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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CMIP-CDYL2 (FusionGDB2 ID:HG80790TG124359)

Fusion Gene Summary for CMIP-CDYL2

check button Fusion gene summary
Fusion gene informationFusion gene name: CMIP-CDYL2
Fusion gene ID: hg80790tg124359
HgeneTgene
Gene symbol

CMIP

CDYL2

Gene ID

80790

124359

Gene namec-Maf inducing proteinchromodomain Y like 2
SynonymsTCMIPPCCP1
Cytomap('CMIP')('CDYL2')

16q23.2-q23.3

16q23.2

Type of geneprotein-codingprotein-coding
DescriptionC-Maf-inducing proteintc-Mipchromodomain Y-like protein 2CDY-like 2chromodomain protein, Y-like 2prostate cancer candidate protein 1, PCCP1
Modification date2020031320200318
UniProtAcc.

Q8N8U2

Ensembl transtripts involved in fusion geneENST00000537098, ENST00000398040, 
ENST00000539778, ENST00000566513, 
Fusion gene scores* DoF score23 X 18 X 9=37269 X 9 X 3=243
# samples 2811
** MAII scorelog2(28/3726*10)=-3.73412894199667
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/243*10)=-1.14345279008112
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CMIP [Title/Abstract] AND CDYL2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCMIP(81479146)-CDYL2(80719026), # samples:2
Anticipated loss of major functional domain due to fusion event.CMIP-CDYL2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CMIP-CDYL2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CMIP-CDYL2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CMIP-CDYL2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across CMIP (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across CDYL2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-AN-A0FJ-01ACMIPchr16

81479146

-CDYL2chr16

80719026

-
ChimerDB4BRCATCGA-AN-A0FJ-01ACMIPchr16

81479146

+CDYL2chr16

80719026

-


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Fusion Gene ORF analysis for CMIP-CDYL2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000537098ENST00000562753CMIPchr16

81479146

+CDYL2chr16

80719026

-
In-frameENST00000537098ENST00000562812CMIPchr16

81479146

+CDYL2chr16

80719026

-
In-frameENST00000537098ENST00000563890CMIPchr16

81479146

+CDYL2chr16

80719026

-
In-frameENST00000537098ENST00000566173CMIPchr16

81479146

+CDYL2chr16

80719026

-
In-frameENST00000537098ENST00000570137CMIPchr16

81479146

+CDYL2chr16

80719026

-
intron-3CDSENST00000398040ENST00000562812CMIPchr16

81479146

+CDYL2chr16

80719026

-
intron-3CDSENST00000398040ENST00000563890CMIPchr16

81479146

+CDYL2chr16

80719026

-
intron-3CDSENST00000398040ENST00000566173CMIPchr16

81479146

+CDYL2chr16

80719026

-
intron-3CDSENST00000398040ENST00000570137CMIPchr16

81479146

+CDYL2chr16

80719026

-
intron-3CDSENST00000539778ENST00000562812CMIPchr16

81479146

+CDYL2chr16

80719026

-
intron-3CDSENST00000539778ENST00000563890CMIPchr16

81479146

+CDYL2chr16

80719026

-
intron-3CDSENST00000539778ENST00000566173CMIPchr16

81479146

+CDYL2chr16

80719026

-
intron-3CDSENST00000539778ENST00000570137CMIPchr16

81479146

+CDYL2chr16

80719026

-
intron-3CDSENST00000566513ENST00000562812CMIPchr16

81479146

+CDYL2chr16

80719026

-
intron-3CDSENST00000566513ENST00000563890CMIPchr16

81479146

+CDYL2chr16

80719026

-
intron-3CDSENST00000566513ENST00000566173CMIPchr16

81479146

+CDYL2chr16

80719026

-
intron-3CDSENST00000566513ENST00000570137CMIPchr16

81479146

+CDYL2chr16

80719026

-
intron-5UTRENST00000398040ENST00000562753CMIPchr16

81479146

+CDYL2chr16

80719026

-
intron-5UTRENST00000539778ENST00000562753CMIPchr16

81479146

+CDYL2chr16

80719026

-
intron-5UTRENST00000566513ENST00000562753CMIPchr16

81479146

+CDYL2chr16

80719026

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000537098CMIPchr1681479146+ENST00000570137CDYL2chr1680719026-8351372721868598
ENST00000537098CMIPchr1681479146+ENST00000562812CDYL2chr1680719026-2344372721871599
ENST00000537098CMIPchr1681479146+ENST00000566173CDYL2chr1680719026-2344372721871599
ENST00000537098CMIPchr1681479146+ENST00000563890CDYL2chr1680719026-2344372721871599

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000537098ENST00000570137CMIPchr1681479146+CDYL2chr1680719026-0.0006948850.9993051
ENST00000537098ENST00000562812CMIPchr1681479146+CDYL2chr1680719026-0.015250340.9847497
ENST00000537098ENST00000566173CMIPchr1681479146+CDYL2chr1680719026-0.015250340.9847497
ENST00000537098ENST00000563890CMIPchr1681479146+CDYL2chr1680719026-0.015250340.9847497

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Fusion Genomic Features for CMIP-CDYL2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for CMIP-CDYL2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:81479146/chr16:80719026)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.CDYL2

Q8N8U2

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneCDYL2chr16:81479146chr16:80719026ENST00000570137077_678507.0DomainChromo

