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in Kim Lab

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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:FAM108C1-SCAPER (FusionGDB2 ID:HG58489TG49855)

Fusion Gene Summary for FAM108C1-SCAPER

check button Fusion gene summary
Fusion gene informationFusion gene name: FAM108C1-SCAPER
Fusion gene ID: hg58489tg49855
HgeneTgene
Gene symbol

FAM108C1

SCAPER

Gene ID

58489

49855

Gene nameabhydrolase domain containing 17C, depalmitoylaseS-phase cyclin A associated protein in the ER
SynonymsFAM108C1IDDRP|MSTP063|ZNF291|Zfp291
Cytomap('ABHD17C','FAM108C1')('SCAPER','SCAPER')

15q25.1

15q24.3

Type of geneprotein-codingprotein-coding
Descriptionalpha/beta hydrolase domain-containing protein 17Cabhydrolase domain containing 17Cabhydrolase domain-containing protein 17Cabhydrolase domain-containing protein FAM108C1family with sequence similarity 108, member C1protein ABHD17CS phase cyclin A-associated protein in the endoplasmic reticulumzinc finger protein 291
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000559506, ENST00000258884, 
ENST00000560609, ENST00000558464, 
Fusion gene scores* DoF score4 X 3 X 4=4819 X 17 X 8=2584
# samples 421
** MAII scorelog2(4/48*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(21/2584*10)=-3.6211448370278
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: FAM108C1 [Title/Abstract] AND SCAPER [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointABHD17C(81042033)-SCAPER(76763676), # samples:1
FAM108C1(81042033)-SCAPER(76763676), # samples:1
FAM108C1(80988360)-SCAPER(77176217), # samples:1
Anticipated loss of major functional domain due to fusion event.ABHD17C-SCAPER seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ABHD17C-SCAPER seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ABHD17C-SCAPER seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ABHD17C-SCAPER seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ABHD17C (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across SCAPER (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LGGTCGA-DU-A7TCABHD17Cchr15

81042033

+SCAPERchr15

76763676

-
ChimerDB4LGGTCGA-DU-A7TC-01AFAM108C1chr15

81042033

-SCAPERchr15

76763676

-
ChimerDB4SKCMTCGA-GN-A26A-06AFAM108C1chr15

80988360

-SCAPERchr15

77176217

-


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Fusion Gene ORF analysis for FAM108C1-SCAPER

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000559506ENST00000324767ABHD17Cchr15

81042033

+SCAPERchr15

76763676

-
3UTR-3CDSENST00000559506ENST00000538941ABHD17Cchr15

81042033

+SCAPERchr15

76763676

-
3UTR-3CDSENST00000559506ENST00000563290ABHD17Cchr15

81042033

+SCAPERchr15

76763676

-
3UTR-intronENST00000559506ENST00000562890ABHD17Cchr15

81042033

+SCAPERchr15

76763676

-
5CDS-intronENST00000258884ENST00000562890ABHD17Cchr15

81042033

+SCAPERchr15

76763676

-
5CDS-intronENST00000560609ENST00000562890ABHD17Cchr15

81042033

+SCAPERchr15

76763676

-
In-frameENST00000258884ENST00000324767ABHD17Cchr15

81042033

+SCAPERchr15

76763676

-
In-frameENST00000258884ENST00000538941ABHD17Cchr15

81042033

+SCAPERchr15

76763676

-
In-frameENST00000258884ENST00000563290ABHD17Cchr15

81042033

+SCAPERchr15

76763676

-
In-frameENST00000560609ENST00000324767ABHD17Cchr15

81042033

+SCAPERchr15

76763676

-
In-frameENST00000560609ENST00000538941ABHD17Cchr15

81042033

+SCAPERchr15

76763676

-
In-frameENST00000560609ENST00000563290ABHD17Cchr15

81042033

+SCAPERchr15

76763676

-
intron-3CDSENST00000558464ENST00000324767ABHD17Cchr15

81042033

+SCAPERchr15

76763676

-
intron-3CDSENST00000558464ENST00000538941ABHD17Cchr15

81042033

+SCAPERchr15

76763676

-
intron-3CDSENST00000558464ENST00000563290ABHD17Cchr15

81042033

+SCAPERchr15

76763676

-
intron-intronENST00000558464ENST00000562890ABHD17Cchr15

81042033

+SCAPERchr15

76763676

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000560609ABHD17Cchr1581042033+ENST00000538941SCAPERchr1576763676-1955258671506479
ENST00000560609ABHD17Cchr1581042033+ENST00000563290SCAPERchr1576763676-1955258671506479
ENST00000560609ABHD17Cchr1581042033+ENST00000324767SCAPERchr1576763676-1952258671506479
ENST00000258884ABHD17Cchr1581042033+ENST00000538941SCAPERchr1576763676-2594897102145711
ENST00000258884ABHD17Cchr1581042033+ENST00000563290SCAPERchr1576763676-2594897102145711
ENST00000258884ABHD17Cchr1581042033+ENST00000324767SCAPERchr1576763676-2591897102145711

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000560609ENST00000538941ABHD17Cchr1581042033+SCAPERchr1576763676-0.0003410710.99965894
ENST00000560609ENST00000563290ABHD17Cchr1581042033+SCAPERchr1576763676-0.0003410710.99965894
ENST00000560609ENST00000324767ABHD17Cchr1581042033+SCAPERchr1576763676-0.0003504410.9996495
ENST00000258884ENST00000538941ABHD17Cchr1581042033+SCAPERchr1576763676-0.0020538780.9979461
ENST00000258884ENST00000563290ABHD17Cchr1581042033+SCAPERchr1576763676-0.0020538780.9979461
ENST00000258884ENST00000324767ABHD17Cchr1581042033+SCAPERchr1576763676-0.0021070980.9978929

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Fusion Genomic Features for FAM108C1-SCAPER


