Fusion Gene Studies
in Kim Lab

FusionBase FusionGDB FusionGDB2 FusionPDB FusionNeoAntigen FusionAI FusionNW FGviewer Publication Contact
FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:CAAP1-TNNI3K (FusionGDB2 ID:HG79886TG51086)

Fusion Gene Summary for CAAP1-TNNI3K

check button Fusion gene summary
Fusion gene informationFusion gene name: CAAP1-TNNI3K
Fusion gene ID: hg79886tg51086
HgeneTgene
Gene symbol

CAAP1

TNNI3K

Gene ID

79886

51086

Gene namecaspase activity and apoptosis inhibitor 1TNNI3 interacting kinase
SynonymsC9orf82|CAAPCARK|CCDD
Cytomap('CAAP1')('TNNI3K')

9p21.2

1p31.1

Type of geneprotein-codingprotein-coding
Descriptioncaspase activity and apoptosis inhibitor 1conserved anti-apoptotic proteinserine/threonine-protein kinase TNNI3Kcardiac ankyrin repeat kinasecardiac troponin I-interacting kinase
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000333916, ENST00000535437, 
ENST00000495958, ENST00000520187, 
Fusion gene scores* DoF score5 X 4 X 5=1005 X 5 X 4=100
# samples 66
** MAII scorelog2(6/100*10)=-0.736965594166206
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(6/100*10)=-0.736965594166206
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CAAP1 [Title/Abstract] AND TNNI3K [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCAAP1(26861064)-TNNI3K(74832940), # samples:2
Anticipated loss of major functional domain due to fusion event.CAAP1-TNNI3K seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CAAP1-TNNI3K seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CAAP1-TNNI3K seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CAAP1-TNNI3K seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CAAP1-TNNI3K seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
CAAP1-TNNI3K seems lost the major protein functional domain in Tgene partner, which is a kinase due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneTNNI3K

GO:0006468

protein phosphorylation

12721663


check buttonFusion gene breakpoints across CAAP1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across TNNI3K (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-61-2095-01ACAAP1chr9

26861064

-TNNI3Kchr1

74832940

+
ChimerDB4OVTCGA-61-2095CAAP1chr9

26861063

-TNNI3Kchr1

74832939

+


Top

Fusion Gene ORF analysis for CAAP1-TNNI3K

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000333916ENST00000465473CAAP1chr9

26861064

-TNNI3Kchr1

74832940

+
5CDS-intronENST00000333916ENST00000465473CAAP1chr9

26861063

-TNNI3Kchr1

74832939

+
5CDS-intronENST00000535437ENST00000465473CAAP1chr9

26861064

-TNNI3Kchr1

74832940

+
5CDS-intronENST00000535437ENST00000465473CAAP1chr9

26861063

-TNNI3Kchr1

74832939

+
Frame-shiftENST00000535437ENST00000326637CAAP1chr9

26861064

-TNNI3Kchr1

74832940

+
Frame-shiftENST00000535437ENST00000326637CAAP1chr9

26861063

-TNNI3Kchr1

74832939

+
Frame-shiftENST00000535437ENST00000370891CAAP1chr9

26861064

-TNNI3Kchr1

74832940

+
Frame-shiftENST00000535437ENST00000370891CAAP1chr9

26861063

-TNNI3Kchr1

74832939

+
In-frameENST00000333916ENST00000326637CAAP1chr9

26861064

-TNNI3Kchr1

74832940

+
In-frameENST00000333916ENST00000326637CAAP1chr9

26861063

-TNNI3Kchr1

74832939

+
In-frameENST00000333916ENST00000370891CAAP1chr9

26861064

-TNNI3Kchr1

74832940

+
In-frameENST00000333916ENST00000370891CAAP1chr9

26861063

-TNNI3Kchr1

74832939

+
intron-3CDSENST00000495958ENST00000326637CAAP1chr9

26861064

-TNNI3Kchr1

74832940

+
intron-3CDSENST00000495958ENST00000326637CAAP1chr9

26861063

-TNNI3Kchr1

74832939

+
intron-3CDSENST00000495958ENST00000370891CAAP1chr9

26861064

-TNNI3Kchr1

74832940

+
intron-3CDSENST00000495958ENST00000370891CAAP1chr9

26861063

-TNNI3Kchr1

74832939

+
intron-3CDSENST00000520187ENST00000326637CAAP1chr9

26861064

-TNNI3Kchr1

74832940

+
intron-3CDSENST00000520187ENST00000326637CAAP1chr9

26861063

-TNNI3Kchr1

74832939

+
intron-3CDSENST00000520187ENST00000370891CAAP1chr9

26861064

-TNNI3Kchr1

74832940

+
intron-3CDSENST00000520187ENST00000370891CAAP1chr9

26861063

-TNNI3Kchr1

74832939

+
intron-intronENST00000495958ENST00000465473CAAP1chr9

26861064

-TNNI3Kchr1

74832940

+
intron-intronENST00000495958ENST00000465473CAAP1chr9

26861063

-TNNI3Kchr1

74832939

+
intron-intronENST00000520187ENST00000465473CAAP1chr9

26861064

-TNNI3Kchr1

74832940

+
intron-intronENST00000520187ENST00000465473CAAP1chr9

26861063

-TNNI3Kchr1

74832939

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000333916CAAP1chr926861064-ENST00000370891TNNI3Kchr174832940+2601828892158689
ENST00000333916CAAP1chr926861064-ENST00000326637TNNI3Kchr174832940+2601828892158689
ENST00000333916CAAP1chr926861063-ENST00000370891TNNI3Kchr174832939+2601828892158689
ENST00000333916CAAP1chr926861063-ENST00000326637TNNI3Kchr174832939+2601828892158689

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000333916ENST00000370891CAAP1chr926861064-TNNI3Kchr174832940+0.0043653910.9956346
ENST00000333916ENST00000326637CAAP1chr926861064-TNNI3Kchr174832940+0.0043653910.9956346
ENST00000333916ENST00000370891CAAP1chr926861063-TNNI3Kchr174832939+0.0043653910.9956346
ENST00000333916ENST00000326637CAAP1chr926861063-TNNI3Kchr174832939+0.0043653910.9956346

Top

Fusion Genomic Features for CAAP1-TNNI3K


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CAAP1chr926861063-TNNI3Kchr174832939+0.0014876020.9985123
CAAP1chr926861063-TNNI3Kchr174832939+0.0014876020.9985123
CAAP1chr926861063-TNNI3Kchr174832939+0.0014876020.9985123
CAAP1chr926861063-TNNI3Kchr174832939+0.0014876020.9985123

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for CAAP1-TNNI3K


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:26861064/chr1:74832940)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCAAP1chr9:26861063chr1:74832939ENST00000333916-5619_25246362.0Compositional biasNote=Poly-Ala
HgeneCAAP1chr9:26861063chr1:74832939ENST00000535437-5619_25101217.0Compositional biasNote=Poly-Ala
HgeneCAAP1chr9:26861064chr1:74832940ENST00000333916-5619_25246362.0Compositional biasNote=Poly-Ala
HgeneCAAP1chr9:26861064chr1:74832940ENST00000535437-5619_25101217.0Compositional biasNote=Poly-Ala
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003266371025733_746392836.0Compositional biasNote=Poly-Ser
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003708911227733_746493937.0Compositional biasNote=Poly-Ser
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003266371025733_746392836.0Compositional biasNote=Poly-Ser
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003708911227733_746493937.0Compositional biasNote=Poly-Ser
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003266371025463_723392836.0DomainProtein kinase
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003266371025463_723392836.0DomainProtein kinase
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003266371025469_477392836.0Nucleotide bindingATP
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003266371025469_477392836.0Nucleotide bindingATP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCAAP1chr9:26861063chr1:74832939ENST00000333916-56281_311246362.0Coiled coilOntology_term=ECO:0000255
HgeneCAAP1chr9:26861063chr1:74832939ENST00000535437-56281_311101217.0Coiled coilOntology_term=ECO:0000255
HgeneCAAP1chr9:26861064chr1:74832940ENST00000333916-56281_311246362.0Coiled coilOntology_term=ECO:0000255
HgeneCAAP1chr9:26861064chr1:74832940ENST00000535437-56281_311101217.0Coiled coilOntology_term=ECO:0000255
TgeneTNNI3Kchr9:26861063chr1:74832939ENST00000326637102521_51392836.0Coiled coilOntology_term=ECO:0000255
TgeneTNNI3Kchr9:26861063chr1:74832939ENST00000370891122721_51493937.0Coiled coilOntology_term=ECO:0000255
TgeneTNNI3Kchr9:26861064chr1:74832940ENST00000326637102521_51392836.0Coiled coilOntology_term=ECO:0000255
TgeneTNNI3Kchr9:26861064chr1:74832940ENST00000370891122721_51493937.0Coiled coilOntology_term=ECO:0000255
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003708911227463_723493937.0DomainProtein kinase
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003708911227463_723493937.0DomainProtein kinase
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003708911227469_477493937.0Nucleotide bindingATP
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003708911227469_477493937.0Nucleotide bindingATP
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003266371025100_129392836.0RepeatNote=ANK 2
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003266371025133_162392836.0RepeatNote=ANK 3
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003266371025166_195392836.0RepeatNote=ANK 4
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003266371025199_228392836.0RepeatNote=ANK 5
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003266371025234_263392836.0RepeatNote=ANK 6
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003266371025269_298392836.0RepeatNote=ANK 7
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003266371025304_335392836.0RepeatNote=ANK 8
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003266371025339_368392836.0RepeatNote=ANK 9
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003266371025381_410392836.0RepeatNote=ANK 10
TgeneTNNI3Kchr9:26861063chr1:74832939ENST00000326637102566_96392836.0RepeatNote=ANK 1
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003708911227100_129493937.0RepeatNote=ANK 2
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003708911227133_162493937.0RepeatNote=ANK 3
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003708911227166_195493937.0RepeatNote=ANK 4
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003708911227199_228493937.0RepeatNote=ANK 5
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003708911227234_263493937.0RepeatNote=ANK 6
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003708911227269_298493937.0RepeatNote=ANK 7
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003708911227304_335493937.0RepeatNote=ANK 8
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003708911227339_368493937.0RepeatNote=ANK 9
TgeneTNNI3Kchr9:26861063chr1:74832939ENST000003708911227381_410493937.0RepeatNote=ANK 10
TgeneTNNI3Kchr9:26861063chr1:74832939ENST00000370891122766_96493937.0RepeatNote=ANK 1
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003266371025100_129392836.0RepeatNote=ANK 2
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003266371025133_162392836.0RepeatNote=ANK 3
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003266371025166_195392836.0RepeatNote=ANK 4
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003266371025199_228392836.0RepeatNote=ANK 5
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003266371025234_263392836.0RepeatNote=ANK 6
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003266371025269_298392836.0RepeatNote=ANK 7
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003266371025304_335392836.0RepeatNote=ANK 8
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003266371025339_368392836.0RepeatNote=ANK 9
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003266371025381_410392836.0RepeatNote=ANK 10
TgeneTNNI3Kchr9:26861064chr1:74832940ENST00000326637102566_96392836.0RepeatNote=ANK 1
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003708911227100_129493937.0RepeatNote=ANK 2
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003708911227133_162493937.0RepeatNote=ANK 3
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003708911227166_195493937.0RepeatNote=ANK 4
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003708911227199_228493937.0RepeatNote=ANK 5
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003708911227234_263493937.0RepeatNote=ANK 6
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003708911227269_298493937.0RepeatNote=ANK 7
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003708911227304_335493937.0RepeatNote=ANK 8
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003708911227339_368493937.0RepeatNote=ANK 9
TgeneTNNI3Kchr9:26861064chr1:74832940ENST000003708911227381_410493937.0RepeatNote=ANK 10
TgeneTNNI3Kchr9:26861064chr1:74832940ENST00000370891122766_96493937.0RepeatNote=ANK 1