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCMIPchr16:81479146chr16:80719026ENST00000398040+11954_1630621.0DomainNote=PH
HgeneCMIPchr16:81479146chr16:80719026ENST00000537098+12154_163100774.0DomainNote=PH
HgeneCMIPchr16:81479146chr16:80719026ENST00000539778+12154_1630680.0DomainNote=PH
HgeneCMIPchr16:81479146chr16:80719026ENST00000398040+119663_6860621.0RepeatNote=LRR 1
HgeneCMIPchr16:81479146chr16:80719026ENST00000398040+119687_7070621.0RepeatNote=LRR 2
HgeneCMIPchr16:81479146chr16:80719026ENST00000398040+119712_7320621.0RepeatNote=LRR 3
HgeneCMIPchr16:81479146chr16:80719026ENST00000398040+119736_7560621.0RepeatNote=LRR 4
HgeneCMIPchr16:81479146chr16:80719026ENST00000537098+121663_686100774.0RepeatNote=LRR 1
HgeneCMIPchr16:81479146chr16:80719026ENST00000537098+121687_707100774.0RepeatNote=LRR 2
HgeneCMIPchr16:81479146chr16:80719026ENST00000537098+121712_732100774.0RepeatNote=LRR 3
HgeneCMIPchr16:81479146chr16:80719026ENST00000537098+121736_756100774.0RepeatNote=LRR 4
HgeneCMIPchr16:81479146chr16:80719026ENST00000539778+121663_6860680.0RepeatNote=LRR 1
HgeneCMIPchr16:81479146chr16:80719026ENST00000539778+121687_7070680.0RepeatNote=LRR 2
HgeneCMIPchr16:81479146chr16:80719026ENST00000539778+121712_7320680.0RepeatNote=LRR 3
HgeneCMIPchr16:81479146chr16:80719026ENST00000539778+121736_7560680.0RepeatNote=LRR 4


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Fusion Gene Sequence for CMIP-CDYL2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>17521_17521_1_CMIP-CDYL2_CMIP_chr16_81479146_ENST00000537098_CDYL2_chr16_80719026_ENST00000562812_length(transcript)=2344nt_BP=372nt
GGGGGCCCCGCCGCCCCAGCAGCCCAGGACAGCCCCCTCTCCCCGCCCCCAGCCCCCTCCCCCGGCGCGGCCATGGATGTGACCAGCAGC
TCGGGCGGCGGCGGCGACCCCCGGCAGATCGAGGAGACCAAGCCGCTGCTGGGGGGCGACGTGTCGGCCCCCGAAGGCACGAAGATGGGC
GCCGTGCCCTGCCGCCGGGCTCTTCTGCTTTGCAACGGGATGAGGTACAAACTGCTGCAGGAGGGCGACATTCAGGTCTGTGTCATCCGG
CACCCGCGGACCTTTCTCAGCAAGATCCTCACCTCGAAATTCCTGAGGCGCTGGGAGCCGCACCACCTAACGCTGGCCGACAACAGCCTG
GCGTCCGCCACGGTTGAAAGGATTGTAGACAAGAGGAAGAACAAGAAAGGAAAATGGGAGTATCTTATCCGATGGAAAGGCTACGGGAGC
ACCGAGGACACGTGGGAGCCGGAGCACCACCTCTTGCACTGTGAGGAGTTTATTGATGAATTCAATGGGTTGCACATGTCCAAGGACAAG
AGGATCAAGTCAGGGAAGCAGTCCAGTACCTCCAAGCTGCTGCGTGACAGTCGAGGCCCGTCGGTTGAGAAACTGTCCCACAGACCTTCA
GATCCTGGAAAGAGCAAGGGGACCTCCCATAAACGGAAGCGAATTAACCCTCCCCTGGCCAAGCCAAAAAAAGGGTATTCAGGCAAGCCC
TCTTCAGGAGGTGACAGGGCCACCAAGACGGTGTCTTACAGGACTACCCCCAGTGGTTTGCAAATAATGCCCCTGAAAAAGTCTCAGAAC
GGGATGGAAAATGGGGACGCCGGCTCTGAGAAGGATGAGAGGCACTTTGGAAATGGGTCCCATCAGCCTGGCTTGGATTTGAATGATCAT
GTTGGAGAGCAAGATATGGGTGAATGTGACGTGAATCACGCTACACTGGCGGAGAACGGGCTCGGTGGCTCTGCTCTGACCAACGGGGGA
TTGAACCTGCACAGTCCAGTGAAGAGGAAGCTGGAAGCGGAGAAGGACTACGTCTTTGACAAAAGGCTCAGATACAGTGTCCGCCAGAAT
GAAAGCAACTGTCGGTTTCGAGACATCGTTGTGCGGAAGGAAGAAGGGTTCACGCACATCCTGCTGTCCAGTCAGACCTCGGATAACAAT
GCCCTGACACCTGAGATCATGAAAGAAGTCCGGCGAGCGCTCTGCAACGCAGCCACAGACGACAGCAAACTGCTGCTCCTCAGCGCAGTG
GGGAGCGTGTTCTGCAGCGGCCTGGATTATTCCTACCTAATTGGCCGGTTGTCCAGCGACCGGCGAAAGGAGAGCACTCGGATTGCAGAA
GCCATCAGGGACTTTGTGAAGGCCTTTATCCAGTTTAAGAAGCCTATCGTGGTGGCCATCAATGGGCCGGCCCTGGGCCTGGGTGCCTCC
ATCCTGCCCCTCTGTGACATCGTGTGGGCCAGTGAGAAGGCCTGGTTCCAGACGCCCTACGCCACCATCCGCCTCACGCCTGCTGGCTGC
TCCTCCTACACCTTCCCCCAGATCCTGGGCGTCGCGCTGGCCAATGAGATGCTGTTCTGTGGGCGGAAGCTCACCGCCCAGGAGGCCTGC
AGCAGGGGGCTGGTGTCGCAGGTCTTCTGGCCCACCACGTTCAGCCAGGAGGTCATGCTGCGGGTCAAGGAGATGGCATCCTGCAGTGCC
GTGGTGTTAGAGGAGTCCAAATGCCTCGTGCGGAGCTTCCTGAAATCAGTGCTGGAAGACGTGAACGAGAAGGAATGCCTCATGCTCAAG
CAGCTCTGGAGCTCCTCCAAAGGCCTTGACTCCCTTTTCAGCTACCTGCAGGACAAAATTTATGAAGTCTGAGGGGCCCCAGCTCACGGG
CCCCCAACTTCCAGCTCTGCCCTGTGTTTCGGAAACCAGAGCACAGTGTCTGCCCCGGCCAAGGAGTTTGTCAAGGTGTCTCTTTATACG
TAGGGTTGTGTCCATTTCCTCGTGTCCTTTGGTTGCTCCTCCTTGGTTTGATTTTGTGTAATGGATGGAAAACGCAGCATACTTGGCCTC
CCCCACCTCCCTGCCCTTCCTGGCCAGAGAGCTGTCCAAGGCTGTATCTTCCCAGGGCTCCGCCAAGCACCGCTGTCCTTTCCCCACTTG
CTGAAATGCACCATGACGGTCCAGGAAGGGGAAGACCACTTTCACATTCTTCTGACTCAGGCTGTGTCTACACAGTGCCTCTGACTTGGA
GACTTGGCCATCATGGCTCTCTCTGGTTGTATTTAGATCGGGTGTCAGAGGACGACCAATCTTAGGGAATTTCCAGACCAATGAGCAAAA
TGAT

