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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:BAI2-SPOCD1 (FusionGDB2 ID:HG576TG90853)

Fusion Gene Summary for BAI2-SPOCD1

check button Fusion gene summary
Fusion gene informationFusion gene name: BAI2-SPOCD1
Fusion gene ID: hg576tg90853
HgeneTgene
Gene symbol

BAI2

SPOCD1

Gene ID

576

90853

Gene nameadhesion G protein-coupled receptor B2SPOC domain containing 1
SynonymsBAI2PPP1R146
Cytomap('ADGRB2','BAI2')('SPOCD1','SPOCD1')

1p35.2

1p35.2

Type of geneprotein-codingprotein-coding
Descriptionadhesion G protein-coupled receptor B2brain-specific angiogenesis inhibitor 2SPOC domain-containing protein 1protein phosphatase 1, regulatory subunit 146
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000257070, ENST00000373655, 
ENST00000373658, ENST00000398538, 
ENST00000398542, ENST00000398547, 
ENST00000398556, ENST00000527361, 
ENST00000440175, ENST00000465256, 
Fusion gene scores* DoF score3 X 3 X 3=275 X 5 X 4=100
# samples 57
** MAII scorelog2(5/27*10)=0.888968687611256
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
log2(7/100*10)=-0.514573172829758
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: BAI2 [Title/Abstract] AND SPOCD1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointADGRB2(32221600)-SPOCD1(32259836), # samples:1
BAI2(32221600)-SPOCD1(32259836), # samples:2
Anticipated loss of major functional domain due to fusion event.BAI2-SPOCD1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
BAI2-SPOCD1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
BAI2-SPOCD1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
BAI2-SPOCD1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
BAI2-SPOCD1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneBAI2

GO:0007186

G protein-coupled receptor signaling pathway

28891236

TgeneSPOCD1

GO:0010923

negative regulation of phosphatase activity

19389623


check buttonFusion gene breakpoints across BAI2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across SPOCD1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-BH-A0AV-01AADGRB2chr1

32221600

-SPOCD1chr1

32259836

-
ChimerDB4BRCATCGA-BH-A0AV-01ABAI2chr1

32221600

-SPOCD1chr1

32259836

-
ChimerDB4BRCATCGA-BH-A0AVBAI2chr1

32221599

-SPOCD1chr1

32259836

-


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Fusion Gene ORF analysis for BAI2-SPOCD1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000257070ENST00000360482BAI2chr1

32221600

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000257070ENST00000360482BAI2chr1

32221599

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000257070ENST00000373648BAI2chr1

32221600

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000257070ENST00000373648BAI2chr1

32221599

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000257070ENST00000533231BAI2chr1

32221600

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000257070ENST00000533231BAI2chr1

32221599

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000373655ENST00000360482BAI2chr1

32221600

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000373655ENST00000360482BAI2chr1

32221599

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000373655ENST00000373648BAI2chr1

32221600

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000373655ENST00000373648BAI2chr1

32221599

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000373655ENST00000533231BAI2chr1

32221600

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000373655ENST00000533231BAI2chr1

32221599

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000373658ENST00000360482BAI2chr1

32221600

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000373658ENST00000360482BAI2chr1

32221599

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000373658ENST00000373648BAI2chr1

32221600

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000373658ENST00000373648BAI2chr1

32221599

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000373658ENST00000533231BAI2chr1

32221600

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000373658ENST00000533231BAI2chr1

32221599

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000398538ENST00000360482BAI2chr1

32221600

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000398538ENST00000360482BAI2chr1

32221599

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000398538ENST00000373648BAI2chr1

32221600

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000398538ENST00000373648BAI2chr1

32221599

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000398538ENST00000533231BAI2chr1

32221600

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000398538ENST00000533231BAI2chr1

32221599

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000398542ENST00000360482BAI2chr1

32221600

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000398542ENST00000360482BAI2chr1

32221599

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000398542ENST00000373648BAI2chr1

32221600

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000398542ENST00000373648BAI2chr1

32221599

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000398542ENST00000533231BAI2chr1

32221600

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000398542ENST00000533231BAI2chr1

32221599

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000398547ENST00000360482BAI2chr1

32221600

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000398547ENST00000360482BAI2chr1

32221599

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000398547ENST00000373648BAI2chr1

32221600

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000398547ENST00000373648BAI2chr1

32221599

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000398547ENST00000533231BAI2chr1

32221600

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000398547ENST00000533231BAI2chr1

32221599

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000398556ENST00000360482BAI2chr1

32221600

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000398556ENST00000360482BAI2chr1

32221599

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000398556ENST00000373648BAI2chr1

32221600

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000398556ENST00000373648BAI2chr1

32221599

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000398556ENST00000533231BAI2chr1

32221600

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000398556ENST00000533231BAI2chr1

32221599

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000527361ENST00000360482BAI2chr1

32221600

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000527361ENST00000360482BAI2chr1

