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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ARAP3-CTBP2 (FusionGDB2 ID:HG64411TG1488)

Fusion Gene Summary for ARAP3-CTBP2

check button Fusion gene summary
Fusion gene informationFusion gene name: ARAP3-CTBP2
Fusion gene ID: hg64411tg1488
HgeneTgene
Gene symbol

ARAP3

CTBP2

Gene ID

64411

1488

Gene nameArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3C-terminal binding protein 2
SynonymsCENTD3|DRAG1-
Cytomap('ARAP3')('CTBP2')

5q31.3

10q26.13

Type of geneprotein-codingprotein-coding
Descriptionarf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3ARF-GAP, RHO-GAP, ankyrin repeat and plekstrin homology domains-containing protein 3Arf and Rho GAP adapter protein 3PtdIns(3,4,5)P3-binding proteincentaurin-delta-3phosphoinosC-terminal-binding protein 2ribeye
Modification date2020032720200313
UniProtAcc.

P56545

Ensembl transtripts involved in fusion geneENST00000239440, ENST00000508305, 
ENST00000513878, ENST00000512390, 
Fusion gene scores* DoF score3 X 3 X 3=2711 X 9 X 4=396
# samples 313
** MAII scorelog2(3/27*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
log2(13/396*10)=-1.60698880705116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ARAP3 [Title/Abstract] AND CTBP2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointARAP3(141045991)-CTBP2(126678267), # samples:2
Anticipated loss of major functional domain due to fusion event.ARAP3-CTBP2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ARAP3-CTBP2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ARAP3-CTBP2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ARAP3-CTBP2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ARAP3-CTBP2 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
ARAP3-CTBP2 seems lost the major protein functional domain in Tgene partner, which is a epigenetic factor due to the frame-shifted ORF.
ARAP3-CTBP2 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ARAP3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across CTBP2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4UCECTCGA-AP-A5FX-01AARAP3chr5

141045991

-CTBP2chr10

126678267

-


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Fusion Gene ORF analysis for ARAP3-CTBP2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000239440ENST00000309035ARAP3chr5

141045991

-CTBP2chr10

126678267

-
5CDS-intronENST00000239440ENST00000334808ARAP3chr5

141045991

-CTBP2chr10

126678267

-
5CDS-intronENST00000239440ENST00000476817ARAP3chr5

141045991

-CTBP2chr10

126678267

-
5CDS-intronENST00000508305ENST00000309035ARAP3chr5

141045991

-CTBP2chr10

126678267

-
5CDS-intronENST00000508305ENST00000334808ARAP3chr5

141045991

-CTBP2chr10

126678267

-
5CDS-intronENST00000508305ENST00000476817ARAP3chr5

141045991

-CTBP2chr10

126678267

-
5CDS-intronENST00000513878ENST00000309035ARAP3chr5

141045991

-CTBP2chr10

126678267

-
5CDS-intronENST00000513878ENST00000334808ARAP3chr5

141045991

-CTBP2chr10

126678267

-
5CDS-intronENST00000513878ENST00000476817ARAP3chr5

141045991

-CTBP2chr10

126678267

-
5UTR-3CDSENST00000512390ENST00000337195ARAP3chr5

141045991

-CTBP2chr10

126678267

-
5UTR-3CDSENST00000512390ENST00000411419ARAP3chr5

141045991

-CTBP2chr10

126678267

-
5UTR-3CDSENST00000512390ENST00000494626ARAP3chr5

141045991

-CTBP2chr10

126678267

-
5UTR-3CDSENST00000512390ENST00000531469ARAP3chr5

141045991

-CTBP2chr10

126678267

-
5UTR-intronENST00000512390ENST00000309035ARAP3chr5

141045991

-CTBP2chr10

126678267

-
5UTR-intronENST00000512390ENST00000334808ARAP3chr5

141045991

-CTBP2chr10

126678267

-
5UTR-intronENST00000512390ENST00000476817ARAP3chr5

141045991

-CTBP2chr10

126678267

-
Frame-shiftENST00000239440ENST00000337195ARAP3chr5

141045991

-CTBP2chr10

126678267

-
Frame-shiftENST00000239440ENST00000411419ARAP3chr5

141045991

-CTBP2chr10

126678267

-
Frame-shiftENST00000239440ENST00000531469ARAP3chr5

141045991

-CTBP2chr10

126678267

-
Frame-shiftENST00000508305ENST00000494626ARAP3chr5

141045991

-CTBP2chr10

126678267

-
Frame-shiftENST00000513878ENST00000494626ARAP3chr5

141045991

-CTBP2chr10

126678267

-
In-frameENST00000239440ENST00000494626ARAP3chr5

141045991

-CTBP2chr10

126678267

-
In-frameENST00000508305ENST00000337195ARAP3chr5

141045991

-CTBP2chr10

126678267

-
In-frameENST00000508305ENST00000411419ARAP3chr5

141045991

-CTBP2chr10

126678267

-
In-frameENST00000508305ENST00000531469ARAP3chr5

141045991

-CTBP2chr10

126678267

-
In-frameENST00000513878ENST00000337195ARAP3chr5

141045991

-CTBP2chr10

126678267

-
In-frameENST00000513878ENST00000411419ARAP3chr5

141045991

-CTBP2chr10

126678267

-
In-frameENST00000513878ENST00000531469ARAP3chr5

141045991

-CTBP2chr10

126678267

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000508305ARAP3chr5141045991-ENST00000337195CTBP2chr10126678267-43752528342610858
ENST00000508305ARAP3chr5141045991-ENST00000531469CTBP2chr10126678267-30022528342610858
ENST00000508305ARAP3chr5141045991-ENST00000411419CTBP2chr10126678267-30022528342610858
ENST00000239440ARAP3chr5141045991-ENST00000494626CTBP2chr10126678267-31122638662720884
ENST00000513878ARAP3chr5141045991-ENST00000337195CTBP2chr10126678267-34741627541709551
ENST00000513878ARAP3chr5141045991-ENST00000531469CTBP2chr10126678267-21011627541709551
ENST00000513878ARAP3chr5141045991-ENST00000411419CTBP2chr10126678267-21011627541709551

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000508305ENST00000337195ARAP3chr5141045991-CTBP2chr10126678267-0.0041157980.9958841
ENST00000508305ENST00000531469ARAP3chr5141045991-CTBP2chr10126678267-0.0153524990.9846475
ENST00000508305ENST00000411419ARAP3chr5141045991-CTBP2chr10126678267-0.0153524990.9846475
ENST00000239440ENST00000494626ARAP3chr5141045991-CTBP2chr10126678267-0.0142286510.9857714
ENST00000513878ENST00000337195ARAP3chr5141045991-CTBP2chr10126678267-0.055594940.9444051
ENST00000513878ENST00000531469ARAP3chr5141045991-CTBP2chr10126678267-0.208506640.7914934
ENST00000513878ENST00000411419ARAP3chr5141045991-CTBP2chr10126678267-0.208506640.7914934

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Fusion Genomic Features for ARAP3-CTBP2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for ARAP3-CTBP2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:141045991/chr10:126678267)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.CTBP2

P56545

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity). {ECO:0000250}.; FUNCTION: Isoform 2 probably acts as a scaffold for specialized synapses.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneARAP3chr5:141045991chr10:126678267ENST00000239440-173381_1398571545.0Compositional biasNote=Pro-rich
HgeneARAP3chr5:141045991chr10:126678267ENST00000239440-1733287_3798571545.0DomainPH 1
HgeneARAP3chr5:141045991chr10:126678267ENST00000239440-1733394_4838571545.0DomainPH 2
HgeneARAP3chr5:141045991chr10:126678267ENST00000239440-1733480_6118571545.0DomainArf-GAP
HgeneARAP3chr5:141045991chr10:126678267ENST00000239440-17334_688571545.0DomainSAM
HgeneARAP3chr5:141045991chr10:126678267ENST00000239440-1733504_5278571545.0Zinc fingerC4-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneARAP3chr5:141045991chr10:126678267ENST00000239440-17331462_15428571545.0Compositional biasNote=Pro-rich
HgeneARAP3chr5:141045991chr10:126678267ENST00000239440-17331117_12108571545.0DomainRas-associating
HgeneARAP3chr5:141045991chr10:126678267ENST00000239440-17331223_13258571545.0DomainPH 3
HgeneARAP3chr5:141045991chr10:126678267ENST00000239440-1733907_10888571545.0DomainRho-GAP
TgeneCTBP2chr5:141045991chr10:126678267ENST0000030903579186_191925986.0Nucleotide bindingNAD
TgeneCTBP2chr5:141045991chr10:126678267ENST0000030903579243_249925986.0Nucleotide bindingNAD
TgeneCTBP2chr5:141045991chr10:126678267ENST0000030903579270_272925986.0Nucleotide bindingNAD
TgeneCTBP2chr5:141045991chr10:126678267ENST0000030903579321_324925986.0Nucleotide bindingNAD
TgeneCTBP2chr5:141045991chr10:126678267ENST00000337195911186_191385446.0Nucleotide bindingNAD
TgeneCTBP2chr5:141045991chr10:126678267ENST00000337195911243_249385446.0Nucleotide bindingNAD
TgeneCTBP2chr5:141045991chr10:126678267ENST00000337195911270_272385446.0Nucleotide bindingNAD
TgeneCTBP2chr5:141045991chr10:126678267ENST00000337195911321_324385446.0Nucleotide bindingNAD
TgeneCTBP2chr5:141045991chr10:126678267ENST00000411419911186_191385446.0Nucleotide bindingNAD
TgeneCTBP2chr5:141045991chr10:126678267ENST00000411419911243_249385446.0Nucleotide bindingNAD
TgeneCTBP2chr5:141045991chr10:126678267ENST00000411419911270_272385446.0Nucleotide bindingNAD
TgeneCTBP2chr5:141045991chr10:126678267ENST00000411419911321_324385446.0Nucleotide bindingNAD
TgeneCTBP2chr5:141045991chr10:126678267ENST00000494626911186_191385446.0Nucleotide bindingNAD
TgeneCTBP2chr5:141045991chr10:126678267ENST00000494626911243_249385446.0Nucleotide bindingNAD
TgeneCTBP2chr5:141045991chr10:126678267ENST00000494626911270_272385446.0Nucleotide bindingNAD
TgeneCTBP2chr5:141045991chr10:126678267ENST00000494626911321_324385446.0Nucleotide bindingNAD
TgeneCTBP2chr5:141045991chr10:126678267ENST00000531469911186_191385446.0Nucleotide bindingNAD
TgeneCTBP2chr5:141045991chr10:126678267ENST00000531469911243_249385446.0Nucleotide bindingNAD
TgeneCTBP2chr5:141045991chr10:126678267ENST00000531469911270_272385446.0Nucleotide bindingNAD
TgeneCTBP2chr5:141045991chr10:126678267ENST00000531469911321_324385446.0Nucleotide bindingNAD


