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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:FAM160B1-ADK (FusionGDB2 ID:HG57700TG132)

Fusion Gene Summary for FAM160B1-ADK

check button Fusion gene summary
Fusion gene informationFusion gene name: FAM160B1-ADK
Fusion gene ID: hg57700tg132
HgeneTgene
Gene symbol

FAM160B1

ADK

Gene ID

57700

132

Gene namefamily with sequence similarity 160 member B1adenosine kinase
SynonymsKIAA1600|bA106M7.3AK
Cytomap('FAM160B1')('ADK')

10q25.3

10q22.2|10q11-q24

Type of geneprotein-codingprotein-coding
Descriptionprotein FAM160B1adenosine kinaseadenosine 5'-phosphotransferasetesticular tissue protein Li 14
Modification date2020031320200313
UniProtAcc.

P55263

Ensembl transtripts involved in fusion geneENST00000369246, ENST00000369248, 
ENST00000369250, 
Fusion gene scores* DoF score7 X 5 X 5=17530 X 17 X 14=7140
# samples 764
** MAII scorelog2(7/175*10)=-1.32192809488736
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(64/7140*10)=-3.4797802640291
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: FAM160B1 [Title/Abstract] AND ADK [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointFAM160B1(116593161)-ADK(76349040), # samples:2
Anticipated loss of major functional domain due to fusion event.FAM160B1-ADK seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
FAM160B1-ADK seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across FAM160B1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across ADK (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PCPGTCGA-WB-A81S-01AFAM160B1chr10

116593161

-ADKchr10

76349040

+
ChimerDB4PCPGTCGA-WB-A81S-01AFAM160B1chr10

116593161

+ADKchr10

76349040

+


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Fusion Gene ORF analysis for FAM160B1-ADK

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000369246ENST00000467840FAM160B1chr10

116593161

+ADKchr10

76349040

+
5CDS-intronENST00000369248ENST00000467840FAM160B1chr10

116593161

+ADKchr10

76349040

+
5CDS-intronENST00000369250ENST00000467840FAM160B1chr10

116593161

+ADKchr10

76349040

+
In-frameENST00000369246ENST00000286621FAM160B1chr10

116593161

+ADKchr10

76349040

+
In-frameENST00000369246ENST00000372734FAM160B1chr10

116593161

+ADKchr10

76349040

+
In-frameENST00000369246ENST00000539909FAM160B1chr10

116593161

+ADKchr10

76349040

+
In-frameENST00000369246ENST00000541550FAM160B1chr10

116593161

+ADKchr10

76349040

+
In-frameENST00000369248ENST00000286621FAM160B1chr10

116593161

+ADKchr10

76349040

+
In-frameENST00000369248ENST00000372734FAM160B1chr10

116593161

+ADKchr10

76349040

+
In-frameENST00000369248ENST00000539909FAM160B1chr10

116593161

+ADKchr10

76349040

+
In-frameENST00000369248ENST00000541550FAM160B1chr10

116593161

+ADKchr10

76349040

+
In-frameENST00000369250ENST00000286621FAM160B1chr10

116593161

+ADKchr10

76349040

+
In-frameENST00000369250ENST00000372734FAM160B1chr10

116593161

+ADKchr10

76349040

+
In-frameENST00000369250ENST00000539909FAM160B1chr10

116593161

+ADKchr10

76349040

+
In-frameENST00000369250ENST00000541550FAM160B1chr10

116593161

+ADKchr10

76349040

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000369250FAM160B1chr10116593161+ENST00000539909ADKchr1076349040+124662944991315
ENST00000369250FAM160B1chr10116593161+ENST00000286621ADKchr1076349040+102262944991315
ENST00000369250FAM160B1chr10116593161+ENST00000372734ADKchr1076349040+185062944991315
ENST00000369250FAM160B1chr10116593161+ENST00000541550ADKchr1076349040+108562944991315
ENST00000369248FAM160B1chr10116593161+ENST00000539909ADKchr1076349040+124662944991315
ENST00000369248FAM160B1chr10116593161+ENST00000286621ADKchr1076349040+102262944991315
ENST00000369248FAM160B1chr10116593161+ENST00000372734ADKchr1076349040+185062944991315
ENST00000369248FAM160B1chr10116593161+ENST00000541550ADKchr1076349040+108562944991315
ENST00000369246FAM160B1chr10116593161+ENST00000539909ADKchr1076349040+111349618515165
ENST00000369246FAM160B1chr10116593161+ENST00000286621ADKchr1076349040+88949618515165
ENST00000369246FAM160B1chr10116593161+ENST00000372734ADKchr1076349040+171749618515165
ENST00000369246FAM160B1chr10116593161+ENST00000541550ADKchr1076349040+95249618515165

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000369250ENST00000539909FAM160B1chr10116593161+ADKchr1076349040+0.001517930.99848205
ENST00000369250ENST00000286621FAM160B1chr10116593161+ADKchr1076349040+0.0022754520.9977246
ENST00000369250ENST00000372734FAM160B1chr10116593161+ADKchr1076349040+0.000925080.99907494
ENST00000369250ENST00000541550FAM160B1chr10116593161+ADKchr1076349040+0.0026128120.99738723
ENST00000369248ENST00000539909FAM160B1chr10116593161+ADKchr1076349040+0.001517930.99848205
ENST00000369248ENST00000286621FAM160B1chr10116593161+ADKchr1076349040+0.0022754520.9977246
ENST00000369248ENST00000372734FAM160B1chr10116593161+ADKchr1076349040+0.000925080.99907494
ENST00000369248ENST00000541550FAM160B1chr10116593161+ADKchr1076349040+0.0026128120.99738723
ENST00000369246ENST00000539909FAM160B1chr10116593161+ADKchr1076349040+0.0403589570.95964104
ENST00000369246ENST00000286621FAM160B1chr10116593161+ADKchr1076349040+0.0295819960.97041804
ENST00000369246ENST00000372734FAM160B1chr10116593161+ADKchr1076349040+0.0391536650.9608463
ENST00000369246ENST00000541550FAM160B1chr10116593161+ADKchr1076349040+0.047106280.9528937

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Fusion Genomic Features for FAM160B1-ADK


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
FAM160B1chr10116593161+ADKchr1076349039+4.79E-060.99999523
FAM160B1chr10116593161+ADKchr1076349039+4.79E-060.99999523

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for FAM160B1-ADK


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:116593161/chr10:76349040)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ADK

P55263

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives. Serves as a potential regulator of concentrations of extracellular adenosine and intracellular adenine nucleotides.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneADKchr10:116593161chr10:76349040ENST000002866216118_16242363.0MotifNuclear localization signal
TgeneADKchr10:116593161chr10:76349040ENST000003727346118_16225346.0MotifNuclear localization signal
TgeneADKchr10:116593161chr10:76349040ENST000005399095108_16185306.0MotifNuclear localization signal
TgeneADKchr10:116593161chr10:76349040ENST000005415505108_16207328.0MotifNuclear localization signal