32221599

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000527361ENST00000373648BAI2chr1

32221600

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000527361ENST00000373648BAI2chr1

32221599

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000527361ENST00000533231BAI2chr1

32221600

-SPOCD1chr1

32259836

-
5CDS-3UTRENST00000527361ENST00000533231BAI2chr1

32221599

-SPOCD1chr1

32259836

-
Frame-shiftENST00000398542ENST00000257100BAI2chr1

32221600

-SPOCD1chr1

32259836

-
Frame-shiftENST00000398542ENST00000257100BAI2chr1

32221599

-SPOCD1chr1

32259836

-
Frame-shiftENST00000398547ENST00000257100BAI2chr1

32221600

-SPOCD1chr1

32259836

-
Frame-shiftENST00000398547ENST00000257100BAI2chr1

32221599

-SPOCD1chr1

32259836

-
Frame-shiftENST00000398556ENST00000257100BAI2chr1

32221600

-SPOCD1chr1

32259836

-
Frame-shiftENST00000398556ENST00000257100BAI2chr1

32221599

-SPOCD1chr1

32259836

-
Frame-shiftENST00000527361ENST00000257100BAI2chr1

32221600

-SPOCD1chr1

32259836

-
Frame-shiftENST00000527361ENST00000257100BAI2chr1

32221599

-SPOCD1chr1

32259836

-
In-frameENST00000257070ENST00000257100BAI2chr1

32221600

-SPOCD1chr1

32259836

-
In-frameENST00000257070ENST00000257100BAI2chr1

32221599

-SPOCD1chr1

32259836

-
In-frameENST00000373655ENST00000257100BAI2chr1

32221600

-SPOCD1chr1

32259836

-
In-frameENST00000373655ENST00000257100BAI2chr1

32221599

-SPOCD1chr1

32259836

-
In-frameENST00000373658ENST00000257100BAI2chr1

32221600

-SPOCD1chr1

32259836

-
In-frameENST00000373658ENST00000257100BAI2chr1

32221599

-SPOCD1chr1

32259836

-
In-frameENST00000398538ENST00000257100BAI2chr1

32221600

-SPOCD1chr1

32259836

-
In-frameENST00000398538ENST00000257100BAI2chr1

32221599

-SPOCD1chr1

32259836

-
intron-3CDSENST00000440175ENST00000257100BAI2chr1

32221600

-SPOCD1chr1

32259836

-
intron-3CDSENST00000440175ENST00000257100BAI2chr1

32221599

-SPOCD1chr1

32259836

-
intron-3CDSENST00000465256ENST00000257100BAI2chr1

32221600

-SPOCD1chr1

32259836

-
intron-3CDSENST00000465256ENST00000257100BAI2chr1

32221599

-SPOCD1chr1

32259836

-
intron-3UTRENST00000440175ENST00000360482BAI2chr1

32221600

-SPOCD1chr1

32259836

-
intron-3UTRENST00000440175ENST00000360482BAI2chr1

32221599

-SPOCD1chr1

32259836

-
intron-3UTRENST00000440175ENST00000373648BAI2chr1

32221600

-SPOCD1chr1

32259836

-
intron-3UTRENST00000440175ENST00000373648BAI2chr1

32221599

-SPOCD1chr1

32259836

-
intron-3UTRENST00000440175ENST00000533231BAI2chr1

32221600

-SPOCD1chr1

32259836

-
intron-3UTRENST00000440175ENST00000533231BAI2chr1

32221599

-SPOCD1chr1

32259836

-
intron-3UTRENST00000465256ENST00000360482BAI2chr1

32221600

-SPOCD1chr1

32259836

-
intron-3UTRENST00000465256ENST00000360482BAI2chr1

32221599

-SPOCD1chr1

32259836

-
intron-3UTRENST00000465256ENST00000373648BAI2chr1

32221600

-SPOCD1chr1

32259836

-
intron-3UTRENST00000465256ENST00000373648BAI2chr1

32221599

-SPOCD1chr1

32259836

-
intron-3UTRENST00000465256ENST00000533231BAI2chr1

32221600

-SPOCD1chr1

32259836

-
intron-3UTRENST00000465256ENST00000533231BAI2chr1

32221599

-SPOCD1chr1

32259836

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score