>17521_17521_1_CMIP-CDYL2_CMIP_chr16_81479146_ENST00000537098_CDYL2_chr16_80719026_ENST00000562812_length(amino acids)=599AA_BP=95
MDVTSSSGGGGDPRQIEETKPLLGGDVSAPEGTKMGAVPCRRALLLCNGMRYKLLQEGDIQVCVIRHPRTFLSKILTSKFLRRWEPHHLT
LADNSLASATVERIVDKRKNKKGKWEYLIRWKGYGSTEDTWEPEHHLLHCEEFIDEFNGLHMSKDKRIKSGKQSSTSKLLRDSRGPSVEK
LSHRPSDPGKSKGTSHKRKRINPPLAKPKKGYSGKPSSGGDRATKTVSYRTTPSGLQIMPLKKSQNGMENGDAGSEKDERHFGNGSHQPG
LDLNDHVGEQDMGECDVNHATLAENGLGGSALTNGGLNLHSPVKRKLEAEKDYVFDKRLRYSVRQNESNCRFRDIVVRKEEGFTHILLSS
QTSDNNALTPEIMKEVRRALCNAATDDSKLLLLSAVGSVFCSGLDYSYLIGRLSSDRRKESTRIAEAIRDFVKAFIQFKKPIVVAINGPA
LGLGASILPLCDIVWASEKAWFQTPYATIRLTPAGCSSYTFPQILGVALANEMLFCGRKLTAQEACSRGLVSQVFWPTTFSQEVMLRVKE
MASCSAVVLEESKCLVRSFLKSVLEDVNEKECLMLKQLWSSSKGLDSLFSYLQDKIYEV

--------------------------------------------------------------
>17521_17521_2_CMIP-CDYL2_CMIP_chr16_81479146_ENST00000537098_CDYL2_chr16_80719026_ENST00000563890_length(transcript)=2344nt_BP=372nt
GGGGGCCCCGCCGCCCCAGCAGCCCAGGACAGCCCCCTCTCCCCGCCCCCAGCCCCCTCCCCCGGCGCGGCCATGGATGTGACCAGCAGC
TCGGGCGGCGGCGGCGACCCCCGGCAGATCGAGGAGACCAAGCCGCTGCTGGGGGGCGACGTGTCGGCCCCCGAAGGCACGAAGATGGGC
GCCGTGCCCTGCCGCCGGGCTCTTCTGCTTTGCAACGGGATGAGGTACAAACTGCTGCAGGAGGGCGACATTCAGGTCTGTGTCATCCGG
CACCCGCGGACCTTTCTCAGCAAGATCCTCACCTCGAAATTCCTGAGGCGCTGGGAGCCGCACCACCTAACGCTGGCCGACAACAGCCTG
GCGTCCGCCACGGTTGAAAGGATTGTAGACAAGAGGAAGAACAAGAAAGGAAAATGGGAGTATCTTATCCGATGGAAAGGCTACGGGAGC
ACCGAGGACACGTGGGAGCCGGAGCACCACCTCTTGCACTGTGAGGAGTTTATTGATGAATTCAATGGGTTGCACATGTCCAAGGACAAG
AGGATCAAGTCAGGGAAGCAGTCCAGTACCTCCAAGCTGCTGCGTGACAGTCGAGGCCCGTCGGTTGAGAAACTGTCCCACAGACCTTCA
GATCCTGGAAAGAGCAAGGGGACCTCCCATAAACGGAAGCGAATTAACCCTCCCCTGGCCAAGCCAAAAAAAGGGTATTCAGGCAAGCCC
TCTTCAGGAGGTGACAGGGCCACCAAGACGGTGTCTTACAGGACTACCCCCAGTGGTTTGCAAATAATGCCCCTGAAAAAGTCTCAGAAC
GGGATGGAAAATGGGGACGCCGGCTCTGAGAAGGATGAGAGGCACTTTGGAAATGGGTCCCATCAGCCTGGCTTGGATTTGAATGATCAT
GTTGGAGAGCAAGATATGGGTGAATGTGACGTGAATCACGCTACACTGGCGGAGAACGGGCTCGGTGGCTCTGCTCTGACCAACGGGGGA
TTGAACCTGCACAGTCCAGTGAAGAGGAAGCTGGAAGCGGAGAAGGACTACGTCTTTGACAAAAGGCTCAGATACAGTGTCCGCCAGAAT
GAAAGCAACTGTCGGTTTCGAGACATCGTTGTGCGGAAGGAAGAAGGGTTCACGCACATCCTGCTGTCCAGTCAGACCTCGGATAACAAT
GCCCTGACACCTGAGATCATGAAAGAAGTCCGGCGAGCGCTCTGCAACGCAGCCACAGACGACAGCAAACTGCTGCTCCTCAGCGCAGTG
GGGAGCGTGTTCTGCAGCGGCCTGGATTATTCCTACCTAATTGGCCGGTTGTCCAGCGACCGGCGAAAGGAGAGCACTCGGATTGCAGAA
GCCATCAGGGACTTTGTGAAGGCCTTTATCCAGTTTAAGAAGCCTATCGTGGTGGCCATCAATGGGCCGGCCCTGGGCCTGGGTGCCTCC
ATCCTGCCCCTCTGTGACATCGTGTGGGCCAGTGAGAAGGCCTGGTTCCAGACGCCCTACGCCACCATCCGCCTCACGCCTGCTGGCTGC
TCCTCCTACACCTTCCCCCAGATCCTGGGCGTCGCGCTGGCCAATGAGATGCTGTTCTGTGGGCGGAAGCTCACCGCCCAGGAGGCCTGC
AGCAGGGGGCTGGTGTCGCAGGTCTTCTGGCCCACCACGTTCAGCCAGGAGGTCATGCTGCGGGTCAAGGAGATGGCATCCTGCAGTGCC
GTGGTGTTAGAGGAGTCCAAATGCCTCGTGCGGAGCTTCCTGAAATCAGTGCTGGAAGACGTGAACGAGAAGGAATGCCTCATGCTCAAG
CAGCTCTGGAGCTCCTCCAAAGGCCTTGACTCCCTTTTCAGCTACCTGCAGGACAAAATTTATGAAGTCTGAGGGGCCCCAGCTCACGGG
CCCCCAACTTCCAGCTCTGCCCTGTGTTTCGGAAACCAGAGCACAGTGTCTGCCCCGGCCAAGGAGTTTGTCAAGGTGTCTCTTTATACG
TAGGGTTGTGTCCATTTCCTCGTGTCCTTTGGTTGCTCCTCCTTGGTTTGATTTTGTGTAATGGATGGAAAACGCAGCATACTTGGCCTC
CCCCACCTCCCTGCCCTTCCTGGCCAGAGAGCTGTCCAAGGCTGTATCTTCCCAGGGCTCCGCCAAGCACCGCTGTCCTTTCCCCACTTG
CTGAAATGCACCATGACGGTCCAGGAAGGGGAAGACCACTTTCACATTCTTCTGACTCAGGCTGTGTCTACACAGTGCCTCTGACTTGGA
GACTTGGCCATCATGGCTCTCTCTGGTTGTATTTAGATCGGGTGTCAGAGGACGACCAATCTTAGGGAATTTCCAGACCAATGAGCAAAA
TGAT