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for FAM108C1-SCAPER


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/:81042033/:76763676)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneABHD17Cchr15:81042033chr15:76763676ENST00000258884+2352_86256330.0Compositional biasNote=Ala-rich
TgeneSCAPERchr15:81042033chr15:76763676ENST000005389412332792_8167381155.0Zinc fingerNote=C2H2-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneABHD17Cchr15:81042033chr15:76763676ENST00000558464+1352_860296.0Compositional biasNote=Ala-rich
TgeneSCAPERchr15:81042033chr15:76763676ENST000003247672231395_7709841401.0Compositional biasNote=Glu-rich
TgeneSCAPERchr15:81042033chr15:76763676ENST000005389412332395_7707381155.0Compositional biasNote=Glu-rich
TgeneSCAPERchr15:81042033chr15:76763676ENST000005632902332395_7709841401.0Compositional biasNote=Glu-rich
TgeneSCAPERchr15:81042033chr15:76763676ENST000003247672231792_8169841401.0Zinc fingerNote=C2H2-type
TgeneSCAPERchr15:81042033chr15:76763676ENST000005632902332792_8169841401.0Zinc fingerNote=C2H2-type


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Fusion Gene Sequence for FAM108C1-SCAPER


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>411_411_1_ABHD17C-SCAPER_ABHD17C_chr15_81042033_ENST00000258884_SCAPER_chr15_76763676_ENST00000324767_length(transcript)=2591nt_BP=897nt
GGCGGGCGGGCTGCAGCCGCCCTCCGCGCTCGCCTGCCAGCTCCCTCGCCGCGCGTCCGTCCTCCGTCCTCCCGGGCCAGCCAGCCAGCC
AGCCAGCCGGGCCGGCGGCGGGCACCAGGCCGTCCCGATGCCCGAGCCAGGCCCCAGGATGAACGGCTTCTCGCTGGGTGAGCTGTGCTG
GCTCTTCTGCTGCCCGCCCTGCCCGAGCCGCATCGCCGCCAAGCTGGCCTTCCTGCCGCCCGAGCCCACCTACACGGTGCTGGCGCCGGA
GCAGCGCGGCGCCGGCGCGTCCGCCCCGGCCCCGGCCCAGGCTACCGCCGCCGCCGCCGCGGCCCAGCCGGCACCGCAGCAGCCCGAGGA
GGGCGCGGGCGCGGGGCCCGGTGCGTGCAGCCTGCACCTCAGCGAGCGCGCCGACTGGCAGTACTCGCAGCGCGAGCTGGACGCCGTCGA
GGTCTTCTTCTCGCGCACGGCCCGGGACAACCGGCTCGGCTGCATGTTCGTGCGCTGCGCGCCCTCCAGCCGCTACACGCTGCTCTTCTC
GCACGGCAACGCCGTGGACCTGGGCCAGATGTGCAGCTTCTACATTGGCCTCGGCTCCCGCATCAACTGCAACATCTTCTCCTACGACTA
CTCGGGATACGGCGTCAGCTCGGGCAAGCCCTCCGAGAAGAACCTCTACGCCGACATCGACGCCGCGTGGCAGGCGCTGCGCACCCGGTA
TGGCGTGAGTCCCGAGAACATTATCCTCTATGGTCAGAGCATTGGGACTGTCCCCACGGTAGACTTGGCCTCGAGGTATGAATGCGCAGC
GGTAATTCTCCATTCCCCTCTGATGTCTGGTTTGCGTGTGGCTTTTCCGGATACCAGGAAAACATACTGCTTTGATGCTTTCCCCAGGTC
TCTCTGCAATGCAATCAATGTTTACAACCTCACCTGCAATAACTGTTCAGAAAACTGCAGTGATGTTCTGTTTAGTAACAAGATTACCTT
CTTAATGGACCTCCTGATACACCAGTTGACGGTTTATGTTCCAGATGAAAATAATACTATTTTGGGGAGAAATACAAATAAACAAGTTTT
TGAAGGCTTGACAACTGGACTTCTCAAAGTCAGTGCTGTGGTTTTGGGCTGCCTGATTGCCAATCGACCAGATGGAAACTGCCAGCCAGC
TACCCCAAAAATACCAACACAGGAAATGAAAAACAAACCCTCACAAGGTGATCCTTTTAACAATCGAGTTCAGGACCTTATCAGCTACGT
GGTGAACATGGGTCTGATTGACAAACTGTGTGCCTGCTTCCTCTCGGTGCAAGGCCCAGTGGATGAGAATCCCAAGATGGCCATATTTCT
GCAGCATGCCGCAGGACTCTTACATGCAATGTGTACACTGTGCTTTGCTGTCACTGGAAGGTCATACAGCATATTTGACAATAATCGCCA
GGATCCCACAGGGCTGACAGCTGCTCTTCAGGCAACCGACCTGGCTGGAGTTCTTCATATGCTCTACTGTGTCCTCTTCCATGGCACCAT
CTTGGACCCCAGCACTGCCAGTCCCAAGGAGAATTACACTCAAAATACCATCCAAGTGGCCATTCAGAGTTTACGTTTCTTCAACAGCTT
TGCAGCTCTTCATCTGCCTGCTTTTCAGTCTATTGTAGGGGCAGAGGGCTTGTCCCTTGCATTCCGGCACATGGCCAGCTCCCTGCTGGG
CCACTGCAGCCAAGTCTCCTGTGAAAGCCTCCTTCATGAGGTCATCGTCTGTGTGGGCTACTTCACTGTCAACCACCCAGATAACCAGGT
GATCGTGCAGTCCGGCCGCCACCCCACAGTGCTGCAGAAGCTCTGCCAGTTGCCCTTCCAGTATTTCAGTGACCCACGGCTGATCAAAGT
ACTGTTCCCTTCACTTATCGCTGCTTGTTACAACAACCATCAGAACAAGATCATTCTGGAGCAAGAGATGAGCTGTGTTTTACTGGCCAC
TTTCATTCAGGATTTGGCACAGACTCCAGGTCAAGCGGAAAACCAGCCTTACCAACCCAAAGGGAAATGCCTTGGTTCCCAAGACTATCT
TGAGCTGGCTAACAGATTTCCTCAGCAGGCCTGGGAAGAAGCTCGACAGTTTTTCTTGAAAAAAGAGAAAAAATAAATGTTTTGGTTGAT
TCTGTATTTGAGTACCCTTGTTAATATTTTAAATTGTCCAAACAAACATTCTAATTGTTCCTTAAGAACTCATTTTCCCATGTTTATACT
CTTCCCACACTGTAGATATGGCATGTACTTTACACTATTTATAATGACTGTAGATACTTGAATGTTCTACTTGCTAATTTTGCAAGTTGA
GTTTATTTCATTTATGCAGAGTATCTTGGAGTTTGGTAATTTCCATCTTATGATAATATATACTTTGCATTTGTGATATGGGTGAAAGGA
GACATAAAATTAGCAAGTCTGTTTTGTTCTTGTAATAAAGTAACTTATTCTGTTTTCATTGTTGACTTTTCATGTTAAGGAAATACGAAT