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Fusion Genomic Features for BAI2-SPOCD1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for BAI2-SPOCD1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:32221600/chr1:32259836)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBAI2chr1:32221599chr1:32259836ENST00000257070-432129_1342791552.0Compositional biasNote=Poly-Glu
HgeneBAI2chr1:32221599chr1:32259836ENST00000257070-432189_1922791552.0Compositional biasNote=Poly-Asn
HgeneBAI2chr1:32221599chr1:32259836ENST00000257070-432234_2372791552.0Compositional biasNote=Poly-Thr
HgeneBAI2chr1:32221599chr1:32259836ENST00000373655-433129_1342791585.0Compositional biasNote=Poly-Glu
HgeneBAI2chr1:32221599chr1:32259836ENST00000373655-433189_1922791585.0Compositional biasNote=Poly-Asn
HgeneBAI2chr1:32221599chr1:32259836ENST00000373655-433234_2372791585.0Compositional biasNote=Poly-Thr
HgeneBAI2chr1:32221599chr1:32259836ENST00000373658-433129_1342791586.0Compositional biasNote=Poly-Glu
HgeneBAI2chr1:32221599chr1:32259836ENST00000373658-433189_1922791586.0Compositional biasNote=Poly-Asn
HgeneBAI2chr1:32221599chr1:32259836ENST00000373658-433234_2372791586.0Compositional biasNote=Poly-Thr
HgeneBAI2chr1:32221599chr1:32259836ENST00000527361-230129_1342791552.0Compositional biasNote=Poly-Glu
HgeneBAI2chr1:32221599chr1:32259836ENST00000527361-230189_1922791552.0Compositional biasNote=Poly-Asn
HgeneBAI2chr1:32221599chr1:32259836ENST00000527361-230234_2372791552.0Compositional biasNote=Poly-Thr
HgeneBAI2chr1:32221600chr1:32259836ENST00000257070-432129_1342791552.0Compositional biasNote=Poly-Glu
HgeneBAI2chr1:32221600chr1:32259836ENST00000257070-432189_1922791552.0Compositional biasNote=Poly-Asn
HgeneBAI2chr1:32221600chr1:32259836ENST00000257070-432234_2372791552.0Compositional biasNote=Poly-Thr
HgeneBAI2chr1:32221600chr1:32259836ENST00000373655-433129_1342791585.0Compositional biasNote=Poly-Glu
HgeneBAI2chr1:32221600chr1:32259836ENST00000373655-433189_1922791585.0Compositional biasNote=Poly-Asn
HgeneBAI2chr1:32221600chr1:32259836ENST00000373655-433234_2372791585.0Compositional biasNote=Poly-Thr
HgeneBAI2chr1:32221600chr1:32259836ENST00000373658-433129_1342791586.0Compositional biasNote=Poly-Glu
HgeneBAI2chr1:32221600chr1:32259836ENST00000373658-433189_1922791586.0Compositional biasNote=Poly-Asn
HgeneBAI2chr1:32221600chr1:32259836ENST00000373658-433234_2372791586.0Compositional biasNote=Poly-Thr
HgeneBAI2chr1:32221600chr1:32259836ENST00000527361-230129_1342791552.0Compositional biasNote=Poly-Glu
HgeneBAI2chr1:32221600chr1:32259836ENST00000527361-230189_1922791552.0Compositional biasNote=Poly-Asn
HgeneBAI2chr1:32221600chr1:32259836ENST00000527361-230234_2372791552.0Compositional biasNote=Poly-Thr
TgeneSPOCD1chr1:32221599chr1:32259836ENST00000257100815608_728250697.0DomainTFIIS central
TgeneSPOCD1chr1:32221599chr1:32259836ENST00000257100815867_970250697.0DomainNote=SPOC
TgeneSPOCD1chr1:32221599chr1:32259836ENST00000360482916867_9707571217.0DomainNote=SPOC
TgeneSPOCD1chr1:32221599chr1:32259836ENST00000533231815867_9707571204.0DomainNote=SPOC
TgeneSPOCD1chr1:32221600chr1:32259836ENST00000257100815608_728250697.0DomainTFIIS central
TgeneSPOCD1chr1:32221600chr1:32259836ENST00000257100815867_970250697.0DomainNote=SPOC
TgeneSPOCD1chr1:32221600chr1:32259836ENST00000360482916867_9707571217.0DomainNote=SPOC
TgeneSPOCD1chr1:32221600chr1:32259836ENST00000533231815867_9707571204.0DomainNote=SPOC