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Fusion Gene Sequence for ARAP3-CTBP2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>5773_5773_1_ARAP3-CTBP2_ARAP3_chr5_141045991_ENST00000239440_CTBP2_chr10_126678267_ENST00000494626_length(transcript)=3112nt_BP=2638nt
CTCGGACGAGCGGCGGGCACCCGCGAGCGGACGGCGGCCGCGTAGTGAGCAATGGCCTGAGCCCCCATGGCTGCCCCTCAGGACCTGGAC
ATCGCTGTGTGGCTGGCCACGGTGCACCTGGAGCAGTATGCAGACACGTTCCGACGGCATGGCCTGGCTACAGCAGGTGCAGCCCGGGGC
CTGGGCCACGAGGAGTTGAAGCAGTTGGGCATCAGCGCCACAGGGCACCGGAAACGCATTCTACGCCTGCTACAGACAGGCACCGAAGAG
GGCTCCCTGGATCCCAAATCAGATAGTGCCATGGAACCATCCCCCAGCCCAGCCCCGCAAGCCCAGCCCCCTAAGCCCGTGCCGAAGCCC
AGGACCGTGTTTGGTGGACTCAGTGGCCCTGCCACCACTCAGAGACCTGGGCTGAGCCCAGCCCTCGGGGGACCAGGAGTGTCCAGGAGC
CCAGAGCCCAGCCCAAGGCCTCCTCCTCTCCCCACTTCCTCCTCTGAGCAGTCTTCAGCCCTAAATACTGTGGAGATGATGCCTAATTCC
ATCTACTTCGGCCTGGACTCAAGAGGCAGGGCACAGGCAGCTCAGGACAAGGCCCCAGACAGCTCCCAAATCTCTGCCCCCACCCCTGCC
CTCAGGCCCACAACAGGCACAGTGCACATCATGGATCCTGGTTGCCTGTACTATGGTGTCCAACCTGTGGGGACTCCAGGAGCCCCCGAC
AGAAGAGAGAGCAGAGGTGTTTGTCAGGGCAGGGCTGAACACAGGCTCAGCAGACAGGATCTGGAGGCACGGGAGGATGCTGGCTATGCC
AGCCTTGAGCTACCTGGAGACTCCACCCTCTTATCGCCCACCCTGGAAACAGAGGAGACCAGTGATGACCTCATTTCACCCTATGCCAGC
TTCTCCTTCACGGCAGACCGCCTCACGCCCCTGCTCAGTGGCTGGCTAGACAAGCTCTCCCCTCAGGGAAACTATGTCTTCCAGAGACGC
TTTGTGCAGTTCAATGGGAGGAGTCTGATGTACTTTGGCAGTGACAAGGACCCCTTCCCTAAGGGTGTGATACCTTTGACTGCCATTGAG
ATGACCCGCAGCAGCAAGGACAACAAGTTCCAGGTCATCACCGGCCAGAGGGTGTTCGTGTTCCGCACAGAGAGCGAGGCTCAGCGGGAC
ATGTGGTGCTCCACGCTGCAGTCCTGTCTGAAGGAGCAGCGCCTCCTGGGCCACCCCCGGCCCCCCCAACCACCCCGACCCCTCCGCACG
GGCATGCTGGAGCTGCGTGGACACAAGGCCAAGGTGTTTGCTGCCTTGAGCCCTGGAGAGCTGGCACTGTACAAGAGTGAGCAGGCCTTC
TCTCTGGGCATCGGGATCTGCTTCATCGAACTGCAGGGCTGCAGCGTCCGGGAGACCAAGAGTCGAAGCTTTGACCTGCTCACACCCCAT
CGCTGCTTCAGCTTCACAGCCGAGTCTGGGGGTGCTCGGCAGAGCTGGGCGGCCGCTCTGCAGGAAGCAGTAACCGAGACCCTGTCTGAC
TACGAGGTGGCTGAGAAGATCTGGTCTAATCGGGCCAACCGGCAGTGTGCGGACTGTGGGTCCTCCCGCCCAGATTGGGCTGCTGTCAAT
TTGGGGGTGGTCATCTGCAAGCAGTGTGCAGGTCAGCACCGGGCCCTGGGTTCTGGGATCTCCAAGGTGCAGAGCCTGAAGCTGGACACG
AGTGTCTGGAGTAATGAGATAGTACAGTTATTCATTGTCCTGGGAAATGATCGTGCCAACCGCTTCTGGGCAGGGACCCTACCCCCAGGT
GAGGGACTACATCCAGATGCGACCCCTGGCCCCCGGGGAGAGTTCATCTCCCGAAAGTACCGTCTGGGTCTCTTCCGGAAGCCCCACCCT
CAGTACCCAGATCATAGCCAGCTTCTCCAGGCACTGTGTGCAGCTGTGGCAAGACCCAACCTGCTGAAGAACATGACCCAGCTCCTCTGT
GTTGAGGCCTTTGAAGGCGAGGAGCCCTGGTTCCCCCCAGCCCCTGATGGCAGCTGCCCTGGCCTCTTGCCCTCAGACCCCTCCCCTGGT
GTGTACAATGAGGTGGTGGTGCGTGCTACTTACAGCGGCTTCCTGTACTGCAGTCCCGTCAGCAACAAAGCTGGACCCTCACCCCCTCGC
AGGGGCCGGGATGCTCCCCCGCGCCTTTGGTGTGTGCTGGGAGCAGCTCTGGAAATGTTTGCATCGGAAAACAGCCCTGAACCCCTCAGC
CTCATACAGCCCCAGGATATTGTATGTCTGGGTGTGAGCCCCCCACCCACTGACCCAGGTGACAGGTTCCCCTTTTCCTTTGAGCTCATC
CTCGCTGGGGGGAGGATCCAGCATTTTGGCACAGATGGAGCTGACAGTCTGGAGGCCTGGACTAGTGCTGTGGGCAAGTGGTTCTCCCCG
CTGAGCTGCCACCAGCTGCTGGGCCCCGGGCTGCTGCGGCTGGGCCGCCTATGGCTGCGGTCCCCCTCCCATACAGCCCCGGCCCCTGGT
CTCTGGCTGTCAGGGTTTGGCCTCCTTCGTGGTGACCACCTCTTCCTGTGCTCAGCGCCGGGCCCAGGCCCCCCAGCCCCTGAGGACATG
GTGCATCTGCGGCGGCTACAGGAGATCAATATCCGCCAGGCATCGTGGGTGTGGCTCCAGGAGGACTTCCTGCAGCCATGGAAGGGATCA
TCCCTGGAGGCATCCCAGTGACTCACAACCTCCCGACAGTGGCACATCCTTCCCAAGCGCCCTCTCCCAACCAGCCCACAAAACACGGGG
ACAATCGAGAGCACCCCAACGAGCAATAGCAGAGAATGCCAGAAGGTAATCACTCAGATACACTTGGGACCAAGAGACAGTGAAAAATAG
ATGAACTAAGAGAAAAAGAATCGGATGGTCTTTGTAACTGATTCTGGACATATGCATCATTGATGTTGCAGTGTTGAAACTACAAGAGCT
AGAAAACTGAAGATGTCGTCTGCTTACGGAAGCGCTGAAAGACTAGGATGTGATTTATTAACGACCAACTTCTGTTATTGTGTGTTAAGT

