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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:RPL28-GLB1 (FusionGDB2 ID:HG6158TG2720) |
Fusion Gene Summary for RPL28-GLB1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: RPL28-GLB1 | Fusion gene ID: hg6158tg2720 | Hgene | Tgene | Gene symbol | RPL28 | GLB1 | Gene ID | 6158 | 2720 |
| Gene name | ribosomal protein L28 | galactosidase beta 1 | |
| Synonyms | L28 | EBP|ELNR1|MPS4B | |
| Cytomap | ('RPL28')('GLB1') 19q13.42 | 3p22.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | 60S ribosomal protein L28large ribosomal subunit protein eL28 | beta-galactosidaseacid beta-galactosidaseelastin binding proteinelastin receptor 1, 67kDalactase | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | . | . | |
| Ensembl transtripts involved in fusion gene | ENST00000558131, ENST00000344063, ENST00000458349, ENST00000558815, ENST00000559463, ENST00000560055, ENST00000560583, ENST00000428193, ENST00000431533, ENST00000558752, | ||
| Fusion gene scores | * DoF score | 22 X 17 X 5=1870 | 9 X 9 X 5=405 |
| # samples | 24 | 9 | |
| ** MAII score | log2(24/1870*10)=-2.96193195916648 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(9/405*10)=-2.16992500144231 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: RPL28 [Title/Abstract] AND GLB1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | RPL28(55899416)-GLB1(33114206), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | GLB1 | GO:0044262 | cellular carbohydrate metabolic process | 11927518 |
| Fusion gene breakpoints across RPL28 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across GLB1 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
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Fusion Gene ORF analysis for RPL28-GLB1 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000344063 | ENST00000307363 | RPL28 | chr19 | 55899416 | + | GLB1 | chr3 | 33114206 | - | 0.001265971 | 0.99873406 |
| ENST00000558815 | ENST00000307363 | RPL28 | chr19 | 55899416 | + | GLB1 | chr3 | 33114206 | - | 0.001049121 | 0.99895084 |
| ENST00000560583 | ENST00000307363 | RPL28 | chr19 | 55899416 | + | GLB1 | chr3 | 33114206 | - | 0.001758995 | 0.99824095 |
| ENST00000560055 | ENST00000307363 | RPL28 | chr19 | 55899416 | + | GLB1 | chr3 | 33114206 | - | 0.001050032 | 0.99894994 |
| ENST00000559463 | ENST00000307363 | RPL28 | chr19 | 55899416 | + | GLB1 | chr3 | 33114206 | - | 0.000988573 | 0.9990114 |
| ENST00000458349 | ENST00000307363 | RPL28 | chr19 | 55899416 | + | GLB1 | chr3 | 33114206 | - | 0.001010643 | 0.9989894 |
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Fusion Genomic Features for RPL28-GLB1 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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Fusion Protein Features for RPL28-GLB1 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:55899416/chr3:33114206) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | . |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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Fusion Gene Sequence for RPL28-GLB1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >76372_76372_1_RPL28-GLB1_RPL28_chr19_55899416_ENST00000344063_GLB1_chr3_33114206_ENST00000307363_length(transcript)=3349nt_BP=953nt GGGAGGGCGAACTGCAAGAGGGCTGCCAGGATTAGCCGAGGGATTCCGAATGAAGACGGAGTATTTCCGAACATACACACCTCTCCCAAG AGCGTTTCCGGAGGGTTCCGAAAATACCCGAGCGGGCCTCGGCGCCCTCATTGGCCATCACCGCGAGGGCTTACGAAGACCGGAAATATC CAAAGGTGCCGGGGCTAGGCTTATATAGTTCACGCATTCACCAGTTCATTCATAAAACAAATGTTTGTTGAGCGCCCATCATATGCCAAT CACAGTGACAAGTGCTGGGTGAGCAATACTGGAGAGATAACGCTGAGGTATGGGTCCCAGGACCTCTCGAATTGGAGCCACTCGGAAATC