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Fusion Gene Sequence for FAM160B1-ADK


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>28619_28619_1_FAM160B1-ADK_FAM160B1_chr10_116593161_ENST00000369246_ADK_chr10_76349040_ENST00000286621_length(transcript)=889nt_BP=496nt
GAAGGAACCCGAGCCGGGCTGCCACCGTGTCCCAACCGGTGCCGCCGCCGGAGCTTCTCCGGGCCCCGAGTCCTCGCCGAACGCCCTCCT
CGCCGCCCGCCGCGTCCCGGCGCCCTCCGGAGCCGCCGAGCCGCCCGCGCACACCTGAAGCGGCCGGGCCAGGCCCTGCCTCGATCCTCA
GCTCGTCCTCCCCGCCCCGCACCGGCCTTCACTCTGGAGCGGCCCCGGCAGCCGCAGCAGGGGCGGCGGCGGCGGATCGAGGAGCTCTCC
AGGTCGTCCCGGGAGAGGCTGCTGCAGTCCCGGGACAGGATGTTCTCCAAGTTCACCTCCATCCTGCAGCACGCCGTGGAGGCGCTTGCA
CCTTCTCTTCCTTTACAAGAAGATTTTGTTTATCACTGGAAGGCAATTACCCATTACTACATAGAGACTTCAGGTAAGTTCCTGATCCAC
ACCATGTTCTTGGGCATTAGTACATGCATTAATGTCTTACGAATAAGAAGCTGCCACTTTTGCTAGAGAGCAAGGCTTTGAGACTAAAGA
CATTAAAGAGATAGCCAAAAAGACACAAGCCCTGCCAAAGATGAACTCAAAGAGGCAGCGAATCGTGATCTTCACCCAAGGGAGAGATGA
CACTATAATGGCTACAGAAAGTGAAGTCACTGCTTTTGCTGTCTTGGATCAAGACCAGAAAGAAATTATTGATACCAATGGAGCTGGAGA
TGCATTTGTTGGAGGTTTTCTGTCTCAACTGGTCTCTGACAAGCCTCTGACTGAATGTATCCGTGCTGGCCACTATGCAGCAAGCATCAT
AATTAGACGGACTGGCTGCACCTTTCCTGAGAAGCCAGACTTCCACTGATGGAAGAGCTGAAAACACAAGCCCAGGAGT

>28619_28619_1_FAM160B1-ADK_FAM160B1_chr10_116593161_ENST00000369246_ADK_chr10_76349040_ENST00000286621_length(amino acids)=165AA_BP=
MPPCPNRCRRRSFSGPRVLAERPPRRPPRPGALRSRRAARAHLKRPGQALPRSSARPPRPAPAFTLERPRQPQQGRRRRIEELSRSSRER
LLQSRDRMFSKFTSILQHAVEALAPSLPLQEDFVYHWKAITHYYIETSGKFLIHTMFLGISTCINVLRIRSCHFC

--------------------------------------------------------------
>28619_28619_2_FAM160B1-ADK_FAM160B1_chr10_116593161_ENST00000369246_ADK_chr10_76349040_ENST00000372734_length(transcript)=1717nt_BP=496nt
GAAGGAACCCGAGCCGGGCTGCCACCGTGTCCCAACCGGTGCCGCCGCCGGAGCTTCTCCGGGCCCCGAGTCCTCGCCGAACGCCCTCCT
CGCCGCCCGCCGCGTCCCGGCGCCCTCCGGAGCCGCCGAGCCGCCCGCGCACACCTGAAGCGGCCGGGCCAGGCCCTGCCTCGATCCTCA
GCTCGTCCTCCCCGCCCCGCACCGGCCTTCACTCTGGAGCGGCCCCGGCAGCCGCAGCAGGGGCGGCGGCGGCGGATCGAGGAGCTCTCC
AGGTCGTCCCGGGAGAGGCTGCTGCAGTCCCGGGACAGGATGTTCTCCAAGTTCACCTCCATCCTGCAGCACGCCGTGGAGGCGCTTGCA
CCTTCTCTTCCTTTACAAGAAGATTTTGTTTATCACTGGAAGGCAATTACCCATTACTACATAGAGACTTCAGGTAAGTTCCTGATCCAC
ACCATGTTCTTGGGCATTAGTACATGCATTAATGTCTTACGAATAAGAAGCTGCCACTTTTGCTAGAGAGCAAGGCTTTGAGACTAAAGA
CATTAAAGAGATAGCCAAAAAGACACAAGCCCTGCCAAAGATGAACTCAAAGAGGCAGCGAATCGTGATCTTCACCCAAGGGAGAGATGA
CACTATAATGGCTACAGAAAGTGAAGTCACTGCTTTTGCTGTCTTGGATCAAGACCAGAAAGAAATTATTGATACCAATGGAGCTGGAGA
TGCATTTGTTGGAGGTTTTCTGTCTCAACTGGTCTCTGACAAGCCTCTGACTGAATGTATCCGTGCTGGCCACTATGCAGCAAGCATCAT
AATTAGACGGACTGGCTGCACCTTTCCTGAGAAGCCAGACTTCCACTGATGGAAGAGCTGAAAACACAAGCCCAGGAGTGCAGACACTGC
CCTAATTGCTTCCTGAGAATTCCCATATTAATAAAGAAGAAAATTATCTGCCATTTTTTCCTACTATAATAATGCTGAATCTTAATTTAG
AGGGTACAAGGGTATGGTAATGCTTGTAGAATCTTTATTATCTCAACAATCTAAAAAATGATGTTTATTTCCATAGTTTGATAGTGCCAC
TTAAATGCCAATTAAACAAGAATATAACATTTCAATAGAAATTTTTATTTCATTTTCAATTACTTTGTAAATTCGTGTGTATTTAGTACA
CTGATTTGTTTTTTTACATTTCTGCTTTGAATGCAGATGCAATTTAATATAATAGATTTTTTAATGAATTAATCTTAACATAGTAATCTT
TAGCTTTTTATACAAATATATTTAATTTAGGAGTATATGTGTGTCTATACACACACATACATAAATATACCACATATACACCTGATAGTC
AAATAAGGTACAGAAATTTTATCTTGTCAATTATGCCAAATAATCTCTTTAATGTGCACTCAAACATGTAATAAACTTTGGATAATTAAA
TAATGTGCCAAATTTAAGTTGTACCACAATATTCAAATCATAGTCTTATGGAACTCTGTAATTGGACACAAACAAAAACTTGTCATATAG
GAATTTTTTTCTGTCTTTTCCCTGTGTACAGCAAACTGAGGAAGAAAGATCATTATTTAATACTGGGCCCTGAAATGACACCCAATTTGT
TAATGGAATTATGAAGAACAGCAATATAATACACTGAAGAATAACTTAGTATCAGAGACCAATAAATCACTTTTTTAAGGATGACAAAAT
GGTATAA

