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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Diseases

Fusion gene:ABCD3-AK5 (FusionGDB2 ID:HG5825TG26289)

Fusion Gene Summary for ABCD3-AK5

check button Fusion gene summary
Fusion gene informationFusion gene name: ABCD3-AK5
Fusion gene ID: hg5825tg26289
HgeneTgene
Gene symbol

ABCD3

AK5

Gene ID

5825

26289

Gene nameATP binding cassette subfamily D member 3adenylate kinase 5
SynonymsABC43|CBAS5|PMP70|PXMP1|ZWS2AK6
Cytomap('ABCD3')('AK5')

1p21.3

1p31.1

Type of geneprotein-codingprotein-coding
DescriptionATP-binding cassette sub-family D member 370 kDa peroxisomal membrane proteinATP-binding cassette, sub-family D (ALD), member 3Peroxisomal membrane protein-1 (70kD)dJ824O18.1 (ATP-binding cassette, sub-family D (ALD), member 3 (PMP70, PXMP1))peroxisoadenylate kinase isoenzyme 5AK 5ATP-AMP transphosphorylase 5adenylate kinase 6
Modification date2020031320200313
UniProtAcc.

Q9Y6K8

Ensembl transtripts involved in fusion geneENST00000484213, ENST00000370214, 
ENST00000394233, ENST00000454898, 
ENST00000536817, ENST00000315713, 
Fusion gene scores* DoF score6 X 5 X 4=1207 X 6 X 6=252
# samples 67
** MAII scorelog2(6/120*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/252*10)=-1.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ABCD3 [Title/Abstract] AND AK5 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointABCD3(94965170)-AK5(77876666), # samples:1
Anticipated loss of major functional domain due to fusion event.ABCD3-AK5 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ABCD3-AK5 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ABCD3-AK5 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ABCD3-AK5 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneABCD3

GO:0007031

peroxisome organization

9425230

TgeneAK5

GO:0006165

nucleoside diphosphate phosphorylation

23416111

TgeneAK5

GO:0009142

nucleoside triphosphate biosynthetic process

23416111


check buttonFusion gene breakpoints across ABCD3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across AK5 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-66-2756-01AABCD3chr1

94965170

-AK5chr1

77876666

+


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Fusion Gene ORF analysis for ABCD3-AK5

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000484213ENST00000344720ABCD3chr1

94965170

-AK5chr1

77876666

+
3UTR-3CDSENST00000484213ENST00000354567ABCD3chr1

94965170

-AK5chr1

77876666

+
3UTR-intronENST00000484213ENST00000317704ABCD3chr1

94965170

-AK5chr1

77876666

+
3UTR-intronENST00000484213ENST00000478255ABCD3chr1

94965170

-AK5chr1

77876666

+
5CDS-intronENST00000370214ENST00000317704ABCD3chr1

94965170

-AK5chr1

77876666

+
5CDS-intronENST00000370214ENST00000478255ABCD3chr1

94965170

-AK5chr1

77876666

+
5CDS-intronENST00000394233ENST00000317704ABCD3chr1

94965170

-AK5chr1

77876666

+
5CDS-intronENST00000394233ENST00000478255ABCD3chr1

94965170

-AK5chr1

77876666

+
5CDS-intronENST00000454898ENST00000317704ABCD3chr1

94965170

-AK5chr1

77876666

+
5CDS-intronENST00000454898ENST00000478255ABCD3chr1

94965170

-AK5chr1

77876666

+
5CDS-intronENST00000536817ENST00000317704ABCD3chr1

94965170

-AK5chr1

77876666

+
5CDS-intronENST00000536817ENST00000478255ABCD3chr1

94965170

-AK5chr1

77876666

+
In-frameENST00000370214ENST00000344720ABCD3chr1

94965170

-AK5chr1

77876666

+
In-frameENST00000370214ENST00000354567ABCD3chr1

94965170

-AK5chr1

77876666

+
In-frameENST00000394233ENST00000344720ABCD3chr1

94965170

-AK5chr1

77876666

+
In-frameENST00000394233ENST00000354567ABCD3chr1

94965170

-AK5chr1

77876666

+
In-frameENST00000454898ENST00000344720ABCD3chr1

94965170

-AK5chr1

77876666

+
In-frameENST00000454898ENST00000354567ABCD3chr1

94965170

-AK5chr1

77876666

+
In-frameENST00000536817ENST00000344720ABCD3chr1

94965170

-AK5chr1

77876666

+
In-frameENST00000536817ENST00000354567ABCD3chr1

94965170

-AK5chr1

77876666

+
intron-3CDSENST00000315713ENST00000344720ABCD3chr1

94965170

-AK5chr1

77876666

+
intron-3CDSENST00000315713ENST00000354567ABCD3chr1

94965170

-AK5chr1

77876666

+
intron-intronENST00000315713ENST00000317704ABCD3chr1

94965170

-AK5chr1

77876666

+
intron-intronENST00000315713ENST00000478255ABCD3chr1

94965170

-AK5chr1

77876666

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000394233ABCD3chr194965170-ENST00000354567AK5chr177876666+360615121022309735
ENST00000394233ABCD3chr194965170-ENST00000344720AK5chr177876666+360215121022309735
ENST00000454898ABCD3chr194965170-ENST00000354567AK5chr177876666+39721878662675869
ENST00000454898ABCD3chr194965170-ENST00000344720AK5chr177876666+39681878662675869
ENST00000536817ABCD3chr194965170-ENST00000354567AK5chr177876666+386117671322564810
ENST00000536817ABCD3chr194965170-ENST00000344720AK5chr177876666+385717671322564810
ENST00000370214ABCD3chr194965170-ENST00000354567AK5chr177876666+38581764242561845
ENST00000370214ABCD3chr194965170-ENST00000344720AK5chr177876666+38541764242561845

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000394233ENST00000354567ABCD3chr194965170-AK5chr177876666+0.0002243710.9997756
ENST00000394233ENST00000344720ABCD3chr194965170-AK5chr177876666+0.0002241530.9997758
ENST00000454898ENST00000354567ABCD3chr194965170-AK5chr177876666+0.0003500450.99965
ENST00000454898ENST00000344720ABCD3chr194965170-AK5chr177876666+0.0003505770.9996494
ENST00000536817ENST00000354567ABCD3chr194965170-AK5chr177876666+0.0003690760.9996309
ENST00000536817ENST00000344720ABCD3chr194965170-AK5chr177876666+0.0003690220.9996309
ENST00000370214ENST00000354567ABCD3chr194965170-AK5chr177876666+0.0001391150.9998609
ENST00000370214ENST00000344720ABCD3chr194965170-AK5chr177876666+0.0001388650.9998611

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Fusion Genomic Features for ABCD3-AK5


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for ABCD3-AK5


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:94965170/chr1:77876666)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.AK5

Q9Y6K8

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Active on AMP and dAMP with ATP as a donor. When GTP is used as phosphate donor, the enzyme phosphorylates AMP, CMP, and to a small extent dCMP. Also displays broad nucleoside diphosphate kinase activity. {ECO:0000269|PubMed:19647735, ECO:0000269|PubMed:23416111}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneABCD3chr1:94965170chr1:77876666ENST00000370214-202385_372580660.0DomainABC transmembrane type-1
HgeneABCD3chr1:94965170chr1:77876666ENST00000394233-161985_372470550.0DomainABC transmembrane type-1
HgeneABCD3chr1:94965170chr1:77876666ENST00000370214-2023473_480580660.0Nucleotide bindingATP
HgeneABCD3chr1:94965170chr1:77876666ENST00000370214-20231_124580660.0RegionNote=Targeting to peroxisomes
HgeneABCD3chr1:94965170chr1:77876666ENST00000394233-16191_124470550.0RegionNote=Targeting to peroxisomes
HgeneABCD3chr1:94965170chr1:77876666ENST00000370214-2023126_146580660.0TransmembraneHelical
HgeneABCD3chr1:94965170chr1:77876666ENST00000370214-2023224_244580660.0TransmembraneHelical
HgeneABCD3chr1:94965170chr1:77876666ENST00000370214-2023313_333580660.0TransmembraneHelical
HgeneABCD3chr1:94965170chr1:77876666ENST00000370214-202384_104580660.0TransmembraneHelical
HgeneABCD3chr1:94965170chr1:77876666ENST00000394233-1619126_146470550.0TransmembraneHelical
HgeneABCD3chr1:94965170chr1:77876666ENST00000394233-1619224_244470550.0TransmembraneHelical
HgeneABCD3chr1:94965170chr1:77876666ENST00000394233-1619313_333470550.0TransmembraneHelical
HgeneABCD3chr1:94965170chr1:77876666ENST00000394233-161984_104470550.0TransmembraneHelical
TgeneAK5chr1:94965170chr1:77876666ENST00000344720514386_391271537.0Nucleotide bindingATP 2
TgeneAK5chr1:94965170chr1:77876666ENST00000344720514433_435271537.0Nucleotide bindingAMP 2
TgeneAK5chr1:94965170chr1:77876666ENST00000344720514462_465271537.0Nucleotide bindingAMP 2
TgeneAK5chr1:94965170chr1:77876666ENST00000354567514386_391297563.0Nucleotide bindingATP 2
TgeneAK5chr1:94965170chr1:77876666ENST00000354567514433_435297563.0Nucleotide bindingAMP 2
TgeneAK5chr1:94965170chr1:77876666ENST00000354567514462_465297563.0Nucleotide bindingAMP 2
TgeneAK5chr1:94965170chr1:77876666ENST00000344720514377_559271537.0RegionAdenylate kinase 2
TgeneAK5chr1:94965170chr1:77876666ENST00000344720514406_435271537.0RegionNMP 2
TgeneAK5chr1:94965170chr1:77876666ENST00000344720514499_509271537.0RegionLID 2
TgeneAK5chr1:94965170chr1:77876666ENST00000354567514377_559297563.0RegionAdenylate kinase 2
TgeneAK5chr1:94965170chr1:77876666ENST00000354567514406_435297563.0RegionNMP 2
TgeneAK5chr1:94965170chr1:77876666ENST00000354567514499_509297563.0RegionLID 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneABCD3chr1:94965170chr1:77876666ENST00000315713-19440_6590237.0DomainABC transporter
HgeneABCD3chr1:94965170chr1:77876666ENST00000315713-1985_3720237.0DomainABC transmembrane type-1
HgeneABCD3chr1:94965170chr1:77876666ENST00000370214-2023440_659580660.0DomainABC transporter
HgeneABCD3chr1:94965170chr1:77876666ENST00000394233-1619440_659470550.0DomainABC transporter
HgeneABCD3chr1:94965170chr1:77876666ENST00000315713-19473_4800237.0Nucleotide bindingATP
HgeneABCD3chr1:94965170chr1:77876666ENST00000394233-1619473_480470550.0Nucleotide bindingATP
HgeneABCD3chr1:94965170chr1:77876666ENST00000315713-191_1240237.0RegionNote=Targeting to peroxisomes
HgeneABCD3chr1:94965170chr1:77876666ENST00000315713-19126_1460237.0TransmembraneHelical
HgeneABCD3chr1:94965170chr1:77876666ENST00000315713-19224_2440237.0TransmembraneHelical
HgeneABCD3chr1:94965170chr1:77876666ENST00000315713-19313_3330237.0TransmembraneHelical
HgeneABCD3chr1:94965170chr1:77876666ENST00000315713-1984_1040237.0TransmembraneHelical
TgeneAK5chr1:94965170chr1:77876666ENST00000344720514142_147271537.0Nucleotide bindingATP 1
TgeneAK5chr1:94965170chr1:77876666ENST00000344720514191_193271537.0Nucleotide bindingAMP 1
TgeneAK5chr1:94965170chr1:77876666ENST00000344720514219_222271537.0Nucleotide bindingAMP 1
TgeneAK5chr1:94965170chr1:77876666ENST00000354567514142_147297563.0Nucleotide bindingATP 1
TgeneAK5chr1:94965170chr1:77876666ENST00000354567514191_193297563.0Nucleotide bindingAMP 1
TgeneAK5chr1:94965170chr1:77876666ENST00000354567514219_222297563.0Nucleotide bindingAMP 1
TgeneAK5chr1:94965170chr1:77876666ENST00000344720514133_316271537.0RegionAdenylate kinase 1
TgeneAK5chr1:94965170chr1:77876666ENST00000344720514162_193271537.0RegionNMP 1
TgeneAK5chr1:94965170chr1:77876666ENST00000344720514256_266271537.0RegionLID 1
TgeneAK5chr1:94965170chr1:77876666ENST00000354567514133_316297563.0RegionAdenylate kinase 1
TgeneAK5chr1:94965170chr1:77876666ENST00000354567514162_193297563.0RegionNMP 1
TgeneAK5chr1:94965170chr1:77876666ENST00000354567514256_266297563.0RegionLID 1