>5773_5773_1_ARAP3-CTBP2_ARAP3_chr5_141045991_ENST00000239440_CTBP2_chr10_126678267_ENST00000494626_length(amino acids)=884AA_BP=858
MAAPQDLDIAVWLATVHLEQYADTFRRHGLATAGAARGLGHEELKQLGISATGHRKRILRLLQTGTEEGSLDPKSDSAMEPSPSPAPQAQ
PPKPVPKPRTVFGGLSGPATTQRPGLSPALGGPGVSRSPEPSPRPPPLPTSSSEQSSALNTVEMMPNSIYFGLDSRGRAQAAQDKAPDSS
QISAPTPALRPTTGTVHIMDPGCLYYGVQPVGTPGAPDRRESRGVCQGRAEHRLSRQDLEAREDAGYASLELPGDSTLLSPTLETEETSD
DLISPYASFSFTADRLTPLLSGWLDKLSPQGNYVFQRRFVQFNGRSLMYFGSDKDPFPKGVIPLTAIEMTRSSKDNKFQVITGQRVFVFR
TESEAQRDMWCSTLQSCLKEQRLLGHPRPPQPPRPLRTGMLELRGHKAKVFAALSPGELALYKSEQAFSLGIGICFIELQGCSVRETKSR
SFDLLTPHRCFSFTAESGGARQSWAAALQEAVTETLSDYEVAEKIWSNRANRQCADCGSSRPDWAAVNLGVVICKQCAGQHRALGSGISK
VQSLKLDTSVWSNEIVQLFIVLGNDRANRFWAGTLPPGEGLHPDATPGPRGEFISRKYRLGLFRKPHPQYPDHSQLLQALCAAVARPNLL
KNMTQLLCVEAFEGEEPWFPPAPDGSCPGLLPSDPSPGVYNEVVVRATYSGFLYCSPVSNKAGPSPPRRGRDAPPRLWCVLGAALEMFAS
ENSPEPLSLIQPQDIVCLGVSPPPTDPGDRFPFSFELILAGGRIQHFGTDGADSLEAWTSAVGKWFSPLSCHQLLGPGLLRLGRLWLRSP

--------------------------------------------------------------
>5773_5773_2_ARAP3-CTBP2_ARAP3_chr5_141045991_ENST00000508305_CTBP2_chr10_126678267_ENST00000337195_length(transcript)=4375nt_BP=2528nt
ACCCGCGAGCGGACGGCGGCCGCGTAGTGAGGACCTGGACATCGCTGTGTGGCTGGCCACGGTGCACCTGGAGCAGTATGCAGACACGTT
CCGACGGCATGGCCTGGCTACAGCAGGTGCAGCCCGGGGCCTGGGCCACGAGGAGTTGAAGCAGTTGGGCATCAGCGCCACAGGGCACCG
GAAACGCATTCTACGCCTGCTACAGACAGGCACCGAAGAGGGCTCCCTGGATCCCAAATCAGATAGTGCCATGGAACCATCCCCCAGCCC
AGCCCCGCAAGCCCAGCCCCCTAAGCCCGTGCCGAAGCCCAGGACCGTGTTTGGTGGACTCAGTGGCCCTGCCACCACTCAGAGACCTGG
GCTGAGCCCAGCCCTCGGGGGACCAGGAGTGTCCAGGAGCCCAGAGCCCAGCCCAAGGCCTCCTCCTCTCCCCACTTCCTCCTCTGAGCA
GTCTTCAGCCCTAAATACTGTGGAGATGATGCCTAATTCCATCTACTTCGGCCTGGACTCAAGAGGCAGGGCACAGGCAGCTCAGGACAA
GGCCCCAGACAGCTCCCAAATCTCTGCCCCCACCCCTGCCCTCAGGCCCACAACAGGCACAGTGCACATCATGGATCCTGGTTGCCTGTA
CTATGGTGTCCAACCTGTGGGGACTCCAGGAGCCCCCGACAGAAGAGAGAGCAGAGGTGTTTGTCAGGGCAGGGCTGAACACAGGCTCAG
CAGACAGGATCTGGAGGCACGGGAGGATGCTGGCTATGCCAGCCTTGAGCTACCTGGAGACTCCACCCTCTTATCGCCCACCCTGGAAAC
AGAGGAGACCAGTGATGACCTCATTTCACCCTATGCCAGCTTCTCCTTCACGGCAGACCGCCTCACGCCCCTGCTCAGTGGCTGGCTAGA
CAAGCTCTCCCCTCAGGGAAACTATGTCTTCCAGAGACGCTTTGTGCAGTTCAATGGGAGGAGTCTGATGTACTTTGGCAGTGACAAGGA
CCCCTTCCCTAAGGGTGTGATACCTTTGACTGCCATTGAGATGACCCGCAGCAGCAAGGACAACAAGTTCCAGGTCATCACCGGCCAGAG
GGTGTTCGTGTTCCGCACAGAGAGCGAGGCTCAGCGGGACATGTGGTGCTCCACGCTGCAGTCCTGTCTGAAGGAGCAGCGCCTCCTGGG
CCACCCCCGGCCCCCCCAACCACCCCGACCCCTCCGCACGGGCATGCTGGAGCTGCGTGGACACAAGGCCAAGGTGTTTGCTGCCTTGAG
CCCTGGAGAGCTGGCACTGTACAAGAGTGAGCAGGCCTTCTCTCTGGGCATCGGGATCTGCTTCATCGAACTGCAGGGCTGCAGCGTCCG
GGAGACCAAGAGTCGAAGCTTTGACCTGCTCACACCCCATCGCTGCTTCAGCTTCACAGCCGAGTCTGGGGGTGCTCGGCAGAGCTGGGC
GGCCGCTCTGCAGGAAGCAGTAACCGAGACCCTGTCTGACTACGAGGTGGCTGAGAAGATCTGGTCTAATCGGGCCAACCGGCAGTGTGC
GGACTGTGGGTCCTCCCGCCCAGATTGGGCTGCTGTCAATTTGGGGGTGGTCATCTGCAAGCAGTGTGCAGGTCAGCACCGGGCCCTGGG
TTCTGGGATCTCCAAGGTGCAGAGCCTGAAGCTGGACACGAGTGTCTGGAGTAATGAGATAGTACAGTTATTCATTGTCCTGGGAAATGA
TCGTGCCAACCGCTTCTGGGCAGGGACCCTACCCCCAGGTGAGGGACTACATCCAGATGCGACCCCTGGCCCCCGGGGAGAGTTCATCTC
CCGAAAGTACCGTCTGGGTCTCTTCCGGAAGCCCCACCCTCAGTACCCAGATCATAGCCAGCTTCTCCAGGCACTGTGTGCAGCTGTGGC
AAGACCCAACCTGCTGAAGAACATGACCCAGCTCCTCTGTGTTGAGGCCTTTGAAGACCCCTCCCCTGGTGTGTACAATGAGGTGGTGGT
GCGTGCTACTTACAGCGGCTTCCTGTACTGCAGTCCCGTCAGCAACAAAGCTGGACCCTCACCCCCTCGCAGGGGCCGGGATGCTCCCCC
GCGCCTTTGGTGTGTGCTGGGAGCAGCTCTGGAAATGTTTGCATCGGAAAACAGCCCTGAACCCCTCAGCCTCATACAGCCCCAGGATAT
TGTATGTCTGGGTGTGAGCCCCCCACCCACTGACCCAGGTGACAGGTTCCCCTTTTCCTTTGAGCTCATCCTCGCTGGGGGGAGGATCCA
GCATTTTGGCACAGATGGAGCTGACAGTCTGGAGGCCTGGACTAGTGCTGTGGGCAAGTGGTTCTCCCCGCTGAGCTGCCACCAGCTGCT
GGGCCCCGGGCTGCTGCGGCTGGGCCGCCTATGGCTGCGGTCCCCCTCCCATACAGCCCCGGCCCCTGGTCTCTGGCTGTCAGGGTTTGG
CCTCCTTCGTGGTGACCACCTCTTCCTGTGCTCAGCGCCGGGCCCAGGCCCCCCAGCCCCTGAGGACATGGTGCATCTGCGGCGGCTACA
GGAGATCAATATCCGCCAGGCATCGTGGGTGTGGCTCCAGGAGGACTTCCTGCAGCCATGGAAGGGATCATCCCTGGAGGCATCCCAGTG
ACTCACAACCTCCCGACAGTGGCACATCCTTCCCAAGCGCCCTCTCCCAACCAGCCCACAAAACACGGGGACAATCGAGAGCACCCCAAC
GAGCAATAGCAGAGAATGCCAGAAGGTAATCACTCAGATACACTTGGGACCAAGAGACAGTGAAAAATAGATGAACTAAGAGAAAAAGAA
TCGGATGGTCTTTGTAACTGATTCTGGACATATGCATCATTGATGTTGCAGTGTTGAAACTACAAGAGCTAGAAAACTGAAGATGTCGTC
TGCTTACGGAAGCGCTGAAAGACTAGGATGTGATTTATTAACGACCAACTTCTGTTATTGTGTGTTAAGTTTTTCATCTGTGCATCAAAT
CACAAAAAGAATAAATAGAGCTTTTTCCTTTATCAGTCCCTTGGGCACAGCAGGTCCTGAACACCCTGCTCTACAATGTTGCATCAAGAG
TTCAAACAACAAAATAAAAAATATTAAGAGGAAATCCCCATCCTGTGACTTGAGTCCCTTAAGTCTACAGGGGCTGGTGACCTCTTTTTG
CTAATAGGAAAATCACATTACTACAAAATGGGGAGAAAACTGTTTGCCTGTGGTAGACACCTGCACGCATAGGATTGAAGACAGTACAGG
CTGCTGTACAGAGAAGCGCCTCTCACATCTGAACTGCATACTGAGCGGGCAAGTCGGTTGTAAGTTCAGTAAAACCCTCTGATGATGCAA
AAAAAAAAAAAAAAGTATTAAGTTTCACAAGCTGTTTGTACTCAAATATATTTTCTCAGTTTCAGATCCTCTGCTATTTTATTGAGTGGA
AAGTCTTGAGCTAAAAGGGTTCAAGAAGAATAATGTTGCATTTCCTTATGTCTCAGGAAACACTTTTTATGGTAACTTGTCAGATTGTCT
ATGAACAAACCCACTTTTTTAGACATTGATAAAGTCTTCTTTTCTTCACGTGATATTTTATACAAGAACACTTCAGATGTATTAGATGTG
ACTGATTTTAACAAATCCTATTAGATTTGTATCAACTAGTTACATGTTCTATTCATAGTCTTTTGTGAATCATTGCCTTTTTGTTTAAAA
AGATGGCCTATTTTGAGCCTTTGTATAGGTACATTCCTGTTTTTGTGACAAAAGAAAAACTTTAAAATTGTCCCAAACAGAAAAATAATG
GCTATCAGAAGTATGTTTTGTTTTAGTGTGAGTTACCGTTACTGTATTTGTTTATTGTAAAGGTGGACATTTAGCGTTCAGTGCAGTTTT
CAATAAAAAGTAATTAAAATTTGTTAAGTTCTGAAATTCAAGTACATCTCACTAATGTAAATGTTCTCTACTTGAGATGTTTAAGGCAAT
TGCATTGTCAATTAGCCAATTTCCAGCTCTTGTTACTACAGGGTTCCATAACCAGACTCAAGACCGCTGACAATTAATTACCTGTGATAA
CAAAAAGTTTAATTGAAAAATCAAAACCTCACACAAGTCCATCATTATCACGTCATGCCATCCTTAAGATGCAATGGTGGGTTAGTGCTA
AATCAATTCAAAAAAAAACAAAGTTGCTCAACTTTTAGAGTTCTGACTTTAATCTACCCCAAAGCAAAATGACCTGGACCTGGTTCAAGG
GAGGGAAGTGAACCTTGAAACTGTTTTGCCAATAACCTAACAAACAAAATGATATTTACAAAGAAGTGTTGCAAATAGTCCCATGAGTTA