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBAI2chr1:32221599chr1:32259836ENST00000257070-4321315_13182791552.0Compositional biasNote=Poly-Pro
HgeneBAI2chr1:32221599chr1:32259836ENST00000257070-4321364_13702791552.0Compositional biasNote=Poly-Gly
HgeneBAI2chr1:32221599chr1:32259836ENST00000257070-4321425_14302791552.0Compositional biasNote=Poly-Pro
HgeneBAI2chr1:32221599chr1:32259836ENST00000373655-4331315_13182791585.0Compositional biasNote=Poly-Pro
HgeneBAI2chr1:32221599chr1:32259836ENST00000373655-4331364_13702791585.0Compositional biasNote=Poly-Gly
HgeneBAI2chr1:32221599chr1:32259836ENST00000373655-4331425_14302791585.0Compositional biasNote=Poly-Pro
HgeneBAI2chr1:32221599chr1:32259836ENST00000373658-4331315_13182791586.0Compositional biasNote=Poly-Pro
HgeneBAI2chr1:32221599chr1:32259836ENST00000373658-4331364_13702791586.0Compositional biasNote=Poly-Gly
HgeneBAI2chr1:32221599chr1:32259836ENST00000373658-4331425_14302791586.0Compositional biasNote=Poly-Pro
HgeneBAI2chr1:32221599chr1:32259836ENST00000527361-2301315_13182791552.0Compositional biasNote=Poly-Pro
HgeneBAI2chr1:32221599chr1:32259836ENST00000527361-2301364_13702791552.0Compositional biasNote=Poly-Gly
HgeneBAI2chr1:32221599chr1:32259836ENST00000527361-2301425_14302791552.0Compositional biasNote=Poly-Pro
HgeneBAI2chr1:32221600chr1:32259836ENST00000257070-4321315_13182791552.0Compositional biasNote=Poly-Pro
HgeneBAI2chr1:32221600chr1:32259836ENST00000257070-4321364_13702791552.0Compositional biasNote=Poly-Gly
HgeneBAI2chr1:32221600chr1:32259836ENST00000257070-4321425_14302791552.0Compositional biasNote=Poly-Pro
HgeneBAI2chr1:32221600chr1:32259836ENST00000373655-4331315_13182791585.0Compositional biasNote=Poly-Pro
HgeneBAI2chr1:32221600chr1:32259836ENST00000373655-4331364_13702791585.0Compositional biasNote=Poly-Gly
HgeneBAI2chr1:32221600chr1:32259836ENST00000373655-4331425_14302791585.0Compositional biasNote=Poly-Pro
HgeneBAI2chr1:32221600chr1:32259836ENST00000373658-4331315_13182791586.0Compositional biasNote=Poly-Pro
HgeneBAI2chr1:32221600chr1:32259836ENST00000373658-4331364_13702791586.0Compositional biasNote=Poly-Gly
HgeneBAI2chr1:32221600chr1:32259836ENST00000373658-4331425_14302791586.0Compositional biasNote=Poly-Pro
HgeneBAI2chr1:32221600chr1:32259836ENST00000527361-2301315_13182791552.0Compositional biasNote=Poly-Pro
HgeneBAI2chr1:32221600chr1:32259836ENST00000527361-2301364_13702791552.0Compositional biasNote=Poly-Gly
HgeneBAI2chr1:32221600chr1:32259836ENST00000527361-2301425_14302791552.0Compositional biasNote=Poly-Pro
HgeneBAI2chr1:32221599chr1:32259836ENST00000257070-432309_3622791552.0DomainTSP type-1 1
HgeneBAI2chr1:32221599chr1:32259836ENST00000257070-432364_4172791552.0DomainTSP type-1 2
HgeneBAI2chr1:32221599chr1:32259836ENST00000257070-432419_4722791552.0DomainTSP type-1 3
HgeneBAI2chr1:32221599chr1:32259836ENST00000257070-432475_5282791552.0DomainTSP type-1 4
HgeneBAI2chr1:32221599chr1:32259836ENST00000257070-432871_9232791552.0DomainGPS
HgeneBAI2chr1:32221599chr1:32259836ENST00000373655-433309_3622791585.0DomainTSP type-1 1
HgeneBAI2chr1:32221599chr1:32259836ENST00000373655-433364_4172791585.0DomainTSP type-1 2
HgeneBAI2chr1:32221599chr1:32259836ENST00000373655-433419_4722791585.0DomainTSP type-1 3
HgeneBAI2chr1:32221599chr1:32259836ENST00000373655-433475_5282791585.0DomainTSP type-1 4
HgeneBAI2chr1:32221599chr1:32259836ENST00000373655-433871_9232791585.0DomainGPS
HgeneBAI2chr1:32221599chr1:32259836ENST00000373658-433309_3622791586.0DomainTSP type-1 1
HgeneBAI2chr1:32221599chr1:32259836ENST00000373658-433364_4172791586.0DomainTSP type-1 2
HgeneBAI2chr1:32221599chr1:32259836ENST00000373658-433419_4722791586.0DomainTSP type-1 3
HgeneBAI2chr1:32221599chr1:32259836ENST00000373658-433475_5282791586.0DomainTSP type-1 4
HgeneBAI2chr1:32221599chr1:32259836ENST00000373658-433871_9232791586.0DomainGPS