>411_411_1_ABHD17C-SCAPER_ABHD17C_chr15_81042033_ENST00000258884_SCAPER_chr15_76763676_ENST00000324767_length(amino acids)=711AA_BP=295
MQPPSALACQLPRRASVLRPPGPASQPASRAGGGHQAVPMPEPGPRMNGFSLGELCWLFCCPPCPSRIAAKLAFLPPEPTYTVLAPEQRG
AGASAPAPAQATAAAAAAQPAPQQPEEGAGAGPGACSLHLSERADWQYSQRELDAVEVFFSRTARDNRLGCMFVRCAPSSRYTLLFSHGN
AVDLGQMCSFYIGLGSRINCNIFSYDYSGYGVSSGKPSEKNLYADIDAAWQALRTRYGVSPENIILYGQSIGTVPTVDLASRYECAAVIL
HSPLMSGLRVAFPDTRKTYCFDAFPRSLCNAINVYNLTCNNCSENCSDVLFSNKITFLMDLLIHQLTVYVPDENNTILGRNTNKQVFEGL
TTGLLKVSAVVLGCLIANRPDGNCQPATPKIPTQEMKNKPSQGDPFNNRVQDLISYVVNMGLIDKLCACFLSVQGPVDENPKMAIFLQHA
AGLLHAMCTLCFAVTGRSYSIFDNNRQDPTGLTAALQATDLAGVLHMLYCVLFHGTILDPSTASPKENYTQNTIQVAIQSLRFFNSFAAL
HLPAFQSIVGAEGLSLAFRHMASSLLGHCSQVSCESLLHEVIVCVGYFTVNHPDNQVIVQSGRHPTVLQKLCQLPFQYFSDPRLIKVLFP

--------------------------------------------------------------
>411_411_2_ABHD17C-SCAPER_ABHD17C_chr15_81042033_ENST00000258884_SCAPER_chr15_76763676_ENST00000538941_length(transcript)=2594nt_BP=897nt
GGCGGGCGGGCTGCAGCCGCCCTCCGCGCTCGCCTGCCAGCTCCCTCGCCGCGCGTCCGTCCTCCGTCCTCCCGGGCCAGCCAGCCAGCC
AGCCAGCCGGGCCGGCGGCGGGCACCAGGCCGTCCCGATGCCCGAGCCAGGCCCCAGGATGAACGGCTTCTCGCTGGGTGAGCTGTGCTG
GCTCTTCTGCTGCCCGCCCTGCCCGAGCCGCATCGCCGCCAAGCTGGCCTTCCTGCCGCCCGAGCCCACCTACACGGTGCTGGCGCCGGA
GCAGCGCGGCGCCGGCGCGTCCGCCCCGGCCCCGGCCCAGGCTACCGCCGCCGCCGCCGCGGCCCAGCCGGCACCGCAGCAGCCCGAGGA
GGGCGCGGGCGCGGGGCCCGGTGCGTGCAGCCTGCACCTCAGCGAGCGCGCCGACTGGCAGTACTCGCAGCGCGAGCTGGACGCCGTCGA
GGTCTTCTTCTCGCGCACGGCCCGGGACAACCGGCTCGGCTGCATGTTCGTGCGCTGCGCGCCCTCCAGCCGCTACACGCTGCTCTTCTC
GCACGGCAACGCCGTGGACCTGGGCCAGATGTGCAGCTTCTACATTGGCCTCGGCTCCCGCATCAACTGCAACATCTTCTCCTACGACTA
CTCGGGATACGGCGTCAGCTCGGGCAAGCCCTCCGAGAAGAACCTCTACGCCGACATCGACGCCGCGTGGCAGGCGCTGCGCACCCGGTA
TGGCGTGAGTCCCGAGAACATTATCCTCTATGGTCAGAGCATTGGGACTGTCCCCACGGTAGACTTGGCCTCGAGGTATGAATGCGCAGC
GGTAATTCTCCATTCCCCTCTGATGTCTGGTTTGCGTGTGGCTTTTCCGGATACCAGGAAAACATACTGCTTTGATGCTTTCCCCAGGTC
TCTCTGCAATGCAATCAATGTTTACAACCTCACCTGCAATAACTGTTCAGAAAACTGCAGTGATGTTCTGTTTAGTAACAAGATTACCTT
CTTAATGGACCTCCTGATACACCAGTTGACGGTTTATGTTCCAGATGAAAATAATACTATTTTGGGGAGAAATACAAATAAACAAGTTTT
TGAAGGCTTGACAACTGGACTTCTCAAAGTCAGTGCTGTGGTTTTGGGCTGCCTGATTGCCAATCGACCAGATGGAAACTGCCAGCCAGC
TACCCCAAAAATACCAACACAGGAAATGAAAAACAAACCCTCACAAGGTGATCCTTTTAACAATCGAGTTCAGGACCTTATCAGCTACGT
GGTGAACATGGGTCTGATTGACAAACTGTGTGCCTGCTTCCTCTCGGTGCAAGGCCCAGTGGATGAGAATCCCAAGATGGCCATATTTCT
GCAGCATGCCGCAGGACTCTTACATGCAATGTGTACACTGTGCTTTGCTGTCACTGGAAGGTCATACAGCATATTTGACAATAATCGCCA
GGATCCCACAGGGCTGACAGCTGCTCTTCAGGCAACCGACCTGGCTGGAGTTCTTCATATGCTCTACTGTGTCCTCTTCCATGGCACCAT
CTTGGACCCCAGCACTGCCAGTCCCAAGGAGAATTACACTCAAAATACCATCCAAGTGGCCATTCAGAGTTTACGTTTCTTCAACAGCTT
TGCAGCTCTTCATCTGCCTGCTTTTCAGTCTATTGTAGGGGCAGAGGGCTTGTCCCTTGCATTCCGGCACATGGCCAGCTCCCTGCTGGG
CCACTGCAGCCAAGTCTCCTGTGAAAGCCTCCTTCATGAGGTCATCGTCTGTGTGGGCTACTTCACTGTCAACCACCCAGATAACCAGGT
GATCGTGCAGTCCGGCCGCCACCCCACAGTGCTGCAGAAGCTCTGCCAGTTGCCCTTCCAGTATTTCAGTGACCCACGGCTGATCAAAGT
ACTGTTCCCTTCACTTATCGCTGCTTGTTACAACAACCATCAGAACAAGATCATTCTGGAGCAAGAGATGAGCTGTGTTTTACTGGCCAC
TTTCATTCAGGATTTGGCACAGACTCCAGGTCAAGCGGAAAACCAGCCTTACCAACCCAAAGGGAAATGCCTTGGTTCCCAAGACTATCT
TGAGCTGGCTAACAGATTTCCTCAGCAGGCCTGGGAAGAAGCTCGACAGTTTTTCTTGAAAAAAGAGAAAAAATAAATGTTTTGGTTGAT
TCTGTATTTGAGTACCCTTGTTAATATTTTAAATTGTCCAAACAAACATTCTAATTGTTCCTTAAGAACTCATTTTCCCATGTTTATACT
CTTCCCACACTGTAGATATGGCATGTACTTTACACTATTTATAATGACTGTAGATACTTGAATGTTCTACTTGCTAATTTTGCAAGTTGA
GTTTATTTCATTTATGCAGAGTATCTTGGAGTTTGGTAATTTCCATCTTATGATAATATATACTTTGCATTTGTGATATGGGTGAAAGGA
GACATAAAATTAGCAAGTCTGTTTTGTTCTTGTAATAAAGTAACTTATTCTGTTTTCATTGTTGACTTTTCATGTTAAGGAAATACGAAT