>5773_5773_2_ARAP3-CTBP2_ARAP3_chr5_141045991_ENST00000508305_CTBP2_chr10_126678267_ENST00000337195_length(amino acids)=858AA_BP=832
MDIAVWLATVHLEQYADTFRRHGLATAGAARGLGHEELKQLGISATGHRKRILRLLQTGTEEGSLDPKSDSAMEPSPSPAPQAQPPKPVP
KPRTVFGGLSGPATTQRPGLSPALGGPGVSRSPEPSPRPPPLPTSSSEQSSALNTVEMMPNSIYFGLDSRGRAQAAQDKAPDSSQISAPT
PALRPTTGTVHIMDPGCLYYGVQPVGTPGAPDRRESRGVCQGRAEHRLSRQDLEAREDAGYASLELPGDSTLLSPTLETEETSDDLISPY
ASFSFTADRLTPLLSGWLDKLSPQGNYVFQRRFVQFNGRSLMYFGSDKDPFPKGVIPLTAIEMTRSSKDNKFQVITGQRVFVFRTESEAQ
RDMWCSTLQSCLKEQRLLGHPRPPQPPRPLRTGMLELRGHKAKVFAALSPGELALYKSEQAFSLGIGICFIELQGCSVRETKSRSFDLLT
PHRCFSFTAESGGARQSWAAALQEAVTETLSDYEVAEKIWSNRANRQCADCGSSRPDWAAVNLGVVICKQCAGQHRALGSGISKVQSLKL
DTSVWSNEIVQLFIVLGNDRANRFWAGTLPPGEGLHPDATPGPRGEFISRKYRLGLFRKPHPQYPDHSQLLQALCAAVARPNLLKNMTQL
LCVEAFEDPSPGVYNEVVVRATYSGFLYCSPVSNKAGPSPPRRGRDAPPRLWCVLGAALEMFASENSPEPLSLIQPQDIVCLGVSPPPTD
PGDRFPFSFELILAGGRIQHFGTDGADSLEAWTSAVGKWFSPLSCHQLLGPGLLRLGRLWLRSPSHTAPAPGLWLSGFGLLRGDHLFLCS

--------------------------------------------------------------
>5773_5773_3_ARAP3-CTBP2_ARAP3_chr5_141045991_ENST00000508305_CTBP2_chr10_126678267_ENST00000411419_length(transcript)=3002nt_BP=2528nt
ACCCGCGAGCGGACGGCGGCCGCGTAGTGAGGACCTGGACATCGCTGTGTGGCTGGCCACGGTGCACCTGGAGCAGTATGCAGACACGTT
CCGACGGCATGGCCTGGCTACAGCAGGTGCAGCCCGGGGCCTGGGCCACGAGGAGTTGAAGCAGTTGGGCATCAGCGCCACAGGGCACCG
GAAACGCATTCTACGCCTGCTACAGACAGGCACCGAAGAGGGCTCCCTGGATCCCAAATCAGATAGTGCCATGGAACCATCCCCCAGCCC
AGCCCCGCAAGCCCAGCCCCCTAAGCCCGTGCCGAAGCCCAGGACCGTGTTTGGTGGACTCAGTGGCCCTGCCACCACTCAGAGACCTGG
GCTGAGCCCAGCCCTCGGGGGACCAGGAGTGTCCAGGAGCCCAGAGCCCAGCCCAAGGCCTCCTCCTCTCCCCACTTCCTCCTCTGAGCA
GTCTTCAGCCCTAAATACTGTGGAGATGATGCCTAATTCCATCTACTTCGGCCTGGACTCAAGAGGCAGGGCACAGGCAGCTCAGGACAA
GGCCCCAGACAGCTCCCAAATCTCTGCCCCCACCCCTGCCCTCAGGCCCACAACAGGCACAGTGCACATCATGGATCCTGGTTGCCTGTA
CTATGGTGTCCAACCTGTGGGGACTCCAGGAGCCCCCGACAGAAGAGAGAGCAGAGGTGTTTGTCAGGGCAGGGCTGAACACAGGCTCAG
CAGACAGGATCTGGAGGCACGGGAGGATGCTGGCTATGCCAGCCTTGAGCTACCTGGAGACTCCACCCTCTTATCGCCCACCCTGGAAAC
AGAGGAGACCAGTGATGACCTCATTTCACCCTATGCCAGCTTCTCCTTCACGGCAGACCGCCTCACGCCCCTGCTCAGTGGCTGGCTAGA
CAAGCTCTCCCCTCAGGGAAACTATGTCTTCCAGAGACGCTTTGTGCAGTTCAATGGGAGGAGTCTGATGTACTTTGGCAGTGACAAGGA
CCCCTTCCCTAAGGGTGTGATACCTTTGACTGCCATTGAGATGACCCGCAGCAGCAAGGACAACAAGTTCCAGGTCATCACCGGCCAGAG
GGTGTTCGTGTTCCGCACAGAGAGCGAGGCTCAGCGGGACATGTGGTGCTCCACGCTGCAGTCCTGTCTGAAGGAGCAGCGCCTCCTGGG
CCACCCCCGGCCCCCCCAACCACCCCGACCCCTCCGCACGGGCATGCTGGAGCTGCGTGGACACAAGGCCAAGGTGTTTGCTGCCTTGAG
CCCTGGAGAGCTGGCACTGTACAAGAGTGAGCAGGCCTTCTCTCTGGGCATCGGGATCTGCTTCATCGAACTGCAGGGCTGCAGCGTCCG
GGAGACCAAGAGTCGAAGCTTTGACCTGCTCACACCCCATCGCTGCTTCAGCTTCACAGCCGAGTCTGGGGGTGCTCGGCAGAGCTGGGC
GGCCGCTCTGCAGGAAGCAGTAACCGAGACCCTGTCTGACTACGAGGTGGCTGAGAAGATCTGGTCTAATCGGGCCAACCGGCAGTGTGC
GGACTGTGGGTCCTCCCGCCCAGATTGGGCTGCTGTCAATTTGGGGGTGGTCATCTGCAAGCAGTGTGCAGGTCAGCACCGGGCCCTGGG
TTCTGGGATCTCCAAGGTGCAGAGCCTGAAGCTGGACACGAGTGTCTGGAGTAATGAGATAGTACAGTTATTCATTGTCCTGGGAAATGA
TCGTGCCAACCGCTTCTGGGCAGGGACCCTACCCCCAGGTGAGGGACTACATCCAGATGCGACCCCTGGCCCCCGGGGAGAGTTCATCTC
CCGAAAGTACCGTCTGGGTCTCTTCCGGAAGCCCCACCCTCAGTACCCAGATCATAGCCAGCTTCTCCAGGCACTGTGTGCAGCTGTGGC
AAGACCCAACCTGCTGAAGAACATGACCCAGCTCCTCTGTGTTGAGGCCTTTGAAGACCCCTCCCCTGGTGTGTACAATGAGGTGGTGGT
GCGTGCTACTTACAGCGGCTTCCTGTACTGCAGTCCCGTCAGCAACAAAGCTGGACCCTCACCCCCTCGCAGGGGCCGGGATGCTCCCCC
GCGCCTTTGGTGTGTGCTGGGAGCAGCTCTGGAAATGTTTGCATCGGAAAACAGCCCTGAACCCCTCAGCCTCATACAGCCCCAGGATAT
TGTATGTCTGGGTGTGAGCCCCCCACCCACTGACCCAGGTGACAGGTTCCCCTTTTCCTTTGAGCTCATCCTCGCTGGGGGGAGGATCCA
GCATTTTGGCACAGATGGAGCTGACAGTCTGGAGGCCTGGACTAGTGCTGTGGGCAAGTGGTTCTCCCCGCTGAGCTGCCACCAGCTGCT
GGGCCCCGGGCTGCTGCGGCTGGGCCGCCTATGGCTGCGGTCCCCCTCCCATACAGCCCCGGCCCCTGGTCTCTGGCTGTCAGGGTTTGG
CCTCCTTCGTGGTGACCACCTCTTCCTGTGCTCAGCGCCGGGCCCAGGCCCCCCAGCCCCTGAGGACATGGTGCATCTGCGGCGGCTACA
GGAGATCAATATCCGCCAGGCATCGTGGGTGTGGCTCCAGGAGGACTTCCTGCAGCCATGGAAGGGATCATCCCTGGAGGCATCCCAGTG
ACTCACAACCTCCCGACAGTGGCACATCCTTCCCAAGCGCCCTCTCCCAACCAGCCCACAAAACACGGGGACAATCGAGAGCACCCCAAC
GAGCAATAGCAGAGAATGCCAGAAGGTAATCACTCAGATACACTTGGGACCAAGAGACAGTGAAAAATAGATGAACTAAGAGAAAAAGAA
TCGGATGGTCTTTGTAACTGATTCTGGACATATGCATCATTGATGTTGCAGTGTTGAAACTACAAGAGCTAGAAAACTGAAGATGTCGTC
TGCTTACGGAAGCGCTGAAAGACTAGGATGTGATTTATTAACGACCAACTTCTGTTATTGTGTGTTAAGTTTTTCATCTGTGCATCAAAT