HgeneBAI2chr1:32221599chr1:32259836ENST00000527361-230309_3622791552.0DomainTSP type-1 1
HgeneBAI2chr1:32221599chr1:32259836ENST00000527361-230364_4172791552.0DomainTSP type-1 2
HgeneBAI2chr1:32221599chr1:32259836ENST00000527361-230419_4722791552.0DomainTSP type-1 3
HgeneBAI2chr1:32221599chr1:32259836ENST00000527361-230475_5282791552.0DomainTSP type-1 4
HgeneBAI2chr1:32221599chr1:32259836ENST00000527361-230871_9232791552.0DomainGPS
HgeneBAI2chr1:32221600chr1:32259836ENST00000257070-432309_3622791552.0DomainTSP type-1 1
HgeneBAI2chr1:32221600chr1:32259836ENST00000257070-432364_4172791552.0DomainTSP type-1 2
HgeneBAI2chr1:32221600chr1:32259836ENST00000257070-432419_4722791552.0DomainTSP type-1 3
HgeneBAI2chr1:32221600chr1:32259836ENST00000257070-432475_5282791552.0DomainTSP type-1 4
HgeneBAI2chr1:32221600chr1:32259836ENST00000257070-432871_9232791552.0DomainGPS
HgeneBAI2chr1:32221600chr1:32259836ENST00000373655-433309_3622791585.0DomainTSP type-1 1
HgeneBAI2chr1:32221600chr1:32259836ENST00000373655-433364_4172791585.0DomainTSP type-1 2
HgeneBAI2chr1:32221600chr1:32259836ENST00000373655-433419_4722791585.0DomainTSP type-1 3
HgeneBAI2chr1:32221600chr1:32259836ENST00000373655-433475_5282791585.0DomainTSP type-1 4
HgeneBAI2chr1:32221600chr1:32259836ENST00000373655-433871_9232791585.0DomainGPS
HgeneBAI2chr1:32221600chr1:32259836ENST00000373658-433309_3622791586.0DomainTSP type-1 1
HgeneBAI2chr1:32221600chr1:32259836ENST00000373658-433364_4172791586.0DomainTSP type-1 2
HgeneBAI2chr1:32221600chr1:32259836ENST00000373658-433419_4722791586.0DomainTSP type-1 3
HgeneBAI2chr1:32221600chr1:32259836ENST00000373658-433475_5282791586.0DomainTSP type-1 4
HgeneBAI2chr1:32221600chr1:32259836ENST00000373658-433871_9232791586.0DomainGPS
HgeneBAI2chr1:32221600chr1:32259836ENST00000527361-230309_3622791552.0DomainTSP type-1 1
HgeneBAI2chr1:32221600chr1:32259836ENST00000527361-230364_4172791552.0DomainTSP type-1 2
HgeneBAI2chr1:32221600chr1:32259836ENST00000527361-230419_4722791552.0DomainTSP type-1 3
HgeneBAI2chr1:32221600chr1:32259836ENST00000527361-230475_5282791552.0DomainTSP type-1 4
HgeneBAI2chr1:32221600chr1:32259836ENST00000527361-230871_9232791552.0DomainGPS
HgeneBAI2chr1:32221599chr1:32259836ENST00000257070-4321016_10362791552.0Topological domainCytoplasmic
HgeneBAI2chr1:32221599chr1:32259836ENST00000257070-4321058_10782791552.0Topological domainExtracellular
HgeneBAI2chr1:32221599chr1:32259836ENST00000257070-4321100_11212791552.0Topological domainCytoplasmic
HgeneBAI2chr1:32221599chr1:32259836ENST00000257070-4321143_11532791552.0Topological domainExtracellular
HgeneBAI2chr1:32221599chr1:32259836ENST00000257070-4321175_15852791552.0Topological domainCytoplasmic
HgeneBAI2chr1:32221599chr1:32259836ENST00000257070-43233_9362791552.0Topological domainExtracellular
HgeneBAI2chr1:32221599chr1:32259836ENST00000257070-432958_9652791552.0Topological domainCytoplasmic
HgeneBAI2chr1:32221599chr1:32259836ENST00000257070-432987_9942791552.0Topological domainExtracellular
HgeneBAI2chr1:32221599chr1:32259836ENST00000373655-4331016_10362791585.0Topological domainCytoplasmic
HgeneBAI2chr1:32221599chr1:32259836ENST00000373655-4331058_10782791585.0Topological domainExtracellular
HgeneBAI2chr1:32221599chr1:32259836ENST00000373655-4331100_11212791585.0Topological domainCytoplasmic
HgeneBAI2chr1:32221599chr1:32259836ENST00000373655-4331143_11532791585.0Topological domainExtracellular
HgeneBAI2chr1:32221599chr1:32259836ENST00000373655-4331175_15852791585.0Topological domainCytoplasmic
HgeneBAI2chr1:32221599chr1:32259836ENST00000373655-43333_9362791585.0Topological domainExtracellular
HgeneBAI2chr1:32221599chr1:32259836ENST00000373655-433958_9652791585.0Topological domainCytoplasmic
HgeneBAI2chr1:32221599chr1:32259836ENST00000373655-433987_9942791585.0Topological domainExtracellular