Top

Fusion Gene Sequence for CAAP1-TNNI3K


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>12205_12205_1_CAAP1-TNNI3K_CAAP1_chr9_26861063_ENST00000333916_TNNI3K_chr1_74832939_ENST00000326637_length(transcript)=2601nt_BP=828nt
CCAGTGCCTGCCGCCCACGGCCGCAGGAGTCGGGCTTCGGTCGCACCAGAGACAGCGGACTTTCCTCCGATGGTTGCAGCAGAGGGATCA
TGACGGGGAAAAAGTCCTCCCGGGAGAAACGGCGCAAACGTAGCAGTCAGGAGGCGGCCGCAGCGCTCGCGGCCCCGGACATCGTACCCG
CGTTGGCCAGCGGCAGCAGTGGAAGCACTAGCGGCTGCGGGAGCGCCGGGGGCTGCGGGAGCGTCAGCTGCTGTGGGAACGCCAATTTTA
GTGGAAGTGTCACCGGCGGTGGGAGCGGCGGCAGCTGTTGGGGCGGGAGCAGCGTGGAGCGCAGCGAGCGCCGGAAGCGGAGGAGTACCG
ACTCTTCCAGCGTCTCGGGCTCCTTGCAGCAGGAAACTAAATATATTTTGCCAACTTTGGAAAAAGAATTATTCTTGGCAGAGCACAGTG
ACCTTGAAGAAGGTGGACTGGACCTGACTGTGTCATTGAAACCAGTTAGTTTCTATATATCAGACAAAAAAGAAATGCTTCAGCAGTGCT
TCTGTATTATAGGAGAGAAAAAGTTACAGAAGATGCTTCCTGATGTGTTAAAGAACTGTTCAATAGAAGAAATTAAAAAACTATGCCAGG
AACAGTTAGAGCTCCTGTCTGAAAAAAAAATTTTGAAGATTCTTGAGGGTGACAATGGAATGGACTCTGATATGGAAGAGGAAGCAGATG
ATGGTTCTAAGATGGGATCTGATTTAGTCAGTCAGCAAGACATCTGTATAGATTCTGCTTCATCCGTGAGAGAGAATAAGCAACCTGAAG
GTTTGGAATTAAAACAAGGGCATGATGCCATTGTCACACTCCTGAAGCATTATAAGAGACCACAAGATGAATTGCCCTGTAATGAATATT
CTCAGCCTGGAGGAGATGGCTCCTATGTGTCTGTTCCATCACCCTTGGGGAAGATTAAAAGCATGACAAAAGAGAAGGCAGATATTCTCC
TCCTAAGAGCTGGATTGCCTTCACATTTCCATCTTCAGCTCTCAGAAATTGAGTTCCATGAGATTATTGGCTCAGGTTCTTTTGGGAAAG
TATATAAAGGACGATGCAGAAATAAAATAGTGGCTATAAAACGTTATCGAGCCAATACCTACTGCTCCAAGTCAGATGTGGATATGTTTT
GCCGAGAGGTGTCCATTCTCTGCCAGCTCAATCATCCCTGCGTAATTCAGTTTGTGGGTGCTTGCTTGAATGATCCCAGCCAGTTTGCCA
TTGTCACTCAATACATATCAGGGGGTTCTCTGTTCTCCCTCCTTCATGAGCAGAAGAGGATTCTTGATTTGCAGTCTAAATTAATTATTG
CAGTAGATGTTGCCAAAGGCATGGAGTACCTTCACAACCTGACACAGCCAATTATACATCGTGACTTGAACAGTCACAATATTCTTCTCT
ATGAGGATGGGCATGCTGTGGTGGCAGATTTTGGAGAATCAAGATTTCTACAGTCTCTGGATGAAGACAACATGACAAAACAACCTGGGA
ACCTCCGTTGGATGGCTCCTGAGGTGTTCACGCAGTGCACTCGGTACACCATCAAAGCAGATGTCTTCAGCTATGCTCTGTGTCTGTGGG
AAATTCTCACTGGCGAAATTCCATTCGCTCATCTCAAGCCAGCGGCTGCGGCAGCAGACATGGCTTACCACCACATCAGACCTCCCATTG
GCTATTCCATTCCCAAGCCCATATCATCTCTGCTGATACGAGGGTGGAACGCATGTCCTGAAGGAAGACCCGAATTTTCTGAAGTTGTCA
TGAAGTTAGAAGAGTGTCTCTGCAACATTGAGCTGATGTCTCCTGCATCAAGTAACAGCAGTGGGTCTCTCTCACCTTCTTCTTCTTCTG
ATTGCCTGGTGAACCGGGGAGGACCTGGCCGGAGTCATGTGGCAGCATTAAGAAGTCGTTTCGAATTGGAATATGCTCTAAATGCAAGGT
CCTATGCTGCTTTGTCCCAAAGTGCTGGACAATATTCCTCTCAAGGTCTGTCTTTGGAGGAGATGAAAAGAAGTCTTCAATACACACCCA
TTGACAAATATGGCTATGTATCCGATCCCATGAGCTCAATGCATTTTCATTCTTGCCGAAATAGTAGCAGCTTTGAGGACAGCAGCTGAC
AGCATTCGGCGTATACCTAAGGAGAGTTTTTTCCCCGAACTGACAGCAACGATTCCAACCACGGCAAGCTGGCTTCCAACTATAACATTT
TACTCTCAAAGGTCTCCTTAAATTGGGCTTGTTTTTACTTGTCCTATTTAATTCCCCACTATTAGCAGGCTTTGGATTTGTGCCTAAGGA
ATAATATGCAAAAGAACCAAGACAGAATGTATATGAAGAATTGTTTTTAATTTTGTAAATTAAAAAAAAATTTAGATCGTTACTTGGAAA
TGGAGCCTAAGTCTGTGGTGGACAGATAATAATTATGTTTTCCTGGGCTGAATTATGTAGACTTGTGTTTGACAGCTATGGGTTTATTTC

>12205_12205_1_CAAP1-TNNI3K_CAAP1_chr9_26861063_ENST00000333916_TNNI3K_chr1_74832939_ENST00000326637_length(amino acids)=689AA_BP=246
MTGKKSSREKRRKRSSQEAAAALAAPDIVPALASGSSGSTSGCGSAGGCGSVSCCGNANFSGSVTGGGSGGSCWGGSSVERSERRKRRST
DSSSVSGSLQQETKYILPTLEKELFLAEHSDLEEGGLDLTVSLKPVSFYISDKKEMLQQCFCIIGEKKLQKMLPDVLKNCSIEEIKKLCQ
EQLELLSEKKILKILEGDNGMDSDMEEEADDGSKMGSDLVSQQDICIDSASSVRENKQPEGLELKQGHDAIVTLLKHYKRPQDELPCNEY
SQPGGDGSYVSVPSPLGKIKSMTKEKADILLLRAGLPSHFHLQLSEIEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMF
CREVSILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSLFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHNLTQPIIHRDLNSHNILL
YEDGHAVVADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYALCLWEILTGEIPFAHLKPAAAAADMAYHHIRPPI
GYSIPKPISSLLIRGWNACPEGRPEFSEVVMKLEECLCNIELMSPASSNSSGSLSPSSSSDCLVNRGGPGRSHVAALRSRFELEYALNAR

