYELLVE
YDLPALLDQELFELLFNWSMSLPCNMVLKKAVDSLLCSMCHVHPNYFSLLMGWMGITPPPVQCHHRLSMTDDSKKQDLSSSLTDDSKNAQ
APLALTESHLATLASSSQSPEAIKQLLDSGLPSLLVRSLASFCFSHISSSESIAQSIDISQDKLRRHHVPQQCNKMPITADLVAPILRFL
TEVGNSHIMKDWLGGSEVNPLWTALLFLLCHSGSTSGSHNLGAQQTSARSASLSSAATTGLTTQQRTAIENATVAFFLQCISCHPNNQKL
MAQVLCELFQTSPQRGNLPTSGNISGFIRRLFLQLMLEDEKVTMFLQSPCPLYKGRINATSHVIQHPMYGAGHKFRTLHLPVSTTLSDVL
DRVSDTPSITAKLISEQKDDKEKKNHEEKEKVKAENGFQDNYSVVVASGLKSQSKRAVSATPPRPPSRRGRTIPDKIGSTSGAEAANKII
TVPVFHLFHKLLAGQPLPAEMTLAQLLTLLYDRKLPQGYRSIDLTVKLGSRVITDPSLSKTDSYKRLHPEKDHGDLLASCPEDEALTPGD
ECMDGILDESLLETCPIQSPLQVFAGMGGLALIAERLPMLYPEVIQQVSAPVVTSTTQEKPKDSDQFEWVTIEQSGELVYEAPETVAAEP
PPIKSAVQTMSPIPAHSLAAFGLFLRLPGYAEVLLKERKHAQCLLRLVLGVTDDGEGSALGKRTRFQENYVAQLILDVRREGDVLSNCEF
TPAPTPQEHLTKNLELNDDTILNDIKLADCEQFQMPDLCAEEIAIILGICTNFQKNNPVHTLTEVELLAFTSCLLSQPKFWAIQTSALIL
RTKLEKGSTRRVERAMRQTQALADQFEDKTTSVLERLKIFYCCQVPPHWAIQRQLASLLFELGCTSSALQIFEKLEMWEDVVICYERAGQ
HGKAEEILRQELEKKETPSLYCLLGDVLGDHSCYDKAWELSRYRSARAQRSKALLHLRNKEFQECVECFERSVKINPMQLGVWFSLGCAY
LALEDYQGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFSEAIKAYHRLLDLRDK
YKDVQVLKILVRAVIDGMTDRSGDVATGLKGKLQELFGRVTSRVTNDGEIWRLYAHVYGNGQSEKPDENEKAFQCLSKAYKCDTQSNCWE
KDITSFKEVVQRALGLAHVAIKCSKNKSSSQEAVQMLSSVRLNLRGLLSKAKQLFTDVATGEMSRELADDITAMDTLVTELQDLSNQFRN

--------------------------------------------------------------

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Fusion Gene PPI Analysis for BIRC6-TTC27


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for BIRC6-TTC27


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for BIRC6-TTC27


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneBIRC6C0006826Malignant Neoplasms1CTD_human
HgeneBIRC6C0027651Neoplasms1CTD_human
HgeneBIRC6C0086692Benign Neoplasm1CTD_human