>28619_28619_2_FAM160B1-ADK_FAM160B1_chr10_116593161_ENST00000369246_ADK_chr10_76349040_ENST00000372734_length(amino acids)=165AA_BP=
MPPCPNRCRRRSFSGPRVLAERPPRRPPRPGALRSRRAARAHLKRPGQALPRSSARPPRPAPAFTLERPRQPQQGRRRRIEELSRSSRER
LLQSRDRMFSKFTSILQHAVEALAPSLPLQEDFVYHWKAITHYYIETSGKFLIHTMFLGISTCINVLRIRSCHFC

--------------------------------------------------------------
>28619_28619_3_FAM160B1-ADK_FAM160B1_chr10_116593161_ENST00000369246_ADK_chr10_76349040_ENST00000539909_length(transcript)=1113nt_BP=496nt
GAAGGAACCCGAGCCGGGCTGCCACCGTGTCCCAACCGGTGCCGCCGCCGGAGCTTCTCCGGGCCCCGAGTCCTCGCCGAACGCCCTCCT
CGCCGCCCGCCGCGTCCCGGCGCCCTCCGGAGCCGCCGAGCCGCCCGCGCACACCTGAAGCGGCCGGGCCAGGCCCTGCCTCGATCCTCA
GCTCGTCCTCCCCGCCCCGCACCGGCCTTCACTCTGGAGCGGCCCCGGCAGCCGCAGCAGGGGCGGCGGCGGCGGATCGAGGAGCTCTCC
AGGTCGTCCCGGGAGAGGCTGCTGCAGTCCCGGGACAGGATGTTCTCCAAGTTCACCTCCATCCTGCAGCACGCCGTGGAGGCGCTTGCA
CCTTCTCTTCCTTTACAAGAAGATTTTGTTTATCACTGGAAGGCAATTACCCATTACTACATAGAGACTTCAGGTAAGTTCCTGATCCAC
ACCATGTTCTTGGGCATTAGTACATGCATTAATGTCTTACGAATAAGAAGCTGCCACTTTTGCTAGAGAGCAAGGCTTTGAGACTAAAGA
CATTAAAGAGATAGCCAAAAAGACACAAGCCCTGCCAAAGATGAACTCAAAGAGGCAGCGAATCGTGATCTTCACCCAAGGGAGAGATGA
CACTATAATGGCTACAGAAAGTGAAGTCACTGCTTTTGCTGTCTTGGATCAAGACCAGAAAGAAATTATTGATACCAATGGAGCTGGAGA
TGCATTTGTTGGAGGTTTTCTGTCTCAACTGGTCTCTGACAAGCCTCTGACTGAATGTATCCGTGCTGGCCACTATGCAGCAAGCATCAT
AATTAGACGGACTGGCTGCACCTTTCCTGAGAAGCCAGACTTCCACTGATGGAAGAGCTGAAAACACAAGCCCAGGAGTGCAGACACTGC
CCTAATTGCTTCCTGAGAATTCCCATATTAATAAAGAAGAAAATTATCTGCCATTTTTTCCTACTATAATAATGCTGAATCTTAATTTAG
AGGGTACAAGGGTATGGTAATGCTTGTAGAATCTTTATTATCTCAACAATCTAAAAAATGATGTTTATTTCCATAGTTTGATAGTGCCAC
TTAAATGCCAATTAAACAAGAATATAACATTTC

>28619_28619_3_FAM160B1-ADK_FAM160B1_chr10_116593161_ENST00000369246_ADK_chr10_76349040_ENST00000539909_length(amino acids)=165AA_BP=
MPPCPNRCRRRSFSGPRVLAERPPRRPPRPGALRSRRAARAHLKRPGQALPRSSARPPRPAPAFTLERPRQPQQGRRRRIEELSRSSRER
LLQSRDRMFSKFTSILQHAVEALAPSLPLQEDFVYHWKAITHYYIETSGKFLIHTMFLGISTCINVLRIRSCHFC

--------------------------------------------------------------
>28619_28619_4_FAM160B1-ADK_FAM160B1_chr10_116593161_ENST00000369246_ADK_chr10_76349040_ENST00000541550_length(transcript)=952nt_BP=496nt
GAAGGAACCCGAGCCGGGCTGCCACCGTGTCCCAACCGGTGCCGCCGCCGGAGCTTCTCCGGGCCCCGAGTCCTCGCCGAACGCCCTCCT
CGCCGCCCGCCGCGTCCCGGCGCCCTCCGGAGCCGCCGAGCCGCCCGCGCACACCTGAAGCGGCCGGGCCAGGCCCTGCCTCGATCCTCA
GCTCGTCCTCCCCGCCCCGCACCGGCCTTCACTCTGGAGCGGCCCCGGCAGCCGCAGCAGGGGCGGCGGCGGCGGATCGAGGAGCTCTCC
AGGTCGTCCCGGGAGAGGCTGCTGCAGTCCCGGGACAGGATGTTCTCCAAGTTCACCTCCATCCTGCAGCACGCCGTGGAGGCGCTTGCA
CCTTCTCTTCCTTTACAAGAAGATTTTGTTTATCACTGGAAGGCAATTACCCATTACTACATAGAGACTTCAGGTAAGTTCCTGATCCAC
ACCATGTTCTTGGGCATTAGTACATGCATTAATGTCTTACGAATAAGAAGCTGCCACTTTTGCTAGAGAGCAAGGCTTTGAGACTAAAGA
CATTAAAGAGATAGCCAAAAAGACACAAGCCCTGCCAAAGATGAACTCAAAGAGGCAGCGAATCGTGATCTTCACCCAAGGGAGAGATGA
CACTATAATGGCTACAGAAAGTGAAGTCACTGCTTTTGCTGTCTTGGATCAAGACCAGAAAGAAATTATTGATACCAATGGAGCTGGAGA
TGCATTTGTTGGAGGTTTTCTGTCTCAACTGGTCTCTGACAAGCCTCTGACTGAATGTATCCGTGCTGGCCACTATGCAGCAAGCATCAT
AATTAGACGGACTGGCTGCACCTTTCCTGAGAAGCCAGACTTCCACTGATGGAAGAGCTGAAAACACAAGCCCAGGAGTGCAGACACTGC
CCTAATTGCTTCCTGAGAATTCCCATATTAATAAAGAAGAAAATTATCTGCC