>411_411_2_ABHD17C-SCAPER_ABHD17C_chr15_81042033_ENST00000258884_SCAPER_chr15_76763676_ENST00000538941_length(amino acids)=711AA_BP=295
MQPPSALACQLPRRASVLRPPGPASQPASRAGGGHQAVPMPEPGPRMNGFSLGELCWLFCCPPCPSRIAAKLAFLPPEPTYTVLAPEQRG
AGASAPAPAQATAAAAAAQPAPQQPEEGAGAGPGACSLHLSERADWQYSQRELDAVEVFFSRTARDNRLGCMFVRCAPSSRYTLLFSHGN
AVDLGQMCSFYIGLGSRINCNIFSYDYSGYGVSSGKPSEKNLYADIDAAWQALRTRYGVSPENIILYGQSIGTVPTVDLASRYECAAVIL
HSPLMSGLRVAFPDTRKTYCFDAFPRSLCNAINVYNLTCNNCSENCSDVLFSNKITFLMDLLIHQLTVYVPDENNTILGRNTNKQVFEGL
TTGLLKVSAVVLGCLIANRPDGNCQPATPKIPTQEMKNKPSQGDPFNNRVQDLISYVVNMGLIDKLCACFLSVQGPVDENPKMAIFLQHA
AGLLHAMCTLCFAVTGRSYSIFDNNRQDPTGLTAALQATDLAGVLHMLYCVLFHGTILDPSTASPKENYTQNTIQVAIQSLRFFNSFAAL
HLPAFQSIVGAEGLSLAFRHMASSLLGHCSQVSCESLLHEVIVCVGYFTVNHPDNQVIVQSGRHPTVLQKLCQLPFQYFSDPRLIKVLFP