>5773_5773_3_ARAP3-CTBP2_ARAP3_chr5_141045991_ENST00000508305_CTBP2_chr10_126678267_ENST00000411419_length(amino acids)=858AA_BP=832
MDIAVWLATVHLEQYADTFRRHGLATAGAARGLGHEELKQLGISATGHRKRILRLLQTGTEEGSLDPKSDSAMEPSPSPAPQAQPPKPVP
KPRTVFGGLSGPATTQRPGLSPALGGPGVSRSPEPSPRPPPLPTSSSEQSSALNTVEMMPNSIYFGLDSRGRAQAAQDKAPDSSQISAPT
PALRPTTGTVHIMDPGCLYYGVQPVGTPGAPDRRESRGVCQGRAEHRLSRQDLEAREDAGYASLELPGDSTLLSPTLETEETSDDLISPY
ASFSFTADRLTPLLSGWLDKLSPQGNYVFQRRFVQFNGRSLMYFGSDKDPFPKGVIPLTAIEMTRSSKDNKFQVITGQRVFVFRTESEAQ
RDMWCSTLQSCLKEQRLLGHPRPPQPPRPLRTGMLELRGHKAKVFAALSPGELALYKSEQAFSLGIGICFIELQGCSVRETKSRSFDLLT
PHRCFSFTAESGGARQSWAAALQEAVTETLSDYEVAEKIWSNRANRQCADCGSSRPDWAAVNLGVVICKQCAGQHRALGSGISKVQSLKL
DTSVWSNEIVQLFIVLGNDRANRFWAGTLPPGEGLHPDATPGPRGEFISRKYRLGLFRKPHPQYPDHSQLLQALCAAVARPNLLKNMTQL
LCVEAFEDPSPGVYNEVVVRATYSGFLYCSPVSNKAGPSPPRRGRDAPPRLWCVLGAALEMFASENSPEPLSLIQPQDIVCLGVSPPPTD
PGDRFPFSFELILAGGRIQHFGTDGADSLEAWTSAVGKWFSPLSCHQLLGPGLLRLGRLWLRSPSHTAPAPGLWLSGFGLLRGDHLFLCS

--------------------------------------------------------------
>5773_5773_4_ARAP3-CTBP2_ARAP3_chr5_141045991_ENST00000508305_CTBP2_chr10_126678267_ENST00000531469_length(transcript)=3002nt_BP=2528nt
ACCCGCGAGCGGACGGCGGCCGCGTAGTGAGGACCTGGACATCGCTGTGTGGCTGGCCACGGTGCACCTGGAGCAGTATGCAGACACGTT
CCGACGGCATGGCCTGGCTACAGCAGGTGCAGCCCGGGGCCTGGGCCACGAGGAGTTGAAGCAGTTGGGCATCAGCGCCACAGGGCACCG
GAAACGCATTCTACGCCTGCTACAGACAGGCACCGAAGAGGGCTCCCTGGATCCCAAATCAGATAGTGCCATGGAACCATCCCCCAGCCC
AGCCCCGCAAGCCCAGCCCCCTAAGCCCGTGCCGAAGCCCAGGACCGTGTTTGGTGGACTCAGTGGCCCTGCCACCACTCAGAGACCTGG
GCTGAGCCCAGCCCTCGGGGGACCAGGAGTGTCCAGGAGCCCAGAGCCCAGCCCAAGGCCTCCTCCTCTCCCCACTTCCTCCTCTGAGCA
GTCTTCAGCCCTAAATACTGTGGAGATGATGCCTAATTCCATCTACTTCGGCCTGGACTCAAGAGGCAGGGCACAGGCAGCTCAGGACAA
GGCCCCAGACAGCTCCCAAATCTCTGCCCCCACCCCTGCCCTCAGGCCCACAACAGGCACAGTGCACATCATGGATCCTGGTTGCCTGTA
CTATGGTGTCCAACCTGTGGGGACTCCAGGAGCCCCCGACAGAAGAGAGAGCAGAGGTGTTTGTCAGGGCAGGGCTGAACACAGGCTCAG
CAGACAGGATCTGGAGGCACGGGAGGATGCTGGCTATGCCAGCCTTGAGCTACCTGGAGACTCCACCCTCTTATCGCCCACCCTGGAAAC
AGAGGAGACCAGTGATGACCTCATTTCACCCTATGCCAGCTTCTCCTTCACGGCAGACCGCCTCACGCCCCTGCTCAGTGGCTGGCTAGA
CAAGCTCTCCCCTCAGGGAAACTATGTCTTCCAGAGACGCTTTGTGCAGTTCAATGGGAGGAGTCTGATGTACTTTGGCAGTGACAAGGA
CCCCTTCCCTAAGGGTGTGATACCTTTGACTGCCATTGAGATGACCCGCAGCAGCAAGGACAACAAGTTCCAGGTCATCACCGGCCAGAG
GGTGTTCGTGTTCCGCACAGAGAGCGAGGCTCAGCGGGACATGTGGTGCTCCACGCTGCAGTCCTGTCTGAAGGAGCAGCGCCTCCTGGG
CCACCCCCGGCCCCCCCAACCACCCCGACCCCTCCGCACGGGCATGCTGGAGCTGCGTGGACACAAGGCCAAGGTGTTTGCTGCCTTGAG
CCCTGGAGAGCTGGCACTGTACAAGAGTGAGCAGGCCTTCTCTCTGGGCATCGGGATCTGCTTCATCGAACTGCAGGGCTGCAGCGTCCG
GGAGACCAAGAGTCGAAGCTTTGACCTGCTCACACCCCATCGCTGCTTCAGCTTCACAGCCGAGTCTGGGGGTGCTCGGCAGAGCTGGGC
GGCCGCTCTGCAGGAAGCAGTAACCGAGACCCTGTCTGACTACGAGGTGGCTGAGAAGATCTGGTCTAATCGGGCCAACCGGCAGTGTGC
GGACTGTGGGTCCTCCCGCCCAGATTGGGCTGCTGTCAATTTGGGGGTGGTCATCTGCAAGCAGTGTGCAGGTCAGCACCGGGCCCTGGG
TTCTGGGATCTCCAAGGTGCAGAGCCTGAAGCTGGACACGAGTGTCTGGAGTAATGAGATAGTACAGTTATTCATTGTCCTGGGAAATGA
TCGTGCCAACCGCTTCTGGGCAGGGACCCTACCCCCAGGTGAGGGACTACATCCAGATGCGACCCCTGGCCCCCGGGGAGAGTTCATCTC
CCGAAAGTACCGTCTGGGTCTCTTCCGGAAGCCCCACCCTCAGTACCCAGATCATAGCCAGCTTCTCCAGGCACTGTGTGCAGCTGTGGC
AAGACCCAACCTGCTGAAGAACATGACCCAGCTCCTCTGTGTTGAGGCCTTTGAAGACCCCTCCCCTGGTGTGTACAATGAGGTGGTGGT
GCGTGCTACTTACAGCGGCTTCCTGTACTGCAGTCCCGTCAGCAACAAAGCTGGACCCTCACCCCCTCGCAGGGGCCGGGATGCTCCCCC
GCGCCTTTGGTGTGTGCTGGGAGCAGCTCTGGAAATGTTTGCATCGGAAAACAGCCCTGAACCCCTCAGCCTCATACAGCCCCAGGATAT
TGTATGTCTGGGTGTGAGCCCCCCACCCACTGACCCAGGTGACAGGTTCCCCTTTTCCTTTGAGCTCATCCTCGCTGGGGGGAGGATCCA
GCATTTTGGCACAGATGGAGCTGACAGTCTGGAGGCCTGGACTAGTGCTGTGGGCAAGTGGTTCTCCCCGCTGAGCTGCCACCAGCTGCT
GGGCCCCGGGCTGCTGCGGCTGGGCCGCCTATGGCTGCGGTCCCCCTCCCATACAGCCCCGGCCCCTGGTCTCTGGCTGTCAGGGTTTGG
CCTCCTTCGTGGTGACCACCTCTTCCTGTGCTCAGCGCCGGGCCCAGGCCCCCCAGCCCCTGAGGACATGGTGCATCTGCGGCGGCTACA
GGAGATCAATATCCGCCAGGCATCGTGGGTGTGGCTCCAGGAGGACTTCCTGCAGCCATGGAAGGGATCATCCCTGGAGGCATCCCAGTG
ACTCACAACCTCCCGACAGTGGCACATCCTTCCCAAGCGCCCTCTCCCAACCAGCCCACAAAACACGGGGACAATCGAGAGCACCCCAAC
GAGCAATAGCAGAGAATGCCAGAAGGTAATCACTCAGATACACTTGGGACCAAGAGACAGTGAAAAATAGATGAACTAAGAGAAAAAGAA
TCGGATGGTCTTTGTAACTGATTCTGGACATATGCATCATTGATGTTGCAGTGTTGAAACTACAAGAGCTAGAAAACTGAAGATGTCGTC
TGCTTACGGAAGCGCTGAAAGACTAGGATGTGATTTATTAACGACCAACTTCTGTTATTGTGTGTTAAGTTTTTCATCTGTGCATCAAAT