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Fusion Gene Sequence for ABCD3-AK5


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>323_323_1_ABCD3-AK5_ABCD3_chr1_94965170_ENST00000370214_AK5_chr1_77876666_ENST00000344720_length(transcript)=3854nt_BP=1764nt
CGGCTCGCTGGTACCGGCAGTGCCATGGCGGCCTTCAGCAAGTACTTGACGGCGCGAAACTCCTCGCTGGCTGGTGCCGCGTTCCTGCTG
CTCTGCCTGCTCCACAAGCGGCGCCGCGCCCTCGGCCTGCACGGTAAGAAAAGTGGAAAACCACCATTACAGAACAATGAGAAAGAGGGG
AAAAAGGAGCGAGCTGTGGTGGACAAGGTGTTTTTCTCAAGGCTCATACAGATTCTGAAAATCATGGTCCCTAGAACATTTTGTAAAGAG
ACAGGTTACTTGGTACTTATTGCTGTTATGCTGGTGTCTCGAACATATTGTGATGTTTGGATGATTCAAAATGGGACACTAATTGAAAGT
GGTATCATTGGTCGTAGCAGGAAAGATTTCAAGAGATACTTACTCAACTTCATCGCTGCCATGCCTCTTATCTCTCTGGTTAATAACTTC
TTGAAGTATGGGTTAAATGAGCTTAAACTGTGCTTCCGAGTAAGGCTCACTAAATACCTCTATGAGGAGTATCTTCAAGCTTTCACATAT
TATAAAATGGGGAATCTGGACAACAGAATAGCTAATCCAGACCAGCTGCTTACACAAGATGTAGAAAAATTTTGTAACAGTGTAGTCGAT
CTGTATTCAAATCTTAGTAAGCCATTTTTAGACATAGTTTTGTATATCTTTAAGTTAACGAGTGCAATTGGAGCTCAGGGCCCAGCGAGC
ATGATGGCCTACTTGGTTGTTTCTGGGCTATTCCTAACTCGACTTCGAAGACCCATTGGTAAGATGACAATAACTGAGCAAAAGTATGAA
GGAGAATATAGATATGTTAATTCTCGGCTCATCACAAACAGTGAAGAAATTGCCTTTTACAATGGGAATAAAAGAGAAAAGCAGACAGTC
CACTCAGTCTTCCGAAAACTGGTGGAACACCTACATAATTTCATTTTGTTTCGGTTTTCAATGGGCTTCATTGATAGTATTATTGCCAAA
TACCTTGCCACTGTTGTTGGTTACCTAGTTGTCAGTCGCCCTTTCTTAGATTTGTCTCATCCTCGACATCTCAAGAGTACACATTCGGAA
CTTCTAGAGGATTACTACCAAAGTGGAAGAATGCTTTTGCGAATGTCTCAAGCTCTGGGTCGAATAGTTTTGGCTGGGCGTGAAATGACT
AGATTGGCCGGTTTTACTGCTCGGATTACAGAATTAATGCAAGTACTGAAGGATTTAAATCATGGCAAATATGAGCGCACAATGGTCTCA
CAACAGGAAAAGGGTATTGAAGGAGTACAAGTCATTCCCTTGATACCTGGTGCTGGAGAAATCATTATTGCAGATAACATTATAAAGTTT
GATCATGTTCCTTTAGCAACGCCAAATGGAGATGTTTTGATCCGAGACCTTAATTTTGAAGTTCGATCTGGGGCTAATGTTCTAATTTGT
GGTCCAAATGGCTGCGGAAAGAGTTCACTTTTCCGTGTTCTTGGTGAATTATGGCCTCTTTTTGGAGGACGTCTAACTAAACCTGAAAGA
GGAAAATTATTTTATGTTCCTCAGAGACCTTACATGACCCTTGGAACACTTCGAGATCAAGTGATATATCCAGATGGACGAGAAGATCAG
AAAAGGAAGGGAATTTCTGACCTAGTACTGAAGGAATACTTAGACAATGTCCAGTTGGGTCATATCCTTGAACGTGAAGGAGGCTGGGAC
AGTGTTCAGGATTGGATGGACGTACTCAGTGGTGGAGAAAAGCAAAGAATGGCGTTTGATGCCGACCGCGATGAGGATGAGGTGTTCTAT
GACATCAGCATGGCAGTTGACAACAAGTTATTTCCAAACAAAGAGGCTGCAGCAGGTTCAAGTGACCTTGATCCTTCGATGATATTGGAC
ACTGGAGAGATCATTGATACAGGATCTGATTATGAAGATCAGGGTGATGACCAGTTAAATGTATTTGGAGAGGACACTATGGGAGGTTTC
ATGGAAGATTTGAGAAAGTGTAAAATTATTTTCATAATTGGTGGTCCTGGCTCTGGCAAAGGCACACAGTGTGAAAAGCTGGTGGAAAAA
TATGGATTTACACATCTCTCAACTGGCGAGCTCCTGCGTGAGGAACTGGCATCAGAATCTGAAAGAAGCAAATTGATCAGAGACATTATG
GAACGTGGAGACCTGGTGCCCTCAGGCATCGTTTTGGAGCTCCTGAAGGAGGCCATGGTGGCCAGCCTCGGGGACACCAGGGGCTTCCTG
ATTGACGGCTATCCTCGGGAGGTGAAGCAAGGGGAAGAGTTCGGACGCAGGATTGGAGACCCACAGTTGGTGATCTGTATGGACTGCTCG
GCAGACACCATGACCAACCGCCTTCTCCAAAGGAGCCGGAGCAGCCTGCCTGTGGACGACACCACCAAGACCATCGCCAAGCGCCTAGAA
GCCTACTACCGAGCGTCCATCCCCGTGATCGCCTACTACGAGACAAAAACACAGCTACACAAGATAAATGCAGAGGGAACACCAGAGGAC
GTTTTTCTTCAACTCTGCACAGCTATTGACTCTATTTTCTGAAGGCAAAAATGCATGTTTGTTAGAATGGAAACAGAAAAACATTAAAAA
GTTCATTCCTTAACACAATGTTTCAAGTTAAACCTTTTGTGTCACCGCCCCCACCAACCACCACCTCCTAAATCCTGACAGCACTGTTTG
CTTCCCAGCTAGACCTGTGTGAGAGGTGTCTGGAAATCATGCATGGTGTATTTGGGACTATATCAACCTATTCTCCACACTTCAGACAAC
TGTCTGCACTCACGGCACACACACTTTGTATCATGCAGGCCACACTCAGAGCTAGTCAGTACATGAACAGTGGTGCGGTGCCAGTCTGTG
TCCGTTGTGATCACAGGCCTTGCTAGACCCTGATCATCTGGTTCTCCTCTCATTAAGCATCCCTAACCCCCAGTCACACCTTCCTCTTAC
ATACTGTTCCCCAATGGAGGCCCCTGGCATAGGGGACAGCCCTGGGCATCTTCCTTTGGTGTCTGGCTGTTTTGTCAACTCTCATCCACT
GGTGGCTCAGAGCCATAAGGTGGGTTGATTACACAATGCCTTGTACATGATATAGAGGCATCAAGCAAGTAAAATTTGACAGAAATTTTA
AAATATGAAGATGTATAGCTTTCCCAAGATGATGGTAAAACCCAGGTTAGTCATCAGTAACCTTCTCTATTATTATTATTTTTTAGAAAC
TTGGAATACTGTCGTCATGGCTAAGAGAACAAATCTGATAAATTGTGTAACCTAGTCTCTTCTCTACATGGTGATGCATTTCAGCAATTA
TAAATTAATATAAATGACCAAAAGTAACTTAAAAGCATGAGATATTTGCTATTTCATTCATTGGGCACATATCAAATTATAATTTTGATT
TTAAATGGTCACCCATGTATTTATTTGTTGCCAAGCAAGTAAAAAAATACCCTAACAAACCTGATGTGGGTGGGAGGGGCATGTCAGTAA
GTGGTGTGTTCAATGTGTTTGTTTCATATGGGCCCTTTCCAGGAGTTTGCAAACCTTGTCATACCCATATGCAAAACTGTGTTTCCTTGC
ATTAAACCAGTGAAGTTTGGGTTCTCTTTTGTGCTATCAATCAGTTGTAAAATCAGAGCTGCTTATATATTCTACTGGAATAACTGCATC
TTCCACTCAGTCACTACAAAAAAGCATAGTTTCAGTTTGCATGAATTTTTTTTTTTTTCTTCAATGGCTGTGCAGATAAGGATCCATTTC

>323_323_1_ABCD3-AK5_ABCD3_chr1_94965170_ENST00000370214_AK5_chr1_77876666_ENST00000344720_length(amino acids)=845AA_BP=580
MAAFSKYLTARNSSLAGAAFLLLCLLHKRRRALGLHGKKSGKPPLQNNEKEGKKERAVVDKVFFSRLIQILKIMVPRTFCKETGYLVLIA
VMLVSRTYCDVWMIQNGTLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLYEEYLQAFTYYKMGNLDN
RIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTSAIGAQGPASMMAYLVVSGLFLTRLRRPIGKMTITEQKYEGEYRYVNS
RLITNSEEIAFYNGNKREKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSRPFLDLSHPRHLKSTHSELLEDYYQS
GRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLNHGKYERTMVSQQEKGIEGVQVIPLIPGAGEIIIADNIIKFDHVPLATP
NGDVLIRDLNFEVRSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTLGTLRDQVIYPDGREDQKRKGISDL
VLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEKQRMAFDADRDEDEVFYDISMAVDNKLFPNKEAAAGSSDLDPSMILDTGEIIDTG
SDYEDQGDDQLNVFGEDTMGGFMEDLRKCKIIFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIMERGDLVPS
GIVLELLKEAMVASLGDTRGFLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNRLLQRSRSSLPVDDTTKTIAKRLEAYYRASIP