HgeneBAI2chr1:32221599chr1:32259836ENST00000373658-4331016_10362791586.0Topological domainCytoplasmic
HgeneBAI2chr1:32221599chr1:32259836ENST00000373658-4331058_10782791586.0Topological domainExtracellular
HgeneBAI2chr1:32221599chr1:32259836ENST00000373658-4331100_11212791586.0Topological domainCytoplasmic
HgeneBAI2chr1:32221599chr1:32259836ENST00000373658-4331143_11532791586.0Topological domainExtracellular
HgeneBAI2chr1:32221599chr1:32259836ENST00000373658-4331175_15852791586.0Topological domainCytoplasmic
HgeneBAI2chr1:32221599chr1:32259836ENST00000373658-43333_9362791586.0Topological domainExtracellular
HgeneBAI2chr1:32221599chr1:32259836ENST00000373658-433958_9652791586.0Topological domainCytoplasmic
HgeneBAI2chr1:32221599chr1:32259836ENST00000373658-433987_9942791586.0Topological domainExtracellular
HgeneBAI2chr1:32221599chr1:32259836ENST00000527361-2301016_10362791552.0Topological domainCytoplasmic
HgeneBAI2chr1:32221599chr1:32259836ENST00000527361-2301058_10782791552.0Topological domainExtracellular
HgeneBAI2chr1:32221599chr1:32259836ENST00000527361-2301100_11212791552.0Topological domainCytoplasmic
HgeneBAI2chr1:32221599chr1:32259836ENST00000527361-2301143_11532791552.0Topological domainExtracellular
HgeneBAI2chr1:32221599chr1:32259836ENST00000527361-2301175_15852791552.0Topological domainCytoplasmic
HgeneBAI2chr1:32221599chr1:32259836ENST00000527361-23033_9362791552.0Topological domainExtracellular
HgeneBAI2chr1:32221599chr1:32259836ENST00000527361-230958_9652791552.0Topological domainCytoplasmic
HgeneBAI2chr1:32221599chr1:32259836ENST00000527361-230987_9942791552.0Topological domainExtracellular
HgeneBAI2chr1:32221600chr1:32259836ENST00000257070-4321016_10362791552.0Topological domainCytoplasmic
HgeneBAI2chr1:32221600chr1:32259836ENST00000257070-4321058_10782791552.0Topological domainExtracellular
HgeneBAI2chr1:32221600chr1:32259836ENST00000257070-4321100_11212791552.0Topological domainCytoplasmic
HgeneBAI2chr1:32221600chr1:32259836ENST00000257070-4321143_11532791552.0Topological domainExtracellular
HgeneBAI2chr1:32221600chr1:32259836ENST00000257070-4321175_15852791552.0Topological domainCytoplasmic
HgeneBAI2chr1:32221600chr1:32259836ENST00000257070-43233_9362791552.0Topological domainExtracellular
HgeneBAI2chr1:32221600chr1:32259836ENST00000257070-432958_9652791552.0Topological domainCytoplasmic
HgeneBAI2chr1:32221600chr1:32259836ENST00000257070-432987_9942791552.0Topological domainExtracellular
HgeneBAI2chr1:32221600chr1:32259836ENST00000373655-4331016_10362791585.0Topological domainCytoplasmic
HgeneBAI2chr1:32221600chr1:32259836ENST00000373655-4331058_10782791585.0Topological domainExtracellular
HgeneBAI2chr1:32221600chr1:32259836ENST00000373655-4331100_11212791585.0Topological domainCytoplasmic
HgeneBAI2chr1:32221600chr1:32259836ENST00000373655-4331143_11532791585.0Topological domainExtracellular
HgeneBAI2chr1:32221600chr1:32259836ENST00000373655-4331175_15852791585.0Topological domainCytoplasmic
HgeneBAI2chr1:32221600chr1:32259836ENST00000373655-43333_9362791585.0Topological domainExtracellular
HgeneBAI2chr1:32221600chr1:32259836ENST00000373655-433958_9652791585.0Topological domainCytoplasmic
HgeneBAI2chr1:32221600chr1:32259836ENST00000373655-433987_9942791585.0Topological domainExtracellular
HgeneBAI2chr1:32221600chr1:32259836ENST00000373658-4331016_10362791586.0Topological domainCytoplasmic
HgeneBAI2chr1:32221600chr1:32259836ENST00000373658-4331058_10782791586.0Topological domainExtracellular
HgeneBAI2chr1:32221600chr1:32259836ENST00000373658-4331100_11212791586.0Topological domainCytoplasmic
HgeneBAI2chr1:32221600chr1:32259836ENST00000373658-4331143_11532791586.0Topological domainExtracellular
HgeneBAI2chr1:32221600chr1:32259836ENST00000373658-4331175_15852791586.0Topological domainCytoplasmic
HgeneBAI2chr1:32221600chr1:32259836ENST00000373658-43333_9362791586.0Topological domainExtracellular