>28619_28619_4_FAM160B1-ADK_FAM160B1_chr10_116593161_ENST00000369246_ADK_chr10_76349040_ENST00000541550_length(amino acids)=165AA_BP=
MPPCPNRCRRRSFSGPRVLAERPPRRPPRPGALRSRRAARAHLKRPGQALPRSSARPPRPAPAFTLERPRQPQQGRRRRIEELSRSSRER
LLQSRDRMFSKFTSILQHAVEALAPSLPLQEDFVYHWKAITHYYIETSGKFLIHTMFLGISTCINVLRIRSCHFC

--------------------------------------------------------------
>28619_28619_5_FAM160B1-ADK_FAM160B1_chr10_116593161_ENST00000369248_ADK_chr10_76349040_ENST00000286621_length(transcript)=1022nt_BP=629nt
GCAGGCCGCGGCGGGCAGAGCGGGGGGAAGGAACCCGAGCCGGGCTGCCACCGTGTCCCAACCGGTGCCGCCGCCGGAGCTTCTCCGGGC
CCCGAGTCCTCGCCGAACGCCCTCCTCGCCGCCCGCCGCGTCCCGGCGCCCTCCGGAGCCGCCGAGCCGCCCGCGCACACCTGAAGCGGC
CGGGCCAGGCCCTGCCTCGATCCTCAGCTCGTCCTCCCCGCCCCGCACCGGCCTTCACTCTGGAGCGGCCCCGGCAGCCGCAGCAGGGGC
GGCGGCGGCGGATCGAGGAGCTCTCCAGGTCGTCCCGGGAGAGGCTGCTGCAGTCCCGGGACAGGATGTTCTCCAAGTTCACCTCCATCC
TGCAGCACGCCGTGGAGGCGCTTGCACCTTCTCTTCCTTTACAAGAAGATTTTGTTTATCACTGGAAGGCAATTACCCATTACTACATAG
AGACTTCAGATGATAAAGCCCCAGTGACCGATACAAATATTCCATCGCATCTGGAACAGATGTTAGATATACTGGTTCAAGAAGAAAATG
AACGGGAATCTGGAGAGACAGGGCCATGTATGGAATATTTGCTTCATCACAAGATCTTGGAAACATTATATACCTTGGGGAAAGCTGATG
AAGCTGCCACTTTTGCTAGAGAGCAAGGCTTTGAGACTAAAGACATTAAAGAGATAGCCAAAAAGACACAAGCCCTGCCAAAGATGAACT
CAAAGAGGCAGCGAATCGTGATCTTCACCCAAGGGAGAGATGACACTATAATGGCTACAGAAAGTGAAGTCACTGCTTTTGCTGTCTTGG
ATCAAGACCAGAAAGAAATTATTGATACCAATGGAGCTGGAGATGCATTTGTTGGAGGTTTTCTGTCTCAACTGGTCTCTGACAAGCCTC
TGACTGAATGTATCCGTGCTGGCCACTATGCAGCAAGCATCATAATTAGACGGACTGGCTGCACCTTTCCTGAGAAGCCAGACTTCCACT
GATGGAAGAGCTGAAAACACAAGCCCAGGAGT

>28619_28619_5_FAM160B1-ADK_FAM160B1_chr10_116593161_ENST00000369248_ADK_chr10_76349040_ENST00000286621_length(amino acids)=315AA_BP=195
MPPCPNRCRRRSFSGPRVLAERPPRRPPRPGALRSRRAARAHLKRPGQALPRSSARPPRPAPAFTLERPRQPQQGRRRRIEELSRSSRER
LLQSRDRMFSKFTSILQHAVEALAPSLPLQEDFVYHWKAITHYYIETSDDKAPVTDTNIPSHLEQMLDILVQEENERESGETGPCMEYLL
HHKILETLYTLGKADEAATFAREQGFETKDIKEIAKKTQALPKMNSKRQRIVIFTQGRDDTIMATESEVTAFAVLDQDQKEIIDTNGAGD
AFVGGFLSQLVSDKPLTECIRAGHYAASIIIRRTGCTFPEKPDFH

--------------------------------------------------------------
>28619_28619_6_FAM160B1-ADK_FAM160B1_chr10_116593161_ENST00000369248_ADK_chr10_76349040_ENST00000372734_length(transcript)=1850nt_BP=629nt
GCAGGCCGCGGCGGGCAGAGCGGGGGGAAGGAACCCGAGCCGGGCTGCCACCGTGTCCCAACCGGTGCCGCCGCCGGAGCTTCTCCGGGC
CCCGAGTCCTCGCCGAACGCCCTCCTCGCCGCCCGCCGCGTCCCGGCGCCCTCCGGAGCCGCCGAGCCGCCCGCGCACACCTGAAGCGGC
CGGGCCAGGCCCTGCCTCGATCCTCAGCTCGTCCTCCCCGCCCCGCACCGGCCTTCACTCTGGAGCGGCCCCGGCAGCCGCAGCAGGGGC
GGCGGCGGCGGATCGAGGAGCTCTCCAGGTCGTCCCGGGAGAGGCTGCTGCAGTCCCGGGACAGGATGTTCTCCAAGTTCACCTCCATCC
TGCAGCACGCCGTGGAGGCGCTTGCACCTTCTCTTCCTTTACAAGAAGATTTTGTTTATCACTGGAAGGCAATTACCCATTACTACATAG
AGACTTCAGATGATAAAGCCCCAGTGACCGATACAAATATTCCATCGCATCTGGAACAGATGTTAGATATACTGGTTCAAGAAGAAAATG
AACGGGAATCTGGAGAGACAGGGCCATGTATGGAATATTTGCTTCATCACAAGATCTTGGAAACATTATATACCTTGGGGAAAGCTGATG
AAGCTGCCACTTTTGCTAGAGAGCAAGGCTTTGAGACTAAAGACATTAAAGAGATAGCCAAAAAGACACAAGCCCTGCCAAAGATGAACT
CAAAGAGGCAGCGAATCGTGATCTTCACCCAAGGGAGAGATGACACTATAATGGCTACAGAAAGTGAAGTCACTGCTTTTGCTGTCTTGG
ATCAAGACCAGAAAGAAATTATTGATACCAATGGAGCTGGAGATGCATTTGTTGGAGGTTTTCTGTCTCAACTGGTCTCTGACAAGCCTC
TGACTGAATGTATCCGTGCTGGCCACTATGCAGCAAGCATCATAATTAGACGGACTGGCTGCACCTTTCCTGAGAAGCCAGACTTCCACT
GATGGAAGAGCTGAAAACACAAGCCCAGGAGTGCAGACACTGCCCTAATTGCTTCCTGAGAATTCCCATATTAATAAAGAAGAAAATTAT
CTGCCATTTTTTCCTACTATAATAATGCTGAATCTTAATTTAGAGGGTACAAGGGTATGGTAATGCTTGTAGAATCTTTATTATCTCAAC
AATCTAAAAAATGATGTTTATTTCCATAGTTTGATAGTGCCACTTAAATGCCAATTAAACAAGAATATAACATTTCAATAGAAATTTTTA
TTTCATTTTCAATTACTTTGTAAATTCGTGTGTATTTAGTACACTGATTTGTTTTTTTACATTTCTGCTTTGAATGCAGATGCAATTTAA
TATAATAGATTTTTTAATGAATTAATCTTAACATAGTAATCTTTAGCTTTTTATACAAATATATTTAATTTAGGAGTATATGTGTGTCTA
TACACACACATACATAAATATACCACATATACACCTGATAGTCAAATAAGGTACAGAAATTTTATCTTGTCAATTATGCCAAATAATCTC
TTTAATGTGCACTCAAACATGTAATAAACTTTGGATAATTAAATAATGTGCCAAATTTAAGTTGTACCACAATATTCAAATCATAGTCTT
ATGGAACTCTGTAATTGGACACAAACAAAAACTTGTCATATAGGAATTTTTTTCTGTCTTTTCCCTGTGTACAGCAAACTGAGGAAGAAA
GATCATTATTTAATACTGGGCCCTGAAATGACACCCAATTTGTTAATGGAATTATGAAGAACAGCAATATAATACACTGAAGAATAACTT
AGTATCAGAGACCAATAAATCACTTTTTTAAGGATGACAAAATGGTATAA

