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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ACTN4-RPS16 (FusionGDB2 ID:HG81TG6217)

Fusion Gene Summary for ACTN4-RPS16

check button Fusion gene summary
Fusion gene informationFusion gene name: ACTN4-RPS16
Fusion gene ID: hg81tg6217
HgeneTgene
Gene symbol

ACTN4

RPS16

Gene ID

81

6217

Gene nameactinin alpha 4ribosomal protein S16
SynonymsACTININ-4|FSGS|FSGS1S16
Cytomap('ACTN4')('RPS16')

19q13.2

19q13.2

Type of geneprotein-codingprotein-coding
Descriptionalpha-actinin-4focal segmental glomerulosclerosis 1non-muscle alpha-actinin 440S ribosomal protein S16small ribosomal subunit protein uS9
Modification date2020032720200313
UniProtAcc

O43707

.
Ensembl transtripts involved in fusion geneENST00000252699, ENST00000390009, 
ENST00000424234, ENST00000497637, 
Fusion gene scores* DoF score42 X 60 X 18=4536015 X 11 X 6=990
# samples 7716
** MAII scorelog2(77/45360*10)=-5.88041838424733
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(16/990*10)=-2.62935662007961
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ACTN4 [Title/Abstract] AND RPS16 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointACTN4(39138547)-RPS16(39926348), # samples:3
Anticipated loss of major functional domain due to fusion event.ACTN4-RPS16 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ACTN4-RPS16 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ACTN4-RPS16 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ACTN4-RPS16 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneACTN4

GO:0033209

tumor necrosis factor-mediated signaling pathway

25411248

HgeneACTN4

GO:0035357

peroxisome proliferator activated receptor signaling pathway

22351778

HgeneACTN4

GO:0048384

retinoic acid receptor signaling pathway

22351778

HgeneACTN4

GO:0051272

positive regulation of cellular component movement

9508771


check buttonFusion gene breakpoints across ACTN4 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across RPS16 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-44-2662-01AACTN4chr19

39138546

+RPS16chr19

39924400

-
ChimerDB4LUADTCGA-44-2662-01AACTN4chr19

39138547

+RPS16chr19

39924401

-
ChimerDB4LUADTCGA-44-2662-01AACTN4chr19

39138547

+RPS16chr19

39926348

-


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Fusion Gene ORF analysis for ACTN4-RPS16

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000252699ENST00000251453ACTN4chr19

39138546

+RPS16chr19

39924400

-
In-frameENST00000252699ENST00000251453ACTN4chr19

39138547

+RPS16chr19

39924401

-
In-frameENST00000252699ENST00000251453ACTN4chr19

39138547

+RPS16chr19

39926348

-
In-frameENST00000252699ENST00000339471ACTN4chr19

39138546

+RPS16chr19

39924400

-
In-frameENST00000252699ENST00000339471ACTN4chr19

39138547

+RPS16chr19

39924401

-
In-frameENST00000252699ENST00000339471ACTN4chr19

39138547

+RPS16chr19

39926348

-
In-frameENST00000252699ENST00000599539ACTN4chr19

39138546

+RPS16chr19

39924400

-
In-frameENST00000252699ENST00000599539ACTN4chr19

39138547

+RPS16chr19

39924401

-
In-frameENST00000252699ENST00000599539ACTN4chr19

39138547

+RPS16chr19

39926348

-
In-frameENST00000252699ENST00000601655ACTN4chr19

39138546

+RPS16chr19

39924400

-
In-frameENST00000252699ENST00000601655ACTN4chr19

39138547

+RPS16chr19

39924401

-
In-frameENST00000252699ENST00000601655ACTN4chr19

39138547

+RPS16chr19

39926348

-
In-frameENST00000390009ENST00000251453ACTN4chr19

39138546

+RPS16chr19

39924400

-
In-frameENST00000390009ENST00000251453ACTN4chr19

39138547

+RPS16chr19

39924401

-
In-frameENST00000390009ENST00000251453ACTN4chr19

39138547

+RPS16chr19

39926348

-
In-frameENST00000390009ENST00000339471ACTN4chr19

39138546

+RPS16chr19

39924400

-
In-frameENST00000390009ENST00000339471ACTN4chr19

39138547

+RPS16chr19

39924401

-
In-frameENST00000390009ENST00000339471ACTN4chr19

39138547

+RPS16chr19

39926348

-
In-frameENST00000390009ENST00000599539ACTN4chr19

39138546

+RPS16chr19

39924400

-
In-frameENST00000390009ENST00000599539ACTN4chr19

39138547

+RPS16chr19

39924401

-
In-frameENST00000390009ENST00000599539ACTN4chr19

39138547

+RPS16chr19

39926348

-
In-frameENST00000390009ENST00000601655ACTN4chr19

39138546

+RPS16chr19

39924400

-
In-frameENST00000390009ENST00000601655ACTN4chr19

39138547

+RPS16chr19

39924401

-
In-frameENST00000390009ENST00000601655ACTN4chr19

39138547

+RPS16chr19

39926348

-
In-frameENST00000424234ENST00000251453ACTN4chr19

39138546

+RPS16chr19

39924400

-
In-frameENST00000424234ENST00000251453ACTN4chr19

39138547

+RPS16chr19

39924401

-
In-frameENST00000424234ENST00000251453ACTN4chr19

39138547

+RPS16chr19

39926348

-
In-frameENST00000424234ENST00000339471ACTN4chr19

39138546

+RPS16chr19

39924400

-
In-frameENST00000424234ENST00000339471ACTN4chr19

39138547

+RPS16chr19

39924401

-
In-frameENST00000424234ENST00000339471ACTN4chr19

39138547

+RPS16chr19

39926348

-
In-frameENST00000424234ENST00000599539ACTN4chr19

39138546

+RPS16chr19

39924400

-
In-frameENST00000424234ENST00000599539ACTN4chr19

39138547

+RPS16chr19

39924401

-
In-frameENST00000424234ENST00000599539ACTN4chr19

39138547

+RPS16chr19

39926348

-
In-frameENST00000424234ENST00000601655ACTN4chr19

39138546

+RPS16chr19

39924400

-
In-frameENST00000424234ENST00000601655ACTN4chr19

39138547

+RPS16chr19

39924401

-
In-frameENST00000424234ENST00000601655ACTN4chr19

39138547

+RPS16chr19

39926348

-
intron-3CDSENST00000497637ENST00000251453ACTN4chr19

39138546

+RPS16chr19

39924400

-
intron-3CDSENST00000497637ENST00000251453ACTN4chr19

39138547

+RPS16chr19

39924401

-
intron-3CDSENST00000497637ENST00000251453ACTN4chr19

39138547

+RPS16chr19

39926348

-
intron-3CDSENST00000497637ENST00000339471ACTN4chr19

39138546

+RPS16chr19

39924400

-
intron-3CDSENST00000497637ENST00000339471ACTN4chr19

39138547

+RPS16chr19

39924401

-
intron-3CDSENST00000497637ENST00000339471ACTN4chr19

39138547

+RPS16chr19

39926348

-
intron-3CDSENST00000497637ENST00000599539ACTN4chr19

39138546

+RPS16chr19

39924400

-
intron-3CDSENST00000497637ENST00000599539ACTN4chr19

39138547

+RPS16chr19

39924401

-
intron-3CDSENST00000497637ENST00000599539ACTN4chr19

39138547

+RPS16chr19

39926348

-
intron-3CDSENST00000497637ENST00000601655ACTN4chr19

39138546

+RPS16chr19

39924400

-
intron-3CDSENST00000497637ENST00000601655ACTN4chr19

39138547

+RPS16chr19

39924401

-
intron-3CDSENST00000497637ENST00000601655ACTN4chr19

39138547

+RPS16chr19

39926348

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000252699ACTN4chr1939138547+ENST00000599539RPS16chr1939926348-72523876492138
ENST00000252699ACTN4chr1939138547+ENST00000339471RPS16chr1939926348-79223876648190
ENST00000252699ACTN4chr1939138547+ENST00000251453RPS16chr1939926348-69723876630184
ENST00000252699ACTN4chr1939138547+ENST00000601655RPS16chr1939926348-63623876579167
ENST00000424234ACTN4chr1939138547+ENST00000599539RPS16chr1939926348-70822159475138
ENST00000424234ACTN4chr1939138547+ENST00000339471RPS16chr1939926348-77522159631190
ENST00000424234ACTN4chr1939138547+ENST00000251453RPS16chr1939926348-68022159613184
ENST00000424234ACTN4chr1939138547+ENST00000601655RPS16chr1939926348-61922159562167
ENST00000390009ACTN4chr1939138547+ENST00000599539RPS16chr1939926348-6571708424138
ENST00000390009ACTN4chr1939138547+ENST00000339471RPS16chr1939926348-7241708580190
ENST00000390009ACTN4chr1939138547+ENST00000251453RPS16chr1939926348-6291708562184
ENST00000390009ACTN4chr1939138547+ENST00000601655RPS16chr1939926348-5681708511167
ENST00000252699ACTN4chr1939138547+ENST00000599539RPS16chr1939924401-6232385041168
ENST00000252699ACTN4chr1939138547+ENST00000339471RPS16chr1939924401-69023876546156
ENST00000252699ACTN4chr1939138547+ENST00000251453RPS16chr1939924401-5952385341178
ENST00000252699ACTN4chr1939138547+ENST00000601655RPS16chr1939924401-58523876528150
ENST00000424234ACTN4chr1939138547+ENST00000599539RPS16chr1939924401-6062214872162
ENST00000424234ACTN4chr1939138547+ENST00000339471RPS16chr1939924401-67322159529156
ENST00000424234ACTN4chr1939138547+ENST00000251453RPS16chr1939924401-5782215172172
ENST00000424234ACTN4chr1939138547+ENST00000601655RPS16chr1939924401-56822159511150
ENST00000390009ACTN4chr1939138547+ENST00000599539RPS16chr1939924401-5551704362145
ENST00000390009ACTN4chr1939138547+ENST00000339471RPS16chr1939924401-6221708478156
ENST00000390009ACTN4chr1939138547+ENST00000251453RPS16chr1939924401-5271704662155
ENST00000390009ACTN4chr1939138547+ENST00000601655RPS16chr1939924401-5171708460150
ENST00000252699ACTN4chr1939138546+ENST00000599539RPS16chr1939924400-6232385041168
ENST00000252699ACTN4chr1939138546+ENST00000339471RPS16chr1939924400-69023876546156
ENST00000252699ACTN4chr1939138546+ENST00000251453RPS16chr1939924400-5952385341178
ENST00000252699ACTN4chr1939138546+ENST00000601655RPS16chr1939924400-58523876528150
ENST00000424234ACTN4chr1939138546+ENST00000599539RPS16chr1939924400-6062214872162
ENST00000424234ACTN4chr1939138546+ENST00000339471RPS16chr1939924400-67322159529156
ENST00000424234ACTN4chr1939138546+ENST00000251453RPS16chr1939924400-5782215172172
ENST00000424234ACTN4chr1939138546+ENST00000601655RPS16chr1939924400-56822159511150
ENST00000390009ACTN4chr1939138546+ENST00000599539RPS16chr1939924400-5551704362145
ENST00000390009ACTN4chr1939138546+ENST00000339471RPS16chr1939924400-6221708478156
ENST00000390009ACTN4chr1939138546+ENST00000251453RPS16chr1939924400-5271704662155
ENST00000390009ACTN4chr1939138546+ENST00000601655RPS16chr1939924400-5171708460150