HgeneBAI2chr1:32221600chr1:32259836ENST00000373658-433958_9652791586.0Topological domainCytoplasmic
HgeneBAI2chr1:32221600chr1:32259836ENST00000373658-433987_9942791586.0Topological domainExtracellular
HgeneBAI2chr1:32221600chr1:32259836ENST00000527361-2301016_10362791552.0Topological domainCytoplasmic
HgeneBAI2chr1:32221600chr1:32259836ENST00000527361-2301058_10782791552.0Topological domainExtracellular
HgeneBAI2chr1:32221600chr1:32259836ENST00000527361-2301100_11212791552.0Topological domainCytoplasmic
HgeneBAI2chr1:32221600chr1:32259836ENST00000527361-2301143_11532791552.0Topological domainExtracellular
HgeneBAI2chr1:32221600chr1:32259836ENST00000527361-2301175_15852791552.0Topological domainCytoplasmic
HgeneBAI2chr1:32221600chr1:32259836ENST00000527361-23033_9362791552.0Topological domainExtracellular
HgeneBAI2chr1:32221600chr1:32259836ENST00000527361-230958_9652791552.0Topological domainCytoplasmic
HgeneBAI2chr1:32221600chr1:32259836ENST00000527361-230987_9942791552.0Topological domainExtracellular
HgeneBAI2chr1:32221599chr1:32259836ENST00000257070-4321037_10572791552.0TransmembraneHelical%3B Name%3D4
HgeneBAI2chr1:32221599chr1:32259836ENST00000257070-4321079_10992791552.0TransmembraneHelical%3B Name%3D5
HgeneBAI2chr1:32221599chr1:32259836ENST00000257070-4321122_11422791552.0TransmembraneHelical%3B Name%3D6
HgeneBAI2chr1:32221599chr1:32259836ENST00000257070-4321154_11742791552.0TransmembraneHelical%3B Name%3D7
HgeneBAI2chr1:32221599chr1:32259836ENST00000257070-432937_9572791552.0TransmembraneHelical%3B Name%3D1
HgeneBAI2chr1:32221599chr1:32259836ENST00000257070-432966_9862791552.0TransmembraneHelical%3B Name%3D2
HgeneBAI2chr1:32221599chr1:32259836ENST00000257070-432995_10152791552.0TransmembraneHelical%3B Name%3D3
HgeneBAI2chr1:32221599chr1:32259836ENST00000373655-4331037_10572791585.0TransmembraneHelical%3B Name%3D4
HgeneBAI2chr1:32221599chr1:32259836ENST00000373655-4331079_10992791585.0TransmembraneHelical%3B Name%3D5
HgeneBAI2chr1:32221599chr1:32259836ENST00000373655-4331122_11422791585.0TransmembraneHelical%3B Name%3D6
HgeneBAI2chr1:32221599chr1:32259836ENST00000373655-4331154_11742791585.0TransmembraneHelical%3B Name%3D7
HgeneBAI2chr1:32221599chr1:32259836ENST00000373655-433937_9572791585.0TransmembraneHelical%3B Name%3D1
HgeneBAI2chr1:32221599chr1:32259836ENST00000373655-433966_9862791585.0TransmembraneHelical%3B Name%3D2
HgeneBAI2chr1:32221599chr1:32259836ENST00000373655-433995_10152791585.0TransmembraneHelical%3B Name%3D3
HgeneBAI2chr1:32221599chr1:32259836ENST00000373658-4331037_10572791586.0TransmembraneHelical%3B Name%3D4
HgeneBAI2chr1:32221599chr1:32259836ENST00000373658-4331079_10992791586.0TransmembraneHelical%3B Name%3D5
HgeneBAI2chr1:32221599chr1:32259836ENST00000373658-4331122_11422791586.0TransmembraneHelical%3B Name%3D6
HgeneBAI2chr1:32221599chr1:32259836ENST00000373658-4331154_11742791586.0TransmembraneHelical%3B Name%3D7
HgeneBAI2chr1:32221599chr1:32259836ENST00000373658-433937_9572791586.0TransmembraneHelical%3B Name%3D1
HgeneBAI2chr1:32221599chr1:32259836ENST00000373658-433966_9862791586.0TransmembraneHelical%3B Name%3D2
HgeneBAI2chr1:32221599chr1:32259836ENST00000373658-433995_10152791586.0TransmembraneHelical%3B Name%3D3
HgeneBAI2chr1:32221599chr1:32259836ENST00000527361-2301037_10572791552.0TransmembraneHelical%3B Name%3D4
HgeneBAI2chr1:32221599chr1:32259836ENST00000527361-2301079_10992791552.0TransmembraneHelical%3B Name%3D5
HgeneBAI2chr1:32221599chr1:32259836ENST00000527361-2301122_11422791552.0TransmembraneHelical%3B Name%3D6
HgeneBAI2chr1:32221599chr1:32259836ENST00000527361-2301154_11742791552.0TransmembraneHelical%3B Name%3D7
HgeneBAI2chr1:32221599chr1:32259836ENST00000527361-230937_9572791552.0TransmembraneHelical%3B Name%3D1
HgeneBAI2chr1:32221599chr1:32259836ENST00000527361-230966_9862791552.0TransmembraneHelical%3B Name%3D2