--------------------------------------------------------------
>323_323_2_ABCD3-AK5_ABCD3_chr1_94965170_ENST00000370214_AK5_chr1_77876666_ENST00000354567_length(transcript)=3858nt_BP=1764nt
CGGCTCGCTGGTACCGGCAGTGCCATGGCGGCCTTCAGCAAGTACTTGACGGCGCGAAACTCCTCGCTGGCTGGTGCCGCGTTCCTGCTG
CTCTGCCTGCTCCACAAGCGGCGCCGCGCCCTCGGCCTGCACGGTAAGAAAAGTGGAAAACCACCATTACAGAACAATGAGAAAGAGGGG
AAAAAGGAGCGAGCTGTGGTGGACAAGGTGTTTTTCTCAAGGCTCATACAGATTCTGAAAATCATGGTCCCTAGAACATTTTGTAAAGAG
ACAGGTTACTTGGTACTTATTGCTGTTATGCTGGTGTCTCGAACATATTGTGATGTTTGGATGATTCAAAATGGGACACTAATTGAAAGT
GGTATCATTGGTCGTAGCAGGAAAGATTTCAAGAGATACTTACTCAACTTCATCGCTGCCATGCCTCTTATCTCTCTGGTTAATAACTTC
TTGAAGTATGGGTTAAATGAGCTTAAACTGTGCTTCCGAGTAAGGCTCACTAAATACCTCTATGAGGAGTATCTTCAAGCTTTCACATAT
TATAAAATGGGGAATCTGGACAACAGAATAGCTAATCCAGACCAGCTGCTTACACAAGATGTAGAAAAATTTTGTAACAGTGTAGTCGAT
CTGTATTCAAATCTTAGTAAGCCATTTTTAGACATAGTTTTGTATATCTTTAAGTTAACGAGTGCAATTGGAGCTCAGGGCCCAGCGAGC
ATGATGGCCTACTTGGTTGTTTCTGGGCTATTCCTAACTCGACTTCGAAGACCCATTGGTAAGATGACAATAACTGAGCAAAAGTATGAA
GGAGAATATAGATATGTTAATTCTCGGCTCATCACAAACAGTGAAGAAATTGCCTTTTACAATGGGAATAAAAGAGAAAAGCAGACAGTC
CACTCAGTCTTCCGAAAACTGGTGGAACACCTACATAATTTCATTTTGTTTCGGTTTTCAATGGGCTTCATTGATAGTATTATTGCCAAA
TACCTTGCCACTGTTGTTGGTTACCTAGTTGTCAGTCGCCCTTTCTTAGATTTGTCTCATCCTCGACATCTCAAGAGTACACATTCGGAA
CTTCTAGAGGATTACTACCAAAGTGGAAGAATGCTTTTGCGAATGTCTCAAGCTCTGGGTCGAATAGTTTTGGCTGGGCGTGAAATGACT
AGATTGGCCGGTTTTACTGCTCGGATTACAGAATTAATGCAAGTACTGAAGGATTTAAATCATGGCAAATATGAGCGCACAATGGTCTCA
CAACAGGAAAAGGGTATTGAAGGAGTACAAGTCATTCCCTTGATACCTGGTGCTGGAGAAATCATTATTGCAGATAACATTATAAAGTTT
GATCATGTTCCTTTAGCAACGCCAAATGGAGATGTTTTGATCCGAGACCTTAATTTTGAAGTTCGATCTGGGGCTAATGTTCTAATTTGT
GGTCCAAATGGCTGCGGAAAGAGTTCACTTTTCCGTGTTCTTGGTGAATTATGGCCTCTTTTTGGAGGACGTCTAACTAAACCTGAAAGA
GGAAAATTATTTTATGTTCCTCAGAGACCTTACATGACCCTTGGAACACTTCGAGATCAAGTGATATATCCAGATGGACGAGAAGATCAG
AAAAGGAAGGGAATTTCTGACCTAGTACTGAAGGAATACTTAGACAATGTCCAGTTGGGTCATATCCTTGAACGTGAAGGAGGCTGGGAC
AGTGTTCAGGATTGGATGGACGTACTCAGTGGTGGAGAAAAGCAAAGAATGGCGTTTGATGCCGACCGCGATGAGGATGAGGTGTTCTAT
GACATCAGCATGGCAGTTGACAACAAGTTATTTCCAAACAAAGAGGCTGCAGCAGGTTCAAGTGACCTTGATCCTTCGATGATATTGGAC
ACTGGAGAGATCATTGATACAGGATCTGATTATGAAGATCAGGGTGATGACCAGTTAAATGTATTTGGAGAGGACACTATGGGAGGTTTC
ATGGAAGATTTGAGAAAGTGTAAAATTATTTTCATAATTGGTGGTCCTGGCTCTGGCAAAGGCACACAGTGTGAAAAGCTGGTGGAAAAA
TATGGATTTACACATCTCTCAACTGGCGAGCTCCTGCGTGAGGAACTGGCATCAGAATCTGAAAGAAGCAAATTGATCAGAGACATTATG
GAACGTGGAGACCTGGTGCCCTCAGGCATCGTTTTGGAGCTCCTGAAGGAGGCCATGGTGGCCAGCCTCGGGGACACCAGGGGCTTCCTG
ATTGACGGCTATCCTCGGGAGGTGAAGCAAGGGGAAGAGTTCGGACGCAGGATTGGAGACCCACAGTTGGTGATCTGTATGGACTGCTCG
GCAGACACCATGACCAACCGCCTTCTCCAAAGGAGCCGGAGCAGCCTGCCTGTGGACGACACCACCAAGACCATCGCCAAGCGCCTAGAA
GCCTACTACCGAGCGTCCATCCCCGTGATCGCCTACTACGAGACAAAAACACAGCTACACAAGATAAATGCAGAGGGAACACCAGAGGAC
GTTTTTCTTCAACTCTGCACAGCTATTGACTCTATTTTCTGAAGGCAAAAATGCATGTTTGTTAGAATGGAAACAGAAAAACATTAAAAA
GTTCATTCCTTAACACAATGTTTCAAGTTAAACCTTTTGTGTCACCGCCCCCACCAACCACCACCTCCTAAATCCTGACAGCACTGTTTG
CTTCCCAGCTAGACCTGTGTGAGAGGTGTCTGGAAATCATGCATGGTGTATTTGGGACTATATCAACCTATTCTCCACACTTCAGACAAC
TGTCTGCACTCACGGCACACACACTTTGTATCATGCAGGCCACACTCAGAGCTAGTCAGTACATGAACAGTGGTGCGGTGCCAGTCTGTG
TCCGTTGTGATCACAGGCCTTGCTAGACCCTGATCATCTGGTTCTCCTCTCATTAAGCATCCCTAACCCCCAGTCACACCTTCCTCTTAC
ATACTGTTCCCCAATGGAGGCCCCTGGCATAGGGGACAGCCCTGGGCATCTTCCTTTGGTGTCTGGCTGTTTTGTCAACTCTCATCCACT
GGTGGCTCAGAGCCATAAGGTGGGTTGATTACACAATGCCTTGTACATGATATAGAGGCATCAAGCAAGTAAAATTTGACAGAAATTTTA
AAATATGAAGATGTATAGCTTTCCCAAGATGATGGTAAAACCCAGGTTAGTCATCAGTAACCTTCTCTATTATTATTATTTTTTAGAAAC
TTGGAATACTGTCGTCATGGCTAAGAGAACAAATCTGATAAATTGTGTAACCTAGTCTCTTCTCTACATGGTGATGCATTTCAGCAATTA
TAAATTAATATAAATGACCAAAAGTAACTTAAAAGCATGAGATATTTGCTATTTCATTCATTGGGCACATATCAAATTATAATTTTGATT
TTAAATGGTCACCCATGTATTTATTTGTTGCCAAGCAAGTAAAAAAATACCCTAACAAACCTGATGTGGGTGGGAGGGGCATGTCAGTAA
GTGGTGTGTTCAATGTGTTTGTTTCATATGGGCCCTTTCCAGGAGTTTGCAAACCTTGTCATACCCATATGCAAAACTGTGTTTCCTTGC
ATTAAACCAGTGAAGTTTGGGTTCTCTTTTGTGCTATCAATCAGTTGTAAAATCAGAGCTGCTTATATATTCTACTGGAATAACTGCATC
TTCCACTCAGTCACTACAAAAAAGCATAGTTTCAGTTTGCATGAATTTTTTTTTTTTTCTTCAATGGCTGTGCAGATAAGGATCCATTTC

>323_323_2_ABCD3-AK5_ABCD3_chr1_94965170_ENST00000370214_AK5_chr1_77876666_ENST00000354567_length(amino acids)=845AA_BP=580
MAAFSKYLTARNSSLAGAAFLLLCLLHKRRRALGLHGKKSGKPPLQNNEKEGKKERAVVDKVFFSRLIQILKIMVPRTFCKETGYLVLIA
VMLVSRTYCDVWMIQNGTLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLYEEYLQAFTYYKMGNLDN
RIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTSAIGAQGPASMMAYLVVSGLFLTRLRRPIGKMTITEQKYEGEYRYVNS
RLITNSEEIAFYNGNKREKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSRPFLDLSHPRHLKSTHSELLEDYYQS
GRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLNHGKYERTMVSQQEKGIEGVQVIPLIPGAGEIIIADNIIKFDHVPLATP
NGDVLIRDLNFEVRSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTLGTLRDQVIYPDGREDQKRKGISDL
VLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEKQRMAFDADRDEDEVFYDISMAVDNKLFPNKEAAAGSSDLDPSMILDTGEIIDTG
SDYEDQGDDQLNVFGEDTMGGFMEDLRKCKIIFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIMERGDLVPS
GIVLELLKEAMVASLGDTRGFLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNRLLQRSRSSLPVDDTTKTIAKRLEAYYRASIP