>17521_17521_2_CMIP-CDYL2_CMIP_chr16_81479146_ENST00000537098_CDYL2_chr16_80719026_ENST00000563890_length(amino acids)=599AA_BP=95
MDVTSSSGGGGDPRQIEETKPLLGGDVSAPEGTKMGAVPCRRALLLCNGMRYKLLQEGDIQVCVIRHPRTFLSKILTSKFLRRWEPHHLT
LADNSLASATVERIVDKRKNKKGKWEYLIRWKGYGSTEDTWEPEHHLLHCEEFIDEFNGLHMSKDKRIKSGKQSSTSKLLRDSRGPSVEK
LSHRPSDPGKSKGTSHKRKRINPPLAKPKKGYSGKPSSGGDRATKTVSYRTTPSGLQIMPLKKSQNGMENGDAGSEKDERHFGNGSHQPG
LDLNDHVGEQDMGECDVNHATLAENGLGGSALTNGGLNLHSPVKRKLEAEKDYVFDKRLRYSVRQNESNCRFRDIVVRKEEGFTHILLSS
QTSDNNALTPEIMKEVRRALCNAATDDSKLLLLSAVGSVFCSGLDYSYLIGRLSSDRRKESTRIAEAIRDFVKAFIQFKKPIVVAINGPA
LGLGASILPLCDIVWASEKAWFQTPYATIRLTPAGCSSYTFPQILGVALANEMLFCGRKLTAQEACSRGLVSQVFWPTTFSQEVMLRVKE
MASCSAVVLEESKCLVRSFLKSVLEDVNEKECLMLKQLWSSSKGLDSLFSYLQDKIYEV

--------------------------------------------------------------
>17521_17521_3_CMIP-CDYL2_CMIP_chr16_81479146_ENST00000537098_CDYL2_chr16_80719026_ENST00000566173_length(transcript)=2344nt_BP=372nt
GGGGGCCCCGCCGCCCCAGCAGCCCAGGACAGCCCCCTCTCCCCGCCCCCAGCCCCCTCCCCCGGCGCGGCCATGGATGTGACCAGCAGC
TCGGGCGGCGGCGGCGACCCCCGGCAGATCGAGGAGACCAAGCCGCTGCTGGGGGGCGACGTGTCGGCCCCCGAAGGCACGAAGATGGGC
GCCGTGCCCTGCCGCCGGGCTCTTCTGCTTTGCAACGGGATGAGGTACAAACTGCTGCAGGAGGGCGACATTCAGGTCTGTGTCATCCGG
CACCCGCGGACCTTTCTCAGCAAGATCCTCACCTCGAAATTCCTGAGGCGCTGGGAGCCGCACCACCTAACGCTGGCCGACAACAGCCTG
GCGTCCGCCACGGTTGAAAGGATTGTAGACAAGAGGAAGAACAAGAAAGGAAAATGGGAGTATCTTATCCGATGGAAAGGCTACGGGAGC
ACCGAGGACACGTGGGAGCCGGAGCACCACCTCTTGCACTGTGAGGAGTTTATTGATGAATTCAATGGGTTGCACATGTCCAAGGACAAG
AGGATCAAGTCAGGGAAGCAGTCCAGTACCTCCAAGCTGCTGCGTGACAGTCGAGGCCCGTCGGTTGAGAAACTGTCCCACAGACCTTCA
GATCCTGGAAAGAGCAAGGGGACCTCCCATAAACGGAAGCGAATTAACCCTCCCCTGGCCAAGCCAAAAAAAGGGTATTCAGGCAAGCCC
TCTTCAGGAGGTGACAGGGCCACCAAGACGGTGTCTTACAGGACTACCCCCAGTGGTTTGCAAATAATGCCCCTGAAAAAGTCTCAGAAC
GGGATGGAAAATGGGGACGCCGGCTCTGAGAAGGATGAGAGGCACTTTGGAAATGGGTCCCATCAGCCTGGCTTGGATTTGAATGATCAT
GTTGGAGAGCAAGATATGGGTGAATGTGACGTGAATCACGCTACACTGGCGGAGAACGGGCTCGGTGGCTCTGCTCTGACCAACGGGGGA
TTGAACCTGCACAGTCCAGTGAAGAGGAAGCTGGAAGCGGAGAAGGACTACGTCTTTGACAAAAGGCTCAGATACAGTGTCCGCCAGAAT
GAAAGCAACTGTCGGTTTCGAGACATCGTTGTGCGGAAGGAAGAAGGGTTCACGCACATCCTGCTGTCCAGTCAGACCTCGGATAACAAT
GCCCTGACACCTGAGATCATGAAAGAAGTCCGGCGAGCGCTCTGCAACGCAGCCACAGACGACAGCAAACTGCTGCTCCTCAGCGCAGTG
GGGAGCGTGTTCTGCAGCGGCCTGGATTATTCCTACCTAATTGGCCGGTTGTCCAGCGACCGGCGAAAGGAGAGCACTCGGATTGCAGAA
GCCATCAGGGACTTTGTGAAGGCCTTTATCCAGTTTAAGAAGCCTATCGTGGTGGCCATCAATGGGCCGGCCCTGGGCCTGGGTGCCTCC
ATCCTGCCCCTCTGTGACATCGTGTGGGCCAGTGAGAAGGCCTGGTTCCAGACGCCCTACGCCACCATCCGCCTCACGCCTGCTGGCTGC
TCCTCCTACACCTTCCCCCAGATCCTGGGCGTCGCGCTGGCCAATGAGATGCTGTTCTGTGGGCGGAAGCTCACCGCCCAGGAGGCCTGC
AGCAGGGGGCTGGTGTCGCAGGTCTTCTGGCCCACCACGTTCAGCCAGGAGGTCATGCTGCGGGTCAAGGAGATGGCATCCTGCAGTGCC
GTGGTGTTAGAGGAGTCCAAATGCCTCGTGCGGAGCTTCCTGAAATCAGTGCTGGAAGACGTGAACGAGAAGGAATGCCTCATGCTCAAG
CAGCTCTGGAGCTCCTCCAAAGGCCTTGACTCCCTTTTCAGCTACCTGCAGGACAAAATTTATGAAGTCTGAGGGGCCCCAGCTCACGGG
CCCCCAACTTCCAGCTCTGCCCTGTGTTTCGGAAACCAGAGCACAGTGTCTGCCCCGGCCAAGGAGTTTGTCAAGGTGTCTCTTTATACG
TAGGGTTGTGTCCATTTCCTCGTGTCCTTTGGTTGCTCCTCCTTGGTTTGATTTTGTGTAATGGATGGAAAACGCAGCATACTTGGCCTC
CCCCACCTCCCTGCCCTTCCTGGCCAGAGAGCTGTCCAAGGCTGTATCTTCCCAGGGCTCCGCCAAGCACCGCTGTCCTTTCCCCACTTG
CTGAAATGCACCATGACGGTCCAGGAAGGGGAAGACCACTTTCACATTCTTCTGACTCAGGCTGTGTCTACACAGTGCCTCTGACTTGGA
GACTTGGCCATCATGGCTCTCTCTGGTTGTATTTAGATCGGGTGTCAGAGGACGACCAATCTTAGGGAATTTCCAGACCAATGAGCAAAA
TGAT

>17521_17521_3_CMIP-CDYL2_CMIP_chr16_81479146_ENST00000537098_CDYL2_chr16_80719026_ENST00000566173_length(amino acids)=599AA_BP=95
MDVTSSSGGGGDPRQIEETKPLLGGDVSAPEGTKMGAVPCRRALLLCNGMRYKLLQEGDIQVCVIRHPRTFLSKILTSKFLRRWEPHHLT
LADNSLASATVERIVDKRKNKKGKWEYLIRWKGYGSTEDTWEPEHHLLHCEEFIDEFNGLHMSKDKRIKSGKQSSTSKLLRDSRGPSVEK
LSHRPSDPGKSKGTSHKRKRINPPLAKPKKGYSGKPSSGGDRATKTVSYRTTPSGLQIMPLKKSQNGMENGDAGSEKDERHFGNGSHQPG
LDLNDHVGEQDMGECDVNHATLAENGLGGSALTNGGLNLHSPVKRKLEAEKDYVFDKRLRYSVRQNESNCRFRDIVVRKEEGFTHILLSS
QTSDNNALTPEIMKEVRRALCNAATDDSKLLLLSAVGSVFCSGLDYSYLIGRLSSDRRKESTRIAEAIRDFVKAFIQFKKPIVVAINGPA
LGLGASILPLCDIVWASEKAWFQTPYATIRLTPAGCSSYTFPQILGVALANEMLFCGRKLTAQEACSRGLVSQVFWPTTFSQEVMLRVKE
MASCSAVVLEESKCLVRSFLKSVLEDVNEKECLMLKQLWSSSKGLDSLFSYLQDKIYEV

--------------------------------------------------------------
>17521_17521_4_CMIP-CDYL2_CMIP_chr16_81479146_ENST00000537098_CDYL2_chr16_80719026_ENST00000570137_length(transcript)=8351nt_BP=372nt
GGGGGCCCCGCCGCCCCAGCAGCCCAGGACAGCCCCCTCTCCCCGCCCCCAGCCCCCTCCCCCGGCGCGGCCATGGATGTGACCAGCAGC
TCGGGCGGCGGCGGCGACCCCCGGCAGATCGAGGAGACCAAGCCGCTGCTGGGGGGCGACGTGTCGGCCCCCGAAGGCACGAAGATGGGC
GCCGTGCCCTGCCGCCGGGCTCTTCTGCTTTGCAACGGGATGAGGTACAAACTGCTGCAGGAGGGCGACATTCAGGTCTGTGTCATCCGG
CACCCGCGGACCTTTCTCAGCAAGATCCTCACCTCGAAATTCCTGAGGCGCTGGGAGCCGCACCACCTAACGCTGGCCGACAACAGCCTG
GCGTCCGCCACGGTTGAAAGGATTGTAGACAAGAGGAAGAACAAGAAAGGAAAATGGGAGTATCTTATCCGATGGAAAGGCTACGGGAGC
ACCGAGGACACGTGGGAGCCGGAGCACCACCTCTTGCACTGTGAGGAGTTTATTGATGAATTCAATGGGTTGCACATGTCCAAGGACAAG
AGGATCAAGTCAGGGAAGCAGTCCAGTACCTCCAAGCTGCTGCGTGACAGTCGAGGCCCGTCGGTTGAGAAACTGTCCCACAGACCTTCA
GATCCTGGAAAGAGCAAGGGGACCTCCCATAAACGGAAGCGAATTAACCCTCCCCTGGCCAAGCCAAAAAAAGGGTATTCAGGCAAGCCC
TCTTCAGGAGGTGACAGGGCCACCAAGACGGTGTCTTACAGGACTACCCCCAGTGGTTTGCAAATAATGCCCCTGAAAAAGTCTCAGAAC
GGGATGGAAAATGGGGACGCCGGCTCTGAGAAGGATGAGAGGCACTTTGGAAATGGGTCCCATCAGCCTGGCTTGGATTTGAATGATCAT
GTTGGAGAGCAAGATATGGGTGAATGTGACGTGAATCACGCTACACTGGCGGAGAACGGGCTCGGCTCTGCTCTGACCAACGGGGGATTG
AACCTGCACAGTCCAGTGAAGAGGAAGCTGGAAGCGGAGAAGGACTACGTCTTTGACAAAAGGCTCAGATACAGTGTCCGCCAGAATGAA
AGCAACTGTCGGTTTCGAGACATCGTTGTGCGGAAGGAAGAAGGGTTCACGCACATCCTGCTGTCCAGTCAGACCTCGGATAACAATGCC
CTGACACCTGAGATCATGAAAGAAGTCCGGCGAGCGCTCTGCAACGCAGCCACAGACGACAGCAAACTGCTGCTCCTCAGCGCAGTGGGG
AGCGTGTTCTGCAGCGGCCTGGATTATTCCTACCTAATTGGCCGGTTGTCCAGCGACCGGCGAAAGGAGAGCACTCGGATTGCAGAAGCC
ATCAGGGACTTTGTGAAGGCCTTTATCCAGTTTAAGAAGCCTATCGTGGTGGCCATCAATGGGCCGGCCCTGGGCCTGGGTGCCTCCATC
CTGCCCCTCTGTGACATCGTGTGGGCCAGTGAGAAGGCCTGGTTCCAGACGCCCTACGCCACCATCCGCCTCACGCCTGCTGGCTGCTCC
TCCTACACCTTCCCCCAGATCCTGGGCGTCGCGCTGGCCAATGAGATGCTGTTCTGTGGGCGGAAGCTCACCGCCCAGGAGGCCTGCAGC
AGGGGGCTGGTGTCGCAGGTCTTCTGGCCCACCACGTTCAGCCAGGAGGTCATGCTGCGGGTCAAGGAGATGGCATCCTGCAGTGCCGTG
GTGTTAGAGGAGTCCAAATGCCTCGTGCGGAGCTTCCTGAAATCAGTGCTGGAAGACGTGAACGAGAAGGAATGCCTCATGCTCAAGCAG
CTCTGGAGCTCCTCCAAAGGCCTTGACTCCCTTTTCAGCTACCTGCAGGACAAAATTTATGAAGTCTGAGGGGCCCCAGCTCACGGGCCC
CCAACTTCCAGCTCTGCCCTGTGTTTCGGAAACCAGAGCACAGTGTCTGCCCCGGCCAAGGAGTTTGTCAAGGTGTCTCTTTATACGTAG
GGTTGTGTCCATTTCCTCGTGTCCTTTGGTTGCTCCTCCTTGGTTTGATTTTGTGTAATGGATGGAAAACGCAGCATACTTGGCCTCCCC
CACCTCCCTGCCCTTCCTGGCCAGAGAGCTGTCCAAGGCTGTATCTTCCCAGGGCTCCGCCAAGCACCGCTGTCCTTTCCCCACTTGCTG
AAATGCACCATGACGGTCCAGGAAGGGGAAGACCACTTTCACATTCTTCTGACTCAGGCTGTGTCTACACAGTGCCTCTGACTTGGAGAC
TTGGCCATCATGGCTCTCTCTGGTTGTATTTAGATCGGGTGTCAGAGGACGACCAATCTTAGGGAATTTCCAGACCAATGAGCAAAATGA
TTGTGCACACCTGGCCTCAGTCTCCTTTCCGACGCAAATCTGTGTGACTATTAGGGCTTGGTCTTAAAACCCAATTGAGTGATTTGCAAA
CCCAGATATTGTACATTTAGAAATGTTTTGTTAAATATATATTTTTAAAACAATGTAAGTGGAAATTCTGATAATTTATGTGTATTATAT
GTAAAGCTAGTTTTGCAAAAACAAACTACTAGGGAAATGTTTTTTCTTTCCTTGGACTTGTTTTATTTATTTATTTTTGTTTATATATTG
TGATGTCTGTTGTTCACACAGATACTATTTTCATACTACCCTGGACCAAATCCCACACAAGGTTCATGCCGTTTGGTGCATTCTAGCAAT
GAACCATGTAGAAATAAAGTTTAGAGAGATGAAAACAGAAGGATTTCTGTGGACAAAAGGAATAGCGCTGCACCTCTGTGTAAAACGGTT
CTCAGCTGTAATAATAGAATACTAGTTCCTTAGGTTTGTCCTTAGGAGACATCTTGGGAGAGTTTTTTCTTCCCTCTGCTGTCTTTAAGG
AGTTAAAGGGCCCTCTTAGCCTGAATGATCCTGAAACAGACCCAGTCCCAAATTGCGTGATGTTGGGCAGGAGTGGGGATAGGCCCTACC
TGAGAATAGCATACTGTCTAGAATAAGACTTCTTTCTTTGGGGCAAATGACTGAACTTGGATCCTGCAGTCTGTTGCTTCCATGTGATCA
GTGATTTCTGGTATTGGCCAGGGGGATGGGGAAGAGTTCCCACTCTGCTGAGCTGTCTGGAGGTCTGAATCTTTTCCCTCCAGAAGCTGA
AATGACTCATCTGTTTTCTAGTTTTTTTATGTACATAGGGAGCAATGACCAGGAATGAGATCTCCTTGCCCCTGTGCCCCTGGGCTGCAA
GGGGACTCCAGCAGCTGTGTTAGACCATCAGATTCAAGTCCCTGGATTAACTACAGAGAAGGAGGGATTGGGGGTTGTGGTTTTGAGTGG
TGAGGAGAAAGTTCAGGAAAACCTGAAGTTGAGAGCAGACAAATGGAAGGGATGTGTTCTGCGTGAGGTTTAAACCATGGGTCAAGCACC
CAGAAAAAGCTAGATTCTCAGATTCTCAGGATGGAGGGATTTTTTTCCGTTTCTATCACAGCCCCTGCGTATTCCTGGAGGCCCTTGGCC
CTCCCCTTCTTCCCCTTTCCTGTTGGGCACCAGCCTTTCTTGGCCCTTCTTTGAAGAGAGTGGAATAAGGCAGCAAGAAGTGGGCACAGC
TTATGGAGGTGAGGCAGGCTTAGAAGAGAGAGTTCTGGTGACAGTTCTCTAACTCTCTGTGGTCCTTTATCTTTTCCTGGCAATCAGGTG
CACTGGGCAGGGCAGGTGGAATGTATTCGTGGCCCTGAGCTTTGAGTTTCAAAGAACACGTTGATAGTCTACACCAGATCTAGAGACATG
GTCCTTTAAGCAGTGACCCTCAAGTTAATCTGGACTGCTGGTCCTTCTGATGACCTTGGTTCCCTCCCTGGAAAGCGTGTCTCCTTTAAG
AGTTCATGAGGGTCAGGAAGGAGGGGAAACCTCTCCTTCAGCCAGAGGAGGATGGAATTAAAGTCCTGTGCACCCTCCCCTTTGTCCATG
TAGGATCCTGTAAGGACTTCGGACCTGTCCTACAGGGAGTTACTATAGGGAGACACCTGCTTTTGCCCAAATGCCTGTTGTCACAGCTCT