--------------------------------------------------------------
>12205_12205_2_CAAP1-TNNI3K_CAAP1_chr9_26861063_ENST00000333916_TNNI3K_chr1_74832939_ENST00000370891_length(transcript)=2601nt_BP=828nt
CCAGTGCCTGCCGCCCACGGCCGCAGGAGTCGGGCTTCGGTCGCACCAGAGACAGCGGACTTTCCTCCGATGGTTGCAGCAGAGGGATCA
TGACGGGGAAAAAGTCCTCCCGGGAGAAACGGCGCAAACGTAGCAGTCAGGAGGCGGCCGCAGCGCTCGCGGCCCCGGACATCGTACCCG
CGTTGGCCAGCGGCAGCAGTGGAAGCACTAGCGGCTGCGGGAGCGCCGGGGGCTGCGGGAGCGTCAGCTGCTGTGGGAACGCCAATTTTA
GTGGAAGTGTCACCGGCGGTGGGAGCGGCGGCAGCTGTTGGGGCGGGAGCAGCGTGGAGCGCAGCGAGCGCCGGAAGCGGAGGAGTACCG
ACTCTTCCAGCGTCTCGGGCTCCTTGCAGCAGGAAACTAAATATATTTTGCCAACTTTGGAAAAAGAATTATTCTTGGCAGAGCACAGTG
ACCTTGAAGAAGGTGGACTGGACCTGACTGTGTCATTGAAACCAGTTAGTTTCTATATATCAGACAAAAAAGAAATGCTTCAGCAGTGCT
TCTGTATTATAGGAGAGAAAAAGTTACAGAAGATGCTTCCTGATGTGTTAAAGAACTGTTCAATAGAAGAAATTAAAAAACTATGCCAGG
AACAGTTAGAGCTCCTGTCTGAAAAAAAAATTTTGAAGATTCTTGAGGGTGACAATGGAATGGACTCTGATATGGAAGAGGAAGCAGATG
ATGGTTCTAAGATGGGATCTGATTTAGTCAGTCAGCAAGACATCTGTATAGATTCTGCTTCATCCGTGAGAGAGAATAAGCAACCTGAAG
GTTTGGAATTAAAACAAGGGCATGATGCCATTGTCACACTCCTGAAGCATTATAAGAGACCACAAGATGAATTGCCCTGTAATGAATATT
CTCAGCCTGGAGGAGATGGCTCCTATGTGTCTGTTCCATCACCCTTGGGGAAGATTAAAAGCATGACAAAAGAGAAGGCAGATATTCTCC
TCCTAAGAGCTGGATTGCCTTCACATTTCCATCTTCAGCTCTCAGAAATTGAGTTCCATGAGATTATTGGCTCAGGTTCTTTTGGGAAAG
TATATAAAGGACGATGCAGAAATAAAATAGTGGCTATAAAACGTTATCGAGCCAATACCTACTGCTCCAAGTCAGATGTGGATATGTTTT
GCCGAGAGGTGTCCATTCTCTGCCAGCTCAATCATCCCTGCGTAATTCAGTTTGTGGGTGCTTGCTTGAATGATCCCAGCCAGTTTGCCA
TTGTCACTCAATACATATCAGGGGGTTCTCTGTTCTCCCTCCTTCATGAGCAGAAGAGGATTCTTGATTTGCAGTCTAAATTAATTATTG
CAGTAGATGTTGCCAAAGGCATGGAGTACCTTCACAACCTGACACAGCCAATTATACATCGTGACTTGAACAGTCACAATATTCTTCTCT
ATGAGGATGGGCATGCTGTGGTGGCAGATTTTGGAGAATCAAGATTTCTACAGTCTCTGGATGAAGACAACATGACAAAACAACCTGGGA
ACCTCCGTTGGATGGCTCCTGAGGTGTTCACGCAGTGCACTCGGTACACCATCAAAGCAGATGTCTTCAGCTATGCTCTGTGTCTGTGGG
AAATTCTCACTGGCGAAATTCCATTCGCTCATCTCAAGCCAGCGGCTGCGGCAGCAGACATGGCTTACCACCACATCAGACCTCCCATTG
GCTATTCCATTCCCAAGCCCATATCATCTCTGCTGATACGAGGGTGGAACGCATGTCCTGAAGGAAGACCCGAATTTTCTGAAGTTGTCA
TGAAGTTAGAAGAGTGTCTCTGCAACATTGAGCTGATGTCTCCTGCATCAAGTAACAGCAGTGGGTCTCTCTCACCTTCTTCTTCTTCTG
ATTGCCTGGTGAACCGGGGAGGACCTGGCCGGAGTCATGTGGCAGCATTAAGAAGTCGTTTCGAATTGGAATATGCTCTAAATGCAAGGT
CCTATGCTGCTTTGTCCCAAAGTGCTGGACAATATTCCTCTCAAGGTCTGTCTTTGGAGGAGATGAAAAGAAGTCTTCAATACACACCCA
TTGACAAATATGGCTATGTATCCGATCCCATGAGCTCAATGCATTTTCATTCTTGCCGAAATAGTAGCAGCTTTGAGGACAGCAGCTGAC
AGCATTCGGCGTATACCTAAGGAGAGTTTTTTCCCCGAACTGACAGCAACGATTCCAACCACGGCAAGCTGGCTTCCAACTATAACATTT
TACTCTCAAAGGTCTCCTTAAATTGGGCTTGTTTTTACTTGTCCTATTTAATTCCCCACTATTAGCAGGCTTTGGATTTGTGCCTAAGGA
ATAATATGCAAAAGAACCAAGACAGAATGTATATGAAGAATTGTTTTTAATTTTGTAAATTAAAAAAAAATTTAGATCGTTACTTGGAAA
TGGAGCCTAAGTCTGTGGTGGACAGATAATAATTATGTTTTCCTGGGCTGAATTATGTAGACTTGTGTTTGACAGCTATGGGTTTATTTC

>12205_12205_2_CAAP1-TNNI3K_CAAP1_chr9_26861063_ENST00000333916_TNNI3K_chr1_74832939_ENST00000370891_length(amino acids)=689AA_BP=246
MTGKKSSREKRRKRSSQEAAAALAAPDIVPALASGSSGSTSGCGSAGGCGSVSCCGNANFSGSVTGGGSGGSCWGGSSVERSERRKRRST
DSSSVSGSLQQETKYILPTLEKELFLAEHSDLEEGGLDLTVSLKPVSFYISDKKEMLQQCFCIIGEKKLQKMLPDVLKNCSIEEIKKLCQ
EQLELLSEKKILKILEGDNGMDSDMEEEADDGSKMGSDLVSQQDICIDSASSVRENKQPEGLELKQGHDAIVTLLKHYKRPQDELPCNEY
SQPGGDGSYVSVPSPLGKIKSMTKEKADILLLRAGLPSHFHLQLSEIEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMF
CREVSILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSLFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHNLTQPIIHRDLNSHNILL
YEDGHAVVADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYALCLWEILTGEIPFAHLKPAAAAADMAYHHIRPPI
GYSIPKPISSLLIRGWNACPEGRPEFSEVVMKLEECLCNIELMSPASSNSSGSLSPSSSSDCLVNRGGPGRSHVAALRSRFELEYALNAR

--------------------------------------------------------------
>12205_12205_3_CAAP1-TNNI3K_CAAP1_chr9_26861064_ENST00000333916_TNNI3K_chr1_74832940_ENST00000326637_length(transcript)=2601nt_BP=828nt
CCAGTGCCTGCCGCCCACGGCCGCAGGAGTCGGGCTTCGGTCGCACCAGAGACAGCGGACTTTCCTCCGATGGTTGCAGCAGAGGGATCA
TGACGGGGAAAAAGTCCTCCCGGGAGAAACGGCGCAAACGTAGCAGTCAGGAGGCGGCCGCAGCGCTCGCGGCCCCGGACATCGTACCCG
CGTTGGCCAGCGGCAGCAGTGGAAGCACTAGCGGCTGCGGGAGCGCCGGGGGCTGCGGGAGCGTCAGCTGCTGTGGGAACGCCAATTTTA
GTGGAAGTGTCACCGGCGGTGGGAGCGGCGGCAGCTGTTGGGGCGGGAGCAGCGTGGAGCGCAGCGAGCGCCGGAAGCGGAGGAGTACCG
ACTCTTCCAGCGTCTCGGGCTCCTTGCAGCAGGAAACTAAATATATTTTGCCAACTTTGGAAAAAGAATTATTCTTGGCAGAGCACAGTG
ACCTTGAAGAAGGTGGACTGGACCTGACTGTGTCATTGAAACCAGTTAGTTTCTATATATCAGACAAAAAAGAAATGCTTCAGCAGTGCT
TCTGTATTATAGGAGAGAAAAAGTTACAGAAGATGCTTCCTGATGTGTTAAAGAACTGTTCAATAGAAGAAATTAAAAAACTATGCCAGG
AACAGTTAGAGCTCCTGTCTGAAAAAAAAATTTTGAAGATTCTTGAGGGTGACAATGGAATGGACTCTGATATGGAAGAGGAAGCAGATG
ATGGTTCTAAGATGGGATCTGATTTAGTCAGTCAGCAAGACATCTGTATAGATTCTGCTTCATCCGTGAGAGAGAATAAGCAACCTGAAG
GTTTGGAATTAAAACAAGGGCATGATGCCATTGTCACACTCCTGAAGCATTATAAGAGACCACAAGATGAATTGCCCTGTAATGAATATT
CTCAGCCTGGAGGAGATGGCTCCTATGTGTCTGTTCCATCACCCTTGGGGAAGATTAAAAGCATGACAAAAGAGAAGGCAGATATTCTCC
TCCTAAGAGCTGGATTGCCTTCACATTTCCATCTTCAGCTCTCAGAAATTGAGTTCCATGAGATTATTGGCTCAGGTTCTTTTGGGAAAG
TATATAAAGGACGATGCAGAAATAAAATAGTGGCTATAAAACGTTATCGAGCCAATACCTACTGCTCCAAGTCAGATGTGGATATGTTTT
GCCGAGAGGTGTCCATTCTCTGCCAGCTCAATCATCCCTGCGTAATTCAGTTTGTGGGTGCTTGCTTGAATGATCCCAGCCAGTTTGCCA
TTGTCACTCAATACATATCAGGGGGTTCTCTGTTCTCCCTCCTTCATGAGCAGAAGAGGATTCTTGATTTGCAGTCTAAATTAATTATTG
CAGTAGATGTTGCCAAAGGCATGGAGTACCTTCACAACCTGACACAGCCAATTATACATCGTGACTTGAACAGTCACAATATTCTTCTCT
ATGAGGATGGGCATGCTGTGGTGGCAGATTTTGGAGAATCAAGATTTCTACAGTCTCTGGATGAAGACAACATGACAAAACAACCTGGGA
ACCTCCGTTGGATGGCTCCTGAGGTGTTCACGCAGTGCACTCGGTACACCATCAAAGCAGATGTCTTCAGCTATGCTCTGTGTCTGTGGG
AAATTCTCACTGGCGAAATTCCATTCGCTCATCTCAAGCCAGCGGCTGCGGCAGCAGACATGGCTTACCACCACATCAGACCTCCCATTG
GCTATTCCATTCCCAAGCCCATATCATCTCTGCTGATACGAGGGTGGAACGCATGTCCTGAAGGAAGACCCGAATTTTCTGAAGTTGTCA
TGAAGTTAGAAGAGTGTCTCTGCAACATTGAGCTGATGTCTCCTGCATCAAGTAACAGCAGTGGGTCTCTCTCACCTTCTTCTTCTTCTG
ATTGCCTGGTGAACCGGGGAGGACCTGGCCGGAGTCATGTGGCAGCATTAAGAAGTCGTTTCGAATTGGAATATGCTCTAAATGCAAGGT
CCTATGCTGCTTTGTCCCAAAGTGCTGGACAATATTCCTCTCAAGGTCTGTCTTTGGAGGAGATGAAAAGAAGTCTTCAATACACACCCA
TTGACAAATATGGCTATGTATCCGATCCCATGAGCTCAATGCATTTTCATTCTTGCCGAAATAGTAGCAGCTTTGAGGACAGCAGCTGAC
AGCATTCGGCGTATACCTAAGGAGAGTTTTTTCCCCGAACTGACAGCAACGATTCCAACCACGGCAAGCTGGCTTCCAACTATAACATTT
TACTCTCAAAGGTCTCCTTAAATTGGGCTTGTTTTTACTTGTCCTATTTAATTCCCCACTATTAGCAGGCTTTGGATTTGTGCCTAAGGA
ATAATATGCAAAAGAACCAAGACAGAATGTATATGAAGAATTGTTTTTAATTTTGTAAATTAAAAAAAAATTTAGATCGTTACTTGGAAA
TGGAGCCTAAGTCTGTGGTGGACAGATAATAATTATGTTTTCCTGGGCTGAATTATGTAGACTTGTGTTTGACAGCTATGGGTTTATTTC

>12205_12205_3_CAAP1-TNNI3K_CAAP1_chr9_26861064_ENST00000333916_TNNI3K_chr1_74832940_ENST00000326637_length(amino acids)=689AA_BP=246
MTGKKSSREKRRKRSSQEAAAALAAPDIVPALASGSSGSTSGCGSAGGCGSVSCCGNANFSGSVTGGGSGGSCWGGSSVERSERRKRRST
DSSSVSGSLQQETKYILPTLEKELFLAEHSDLEEGGLDLTVSLKPVSFYISDKKEMLQQCFCIIGEKKLQKMLPDVLKNCSIEEIKKLCQ
EQLELLSEKKILKILEGDNGMDSDMEEEADDGSKMGSDLVSQQDICIDSASSVRENKQPEGLELKQGHDAIVTLLKHYKRPQDELPCNEY
SQPGGDGSYVSVPSPLGKIKSMTKEKADILLLRAGLPSHFHLQLSEIEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMF
CREVSILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSLFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHNLTQPIIHRDLNSHNILL
YEDGHAVVADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYALCLWEILTGEIPFAHLKPAAAAADMAYHHIRPPI
GYSIPKPISSLLIRGWNACPEGRPEFSEVVMKLEECLCNIELMSPASSNSSGSLSPSSSSDCLVNRGGPGRSHVAALRSRFELEYALNAR

--------------------------------------------------------------
>12205_12205_4_CAAP1-TNNI3K_CAAP1_chr9_26861064_ENST00000333916_TNNI3K_chr1_74832940_ENST00000370891_length(transcript)=2601nt_BP=828nt
CCAGTGCCTGCCGCCCACGGCCGCAGGAGTCGGGCTTCGGTCGCACCAGAGACAGCGGACTTTCCTCCGATGGTTGCAGCAGAGGGATCA
TGACGGGGAAAAAGTCCTCCCGGGAGAAACGGCGCAAACGTAGCAGTCAGGAGGCGGCCGCAGCGCTCGCGGCCCCGGACATCGTACCCG
CGTTGGCCAGCGGCAGCAGTGGAAGCACTAGCGGCTGCGGGAGCGCCGGGGGCTGCGGGAGCGTCAGCTGCTGTGGGAACGCCAATTTTA
GTGGAAGTGTCACCGGCGGTGGGAGCGGCGGCAGCTGTTGGGGCGGGAGCAGCGTGGAGCGCAGCGAGCGCCGGAAGCGGAGGAGTACCG
ACTCTTCCAGCGTCTCGGGCTCCTTGCAGCAGGAAACTAAATATATTTTGCCAACTTTGGAAAAAGAATTATTCTTGGCAGAGCACAGTG
ACCTTGAAGAAGGTGGACTGGACCTGACTGTGTCATTGAAACCAGTTAGTTTCTATATATCAGACAAAAAAGAAATGCTTCAGCAGTGCT
TCTGTATTATAGGAGAGAAAAAGTTACAGAAGATGCTTCCTGATGTGTTAAAGAACTGTTCAATAGAAGAAATTAAAAAACTATGCCAGG
AACAGTTAGAGCTCCTGTCTGAAAAAAAAATTTTGAAGATTCTTGAGGGTGACAATGGAATGGACTCTGATATGGAAGAGGAAGCAGATG
ATGGTTCTAAGATGGGATCTGATTTAGTCAGTCAGCAAGACATCTGTATAGATTCTGCTTCATCCGTGAGAGAGAATAAGCAACCTGAAG
GTTTGGAATTAAAACAAGGGCATGATGCCATTGTCACACTCCTGAAGCATTATAAGAGACCACAAGATGAATTGCCCTGTAATGAATATT
CTCAGCCTGGAGGAGATGGCTCCTATGTGTCTGTTCCATCACCCTTGGGGAAGATTAAAAGCATGACAAAAGAGAAGGCAGATATTCTCC
TCCTAAGAGCTGGATTGCCTTCACATTTCCATCTTCAGCTCTCAGAAATTGAGTTCCATGAGATTATTGGCTCAGGTTCTTTTGGGAAAG
TATATAAAGGACGATGCAGAAATAAAATAGTGGCTATAAAACGTTATCGAGCCAATACCTACTGCTCCAAGTCAGATGTGGATATGTTTT
GCCGAGAGGTGTCCATTCTCTGCCAGCTCAATCATCCCTGCGTAATTCAGTTTGTGGGTGCTTGCTTGAATGATCCCAGCCAGTTTGCCA
TTGTCACTCAATACATATCAGGGGGTTCTCTGTTCTCCCTCCTTCATGAGCAGAAGAGGATTCTTGATTTGCAGTCTAAATTAATTATTG
CAGTAGATGTTGCCAAAGGCATGGAGTACCTTCACAACCTGACACAGCCAATTATACATCGTGACTTGAACAGTCACAATATTCTTCTCT
ATGAGGATGGGCATGCTGTGGTGGCAGATTTTGGAGAATCAAGATTTCTACAGTCTCTGGATGAAGACAACATGACAAAACAACCTGGGA
ACCTCCGTTGGATGGCTCCTGAGGTGTTCACGCAGTGCACTCGGTACACCATCAAAGCAGATGTCTTCAGCTATGCTCTGTGTCTGTGGG
AAATTCTCACTGGCGAAATTCCATTCGCTCATCTCAAGCCAGCGGCTGCGGCAGCAGACATGGCTTACCACCACATCAGACCTCCCATTG
GCTATTCCATTCCCAAGCCCATATCATCTCTGCTGATACGAGGGTGGAACGCATGTCCTGAAGGAAGACCCGAATTTTCTGAAGTTGTCA
TGAAGTTAGAAGAGTGTCTCTGCAACATTGAGCTGATGTCTCCTGCATCAAGTAACAGCAGTGGGTCTCTCTCACCTTCTTCTTCTTCTG
ATTGCCTGGTGAACCGGGGAGGACCTGGCCGGAGTCATGTGGCAGCATTAAGAAGTCGTTTCGAATTGGAATATGCTCTAAATGCAAGGT
CCTATGCTGCTTTGTCCCAAAGTGCTGGACAATATTCCTCTCAAGGTCTGTCTTTGGAGGAGATGAAAAGAAGTCTTCAATACACACCCA
TTGACAAATATGGCTATGTATCCGATCCCATGAGCTCAATGCATTTTCATTCTTGCCGAAATAGTAGCAGCTTTGAGGACAGCAGCTGAC
AGCATTCGGCGTATACCTAAGGAGAGTTTTTTCCCCGAACTGACAGCAACGATTCCAACCACGGCAAGCTGGCTTCCAACTATAACATTT
TACTCTCAAAGGTCTCCTTAAATTGGGCTTGTTTTTACTTGTCCTATTTAATTCCCCACTATTAGCAGGCTTTGGATTTGTGCCTAAGGA
ATAATATGCAAAAGAACCAAGACAGAATGTATATGAAGAATTGTTTTTAATTTTGTAAATTAAAAAAAAATTTAGATCGTTACTTGGAAA
TGGAGCCTAAGTCTGTGGTGGACAGATAATAATTATGTTTTCCTGGGCTGAATTATGTAGACTTGTGTTTGACAGCTATGGGTTTATTTC

>12205_12205_4_CAAP1-TNNI3K_CAAP1_chr9_26861064_ENST00000333916_TNNI3K_chr1_74832940_ENST00000370891_length(amino acids)=689AA_BP=246
MTGKKSSREKRRKRSSQEAAAALAAPDIVPALASGSSGSTSGCGSAGGCGSVSCCGNANFSGSVTGGGSGGSCWGGSSVERSERRKRRST
DSSSVSGSLQQETKYILPTLEKELFLAEHSDLEEGGLDLTVSLKPVSFYISDKKEMLQQCFCIIGEKKLQKMLPDVLKNCSIEEIKKLCQ
EQLELLSEKKILKILEGDNGMDSDMEEEADDGSKMGSDLVSQQDICIDSASSVRENKQPEGLELKQGHDAIVTLLKHYKRPQDELPCNEY
SQPGGDGSYVSVPSPLGKIKSMTKEKADILLLRAGLPSHFHLQLSEIEFHEIIGSGSFGKVYKGRCRNKIVAIKRYRANTYCSKSDVDMF
CREVSILCQLNHPCVIQFVGACLNDPSQFAIVTQYISGGSLFSLLHEQKRILDLQSKLIIAVDVAKGMEYLHNLTQPIIHRDLNSHNILL
YEDGHAVVADFGESRFLQSLDEDNMTKQPGNLRWMAPEVFTQCTRYTIKADVFSYALCLWEILTGEIPFAHLKPAAAAADMAYHHIRPPI
GYSIPKPISSLLIRGWNACPEGRPEFSEVVMKLEECLCNIELMSPASSNSSGSLSPSSSSDCLVNRGGPGRSHVAALRSRFELEYALNAR

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for CAAP1-TNNI3K


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for CAAP1-TNNI3K


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for CAAP1-TNNI3K


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC4015285CARDIAC CONDUCTION DISEASE WITH OR WITHOUT DILATED CARDIOMYOPATHY2CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
TgeneC3495676Anorectal Malformations1GENOMICS_ENGLAND