--------------------------------------------------------------
>323_323_3_ABCD3-AK5_ABCD3_chr1_94965170_ENST00000394233_AK5_chr1_77876666_ENST00000344720_length(transcript)=3602nt_BP=1512nt
CTCTGCTCTCCTCCCAGTCTCCCCCGCGCTGCGTGCAGTAAGGTAGCCGCCGCCGCCGCCGCCGCCGCGTCCCCTCGCCGGCTCGCTGGT
ACCGGCAGTGCCATGGCGGCCTTCAGCAAGTACTTGACGGCGCGAAACTCCTCGCTGGCTGGTGCCGCGTTCCTGCTGCTCTGCCTGCTC
CACAAGCGGCGCCGCGCCCTCGGCCTGCACGGTAAGAAAAGTGGAAAACCACCATTACAGAACAATGAGAAAGAGGGGAAAAAGGAGCGA
GCTGTGGTGGACAAGGTGTTTTTCTCAAGGCTCATACAGATTCTGAAAATCATGGTCCCTAGAACATTTTGTAAAGAGACAGGTTACTTG
GTACTTATTGCTGTTATGCTGGTGTCTCGAACATATTGTGATGTTTGGATGATTCAAAATGGGACACTAATTGAAAGTGGTATCATTGGT
CGTAGCAGGAAAGATTTCAAGAGATACTTACTCAACTTCATCGCTGCCATGCCTCTTATCTCTCTGGTTAATAACTTCTTGAAGTATGGG
TTAAATGAGCTTAAACTGTGCTTCCGAGTAAGGCTCACTAAATACCTCTATGAGGAGTATCTTCAAGCTTTCACATATTATAAAATGGGG
AATCTGGACAACAGAATAGCTAATCCAGACCAGCTGCTTACACAAGATGTAGAAAAATTTTGTAACAGTGTAGTCGATCTGTATTCAAAT
CTTAGTAAGCCATTTTTAGACATAGTTTTGTATATCTTTAAGTTAACGAGTGCAATTGGAGCTCAGGGCCCAGCGAGCATGATGGCCTAC
TTGGTTGTTTCTGGGCTATTCCTAACTCGACTTCGAAGACCCATTGGTAAGATGACAATAACTGAGCAAAAGTATGAAGGAGAATATAGA
TATGTTAATTCTCGGCTCATCACAAACAGTTTTACTGCTCGGATTACAGAATTAATGCAAGTACTGAAGGATTTAAATCATGGCAAATAT
GAGCGCACAATGGTCTCACAACAGGAAAAGGGTATTGAAGGAGTACAAGTCATTCCCTTGATACCTGGTGCTGGAGAAATCATTATTGCA
GATAACATTATAAAGTTTGATCATGTTCCTTTAGCAACGCCAAATGGAGATGTTTTGATCCGAGACCTTAATTTTGAAGTTCGATCTGGG
GCTAATGTTCTAATTTGTGGTCCAAATGGCTGCGGAAAGAGTTCACTTTTCCGTGTTCTTGGTGAATTATGGCCTCTTTTTGGAGGACGT
CTAACTAAACCTGAAAGAGGAAAATTATTTTATGTTCCTCAGAGACCTTACATGACCCTTGGAACACTTCGAGATCAAGTGATATATCCA
GATGGACGAGAAGATCAGAAAAGGAAGGGAATTTCTGACCTAGTACTGAAGGAATACTTAGACAATGTCCAGTTGGGTCATATCCTTGAA
CGTGAAGGAGGCTGGGACAGTGTTCAGGATTGGATGGACGTACTCAGTGGTGGAGAAAAGCAAAGAATGGCGTTTGATGCCGACCGCGAT
GAGGATGAGGTGTTCTATGACATCAGCATGGCAGTTGACAACAAGTTATTTCCAAACAAAGAGGCTGCAGCAGGTTCAAGTGACCTTGAT
CCTTCGATGATATTGGACACTGGAGAGATCATTGATACAGGATCTGATTATGAAGATCAGGGTGATGACCAGTTAAATGTATTTGGAGAG
GACACTATGGGAGGTTTCATGGAAGATTTGAGAAAGTGTAAAATTATTTTCATAATTGGTGGTCCTGGCTCTGGCAAAGGCACACAGTGT
GAAAAGCTGGTGGAAAAATATGGATTTACACATCTCTCAACTGGCGAGCTCCTGCGTGAGGAACTGGCATCAGAATCTGAAAGAAGCAAA
TTGATCAGAGACATTATGGAACGTGGAGACCTGGTGCCCTCAGGCATCGTTTTGGAGCTCCTGAAGGAGGCCATGGTGGCCAGCCTCGGG
GACACCAGGGGCTTCCTGATTGACGGCTATCCTCGGGAGGTGAAGCAAGGGGAAGAGTTCGGACGCAGGATTGGAGACCCACAGTTGGTG
ATCTGTATGGACTGCTCGGCAGACACCATGACCAACCGCCTTCTCCAAAGGAGCCGGAGCAGCCTGCCTGTGGACGACACCACCAAGACC
ATCGCCAAGCGCCTAGAAGCCTACTACCGAGCGTCCATCCCCGTGATCGCCTACTACGAGACAAAAACACAGCTACACAAGATAAATGCA
GAGGGAACACCAGAGGACGTTTTTCTTCAACTCTGCACAGCTATTGACTCTATTTTCTGAAGGCAAAAATGCATGTTTGTTAGAATGGAA
ACAGAAAAACATTAAAAAGTTCATTCCTTAACACAATGTTTCAAGTTAAACCTTTTGTGTCACCGCCCCCACCAACCACCACCTCCTAAA
TCCTGACAGCACTGTTTGCTTCCCAGCTAGACCTGTGTGAGAGGTGTCTGGAAATCATGCATGGTGTATTTGGGACTATATCAACCTATT
CTCCACACTTCAGACAACTGTCTGCACTCACGGCACACACACTTTGTATCATGCAGGCCACACTCAGAGCTAGTCAGTACATGAACAGTG
GTGCGGTGCCAGTCTGTGTCCGTTGTGATCACAGGCCTTGCTAGACCCTGATCATCTGGTTCTCCTCTCATTAAGCATCCCTAACCCCCA
GTCACACCTTCCTCTTACATACTGTTCCCCAATGGAGGCCCCTGGCATAGGGGACAGCCCTGGGCATCTTCCTTTGGTGTCTGGCTGTTT
TGTCAACTCTCATCCACTGGTGGCTCAGAGCCATAAGGTGGGTTGATTACACAATGCCTTGTACATGATATAGAGGCATCAAGCAAGTAA
AATTTGACAGAAATTTTAAAATATGAAGATGTATAGCTTTCCCAAGATGATGGTAAAACCCAGGTTAGTCATCAGTAACCTTCTCTATTA
TTATTATTTTTTAGAAACTTGGAATACTGTCGTCATGGCTAAGAGAACAAATCTGATAAATTGTGTAACCTAGTCTCTTCTCTACATGGT
GATGCATTTCAGCAATTATAAATTAATATAAATGACCAAAAGTAACTTAAAAGCATGAGATATTTGCTATTTCATTCATTGGGCACATAT
CAAATTATAATTTTGATTTTAAATGGTCACCCATGTATTTATTTGTTGCCAAGCAAGTAAAAAAATACCCTAACAAACCTGATGTGGGTG
GGAGGGGCATGTCAGTAAGTGGTGTGTTCAATGTGTTTGTTTCATATGGGCCCTTTCCAGGAGTTTGCAAACCTTGTCATACCCATATGC
AAAACTGTGTTTCCTTGCATTAAACCAGTGAAGTTTGGGTTCTCTTTTGTGCTATCAATCAGTTGTAAAATCAGAGCTGCTTATATATTC
TACTGGAATAACTGCATCTTCCACTCAGTCACTACAAAAAAGCATAGTTTCAGTTTGCATGAATTTTTTTTTTTTTCTTCAATGGCTGTG
CAGATAAGGATCCATTTCTGGGATAGAATTGTATTTTTTAAGTCATTTTTTTTTCTTGAAATGGATATGTACAAATAAAATAAATGGAAG

>323_323_3_ABCD3-AK5_ABCD3_chr1_94965170_ENST00000394233_AK5_chr1_77876666_ENST00000344720_length(amino acids)=735AA_BP=470
MAAFSKYLTARNSSLAGAAFLLLCLLHKRRRALGLHGKKSGKPPLQNNEKEGKKERAVVDKVFFSRLIQILKIMVPRTFCKETGYLVLIA
VMLVSRTYCDVWMIQNGTLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLYEEYLQAFTYYKMGNLDN
RIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTSAIGAQGPASMMAYLVVSGLFLTRLRRPIGKMTITEQKYEGEYRYVNS
RLITNSFTARITELMQVLKDLNHGKYERTMVSQQEKGIEGVQVIPLIPGAGEIIIADNIIKFDHVPLATPNGDVLIRDLNFEVRSGANVL
ICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTLGTLRDQVIYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREGG
WDSVQDWMDVLSGGEKQRMAFDADRDEDEVFYDISMAVDNKLFPNKEAAAGSSDLDPSMILDTGEIIDTGSDYEDQGDDQLNVFGEDTMG
GFMEDLRKCKIIFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIMERGDLVPSGIVLELLKEAMVASLGDTRG
FLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNRLLQRSRSSLPVDDTTKTIAKRLEAYYRASIPVIAYYETKTQLHKINAEGTP

--------------------------------------------------------------
>323_323_4_ABCD3-AK5_ABCD3_chr1_94965170_ENST00000394233_AK5_chr1_77876666_ENST00000354567_length(transcript)=3606nt_BP=1512nt
CTCTGCTCTCCTCCCAGTCTCCCCCGCGCTGCGTGCAGTAAGGTAGCCGCCGCCGCCGCCGCCGCCGCGTCCCCTCGCCGGCTCGCTGGT
ACCGGCAGTGCCATGGCGGCCTTCAGCAAGTACTTGACGGCGCGAAACTCCTCGCTGGCTGGTGCCGCGTTCCTGCTGCTCTGCCTGCTC
CACAAGCGGCGCCGCGCCCTCGGCCTGCACGGTAAGAAAAGTGGAAAACCACCATTACAGAACAATGAGAAAGAGGGGAAAAAGGAGCGA
GCTGTGGTGGACAAGGTGTTTTTCTCAAGGCTCATACAGATTCTGAAAATCATGGTCCCTAGAACATTTTGTAAAGAGACAGGTTACTTG
GTACTTATTGCTGTTATGCTGGTGTCTCGAACATATTGTGATGTTTGGATGATTCAAAATGGGACACTAATTGAAAGTGGTATCATTGGT
CGTAGCAGGAAAGATTTCAAGAGATACTTACTCAACTTCATCGCTGCCATGCCTCTTATCTCTCTGGTTAATAACTTCTTGAAGTATGGG
TTAAATGAGCTTAAACTGTGCTTCCGAGTAAGGCTCACTAAATACCTCTATGAGGAGTATCTTCAAGCTTTCACATATTATAAAATGGGG
AATCTGGACAACAGAATAGCTAATCCAGACCAGCTGCTTACACAAGATGTAGAAAAATTTTGTAACAGTGTAGTCGATCTGTATTCAAAT
CTTAGTAAGCCATTTTTAGACATAGTTTTGTATATCTTTAAGTTAACGAGTGCAATTGGAGCTCAGGGCCCAGCGAGCATGATGGCCTAC
TTGGTTGTTTCTGGGCTATTCCTAACTCGACTTCGAAGACCCATTGGTAAGATGACAATAACTGAGCAAAAGTATGAAGGAGAATATAGA
TATGTTAATTCTCGGCTCATCACAAACAGTTTTACTGCTCGGATTACAGAATTAATGCAAGTACTGAAGGATTTAAATCATGGCAAATAT
GAGCGCACAATGGTCTCACAACAGGAAAAGGGTATTGAAGGAGTACAAGTCATTCCCTTGATACCTGGTGCTGGAGAAATCATTATTGCA
GATAACATTATAAAGTTTGATCATGTTCCTTTAGCAACGCCAAATGGAGATGTTTTGATCCGAGACCTTAATTTTGAAGTTCGATCTGGG
GCTAATGTTCTAATTTGTGGTCCAAATGGCTGCGGAAAGAGTTCACTTTTCCGTGTTCTTGGTGAATTATGGCCTCTTTTTGGAGGACGT
CTAACTAAACCTGAAAGAGGAAAATTATTTTATGTTCCTCAGAGACCTTACATGACCCTTGGAACACTTCGAGATCAAGTGATATATCCA
GATGGACGAGAAGATCAGAAAAGGAAGGGAATTTCTGACCTAGTACTGAAGGAATACTTAGACAATGTCCAGTTGGGTCATATCCTTGAA
CGTGAAGGAGGCTGGGACAGTGTTCAGGATTGGATGGACGTACTCAGTGGTGGAGAAAAGCAAAGAATGGCGTTTGATGCCGACCGCGAT
GAGGATGAGGTGTTCTATGACATCAGCATGGCAGTTGACAACAAGTTATTTCCAAACAAAGAGGCTGCAGCAGGTTCAAGTGACCTTGAT
CCTTCGATGATATTGGACACTGGAGAGATCATTGATACAGGATCTGATTATGAAGATCAGGGTGATGACCAGTTAAATGTATTTGGAGAG
GACACTATGGGAGGTTTCATGGAAGATTTGAGAAAGTGTAAAATTATTTTCATAATTGGTGGTCCTGGCTCTGGCAAAGGCACACAGTGT
GAAAAGCTGGTGGAAAAATATGGATTTACACATCTCTCAACTGGCGAGCTCCTGCGTGAGGAACTGGCATCAGAATCTGAAAGAAGCAAA
TTGATCAGAGACATTATGGAACGTGGAGACCTGGTGCCCTCAGGCATCGTTTTGGAGCTCCTGAAGGAGGCCATGGTGGCCAGCCTCGGG
GACACCAGGGGCTTCCTGATTGACGGCTATCCTCGGGAGGTGAAGCAAGGGGAAGAGTTCGGACGCAGGATTGGAGACCCACAGTTGGTG
ATCTGTATGGACTGCTCGGCAGACACCATGACCAACCGCCTTCTCCAAAGGAGCCGGAGCAGCCTGCCTGTGGACGACACCACCAAGACC
ATCGCCAAGCGCCTAGAAGCCTACTACCGAGCGTCCATCCCCGTGATCGCCTACTACGAGACAAAAACACAGCTACACAAGATAAATGCA
GAGGGAACACCAGAGGACGTTTTTCTTCAACTCTGCACAGCTATTGACTCTATTTTCTGAAGGCAAAAATGCATGTTTGTTAGAATGGAA
ACAGAAAAACATTAAAAAGTTCATTCCTTAACACAATGTTTCAAGTTAAACCTTTTGTGTCACCGCCCCCACCAACCACCACCTCCTAAA
TCCTGACAGCACTGTTTGCTTCCCAGCTAGACCTGTGTGAGAGGTGTCTGGAAATCATGCATGGTGTATTTGGGACTATATCAACCTATT
CTCCACACTTCAGACAACTGTCTGCACTCACGGCACACACACTTTGTATCATGCAGGCCACACTCAGAGCTAGTCAGTACATGAACAGTG
GTGCGGTGCCAGTCTGTGTCCGTTGTGATCACAGGCCTTGCTAGACCCTGATCATCTGGTTCTCCTCTCATTAAGCATCCCTAACCCCCA
GTCACACCTTCCTCTTACATACTGTTCCCCAATGGAGGCCCCTGGCATAGGGGACAGCCCTGGGCATCTTCCTTTGGTGTCTGGCTGTTT
TGTCAACTCTCATCCACTGGTGGCTCAGAGCCATAAGGTGGGTTGATTACACAATGCCTTGTACATGATATAGAGGCATCAAGCAAGTAA
AATTTGACAGAAATTTTAAAATATGAAGATGTATAGCTTTCCCAAGATGATGGTAAAACCCAGGTTAGTCATCAGTAACCTTCTCTATTA
TTATTATTTTTTAGAAACTTGGAATACTGTCGTCATGGCTAAGAGAACAAATCTGATAAATTGTGTAACCTAGTCTCTTCTCTACATGGT
GATGCATTTCAGCAATTATAAATTAATATAAATGACCAAAAGTAACTTAAAAGCATGAGATATTTGCTATTTCATTCATTGGGCACATAT
CAAATTATAATTTTGATTTTAAATGGTCACCCATGTATTTATTTGTTGCCAAGCAAGTAAAAAAATACCCTAACAAACCTGATGTGGGTG
GGAGGGGCATGTCAGTAAGTGGTGTGTTCAATGTGTTTGTTTCATATGGGCCCTTTCCAGGAGTTTGCAAACCTTGTCATACCCATATGC
AAAACTGTGTTTCCTTGCATTAAACCAGTGAAGTTTGGGTTCTCTTTTGTGCTATCAATCAGTTGTAAAATCAGAGCTGCTTATATATTC
TACTGGAATAACTGCATCTTCCACTCAGTCACTACAAAAAAGCATAGTTTCAGTTTGCATGAATTTTTTTTTTTTTCTTCAATGGCTGTG
CAGATAAGGATCCATTTCTGGGATAGAATTGTATTTTTTAAGTCATTTTTTTTTCTTGAAATGGATATGTACAAATAAAATAAATGGAAG