>28619_28619_6_FAM160B1-ADK_FAM160B1_chr10_116593161_ENST00000369248_ADK_chr10_76349040_ENST00000372734_length(amino acids)=315AA_BP=195
MPPCPNRCRRRSFSGPRVLAERPPRRPPRPGALRSRRAARAHLKRPGQALPRSSARPPRPAPAFTLERPRQPQQGRRRRIEELSRSSRER
LLQSRDRMFSKFTSILQHAVEALAPSLPLQEDFVYHWKAITHYYIETSDDKAPVTDTNIPSHLEQMLDILVQEENERESGETGPCMEYLL
HHKILETLYTLGKADEAATFAREQGFETKDIKEIAKKTQALPKMNSKRQRIVIFTQGRDDTIMATESEVTAFAVLDQDQKEIIDTNGAGD
AFVGGFLSQLVSDKPLTECIRAGHYAASIIIRRTGCTFPEKPDFH

--------------------------------------------------------------
>28619_28619_7_FAM160B1-ADK_FAM160B1_chr10_116593161_ENST00000369248_ADK_chr10_76349040_ENST00000539909_length(transcript)=1246nt_BP=629nt
GCAGGCCGCGGCGGGCAGAGCGGGGGGAAGGAACCCGAGCCGGGCTGCCACCGTGTCCCAACCGGTGCCGCCGCCGGAGCTTCTCCGGGC
CCCGAGTCCTCGCCGAACGCCCTCCTCGCCGCCCGCCGCGTCCCGGCGCCCTCCGGAGCCGCCGAGCCGCCCGCGCACACCTGAAGCGGC
CGGGCCAGGCCCTGCCTCGATCCTCAGCTCGTCCTCCCCGCCCCGCACCGGCCTTCACTCTGGAGCGGCCCCGGCAGCCGCAGCAGGGGC
GGCGGCGGCGGATCGAGGAGCTCTCCAGGTCGTCCCGGGAGAGGCTGCTGCAGTCCCGGGACAGGATGTTCTCCAAGTTCACCTCCATCC
TGCAGCACGCCGTGGAGGCGCTTGCACCTTCTCTTCCTTTACAAGAAGATTTTGTTTATCACTGGAAGGCAATTACCCATTACTACATAG
AGACTTCAGATGATAAAGCCCCAGTGACCGATACAAATATTCCATCGCATCTGGAACAGATGTTAGATATACTGGTTCAAGAAGAAAATG
AACGGGAATCTGGAGAGACAGGGCCATGTATGGAATATTTGCTTCATCACAAGATCTTGGAAACATTATATACCTTGGGGAAAGCTGATG
AAGCTGCCACTTTTGCTAGAGAGCAAGGCTTTGAGACTAAAGACATTAAAGAGATAGCCAAAAAGACACAAGCCCTGCCAAAGATGAACT
CAAAGAGGCAGCGAATCGTGATCTTCACCCAAGGGAGAGATGACACTATAATGGCTACAGAAAGTGAAGTCACTGCTTTTGCTGTCTTGG
ATCAAGACCAGAAAGAAATTATTGATACCAATGGAGCTGGAGATGCATTTGTTGGAGGTTTTCTGTCTCAACTGGTCTCTGACAAGCCTC
TGACTGAATGTATCCGTGCTGGCCACTATGCAGCAAGCATCATAATTAGACGGACTGGCTGCACCTTTCCTGAGAAGCCAGACTTCCACT
GATGGAAGAGCTGAAAACACAAGCCCAGGAGTGCAGACACTGCCCTAATTGCTTCCTGAGAATTCCCATATTAATAAAGAAGAAAATTAT
CTGCCATTTTTTCCTACTATAATAATGCTGAATCTTAATTTAGAGGGTACAAGGGTATGGTAATGCTTGTAGAATCTTTATTATCTCAAC
AATCTAAAAAATGATGTTTATTTCCATAGTTTGATAGTGCCACTTAAATGCCAATTAAACAAGAATATAACATTTC

>28619_28619_7_FAM160B1-ADK_FAM160B1_chr10_116593161_ENST00000369248_ADK_chr10_76349040_ENST00000539909_length(amino acids)=315AA_BP=195
MPPCPNRCRRRSFSGPRVLAERPPRRPPRPGALRSRRAARAHLKRPGQALPRSSARPPRPAPAFTLERPRQPQQGRRRRIEELSRSSRER
LLQSRDRMFSKFTSILQHAVEALAPSLPLQEDFVYHWKAITHYYIETSDDKAPVTDTNIPSHLEQMLDILVQEENERESGETGPCMEYLL
HHKILETLYTLGKADEAATFAREQGFETKDIKEIAKKTQALPKMNSKRQRIVIFTQGRDDTIMATESEVTAFAVLDQDQKEIIDTNGAGD
AFVGGFLSQLVSDKPLTECIRAGHYAASIIIRRTGCTFPEKPDFH