HgeneBAI2chr1:32221599chr1:32259836ENST00000527361-230995_10152791552.0TransmembraneHelical%3B Name%3D3
HgeneBAI2chr1:32221600chr1:32259836ENST00000257070-4321037_10572791552.0TransmembraneHelical%3B Name%3D4
HgeneBAI2chr1:32221600chr1:32259836ENST00000257070-4321079_10992791552.0TransmembraneHelical%3B Name%3D5
HgeneBAI2chr1:32221600chr1:32259836ENST00000257070-4321122_11422791552.0TransmembraneHelical%3B Name%3D6
HgeneBAI2chr1:32221600chr1:32259836ENST00000257070-4321154_11742791552.0TransmembraneHelical%3B Name%3D7
HgeneBAI2chr1:32221600chr1:32259836ENST00000257070-432937_9572791552.0TransmembraneHelical%3B Name%3D1
HgeneBAI2chr1:32221600chr1:32259836ENST00000257070-432966_9862791552.0TransmembraneHelical%3B Name%3D2
HgeneBAI2chr1:32221600chr1:32259836ENST00000257070-432995_10152791552.0TransmembraneHelical%3B Name%3D3
HgeneBAI2chr1:32221600chr1:32259836ENST00000373655-4331037_10572791585.0TransmembraneHelical%3B Name%3D4
HgeneBAI2chr1:32221600chr1:32259836ENST00000373655-4331079_10992791585.0TransmembraneHelical%3B Name%3D5
HgeneBAI2chr1:32221600chr1:32259836ENST00000373655-4331122_11422791585.0TransmembraneHelical%3B Name%3D6
HgeneBAI2chr1:32221600chr1:32259836ENST00000373655-4331154_11742791585.0TransmembraneHelical%3B Name%3D7
HgeneBAI2chr1:32221600chr1:32259836ENST00000373655-433937_9572791585.0TransmembraneHelical%3B Name%3D1
HgeneBAI2chr1:32221600chr1:32259836ENST00000373655-433966_9862791585.0TransmembraneHelical%3B Name%3D2
HgeneBAI2chr1:32221600chr1:32259836ENST00000373655-433995_10152791585.0TransmembraneHelical%3B Name%3D3
HgeneBAI2chr1:32221600chr1:32259836ENST00000373658-4331037_10572791586.0TransmembraneHelical%3B Name%3D4
HgeneBAI2chr1:32221600chr1:32259836ENST00000373658-4331079_10992791586.0TransmembraneHelical%3B Name%3D5
HgeneBAI2chr1:32221600chr1:32259836ENST00000373658-4331122_11422791586.0TransmembraneHelical%3B Name%3D6
HgeneBAI2chr1:32221600chr1:32259836ENST00000373658-4331154_11742791586.0TransmembraneHelical%3B Name%3D7
HgeneBAI2chr1:32221600chr1:32259836ENST00000373658-433937_9572791586.0TransmembraneHelical%3B Name%3D1
HgeneBAI2chr1:32221600chr1:32259836ENST00000373658-433966_9862791586.0TransmembraneHelical%3B Name%3D2
HgeneBAI2chr1:32221600chr1:32259836ENST00000373658-433995_10152791586.0TransmembraneHelical%3B Name%3D3
HgeneBAI2chr1:32221600chr1:32259836ENST00000527361-2301037_10572791552.0TransmembraneHelical%3B Name%3D4
HgeneBAI2chr1:32221600chr1:32259836ENST00000527361-2301079_10992791552.0TransmembraneHelical%3B Name%3D5
HgeneBAI2chr1:32221600chr1:32259836ENST00000527361-2301122_11422791552.0TransmembraneHelical%3B Name%3D6
HgeneBAI2chr1:32221600chr1:32259836ENST00000527361-2301154_11742791552.0TransmembraneHelical%3B Name%3D7
HgeneBAI2chr1:32221600chr1:32259836ENST00000527361-230937_9572791552.0TransmembraneHelical%3B Name%3D1
HgeneBAI2chr1:32221600chr1:32259836ENST00000527361-230966_9862791552.0TransmembraneHelical%3B Name%3D2
HgeneBAI2chr1:32221600chr1:32259836ENST00000527361-230995_10152791552.0TransmembraneHelical%3B Name%3D3
TgeneSPOCD1chr1:32221599chr1:32259836ENST00000360482916608_7287571217.0DomainTFIIS central
TgeneSPOCD1chr1:32221599chr1:32259836ENST00000533231815608_7287571204.0DomainTFIIS central
TgeneSPOCD1chr1:32221600chr1:32259836ENST00000360482916608_7287571217.0DomainTFIIS central
TgeneSPOCD1chr1:32221600chr1:32259836ENST00000533231815608_7287571204.0DomainTFIIS central


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Fusion Gene Sequence for BAI2-SPOCD1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

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Fusion Gene PPI Analysis for BAI2-SPOCD1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for BAI2-SPOCD1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for BAI2-SPOCD1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource