Fusion Gene Studies
in Kim Lab

FusionBase FusionGDB FusionGDB2 FusionPDB FusionNeoAntigen FusionAI FusionNW FGviewer Publication Contact
FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:C6orf106-PRKCB (FusionGDB2 ID:HG64771TG5579)

Fusion Gene Summary for C6orf106-PRKCB

check button Fusion gene summary
Fusion gene informationFusion gene name: C6orf106-PRKCB
Fusion gene ID: hg64771tg5579
HgeneTgene
Gene symbol

C6orf106

PRKCB

Gene ID

64771

5579

Gene nameinflammation and lipid regulator with UBA-like and NBR1-like domainsprotein kinase C beta
SynonymsC6orf106|FP852|dJ391O22.4PKC-beta|PKCB|PKCI(2)|PKCbeta|PRKCB1|PRKCB2
Cytomap('C6orf106')('PRKCB')

6p21.31

16p12.2-p12.1

Type of geneprotein-codingprotein-coding
Descriptionprotein ILRUNinflammation and lipid regulator with UBA-like and NBR1-like domains proteinuncharacterized protein C6orf106protein kinase C beta typePKC-Bprotein kinase C, beta 1 polypeptide
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000374021, ENST00000374023, 
ENST00000374026, 
Fusion gene scores* DoF score16 X 9 X 9=129620 X 15 X 13=3900
# samples 2125
** MAII scorelog2(21/1296*10)=-2.6256044852185
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(25/3900*10)=-3.96347412397489
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: C6orf106 [Title/Abstract] AND PRKCB [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointC6orf106(34574331)-PRKCB(24043456), # samples:1
Anticipated loss of major functional domain due to fusion event.C6orf106-PRKCB seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
C6orf106-PRKCB seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
C6orf106-PRKCB seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
C6orf106-PRKCB seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
C6orf106-PRKCB seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
C6orf106-PRKCB seems lost the major protein functional domain in Tgene partner, which is a epigenetic factor due to the frame-shifted ORF.
C6orf106-PRKCB seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
C6orf106-PRKCB seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
C6orf106-PRKCB seems lost the major protein functional domain in Tgene partner, which is a kinase due to the frame-shifted ORF.
C6orf106-PRKCB seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneC6orf106

GO:0043392

negative regulation of DNA binding

29802199

TgenePRKCB

GO:0010827

regulation of glucose transmembrane transport

25982116

TgenePRKCB

GO:0035408

histone H3-T6 phosphorylation

20228790


check buttonFusion gene breakpoints across C6orf106 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across PRKCB (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4Non-Cancer61NC6orf106chr6

34574331

-PRKCBchr16

24043456

+


Top

Fusion Gene ORF analysis for C6orf106-PRKCB

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000374021ENST00000482000C6orf106chr6

34574331

-PRKCBchr16

24043456

+
5CDS-intronENST00000374021ENST00000498058C6orf106chr6

34574331

-PRKCBchr16

24043456

+
5CDS-intronENST00000374023ENST00000482000C6orf106chr6

34574331

-PRKCBchr16

24043456

+
5CDS-intronENST00000374023ENST00000498058C6orf106chr6

34574331

-PRKCBchr16

24043456

+
5CDS-intronENST00000374026ENST00000482000C6orf106chr6

34574331

-PRKCBchr16

24043456

+
5CDS-intronENST00000374026ENST00000498058C6orf106chr6

34574331

-PRKCBchr16

24043456

+
Frame-shiftENST00000374021ENST00000303531C6orf106chr6

34574331

-PRKCBchr16

24043456

+
Frame-shiftENST00000374021ENST00000321728C6orf106chr6

34574331

-PRKCBchr16

24043456

+
In-frameENST00000374023ENST00000303531C6orf106chr6

34574331

-PRKCBchr16

24043456

+
In-frameENST00000374023ENST00000321728C6orf106chr6

34574331

-PRKCBchr16

24043456

+
In-frameENST00000374026ENST00000303531C6orf106chr6

34574331

-PRKCBchr16

24043456

+
In-frameENST00000374026ENST00000321728C6orf106chr6

34574331

-PRKCBchr16

24043456

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000374023C6orf106chr634574331-ENST00000321728PRKCBchr1624043456+333111052022832876
ENST00000374023C6orf106chr634574331-ENST00000303531PRKCBchr1624043456+863411052022838878
ENST00000374026C6orf106chr634574331-ENST00000321728PRKCBchr1624043456+31459192142646810
ENST00000374026C6orf106chr634574331-ENST00000303531PRKCBchr1624043456+84489192142652812

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000374023ENST00000321728C6orf106chr634574331-PRKCBchr1624043456+0.0010722840.99892765
ENST00000374023ENST00000303531C6orf106chr634574331-PRKCBchr1624043456+0.0005027190.9994973
ENST00000374026ENST00000321728C6orf106chr634574331-PRKCBchr1624043456+0.001587360.9984126
ENST00000374026ENST00000303531C6orf106chr634574331-PRKCBchr1624043456+0.0007089830.99929094

Top

Fusion Genomic Features for C6orf106-PRKCB


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
C6orf106chr634574331-PRKCBchr1624043456+0.848292350.1517076
C6orf106chr634574331-PRKCBchr1624043456+0.848292350.1517076

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for C6orf106-PRKCB


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr6:34574331/chr16:24043456)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgenePRKCBchr6:34574331chr16:24043456ENST00000303531217158_27596674.0DomainC2
TgenePRKCBchr6:34574331chr16:24043456ENST00000303531217342_60096674.0DomainProtein kinase
TgenePRKCBchr6:34574331chr16:24043456ENST00000303531217601_67196674.0DomainAGC-kinase C-terminal
TgenePRKCBchr6:34574331chr16:24043456ENST00000321728217158_27596672.0DomainC2
TgenePRKCBchr6:34574331chr16:24043456ENST00000321728217342_60096672.0DomainProtein kinase
TgenePRKCBchr6:34574331chr16:24043456ENST00000321728217601_67196672.0DomainAGC-kinase C-terminal
TgenePRKCBchr6:34574331chr16:24043456ENST0000049805802158_275058.0DomainC2
TgenePRKCBchr6:34574331chr16:24043456ENST0000049805802342_600058.0DomainProtein kinase
TgenePRKCBchr6:34574331chr16:24043456ENST0000049805802601_671058.0DomainAGC-kinase C-terminal
TgenePRKCBchr6:34574331chr16:24043456ENST00000303531217348_35696674.0Nucleotide bindingATP
TgenePRKCBchr6:34574331chr16:24043456ENST00000321728217348_35696672.0Nucleotide bindingATP
TgenePRKCBchr6:34574331chr16:24043456ENST0000049805802348_356058.0Nucleotide bindingATP
TgenePRKCBchr6:34574331chr16:24043456ENST00000303531217101_15196674.0Zinc fingerPhorbol-ester/DAG-type 2
TgenePRKCBchr6:34574331chr16:24043456ENST00000321728217101_15196672.0Zinc fingerPhorbol-ester/DAG-type 2
TgenePRKCBchr6:34574331chr16:24043456ENST0000049805802101_151058.0Zinc fingerPhorbol-ester/DAG-type 2
TgenePRKCBchr6:34574331chr16:24043456ENST000004980580236_86058.0Zinc fingerPhorbol-ester/DAG-type 1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgenePRKCBchr6:34574331chr16:24043456ENST0000030353121736_8696674.0Zinc fingerPhorbol-ester/DAG-type 1
TgenePRKCBchr6:34574331chr16:24043456ENST0000032172821736_8696672.0Zinc fingerPhorbol-ester/DAG-type 1


Top

Fusion Gene Sequence for C6orf106-PRKCB


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>11915_11915_1_C6orf106-PRKCB_C6orf106_chr6_34574331_ENST00000374023_PRKCB_chr16_24043456_ENST00000303531_length(transcript)=8634nt_BP=1105nt
GGCGGAGTGGCGAGAGGCGAGAGGCGGCGGAGGCGGCGGAGCTGGGGGGGGTGGGAGGGGGGGGAGAGTGAGTGAGTGGCAGAGTGAGTT
TACCCCTATGAGACTGTGAGAGGCCCGGGGCCTACCTCAAAGGAGCGGGGTCGCGAAGCTAGCTAGCAGCGGCCCCCCTCCAGGTCCCCG
GGCCCGGCGGCGCGGCGGCGGCTTGGTTGTGAAGAGGCGGGGAAGCGGGTGTCCGGTCCCCGCCATGGAGGGCATGGACGTAGACCTGGA
CCCGGAGCTGATGCAGAAGTTCAGCTGCCTGGGCACCACCGACAAGGACGTGCTCATCTCCGAGTTCCAGAGGCTGCTCGGCTTCCAGCT
CAATCCTGCCGGTTGCGCCTTCTTCCTGGACATGACCAACTGGAACCTACAAGCAGCAATTGGCGCCTATTATGACTTTGAGAGCCCAAA
CATCAGTGTGCCCTCTATGTCCTTTGTTGAAGATGTCACCATAGGAGAAGGGGAGTCAATACCTCCGGATACTCAGTTTGTAAAAACATG
GCGGATCCAGAATTCTGGGGCAGAGGCCTGGCCTCCAGGGGTTTGTCTTAAATATGTCGGGGGAGACCAATTTGGACATGTGAACATGGT
GATGGTGAGATCGCTAGAGCCCCAAGAGATTGCAGATGTCAGCGTCCAGATGTGCAGCCCCAGCAGAGCAGGAATGTATCAGGGACAGTG
GCGGATGTGCACTGCTACAGGACTCTACTATGGAGATGTCATCTGGGTGATTCTCAGTGTGGAGGTGGGTGGACTTTTAGGAGTAACGCA
GCAGCTGTCATCTTTTGAAACGGAGTTCAACACACAGCCGCATCGTAAGGTAGAAGGAAACTTCAACCCTTTTGCCTCTCCCCAAAAGAA
CCGACAATCAGATGAAAACAACTTAAAAGACCCTGGGGGCTCCGAGTTCGACTCGATCAGCAAAAACACATGGGCTCCTGCTCCTGACAC
ATGGGCTCCTGCTCCTGACCAAACTGAGCAAGACCAGAATAGACTGTCACAGAACTCTGTAAATCTGTCTCCCAGCAGTCACGCAAACAA
CTTATCAGTAGTGACTTACAGTAAGGACCCCCGCAGCAAACACAAGTTTAAGATCCACACGTACTCCAGCCCCACGTTTTGTGACCACTG
TGGGTCACTGCTGTATGGACTCATCCACCAGGGGATGAAATGTGACACCTGCATGATGAATGTGCACAAGCGCTGCGTGATGAATGTTCC
CAGCCTGTGTGGCACGGACCACACGGAGCGCCGCGGCCGCATCTACATCCAGGCCCACATCGACAGGGACGTCCTCATTGTCCTCGTAAG
AGATGCTAAAAACCTTGTACCTATGGACCCCAATGGCCTGTCAGATCCCTACGTAAAACTGAAACTGATTCCCGATCCCAAAAGTGAGAG
CAAACAGAAGACCAAAACCATCAAATGCTCCCTCAACCCTGAGTGGAATGAGACATTTAGATTTCAGCTGAAAGAATCGGACAAAGACAG
AAGACTGTCAGTAGAGATTTGGGATTGGGATTTGACCAGCAGGAATGACTTCATGGGATCTTTGTCCTTTGGGATTTCTGAACTTCAGAA
AGCCAGTGTTGATGGCTGGTTTAAGTTACTGAGCCAGGAGGAAGGCGAGTACTTCAATGTGCCTGTGCCACCAGAAGGAAGTGAGGCCAA
TGAAGAACTGCGGCAGAAATTTGAGAGGGCCAAGATCAGTCAGGGAACCAAGGTCCCGGAAGAAAAGACGACCAACACTGTCTCCAAATT
TGACAACAATGGCAACAGAGACCGGATGAAACTGACCGATTTTAACTTCCTAATGGTGCTGGGGAAAGGCAGCTTTGGCAAGGTCATGCT
TTCAGAACGAAAAGGCACAGATGAGCTCTATGCTGTGAAGATCCTGAAGAAGGACGTTGTGATCCAAGATGATGACGTGGAGTGCACTAT
GGTGGAGAAGCGGGTGTTGGCCCTGCCTGGGAAGCCGCCCTTCCTGACCCAGCTCCACTCCTGCTTCCAGACCATGGACCGCCTGTACTT
TGTGATGGAGTACGTGAATGGGGGCGACCTCATGTATCACATCCAGCAAGTCGGCCGGTTCAAGGAGCCCCATGCTGTATTTTACGCTGC
AGAAATTGCCATCGGTCTGTTCTTCTTACAGAGTAAGGGCATCATTTACCGTGACCTAAAACTTGACAACGTGATGCTCGATTCTGAGGG
ACACATCAAGATTGCCGATTTTGGCATGTGTAAGGAAAACATCTGGGATGGGGTGACAACCAAGACATTCTGTGGCACTCCAGACTACAT
CGCCCCCGAGATAATTGCTTATCAGCCCTATGGGAAGTCCGTGGATTGGTGGGCATTTGGAGTCCTGCTGTATGAAATGTTGGCTGGGCA
GGCACCCTTTGAAGGGGAGGATGAAGATGAACTCTTCCAATCCATCATGGAACACAACGTAGCCTATCCCAAGTCTATGTCCAAGGAAGC
TGTGGCCATCTGCAAAGGGCTGATGACCAAACACCCAGGCAAACGTCTGGGTTGTGGACCTGAAGGCGAACGTGATATCAAAGAGCATGC
ATTTTTCCGGTATATTGATTGGGAGAAACTTGAACGCAAAGAGATCCAGCCCCCTTATAAGCCAAAAGCTTGTGGGCGAAATGCTGAAAA
CTTCGACCGATTTTTCACCCGCCATCCACCAGTCCTAACACCTCCCGACCAGGAAGTCATCAGGAATATTGACCAATCAGAATTCGAAGG
ATTTTCCTTTGTTAACTCTGAATTTTTAAAACCCGAAGTCAAGAGCTAAGTAGATGTGTAGATCTCCGTCCTTCATTTCTGTCATTCAAG
CTCAACGGCTATTGTGGTGACATTTTTATGTTTTTCATTGCCAAGTTGCATCCATGTTTGATTTTCTGATGAGACTAGAGTGACAGTGTT
TCAGAACCCAAATGTCCTCAGGTAGTTTGGAGCATCTCTATGAGATGGGATTATGCAGATGGCCTATGGAAAATGCAGCTGCATAATTAA
CACATTATCAAAGTCCTCTTACAATTTATTTTCCGCAGCATGTCAGCTAAGTAGACCCAATGGGGAGAGAAAATGCCTGCTTTCTTTCCC
TCTTTTTCTGCACTGCCATATTCACCCCCAACCATCCAATCTGTGGATAATTGGATGTTAGCGGTACTCTTCCACTTCCGGGCCTGGAGC
TTGGCTTGTATCCAAGTGTATGGTTGCTTTGCCTAAGAGGAATCCCTCTATTTCACCTGTTCTGGAGGCACCAGACCTTGAAAAGAACAT
GCTCAAAATAAAATGTTATCTGTTATTTTTGTAAACTCAAAGTTAAGATGATCAAAGTTCTAAAATTCCAAGAATGTGCTTTTAGACGGT
CTCAATCTAAAAGCACTTCAAGGGGTCAAAGGGCAACCAGCTTGGGTGCTACCTCAGTGTTGTAGTTTCTGATACTTTATGTCTTTGCTC
ACCCTCATCCCCAAACTACTTGAAAAGGGCATTTGGCACCACTCTCTGAAACAACACAGTCACTCTAGCAAGGCCCCCAAAGGGCCCTGG
TTTTACATTACATTTCAAACTTTATTTGCTTTGGGGTTTTGTTTCTGTTGTTGTTCAAATGCAAAAAAAAGAAAAAAAAAGAAAAAAAAA
GGTGACTCACATTGTTACACATGCTTTAAAATATGTATTCAAATGTTATTAACCACAATGACGACCTGCTTTGATTTAACCAAGAAGACG
GCTGCGGAGCCTAGCAGACTCAGGCCTGTGGGAATGGGATTTGTTACAAATCTAGGTTTGTTACTGGCTTCAGAAAGCTAATTAAGTGCT
CTGAAAAAGACACCGTTTCTTGAAACAAAGATGGTTGTATTCCTCACTTTGATGTTGTTTTGCAAGATGTTTGTGGAAATGTTCATTTGT
ATCTGGATCTCTGTTATGTGCCATTTTTCTTCTAGCATCGAGATACAATAAAAAAAAAAAAAAAGAAAAGAAGAAGAAATACTATTTCAA
GGAAAACTGCTCTTTTTGAGAAACGTGGACCTAAACTACAAAGTGGGAACTGAGGAGGGAACTCAGGAGAAAGGAACTAACTGCGGAGCT
TTAATCTTGGCCCCAGTGTTCAGCCACTCGGAGGGGCGGGGGCTGTGGCCCATTCAGGGGCTGCTGGTGGGCTGTAGTGGGGTGGGATGA
CCTGGCCAGAGCCAACGAGGATACTGGAGCCCAAAGTCAAGTTTAGAGACCAGCTGGGAACGTGAATGGGGCTCTTGATTTTCTTATCAA
AATCACCACTCCTCCCAGCTTGGACTAAATATTCTTTCTAGCAAGCAGCTTTGTGAGCTCCCTGAAGCCCAAGGAAACCCTTCGGTGGGA
GAAATTTCATTTCTGTCTGAGAGGATTAAGGCAGCAGGTGACTCCCCCTCCTCGCCTGCCGTGTCCTGCTATTCTCAGGCAGCTCTAAGG
AGAATTCTTATCACAGTTCAAGTGATTTCCAGAAGTTCCAGGGCTTCTGAGAGACCATCAAGGGAACTTTAACAACTTGACAAATGTCCT
TGAAGTAAGATGCCTCATCTTTAGGGAAAAATGGGGTTTGGATTTCTGCTTAGGCAAAGTCTCCTGCAGTTCATCCTTCTCTGTCCTCTT
CTTGCTTCAGGCTTGGGGACCGTCCCTGCTGTCCCCACTGTGGTGGCAATCAGGACCTAAGGTGAAGCAAACTTGAAGTTCTATCTGACA
AGTTTAGGCAGTAAGAGAAGGAGGGAAATCGGAGCAAAGCTCCCTCACTTTATTGTTGAGAAACTGGCATCTGGAAAGAGGAAGGAATTT
GCCCAAAGTCAGTCAGCTGGGATAAAAACCTGGGTGTCCTGTCCAGAAAGTGCAGGGTGCTTTCTGCTCTGTAGCAAGGCAGCAGACATC
TCTGAGCCAGGCCCACCAACAGGCCCTTATCTGGTGGTTGGATCATGATCCCATTTTGCTTGGACATGCTCTCAGGAAGATAAAAACCAT
GGAGAAACACTAGGCCATTGACAAATGATCTGAGACAACTTTAGAAAACAATGTAGGATGAATGGAAAGAGAAAGAAAGGAAAGAAAGAA
GAAAAAGAAAGAAGGAAAGAAAGAAAGAGAAAGGAAGGAAGGAAAGAAGGAAGGAAAAGAAGGAAGGAAGGAAGGAATATAGTGTTATAA
ATACTGCACTCAACATTTTCCAAATTCTTGCCATTATTTTTCAAAAGTTTAATAGTTTGCAGAAATAGATACTCAAGCCAAAGTCTGTTT
TAGAGAAACTTTCCATGGAAAGTCAGAATTTCTACCACTTCCTTTTCTATCCACATTTCCAGTGCAGAAGAAACTGAGAAACAGAGCTTT
TTGAAGAGAGGACAGGGCCATAGCAACAAGGACCTTCTTGGGGGATTAATGGGAGGTCAGTAGAATTAATAACCCTCCTTGGATGAGTGC
TACTGTTTTCACATGGCTTCAGATGCTATCAACCTCAAAGAAATGATCTCAACAGAGAAGCTTATTCTCTCCCAACTTCTACGGTAAAAT
CCAGGAGTATTTTCTCTGGGGATCTGCCCACAGGACAAAGTCCATAAAAGCAAGTCCTGTCTGGACCATGTGGTTATCTGAAGCATTAGC
CATCACCAGCACAACAAACGGGGCAGGGCTTTCCAAGGTGGGGCTGGTCAGAAGGGAATCTTTGATAAGAGGCCCACAGGCAGGGAAAGC
GAAATAGGGTTGATGAGACCAGGGGAGACCTAAAAAAAAGGCAGCTTTGTGTCTTCTAGCTCCAAATATACCTGCCTTTTAGCTCACACA
CTGTCCTGGAGTTCTCAGACCTTTAGGGGCCCTAACACAGTTCAGTTCATACAGGGGTTCAAAAGGGACAGTGGCCCATTTGGGAGACCT
TTAGGATCAATGGGAATCAATTCCATTGTTTTGCCTCAGAGTAAAGTTTCTGGCTCGGGGACAATTATAAGTTGCAAAAAGGATAGAGGC
ATATCCCAAGTCTTCCTTCATTCCACAAATAATTACAAACAACCTACTGTGTGCCAGGCACTATTCTTAGCACTGGAAATACACTAGTGA
AGAAGCAGATGAGGACCCTGTTTATTGTTTCTCTCCAAGAAATTCTCCAAGAATATTGTTTCTTGGAGAGAAATAATAAATAAACAAGAC
AATTTCTGAAAGCAATAAGTGCAATCAAGATAATTAAAGGATGCTAAAGTGTGACTTGTGGGGATTGGGAGAGAGATGCACAGACAATAT
TAAAGAGGAGGCATTCGAGCTTTGTTGTGAACACCGGAAGTAACATGCCGAGCGCCTGGGGGATGGAAACTCCTATAGCACCCCACAGGC
TAACAGCAAGCAGGACAAGACAAAAAGGGCAGGTGGGACATGGTAGAGATGGACCCTACCCAGGAAACAGCTCCATCAGCATCTTAGCCT
GCCCCACTCTAGCCACACATACCCACGTGTGCTCCTGAGTTCAGTGTGCCCACCTCACTCCCACACCCTCACATAGACTTGGCAAGAGTA
AGGAGGGAACTCCATAGAGACATTTTACCTATCTCAGGGGAGCAGCCACAAAGAAGCAAGTCTTGTAAAAGGTCTTTTGCAAAGGAGAGT
GAACCCAGCAATGAGAGATCCTTAACAGCTAGTGCCCATTAGGGGGCTAAACCTAAAGCCTGGGTGGTGATGGCTCAAACGCTAATGAGT
CAGTGAATCCTTACCGACCCCCTGGCCTTTATAATCTGAGGCAACTTTGGCTGCAGCCCGGGAATGTGCAGGGCACTAGGGAATACAAGG
CCTTCTTCCCTGGTTGTCTTGTAATAAAACAGCCATGGGGTTGTCCCTCCAGTCCGAGAGACTGTGATGAGGCCTACATAGCAGCGATGT
GGTCAGGTAAAAATCAGGAACCCACTGAAATCTTGGGCAAGCCACCCTGCCTGCTTGTGCCTCGGTTCTCTCATATGTCATATATAGGAG
GTGAGGACTCCAGCTCCACCTGCCCCAGGTGGGTGTGGTGATGATGAGGAAAGACAAGAGGCTTGCAAGGACCCTGAAGAGGTCGGAGCA
TCATACAGATTCCTTTATTAGCCCACATTCTGATGTTCCCTGGTGAGACTTGCCCCAAGCAATTGCTAGTAAATGGGGGTTAATTTCTTC
TCCACCTCCCTACTGAACAAAAAAAGAAATGCCAGACTTACTAGGAGAATCGAGTTGCTTTGAGTTTCTTTTGTTTTGTTTTGTTTTGTT
TTGTTTTAAGGCTCCCCTTACACACCCTCCTTTAAGCTTTGGGTTTTCTCTCTTATAGTTTGTTGACACATGCTAAAAATGTCTTTGGAG
AGAACTTCTGCCTGATAAACACCCAATTCTAGACTGTGGGTGGATTTTCGAGCTGACGGTGGTCAATTCCTTTCATTAAGCAGTGATCTG
ATTTCTCCACATGGCCATTCTGCCTTCTTGGGGGCAGAGTAGATGGGCAGCAGTTCACCTTTTCAGAGAAAGAGGTCTTCTAGCCACCTG
GGCTGCTACTGAATGGTTTTCTCCAGGACGCTCTACCTAATGATTATTTCTATAACATTAAGCATGGTAATAAGTAGCTTCCAATTCAAT
TCATCCTAAAGCCAAAGAAAATACAGCAACACACACACACACACACACACACACACACACACACACACACACACACCACTTTATGGCAAT
TCTTAACTGACATTCAATGACTTACTTCTTTTCTTAGAAAATTTCCACCACATTTCTATCCCCAAGCCAACATACAATGTGAAATGAAAG
CCAGTGCGTGGAGTGCAGCTGCTAAAAATTTTCAGCACAGGGCTCTTTCTGACTCTGCTCATGAGATGGTATCAGCCACCCAATGACTGG
CGTATCTTGGTCCTGTGTCTTTCTTCTTACGCTGTGTTAATGTGTTTACTTTCCATTTGGCAGAGAGACAAGAGAGACACCTCCAACTTC
GACAAAGAGTTCACCAGACAGCCTGTGGAACTGACCCCCACTGATAAACTCTTCATCATGAACTTGGACCAAAATGAATTTGCTGGCTTC
TCTTATACTAACCCAGAGTTTGTCATTAATGTGTAGGTGAATGCAAACTCCATCGTTGAGCCTGGGGTGTAAGACTTCAAGCCAAGCGTA
TGTATCAATTCTAGTCTTCCAGGATTCACGGTGCACATGCTGGCATTCAACATGTGGAAAGCTTGTCTTAGAGGGCTTTTCTTTGTATGT
GTAGCTTGCTAGTTTGTTTTCTACATTTGAAAATGTTTAGTTTAGAATAAGCGCATTATCCAATTATAGAGGTACAATTTTCCAAACTTC
CAGAAACTCATCAAATGAACAGACAATGTCAAAACTACTGTGTCTGATACCAAAATGCTTCAGTATTTGTAATTTTTCAAGTCAGAAGCT
GATGTTCCTGGTAAAAGTTTTTACAGTTATTCTATAATATCTTCTTTGAATGCTAAGCATGAGCGATATTTTTAAAAATTGTGAGTAAGC

>11915_11915_1_C6orf106-PRKCB_C6orf106_chr6_34574331_ENST00000374023_PRKCB_chr16_24043456_ENST00000303531_length(amino acids)=878AA_BP=301
MVVKRRGSGCPVPAMEGMDVDLDPELMQKFSCLGTTDKDVLISEFQRLLGFQLNPAGCAFFLDMTNWNLQAAIGAYYDFESPNISVPSMS
FVEDVTIGEGESIPPDTQFVKTWRIQNSGAEAWPPGVCLKYVGGDQFGHVNMVMVRSLEPQEIADVSVQMCSPSRAGMYQGQWRMCTATG
LYYGDVIWVILSVEVGGLLGVTQQLSSFETEFNTQPHRKVEGNFNPFASPQKNRQSDENNLKDPGGSEFDSISKNTWAPAPDTWAPAPDQ
TEQDQNRLSQNSVNLSPSSHANNLSVVTYSKDPRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDH
TERRGRIYIQAHIDRDVLIVLVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRLSVEIW
DWDLTSRNDFMGSLSFGISELQKASVDGWFKLLSQEEGEYFNVPVPPEGSEANEELRQKFERAKISQGTKVPEEKTTNTVSKFDNNGNRD
RMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNG
GDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAY
QPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDW

--------------------------------------------------------------
>11915_11915_2_C6orf106-PRKCB_C6orf106_chr6_34574331_ENST00000374023_PRKCB_chr16_24043456_ENST00000321728_length(transcript)=3331nt_BP=1105nt
GGCGGAGTGGCGAGAGGCGAGAGGCGGCGGAGGCGGCGGAGCTGGGGGGGGTGGGAGGGGGGGGAGAGTGAGTGAGTGGCAGAGTGAGTT
TACCCCTATGAGACTGTGAGAGGCCCGGGGCCTACCTCAAAGGAGCGGGGTCGCGAAGCTAGCTAGCAGCGGCCCCCCTCCAGGTCCCCG
GGCCCGGCGGCGCGGCGGCGGCTTGGTTGTGAAGAGGCGGGGAAGCGGGTGTCCGGTCCCCGCCATGGAGGGCATGGACGTAGACCTGGA
CCCGGAGCTGATGCAGAAGTTCAGCTGCCTGGGCACCACCGACAAGGACGTGCTCATCTCCGAGTTCCAGAGGCTGCTCGGCTTCCAGCT
CAATCCTGCCGGTTGCGCCTTCTTCCTGGACATGACCAACTGGAACCTACAAGCAGCAATTGGCGCCTATTATGACTTTGAGAGCCCAAA
CATCAGTGTGCCCTCTATGTCCTTTGTTGAAGATGTCACCATAGGAGAAGGGGAGTCAATACCTCCGGATACTCAGTTTGTAAAAACATG
GCGGATCCAGAATTCTGGGGCAGAGGCCTGGCCTCCAGGGGTTTGTCTTAAATATGTCGGGGGAGACCAATTTGGACATGTGAACATGGT
GATGGTGAGATCGCTAGAGCCCCAAGAGATTGCAGATGTCAGCGTCCAGATGTGCAGCCCCAGCAGAGCAGGAATGTATCAGGGACAGTG
GCGGATGTGCACTGCTACAGGACTCTACTATGGAGATGTCATCTGGGTGATTCTCAGTGTGGAGGTGGGTGGACTTTTAGGAGTAACGCA
GCAGCTGTCATCTTTTGAAACGGAGTTCAACACACAGCCGCATCGTAAGGTAGAAGGAAACTTCAACCCTTTTGCCTCTCCCCAAAAGAA
CCGACAATCAGATGAAAACAACTTAAAAGACCCTGGGGGCTCCGAGTTCGACTCGATCAGCAAAAACACATGGGCTCCTGCTCCTGACAC
ATGGGCTCCTGCTCCTGACCAAACTGAGCAAGACCAGAATAGACTGTCACAGAACTCTGTAAATCTGTCTCCCAGCAGTCACGCAAACAA
CTTATCAGTAGTGACTTACAGTAAGGACCCCCGCAGCAAACACAAGTTTAAGATCCACACGTACTCCAGCCCCACGTTTTGTGACCACTG
TGGGTCACTGCTGTATGGACTCATCCACCAGGGGATGAAATGTGACACCTGCATGATGAATGTGCACAAGCGCTGCGTGATGAATGTTCC
CAGCCTGTGTGGCACGGACCACACGGAGCGCCGCGGCCGCATCTACATCCAGGCCCACATCGACAGGGACGTCCTCATTGTCCTCGTAAG
AGATGCTAAAAACCTTGTACCTATGGACCCCAATGGCCTGTCAGATCCCTACGTAAAACTGAAACTGATTCCCGATCCCAAAAGTGAGAG
CAAACAGAAGACCAAAACCATCAAATGCTCCCTCAACCCTGAGTGGAATGAGACATTTAGATTTCAGCTGAAAGAATCGGACAAAGACAG
AAGACTGTCAGTAGAGATTTGGGATTGGGATTTGACCAGCAGGAATGACTTCATGGGATCTTTGTCCTTTGGGATTTCTGAACTTCAGAA
AGCCAGTGTTGATGGCTGGTTTAAGTTACTGAGCCAGGAGGAAGGCGAGTACTTCAATGTGCCTGTGCCACCAGAAGGAAGTGAGGCCAA
TGAAGAACTGCGGCAGAAATTTGAGAGGGCCAAGATCAGTCAGGGAACCAAGGTCCCGGAAGAAAAGACGACCAACACTGTCTCCAAATT
TGACAACAATGGCAACAGAGACCGGATGAAACTGACCGATTTTAACTTCCTAATGGTGCTGGGGAAAGGCAGCTTTGGCAAGGTCATGCT
TTCAGAACGAAAAGGCACAGATGAGCTCTATGCTGTGAAGATCCTGAAGAAGGACGTTGTGATCCAAGATGATGACGTGGAGTGCACTAT
GGTGGAGAAGCGGGTGTTGGCCCTGCCTGGGAAGCCGCCCTTCCTGACCCAGCTCCACTCCTGCTTCCAGACCATGGACCGCCTGTACTT
TGTGATGGAGTACGTGAATGGGGGCGACCTCATGTATCACATCCAGCAAGTCGGCCGGTTCAAGGAGCCCCATGCTGTATTTTACGCTGC
AGAAATTGCCATCGGTCTGTTCTTCTTACAGAGTAAGGGCATCATTTACCGTGACCTAAAACTTGACAACGTGATGCTCGATTCTGAGGG
ACACATCAAGATTGCCGATTTTGGCATGTGTAAGGAAAACATCTGGGATGGGGTGACAACCAAGACATTCTGTGGCACTCCAGACTACAT
CGCCCCCGAGATAATTGCTTATCAGCCCTATGGGAAGTCCGTGGATTGGTGGGCATTTGGAGTCCTGCTGTATGAAATGTTGGCTGGGCA
GGCACCCTTTGAAGGGGAGGATGAAGATGAACTCTTCCAATCCATCATGGAACACAACGTAGCCTATCCCAAGTCTATGTCCAAGGAAGC
TGTGGCCATCTGCAAAGGGCTGATGACCAAACACCCAGGCAAACGTCTGGGTTGTGGACCTGAAGGCGAACGTGATATCAAAGAGCATGC
ATTTTTCCGGTATATTGATTGGGAGAAACTTGAACGCAAAGAGATCCAGCCCCCTTATAAGCCAAAAGCTAGAGACAAGAGAGACACCTC
CAACTTCGACAAAGAGTTCACCAGACAGCCTGTGGAACTGACCCCCACTGATAAACTCTTCATCATGAACTTGGACCAAAATGAATTTGC
TGGCTTCTCTTATACTAACCCAGAGTTTGTCATTAATGTGTAGGTGAATGCAAACTCCATCGTTGAGCCTGGGGTGTAAGACTTCAAGCC
AAGCGTATGTATCAATTCTAGTCTTCCAGGATTCACGGTGCACATGCTGGCATTCAACATGTGGAAAGCTTGTCTTAGAGGGCTTTTCTT
TGTATGTGTAGCTTGCTAGTTTGTTTTCTACATTTGAAAATGTTTAGTTTAGAATAAGCGCATTATCCAATTATAGAGGTACAATTTTCC
AAACTTCCAGAAACTCATCAAATGAACAGACAATGTCAAAACTACTGTGTCTGATACCAAAATGCTTCAGTATTTGTAATTTTTCAAGTC
AGAAGCTGATGTTCCTGGTAAAAGTTTTTACAGTTATTCTATAATATCTTCTTTGAATGCTAAGCATGAGCGATATTTTTAAAAATTGTG
AGTAAGCTTTGCAGTTACTGTGAACTATTGTCTCTTGGAGGAAGTTTTTTGTTTAAGAATTGATATGATTAAACTGAATTAATATATGCA

>11915_11915_2_C6orf106-PRKCB_C6orf106_chr6_34574331_ENST00000374023_PRKCB_chr16_24043456_ENST00000321728_length(amino acids)=876AA_BP=301
MVVKRRGSGCPVPAMEGMDVDLDPELMQKFSCLGTTDKDVLISEFQRLLGFQLNPAGCAFFLDMTNWNLQAAIGAYYDFESPNISVPSMS
FVEDVTIGEGESIPPDTQFVKTWRIQNSGAEAWPPGVCLKYVGGDQFGHVNMVMVRSLEPQEIADVSVQMCSPSRAGMYQGQWRMCTATG
LYYGDVIWVILSVEVGGLLGVTQQLSSFETEFNTQPHRKVEGNFNPFASPQKNRQSDENNLKDPGGSEFDSISKNTWAPAPDTWAPAPDQ
TEQDQNRLSQNSVNLSPSSHANNLSVVTYSKDPRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDH
TERRGRIYIQAHIDRDVLIVLVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRLSVEIW
DWDLTSRNDFMGSLSFGISELQKASVDGWFKLLSQEEGEYFNVPVPPEGSEANEELRQKFERAKISQGTKVPEEKTTNTVSKFDNNGNRD
RMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVMEYVNG
GDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAY
QPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFFRYIDW

--------------------------------------------------------------
>11915_11915_3_C6orf106-PRKCB_C6orf106_chr6_34574331_ENST00000374026_PRKCB_chr16_24043456_ENST00000303531_length(transcript)=8448nt_BP=919nt
GGAGGCGGAGGCGGCGGAGTGGCGAGAGGCGAGAGGCGGCGGAGGCGGCGGAGCTGGGGGGGGTGGGAGGGGGGGGAGAGTGAGTGAGTG
GCAGAGTGAGTTTACCCCTATGAGACTGTGAGAGGCCCGGGGCCTACCTCAAAGGAGCGGGGTCGCGAAGCTAGCTAGCAGCGGCCCCCC
TCCAGGTCCCCGGGCCCGGCGGCGCGGCGGCGGCTTGGTTGTGAAGAGGCGGGGAAGCGGGTGTCCGGTCCCCGCCATGGAGGGCATGGA
CGTAGACCTGGACCCGGAGCTGATGCAGAAGTTCAGCTGCCTGGGCACCACCGACAAGGACGTGCTCATCTCCGAGTTCCAGAGGCTGCT
CGGCTTCCAGCTCAATCCTGCCGGTTGCGCCTTCTTCCTGGACATGACCAACTGGAACCTACAAGCAGCAATTGGCGCCTATTATGACTT
TGAGAGCCCAAACATCAGTGTGCCCTCTATGTCCTTTGTTGAAGATGTCACCATAGGAGAAGGGGAGTCAATACCTCCGGATACTCAGTT
TGTAAAAACATGGCGGATCCAGAATTCTGATGTCATCTGGGTGATTCTCAGTGTGGAGGTGGGTGGACTTTTAGGAGTAACGCAGCAGCT
GTCATCTTTTGAAACGGAGTTCAACACACAGCCGCATCGTAAGGTAGAAGGAAACTTCAACCCTTTTGCCTCTCCCCAAAAGAACCGACA
ATCAGATGAAAACAACTTAAAAGACCCTGGGGGCTCCGAGTTCGACTCGATCAGCAAAAACACATGGGCTCCTGCTCCTGACACATGGGC
TCCTGCTCCTGACCAAACTGAGCAAGACCAGAATAGACTGTCACAGAACTCTGTAAATCTGTCTCCCAGCAGTCACGCAAACAACTTATC
AGTAGTGACTTACAGTAAGGACCCCCGCAGCAAACACAAGTTTAAGATCCACACGTACTCCAGCCCCACGTTTTGTGACCACTGTGGGTC
ACTGCTGTATGGACTCATCCACCAGGGGATGAAATGTGACACCTGCATGATGAATGTGCACAAGCGCTGCGTGATGAATGTTCCCAGCCT
GTGTGGCACGGACCACACGGAGCGCCGCGGCCGCATCTACATCCAGGCCCACATCGACAGGGACGTCCTCATTGTCCTCGTAAGAGATGC
TAAAAACCTTGTACCTATGGACCCCAATGGCCTGTCAGATCCCTACGTAAAACTGAAACTGATTCCCGATCCCAAAAGTGAGAGCAAACA
GAAGACCAAAACCATCAAATGCTCCCTCAACCCTGAGTGGAATGAGACATTTAGATTTCAGCTGAAAGAATCGGACAAAGACAGAAGACT
GTCAGTAGAGATTTGGGATTGGGATTTGACCAGCAGGAATGACTTCATGGGATCTTTGTCCTTTGGGATTTCTGAACTTCAGAAAGCCAG
TGTTGATGGCTGGTTTAAGTTACTGAGCCAGGAGGAAGGCGAGTACTTCAATGTGCCTGTGCCACCAGAAGGAAGTGAGGCCAATGAAGA
ACTGCGGCAGAAATTTGAGAGGGCCAAGATCAGTCAGGGAACCAAGGTCCCGGAAGAAAAGACGACCAACACTGTCTCCAAATTTGACAA
CAATGGCAACAGAGACCGGATGAAACTGACCGATTTTAACTTCCTAATGGTGCTGGGGAAAGGCAGCTTTGGCAAGGTCATGCTTTCAGA
ACGAAAAGGCACAGATGAGCTCTATGCTGTGAAGATCCTGAAGAAGGACGTTGTGATCCAAGATGATGACGTGGAGTGCACTATGGTGGA
GAAGCGGGTGTTGGCCCTGCCTGGGAAGCCGCCCTTCCTGACCCAGCTCCACTCCTGCTTCCAGACCATGGACCGCCTGTACTTTGTGAT
GGAGTACGTGAATGGGGGCGACCTCATGTATCACATCCAGCAAGTCGGCCGGTTCAAGGAGCCCCATGCTGTATTTTACGCTGCAGAAAT
TGCCATCGGTCTGTTCTTCTTACAGAGTAAGGGCATCATTTACCGTGACCTAAAACTTGACAACGTGATGCTCGATTCTGAGGGACACAT
CAAGATTGCCGATTTTGGCATGTGTAAGGAAAACATCTGGGATGGGGTGACAACCAAGACATTCTGTGGCACTCCAGACTACATCGCCCC
CGAGATAATTGCTTATCAGCCCTATGGGAAGTCCGTGGATTGGTGGGCATTTGGAGTCCTGCTGTATGAAATGTTGGCTGGGCAGGCACC
CTTTGAAGGGGAGGATGAAGATGAACTCTTCCAATCCATCATGGAACACAACGTAGCCTATCCCAAGTCTATGTCCAAGGAAGCTGTGGC
CATCTGCAAAGGGCTGATGACCAAACACCCAGGCAAACGTCTGGGTTGTGGACCTGAAGGCGAACGTGATATCAAAGAGCATGCATTTTT
CCGGTATATTGATTGGGAGAAACTTGAACGCAAAGAGATCCAGCCCCCTTATAAGCCAAAAGCTTGTGGGCGAAATGCTGAAAACTTCGA
CCGATTTTTCACCCGCCATCCACCAGTCCTAACACCTCCCGACCAGGAAGTCATCAGGAATATTGACCAATCAGAATTCGAAGGATTTTC
CTTTGTTAACTCTGAATTTTTAAAACCCGAAGTCAAGAGCTAAGTAGATGTGTAGATCTCCGTCCTTCATTTCTGTCATTCAAGCTCAAC
GGCTATTGTGGTGACATTTTTATGTTTTTCATTGCCAAGTTGCATCCATGTTTGATTTTCTGATGAGACTAGAGTGACAGTGTTTCAGAA
CCCAAATGTCCTCAGGTAGTTTGGAGCATCTCTATGAGATGGGATTATGCAGATGGCCTATGGAAAATGCAGCTGCATAATTAACACATT
ATCAAAGTCCTCTTACAATTTATTTTCCGCAGCATGTCAGCTAAGTAGACCCAATGGGGAGAGAAAATGCCTGCTTTCTTTCCCTCTTTT
TCTGCACTGCCATATTCACCCCCAACCATCCAATCTGTGGATAATTGGATGTTAGCGGTACTCTTCCACTTCCGGGCCTGGAGCTTGGCT
TGTATCCAAGTGTATGGTTGCTTTGCCTAAGAGGAATCCCTCTATTTCACCTGTTCTGGAGGCACCAGACCTTGAAAAGAACATGCTCAA
AATAAAATGTTATCTGTTATTTTTGTAAACTCAAAGTTAAGATGATCAAAGTTCTAAAATTCCAAGAATGTGCTTTTAGACGGTCTCAAT
CTAAAAGCACTTCAAGGGGTCAAAGGGCAACCAGCTTGGGTGCTACCTCAGTGTTGTAGTTTCTGATACTTTATGTCTTTGCTCACCCTC
ATCCCCAAACTACTTGAAAAGGGCATTTGGCACCACTCTCTGAAACAACACAGTCACTCTAGCAAGGCCCCCAAAGGGCCCTGGTTTTAC
ATTACATTTCAAACTTTATTTGCTTTGGGGTTTTGTTTCTGTTGTTGTTCAAATGCAAAAAAAAGAAAAAAAAAGAAAAAAAAAGGTGAC
TCACATTGTTACACATGCTTTAAAATATGTATTCAAATGTTATTAACCACAATGACGACCTGCTTTGATTTAACCAAGAAGACGGCTGCG
GAGCCTAGCAGACTCAGGCCTGTGGGAATGGGATTTGTTACAAATCTAGGTTTGTTACTGGCTTCAGAAAGCTAATTAAGTGCTCTGAAA
AAGACACCGTTTCTTGAAACAAAGATGGTTGTATTCCTCACTTTGATGTTGTTTTGCAAGATGTTTGTGGAAATGTTCATTTGTATCTGG
ATCTCTGTTATGTGCCATTTTTCTTCTAGCATCGAGATACAATAAAAAAAAAAAAAAAGAAAAGAAGAAGAAATACTATTTCAAGGAAAA
CTGCTCTTTTTGAGAAACGTGGACCTAAACTACAAAGTGGGAACTGAGGAGGGAACTCAGGAGAAAGGAACTAACTGCGGAGCTTTAATC
TTGGCCCCAGTGTTCAGCCACTCGGAGGGGCGGGGGCTGTGGCCCATTCAGGGGCTGCTGGTGGGCTGTAGTGGGGTGGGATGACCTGGC
CAGAGCCAACGAGGATACTGGAGCCCAAAGTCAAGTTTAGAGACCAGCTGGGAACGTGAATGGGGCTCTTGATTTTCTTATCAAAATCAC
CACTCCTCCCAGCTTGGACTAAATATTCTTTCTAGCAAGCAGCTTTGTGAGCTCCCTGAAGCCCAAGGAAACCCTTCGGTGGGAGAAATT
TCATTTCTGTCTGAGAGGATTAAGGCAGCAGGTGACTCCCCCTCCTCGCCTGCCGTGTCCTGCTATTCTCAGGCAGCTCTAAGGAGAATT
CTTATCACAGTTCAAGTGATTTCCAGAAGTTCCAGGGCTTCTGAGAGACCATCAAGGGAACTTTAACAACTTGACAAATGTCCTTGAAGT
AAGATGCCTCATCTTTAGGGAAAAATGGGGTTTGGATTTCTGCTTAGGCAAAGTCTCCTGCAGTTCATCCTTCTCTGTCCTCTTCTTGCT
TCAGGCTTGGGGACCGTCCCTGCTGTCCCCACTGTGGTGGCAATCAGGACCTAAGGTGAAGCAAACTTGAAGTTCTATCTGACAAGTTTA
GGCAGTAAGAGAAGGAGGGAAATCGGAGCAAAGCTCCCTCACTTTATTGTTGAGAAACTGGCATCTGGAAAGAGGAAGGAATTTGCCCAA
AGTCAGTCAGCTGGGATAAAAACCTGGGTGTCCTGTCCAGAAAGTGCAGGGTGCTTTCTGCTCTGTAGCAAGGCAGCAGACATCTCTGAG
CCAGGCCCACCAACAGGCCCTTATCTGGTGGTTGGATCATGATCCCATTTTGCTTGGACATGCTCTCAGGAAGATAAAAACCATGGAGAA
ACACTAGGCCATTGACAAATGATCTGAGACAACTTTAGAAAACAATGTAGGATGAATGGAAAGAGAAAGAAAGGAAAGAAAGAAGAAAAA
GAAAGAAGGAAAGAAAGAAAGAGAAAGGAAGGAAGGAAAGAAGGAAGGAAAAGAAGGAAGGAAGGAAGGAATATAGTGTTATAAATACTG
CACTCAACATTTTCCAAATTCTTGCCATTATTTTTCAAAAGTTTAATAGTTTGCAGAAATAGATACTCAAGCCAAAGTCTGTTTTAGAGA
AACTTTCCATGGAAAGTCAGAATTTCTACCACTTCCTTTTCTATCCACATTTCCAGTGCAGAAGAAACTGAGAAACAGAGCTTTTTGAAG
AGAGGACAGGGCCATAGCAACAAGGACCTTCTTGGGGGATTAATGGGAGGTCAGTAGAATTAATAACCCTCCTTGGATGAGTGCTACTGT
TTTCACATGGCTTCAGATGCTATCAACCTCAAAGAAATGATCTCAACAGAGAAGCTTATTCTCTCCCAACTTCTACGGTAAAATCCAGGA
GTATTTTCTCTGGGGATCTGCCCACAGGACAAAGTCCATAAAAGCAAGTCCTGTCTGGACCATGTGGTTATCTGAAGCATTAGCCATCAC
CAGCACAACAAACGGGGCAGGGCTTTCCAAGGTGGGGCTGGTCAGAAGGGAATCTTTGATAAGAGGCCCACAGGCAGGGAAAGCGAAATA
GGGTTGATGAGACCAGGGGAGACCTAAAAAAAAGGCAGCTTTGTGTCTTCTAGCTCCAAATATACCTGCCTTTTAGCTCACACACTGTCC
TGGAGTTCTCAGACCTTTAGGGGCCCTAACACAGTTCAGTTCATACAGGGGTTCAAAAGGGACAGTGGCCCATTTGGGAGACCTTTAGGA
TCAATGGGAATCAATTCCATTGTTTTGCCTCAGAGTAAAGTTTCTGGCTCGGGGACAATTATAAGTTGCAAAAAGGATAGAGGCATATCC
CAAGTCTTCCTTCATTCCACAAATAATTACAAACAACCTACTGTGTGCCAGGCACTATTCTTAGCACTGGAAATACACTAGTGAAGAAGC
AGATGAGGACCCTGTTTATTGTTTCTCTCCAAGAAATTCTCCAAGAATATTGTTTCTTGGAGAGAAATAATAAATAAACAAGACAATTTC
TGAAAGCAATAAGTGCAATCAAGATAATTAAAGGATGCTAAAGTGTGACTTGTGGGGATTGGGAGAGAGATGCACAGACAATATTAAAGA
GGAGGCATTCGAGCTTTGTTGTGAACACCGGAAGTAACATGCCGAGCGCCTGGGGGATGGAAACTCCTATAGCACCCCACAGGCTAACAG
CAAGCAGGACAAGACAAAAAGGGCAGGTGGGACATGGTAGAGATGGACCCTACCCAGGAAACAGCTCCATCAGCATCTTAGCCTGCCCCA
CTCTAGCCACACATACCCACGTGTGCTCCTGAGTTCAGTGTGCCCACCTCACTCCCACACCCTCACATAGACTTGGCAAGAGTAAGGAGG
GAACTCCATAGAGACATTTTACCTATCTCAGGGGAGCAGCCACAAAGAAGCAAGTCTTGTAAAAGGTCTTTTGCAAAGGAGAGTGAACCC
AGCAATGAGAGATCCTTAACAGCTAGTGCCCATTAGGGGGCTAAACCTAAAGCCTGGGTGGTGATGGCTCAAACGCTAATGAGTCAGTGA
ATCCTTACCGACCCCCTGGCCTTTATAATCTGAGGCAACTTTGGCTGCAGCCCGGGAATGTGCAGGGCACTAGGGAATACAAGGCCTTCT
TCCCTGGTTGTCTTGTAATAAAACAGCCATGGGGTTGTCCCTCCAGTCCGAGAGACTGTGATGAGGCCTACATAGCAGCGATGTGGTCAG
GTAAAAATCAGGAACCCACTGAAATCTTGGGCAAGCCACCCTGCCTGCTTGTGCCTCGGTTCTCTCATATGTCATATATAGGAGGTGAGG
ACTCCAGCTCCACCTGCCCCAGGTGGGTGTGGTGATGATGAGGAAAGACAAGAGGCTTGCAAGGACCCTGAAGAGGTCGGAGCATCATAC
AGATTCCTTTATTAGCCCACATTCTGATGTTCCCTGGTGAGACTTGCCCCAAGCAATTGCTAGTAAATGGGGGTTAATTTCTTCTCCACC
TCCCTACTGAACAAAAAAAGAAATGCCAGACTTACTAGGAGAATCGAGTTGCTTTGAGTTTCTTTTGTTTTGTTTTGTTTTGTTTTGTTT
TAAGGCTCCCCTTACACACCCTCCTTTAAGCTTTGGGTTTTCTCTCTTATAGTTTGTTGACACATGCTAAAAATGTCTTTGGAGAGAACT
TCTGCCTGATAAACACCCAATTCTAGACTGTGGGTGGATTTTCGAGCTGACGGTGGTCAATTCCTTTCATTAAGCAGTGATCTGATTTCT
CCACATGGCCATTCTGCCTTCTTGGGGGCAGAGTAGATGGGCAGCAGTTCACCTTTTCAGAGAAAGAGGTCTTCTAGCCACCTGGGCTGC
TACTGAATGGTTTTCTCCAGGACGCTCTACCTAATGATTATTTCTATAACATTAAGCATGGTAATAAGTAGCTTCCAATTCAATTCATCC
TAAAGCCAAAGAAAATACAGCAACACACACACACACACACACACACACACACACACACACACACACACACCACTTTATGGCAATTCTTAA
CTGACATTCAATGACTTACTTCTTTTCTTAGAAAATTTCCACCACATTTCTATCCCCAAGCCAACATACAATGTGAAATGAAAGCCAGTG
CGTGGAGTGCAGCTGCTAAAAATTTTCAGCACAGGGCTCTTTCTGACTCTGCTCATGAGATGGTATCAGCCACCCAATGACTGGCGTATC
TTGGTCCTGTGTCTTTCTTCTTACGCTGTGTTAATGTGTTTACTTTCCATTTGGCAGAGAGACAAGAGAGACACCTCCAACTTCGACAAA
GAGTTCACCAGACAGCCTGTGGAACTGACCCCCACTGATAAACTCTTCATCATGAACTTGGACCAAAATGAATTTGCTGGCTTCTCTTAT
ACTAACCCAGAGTTTGTCATTAATGTGTAGGTGAATGCAAACTCCATCGTTGAGCCTGGGGTGTAAGACTTCAAGCCAAGCGTATGTATC
AATTCTAGTCTTCCAGGATTCACGGTGCACATGCTGGCATTCAACATGTGGAAAGCTTGTCTTAGAGGGCTTTTCTTTGTATGTGTAGCT
TGCTAGTTTGTTTTCTACATTTGAAAATGTTTAGTTTAGAATAAGCGCATTATCCAATTATAGAGGTACAATTTTCCAAACTTCCAGAAA
CTCATCAAATGAACAGACAATGTCAAAACTACTGTGTCTGATACCAAAATGCTTCAGTATTTGTAATTTTTCAAGTCAGAAGCTGATGTT
CCTGGTAAAAGTTTTTACAGTTATTCTATAATATCTTCTTTGAATGCTAAGCATGAGCGATATTTTTAAAAATTGTGAGTAAGCTTTGCA

>11915_11915_3_C6orf106-PRKCB_C6orf106_chr6_34574331_ENST00000374026_PRKCB_chr16_24043456_ENST00000303531_length(amino acids)=812AA_BP=235
MVVKRRGSGCPVPAMEGMDVDLDPELMQKFSCLGTTDKDVLISEFQRLLGFQLNPAGCAFFLDMTNWNLQAAIGAYYDFESPNISVPSMS
FVEDVTIGEGESIPPDTQFVKTWRIQNSDVIWVILSVEVGGLLGVTQQLSSFETEFNTQPHRKVEGNFNPFASPQKNRQSDENNLKDPGG
SEFDSISKNTWAPAPDTWAPAPDQTEQDQNRLSQNSVNLSPSSHANNLSVVTYSKDPRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMK
CDTCMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIDRDVLIVLVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNP
EWNETFRFQLKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKASVDGWFKLLSQEEGEYFNVPVPPEGSEANEELRQKFERAKIS
QGTKVPEEKTTNTVSKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPP
FLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKEN
IWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPG
KRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKACGRNAENFDRFFTRHPPVLTPPDQEVIRNIDQSEFEGFSFVNSEFLKPEV

--------------------------------------------------------------
>11915_11915_4_C6orf106-PRKCB_C6orf106_chr6_34574331_ENST00000374026_PRKCB_chr16_24043456_ENST00000321728_length(transcript)=3145nt_BP=919nt
GGAGGCGGAGGCGGCGGAGTGGCGAGAGGCGAGAGGCGGCGGAGGCGGCGGAGCTGGGGGGGGTGGGAGGGGGGGGAGAGTGAGTGAGTG
GCAGAGTGAGTTTACCCCTATGAGACTGTGAGAGGCCCGGGGCCTACCTCAAAGGAGCGGGGTCGCGAAGCTAGCTAGCAGCGGCCCCCC
TCCAGGTCCCCGGGCCCGGCGGCGCGGCGGCGGCTTGGTTGTGAAGAGGCGGGGAAGCGGGTGTCCGGTCCCCGCCATGGAGGGCATGGA
CGTAGACCTGGACCCGGAGCTGATGCAGAAGTTCAGCTGCCTGGGCACCACCGACAAGGACGTGCTCATCTCCGAGTTCCAGAGGCTGCT
CGGCTTCCAGCTCAATCCTGCCGGTTGCGCCTTCTTCCTGGACATGACCAACTGGAACCTACAAGCAGCAATTGGCGCCTATTATGACTT
TGAGAGCCCAAACATCAGTGTGCCCTCTATGTCCTTTGTTGAAGATGTCACCATAGGAGAAGGGGAGTCAATACCTCCGGATACTCAGTT
TGTAAAAACATGGCGGATCCAGAATTCTGATGTCATCTGGGTGATTCTCAGTGTGGAGGTGGGTGGACTTTTAGGAGTAACGCAGCAGCT
GTCATCTTTTGAAACGGAGTTCAACACACAGCCGCATCGTAAGGTAGAAGGAAACTTCAACCCTTTTGCCTCTCCCCAAAAGAACCGACA
ATCAGATGAAAACAACTTAAAAGACCCTGGGGGCTCCGAGTTCGACTCGATCAGCAAAAACACATGGGCTCCTGCTCCTGACACATGGGC
TCCTGCTCCTGACCAAACTGAGCAAGACCAGAATAGACTGTCACAGAACTCTGTAAATCTGTCTCCCAGCAGTCACGCAAACAACTTATC
AGTAGTGACTTACAGTAAGGACCCCCGCAGCAAACACAAGTTTAAGATCCACACGTACTCCAGCCCCACGTTTTGTGACCACTGTGGGTC
ACTGCTGTATGGACTCATCCACCAGGGGATGAAATGTGACACCTGCATGATGAATGTGCACAAGCGCTGCGTGATGAATGTTCCCAGCCT
GTGTGGCACGGACCACACGGAGCGCCGCGGCCGCATCTACATCCAGGCCCACATCGACAGGGACGTCCTCATTGTCCTCGTAAGAGATGC
TAAAAACCTTGTACCTATGGACCCCAATGGCCTGTCAGATCCCTACGTAAAACTGAAACTGATTCCCGATCCCAAAAGTGAGAGCAAACA
GAAGACCAAAACCATCAAATGCTCCCTCAACCCTGAGTGGAATGAGACATTTAGATTTCAGCTGAAAGAATCGGACAAAGACAGAAGACT
GTCAGTAGAGATTTGGGATTGGGATTTGACCAGCAGGAATGACTTCATGGGATCTTTGTCCTTTGGGATTTCTGAACTTCAGAAAGCCAG
TGTTGATGGCTGGTTTAAGTTACTGAGCCAGGAGGAAGGCGAGTACTTCAATGTGCCTGTGCCACCAGAAGGAAGTGAGGCCAATGAAGA
ACTGCGGCAGAAATTTGAGAGGGCCAAGATCAGTCAGGGAACCAAGGTCCCGGAAGAAAAGACGACCAACACTGTCTCCAAATTTGACAA
CAATGGCAACAGAGACCGGATGAAACTGACCGATTTTAACTTCCTAATGGTGCTGGGGAAAGGCAGCTTTGGCAAGGTCATGCTTTCAGA
ACGAAAAGGCACAGATGAGCTCTATGCTGTGAAGATCCTGAAGAAGGACGTTGTGATCCAAGATGATGACGTGGAGTGCACTATGGTGGA
GAAGCGGGTGTTGGCCCTGCCTGGGAAGCCGCCCTTCCTGACCCAGCTCCACTCCTGCTTCCAGACCATGGACCGCCTGTACTTTGTGAT
GGAGTACGTGAATGGGGGCGACCTCATGTATCACATCCAGCAAGTCGGCCGGTTCAAGGAGCCCCATGCTGTATTTTACGCTGCAGAAAT
TGCCATCGGTCTGTTCTTCTTACAGAGTAAGGGCATCATTTACCGTGACCTAAAACTTGACAACGTGATGCTCGATTCTGAGGGACACAT
CAAGATTGCCGATTTTGGCATGTGTAAGGAAAACATCTGGGATGGGGTGACAACCAAGACATTCTGTGGCACTCCAGACTACATCGCCCC
CGAGATAATTGCTTATCAGCCCTATGGGAAGTCCGTGGATTGGTGGGCATTTGGAGTCCTGCTGTATGAAATGTTGGCTGGGCAGGCACC
CTTTGAAGGGGAGGATGAAGATGAACTCTTCCAATCCATCATGGAACACAACGTAGCCTATCCCAAGTCTATGTCCAAGGAAGCTGTGGC
CATCTGCAAAGGGCTGATGACCAAACACCCAGGCAAACGTCTGGGTTGTGGACCTGAAGGCGAACGTGATATCAAAGAGCATGCATTTTT
CCGGTATATTGATTGGGAGAAACTTGAACGCAAAGAGATCCAGCCCCCTTATAAGCCAAAAGCTAGAGACAAGAGAGACACCTCCAACTT
CGACAAAGAGTTCACCAGACAGCCTGTGGAACTGACCCCCACTGATAAACTCTTCATCATGAACTTGGACCAAAATGAATTTGCTGGCTT
CTCTTATACTAACCCAGAGTTTGTCATTAATGTGTAGGTGAATGCAAACTCCATCGTTGAGCCTGGGGTGTAAGACTTCAAGCCAAGCGT
ATGTATCAATTCTAGTCTTCCAGGATTCACGGTGCACATGCTGGCATTCAACATGTGGAAAGCTTGTCTTAGAGGGCTTTTCTTTGTATG
TGTAGCTTGCTAGTTTGTTTTCTACATTTGAAAATGTTTAGTTTAGAATAAGCGCATTATCCAATTATAGAGGTACAATTTTCCAAACTT
CCAGAAACTCATCAAATGAACAGACAATGTCAAAACTACTGTGTCTGATACCAAAATGCTTCAGTATTTGTAATTTTTCAAGTCAGAAGC
TGATGTTCCTGGTAAAAGTTTTTACAGTTATTCTATAATATCTTCTTTGAATGCTAAGCATGAGCGATATTTTTAAAAATTGTGAGTAAG

>11915_11915_4_C6orf106-PRKCB_C6orf106_chr6_34574331_ENST00000374026_PRKCB_chr16_24043456_ENST00000321728_length(amino acids)=810AA_BP=235
MVVKRRGSGCPVPAMEGMDVDLDPELMQKFSCLGTTDKDVLISEFQRLLGFQLNPAGCAFFLDMTNWNLQAAIGAYYDFESPNISVPSMS
FVEDVTIGEGESIPPDTQFVKTWRIQNSDVIWVILSVEVGGLLGVTQQLSSFETEFNTQPHRKVEGNFNPFASPQKNRQSDENNLKDPGG
SEFDSISKNTWAPAPDTWAPAPDQTEQDQNRLSQNSVNLSPSSHANNLSVVTYSKDPRSKHKFKIHTYSSPTFCDHCGSLLYGLIHQGMK
CDTCMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIDRDVLIVLVRDAKNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNP
EWNETFRFQLKESDKDRRLSVEIWDWDLTSRNDFMGSLSFGISELQKASVDGWFKLLSQEEGEYFNVPVPPEGSEANEELRQKFERAKIS
QGTKVPEEKTTNTVSKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSERKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPP
FLTQLHSCFQTMDRLYFVMEYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHIKIADFGMCKEN
IWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAPFEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPG
KRLGCGPEGERDIKEHAFFRYIDWEKLERKEIQPPYKPKARDKRDTSNFDKEFTRQPVELTPTDKLFIMNLDQNEFAGFSYTNPEFVINV

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for C6orf106-PRKCB


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for C6orf106-PRKCB


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for C6orf106-PRKCB


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC0004352Autistic Disorder1CTD_human
TgeneC0009402Colorectal Carcinoma1CTD_human
TgeneC0009404Colorectal Neoplasms1CTD_human
TgeneC0011860Diabetes Mellitus, Non-Insulin-Dependent1CTD_human
TgeneC0018800Cardiomegaly1CTD_human
TgeneC0020456Hyperglycemia1CTD_human
TgeneC0023493Adult T-Cell Lymphoma/Leukemia1CTD_human
TgeneC0023893Liver Cirrhosis, Experimental1CTD_human
TgeneC0024623Malignant neoplasm of stomach1CTD_human
TgeneC0025281Meniere Disease1GENOMICS_ENGLAND
TgeneC0038356Stomach Neoplasms1CTD_human
TgeneC0041696Unipolar Depression1PSYGENET
TgeneC1269683Major Depressive Disorder1PSYGENET
TgeneC1383860Cardiac Hypertrophy1CTD_human
TgeneC1708349Hereditary Diffuse Gastric Cancer1CTD_human
TgeneC1855520Hyperglycemia, Postprandial1CTD_human