>5773_5773_4_ARAP3-CTBP2_ARAP3_chr5_141045991_ENST00000508305_CTBP2_chr10_126678267_ENST00000531469_length(amino acids)=858AA_BP=832
MDIAVWLATVHLEQYADTFRRHGLATAGAARGLGHEELKQLGISATGHRKRILRLLQTGTEEGSLDPKSDSAMEPSPSPAPQAQPPKPVP
KPRTVFGGLSGPATTQRPGLSPALGGPGVSRSPEPSPRPPPLPTSSSEQSSALNTVEMMPNSIYFGLDSRGRAQAAQDKAPDSSQISAPT
PALRPTTGTVHIMDPGCLYYGVQPVGTPGAPDRRESRGVCQGRAEHRLSRQDLEAREDAGYASLELPGDSTLLSPTLETEETSDDLISPY
ASFSFTADRLTPLLSGWLDKLSPQGNYVFQRRFVQFNGRSLMYFGSDKDPFPKGVIPLTAIEMTRSSKDNKFQVITGQRVFVFRTESEAQ
RDMWCSTLQSCLKEQRLLGHPRPPQPPRPLRTGMLELRGHKAKVFAALSPGELALYKSEQAFSLGIGICFIELQGCSVRETKSRSFDLLT
PHRCFSFTAESGGARQSWAAALQEAVTETLSDYEVAEKIWSNRANRQCADCGSSRPDWAAVNLGVVICKQCAGQHRALGSGISKVQSLKL
DTSVWSNEIVQLFIVLGNDRANRFWAGTLPPGEGLHPDATPGPRGEFISRKYRLGLFRKPHPQYPDHSQLLQALCAAVARPNLLKNMTQL
LCVEAFEDPSPGVYNEVVVRATYSGFLYCSPVSNKAGPSPPRRGRDAPPRLWCVLGAALEMFASENSPEPLSLIQPQDIVCLGVSPPPTD
PGDRFPFSFELILAGGRIQHFGTDGADSLEAWTSAVGKWFSPLSCHQLLGPGLLRLGRLWLRSPSHTAPAPGLWLSGFGLLRGDHLFLCS

--------------------------------------------------------------
>5773_5773_5_ARAP3-CTBP2_ARAP3_chr5_141045991_ENST00000513878_CTBP2_chr10_126678267_ENST00000337195_length(transcript)=3474nt_BP=1627nt
ATGGGTCATTGAGCTCTCTCTCTCCAGGACCCCTTCCCTAAGGGTGTGATACCTTTGACTGCCATTGAGATGACCCGCAGCAGCAAGGAC
AACAAGTTCCAGGTCATCACCGGCCAGAGGGTGTTCGTGTTCCGCACAGAGAGCGAGGCTCAGCGGGACATGTGGTGCTCCACGCTGCAG
TCCTGTCTGAAGGAGCAGCGCCTCCTGGGCCACCCCCGGCCCCCCCAACCACCCCGACCCCTCCGCACGGGCATGCTGGAGCTGCGTGGA
CACAAGGCCAAGGTGTTTGCTGCCTTGAGCCCTGGAGAGCTGGCACTGTACAAGAGTGAGCAGGCCTTCTCTCTGGGCATCGGGATCTGC
TTCATCGAACTGCAGGGCTGCAGCGTCCGGGAGACCAAGAGTCGAAGCTTTGACCTGCTCACACCCCATCGCTGCTTCAGCTTCACAGCC
GAGTCTGGGGGTGCTCGGCAGAGCTGGGCGGCCGCTCTGCAGGAAGCAGTAACCGAGACCCTGTCTGACTACGAGGTGGCTGAGAAGATC
TGGTCTAATCGGGCCAACCGGCAGTGTGCGGACTGTGGGTCCTCCCGCCCAGATTGGGCTGCTGTCAATTTGGGGGTGGTCATCTGCAAG
CAGTGTGCAGGTCAGCACCGGGCCCTGGGTTCTGGGATCTCCAAGGTGCAGAGCCTGAAGCTGGACACGAGTGTCTGGAGTAATGAGATA
GTACAGTTATTCATTGTCCTGGGAAATGATCGTGCCAACCGCTTCTGGGCAGGGACCCTACCCCCAGGTGAGGGACTACATCCAGATGCG
ACCCCTGGCCCCCGGGGAGAGTTCATCTCCCGAAAGTACCGTCTGGGTCTCTTCCGGAAGCCCCACCCTCAGTACCCAGATCATAGCCAG
CTTCTCCAGGCACTGTGTGCAGCTGTGGCAAGACCCAACCTGCTGAAGAACATGACCCAGCTCCTCTGTGTTGAGGCCTTTGAAGGCGAG
GAGCCCTGGTTCCCCCCAGCCCCTGATGGCAGCTGCCCTGGCCTCTTGCCCTCAGACCCCTCCCCTGGTGTGTACAATGAGGTGGTGGTG
CGTGCTACTTACAGCGGCTTCCTGTACTGCAGTCCCGTCAGCAACAAAGCTGGACCCTCACCCCCTCGCAGGGGCCGGGATGCTCCCCCG
CGCCTTTGGTGTGTGCTGGGAGCAGCTCTGGAAATGTTTGCATCGGAAAACAGCCCTGAACCCCTCAGCCTCATACAGCCCCAGGATATT
GTATGTCTGGGTGTGAGCCCCCCACCCACTGACCCAGGTGACAGGTTCCCCTTTTCCTTTGAGCTCATCCTCGCTGGGGGGAGGATCCAG
CATTTTGGCACAGATGGAGCTGACAGTCTGGAGGCCTGGACTAGTGCTGTGGGCAAGTGGTTCTCCCCGCTGAGCTGCCACCAGCTGCTG
GGCCCCGGGCTGCTGCGGCTGGGCCGCCTATGGCTGCGGTCCCCCTCCCATACAGCCCCGGCCCCTGGTCTCTGGCTGTCAGGGTTTGGC
CTCCTTCGTGGTGACCACCTCTTCCTGTGCTCAGCGCCGGGCCCAGGCCCCCCAGCCCCTGAGGACATGGTGCATCTGCGGCGGCTACAG
GAGATCAATATCCGCCAGGCATCGTGGGTGTGGCTCCAGGAGGACTTCCTGCAGCCATGGAAGGGATCATCCCTGGAGGCATCCCAGTGA
CTCACAACCTCCCGACAGTGGCACATCCTTCCCAAGCGCCCTCTCCCAACCAGCCCACAAAACACGGGGACAATCGAGAGCACCCCAACG
AGCAATAGCAGAGAATGCCAGAAGGTAATCACTCAGATACACTTGGGACCAAGAGACAGTGAAAAATAGATGAACTAAGAGAAAAAGAAT
CGGATGGTCTTTGTAACTGATTCTGGACATATGCATCATTGATGTTGCAGTGTTGAAACTACAAGAGCTAGAAAACTGAAGATGTCGTCT
GCTTACGGAAGCGCTGAAAGACTAGGATGTGATTTATTAACGACCAACTTCTGTTATTGTGTGTTAAGTTTTTCATCTGTGCATCAAATC
ACAAAAAGAATAAATAGAGCTTTTTCCTTTATCAGTCCCTTGGGCACAGCAGGTCCTGAACACCCTGCTCTACAATGTTGCATCAAGAGT
TCAAACAACAAAATAAAAAATATTAAGAGGAAATCCCCATCCTGTGACTTGAGTCCCTTAAGTCTACAGGGGCTGGTGACCTCTTTTTGC
TAATAGGAAAATCACATTACTACAAAATGGGGAGAAAACTGTTTGCCTGTGGTAGACACCTGCACGCATAGGATTGAAGACAGTACAGGC
TGCTGTACAGAGAAGCGCCTCTCACATCTGAACTGCATACTGAGCGGGCAAGTCGGTTGTAAGTTCAGTAAAACCCTCTGATGATGCAAA
AAAAAAAAAAAAAGTATTAAGTTTCACAAGCTGTTTGTACTCAAATATATTTTCTCAGTTTCAGATCCTCTGCTATTTTATTGAGTGGAA
AGTCTTGAGCTAAAAGGGTTCAAGAAGAATAATGTTGCATTTCCTTATGTCTCAGGAAACACTTTTTATGGTAACTTGTCAGATTGTCTA
TGAACAAACCCACTTTTTTAGACATTGATAAAGTCTTCTTTTCTTCACGTGATATTTTATACAAGAACACTTCAGATGTATTAGATGTGA
CTGATTTTAACAAATCCTATTAGATTTGTATCAACTAGTTACATGTTCTATTCATAGTCTTTTGTGAATCATTGCCTTTTTGTTTAAAAA
GATGGCCTATTTTGAGCCTTTGTATAGGTACATTCCTGTTTTTGTGACAAAAGAAAAACTTTAAAATTGTCCCAAACAGAAAAATAATGG
CTATCAGAAGTATGTTTTGTTTTAGTGTGAGTTACCGTTACTGTATTTGTTTATTGTAAAGGTGGACATTTAGCGTTCAGTGCAGTTTTC
AATAAAAAGTAATTAAAATTTGTTAAGTTCTGAAATTCAAGTACATCTCACTAATGTAAATGTTCTCTACTTGAGATGTTTAAGGCAATT
GCATTGTCAATTAGCCAATTTCCAGCTCTTGTTACTACAGGGTTCCATAACCAGACTCAAGACCGCTGACAATTAATTACCTGTGATAAC
AAAAAGTTTAATTGAAAAATCAAAACCTCACACAAGTCCATCATTATCACGTCATGCCATCCTTAAGATGCAATGGTGGGTTAGTGCTAA
ATCAATTCAAAAAAAAACAAAGTTGCTCAACTTTTAGAGTTCTGACTTTAATCTACCCCAAAGCAAAATGACCTGGACCTGGTTCAAGGG
AGGGAAGTGAACCTTGAAACTGTTTTGCCAATAACCTAACAAACAAAATGATATTTACAAAGAAGTGTTGCAAATAGTCCCATGAGTTAA