--------------------------------------------------------------
>28619_28619_8_FAM160B1-ADK_FAM160B1_chr10_116593161_ENST00000369248_ADK_chr10_76349040_ENST00000541550_length(transcript)=1085nt_BP=629nt
GCAGGCCGCGGCGGGCAGAGCGGGGGGAAGGAACCCGAGCCGGGCTGCCACCGTGTCCCAACCGGTGCCGCCGCCGGAGCTTCTCCGGGC
CCCGAGTCCTCGCCGAACGCCCTCCTCGCCGCCCGCCGCGTCCCGGCGCCCTCCGGAGCCGCCGAGCCGCCCGCGCACACCTGAAGCGGC
CGGGCCAGGCCCTGCCTCGATCCTCAGCTCGTCCTCCCCGCCCCGCACCGGCCTTCACTCTGGAGCGGCCCCGGCAGCCGCAGCAGGGGC
GGCGGCGGCGGATCGAGGAGCTCTCCAGGTCGTCCCGGGAGAGGCTGCTGCAGTCCCGGGACAGGATGTTCTCCAAGTTCACCTCCATCC
TGCAGCACGCCGTGGAGGCGCTTGCACCTTCTCTTCCTTTACAAGAAGATTTTGTTTATCACTGGAAGGCAATTACCCATTACTACATAG
AGACTTCAGATGATAAAGCCCCAGTGACCGATACAAATATTCCATCGCATCTGGAACAGATGTTAGATATACTGGTTCAAGAAGAAAATG
AACGGGAATCTGGAGAGACAGGGCCATGTATGGAATATTTGCTTCATCACAAGATCTTGGAAACATTATATACCTTGGGGAAAGCTGATG
AAGCTGCCACTTTTGCTAGAGAGCAAGGCTTTGAGACTAAAGACATTAAAGAGATAGCCAAAAAGACACAAGCCCTGCCAAAGATGAACT
CAAAGAGGCAGCGAATCGTGATCTTCACCCAAGGGAGAGATGACACTATAATGGCTACAGAAAGTGAAGTCACTGCTTTTGCTGTCTTGG
ATCAAGACCAGAAAGAAATTATTGATACCAATGGAGCTGGAGATGCATTTGTTGGAGGTTTTCTGTCTCAACTGGTCTCTGACAAGCCTC
TGACTGAATGTATCCGTGCTGGCCACTATGCAGCAAGCATCATAATTAGACGGACTGGCTGCACCTTTCCTGAGAAGCCAGACTTCCACT
GATGGAAGAGCTGAAAACACAAGCCCAGGAGTGCAGACACTGCCCTAATTGCTTCCTGAGAATTCCCATATTAATAAAGAAGAAAATTAT
CTGCC

>28619_28619_8_FAM160B1-ADK_FAM160B1_chr10_116593161_ENST00000369248_ADK_chr10_76349040_ENST00000541550_length(amino acids)=315AA_BP=195
MPPCPNRCRRRSFSGPRVLAERPPRRPPRPGALRSRRAARAHLKRPGQALPRSSARPPRPAPAFTLERPRQPQQGRRRRIEELSRSSRER
LLQSRDRMFSKFTSILQHAVEALAPSLPLQEDFVYHWKAITHYYIETSDDKAPVTDTNIPSHLEQMLDILVQEENERESGETGPCMEYLL
HHKILETLYTLGKADEAATFAREQGFETKDIKEIAKKTQALPKMNSKRQRIVIFTQGRDDTIMATESEVTAFAVLDQDQKEIIDTNGAGD
AFVGGFLSQLVSDKPLTECIRAGHYAASIIIRRTGCTFPEKPDFH

--------------------------------------------------------------
>28619_28619_9_FAM160B1-ADK_FAM160B1_chr10_116593161_ENST00000369250_ADK_chr10_76349040_ENST00000286621_length(transcript)=1022nt_BP=629nt
GCAGGCCGCGGCGGGCAGAGCGGGGGGAAGGAACCCGAGCCGGGCTGCCACCGTGTCCCAACCGGTGCCGCCGCCGGAGCTTCTCCGGGC
CCCGAGTCCTCGCCGAACGCCCTCCTCGCCGCCCGCCGCGTCCCGGCGCCCTCCGGAGCCGCCGAGCCGCCCGCGCACACCTGAAGCGGC
CGGGCCAGGCCCTGCCTCGATCCTCAGCTCGTCCTCCCCGCCCCGCACCGGCCTTCACTCTGGAGCGGCCCCGGCAGCCGCAGCAGGGGC
GGCGGCGGCGGATCGAGGAGCTCTCCAGGTCGTCCCGGGAGAGGCTGCTGCAGTCCCGGGACAGGATGTTCTCCAAGTTCACCTCCATCC
TGCAGCACGCCGTGGAGGCGCTTGCACCTTCTCTTCCTTTACAAGAAGATTTTGTTTATCACTGGAAGGCAATTACCCATTACTACATAG
AGACTTCAGATGATAAAGCCCCAGTGACCGATACAAATATTCCATCGCATCTGGAACAGATGTTAGATATACTGGTTCAAGAAGAAAATG
AACGGGAATCTGGAGAGACAGGGCCATGTATGGAATATTTGCTTCATCACAAGATCTTGGAAACATTATATACCTTGGGGAAAGCTGATG
AAGCTGCCACTTTTGCTAGAGAGCAAGGCTTTGAGACTAAAGACATTAAAGAGATAGCCAAAAAGACACAAGCCCTGCCAAAGATGAACT
CAAAGAGGCAGCGAATCGTGATCTTCACCCAAGGGAGAGATGACACTATAATGGCTACAGAAAGTGAAGTCACTGCTTTTGCTGTCTTGG
ATCAAGACCAGAAAGAAATTATTGATACCAATGGAGCTGGAGATGCATTTGTTGGAGGTTTTCTGTCTCAACTGGTCTCTGACAAGCCTC
TGACTGAATGTATCCGTGCTGGCCACTATGCAGCAAGCATCATAATTAGACGGACTGGCTGCACCTTTCCTGAGAAGCCAGACTTCCACT
GATGGAAGAGCTGAAAACACAAGCCCAGGAGT

>28619_28619_9_FAM160B1-ADK_FAM160B1_chr10_116593161_ENST00000369250_ADK_chr10_76349040_ENST00000286621_length(amino acids)=315AA_BP=195
MPPCPNRCRRRSFSGPRVLAERPPRRPPRPGALRSRRAARAHLKRPGQALPRSSARPPRPAPAFTLERPRQPQQGRRRRIEELSRSSRER
LLQSRDRMFSKFTSILQHAVEALAPSLPLQEDFVYHWKAITHYYIETSDDKAPVTDTNIPSHLEQMLDILVQEENERESGETGPCMEYLL
HHKILETLYTLGKADEAATFAREQGFETKDIKEIAKKTQALPKMNSKRQRIVIFTQGRDDTIMATESEVTAFAVLDQDQKEIIDTNGAGD
AFVGGFLSQLVSDKPLTECIRAGHYAASIIIRRTGCTFPEKPDFH

--------------------------------------------------------------
>28619_28619_10_FAM160B1-ADK_FAM160B1_chr10_116593161_ENST00000369250_ADK_chr10_76349040_ENST00000372734_length(transcript)=1850nt_BP=629nt
GCAGGCCGCGGCGGGCAGAGCGGGGGGAAGGAACCCGAGCCGGGCTGCCACCGTGTCCCAACCGGTGCCGCCGCCGGAGCTTCTCCGGGC
CCCGAGTCCTCGCCGAACGCCCTCCTCGCCGCCCGCCGCGTCCCGGCGCCCTCCGGAGCCGCCGAGCCGCCCGCGCACACCTGAAGCGGC
CGGGCCAGGCCCTGCCTCGATCCTCAGCTCGTCCTCCCCGCCCCGCACCGGCCTTCACTCTGGAGCGGCCCCGGCAGCCGCAGCAGGGGC
GGCGGCGGCGGATCGAGGAGCTCTCCAGGTCGTCCCGGGAGAGGCTGCTGCAGTCCCGGGACAGGATGTTCTCCAAGTTCACCTCCATCC
TGCAGCACGCCGTGGAGGCGCTTGCACCTTCTCTTCCTTTACAAGAAGATTTTGTTTATCACTGGAAGGCAATTACCCATTACTACATAG
AGACTTCAGATGATAAAGCCCCAGTGACCGATACAAATATTCCATCGCATCTGGAACAGATGTTAGATATACTGGTTCAAGAAGAAAATG
AACGGGAATCTGGAGAGACAGGGCCATGTATGGAATATTTGCTTCATCACAAGATCTTGGAAACATTATATACCTTGGGGAAAGCTGATG
AAGCTGCCACTTTTGCTAGAGAGCAAGGCTTTGAGACTAAAGACATTAAAGAGATAGCCAAAAAGACACAAGCCCTGCCAAAGATGAACT
CAAAGAGGCAGCGAATCGTGATCTTCACCCAAGGGAGAGATGACACTATAATGGCTACAGAAAGTGAAGTCACTGCTTTTGCTGTCTTGG
ATCAAGACCAGAAAGAAATTATTGATACCAATGGAGCTGGAGATGCATTTGTTGGAGGTTTTCTGTCTCAACTGGTCTCTGACAAGCCTC
TGACTGAATGTATCCGTGCTGGCCACTATGCAGCAAGCATCATAATTAGACGGACTGGCTGCACCTTTCCTGAGAAGCCAGACTTCCACT
GATGGAAGAGCTGAAAACACAAGCCCAGGAGTGCAGACACTGCCCTAATTGCTTCCTGAGAATTCCCATATTAATAAAGAAGAAAATTAT
CTGCCATTTTTTCCTACTATAATAATGCTGAATCTTAATTTAGAGGGTACAAGGGTATGGTAATGCTTGTAGAATCTTTATTATCTCAAC
AATCTAAAAAATGATGTTTATTTCCATAGTTTGATAGTGCCACTTAAATGCCAATTAAACAAGAATATAACATTTCAATAGAAATTTTTA
TTTCATTTTCAATTACTTTGTAAATTCGTGTGTATTTAGTACACTGATTTGTTTTTTTACATTTCTGCTTTGAATGCAGATGCAATTTAA
TATAATAGATTTTTTAATGAATTAATCTTAACATAGTAATCTTTAGCTTTTTATACAAATATATTTAATTTAGGAGTATATGTGTGTCTA
TACACACACATACATAAATATACCACATATACACCTGATAGTCAAATAAGGTACAGAAATTTTATCTTGTCAATTATGCCAAATAATCTC
TTTAATGTGCACTCAAACATGTAATAAACTTTGGATAATTAAATAATGTGCCAAATTTAAGTTGTACCACAATATTCAAATCATAGTCTT
ATGGAACTCTGTAATTGGACACAAACAAAAACTTGTCATATAGGAATTTTTTTCTGTCTTTTCCCTGTGTACAGCAAACTGAGGAAGAAA
GATCATTATTTAATACTGGGCCCTGAAATGACACCCAATTTGTTAATGGAATTATGAAGAACAGCAATATAATACACTGAAGAATAACTT
AGTATCAGAGACCAATAAATCACTTTTTTAAGGATGACAAAATGGTATAA

>28619_28619_10_FAM160B1-ADK_FAM160B1_chr10_116593161_ENST00000369250_ADK_chr10_76349040_ENST00000372734_length(amino acids)=315AA_BP=195
MPPCPNRCRRRSFSGPRVLAERPPRRPPRPGALRSRRAARAHLKRPGQALPRSSARPPRPAPAFTLERPRQPQQGRRRRIEELSRSSRER
LLQSRDRMFSKFTSILQHAVEALAPSLPLQEDFVYHWKAITHYYIETSDDKAPVTDTNIPSHLEQMLDILVQEENERESGETGPCMEYLL
HHKILETLYTLGKADEAATFAREQGFETKDIKEIAKKTQALPKMNSKRQRIVIFTQGRDDTIMATESEVTAFAVLDQDQKEIIDTNGAGD
AFVGGFLSQLVSDKPLTECIRAGHYAASIIIRRTGCTFPEKPDFH

--------------------------------------------------------------
>28619_28619_11_FAM160B1-ADK_FAM160B1_chr10_116593161_ENST00000369250_ADK_chr10_76349040_ENST00000539909_length(transcript)=1246nt_BP=629nt
GCAGGCCGCGGCGGGCAGAGCGGGGGGAAGGAACCCGAGCCGGGCTGCCACCGTGTCCCAACCGGTGCCGCCGCCGGAGCTTCTCCGGGC
CCCGAGTCCTCGCCGAACGCCCTCCTCGCCGCCCGCCGCGTCCCGGCGCCCTCCGGAGCCGCCGAGCCGCCCGCGCACACCTGAAGCGGC
CGGGCCAGGCCCTGCCTCGATCCTCAGCTCGTCCTCCCCGCCCCGCACCGGCCTTCACTCTGGAGCGGCCCCGGCAGCCGCAGCAGGGGC
GGCGGCGGCGGATCGAGGAGCTCTCCAGGTCGTCCCGGGAGAGGCTGCTGCAGTCCCGGGACAGGATGTTCTCCAAGTTCACCTCCATCC
TGCAGCACGCCGTGGAGGCGCTTGCACCTTCTCTTCCTTTACAAGAAGATTTTGTTTATCACTGGAAGGCAATTACCCATTACTACATAG
AGACTTCAGATGATAAAGCCCCAGTGACCGATACAAATATTCCATCGCATCTGGAACAGATGTTAGATATACTGGTTCAAGAAGAAAATG
AACGGGAATCTGGAGAGACAGGGCCATGTATGGAATATTTGCTTCATCACAAGATCTTGGAAACATTATATACCTTGGGGAAAGCTGATG
AAGCTGCCACTTTTGCTAGAGAGCAAGGCTTTGAGACTAAAGACATTAAAGAGATAGCCAAAAAGACACAAGCCCTGCCAAAGATGAACT
CAAAGAGGCAGCGAATCGTGATCTTCACCCAAGGGAGAGATGACACTATAATGGCTACAGAAAGTGAAGTCACTGCTTTTGCTGTCTTGG
ATCAAGACCAGAAAGAAATTATTGATACCAATGGAGCTGGAGATGCATTTGTTGGAGGTTTTCTGTCTCAACTGGTCTCTGACAAGCCTC
TGACTGAATGTATCCGTGCTGGCCACTATGCAGCAAGCATCATAATTAGACGGACTGGCTGCACCTTTCCTGAGAAGCCAGACTTCCACT
GATGGAAGAGCTGAAAACACAAGCCCAGGAGTGCAGACACTGCCCTAATTGCTTCCTGAGAATTCCCATATTAATAAAGAAGAAAATTAT
CTGCCATTTTTTCCTACTATAATAATGCTGAATCTTAATTTAGAGGGTACAAGGGTATGGTAATGCTTGTAGAATCTTTATTATCTCAAC
AATCTAAAAAATGATGTTTATTTCCATAGTTTGATAGTGCCACTTAAATGCCAATTAAACAAGAATATAACATTTC