>323_323_4_ABCD3-AK5_ABCD3_chr1_94965170_ENST00000394233_AK5_chr1_77876666_ENST00000354567_length(amino acids)=735AA_BP=470
MAAFSKYLTARNSSLAGAAFLLLCLLHKRRRALGLHGKKSGKPPLQNNEKEGKKERAVVDKVFFSRLIQILKIMVPRTFCKETGYLVLIA
VMLVSRTYCDVWMIQNGTLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLYEEYLQAFTYYKMGNLDN
RIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTSAIGAQGPASMMAYLVVSGLFLTRLRRPIGKMTITEQKYEGEYRYVNS
RLITNSFTARITELMQVLKDLNHGKYERTMVSQQEKGIEGVQVIPLIPGAGEIIIADNIIKFDHVPLATPNGDVLIRDLNFEVRSGANVL
ICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTLGTLRDQVIYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREGG
WDSVQDWMDVLSGGEKQRMAFDADRDEDEVFYDISMAVDNKLFPNKEAAAGSSDLDPSMILDTGEIIDTGSDYEDQGDDQLNVFGEDTMG
GFMEDLRKCKIIFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIMERGDLVPSGIVLELLKEAMVASLGDTRG
FLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNRLLQRSRSSLPVDDTTKTIAKRLEAYYRASIPVIAYYETKTQLHKINAEGTP

--------------------------------------------------------------
>323_323_5_ABCD3-AK5_ABCD3_chr1_94965170_ENST00000454898_AK5_chr1_77876666_ENST00000344720_length(transcript)=3968nt_BP=1878nt
AGTAAGGTAGCCGCCGCCGCCGCCGCCGCCGCGTCCCCTCGCCGGCTCGCTGGTACCGGCAGTGCCATGGCGGCCTTCAGCAAGTACTTG
ACGGCGCGAAACTCCTCGCTGGCTGGTGCCGCGTTCCTGCTGCTCTGCCTGCTCCACAAGCGGCGCCGCGCCCTCGGCCTGCACGGGTAT
TTCATGGAAACTTGGAGAGAGAAAAGTGATGAAGTGATGGGAGAGCTGACTGATCATGTGACTCATTGTAAGAAAAGTGGAAAACCACCA
TTACAGAACAATGAGAAAGAGGGGAAAAAGGAGCGAGCTGTGGTGGACAAGGTGTTTTTCTCAAGGCTCATACAGATTCTGAAAATCATG
GTCCCTAGAACATTTTGTAAAGAGACAGGTTACTTGGTACTTATTGCTGTTATGCTGGTGTCTCGAACATATTGTGATGTTTGGATGATT
CAAAATGGGACACTAATTGAAAGTGGTATCATTGGTCGTAGCAGGAAAGATTTCAAGAGATACTTACTCAACTTCATCGCTGCCATGCCT
CTTATCTCTCTGGTTAATAACTTCTTGAAGTATGGGTTAAATGAGCTTAAACTGTGCTTCCGAGTAAGGCTCACTAAATACCTCTATGAG
GAGTATCTTCAAGCTTTCACATATTATAAAATGGGGAATCTGGACAACAGAATAGCTAATCCAGACCAGCTGCTTACACAAGATGTAGAA
AAATTTTGTAACAGTGTAGTCGATCTGTATTCAAATCTTAGTAAGCCATTTTTAGACATAGTTTTGTATATCTTTAAGTTAACGAGTGCA
ATTGGAGCTCAGGGCCCAGCGAGCATGATGGCCTACTTGGTTGTTTCTGGGCTATTCCTAACTCGACTTCGAAGACCCATTGGTAAGATG
ACAATAACTGAGCAAAAGTATGAAGGAGAATATAGATATGTTAATTCTCGGCTCATCACAAACAGTGAAGAAATTGCCTTTTACAATGGG
AATAAAAGAGAAAAGCAGACAGTCCACTCAGTCTTCCGAAAACTGGTGGAACACCTACATAATTTCATTTTGTTTCGGTTTTCAATGGGC
TTCATTGATAGTATTATTGCCAAATACCTTGCCACTGTTGTTGGTTACCTAGTTGTCAGTCGCCCTTTCTTAGATTTGTCTCATCCTCGA
CATCTCAAGAGTACACATTCGGAACTTCTAGAGGATTACTACCAAAGTGGAAGAATGCTTTTGCGAATGTCTCAAGCTCTGGGTCGAATA
GTTTTGGCTGGGCGTGAAATGACTAGATTGGCCGGTTTTACTGCTCGGATTACAGAATTAATGCAAGTACTGAAGGATTTAAATCATGGC
AAATATGAGCGCACAATGGTCTCACAACAGGAAAAGGGTATTGAAGGAGTACAAGTCATTCCCTTGATACCTGGTGCTGGAGAAATCATT
ATTGCAGATAACATTATAAAGTTTGATCATGTTCCTTTAGCAACGCCAAATGGAGATGTTTTGATCCGAGACCTTAATTTTGAAGTTCGA
TCTGGGGCTAATGTTCTAATTTGTGGTCCAAATGGCTGCGGAAAGAGTTCACTTTTCCGTGTTCTTGGTGAATTATGGCCTCTTTTTGGA
GGACGTCTAACTAAACCTGAAAGAGGAAAATTATTTTATGTTCCTCAGAGACCTTACATGACCCTTGGAACACTTCGAGATCAAGTGATA
TATCCAGATGGACGAGAAGATCAGAAAAGGAAGGGAATTTCTGACCTAGTACTGAAGGAATACTTAGACAATGTCCAGTTGGGTCATATC
CTTGAACGTGAAGGAGGCTGGGACAGTGTTCAGGATTGGATGGACGTACTCAGTGGTGGAGAAAAGCAAAGAATGGCGTTTGATGCCGAC
CGCGATGAGGATGAGGTGTTCTATGACATCAGCATGGCAGTTGACAACAAGTTATTTCCAAACAAAGAGGCTGCAGCAGGTTCAAGTGAC
CTTGATCCTTCGATGATATTGGACACTGGAGAGATCATTGATACAGGATCTGATTATGAAGATCAGGGTGATGACCAGTTAAATGTATTT
GGAGAGGACACTATGGGAGGTTTCATGGAAGATTTGAGAAAGTGTAAAATTATTTTCATAATTGGTGGTCCTGGCTCTGGCAAAGGCACA
CAGTGTGAAAAGCTGGTGGAAAAATATGGATTTACACATCTCTCAACTGGCGAGCTCCTGCGTGAGGAACTGGCATCAGAATCTGAAAGA
AGCAAATTGATCAGAGACATTATGGAACGTGGAGACCTGGTGCCCTCAGGCATCGTTTTGGAGCTCCTGAAGGAGGCCATGGTGGCCAGC
CTCGGGGACACCAGGGGCTTCCTGATTGACGGCTATCCTCGGGAGGTGAAGCAAGGGGAAGAGTTCGGACGCAGGATTGGAGACCCACAG
TTGGTGATCTGTATGGACTGCTCGGCAGACACCATGACCAACCGCCTTCTCCAAAGGAGCCGGAGCAGCCTGCCTGTGGACGACACCACC
AAGACCATCGCCAAGCGCCTAGAAGCCTACTACCGAGCGTCCATCCCCGTGATCGCCTACTACGAGACAAAAACACAGCTACACAAGATA
AATGCAGAGGGAACACCAGAGGACGTTTTTCTTCAACTCTGCACAGCTATTGACTCTATTTTCTGAAGGCAAAAATGCATGTTTGTTAGA
ATGGAAACAGAAAAACATTAAAAAGTTCATTCCTTAACACAATGTTTCAAGTTAAACCTTTTGTGTCACCGCCCCCACCAACCACCACCT
CCTAAATCCTGACAGCACTGTTTGCTTCCCAGCTAGACCTGTGTGAGAGGTGTCTGGAAATCATGCATGGTGTATTTGGGACTATATCAA
CCTATTCTCCACACTTCAGACAACTGTCTGCACTCACGGCACACACACTTTGTATCATGCAGGCCACACTCAGAGCTAGTCAGTACATGA
ACAGTGGTGCGGTGCCAGTCTGTGTCCGTTGTGATCACAGGCCTTGCTAGACCCTGATCATCTGGTTCTCCTCTCATTAAGCATCCCTAA
CCCCCAGTCACACCTTCCTCTTACATACTGTTCCCCAATGGAGGCCCCTGGCATAGGGGACAGCCCTGGGCATCTTCCTTTGGTGTCTGG
CTGTTTTGTCAACTCTCATCCACTGGTGGCTCAGAGCCATAAGGTGGGTTGATTACACAATGCCTTGTACATGATATAGAGGCATCAAGC
AAGTAAAATTTGACAGAAATTTTAAAATATGAAGATGTATAGCTTTCCCAAGATGATGGTAAAACCCAGGTTAGTCATCAGTAACCTTCT
CTATTATTATTATTTTTTAGAAACTTGGAATACTGTCGTCATGGCTAAGAGAACAAATCTGATAAATTGTGTAACCTAGTCTCTTCTCTA
CATGGTGATGCATTTCAGCAATTATAAATTAATATAAATGACCAAAAGTAACTTAAAAGCATGAGATATTTGCTATTTCATTCATTGGGC
ACATATCAAATTATAATTTTGATTTTAAATGGTCACCCATGTATTTATTTGTTGCCAAGCAAGTAAAAAAATACCCTAACAAACCTGATG
TGGGTGGGAGGGGCATGTCAGTAAGTGGTGTGTTCAATGTGTTTGTTTCATATGGGCCCTTTCCAGGAGTTTGCAAACCTTGTCATACCC
ATATGCAAAACTGTGTTTCCTTGCATTAAACCAGTGAAGTTTGGGTTCTCTTTTGTGCTATCAATCAGTTGTAAAATCAGAGCTGCTTAT
ATATTCTACTGGAATAACTGCATCTTCCACTCAGTCACTACAAAAAAGCATAGTTTCAGTTTGCATGAATTTTTTTTTTTTTCTTCAATG
GCTGTGCAGATAAGGATCCATTTCTGGGATAGAATTGTATTTTTTAAGTCATTTTTTTTTCTTGAAATGGATATGTACAAATAAAATAAA