--------------------------------------------------------------
>411_411_3_ABHD17C-SCAPER_ABHD17C_chr15_81042033_ENST00000258884_SCAPER_chr15_76763676_ENST00000563290_length(transcript)=2594nt_BP=897nt
GGCGGGCGGGCTGCAGCCGCCCTCCGCGCTCGCCTGCCAGCTCCCTCGCCGCGCGTCCGTCCTCCGTCCTCCCGGGCCAGCCAGCCAGCC
AGCCAGCCGGGCCGGCGGCGGGCACCAGGCCGTCCCGATGCCCGAGCCAGGCCCCAGGATGAACGGCTTCTCGCTGGGTGAGCTGTGCTG
GCTCTTCTGCTGCCCGCCCTGCCCGAGCCGCATCGCCGCCAAGCTGGCCTTCCTGCCGCCCGAGCCCACCTACACGGTGCTGGCGCCGGA
GCAGCGCGGCGCCGGCGCGTCCGCCCCGGCCCCGGCCCAGGCTACCGCCGCCGCCGCCGCGGCCCAGCCGGCACCGCAGCAGCCCGAGGA
GGGCGCGGGCGCGGGGCCCGGTGCGTGCAGCCTGCACCTCAGCGAGCGCGCCGACTGGCAGTACTCGCAGCGCGAGCTGGACGCCGTCGA
GGTCTTCTTCTCGCGCACGGCCCGGGACAACCGGCTCGGCTGCATGTTCGTGCGCTGCGCGCCCTCCAGCCGCTACACGCTGCTCTTCTC
GCACGGCAACGCCGTGGACCTGGGCCAGATGTGCAGCTTCTACATTGGCCTCGGCTCCCGCATCAACTGCAACATCTTCTCCTACGACTA
CTCGGGATACGGCGTCAGCTCGGGCAAGCCCTCCGAGAAGAACCTCTACGCCGACATCGACGCCGCGTGGCAGGCGCTGCGCACCCGGTA
TGGCGTGAGTCCCGAGAACATTATCCTCTATGGTCAGAGCATTGGGACTGTCCCCACGGTAGACTTGGCCTCGAGGTATGAATGCGCAGC
GGTAATTCTCCATTCCCCTCTGATGTCTGGTTTGCGTGTGGCTTTTCCGGATACCAGGAAAACATACTGCTTTGATGCTTTCCCCAGGTC
TCTCTGCAATGCAATCAATGTTTACAACCTCACCTGCAATAACTGTTCAGAAAACTGCAGTGATGTTCTGTTTAGTAACAAGATTACCTT
CTTAATGGACCTCCTGATACACCAGTTGACGGTTTATGTTCCAGATGAAAATAATACTATTTTGGGGAGAAATACAAATAAACAAGTTTT
TGAAGGCTTGACAACTGGACTTCTCAAAGTCAGTGCTGTGGTTTTGGGCTGCCTGATTGCCAATCGACCAGATGGAAACTGCCAGCCAGC
TACCCCAAAAATACCAACACAGGAAATGAAAAACAAACCCTCACAAGGTGATCCTTTTAACAATCGAGTTCAGGACCTTATCAGCTACGT
GGTGAACATGGGTCTGATTGACAAACTGTGTGCCTGCTTCCTCTCGGTGCAAGGCCCAGTGGATGAGAATCCCAAGATGGCCATATTTCT
GCAGCATGCCGCAGGACTCTTACATGCAATGTGTACACTGTGCTTTGCTGTCACTGGAAGGTCATACAGCATATTTGACAATAATCGCCA
GGATCCCACAGGGCTGACAGCTGCTCTTCAGGCAACCGACCTGGCTGGAGTTCTTCATATGCTCTACTGTGTCCTCTTCCATGGCACCAT
CTTGGACCCCAGCACTGCCAGTCCCAAGGAGAATTACACTCAAAATACCATCCAAGTGGCCATTCAGAGTTTACGTTTCTTCAACAGCTT
TGCAGCTCTTCATCTGCCTGCTTTTCAGTCTATTGTAGGGGCAGAGGGCTTGTCCCTTGCATTCCGGCACATGGCCAGCTCCCTGCTGGG
CCACTGCAGCCAAGTCTCCTGTGAAAGCCTCCTTCATGAGGTCATCGTCTGTGTGGGCTACTTCACTGTCAACCACCCAGATAACCAGGT
GATCGTGCAGTCCGGCCGCCACCCCACAGTGCTGCAGAAGCTCTGCCAGTTGCCCTTCCAGTATTTCAGTGACCCACGGCTGATCAAAGT
ACTGTTCCCTTCACTTATCGCTGCTTGTTACAACAACCATCAGAACAAGATCATTCTGGAGCAAGAGATGAGCTGTGTTTTACTGGCCAC
TTTCATTCAGGATTTGGCACAGACTCCAGGTCAAGCGGAAAACCAGCCTTACCAACCCAAAGGGAAATGCCTTGGTTCCCAAGACTATCT
TGAGCTGGCTAACAGATTTCCTCAGCAGGCCTGGGAAGAAGCTCGACAGTTTTTCTTGAAAAAAGAGAAAAAATAAATGTTTTGGTTGAT
TCTGTATTTGAGTACCCTTGTTAATATTTTAAATTGTCCAAACAAACATTCTAATTGTTCCTTAAGAACTCATTTTCCCATGTTTATACT
CTTCCCACACTGTAGATATGGCATGTACTTTACACTATTTATAATGACTGTAGATACTTGAATGTTCTACTTGCTAATTTTGCAAGTTGA
GTTTATTTCATTTATGCAGAGTATCTTGGAGTTTGGTAATTTCCATCTTATGATAATATATACTTTGCATTTGTGATATGGGTGAAAGGA
GACATAAAATTAGCAAGTCTGTTTTGTTCTTGTAATAAAGTAACTTATTCTGTTTTCATTGTTGACTTTTCATGTTAAGGAAATACGAAT

>411_411_3_ABHD17C-SCAPER_ABHD17C_chr15_81042033_ENST00000258884_SCAPER_chr15_76763676_ENST00000563290_length(amino acids)=711AA_BP=295
MQPPSALACQLPRRASVLRPPGPASQPASRAGGGHQAVPMPEPGPRMNGFSLGELCWLFCCPPCPSRIAAKLAFLPPEPTYTVLAPEQRG
AGASAPAPAQATAAAAAAQPAPQQPEEGAGAGPGACSLHLSERADWQYSQRELDAVEVFFSRTARDNRLGCMFVRCAPSSRYTLLFSHGN
AVDLGQMCSFYIGLGSRINCNIFSYDYSGYGVSSGKPSEKNLYADIDAAWQALRTRYGVSPENIILYGQSIGTVPTVDLASRYECAAVIL
HSPLMSGLRVAFPDTRKTYCFDAFPRSLCNAINVYNLTCNNCSENCSDVLFSNKITFLMDLLIHQLTVYVPDENNTILGRNTNKQVFEGL
TTGLLKVSAVVLGCLIANRPDGNCQPATPKIPTQEMKNKPSQGDPFNNRVQDLISYVVNMGLIDKLCACFLSVQGPVDENPKMAIFLQHA
AGLLHAMCTLCFAVTGRSYSIFDNNRQDPTGLTAALQATDLAGVLHMLYCVLFHGTILDPSTASPKENYTQNTIQVAIQSLRFFNSFAAL
HLPAFQSIVGAEGLSLAFRHMASSLLGHCSQVSCESLLHEVIVCVGYFTVNHPDNQVIVQSGRHPTVLQKLCQLPFQYFSDPRLIKVLFP