>28619_28619_11_FAM160B1-ADK_FAM160B1_chr10_116593161_ENST00000369250_ADK_chr10_76349040_ENST00000539909_length(amino acids)=315AA_BP=195
MPPCPNRCRRRSFSGPRVLAERPPRRPPRPGALRSRRAARAHLKRPGQALPRSSARPPRPAPAFTLERPRQPQQGRRRRIEELSRSSRER
LLQSRDRMFSKFTSILQHAVEALAPSLPLQEDFVYHWKAITHYYIETSDDKAPVTDTNIPSHLEQMLDILVQEENERESGETGPCMEYLL
HHKILETLYTLGKADEAATFAREQGFETKDIKEIAKKTQALPKMNSKRQRIVIFTQGRDDTIMATESEVTAFAVLDQDQKEIIDTNGAGD
AFVGGFLSQLVSDKPLTECIRAGHYAASIIIRRTGCTFPEKPDFH

--------------------------------------------------------------
>28619_28619_12_FAM160B1-ADK_FAM160B1_chr10_116593161_ENST00000369250_ADK_chr10_76349040_ENST00000541550_length(transcript)=1085nt_BP=629nt
GCAGGCCGCGGCGGGCAGAGCGGGGGGAAGGAACCCGAGCCGGGCTGCCACCGTGTCCCAACCGGTGCCGCCGCCGGAGCTTCTCCGGGC
CCCGAGTCCTCGCCGAACGCCCTCCTCGCCGCCCGCCGCGTCCCGGCGCCCTCCGGAGCCGCCGAGCCGCCCGCGCACACCTGAAGCGGC
CGGGCCAGGCCCTGCCTCGATCCTCAGCTCGTCCTCCCCGCCCCGCACCGGCCTTCACTCTGGAGCGGCCCCGGCAGCCGCAGCAGGGGC
GGCGGCGGCGGATCGAGGAGCTCTCCAGGTCGTCCCGGGAGAGGCTGCTGCAGTCCCGGGACAGGATGTTCTCCAAGTTCACCTCCATCC
TGCAGCACGCCGTGGAGGCGCTTGCACCTTCTCTTCCTTTACAAGAAGATTTTGTTTATCACTGGAAGGCAATTACCCATTACTACATAG
AGACTTCAGATGATAAAGCCCCAGTGACCGATACAAATATTCCATCGCATCTGGAACAGATGTTAGATATACTGGTTCAAGAAGAAAATG
AACGGGAATCTGGAGAGACAGGGCCATGTATGGAATATTTGCTTCATCACAAGATCTTGGAAACATTATATACCTTGGGGAAAGCTGATG
AAGCTGCCACTTTTGCTAGAGAGCAAGGCTTTGAGACTAAAGACATTAAAGAGATAGCCAAAAAGACACAAGCCCTGCCAAAGATGAACT
CAAAGAGGCAGCGAATCGTGATCTTCACCCAAGGGAGAGATGACACTATAATGGCTACAGAAAGTGAAGTCACTGCTTTTGCTGTCTTGG
ATCAAGACCAGAAAGAAATTATTGATACCAATGGAGCTGGAGATGCATTTGTTGGAGGTTTTCTGTCTCAACTGGTCTCTGACAAGCCTC
TGACTGAATGTATCCGTGCTGGCCACTATGCAGCAAGCATCATAATTAGACGGACTGGCTGCACCTTTCCTGAGAAGCCAGACTTCCACT
GATGGAAGAGCTGAAAACACAAGCCCAGGAGTGCAGACACTGCCCTAATTGCTTCCTGAGAATTCCCATATTAATAAAGAAGAAAATTAT
CTGCC

>28619_28619_12_FAM160B1-ADK_FAM160B1_chr10_116593161_ENST00000369250_ADK_chr10_76349040_ENST00000541550_length(amino acids)=315AA_BP=195
MPPCPNRCRRRSFSGPRVLAERPPRRPPRPGALRSRRAARAHLKRPGQALPRSSARPPRPAPAFTLERPRQPQQGRRRRIEELSRSSRER
LLQSRDRMFSKFTSILQHAVEALAPSLPLQEDFVYHWKAITHYYIETSDDKAPVTDTNIPSHLEQMLDILVQEENERESGETGPCMEYLL
HHKILETLYTLGKADEAATFAREQGFETKDIKEIAKKTQALPKMNSKRQRIVIFTQGRDDTIMATESEVTAFAVLDQDQKEIIDTNGAGD
AFVGGFLSQLVSDKPLTECIRAGHYAASIIIRRTGCTFPEKPDFH

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for FAM160B1-ADK


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for FAM160B1-ADK


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
TgeneADKP55263DB00131Adenosine phosphateProduct ofSmall moleculeApproved|Investigational|Nutraceutical

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Related Diseases for FAM160B1-ADK


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneFAM160B1C0025202melanoma1CTD_human
HgeneFAM160B1C0557874Global developmental delay1GENOMICS_ENGLAND
HgeneFAM160B1C1842364Central hypotonia1GENOMICS_ENGLAND
HgeneFAM160B1C3714756Intellectual Disability1GENOMICS_ENGLAND
HgeneFAM160B1C4025871Abnormality of the face1GENOMICS_ENGLAND
TgeneC3280381HYPERMETHIONINEMIA DUE TO ADENOSINE KINASE DEFICIENCY2CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneC0003129Anoxemia1CTD_human
TgeneC0003130Anoxia1CTD_human
TgeneC0020796Profound Mental Retardation1CTD_human
TgeneC0025363Mental Retardation, Psychosocial1CTD_human
TgeneC0036341Schizophrenia1PSYGENET
TgeneC0242184Hypoxia1CTD_human
TgeneC0700292Hypoxemia1CTD_human
TgeneC0917816Mental deficiency1CTD_human
TgeneC3714756Intellectual Disability1CTD_human