>323_323_5_ABCD3-AK5_ABCD3_chr1_94965170_ENST00000454898_AK5_chr1_77876666_ENST00000344720_length(amino acids)=869AA_BP=604
MAAFSKYLTARNSSLAGAAFLLLCLLHKRRRALGLHGYFMETWREKSDEVMGELTDHVTHCKKSGKPPLQNNEKEGKKERAVVDKVFFSR
LIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWMIQNGTLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRV
RLTKYLYEEYLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTSAIGAQGPASMMAYLVVSGLFLTR
LRRPIGKMTITEQKYEGEYRYVNSRLITNSEEIAFYNGNKREKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSRP
FLDLSHPRHLKSTHSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLNHGKYERTMVSQQEKGIEGVQVIPL
IPGAGEIIIADNIIKFDHVPLATPNGDVLIRDLNFEVRSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTL
GTLRDQVIYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEKQRMAFDADRDEDEVFYDISMAVDNKLFPNK
EAAAGSSDLDPSMILDTGEIIDTGSDYEDQGDDQLNVFGEDTMGGFMEDLRKCKIIFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLRE
ELASESERSKLIRDIMERGDLVPSGIVLELLKEAMVASLGDTRGFLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNRLLQRSRS

--------------------------------------------------------------
>323_323_6_ABCD3-AK5_ABCD3_chr1_94965170_ENST00000454898_AK5_chr1_77876666_ENST00000354567_length(transcript)=3972nt_BP=1878nt
AGTAAGGTAGCCGCCGCCGCCGCCGCCGCCGCGTCCCCTCGCCGGCTCGCTGGTACCGGCAGTGCCATGGCGGCCTTCAGCAAGTACTTG
ACGGCGCGAAACTCCTCGCTGGCTGGTGCCGCGTTCCTGCTGCTCTGCCTGCTCCACAAGCGGCGCCGCGCCCTCGGCCTGCACGGGTAT
TTCATGGAAACTTGGAGAGAGAAAAGTGATGAAGTGATGGGAGAGCTGACTGATCATGTGACTCATTGTAAGAAAAGTGGAAAACCACCA
TTACAGAACAATGAGAAAGAGGGGAAAAAGGAGCGAGCTGTGGTGGACAAGGTGTTTTTCTCAAGGCTCATACAGATTCTGAAAATCATG
GTCCCTAGAACATTTTGTAAAGAGACAGGTTACTTGGTACTTATTGCTGTTATGCTGGTGTCTCGAACATATTGTGATGTTTGGATGATT
CAAAATGGGACACTAATTGAAAGTGGTATCATTGGTCGTAGCAGGAAAGATTTCAAGAGATACTTACTCAACTTCATCGCTGCCATGCCT
CTTATCTCTCTGGTTAATAACTTCTTGAAGTATGGGTTAAATGAGCTTAAACTGTGCTTCCGAGTAAGGCTCACTAAATACCTCTATGAG
GAGTATCTTCAAGCTTTCACATATTATAAAATGGGGAATCTGGACAACAGAATAGCTAATCCAGACCAGCTGCTTACACAAGATGTAGAA
AAATTTTGTAACAGTGTAGTCGATCTGTATTCAAATCTTAGTAAGCCATTTTTAGACATAGTTTTGTATATCTTTAAGTTAACGAGTGCA
ATTGGAGCTCAGGGCCCAGCGAGCATGATGGCCTACTTGGTTGTTTCTGGGCTATTCCTAACTCGACTTCGAAGACCCATTGGTAAGATG
ACAATAACTGAGCAAAAGTATGAAGGAGAATATAGATATGTTAATTCTCGGCTCATCACAAACAGTGAAGAAATTGCCTTTTACAATGGG
AATAAAAGAGAAAAGCAGACAGTCCACTCAGTCTTCCGAAAACTGGTGGAACACCTACATAATTTCATTTTGTTTCGGTTTTCAATGGGC
TTCATTGATAGTATTATTGCCAAATACCTTGCCACTGTTGTTGGTTACCTAGTTGTCAGTCGCCCTTTCTTAGATTTGTCTCATCCTCGA
CATCTCAAGAGTACACATTCGGAACTTCTAGAGGATTACTACCAAAGTGGAAGAATGCTTTTGCGAATGTCTCAAGCTCTGGGTCGAATA
GTTTTGGCTGGGCGTGAAATGACTAGATTGGCCGGTTTTACTGCTCGGATTACAGAATTAATGCAAGTACTGAAGGATTTAAATCATGGC
AAATATGAGCGCACAATGGTCTCACAACAGGAAAAGGGTATTGAAGGAGTACAAGTCATTCCCTTGATACCTGGTGCTGGAGAAATCATT
ATTGCAGATAACATTATAAAGTTTGATCATGTTCCTTTAGCAACGCCAAATGGAGATGTTTTGATCCGAGACCTTAATTTTGAAGTTCGA
TCTGGGGCTAATGTTCTAATTTGTGGTCCAAATGGCTGCGGAAAGAGTTCACTTTTCCGTGTTCTTGGTGAATTATGGCCTCTTTTTGGA
GGACGTCTAACTAAACCTGAAAGAGGAAAATTATTTTATGTTCCTCAGAGACCTTACATGACCCTTGGAACACTTCGAGATCAAGTGATA
TATCCAGATGGACGAGAAGATCAGAAAAGGAAGGGAATTTCTGACCTAGTACTGAAGGAATACTTAGACAATGTCCAGTTGGGTCATATC
CTTGAACGTGAAGGAGGCTGGGACAGTGTTCAGGATTGGATGGACGTACTCAGTGGTGGAGAAAAGCAAAGAATGGCGTTTGATGCCGAC
CGCGATGAGGATGAGGTGTTCTATGACATCAGCATGGCAGTTGACAACAAGTTATTTCCAAACAAAGAGGCTGCAGCAGGTTCAAGTGAC
CTTGATCCTTCGATGATATTGGACACTGGAGAGATCATTGATACAGGATCTGATTATGAAGATCAGGGTGATGACCAGTTAAATGTATTT
GGAGAGGACACTATGGGAGGTTTCATGGAAGATTTGAGAAAGTGTAAAATTATTTTCATAATTGGTGGTCCTGGCTCTGGCAAAGGCACA
CAGTGTGAAAAGCTGGTGGAAAAATATGGATTTACACATCTCTCAACTGGCGAGCTCCTGCGTGAGGAACTGGCATCAGAATCTGAAAGA
AGCAAATTGATCAGAGACATTATGGAACGTGGAGACCTGGTGCCCTCAGGCATCGTTTTGGAGCTCCTGAAGGAGGCCATGGTGGCCAGC
CTCGGGGACACCAGGGGCTTCCTGATTGACGGCTATCCTCGGGAGGTGAAGCAAGGGGAAGAGTTCGGACGCAGGATTGGAGACCCACAG
TTGGTGATCTGTATGGACTGCTCGGCAGACACCATGACCAACCGCCTTCTCCAAAGGAGCCGGAGCAGCCTGCCTGTGGACGACACCACC
AAGACCATCGCCAAGCGCCTAGAAGCCTACTACCGAGCGTCCATCCCCGTGATCGCCTACTACGAGACAAAAACACAGCTACACAAGATA
AATGCAGAGGGAACACCAGAGGACGTTTTTCTTCAACTCTGCACAGCTATTGACTCTATTTTCTGAAGGCAAAAATGCATGTTTGTTAGA
ATGGAAACAGAAAAACATTAAAAAGTTCATTCCTTAACACAATGTTTCAAGTTAAACCTTTTGTGTCACCGCCCCCACCAACCACCACCT
CCTAAATCCTGACAGCACTGTTTGCTTCCCAGCTAGACCTGTGTGAGAGGTGTCTGGAAATCATGCATGGTGTATTTGGGACTATATCAA
CCTATTCTCCACACTTCAGACAACTGTCTGCACTCACGGCACACACACTTTGTATCATGCAGGCCACACTCAGAGCTAGTCAGTACATGA
ACAGTGGTGCGGTGCCAGTCTGTGTCCGTTGTGATCACAGGCCTTGCTAGACCCTGATCATCTGGTTCTCCTCTCATTAAGCATCCCTAA
CCCCCAGTCACACCTTCCTCTTACATACTGTTCCCCAATGGAGGCCCCTGGCATAGGGGACAGCCCTGGGCATCTTCCTTTGGTGTCTGG
CTGTTTTGTCAACTCTCATCCACTGGTGGCTCAGAGCCATAAGGTGGGTTGATTACACAATGCCTTGTACATGATATAGAGGCATCAAGC
AAGTAAAATTTGACAGAAATTTTAAAATATGAAGATGTATAGCTTTCCCAAGATGATGGTAAAACCCAGGTTAGTCATCAGTAACCTTCT
CTATTATTATTATTTTTTAGAAACTTGGAATACTGTCGTCATGGCTAAGAGAACAAATCTGATAAATTGTGTAACCTAGTCTCTTCTCTA
CATGGTGATGCATTTCAGCAATTATAAATTAATATAAATGACCAAAAGTAACTTAAAAGCATGAGATATTTGCTATTTCATTCATTGGGC
ACATATCAAATTATAATTTTGATTTTAAATGGTCACCCATGTATTTATTTGTTGCCAAGCAAGTAAAAAAATACCCTAACAAACCTGATG
TGGGTGGGAGGGGCATGTCAGTAAGTGGTGTGTTCAATGTGTTTGTTTCATATGGGCCCTTTCCAGGAGTTTGCAAACCTTGTCATACCC
ATATGCAAAACTGTGTTTCCTTGCATTAAACCAGTGAAGTTTGGGTTCTCTTTTGTGCTATCAATCAGTTGTAAAATCAGAGCTGCTTAT
ATATTCTACTGGAATAACTGCATCTTCCACTCAGTCACTACAAAAAAGCATAGTTTCAGTTTGCATGAATTTTTTTTTTTTTCTTCAATG
GCTGTGCAGATAAGGATCCATTTCTGGGATAGAATTGTATTTTTTAAGTCATTTTTTTTTCTTGAAATGGATATGTACAAATAAAATAAA