--------------------------------------------------------------
>411_411_4_ABHD17C-SCAPER_ABHD17C_chr15_81042033_ENST00000560609_SCAPER_chr15_76763676_ENST00000324767_length(transcript)=1952nt_BP=258nt
TTTTACTCAGTCCCTGTTCAAGATGGAGCTGCTCCCATTCAAACACTTCTGACATGTTTACTACTGCCTGGCACAGAGGTATGGCGTGAG
TCCCGAGAACATTATCCTCTATGGTCAGAGCATTGGGACTGTCCCCACGGTAGACTTGGCCTCGAGGTATGAATGCGCAGCGGTAATTCT
CCATTCCCCTCTGATGTCTGGTTTGCGTGTGGCTTTTCCGGATACCAGGAAAACATACTGCTTTGATGCTTTCCCCAGGTCTCTCTGCAA
TGCAATCAATGTTTACAACCTCACCTGCAATAACTGTTCAGAAAACTGCAGTGATGTTCTGTTTAGTAACAAGATTACCTTCTTAATGGA
CCTCCTGATACACCAGTTGACGGTTTATGTTCCAGATGAAAATAATACTATTTTGGGGAGAAATACAAATAAACAAGTTTTTGAAGGCTT
GACAACTGGACTTCTCAAAGTCAGTGCTGTGGTTTTGGGCTGCCTGATTGCCAATCGACCAGATGGAAACTGCCAGCCAGCTACCCCAAA
AATACCAACACAGGAAATGAAAAACAAACCCTCACAAGGTGATCCTTTTAACAATCGAGTTCAGGACCTTATCAGCTACGTGGTGAACAT
GGGTCTGATTGACAAACTGTGTGCCTGCTTCCTCTCGGTGCAAGGCCCAGTGGATGAGAATCCCAAGATGGCCATATTTCTGCAGCATGC
CGCAGGACTCTTACATGCAATGTGTACACTGTGCTTTGCTGTCACTGGAAGGTCATACAGCATATTTGACAATAATCGCCAGGATCCCAC
AGGGCTGACAGCTGCTCTTCAGGCAACCGACCTGGCTGGAGTTCTTCATATGCTCTACTGTGTCCTCTTCCATGGCACCATCTTGGACCC
CAGCACTGCCAGTCCCAAGGAGAATTACACTCAAAATACCATCCAAGTGGCCATTCAGAGTTTACGTTTCTTCAACAGCTTTGCAGCTCT
TCATCTGCCTGCTTTTCAGTCTATTGTAGGGGCAGAGGGCTTGTCCCTTGCATTCCGGCACATGGCCAGCTCCCTGCTGGGCCACTGCAG
CCAAGTCTCCTGTGAAAGCCTCCTTCATGAGGTCATCGTCTGTGTGGGCTACTTCACTGTCAACCACCCAGATAACCAGGTGATCGTGCA
GTCCGGCCGCCACCCCACAGTGCTGCAGAAGCTCTGCCAGTTGCCCTTCCAGTATTTCAGTGACCCACGGCTGATCAAAGTACTGTTCCC
TTCACTTATCGCTGCTTGTTACAACAACCATCAGAACAAGATCATTCTGGAGCAAGAGATGAGCTGTGTTTTACTGGCCACTTTCATTCA
GGATTTGGCACAGACTCCAGGTCAAGCGGAAAACCAGCCTTACCAACCCAAAGGGAAATGCCTTGGTTCCCAAGACTATCTTGAGCTGGC
TAACAGATTTCCTCAGCAGGCCTGGGAAGAAGCTCGACAGTTTTTCTTGAAAAAAGAGAAAAAATAAATGTTTTGGTTGATTCTGTATTT
GAGTACCCTTGTTAATATTTTAAATTGTCCAAACAAACATTCTAATTGTTCCTTAAGAACTCATTTTCCCATGTTTATACTCTTCCCACA
CTGTAGATATGGCATGTACTTTACACTATTTATAATGACTGTAGATACTTGAATGTTCTACTTGCTAATTTTGCAAGTTGAGTTTATTTC
ATTTATGCAGAGTATCTTGGAGTTTGGTAATTTCCATCTTATGATAATATATACTTTGCATTTGTGATATGGGTGAAAGGAGACATAAAA
TTAGCAAGTCTGTTTTGTTCTTGTAATAAAGTAACTTATTCTGTTTTCATTGTTGACTTTTCATGTTAAGGAAATACGAATCTGAAAGAA

>411_411_4_ABHD17C-SCAPER_ABHD17C_chr15_81042033_ENST00000560609_SCAPER_chr15_76763676_ENST00000324767_length(amino acids)=479AA_BP=63
MAQRYGVSPENIILYGQSIGTVPTVDLASRYECAAVILHSPLMSGLRVAFPDTRKTYCFDAFPRSLCNAINVYNLTCNNCSENCSDVLFS
NKITFLMDLLIHQLTVYVPDENNTILGRNTNKQVFEGLTTGLLKVSAVVLGCLIANRPDGNCQPATPKIPTQEMKNKPSQGDPFNNRVQD
LISYVVNMGLIDKLCACFLSVQGPVDENPKMAIFLQHAAGLLHAMCTLCFAVTGRSYSIFDNNRQDPTGLTAALQATDLAGVLHMLYCVL
FHGTILDPSTASPKENYTQNTIQVAIQSLRFFNSFAALHLPAFQSIVGAEGLSLAFRHMASSLLGHCSQVSCESLLHEVIVCVGYFTVNH
PDNQVIVQSGRHPTVLQKLCQLPFQYFSDPRLIKVLFPSLIAACYNNHQNKIILEQEMSCVLLATFIQDLAQTPGQAENQPYQPKGKCLG