CAGCGGTAGAGTTTCGAAAACTTCCGAACGGTTCCCGGAATACGCTCTCGGCCCTCTAACCGAAGAGTTCCGAATATTCCCGAGCGTTGA GCGAATTTTCGGCGGAAGCAGCCGAACATCATCGAGCCGCCTCGGAGGTGGGGACCGACAACTCCTGTCGTGCCCGCCCGGAGAGGAAGC GGAAATGCGTGTACGGTATTAAAGGCGTCGCCTCGCCCCTCGCCTTCCTCTTTCCGTCTCAGGTCGCCGCTGCGAAGGGAGCCGCCGCCA TGTCTGCGCATCTGCAATGGATGGTCGTGCGGAACTGCTCCAGTTTCCTGATCAAGAGGAATAAGCAGACCTACAGCACTGAGCCCAATA ACTTGAAGGCCCGCAATTCCTTCCGCTACAACGGACTGATTCACCGCAAGACTGTGGGCGTGGAGCCGGCAGCCGACGGCAAAGGTGTCG TGGTGGTCATTAAGCGGAGATCCGGCCAGCGGAAGCCTGCCACCTCCTATGTGCGGACCACCATCAACAAGAATGCTCGCGCCACGCTCA GCAGCATCAGACACATGATCCGCAAGAACAAGTACCGCCCCGACCTGCGCATGAATGCCACCCAGAGGATGTTTGAAATTGACTATAGCC GGGACTCCTTCCTCAAGGATGGCCAGCCATTTCGCTACATCTCAGGAAGCATTCACTACTCCCGTGTGCCCCGCTTCTACTGGAAGGACC GGCTGCTGAAGATGAAGATGGCTGGGCTGAACGCCATCCAGACGTATGTGCCCTGGAACTTTCATGAGCCCTGGCCAGGACAGTACCAGT TTTCTGAGGACCATGATGTGGAATATTTTCTTCGGCTGGCTCATGAGCTGGGACTGCTGGTTATCCTGAGGCCCGGGCCCTACATCTGTG CAGAGTGGGAAATGGGAGGATTACCTGCTTGGCTGCTAGAGAAAGAGTCTATTCTTCTCCGCTCCTCCGACCCAGATTACCTGGCAGCTG TGGACAAGTGGTTGGGAGTCCTTCTGCCCAAGATGAAGCCTCTCCTCTATCAGAATGGAGGGCCAGTTATAACAGTGCAGGTTGAAAATG AATATGGCAGCTACTTTGCCTGTGATTTTGACTACCTGCGCTTCCTGCAGAAGCGCTTTCGCCACCATCTGGGGGATGATGTGGTTCTGT TTACCACTGATGGAGCACATAAAACATTCCTGAAATGTGGGGCCCTGCAGGGCCTCTACACCACGGTGGACTTTGGAACAGGCAGCAACA TCACAGATGCTTTCCTAAGCCAGAGGAAGTGTGAGCCCAAAGGACCCTTGATCAATTCTGAATTCTATACTGGCTGGCTAGATCACTGGG GCCAACCTCACTCCACAATCAAGACCGAAGCAGTGGCTTCCTCCCTCTATGATATACTTGCCCGTGGGGCGAGTGTGAACTTGTACATGT TTATAGGTGGGACCAATTTTGCCTATTGGAATGGGGCCAACTCACCCTATGCAGCACAGCCCACCAGCTACGACTATGATGCCCCACTGA GTGAGGCTGGGGACCTCACTGAGAAGTATTTTGCTCTGCGAAACATCATCCAGAAGTTTGAAAAAGTACCAGAAGGTCCTATCCCTCCAT CTACACCAAAGTTTGCATATGGAAAGGTCACTTTGGAAAAGTTAAAGACAGTGGGAGCAGCTCTGGACATTCTGTGTCCCTCTGGGCCCA TCAAAAGCCTTTATCCCTTGACATTTATCCAGGTGAAACAGCATTATGGGTTTGTGCTGTACCGGACAACACTTCCTCAAGATTGCAGCA ACCCAGCACCTCTCTCTTCACCCCTCAATGGAGTCCACGATCGAGCATATGTTGCTGTGGATGGGATCCCCCAGGGAGTCCTTGAGCGAA ACAATGTGATCACTCTGAACATAACAGGGAAAGCTGGAGCCACTCTGGACCTTCTGGTAGAGAACATGGGACGTGTGAACTATGGTGCAT ATATCAACGATTTTAAGGGTTTGGTTTCTAACCTGACTCTCAGTTCCAATATCCTCACGGACTGGACGATCTTTCCACTGGACACTGAGG ATGCAGTGTGCAGCCACCTGGGGGGCTGGGGACACCGTGACAGTGGCCACCATGATGAAGCCTGGGCCCACAACTCATCCAACTACACGC TCCCGGCCTTTTATATGGGGAACTTCTCCATTCCCAGTGGGATCCCAGACTTGCCCCAGGACACCTTTATCCAGTTTCCTGGATGGACCA AGGGCCAGGTCTGGATTAATGGCTTTAACCTTGGCCGCTATTGGCCAGCCCGGGGCCCTCAGTTGACCTTGTTTGTGCCCCAGCACATCC TGATGACCTCGGCCCCAAACACCATCACCGTGCTGGAACTGGAGTGGGCACCCTGCAGCAGTGATGATCCAGAACTATGTGCTGTGACGT TCGTGGACAGGCCAGTTATTGGCTCATCTGTGACCTACGATCATCCCTCCAAACCTGTTGAAAAAAGACTCATGCCCCCACCCCCGCAAA AAAACAAAGATTCATGGCTGGACCATGTATGATGATGAAAGCCTGTGTCTTTGAGGGATTCTACCCTGAACATACCTCACAGATCCTCCC TGTCATGCCACATTTCACTGATTGGAATGTGGAAATGGAAAAGGAATTTAGGATGTGCATTTTCACCTGAGGTTTCCCTGCATCCCTGCA GTGCCAAAGCCCCACCTTCAGGGACCACCTGGAATGTGTGAGGGGCTGACAGCACAGTAACGTGCATACATATCTGCAGGGCTGGAATGG AAGCTTTAAAGGTGGTAGTGATTTTTATTTTGGAAGAATCATGTTACCTTTTTGTTAAATAAAATTTGTACTCAAATGATGATGTCACTG TTTTTAATGTGCAGGTATTGAATTATATGGTCTGACTTAAATCATAACTAGACTTGAGTGGGCTGAATAAACCACTTCACTAACTTGAAG >76372_76372_1_RPL28-GLB1_RPL28_chr19_55899416_ENST00000344063_GLB1_chr3_33114206_ENST00000307363_length(amino acids)=821AA_BP=169 MSEFSAEAAEHHRAASEVGTDNSCRARPERKRKCVYGIKGVASPLAFLFPSQVAAAKGAAAMSAHLQWMVVRNCSSFLIKRNKQTYSTEP NNLKARNSFRYNGLIHRKTVGVEPAADGKGVVVVIKRRSGQRKPATSYVRTTINKNARATLSSIRHMIRKNKYRPDLRMNATQRMFEIDY SRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVILRPGPYI CAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFLQKRFRHHLGDDVV LFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGPLINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARGASVNLY MFIGGTNFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEGPIPPSTPKFAYGKVTLEKLKTVGAALDILCPSG PIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDRAYVAVDGIPQGVLERNNVITLNITGKAGATLDLLVENMGRVNYG AYINDFKGLVSNLTLSSNILTDWTIFPLDTEDAVCSHLGGWGHRDSGHHDEAWAHNSSNYTLPAFYMGNFSIPSGIPDLPQDTFIQFPGW TKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPNTITVLELEWAPCSSDDPELCAVTFVDRPVIGSSVTYDHPSKPVEKRLMPPPP -------------------------------------------------------------- >76372_76372_2_RPL28-GLB1_RPL28_chr19_55899416_ENST00000458349_GLB1_chr3_33114206_ENST00000307363_length(transcript)=2720nt_BP=324nt ATGTCTGCGCATCTGCAATGGATGGTCGTGCGGAACTGCTCCAGTTTCCTGATCAAGAGGAATAAGCAGACCTACAGCACTGAGCCCAAT AACTTGAAGGCCCGCAATTCCTTCCGCTACAACGGACTGATTCACCGCAAGACTGTGGGCGTGGAGCCGGCAGCCGACGGCAAAGGTGTC GTGGTGGTCATTAAGCGGAGATCCGGCCAGCGGAAGCCTGCCACCTCCTATGTGCGGACCACCATCAACAAGAATGCTCGCGCCACGCTC AGCAGCATCAGACACATGATCCGCAAGAACAAGTACCGCCCCGACCTGCGCATGAATGCCACCCAGAGGATGTTTGAAATTGACTATAGC CGGGACTCCTTCCTCAAGGATGGCCAGCCATTTCGCTACATCTCAGGAAGCATTCACTACTCCCGTGTGCCCCGCTTCTACTGGAAGGAC CGGCTGCTGAAGATGAAGATGGCTGGGCTGAACGCCATCCAGACGTATGTGCCCTGGAACTTTCATGAGCCCTGGCCAGGACAGTACCAG TTTTCTGAGGACCATGATGTGGAATATTTTCTTCGGCTGGCTCATGAGCTGGGACTGCTGGTTATCCTGAGGCCCGGGCCCTACATCTGT GCAGAGTGGGAAATGGGAGGATTACCTGCTTGGCTGCTAGAGAAAGAGTCTATTCTTCTCCGCTCCTCCGACCCAGATTACCTGGCAGCT GTGGACAAGTGGTTGGGAGTCCTTCTGCCCAAGATGAAGCCTCTCCTCTATCAGAATGGAGGGCCAGTTATAACAGTGCAGGTTGAAAAT GAATATGGCAGCTACTTTGCCTGTGATTTTGACTACCTGCGCTTCCTGCAGAAGCGCTTTCGCCACCATCTGGGGGATGATGTGGTTCTG TTTACCACTGATGGAGCACATAAAACATTCCTGAAATGTGGGGCCCTGCAGGGCCTCTACACCACGGTGGACTTTGGAACAGGCAGCAAC ATCACAGATGCTTTCCTAAGCCAGAGGAAGTGTGAGCCCAAAGGACCCTTGATCAATTCTGAATTCTATACTGGCTGGCTAGATCACTGG GGCCAACCTCACTCCACAATCAAGACCGAAGCAGTGGCTTCCTCCCTCTATGATATACTTGCCCGTGGGGCGAGTGTGAACTTGTACATG TTTATAGGTGGGACCAATTTTGCCTATTGGAATGGGGCCAACTCACCCTATGCAGCACAGCCCACCAGCTACGACTATGATGCCCCACTG AGTGAGGCTGGGGACCTCACTGAGAAGTATTTTGCTCTGCGAAACATCATCCAGAAGTTTGAAAAAGTACCAGAAGGTCCTATCCCTCCA TCTACACCAAAGTTTGCATATGGAAAGGTCACTTTGGAAAAGTTAAAGACAGTGGGAGCAGCTCTGGACATTCTGTGTCCCTCTGGGCCC ATCAAAAGCCTTTATCCCTTGACATTTATCCAGGTGAAACAGCATTATGGGTTTGTGCTGTACCGGACAACACTTCCTCAAGATTGCAGC AACCCAGCACCTCTCTCTTCACCCCTCAATGGAGTCCACGATCGAGCATATGTTGCTGTGGATGGGATCCCCCAGGGAGTCCTTGAGCGA AACAATGTGATCACTCTGAACATAACAGGGAAAGCTGGAGCCACTCTGGACCTTCTGGTAGAGAACATGGGACGTGTGAACTATGGTGCA TATATCAACGATTTTAAGGGTTTGGTTTCTAACCTGACTCTCAGTTCCAATATCCTCACGGACTGGACGATCTTTCCACTGGACACTGAG GATGCAGTGTGCAGCCACCTGGGGGGCTGGGGACACCGTGACAGTGGCCACCATGATGAAGCCTGGGCCCACAACTCATCCAACTACACG CTCCCGGCCTTTTATATGGGGAACTTCTCCATTCCCAGTGGGATCCCAGACTTGCCCCAGGACACCTTTATCCAGTTTCCTGGATGGACC AAGGGCCAGGTCTGGATTAATGGCTTTAACCTTGGCCGCTATTGGCCAGCCCGGGGCCCTCAGTTGACCTTGTTTGTGCCCCAGCACATC CTGATGACCTCGGCCCCAAACACCATCACCGTGCTGGAACTGGAGTGGGCACCCTGCAGCAGTGATGATCCAGAACTATGTGCTGTGACG TTCGTGGACAGGCCAGTTATTGGCTCATCTGTGACCTACGATCATCCCTCCAAACCTGTTGAAAAAAGACTCATGCCCCCACCCCCGCAA AAAAACAAAGATTCATGGCTGGACCATGTATGATGATGAAAGCCTGTGTCTTTGAGGGATTCTACCCTGAACATACCTCACAGATCCTCC CTGTCATGCCACATTTCACTGATTGGAATGTGGAAATGGAAAAGGAATTTAGGATGTGCATTTTCACCTGAGGTTTCCCTGCATCCCTGC AGTGCCAAAGCCCCACCTTCAGGGACCACCTGGAATGTGTGAGGGGCTGACAGCACAGTAACGTGCATACATATCTGCAGGGCTGGAATG GAAGCTTTAAAGGTGGTAGTGATTTTTATTTTGGAAGAATCATGTTACCTTTTTGTTAAATAAAATTTGTACTCAAATGATGATGTCACT GTTTTTAATGTGCAGGTATTGAATTATATGGTCTGACTTAAATCATAACTAGACTTGAGTGGGCTGAATAAACCACTTCACTAACTTGAA >76372_76372_2_RPL28-GLB1_RPL28_chr19_55899416_ENST00000458349_GLB1_chr3_33114206_ENST00000307363_length(amino acids)=760AA_BP=108 MSAHLQWMVVRNCSSFLIKRNKQTYSTEPNNLKARNSFRYNGLIHRKTVGVEPAADGKGVVVVIKRRSGQRKPATSYVRTTINKNARATL SSIRHMIRKNKYRPDLRMNATQRMFEIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQ FSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVEN EYGSYFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGPLINSEFYTGWLDHW GQPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEGPIPP STPKFAYGKVTLEKLKTVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDRAYVAVDGIPQGVLER NNVITLNITGKAGATLDLLVENMGRVNYGAYINDFKGLVSNLTLSSNILTDWTIFPLDTEDAVCSHLGGWGHRDSGHHDEAWAHNSSNYT LPAFYMGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPNTITVLELEWAPCSSDDPELCAVT -------------------------------------------------------------- >76372_76372_3_RPL28-GLB1_RPL28_chr19_55899416_ENST00000558815_GLB1_chr3_33114206_ENST00000307363_length(transcript)=2762nt_BP=366nt CTCTTTCCGTCTCAGGTCGCCGCTGCGAAGGGAGCCGCCGCCATGTCTGCGCATCTGCAATGGATGGTCGTGCGGAACTGCTCCAGTTTC CTGATCAAGAGGAATAAGCAGACCTACAGCACTGAGCCCAATAACTTGAAGGCCCGCAATTCCTTCCGCTACAACGGACTGATTCACCGC AAGACTGTGGGCGTGGAGCCGGCAGCCGACGGCAAAGGTGTCGTGGTGGTCATTAAGCGGAGATCCGGCCAGCGGAAGCCTGCCACCTCC TATGTGCGGACCACCATCAACAAGAATGCTCGCGCCACGCTCAGCAGCATCAGACACATGATCCGCAAGAACAAGTACCGCCCCGACCTG CGCATGAATGCCACCCAGAGGATGTTTGAAATTGACTATAGCCGGGACTCCTTCCTCAAGGATGGCCAGCCATTTCGCTACATCTCAGGA AGCATTCACTACTCCCGTGTGCCCCGCTTCTACTGGAAGGACCGGCTGCTGAAGATGAAGATGGCTGGGCTGAACGCCATCCAGACGTAT GTGCCCTGGAACTTTCATGAGCCCTGGCCAGGACAGTACCAGTTTTCTGAGGACCATGATGTGGAATATTTTCTTCGGCTGGCTCATGAG CTGGGACTGCTGGTTATCCTGAGGCCCGGGCCCTACATCTGTGCAGAGTGGGAAATGGGAGGATTACCTGCTTGGCTGCTAGAGAAAGAG TCTATTCTTCTCCGCTCCTCCGACCCAGATTACCTGGCAGCTGTGGACAAGTGGTTGGGAGTCCTTCTGCCCAAGATGAAGCCTCTCCTC TATCAGAATGGAGGGCCAGTTATAACAGTGCAGGTTGAAAATGAATATGGCAGCTACTTTGCCTGTGATTTTGACTACCTGCGCTTCCTG CAGAAGCGCTTTCGCCACCATCTGGGGGATGATGTGGTTCTGTTTACCACTGATGGAGCACATAAAACATTCCTGAAATGTGGGGCCCTG CAGGGCCTCTACACCACGGTGGACTTTGGAACAGGCAGCAACATCACAGATGCTTTCCTAAGCCAGAGGAAGTGTGAGCCCAAAGGACCC TTGATCAATTCTGAATTCTATACTGGCTGGCTAGATCACTGGGGCCAACCTCACTCCACAATCAAGACCGAAGCAGTGGCTTCCTCCCTC TATGATATACTTGCCCGTGGGGCGAGTGTGAACTTGTACATGTTTATAGGTGGGACCAATTTTGCCTATTGGAATGGGGCCAACTCACCC TATGCAGCACAGCCCACCAGCTACGACTATGATGCCCCACTGAGTGAGGCTGGGGACCTCACTGAGAAGTATTTTGCTCTGCGAAACATC ATCCAGAAGTTTGAAAAAGTACCAGAAGGTCCTATCCCTCCATCTACACCAAAGTTTGCATATGGAAAGGTCACTTTGGAAAAGTTAAAG ACAGTGGGAGCAGCTCTGGACATTCTGTGTCCCTCTGGGCCCATCAAAAGCCTTTATCCCTTGACATTTATCCAGGTGAAACAGCATTAT GGGTTTGTGCTGTACCGGACAACACTTCCTCAAGATTGCAGCAACCCAGCACCTCTCTCTTCACCCCTCAATGGAGTCCACGATCGAGCA TATGTTGCTGTGGATGGGATCCCCCAGGGAGTCCTTGAGCGAAACAATGTGATCACTCTGAACATAACAGGGAAAGCTGGAGCCACTCTG GACCTTCTGGTAGAGAACATGGGACGTGTGAACTATGGTGCATATATCAACGATTTTAAGGGTTTGGTTTCTAACCTGACTCTCAGTTCC AATATCCTCACGGACTGGACGATCTTTCCACTGGACACTGAGGATGCAGTGTGCAGCCACCTGGGGGGCTGGGGACACCGTGACAGTGGC CACCATGATGAAGCCTGGGCCCACAACTCATCCAACTACACGCTCCCGGCCTTTTATATGGGGAACTTCTCCATTCCCAGTGGGATCCCA GACTTGCCCCAGGACACCTTTATCCAGTTTCCTGGATGGACCAAGGGCCAGGTCTGGATTAATGGCTTTAACCTTGGCCGCTATTGGCCA GCCCGGGGCCCTCAGTTGACCTTGTTTGTGCCCCAGCACATCCTGATGACCTCGGCCCCAAACACCATCACCGTGCTGGAACTGGAGTGG GCACCCTGCAGCAGTGATGATCCAGAACTATGTGCTGTGACGTTCGTGGACAGGCCAGTTATTGGCTCATCTGTGACCTACGATCATCCC TCCAAACCTGTTGAAAAAAGACTCATGCCCCCACCCCCGCAAAAAAACAAAGATTCATGGCTGGACCATGTATGATGATGAAAGCCTGTG TCTTTGAGGGATTCTACCCTGAACATACCTCACAGATCCTCCCTGTCATGCCACATTTCACTGATTGGAATGTGGAAATGGAAAAGGAAT TTAGGATGTGCATTTTCACCTGAGGTTTCCCTGCATCCCTGCAGTGCCAAAGCCCCACCTTCAGGGACCACCTGGAATGTGTGAGGGGCT GACAGCACAGTAACGTGCATACATATCTGCAGGGCTGGAATGGAAGCTTTAAAGGTGGTAGTGATTTTTATTTTGGAAGAATCATGTTAC CTTTTTGTTAAATAAAATTTGTACTCAAATGATGATGTCACTGTTTTTAATGTGCAGGTATTGAATTATATGGTCTGACTTAAATCATAA >76372_76372_3_RPL28-GLB1_RPL28_chr19_55899416_ENST00000558815_GLB1_chr3_33114206_ENST00000307363_length(amino acids)=760AA_BP=108 MSAHLQWMVVRNCSSFLIKRNKQTYSTEPNNLKARNSFRYNGLIHRKTVGVEPAADGKGVVVVIKRRSGQRKPATSYVRTTINKNARATL SSIRHMIRKNKYRPDLRMNATQRMFEIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQ FSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVEN EYGSYFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGPLINSEFYTGWLDHW GQPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEGPIPP STPKFAYGKVTLEKLKTVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDRAYVAVDGIPQGVLER NNVITLNITGKAGATLDLLVENMGRVNYGAYINDFKGLVSNLTLSSNILTDWTIFPLDTEDAVCSHLGGWGHRDSGHHDEAWAHNSSNYT LPAFYMGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPNTITVLELEWAPCSSDDPELCAVT -------------------------------------------------------------- >76372_76372_4_RPL28-GLB1_RPL28_chr19_55899416_ENST00000559463_GLB1_chr3_33114206_ENST00000307363_length(transcript)=3117nt_BP=721nt GGGAGGTGAGCGTTCGTCTTCCTCGCGTGGTCGCCATCTCCGGCCCGCCGCGCACTCCCTCTCAGTCCTCTGCCTGCCTTCTCCCCTTGC GCCTCAAGGGTCATTGGCGGACCCCAACCCCTCCCCGTGAAGTCGTTGTGAATTTTCAAGTTATTTTCCCCTCACTCTCATTCGCCGCAG CTAGTCTCGGCTGCCTGAATTCGGTCCCGCCGCCTTAGGTCACTCAGTCCCGCCTGACAAGAGTTCTAGGTCGCTGTCTGCCCTCAGGGG TCTCCCATTCACCCAAGTTCCCAGTCGCTCTCTTCCTCTGCTGTCCGAGCGTGGCCCGTGGCCTAACGCTGCTTTAGTTCTCTGTGTCTG ACGCTTTCCCTGTGCCCGTTTCCCCGCAGCCGCCGCCATGTCTGCGCATCTGCAATGGATGGTCGTGCGGAACTGCTCCAGTTTCCTGAT CAAGAGGAATAAGCAGACCTACAGCACTGAGCCCAATAACTTGAAGGCCCGCAATTCCTTCCGCTACAACGGACTGATTCACCGCAAGAC TGTGGGCGTGGAGCCGGCAGCCGACGGCAAAGGTGTCGTGGTGGTCATTAAGCGGAGATCCGGCCAGCGGAAGCCTGCCACCTCCTATGT GCGGACCACCATCAACAAGAATGCTCGCGCCACGCTCAGCAGCATCAGACACATGATCCGCAAGAACAAGTACCGCCCCGACCTGCGCAT GAATGCCACCCAGAGGATGTTTGAAATTGACTATAGCCGGGACTCCTTCCTCAAGGATGGCCAGCCATTTCGCTACATCTCAGGAAGCAT TCACTACTCCCGTGTGCCCCGCTTCTACTGGAAGGACCGGCTGCTGAAGATGAAGATGGCTGGGCTGAACGCCATCCAGACGTATGTGCC CTGGAACTTTCATGAGCCCTGGCCAGGACAGTACCAGTTTTCTGAGGACCATGATGTGGAATATTTTCTTCGGCTGGCTCATGAGCTGGG ACTGCTGGTTATCCTGAGGCCCGGGCCCTACATCTGTGCAGAGTGGGAAATGGGAGGATTACCTGCTTGGCTGCTAGAGAAAGAGTCTAT TCTTCTCCGCTCCTCCGACCCAGATTACCTGGCAGCTGTGGACAAGTGGTTGGGAGTCCTTCTGCCCAAGATGAAGCCTCTCCTCTATCA GAATGGAGGGCCAGTTATAACAGTGCAGGTTGAAAATGAATATGGCAGCTACTTTGCCTGTGATTTTGACTACCTGCGCTTCCTGCAGAA GCGCTTTCGCCACCATCTGGGGGATGATGTGGTTCTGTTTACCACTGATGGAGCACATAAAACATTCCTGAAATGTGGGGCCCTGCAGGG CCTCTACACCACGGTGGACTTTGGAACAGGCAGCAACATCACAGATGCTTTCCTAAGCCAGAGGAAGTGTGAGCCCAAAGGACCCTTGAT CAATTCTGAATTCTATACTGGCTGGCTAGATCACTGGGGCCAACCTCACTCCACAATCAAGACCGAAGCAGTGGCTTCCTCCCTCTATGA TATACTTGCCCGTGGGGCGAGTGTGAACTTGTACATGTTTATAGGTGGGACCAATTTTGCCTATTGGAATGGGGCCAACTCACCCTATGC AGCACAGCCCACCAGCTACGACTATGATGCCCCACTGAGTGAGGCTGGGGACCTCACTGAGAAGTATTTTGCTCTGCGAAACATCATCCA GAAGTTTGAAAAAGTACCAGAAGGTCCTATCCCTCCATCTACACCAAAGTTTGCATATGGAAAGGTCACTTTGGAAAAGTTAAAGACAGT GGGAGCAGCTCTGGACATTCTGTGTCCCTCTGGGCCCATCAAAAGCCTTTATCCCTTGACATTTATCCAGGTGAAACAGCATTATGGGTT TGTGCTGTACCGGACAACACTTCCTCAAGATTGCAGCAACCCAGCACCTCTCTCTTCACCCCTCAATGGAGTCCACGATCGAGCATATGT TGCTGTGGATGGGATCCCCCAGGGAGTCCTTGAGCGAAACAATGTGATCACTCTGAACATAACAGGGAAAGCTGGAGCCACTCTGGACCT TCTGGTAGAGAACATGGGACGTGTGAACTATGGTGCATATATCAACGATTTTAAGGGTTTGGTTTCTAACCTGACTCTCAGTTCCAATAT CCTCACGGACTGGACGATCTTTCCACTGGACACTGAGGATGCAGTGTGCAGCCACCTGGGGGGCTGGGGACACCGTGACAGTGGCCACCA TGATGAAGCCTGGGCCCACAACTCATCCAACTACACGCTCCCGGCCTTTTATATGGGGAACTTCTCCATTCCCAGTGGGATCCCAGACTT GCCCCAGGACACCTTTATCCAGTTTCCTGGATGGACCAAGGGCCAGGTCTGGATTAATGGCTTTAACCTTGGCCGCTATTGGCCAGCCCG GGGCCCTCAGTTGACCTTGTTTGTGCCCCAGCACATCCTGATGACCTCGGCCCCAAACACCATCACCGTGCTGGAACTGGAGTGGGCACC CTGCAGCAGTGATGATCCAGAACTATGTGCTGTGACGTTCGTGGACAGGCCAGTTATTGGCTCATCTGTGACCTACGATCATCCCTCCAA ACCTGTTGAAAAAAGACTCATGCCCCCACCCCCGCAAAAAAACAAAGATTCATGGCTGGACCATGTATGATGATGAAAGCCTGTGTCTTT GAGGGATTCTACCCTGAACATACCTCACAGATCCTCCCTGTCATGCCACATTTCACTGATTGGAATGTGGAAATGGAAAAGGAATTTAGG ATGTGCATTTTCACCTGAGGTTTCCCTGCATCCCTGCAGTGCCAAAGCCCCACCTTCAGGGACCACCTGGAATGTGTGAGGGGCTGACAG CACAGTAACGTGCATACATATCTGCAGGGCTGGAATGGAAGCTTTAAAGGTGGTAGTGATTTTTATTTTGGAAGAATCATGTTACCTTTT TGTTAAATAAAATTTGTACTCAAATGATGATGTCACTGTTTTTAATGTGCAGGTATTGAATTATATGGTCTGACTTAAATCATAACTAGA >76372_76372_4_RPL28-GLB1_RPL28_chr19_55899416_ENST00000559463_GLB1_chr3_33114206_ENST00000307363_length(amino acids)=760AA_BP=108 MSAHLQWMVVRNCSSFLIKRNKQTYSTEPNNLKARNSFRYNGLIHRKTVGVEPAADGKGVVVVIKRRSGQRKPATSYVRTTINKNARATL SSIRHMIRKNKYRPDLRMNATQRMFEIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQ FSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVEN EYGSYFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGPLINSEFYTGWLDHW GQPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEGPIPP STPKFAYGKVTLEKLKTVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDRAYVAVDGIPQGVLER NNVITLNITGKAGATLDLLVENMGRVNYGAYINDFKGLVSNLTLSSNILTDWTIFPLDTEDAVCSHLGGWGHRDSGHHDEAWAHNSSNYT LPAFYMGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPNTITVLELEWAPCSSDDPELCAVT -------------------------------------------------------------- >76372_76372_5_RPL28-GLB1_RPL28_chr19_55899416_ENST00000560055_GLB1_chr3_33114206_ENST00000307363_length(transcript)=2758nt_BP=362nt TTCCGTCTCAGGTCGCCGCTGCGAAGGGAGCCGCCGCCATGTCTGCGCATCTGCAATGGATGGTCGTGCGGAACTGCTCCAGTTTCCTGA TCAAGAGGAATAAGCAGACCTACAGCACTGAGCCCAATAACTTGAAGGCCCGCAATTCCTTCCGCTACAACGGACTGATTCACCGCAAGA CTGTGGGCGTGGAGCCGGCAGCCGACGGCAAAGGTGTCGTGGTGGTCATTAAGCGGAGATCCGGCCAGCGGAAGCCTGCCACCTCCTATG TGCGGACCACCATCAACAAGAATGCTCGCGCCACGCTCAGCAGCATCAGACACATGATCCGCAAGAACAAGTACCGCCCCGACCTGCGCA TGAATGCCACCCAGAGGATGTTTGAAATTGACTATAGCCGGGACTCCTTCCTCAAGGATGGCCAGCCATTTCGCTACATCTCAGGAAGCA TTCACTACTCCCGTGTGCCCCGCTTCTACTGGAAGGACCGGCTGCTGAAGATGAAGATGGCTGGGCTGAACGCCATCCAGACGTATGTGC CCTGGAACTTTCATGAGCCCTGGCCAGGACAGTACCAGTTTTCTGAGGACCATGATGTGGAATATTTTCTTCGGCTGGCTCATGAGCTGG GACTGCTGGTTATCCTGAGGCCCGGGCCCTACATCTGTGCAGAGTGGGAAATGGGAGGATTACCTGCTTGGCTGCTAGAGAAAGAGTCTA TTCTTCTCCGCTCCTCCGACCCAGATTACCTGGCAGCTGTGGACAAGTGGTTGGGAGTCCTTCTGCCCAAGATGAAGCCTCTCCTCTATC AGAATGGAGGGCCAGTTATAACAGTGCAGGTTGAAAATGAATATGGCAGCTACTTTGCCTGTGATTTTGACTACCTGCGCTTCCTGCAGA AGCGCTTTCGCCACCATCTGGGGGATGATGTGGTTCTGTTTACCACTGATGGAGCACATAAAACATTCCTGAAATGTGGGGCCCTGCAGG GCCTCTACACCACGGTGGACTTTGGAACAGGCAGCAACATCACAGATGCTTTCCTAAGCCAGAGGAAGTGTGAGCCCAAAGGACCCTTGA TCAATTCTGAATTCTATACTGGCTGGCTAGATCACTGGGGCCAACCTCACTCCACAATCAAGACCGAAGCAGTGGCTTCCTCCCTCTATG ATATACTTGCCCGTGGGGCGAGTGTGAACTTGTACATGTTTATAGGTGGGACCAATTTTGCCTATTGGAATGGGGCCAACTCACCCTATG CAGCACAGCCCACCAGCTACGACTATGATGCCCCACTGAGTGAGGCTGGGGACCTCACTGAGAAGTATTTTGCTCTGCGAAACATCATCC AGAAGTTTGAAAAAGTACCAGAAGGTCCTATCCCTCCATCTACACCAAAGTTTGCATATGGAAAGGTCACTTTGGAAAAGTTAAAGACAG TGGGAGCAGCTCTGGACATTCTGTGTCCCTCTGGGCCCATCAAAAGCCTTTATCCCTTGACATTTATCCAGGTGAAACAGCATTATGGGT TTGTGCTGTACCGGACAACACTTCCTCAAGATTGCAGCAACCCAGCACCTCTCTCTTCACCCCTCAATGGAGTCCACGATCGAGCATATG TTGCTGTGGATGGGATCCCCCAGGGAGTCCTTGAGCGAAACAATGTGATCACTCTGAACATAACAGGGAAAGCTGGAGCCACTCTGGACC TTCTGGTAGAGAACATGGGACGTGTGAACTATGGTGCATATATCAACGATTTTAAGGGTTTGGTTTCTAACCTGACTCTCAGTTCCAATA TCCTCACGGACTGGACGATCTTTCCACTGGACACTGAGGATGCAGTGTGCAGCCACCTGGGGGGCTGGGGACACCGTGACAGTGGCCACC ATGATGAAGCCTGGGCCCACAACTCATCCAACTACACGCTCCCGGCCTTTTATATGGGGAACTTCTCCATTCCCAGTGGGATCCCAGACT TGCCCCAGGACACCTTTATCCAGTTTCCTGGATGGACCAAGGGCCAGGTCTGGATTAATGGCTTTAACCTTGGCCGCTATTGGCCAGCCC GGGGCCCTCAGTTGACCTTGTTTGTGCCCCAGCACATCCTGATGACCTCGGCCCCAAACACCATCACCGTGCTGGAACTGGAGTGGGCAC CCTGCAGCAGTGATGATCCAGAACTATGTGCTGTGACGTTCGTGGACAGGCCAGTTATTGGCTCATCTGTGACCTACGATCATCCCTCCA AACCTGTTGAAAAAAGACTCATGCCCCCACCCCCGCAAAAAAACAAAGATTCATGGCTGGACCATGTATGATGATGAAAGCCTGTGTCTT TGAGGGATTCTACCCTGAACATACCTCACAGATCCTCCCTGTCATGCCACATTTCACTGATTGGAATGTGGAAATGGAAAAGGAATTTAG GATGTGCATTTTCACCTGAGGTTTCCCTGCATCCCTGCAGTGCCAAAGCCCCACCTTCAGGGACCACCTGGAATGTGTGAGGGGCTGACA GCACAGTAACGTGCATACATATCTGCAGGGCTGGAATGGAAGCTTTAAAGGTGGTAGTGATTTTTATTTTGGAAGAATCATGTTACCTTT TTGTTAAATAAAATTTGTACTCAAATGATGATGTCACTGTTTTTAATGTGCAGGTATTGAATTATATGGTCTGACTTAAATCATAACTAG >76372_76372_5_RPL28-GLB1_RPL28_chr19_55899416_ENST00000560055_GLB1_chr3_33114206_ENST00000307363_length(amino acids)=760AA_BP=108 MSAHLQWMVVRNCSSFLIKRNKQTYSTEPNNLKARNSFRYNGLIHRKTVGVEPAADGKGVVVVIKRRSGQRKPATSYVRTTINKNARATL SSIRHMIRKNKYRPDLRMNATQRMFEIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQ FSEDHDVEYFLRLAHELGLLVILRPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVEN EYGSYFACDFDYLRFLQKRFRHHLGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGPLINSEFYTGWLDHW GQPHSTIKTEAVASSLYDILARGASVNLYMFIGGTNFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEGPIPP STPKFAYGKVTLEKLKTVGAALDILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDRAYVAVDGIPQGVLER NNVITLNITGKAGATLDLLVENMGRVNYGAYINDFKGLVSNLTLSSNILTDWTIFPLDTEDAVCSHLGGWGHRDSGHHDEAWAHNSSNYT LPAFYMGNFSIPSGIPDLPQDTFIQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPNTITVLELEWAPCSSDDPELCAVT -------------------------------------------------------------- >76372_76372_6_RPL28-GLB1_RPL28_chr19_55899416_ENST00000560583_GLB1_chr3_33114206_ENST00000307363_length(transcript)=3481nt_BP=1085nt CTTTCCGTCTCAGGTCGCCGCTGCGAAGGGAGCCGCCGCCATGTCTGCGCATCTGCAATGGATGGTCGTGCGGAACTGCTCCAGTTTCCT GATCAAGAGGAATAAGCAGACCTACAGCACTGAGCCCAATAACTTGAAGGCCCGCAATTCCTTCCGCTACAACGGACTGATTCACCGCAA GACTGTGGGCGTGGAGCCGGCAGCCGACGGCAAAGGTGTCGTGGTGGTCATTAAGCGGAGATCCGGTGAGCTGGGGTTTGGGGATCAGGC TTGGGGAGACTGGCCAGTGCTGTGGGGAAGGGCCTCCCACTACTGGTTGCAATATGGGCTGGAGAGGGATGGATTCTTGCTTTCAGCCTA CTCCCCACACCCAGCATTGGCCTAGGGGGCGGCTTGTGGAGTGTATGGGCTGAGCCTTGCTCTGCTCCCCCGCCCCCAGGCAGCCATCCG CAGGGCCAGCGCCATCCTGCGCAGCCAGAAGCCTGTGATGGTGAAGAGGAAGCGGACCCGCCCCACCAAGAGCTCCTGAGCCCCCTGCCC CCAGAGCAATAAAGTCAGCTGGCTTTCTCACCTGCCTCGACTGGGCCTCCCTTTTTGAAACGCTCTGGGGAGCTCTGGCCCTGTGTGTTG TCATTCAGGCCATGTCATCAAAACTCTGCATGTCACCTTGTCCATCTGGAGGTGATGTCAATGGCTGGCCATGCAGGAGGGGTGGGGTAG CTGCCTTGTCCCTGGTGAGGGCAAGGGTCACTGTCTTCACAGAAAAAGTTTGCTGACTTGTGATTGAGACCTACTGTCCCATTGTGAGGT GGCCTGAAGAATCCCAGCTGGGGCAGTGGCTTCCATTCAGAAGAAGAAAGGCCTTTTCTAGCCCAGAAGGGTGCAGGCTGAGGGCTGGGC CCTGGGCCCTGGTGCTGTAGCACGGTTTGGGGACTTGGGGTGTTCCCAAGACCTGGGGGACGACAGACATCACGGGAGGAAGATGAGATG ACTTTTGCATCCAGGGAGTGGGTGCAGCCACATTTGGAGGGGATGGGCTTTACTTGATGCAACCTCATCTCTGAGATGGGCAACTTGGTG GGTGGAATGCCACCCAGAGGATGTTTGAAATTGACTATAGCCGGGACTCCTTCCTCAAGGATGGCCAGCCATTTCGCTACATCTCAGGAA GCATTCACTACTCCCGTGTGCCCCGCTTCTACTGGAAGGACCGGCTGCTGAAGATGAAGATGGCTGGGCTGAACGCCATCCAGACGTATG TGCCCTGGAACTTTCATGAGCCCTGGCCAGGACAGTACCAGTTTTCTGAGGACCATGATGTGGAATATTTTCTTCGGCTGGCTCATGAGC TGGGACTGCTGGTTATCCTGAGGCCCGGGCCCTACATCTGTGCAGAGTGGGAAATGGGAGGATTACCTGCTTGGCTGCTAGAGAAAGAGT CTATTCTTCTCCGCTCCTCCGACCCAGATTACCTGGCAGCTGTGGACAAGTGGTTGGGAGTCCTTCTGCCCAAGATGAAGCCTCTCCTCT ATCAGAATGGAGGGCCAGTTATAACAGTGCAGGTTGAAAATGAATATGGCAGCTACTTTGCCTGTGATTTTGACTACCTGCGCTTCCTGC AGAAGCGCTTTCGCCACCATCTGGGGGATGATGTGGTTCTGTTTACCACTGATGGAGCACATAAAACATTCCTGAAATGTGGGGCCCTGC AGGGCCTCTACACCACGGTGGACTTTGGAACAGGCAGCAACATCACAGATGCTTTCCTAAGCCAGAGGAAGTGTGAGCCCAAAGGACCCT TGATCAATTCTGAATTCTATACTGGCTGGCTAGATCACTGGGGCCAACCTCACTCCACAATCAAGACCGAAGCAGTGGCTTCCTCCCTCT ATGATATACTTGCCCGTGGGGCGAGTGTGAACTTGTACATGTTTATAGGTGGGACCAATTTTGCCTATTGGAATGGGGCCAACTCACCCT ATGCAGCACAGCCCACCAGCTACGACTATGATGCCCCACTGAGTGAGGCTGGGGACCTCACTGAGAAGTATTTTGCTCTGCGAAACATCA TCCAGAAGTTTGAAAAAGTACCAGAAGGTCCTATCCCTCCATCTACACCAAAGTTTGCATATGGAAAGGTCACTTTGGAAAAGTTAAAGA CAGTGGGAGCAGCTCTGGACATTCTGTGTCCCTCTGGGCCCATCAAAAGCCTTTATCCCTTGACATTTATCCAGGTGAAACAGCATTATG GGTTTGTGCTGTACCGGACAACACTTCCTCAAGATTGCAGCAACCCAGCACCTCTCTCTTCACCCCTCAATGGAGTCCACGATCGAGCAT ATGTTGCTGTGGATGGGATCCCCCAGGGAGTCCTTGAGCGAAACAATGTGATCACTCTGAACATAACAGGGAAAGCTGGAGCCACTCTGG ACCTTCTGGTAGAGAACATGGGACGTGTGAACTATGGTGCATATATCAACGATTTTAAGGGTTTGGTTTCTAACCTGACTCTCAGTTCCA ATATCCTCACGGACTGGACGATCTTTCCACTGGACACTGAGGATGCAGTGTGCAGCCACCTGGGGGGCTGGGGACACCGTGACAGTGGCC