>5773_5773_5_ARAP3-CTBP2_ARAP3_chr5_141045991_ENST00000513878_CTBP2_chr10_126678267_ENST00000337195_length(amino acids)=551AA_BP=525
MTAIEMTRSSKDNKFQVITGQRVFVFRTESEAQRDMWCSTLQSCLKEQRLLGHPRPPQPPRPLRTGMLELRGHKAKVFAALSPGELALYK
SEQAFSLGIGICFIELQGCSVRETKSRSFDLLTPHRCFSFTAESGGARQSWAAALQEAVTETLSDYEVAEKIWSNRANRQCADCGSSRPD
WAAVNLGVVICKQCAGQHRALGSGISKVQSLKLDTSVWSNEIVQLFIVLGNDRANRFWAGTLPPGEGLHPDATPGPRGEFISRKYRLGLF
RKPHPQYPDHSQLLQALCAAVARPNLLKNMTQLLCVEAFEGEEPWFPPAPDGSCPGLLPSDPSPGVYNEVVVRATYSGFLYCSPVSNKAG
PSPPRRGRDAPPRLWCVLGAALEMFASENSPEPLSLIQPQDIVCLGVSPPPTDPGDRFPFSFELILAGGRIQHFGTDGADSLEAWTSAVG
KWFSPLSCHQLLGPGLLRLGRLWLRSPSHTAPAPGLWLSGFGLLRGDHLFLCSAPGPGPPAPEDMVHLRRLQEINIRQASWVWLQEDFLQ

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>5773_5773_6_ARAP3-CTBP2_ARAP3_chr5_141045991_ENST00000513878_CTBP2_chr10_126678267_ENST00000411419_length(transcript)=2101nt_BP=1627nt
ATGGGTCATTGAGCTCTCTCTCTCCAGGACCCCTTCCCTAAGGGTGTGATACCTTTGACTGCCATTGAGATGACCCGCAGCAGCAAGGAC
AACAAGTTCCAGGTCATCACCGGCCAGAGGGTGTTCGTGTTCCGCACAGAGAGCGAGGCTCAGCGGGACATGTGGTGCTCCACGCTGCAG
TCCTGTCTGAAGGAGCAGCGCCTCCTGGGCCACCCCCGGCCCCCCCAACCACCCCGACCCCTCCGCACGGGCATGCTGGAGCTGCGTGGA
CACAAGGCCAAGGTGTTTGCTGCCTTGAGCCCTGGAGAGCTGGCACTGTACAAGAGTGAGCAGGCCTTCTCTCTGGGCATCGGGATCTGC
TTCATCGAACTGCAGGGCTGCAGCGTCCGGGAGACCAAGAGTCGAAGCTTTGACCTGCTCACACCCCATCGCTGCTTCAGCTTCACAGCC
GAGTCTGGGGGTGCTCGGCAGAGCTGGGCGGCCGCTCTGCAGGAAGCAGTAACCGAGACCCTGTCTGACTACGAGGTGGCTGAGAAGATC
TGGTCTAATCGGGCCAACCGGCAGTGTGCGGACTGTGGGTCCTCCCGCCCAGATTGGGCTGCTGTCAATTTGGGGGTGGTCATCTGCAAG
CAGTGTGCAGGTCAGCACCGGGCCCTGGGTTCTGGGATCTCCAAGGTGCAGAGCCTGAAGCTGGACACGAGTGTCTGGAGTAATGAGATA
GTACAGTTATTCATTGTCCTGGGAAATGATCGTGCCAACCGCTTCTGGGCAGGGACCCTACCCCCAGGTGAGGGACTACATCCAGATGCG
ACCCCTGGCCCCCGGGGAGAGTTCATCTCCCGAAAGTACCGTCTGGGTCTCTTCCGGAAGCCCCACCCTCAGTACCCAGATCATAGCCAG
CTTCTCCAGGCACTGTGTGCAGCTGTGGCAAGACCCAACCTGCTGAAGAACATGACCCAGCTCCTCTGTGTTGAGGCCTTTGAAGGCGAG
GAGCCCTGGTTCCCCCCAGCCCCTGATGGCAGCTGCCCTGGCCTCTTGCCCTCAGACCCCTCCCCTGGTGTGTACAATGAGGTGGTGGTG
CGTGCTACTTACAGCGGCTTCCTGTACTGCAGTCCCGTCAGCAACAAAGCTGGACCCTCACCCCCTCGCAGGGGCCGGGATGCTCCCCCG
CGCCTTTGGTGTGTGCTGGGAGCAGCTCTGGAAATGTTTGCATCGGAAAACAGCCCTGAACCCCTCAGCCTCATACAGCCCCAGGATATT
GTATGTCTGGGTGTGAGCCCCCCACCCACTGACCCAGGTGACAGGTTCCCCTTTTCCTTTGAGCTCATCCTCGCTGGGGGGAGGATCCAG
CATTTTGGCACAGATGGAGCTGACAGTCTGGAGGCCTGGACTAGTGCTGTGGGCAAGTGGTTCTCCCCGCTGAGCTGCCACCAGCTGCTG
GGCCCCGGGCTGCTGCGGCTGGGCCGCCTATGGCTGCGGTCCCCCTCCCATACAGCCCCGGCCCCTGGTCTCTGGCTGTCAGGGTTTGGC
CTCCTTCGTGGTGACCACCTCTTCCTGTGCTCAGCGCCGGGCCCAGGCCCCCCAGCCCCTGAGGACATGGTGCATCTGCGGCGGCTACAG
GAGATCAATATCCGCCAGGCATCGTGGGTGTGGCTCCAGGAGGACTTCCTGCAGCCATGGAAGGGATCATCCCTGGAGGCATCCCAGTGA
CTCACAACCTCCCGACAGTGGCACATCCTTCCCAAGCGCCCTCTCCCAACCAGCCCACAAAACACGGGGACAATCGAGAGCACCCCAACG
AGCAATAGCAGAGAATGCCAGAAGGTAATCACTCAGATACACTTGGGACCAAGAGACAGTGAAAAATAGATGAACTAAGAGAAAAAGAAT
CGGATGGTCTTTGTAACTGATTCTGGACATATGCATCATTGATGTTGCAGTGTTGAAACTACAAGAGCTAGAAAACTGAAGATGTCGTCT
GCTTACGGAAGCGCTGAAAGACTAGGATGTGATTTATTAACGACCAACTTCTGTTATTGTGTGTTAAGTTTTTCATCTGTGCATCAAATC