>323_323_6_ABCD3-AK5_ABCD3_chr1_94965170_ENST00000454898_AK5_chr1_77876666_ENST00000354567_length(amino acids)=869AA_BP=604
MAAFSKYLTARNSSLAGAAFLLLCLLHKRRRALGLHGYFMETWREKSDEVMGELTDHVTHCKKSGKPPLQNNEKEGKKERAVVDKVFFSR
LIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWMIQNGTLIESGIIGRSRKDFKRYLLNFIAAMPLISLVNNFLKYGLNELKLCFRV
RLTKYLYEEYLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIVLYIFKLTSAIGAQGPASMMAYLVVSGLFLTR
LRRPIGKMTITEQKYEGEYRYVNSRLITNSEEIAFYNGNKREKQTVHSVFRKLVEHLHNFILFRFSMGFIDSIIAKYLATVVGYLVVSRP
FLDLSHPRHLKSTHSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARITELMQVLKDLNHGKYERTMVSQQEKGIEGVQVIPL
IPGAGEIIIADNIIKFDHVPLATPNGDVLIRDLNFEVRSGANVLICGPNGCGKSSLFRVLGELWPLFGGRLTKPERGKLFYVPQRPYMTL
GTLRDQVIYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGEKQRMAFDADRDEDEVFYDISMAVDNKLFPNK
EAAAGSSDLDPSMILDTGEIIDTGSDYEDQGDDQLNVFGEDTMGGFMEDLRKCKIIFIIGGPGSGKGTQCEKLVEKYGFTHLSTGELLRE
ELASESERSKLIRDIMERGDLVPSGIVLELLKEAMVASLGDTRGFLIDGYPREVKQGEEFGRRIGDPQLVICMDCSADTMTNRLLQRSRS

--------------------------------------------------------------
>323_323_7_ABCD3-AK5_ABCD3_chr1_94965170_ENST00000536817_AK5_chr1_77876666_ENST00000344720_length(transcript)=3857nt_BP=1767nt
TAAGGTAGCCGCCGCCGCCGCCGCCGCCGCGTCCCCTCGCCGGCTCGCTGGTACCGGCAGTGCCATGGCGGCCTTCAGCAAGTACTTGAC
GGCGCGAAACTCCTCGCTGGCTGGTGCCGCGTTCCTGCTGCTCTGCCTGCTCCACAAGCGGCGCCGCGCCCTCGGCCTGCACGGAAAGAG
GGGAAAAAGGAGCGAGCTGTGGTGGACAAGGTGTTTTTCTCAAGGCTCATACAGATTCTGAAAATCATGGTCCCTAGAACATTTTGTAAA
GAGACAGGTTACTTGGTACTTATTGCTGTTATGCTGGTGTCTCGAACATATTGTGATGTTTGGATGATTCAAAATGGGACACTAATTGAA
AGTGGTATCATTGGTCGTAGCAGGAAAGATTTCAAGAGATACTTACTCAACTTCATCGCTGCCATGCCTCTTATCTCTCTGGTTAATAAC
TTCTTGAAGTATGGGTTAAATGAGCTTAAACTGTGCTTCCGAGTAAGGCTCACTAAATACCTCTATGAGGAGTATCTTCAAGCTTTCACA
TATTATAAAATGGGGAATCTGGACAACAGAATAGCTAATCCAGACCAGCTGCTTACACAAGATGTAGAAAAATTTTGTAACAGTGTAGTC
GATCTGTATTCAAATCTTAGTAAGCCATTTTTAGACATAGTTTTGTATATCTTTAAGTTAACGAGTGCAATTGGAGCTCAGGGCCCAGCG
AGCATGATGGCCTACTTGGTTGTTTCTGGGCTATTCCTAACTCGACTTCGAAGACCCATTGGTAAGATGACAATAACTGAGCAAAAGTAT
GAAGGAGAATATAGATATGTTAATTCTCGGCTCATCACAAACAGTGAAGAAATTGCCTTTTACAATGGGAATAAAAGAGAAAAGCAGACA
GTCCACTCAGTCTTCCGAAAACTGGTGGAACACCTACATAATTTCATTTTGTTTCGGTTTTCAATGGGCTTCATTGATAGTATTATTGCC
AAATACCTTGCCACTGTTGTTGGTTACCTAGTTGTCAGTCGCCCTTTCTTAGATTTGTCTCATCCTCGACATCTCAAGAGTACACATTCG
GAACTTCTAGAGGATTACTACCAAAGTGGAAGAATGCTTTTGCGAATGTCTCAAGCTCTGGGTCGAATAGTTTTGGCTGGGCGTGAAATG
ACTAGATTGGCCGGTTTTACTGCTCGGATTACAGAATTAATGCAAGTACTGAAGGATTTAAATCATGGCAAATATGAGCGCACAATGGTC
TCACAACAGGAAAAGGGTATTGAAGGAGTACAAGTCATTCCCTTGATACCTGGTGCTGGAGAAATCATTATTGCAGATAACATTATAAAG
TTTGATCATGTTCCTTTAGCAACGCCAAATGGAGATGTTTTGATCCGAGACCTTAATTTTGAAGTTCGATCTGGGGCTAATGTTCTAATT
TGTGGTCCAAATGGCTGCGGAAAGAGTTCACTTTTCCGTGTTCTTGGTGAATTATGGCCTCTTTTTGGAGGACGTCTAACTAAACCTGAA
AGAGGAAAATTATTTTATGTTCCTCAGAGACCTTACATGACCCTTGGAACACTTCGAGATCAAGTGATATATCCAGATGGACGAGAAGAT
CAGAAAAGGAAGGGAATTTCTGACCTAGTACTGAAGGAATACTTAGACAATGTCCAGTTGGGTCATATCCTTGAACGTGAAGGAGGCTGG
GACAGTGTTCAGGATTGGATGGACGTACTCAGTGGTGGAGAAAAGCAAAGAATGGCGTTTGATGCCGACCGCGATGAGGATGAGGTGTTC
TATGACATCAGCATGGCAGTTGACAACAAGTTATTTCCAAACAAAGAGGCTGCAGCAGGTTCAAGTGACCTTGATCCTTCGATGATATTG
GACACTGGAGAGATCATTGATACAGGATCTGATTATGAAGATCAGGGTGATGACCAGTTAAATGTATTTGGAGAGGACACTATGGGAGGT
TTCATGGAAGATTTGAGAAAGTGTAAAATTATTTTCATAATTGGTGGTCCTGGCTCTGGCAAAGGCACACAGTGTGAAAAGCTGGTGGAA
AAATATGGATTTACACATCTCTCAACTGGCGAGCTCCTGCGTGAGGAACTGGCATCAGAATCTGAAAGAAGCAAATTGATCAGAGACATT
ATGGAACGTGGAGACCTGGTGCCCTCAGGCATCGTTTTGGAGCTCCTGAAGGAGGCCATGGTGGCCAGCCTCGGGGACACCAGGGGCTTC
CTGATTGACGGCTATCCTCGGGAGGTGAAGCAAGGGGAAGAGTTCGGACGCAGGATTGGAGACCCACAGTTGGTGATCTGTATGGACTGC
TCGGCAGACACCATGACCAACCGCCTTCTCCAAAGGAGCCGGAGCAGCCTGCCTGTGGACGACACCACCAAGACCATCGCCAAGCGCCTA
GAAGCCTACTACCGAGCGTCCATCCCCGTGATCGCCTACTACGAGACAAAAACACAGCTACACAAGATAAATGCAGAGGGAACACCAGAG
GACGTTTTTCTTCAACTCTGCACAGCTATTGACTCTATTTTCTGAAGGCAAAAATGCATGTTTGTTAGAATGGAAACAGAAAAACATTAA
AAAGTTCATTCCTTAACACAATGTTTCAAGTTAAACCTTTTGTGTCACCGCCCCCACCAACCACCACCTCCTAAATCCTGACAGCACTGT
TTGCTTCCCAGCTAGACCTGTGTGAGAGGTGTCTGGAAATCATGCATGGTGTATTTGGGACTATATCAACCTATTCTCCACACTTCAGAC
AACTGTCTGCACTCACGGCACACACACTTTGTATCATGCAGGCCACACTCAGAGCTAGTCAGTACATGAACAGTGGTGCGGTGCCAGTCT
GTGTCCGTTGTGATCACAGGCCTTGCTAGACCCTGATCATCTGGTTCTCCTCTCATTAAGCATCCCTAACCCCCAGTCACACCTTCCTCT
TACATACTGTTCCCCAATGGAGGCCCCTGGCATAGGGGACAGCCCTGGGCATCTTCCTTTGGTGTCTGGCTGTTTTGTCAACTCTCATCC
ACTGGTGGCTCAGAGCCATAAGGTGGGTTGATTACACAATGCCTTGTACATGATATAGAGGCATCAAGCAAGTAAAATTTGACAGAAATT
TTAAAATATGAAGATGTATAGCTTTCCCAAGATGATGGTAAAACCCAGGTTAGTCATCAGTAACCTTCTCTATTATTATTATTTTTTAGA
AACTTGGAATACTGTCGTCATGGCTAAGAGAACAAATCTGATAAATTGTGTAACCTAGTCTCTTCTCTACATGGTGATGCATTTCAGCAA
TTATAAATTAATATAAATGACCAAAAGTAACTTAAAAGCATGAGATATTTGCTATTTCATTCATTGGGCACATATCAAATTATAATTTTG
ATTTTAAATGGTCACCCATGTATTTATTTGTTGCCAAGCAAGTAAAAAAATACCCTAACAAACCTGATGTGGGTGGGAGGGGCATGTCAG
TAAGTGGTGTGTTCAATGTGTTTGTTTCATATGGGCCCTTTCCAGGAGTTTGCAAACCTTGTCATACCCATATGCAAAACTGTGTTTCCT
TGCATTAAACCAGTGAAGTTTGGGTTCTCTTTTGTGCTATCAATCAGTTGTAAAATCAGAGCTGCTTATATATTCTACTGGAATAACTGC
ATCTTCCACTCAGTCACTACAAAAAAGCATAGTTTCAGTTTGCATGAATTTTTTTTTTTTTCTTCAATGGCTGTGCAGATAAGGATCCAT

>323_323_7_ABCD3-AK5_ABCD3_chr1_94965170_ENST00000536817_AK5_chr1_77876666_ENST00000344720_length(amino acids)=810AA_BP=545
MPAPQAAPRPRPARKEGKKERAVVDKVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWMIQNGTLIESGIIGRSRKDFKRY
LLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLYEEYLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIV
LYIFKLTSAIGAQGPASMMAYLVVSGLFLTRLRRPIGKMTITEQKYEGEYRYVNSRLITNSEEIAFYNGNKREKQTVHSVFRKLVEHLHN
FILFRFSMGFIDSIIAKYLATVVGYLVVSRPFLDLSHPRHLKSTHSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARITELM
QVLKDLNHGKYERTMVSQQEKGIEGVQVIPLIPGAGEIIIADNIIKFDHVPLATPNGDVLIRDLNFEVRSGANVLICGPNGCGKSSLFRV
LGELWPLFGGRLTKPERGKLFYVPQRPYMTLGTLRDQVIYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGE
KQRMAFDADRDEDEVFYDISMAVDNKLFPNKEAAAGSSDLDPSMILDTGEIIDTGSDYEDQGDDQLNVFGEDTMGGFMEDLRKCKIIFII
GGPGSGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIMERGDLVPSGIVLELLKEAMVASLGDTRGFLIDGYPREVKQGEE
FGRRIGDPQLVICMDCSADTMTNRLLQRSRSSLPVDDTTKTIAKRLEAYYRASIPVIAYYETKTQLHKINAEGTPEDVFLQLCTAIDSIF