ATCTGGATCTTATCTCCTCCTTTGAGAAAGCAAATGTGAGCTTTCCAAAACCCTTAGATGACCCTGGTTCTTACATATTGTGGCAGACAG
TGTCTTCACTACTGCTAAATTTTCATTAGAAAGAGCCCCCTCTTTTCTGTTGAACTTCTGATTGGGCGCAGTTATATTCAGCATCGGTTG
AAGTGGGGTCAGGATTCTCCTTGGACATGGAAGGGGATGTTTAGAAATTCCTTTAGATCAGTGTCCACCTTCATTCCCTGCTTGAAAGAA
CTAGAAATGCTTCAGCTTTGGATGTACTATCAAATCCAAACTTCTAAACATTTCAAGGATCTCTGAAGATTAAGGTAGGAATGTGAAACC
ATTTCTAAGGTGGAAATCTTGCTGTTAAGTCACAGGTCCTGGGTGTAACGGGGGTGGTGAAAGTCTGTATTTTGGTTGTTTCCATACAGT
CAGTTCCACCAATTGGGTGAAAGCAGGTGAAATCTTTTTGCTGCAGGGTGGACTGAATTTTTCACTTTCTGGGTAGTTGTTTTGATCATG
TGTAGGCGAATTCCAGGTAACTTACAGCAAATAGATTTGGGATGGAAAATACCAGACCTCTGGTTGTGTCAGGGTTTATCCTAATAGCTT
TCCTGAGACAGAGCTCAGACTTTCATTTTTGATCTTCCACCCCAGGGCCCCCTCTCTGTCTATGGGATCCTTTCTCCCCTCTCTCTACCA
TTTTCCCGTACCTTCCCCCATAAGTCACTCCCAAGAGCCTGGGCAGGTCTTTGAGGAATTGCGGCTCATTTTGGCAGCCCCGTCCTGCAA
TTACCTTTGGGTTTGAAAGAATAGCTGTGGGTGGGCAATTGAGGACACCTCTTTAGTCAGGGACCTTTCTAGCAATCCACTCCCTCCCAT
CCTGTTAGCCATGCAGTGGAACTCTCCTTCCCTCTCTGCCCCAACCCCGGTGATGGCTCACTCTCAGCATCTTATGGGACCATCTGAGTT
AACAACCCTGTTCCAAGAAGACTTTGTGCAGAACTTTTGTTAGGGTGGTCATACCTTCTCACCACCATTTGGAAGACACAGCCTAATGCT
GATGTACTTAATGTGCCCCTTCCGGCATAGAAATAATGTCTGGGTAACAGCCATCAAAATCACTAAGAATGACATTGGATAGCTATGAGA
AAGTAGTAGAGAATTGATTTAAAATATCATTCTTGTTTGGTATAGATTAAACTAGGAAATGTTCTCTCTGAAGCATGAAAATGTTTTTCC
CATGTGAAGTTTAGTACAAGGATGGAAAAATAATAATCACAGTAGACTTTGAACAATGCAACTGTATCTCTGAATATCCACATTTAAAAA
TAGCCTTCACTGAATGCTGAATTGCATTTCCCATTAATTTTTGGTTTTAAAAATTTTGTAAACTTTTTTTTTATTTGGAATTTAGTCACA
TCCATTAAATTTTCCAATCTAGTTTCTGTGGAAATTTTTTAACAGAGAGAAACAAATAGAAACATCTTCAAATCTTCCTAAGTGAATATT
TAAAATGCAGAATTGCTTATCTTCTGTTTTTCTGTATTCAGACACTTATATCTGTTGTATATATTAGTTTAGACACTCTCACTAATATAC
ACAGTATTTAAGACTCTAAATGAGATTTCTTAAGTATTTTATTTTATTCTCTGTAAATGGTTTTGTATAATCTTTAAACATCTACACTTT
GCCTTTGTAGATATTTAAGGGAAACCATTTGGGGTTGTCTTGCATGTATATTTTTGTTGTAGATAAGTGTTGCTTAGTTATTTCTGCAAA
TTTTGGTTGAAATGCTTACAGACTTTAATACAGTATATATTTTCAAAATATAAACTTTTATATTTCTGTGATAAGTTAGGATATGCGTTT
TAGGCAATATTTTTCATTAATATCACTTGTTCTTTTGAAAAATAGCATACTGGTTTGGTGCCAATTTTTTCATTAGAATATAATGCTCTT
ATATTGTTGGAGAGCAGGTTAATCTTTTTTCGAAGTAATTGCGTTTGAAGTATAATTTCAAAATGTATTGAATTTGTGAATAAGCCTTAC
CATTAGGATCAGTAAATTTTTCAACTTTGCAACTACATAAGTAGTTTAAGATCTCCCCGTAAATTCTCACTGTGTGGCAGTTGATGGAGT
TTGTGAACAGAGCCTTAAGCTTGTTGCAAAAAAATTTAAAAAGGGTAATACGGGTTGTTTCCTCCATGCAACGTAAGCCATGCTGATGGA
CTGAATGCAGTCTGTAATTCATGGCTAATCCGAAGAGTTTGATTGAGTTGATGGCGGCAGGGACCAGATAGACACCTTGGTGATTGTCTT
TGGCCATAAGAATAGACCAAGGATAGGTTTTCCAGAGACACCTTCATACTGTAAACATGGTTTAGACACGGTCATAGGGAAGGCTGCTGG
TCCATCATTTGTTCTGAACAAATGGCATTTCCTGCTCCTGACCCTGGCAGTTGGCCCCAGATTCCTTGTCGATGACTTGGAAACGTCCAT
TCTGGGTAAGGTCAGCACTCCCTGAGAGATGTTAACAAAGTTTACCTATGAGTCTTACTGTGTAGACAATCTGAAGTCAATTTTAGTTAC
ACAATCAGCATTCCCATGTGTCCTCAGTGTCTTATCAATGAACTATGTGTATCAAGCCATACTAAACTGGAGTTTAGCAGGACAAAGGCA
AACTAAATGTAGAACATAACATATCAGCTGAATATGTCTATCCAGGACTGTTTTTCTAGAACATAAATCATGGAGCTCCTTGACAGTGTA
TCCACTGTTTTTGGGGTTTAATAAAACCAACTAGAATTTAGACTTAAAAAGAAATTATTATTCCTTTTGGTTGTCCACATAAAGTAGTCC
AGGGCTATCATATGGCTAAAATCAAGTTATTTGGTTCATCTCTGGTATGTATTTATAAAGTCAACTTATCAGCCATTAAGATGGAGATTT
GCTTTAAATTTTTGCAGTGTGTGTGGCAGTCAGAAAAACCCATATCTAGTTTTCAACTTCACCTCTGGTGTTTTTATGGCTTAACCTTAT
ATCATTGATCCAACATCTAGCCTGATGCTGGAGCTCTTATTTCTAGCCTGATGCTGGAGCTCTTATATCTAGCCTGATGCTGGAGCTCTT
GAAGCTGACTCTTGGAAGTTTGGAGGGTGTAGAGTTTCCCATCTAGTATTTAATTTGTCCCTGTGCCATTAGTCCCAGCTTGAAGTCATT
TGCCAGTGTCGATGTTGACAGGATTGTGACAATATTGCCTTTCATAAAACCGAGAACCAAAGAATTCCATTATTCTAACAAAGCCTGAGT
TTCATAGATTGTGGGCACATCTAGACAGATATGTGCATGCTTGATGGTGCAGAGAAACTGCTGACTTCCACCAACCTCATGCTCCCCCTG
GCTGGCCATACAGAGGGATTCGTTGTCATATTGAAAAGGCTCTGAAAGATGAGTTTCTAATTGAAGCTCACTATCTCAGGTTGGTGTTTC
TACTGTGTAGTCCCAAGCCTGTATCCATATCATAAAAGTGGAGGCCTGGTACTCCTCCAGGTTATCTGGCCAGTGTAGACTCCTCCATCT
GAATATGAACCTCCAGGGTAAGAATTTTTCAGACATGTCTATACTGAACAGTAGGATCCTGCACTTTCCAAATGTCTGCCTCCTTTTGTT
CTTCATTGACCCATTCTAATTCCTGTTAGGTGTGAGAAGAATTGTCTTCAGTTCTCTCTCCATTCTCATTCATGATGGAATCATTGATCC
ATTGACCAGTTGAGAAATGATTGATGCTGAAGAAGTGGTATTCTATTGGTAAGGCTTATTACCAAACTTCCGATAATGAAGCAGGCTACC
AAAAACTTATCCAGCCCACCCTAGGAGTGTTTGGATTTGATCATGGATGTAGCATACACCAAAATCCACCGAGACCTTTGCAAAATTAGG
CTACTTGTTTTATTTTGCCAGATTATCATGGGAGAGTCTTTAACTAGTTCTGAATATTTGTAAGTCTGAGTACTTCATAGAATTATAAAG
AAGGTACAGCTGACCCCTTCTCACCATGTTGTAAATATTTACTGAGACTGGGTGCAGTACTGAGGGATAATAATCTTCTGATTTATCAAA
TCCTGACTGTCTAGAGCAAATTGTACACTCTCTTTGTGAATGGTCCTGTAACGTGTATGAACACATTTCTGGGTGCCTTAGAAGTTGTAT
TTTTCATGTGTGCTAATATGCAGTATTTATACATTGTGAGAAGCTGCTTTGAATAAAAAGGTTGAAACTTC