>5773_5773_6_ARAP3-CTBP2_ARAP3_chr5_141045991_ENST00000513878_CTBP2_chr10_126678267_ENST00000411419_length(amino acids)=551AA_BP=525
MTAIEMTRSSKDNKFQVITGQRVFVFRTESEAQRDMWCSTLQSCLKEQRLLGHPRPPQPPRPLRTGMLELRGHKAKVFAALSPGELALYK
SEQAFSLGIGICFIELQGCSVRETKSRSFDLLTPHRCFSFTAESGGARQSWAAALQEAVTETLSDYEVAEKIWSNRANRQCADCGSSRPD
WAAVNLGVVICKQCAGQHRALGSGISKVQSLKLDTSVWSNEIVQLFIVLGNDRANRFWAGTLPPGEGLHPDATPGPRGEFISRKYRLGLF
RKPHPQYPDHSQLLQALCAAVARPNLLKNMTQLLCVEAFEGEEPWFPPAPDGSCPGLLPSDPSPGVYNEVVVRATYSGFLYCSPVSNKAG
PSPPRRGRDAPPRLWCVLGAALEMFASENSPEPLSLIQPQDIVCLGVSPPPTDPGDRFPFSFELILAGGRIQHFGTDGADSLEAWTSAVG
KWFSPLSCHQLLGPGLLRLGRLWLRSPSHTAPAPGLWLSGFGLLRGDHLFLCSAPGPGPPAPEDMVHLRRLQEINIRQASWVWLQEDFLQ

--------------------------------------------------------------
>5773_5773_7_ARAP3-CTBP2_ARAP3_chr5_141045991_ENST00000513878_CTBP2_chr10_126678267_ENST00000531469_length(transcript)=2101nt_BP=1627nt
ATGGGTCATTGAGCTCTCTCTCTCCAGGACCCCTTCCCTAAGGGTGTGATACCTTTGACTGCCATTGAGATGACCCGCAGCAGCAAGGAC
AACAAGTTCCAGGTCATCACCGGCCAGAGGGTGTTCGTGTTCCGCACAGAGAGCGAGGCTCAGCGGGACATGTGGTGCTCCACGCTGCAG
TCCTGTCTGAAGGAGCAGCGCCTCCTGGGCCACCCCCGGCCCCCCCAACCACCCCGACCCCTCCGCACGGGCATGCTGGAGCTGCGTGGA
CACAAGGCCAAGGTGTTTGCTGCCTTGAGCCCTGGAGAGCTGGCACTGTACAAGAGTGAGCAGGCCTTCTCTCTGGGCATCGGGATCTGC
TTCATCGAACTGCAGGGCTGCAGCGTCCGGGAGACCAAGAGTCGAAGCTTTGACCTGCTCACACCCCATCGCTGCTTCAGCTTCACAGCC
GAGTCTGGGGGTGCTCGGCAGAGCTGGGCGGCCGCTCTGCAGGAAGCAGTAACCGAGACCCTGTCTGACTACGAGGTGGCTGAGAAGATC
TGGTCTAATCGGGCCAACCGGCAGTGTGCGGACTGTGGGTCCTCCCGCCCAGATTGGGCTGCTGTCAATTTGGGGGTGGTCATCTGCAAG
CAGTGTGCAGGTCAGCACCGGGCCCTGGGTTCTGGGATCTCCAAGGTGCAGAGCCTGAAGCTGGACACGAGTGTCTGGAGTAATGAGATA
GTACAGTTATTCATTGTCCTGGGAAATGATCGTGCCAACCGCTTCTGGGCAGGGACCCTACCCCCAGGTGAGGGACTACATCCAGATGCG
ACCCCTGGCCCCCGGGGAGAGTTCATCTCCCGAAAGTACCGTCTGGGTCTCTTCCGGAAGCCCCACCCTCAGTACCCAGATCATAGCCAG
CTTCTCCAGGCACTGTGTGCAGCTGTGGCAAGACCCAACCTGCTGAAGAACATGACCCAGCTCCTCTGTGTTGAGGCCTTTGAAGGCGAG
GAGCCCTGGTTCCCCCCAGCCCCTGATGGCAGCTGCCCTGGCCTCTTGCCCTCAGACCCCTCCCCTGGTGTGTACAATGAGGTGGTGGTG
CGTGCTACTTACAGCGGCTTCCTGTACTGCAGTCCCGTCAGCAACAAAGCTGGACCCTCACCCCCTCGCAGGGGCCGGGATGCTCCCCCG
CGCCTTTGGTGTGTGCTGGGAGCAGCTCTGGAAATGTTTGCATCGGAAAACAGCCCTGAACCCCTCAGCCTCATACAGCCCCAGGATATT
GTATGTCTGGGTGTGAGCCCCCCACCCACTGACCCAGGTGACAGGTTCCCCTTTTCCTTTGAGCTCATCCTCGCTGGGGGGAGGATCCAG
CATTTTGGCACAGATGGAGCTGACAGTCTGGAGGCCTGGACTAGTGCTGTGGGCAAGTGGTTCTCCCCGCTGAGCTGCCACCAGCTGCTG
GGCCCCGGGCTGCTGCGGCTGGGCCGCCTATGGCTGCGGTCCCCCTCCCATACAGCCCCGGCCCCTGGTCTCTGGCTGTCAGGGTTTGGC
CTCCTTCGTGGTGACCACCTCTTCCTGTGCTCAGCGCCGGGCCCAGGCCCCCCAGCCCCTGAGGACATGGTGCATCTGCGGCGGCTACAG
GAGATCAATATCCGCCAGGCATCGTGGGTGTGGCTCCAGGAGGACTTCCTGCAGCCATGGAAGGGATCATCCCTGGAGGCATCCCAGTGA
CTCACAACCTCCCGACAGTGGCACATCCTTCCCAAGCGCCCTCTCCCAACCAGCCCACAAAACACGGGGACAATCGAGAGCACCCCAACG
AGCAATAGCAGAGAATGCCAGAAGGTAATCACTCAGATACACTTGGGACCAAGAGACAGTGAAAAATAGATGAACTAAGAGAAAAAGAAT
CGGATGGTCTTTGTAACTGATTCTGGACATATGCATCATTGATGTTGCAGTGTTGAAACTACAAGAGCTAGAAAACTGAAGATGTCGTCT
GCTTACGGAAGCGCTGAAAGACTAGGATGTGATTTATTAACGACCAACTTCTGTTATTGTGTGTTAAGTTTTTCATCTGTGCATCAAATC

>5773_5773_7_ARAP3-CTBP2_ARAP3_chr5_141045991_ENST00000513878_CTBP2_chr10_126678267_ENST00000531469_length(amino acids)=551AA_BP=525
MTAIEMTRSSKDNKFQVITGQRVFVFRTESEAQRDMWCSTLQSCLKEQRLLGHPRPPQPPRPLRTGMLELRGHKAKVFAALSPGELALYK
SEQAFSLGIGICFIELQGCSVRETKSRSFDLLTPHRCFSFTAESGGARQSWAAALQEAVTETLSDYEVAEKIWSNRANRQCADCGSSRPD
WAAVNLGVVICKQCAGQHRALGSGISKVQSLKLDTSVWSNEIVQLFIVLGNDRANRFWAGTLPPGEGLHPDATPGPRGEFISRKYRLGLF
RKPHPQYPDHSQLLQALCAAVARPNLLKNMTQLLCVEAFEGEEPWFPPAPDGSCPGLLPSDPSPGVYNEVVVRATYSGFLYCSPVSNKAG
PSPPRRGRDAPPRLWCVLGAALEMFASENSPEPLSLIQPQDIVCLGVSPPPTDPGDRFPFSFELILAGGRIQHFGTDGADSLEAWTSAVG
KWFSPLSCHQLLGPGLLRLGRLWLRSPSHTAPAPGLWLSGFGLLRGDHLFLCSAPGPGPPAPEDMVHLRRLQEINIRQASWVWLQEDFLQ

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ARAP3-CTBP2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ARAP3-CTBP2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ARAP3-CTBP2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneARAP3C0019693HIV Infections1CTD_human
HgeneARAP3C4505456HIV Coinfection1CTD_human
TgeneC0007621Neoplastic Cell Transformation1CTD_human
TgeneC0027626Neoplasm Invasiveness1CTD_human
TgeneC0033578Prostatic Neoplasms1CTD_human
TgeneC0376358Malignant neoplasm of prostate1CTD_human