--------------------------------------------------------------
>411_411_5_ABHD17C-SCAPER_ABHD17C_chr15_81042033_ENST00000560609_SCAPER_chr15_76763676_ENST00000538941_length(transcript)=1955nt_BP=258nt
TTTTACTCAGTCCCTGTTCAAGATGGAGCTGCTCCCATTCAAACACTTCTGACATGTTTACTACTGCCTGGCACAGAGGTATGGCGTGAG
TCCCGAGAACATTATCCTCTATGGTCAGAGCATTGGGACTGTCCCCACGGTAGACTTGGCCTCGAGGTATGAATGCGCAGCGGTAATTCT
CCATTCCCCTCTGATGTCTGGTTTGCGTGTGGCTTTTCCGGATACCAGGAAAACATACTGCTTTGATGCTTTCCCCAGGTCTCTCTGCAA
TGCAATCAATGTTTACAACCTCACCTGCAATAACTGTTCAGAAAACTGCAGTGATGTTCTGTTTAGTAACAAGATTACCTTCTTAATGGA
CCTCCTGATACACCAGTTGACGGTTTATGTTCCAGATGAAAATAATACTATTTTGGGGAGAAATACAAATAAACAAGTTTTTGAAGGCTT
GACAACTGGACTTCTCAAAGTCAGTGCTGTGGTTTTGGGCTGCCTGATTGCCAATCGACCAGATGGAAACTGCCAGCCAGCTACCCCAAA
AATACCAACACAGGAAATGAAAAACAAACCCTCACAAGGTGATCCTTTTAACAATCGAGTTCAGGACCTTATCAGCTACGTGGTGAACAT
GGGTCTGATTGACAAACTGTGTGCCTGCTTCCTCTCGGTGCAAGGCCCAGTGGATGAGAATCCCAAGATGGCCATATTTCTGCAGCATGC
CGCAGGACTCTTACATGCAATGTGTACACTGTGCTTTGCTGTCACTGGAAGGTCATACAGCATATTTGACAATAATCGCCAGGATCCCAC
AGGGCTGACAGCTGCTCTTCAGGCAACCGACCTGGCTGGAGTTCTTCATATGCTCTACTGTGTCCTCTTCCATGGCACCATCTTGGACCC
CAGCACTGCCAGTCCCAAGGAGAATTACACTCAAAATACCATCCAAGTGGCCATTCAGAGTTTACGTTTCTTCAACAGCTTTGCAGCTCT
TCATCTGCCTGCTTTTCAGTCTATTGTAGGGGCAGAGGGCTTGTCCCTTGCATTCCGGCACATGGCCAGCTCCCTGCTGGGCCACTGCAG
CCAAGTCTCCTGTGAAAGCCTCCTTCATGAGGTCATCGTCTGTGTGGGCTACTTCACTGTCAACCACCCAGATAACCAGGTGATCGTGCA
GTCCGGCCGCCACCCCACAGTGCTGCAGAAGCTCTGCCAGTTGCCCTTCCAGTATTTCAGTGACCCACGGCTGATCAAAGTACTGTTCCC
TTCACTTATCGCTGCTTGTTACAACAACCATCAGAACAAGATCATTCTGGAGCAAGAGATGAGCTGTGTTTTACTGGCCACTTTCATTCA
GGATTTGGCACAGACTCCAGGTCAAGCGGAAAACCAGCCTTACCAACCCAAAGGGAAATGCCTTGGTTCCCAAGACTATCTTGAGCTGGC
TAACAGATTTCCTCAGCAGGCCTGGGAAGAAGCTCGACAGTTTTTCTTGAAAAAAGAGAAAAAATAAATGTTTTGGTTGATTCTGTATTT
GAGTACCCTTGTTAATATTTTAAATTGTCCAAACAAACATTCTAATTGTTCCTTAAGAACTCATTTTCCCATGTTTATACTCTTCCCACA
CTGTAGATATGGCATGTACTTTACACTATTTATAATGACTGTAGATACTTGAATGTTCTACTTGCTAATTTTGCAAGTTGAGTTTATTTC
ATTTATGCAGAGTATCTTGGAGTTTGGTAATTTCCATCTTATGATAATATATACTTTGCATTTGTGATATGGGTGAAAGGAGACATAAAA
TTAGCAAGTCTGTTTTGTTCTTGTAATAAAGTAACTTATTCTGTTTTCATTGTTGACTTTTCATGTTAAGGAAATACGAATCTGAAAGAA

>411_411_5_ABHD17C-SCAPER_ABHD17C_chr15_81042033_ENST00000560609_SCAPER_chr15_76763676_ENST00000538941_length(amino acids)=479AA_BP=63
MAQRYGVSPENIILYGQSIGTVPTVDLASRYECAAVILHSPLMSGLRVAFPDTRKTYCFDAFPRSLCNAINVYNLTCNNCSENCSDVLFS
NKITFLMDLLIHQLTVYVPDENNTILGRNTNKQVFEGLTTGLLKVSAVVLGCLIANRPDGNCQPATPKIPTQEMKNKPSQGDPFNNRVQD
LISYVVNMGLIDKLCACFLSVQGPVDENPKMAIFLQHAAGLLHAMCTLCFAVTGRSYSIFDNNRQDPTGLTAALQATDLAGVLHMLYCVL
FHGTILDPSTASPKENYTQNTIQVAIQSLRFFNSFAALHLPAFQSIVGAEGLSLAFRHMASSLLGHCSQVSCESLLHEVIVCVGYFTVNH
PDNQVIVQSGRHPTVLQKLCQLPFQYFSDPRLIKVLFPSLIAACYNNHQNKIILEQEMSCVLLATFIQDLAQTPGQAENQPYQPKGKCLG