>17521_17521_4_CMIP-CDYL2_CMIP_chr16_81479146_ENST00000537098_CDYL2_chr16_80719026_ENST00000570137_length(amino acids)=598AA_BP=95
MDVTSSSGGGGDPRQIEETKPLLGGDVSAPEGTKMGAVPCRRALLLCNGMRYKLLQEGDIQVCVIRHPRTFLSKILTSKFLRRWEPHHLT
LADNSLASATVERIVDKRKNKKGKWEYLIRWKGYGSTEDTWEPEHHLLHCEEFIDEFNGLHMSKDKRIKSGKQSSTSKLLRDSRGPSVEK
LSHRPSDPGKSKGTSHKRKRINPPLAKPKKGYSGKPSSGGDRATKTVSYRTTPSGLQIMPLKKSQNGMENGDAGSEKDERHFGNGSHQPG
LDLNDHVGEQDMGECDVNHATLAENGLGSALTNGGLNLHSPVKRKLEAEKDYVFDKRLRYSVRQNESNCRFRDIVVRKEEGFTHILLSSQ
TSDNNALTPEIMKEVRRALCNAATDDSKLLLLSAVGSVFCSGLDYSYLIGRLSSDRRKESTRIAEAIRDFVKAFIQFKKPIVVAINGPAL
GLGASILPLCDIVWASEKAWFQTPYATIRLTPAGCSSYTFPQILGVALANEMLFCGRKLTAQEACSRGLVSQVFWPTTFSQEVMLRVKEM
ASCSAVVLEESKCLVRSFLKSVLEDVNEKECLMLKQLWSSSKGLDSLFSYLQDKIYEV

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CMIP-CDYL2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CMIP-CDYL2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CMIP-CDYL2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCMIPC0011860Diabetes Mellitus, Non-Insulin-Dependent1CTD_human