--------------------------------------------------------------
>323_323_8_ABCD3-AK5_ABCD3_chr1_94965170_ENST00000536817_AK5_chr1_77876666_ENST00000354567_length(transcript)=3861nt_BP=1767nt
TAAGGTAGCCGCCGCCGCCGCCGCCGCCGCGTCCCCTCGCCGGCTCGCTGGTACCGGCAGTGCCATGGCGGCCTTCAGCAAGTACTTGAC
GGCGCGAAACTCCTCGCTGGCTGGTGCCGCGTTCCTGCTGCTCTGCCTGCTCCACAAGCGGCGCCGCGCCCTCGGCCTGCACGGAAAGAG
GGGAAAAAGGAGCGAGCTGTGGTGGACAAGGTGTTTTTCTCAAGGCTCATACAGATTCTGAAAATCATGGTCCCTAGAACATTTTGTAAA
GAGACAGGTTACTTGGTACTTATTGCTGTTATGCTGGTGTCTCGAACATATTGTGATGTTTGGATGATTCAAAATGGGACACTAATTGAA
AGTGGTATCATTGGTCGTAGCAGGAAAGATTTCAAGAGATACTTACTCAACTTCATCGCTGCCATGCCTCTTATCTCTCTGGTTAATAAC
TTCTTGAAGTATGGGTTAAATGAGCTTAAACTGTGCTTCCGAGTAAGGCTCACTAAATACCTCTATGAGGAGTATCTTCAAGCTTTCACA
TATTATAAAATGGGGAATCTGGACAACAGAATAGCTAATCCAGACCAGCTGCTTACACAAGATGTAGAAAAATTTTGTAACAGTGTAGTC
GATCTGTATTCAAATCTTAGTAAGCCATTTTTAGACATAGTTTTGTATATCTTTAAGTTAACGAGTGCAATTGGAGCTCAGGGCCCAGCG
AGCATGATGGCCTACTTGGTTGTTTCTGGGCTATTCCTAACTCGACTTCGAAGACCCATTGGTAAGATGACAATAACTGAGCAAAAGTAT
GAAGGAGAATATAGATATGTTAATTCTCGGCTCATCACAAACAGTGAAGAAATTGCCTTTTACAATGGGAATAAAAGAGAAAAGCAGACA
GTCCACTCAGTCTTCCGAAAACTGGTGGAACACCTACATAATTTCATTTTGTTTCGGTTTTCAATGGGCTTCATTGATAGTATTATTGCC
AAATACCTTGCCACTGTTGTTGGTTACCTAGTTGTCAGTCGCCCTTTCTTAGATTTGTCTCATCCTCGACATCTCAAGAGTACACATTCG
GAACTTCTAGAGGATTACTACCAAAGTGGAAGAATGCTTTTGCGAATGTCTCAAGCTCTGGGTCGAATAGTTTTGGCTGGGCGTGAAATG
ACTAGATTGGCCGGTTTTACTGCTCGGATTACAGAATTAATGCAAGTACTGAAGGATTTAAATCATGGCAAATATGAGCGCACAATGGTC
TCACAACAGGAAAAGGGTATTGAAGGAGTACAAGTCATTCCCTTGATACCTGGTGCTGGAGAAATCATTATTGCAGATAACATTATAAAG
TTTGATCATGTTCCTTTAGCAACGCCAAATGGAGATGTTTTGATCCGAGACCTTAATTTTGAAGTTCGATCTGGGGCTAATGTTCTAATT
TGTGGTCCAAATGGCTGCGGAAAGAGTTCACTTTTCCGTGTTCTTGGTGAATTATGGCCTCTTTTTGGAGGACGTCTAACTAAACCTGAA
AGAGGAAAATTATTTTATGTTCCTCAGAGACCTTACATGACCCTTGGAACACTTCGAGATCAAGTGATATATCCAGATGGACGAGAAGAT
CAGAAAAGGAAGGGAATTTCTGACCTAGTACTGAAGGAATACTTAGACAATGTCCAGTTGGGTCATATCCTTGAACGTGAAGGAGGCTGG
GACAGTGTTCAGGATTGGATGGACGTACTCAGTGGTGGAGAAAAGCAAAGAATGGCGTTTGATGCCGACCGCGATGAGGATGAGGTGTTC
TATGACATCAGCATGGCAGTTGACAACAAGTTATTTCCAAACAAAGAGGCTGCAGCAGGTTCAAGTGACCTTGATCCTTCGATGATATTG
GACACTGGAGAGATCATTGATACAGGATCTGATTATGAAGATCAGGGTGATGACCAGTTAAATGTATTTGGAGAGGACACTATGGGAGGT
TTCATGGAAGATTTGAGAAAGTGTAAAATTATTTTCATAATTGGTGGTCCTGGCTCTGGCAAAGGCACACAGTGTGAAAAGCTGGTGGAA
AAATATGGATTTACACATCTCTCAACTGGCGAGCTCCTGCGTGAGGAACTGGCATCAGAATCTGAAAGAAGCAAATTGATCAGAGACATT
ATGGAACGTGGAGACCTGGTGCCCTCAGGCATCGTTTTGGAGCTCCTGAAGGAGGCCATGGTGGCCAGCCTCGGGGACACCAGGGGCTTC
CTGATTGACGGCTATCCTCGGGAGGTGAAGCAAGGGGAAGAGTTCGGACGCAGGATTGGAGACCCACAGTTGGTGATCTGTATGGACTGC
TCGGCAGACACCATGACCAACCGCCTTCTCCAAAGGAGCCGGAGCAGCCTGCCTGTGGACGACACCACCAAGACCATCGCCAAGCGCCTA
GAAGCCTACTACCGAGCGTCCATCCCCGTGATCGCCTACTACGAGACAAAAACACAGCTACACAAGATAAATGCAGAGGGAACACCAGAG
GACGTTTTTCTTCAACTCTGCACAGCTATTGACTCTATTTTCTGAAGGCAAAAATGCATGTTTGTTAGAATGGAAACAGAAAAACATTAA
AAAGTTCATTCCTTAACACAATGTTTCAAGTTAAACCTTTTGTGTCACCGCCCCCACCAACCACCACCTCCTAAATCCTGACAGCACTGT
TTGCTTCCCAGCTAGACCTGTGTGAGAGGTGTCTGGAAATCATGCATGGTGTATTTGGGACTATATCAACCTATTCTCCACACTTCAGAC
AACTGTCTGCACTCACGGCACACACACTTTGTATCATGCAGGCCACACTCAGAGCTAGTCAGTACATGAACAGTGGTGCGGTGCCAGTCT
GTGTCCGTTGTGATCACAGGCCTTGCTAGACCCTGATCATCTGGTTCTCCTCTCATTAAGCATCCCTAACCCCCAGTCACACCTTCCTCT
TACATACTGTTCCCCAATGGAGGCCCCTGGCATAGGGGACAGCCCTGGGCATCTTCCTTTGGTGTCTGGCTGTTTTGTCAACTCTCATCC
ACTGGTGGCTCAGAGCCATAAGGTGGGTTGATTACACAATGCCTTGTACATGATATAGAGGCATCAAGCAAGTAAAATTTGACAGAAATT
TTAAAATATGAAGATGTATAGCTTTCCCAAGATGATGGTAAAACCCAGGTTAGTCATCAGTAACCTTCTCTATTATTATTATTTTTTAGA
AACTTGGAATACTGTCGTCATGGCTAAGAGAACAAATCTGATAAATTGTGTAACCTAGTCTCTTCTCTACATGGTGATGCATTTCAGCAA
TTATAAATTAATATAAATGACCAAAAGTAACTTAAAAGCATGAGATATTTGCTATTTCATTCATTGGGCACATATCAAATTATAATTTTG
ATTTTAAATGGTCACCCATGTATTTATTTGTTGCCAAGCAAGTAAAAAAATACCCTAACAAACCTGATGTGGGTGGGAGGGGCATGTCAG
TAAGTGGTGTGTTCAATGTGTTTGTTTCATATGGGCCCTTTCCAGGAGTTTGCAAACCTTGTCATACCCATATGCAAAACTGTGTTTCCT
TGCATTAAACCAGTGAAGTTTGGGTTCTCTTTTGTGCTATCAATCAGTTGTAAAATCAGAGCTGCTTATATATTCTACTGGAATAACTGC
ATCTTCCACTCAGTCACTACAAAAAAGCATAGTTTCAGTTTGCATGAATTTTTTTTTTTTTCTTCAATGGCTGTGCAGATAAGGATCCAT

>323_323_8_ABCD3-AK5_ABCD3_chr1_94965170_ENST00000536817_AK5_chr1_77876666_ENST00000354567_length(amino acids)=810AA_BP=545
MPAPQAAPRPRPARKEGKKERAVVDKVFFSRLIQILKIMVPRTFCKETGYLVLIAVMLVSRTYCDVWMIQNGTLIESGIIGRSRKDFKRY
LLNFIAAMPLISLVNNFLKYGLNELKLCFRVRLTKYLYEEYLQAFTYYKMGNLDNRIANPDQLLTQDVEKFCNSVVDLYSNLSKPFLDIV
LYIFKLTSAIGAQGPASMMAYLVVSGLFLTRLRRPIGKMTITEQKYEGEYRYVNSRLITNSEEIAFYNGNKREKQTVHSVFRKLVEHLHN
FILFRFSMGFIDSIIAKYLATVVGYLVVSRPFLDLSHPRHLKSTHSELLEDYYQSGRMLLRMSQALGRIVLAGREMTRLAGFTARITELM
QVLKDLNHGKYERTMVSQQEKGIEGVQVIPLIPGAGEIIIADNIIKFDHVPLATPNGDVLIRDLNFEVRSGANVLICGPNGCGKSSLFRV
LGELWPLFGGRLTKPERGKLFYVPQRPYMTLGTLRDQVIYPDGREDQKRKGISDLVLKEYLDNVQLGHILEREGGWDSVQDWMDVLSGGE
KQRMAFDADRDEDEVFYDISMAVDNKLFPNKEAAAGSSDLDPSMILDTGEIIDTGSDYEDQGDDQLNVFGEDTMGGFMEDLRKCKIIFII
GGPGSGKGTQCEKLVEKYGFTHLSTGELLREELASESERSKLIRDIMERGDLVPSGIVLELLKEAMVASLGDTRGFLIDGYPREVKQGEE
FGRRIGDPQLVICMDCSADTMTNRLLQRSRSSLPVDDTTKTIAKRLEAYYRASIPVIAYYETKTQLHKINAEGTPEDVFLQLCTAIDSIF

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Fusion Gene PPI Analysis for ABCD3-AK5


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneABCD3chr1:94965170chr1:77876666ENST00000370214-20231_199580.0660.0PEX19
HgeneABCD3chr1:94965170chr1:77876666ENST00000394233-16191_199470.0550.0PEX19


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneABCD3chr1:94965170chr1:77876666ENST00000315713-191_1990.0237.0PEX19


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ABCD3-AK5


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ABCD3-AK5


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneABCD3C0009402Colorectal Carcinoma1CTD_human
HgeneABCD3C0009404Colorectal Neoplasms1CTD_human
HgeneABCD3C0043459Zellweger Syndrome1CTD_human
HgeneABCD3C0751594Zellweger-Like Syndrome1CTD_human
HgeneABCD3C3658299Zellweger Spectrum1CTD_human
HgeneABCD3C4225390BILE ACID SYNTHESIS DEFECT, CONGENITAL, 51CTD_human;GENOMICS_ENGLAND
TgeneC0236733Amphetamine-Related Disorders1CTD_human
TgeneC0236804Amphetamine Addiction1CTD_human
TgeneC0236807Amphetamine Abuse1CTD_human