--------------------------------------------------------------
>411_411_6_ABHD17C-SCAPER_ABHD17C_chr15_81042033_ENST00000560609_SCAPER_chr15_76763676_ENST00000563290_length(transcript)=1955nt_BP=258nt
TTTTACTCAGTCCCTGTTCAAGATGGAGCTGCTCCCATTCAAACACTTCTGACATGTTTACTACTGCCTGGCACAGAGGTATGGCGTGAG
TCCCGAGAACATTATCCTCTATGGTCAGAGCATTGGGACTGTCCCCACGGTAGACTTGGCCTCGAGGTATGAATGCGCAGCGGTAATTCT
CCATTCCCCTCTGATGTCTGGTTTGCGTGTGGCTTTTCCGGATACCAGGAAAACATACTGCTTTGATGCTTTCCCCAGGTCTCTCTGCAA
TGCAATCAATGTTTACAACCTCACCTGCAATAACTGTTCAGAAAACTGCAGTGATGTTCTGTTTAGTAACAAGATTACCTTCTTAATGGA
CCTCCTGATACACCAGTTGACGGTTTATGTTCCAGATGAAAATAATACTATTTTGGGGAGAAATACAAATAAACAAGTTTTTGAAGGCTT
GACAACTGGACTTCTCAAAGTCAGTGCTGTGGTTTTGGGCTGCCTGATTGCCAATCGACCAGATGGAAACTGCCAGCCAGCTACCCCAAA
AATACCAACACAGGAAATGAAAAACAAACCCTCACAAGGTGATCCTTTTAACAATCGAGTTCAGGACCTTATCAGCTACGTGGTGAACAT
GGGTCTGATTGACAAACTGTGTGCCTGCTTCCTCTCGGTGCAAGGCCCAGTGGATGAGAATCCCAAGATGGCCATATTTCTGCAGCATGC
CGCAGGACTCTTACATGCAATGTGTACACTGTGCTTTGCTGTCACTGGAAGGTCATACAGCATATTTGACAATAATCGCCAGGATCCCAC
AGGGCTGACAGCTGCTCTTCAGGCAACCGACCTGGCTGGAGTTCTTCATATGCTCTACTGTGTCCTCTTCCATGGCACCATCTTGGACCC
CAGCACTGCCAGTCCCAAGGAGAATTACACTCAAAATACCATCCAAGTGGCCATTCAGAGTTTACGTTTCTTCAACAGCTTTGCAGCTCT
TCATCTGCCTGCTTTTCAGTCTATTGTAGGGGCAGAGGGCTTGTCCCTTGCATTCCGGCACATGGCCAGCTCCCTGCTGGGCCACTGCAG
CCAAGTCTCCTGTGAAAGCCTCCTTCATGAGGTCATCGTCTGTGTGGGCTACTTCACTGTCAACCACCCAGATAACCAGGTGATCGTGCA
GTCCGGCCGCCACCCCACAGTGCTGCAGAAGCTCTGCCAGTTGCCCTTCCAGTATTTCAGTGACCCACGGCTGATCAAAGTACTGTTCCC
TTCACTTATCGCTGCTTGTTACAACAACCATCAGAACAAGATCATTCTGGAGCAAGAGATGAGCTGTGTTTTACTGGCCACTTTCATTCA
GGATTTGGCACAGACTCCAGGTCAAGCGGAAAACCAGCCTTACCAACCCAAAGGGAAATGCCTTGGTTCCCAAGACTATCTTGAGCTGGC
TAACAGATTTCCTCAGCAGGCCTGGGAAGAAGCTCGACAGTTTTTCTTGAAAAAAGAGAAAAAATAAATGTTTTGGTTGATTCTGTATTT
GAGTACCCTTGTTAATATTTTAAATTGTCCAAACAAACATTCTAATTGTTCCTTAAGAACTCATTTTCCCATGTTTATACTCTTCCCACA
CTGTAGATATGGCATGTACTTTACACTATTTATAATGACTGTAGATACTTGAATGTTCTACTTGCTAATTTTGCAAGTTGAGTTTATTTC
ATTTATGCAGAGTATCTTGGAGTTTGGTAATTTCCATCTTATGATAATATATACTTTGCATTTGTGATATGGGTGAAAGGAGACATAAAA
TTAGCAAGTCTGTTTTGTTCTTGTAATAAAGTAACTTATTCTGTTTTCATTGTTGACTTTTCATGTTAAGGAAATACGAATCTGAAAGAA

>411_411_6_ABHD17C-SCAPER_ABHD17C_chr15_81042033_ENST00000560609_SCAPER_chr15_76763676_ENST00000563290_length(amino acids)=479AA_BP=63
MAQRYGVSPENIILYGQSIGTVPTVDLASRYECAAVILHSPLMSGLRVAFPDTRKTYCFDAFPRSLCNAINVYNLTCNNCSENCSDVLFS
NKITFLMDLLIHQLTVYVPDENNTILGRNTNKQVFEGLTTGLLKVSAVVLGCLIANRPDGNCQPATPKIPTQEMKNKPSQGDPFNNRVQD
LISYVVNMGLIDKLCACFLSVQGPVDENPKMAIFLQHAAGLLHAMCTLCFAVTGRSYSIFDNNRQDPTGLTAALQATDLAGVLHMLYCVL
FHGTILDPSTASPKENYTQNTIQVAIQSLRFFNSFAALHLPAFQSIVGAEGLSLAFRHMASSLLGHCSQVSCESLLHEVIVCVGYFTVNH
PDNQVIVQSGRHPTVLQKLCQLPFQYFSDPRLIKVLFPSLIAACYNNHQNKIILEQEMSCVLLATFIQDLAQTPGQAENQPYQPKGKCLG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for FAM108C1-SCAPER


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for FAM108C1-SCAPER


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for FAM108C1-SCAPER


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC4748658INTELLECTUAL DEVELOPMENTAL DISORDER AND RETINITIS PIGMENTOSA2GENOMICS_ENGLAND;UNIPROT
TgeneC0020796Profound Mental Retardation1CTD_human
TgeneC0025363Mental Retardation, Psychosocial1CTD_human
TgeneC0035334Retinitis Pigmentosa1ORPHANET
TgeneC0917816Mental deficiency1CTD_human
TgeneC3714756Intellectual Disability1CTD_human