ACCATGATGAAGCCTGGGCCCACAACTCATCCAACTACACGCTCCCGGCCTTTTATATGGGGAACTTCTCCATTCCCAGTGGGATCCCAG ACTTGCCCCAGGACACCTTTATCCAGTTTCCTGGATGGACCAAGGGCCAGGTCTGGATTAATGGCTTTAACCTTGGCCGCTATTGGCCAG CCCGGGGCCCTCAGTTGACCTTGTTTGTGCCCCAGCACATCCTGATGACCTCGGCCCCAAACACCATCACCGTGCTGGAACTGGAGTGGG CACCCTGCAGCAGTGATGATCCAGAACTATGTGCTGTGACGTTCGTGGACAGGCCAGTTATTGGCTCATCTGTGACCTACGATCATCCCT CCAAACCTGTTGAAAAAAGACTCATGCCCCCACCCCCGCAAAAAAACAAAGATTCATGGCTGGACCATGTATGATGATGAAAGCCTGTGT CTTTGAGGGATTCTACCCTGAACATACCTCACAGATCCTCCCTGTCATGCCACATTTCACTGATTGGAATGTGGAAATGGAAAAGGAATT TAGGATGTGCATTTTCACCTGAGGTTTCCCTGCATCCCTGCAGTGCCAAAGCCCCACCTTCAGGGACCACCTGGAATGTGTGAGGGGCTG ACAGCACAGTAACGTGCATACATATCTGCAGGGCTGGAATGGAAGCTTTAAAGGTGGTAGTGATTTTTATTTTGGAAGAATCATGTTACC TTTTTGTTAAATAAAATTTGTACTCAAATGATGATGTCACTGTTTTTAATGTGCAGGTATTGAATTATATGGTCTGACTTAAATCATAAC >76372_76372_6_RPL28-GLB1_RPL28_chr19_55899416_ENST00000560583_GLB1_chr3_33114206_ENST00000307363_length(amino acids)=647AA_BP= MFEIDYSRDSFLKDGQPFRYISGSIHYSRVPRFYWKDRLLKMKMAGLNAIQTYVPWNFHEPWPGQYQFSEDHDVEYFLRLAHELGLLVIL RPGPYICAEWEMGGLPAWLLEKESILLRSSDPDYLAAVDKWLGVLLPKMKPLLYQNGGPVITVQVENEYGSYFACDFDYLRFLQKRFRHH LGDDVVLFTTDGAHKTFLKCGALQGLYTTVDFGTGSNITDAFLSQRKCEPKGPLINSEFYTGWLDHWGQPHSTIKTEAVASSLYDILARG ASVNLYMFIGGTNFAYWNGANSPYAAQPTSYDYDAPLSEAGDLTEKYFALRNIIQKFEKVPEGPIPPSTPKFAYGKVTLEKLKTVGAALD ILCPSGPIKSLYPLTFIQVKQHYGFVLYRTTLPQDCSNPAPLSSPLNGVHDRAYVAVDGIPQGVLERNNVITLNITGKAGATLDLLVENM GRVNYGAYINDFKGLVSNLTLSSNILTDWTIFPLDTEDAVCSHLGGWGHRDSGHHDEAWAHNSSNYTLPAFYMGNFSIPSGIPDLPQDTF IQFPGWTKGQVWINGFNLGRYWPARGPQLTLFVPQHILMTSAPNTITVLELEWAPCSSDDPELCAVTFVDRPVIGSSVTYDHPSKPVEKR -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for RPL28-GLB1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for RPL28-GLB1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for RPL28-GLB1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | RPL28 | C0043094 | Weight Gain | 1 | CTD_human |
| Tgene | C0268271 | Gangliosidosis, Generalized GM1, Type 1 (disorder) | 21 | CTD_human;GENOMICS_ENGLAND;UNIPROT | |
| Tgene | C0268272 | Gangliosidosis, Generalized GM1, Type 2 | 14 | CTD_human;GENOMICS_ENGLAND;UNIPROT | |
| Tgene | C0268273 | Gangliosidosis, Generalized GM1, Type 3 | 13 | CTD_human;GENOMICS_ENGLAND;UNIPROT | |
| Tgene | C0086652 | Mucopolysaccharidosis type IVB | 12 | CTD_human;GENOMICS_ENGLAND;UNIPROT | |
| Tgene | C0026707 | Mucopolysaccharidosis IV | 4 | CTD_human;GENOMICS_ENGLAND | |
| Tgene | C0086651 | Mucopolysaccharidosis, MPS-IV-A | 2 | CTD_human | |
| Tgene | C3179194 | GALNS Deficiency | 2 | CTD_human | |
| Tgene | C0005941 | Bone Diseases, Developmental | 1 | CTD_human | |
| Tgene | C0010038 | Corneal Opacity | 1 | CTD_human | |
| Tgene | C0011615 | Dermatitis, Atopic | 1 | CTD_human | |
| Tgene | C0011616 | Contact Dermatitis | 1 | CTD_human | |
| Tgene | C0013366 | Dyschondroplasias | 1 | CTD_human | |
| Tgene | C0025237 | Melnick-Needles Syndrome | 1 | CTD_human | |
| Tgene | C0026760 | Multiple Epiphyseal Dysplasia | 1 | CTD_human | |
| Tgene | C0029422 | Osteochondrodysplasias | 1 | CTD_human | |
| Tgene | C0036391 | Schwartz-Jampel Syndrome | 1 | CTD_human | |
| Tgene | C0036572 | Seizures | 1 | GENOMICS_ENGLAND | |
| Tgene | C0038015 | Spondyloepiphyseal Dysplasia | 1 | CTD_human | |
| Tgene | C0086196 | Eczema, Infantile | 1 | CTD_human | |
| Tgene | C0162351 | Contact hypersensitivity | 1 | CTD_human | |
| Tgene | C0432272 | Van Buchem disease | 1 | CTD_human | |
| Tgene | C3541456 | Spondyloepiphyseal Dysplasia Tarda, X-Linked | 1 | CTD_human | |
| Tgene | C4551479 | Schwartz-Jampel Syndrome, Type 1 | 1 | CTD_human |
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