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000252699ENST00000599539ACTN4chr1939138547+RPS16chr1939926348-0.0169390590.9830609
ENST00000252699ENST00000339471ACTN4chr1939138547+RPS16chr1939926348-0.324752360.6752476
ENST00000252699ENST00000251453ACTN4chr1939138547+RPS16chr1939926348-0.004353480.99564654
ENST00000252699ENST00000601655ACTN4chr1939138547+RPS16chr1939926348-0.0067080340.993292
ENST00000424234ENST00000599539ACTN4chr1939138547+RPS16chr1939926348-0.0185478890.98145217
ENST00000424234ENST00000339471ACTN4chr1939138547+RPS16chr1939926348-0.36884480.6311552
ENST00000424234ENST00000251453ACTN4chr1939138547+RPS16chr1939926348-0.0047141060.9952859
ENST00000424234ENST00000601655ACTN4chr1939138547+RPS16chr1939926348-0.0069919330.993008
ENST00000390009ENST00000599539ACTN4chr1939138547+RPS16chr1939926348-0.0124850730.987515
ENST00000390009ENST00000339471ACTN4chr1939138547+RPS16chr1939926348-0.270697330.7293027
ENST00000390009ENST00000251453ACTN4chr1939138547+RPS16chr1939926348-0.003418320.99658173
ENST00000390009ENST00000601655ACTN4chr1939138547+RPS16chr1939926348-0.0044073520.99559265
ENST00000252699ENST00000599539ACTN4chr1939138547+RPS16chr1939924401-0.046151030.953849
ENST00000252699ENST00000339471ACTN4chr1939138547+RPS16chr1939924401-0.595043360.40495667
ENST00000252699ENST00000251453ACTN4chr1939138547+RPS16chr1939924401-0.0071292550.99287075
ENST00000252699ENST00000601655ACTN4chr1939138547+RPS16chr1939924401-0.0067364970.99326354
ENST00000424234ENST00000599539ACTN4chr1939138547+RPS16chr1939924401-0.0513283350.94867164
ENST00000424234ENST00000339471ACTN4chr1939138547+RPS16chr1939924401-0.688479660.3115204
ENST00000424234ENST00000251453ACTN4chr1939138547+RPS16chr1939924401-0.0076705550.9923294
ENST00000424234ENST00000601655ACTN4chr1939138547+RPS16chr1939924401-0.0080142560.9919857
ENST00000390009ENST00000599539ACTN4chr1939138547+RPS16chr1939924401-0.0293102970.97068965
ENST00000390009ENST00000339471ACTN4chr1939138547+RPS16chr1939924401-0.5421850.457815
ENST00000390009ENST00000251453ACTN4chr1939138547+RPS16chr1939924401-0.0063513920.9936486
ENST00000390009ENST00000601655ACTN4chr1939138547+RPS16chr1939924401-0.0067377540.99326223
ENST00000252699ENST00000599539ACTN4chr1939138546+RPS16chr1939924400-0.046151030.953849
ENST00000252699ENST00000339471ACTN4chr1939138546+RPS16chr1939924400-0.595043360.40495667
ENST00000252699ENST00000251453ACTN4chr1939138546+RPS16chr1939924400-0.0071292550.99287075
ENST00000252699ENST00000601655ACTN4chr1939138546+RPS16chr1939924400-0.0067364970.99326354
ENST00000424234ENST00000599539ACTN4chr1939138546+RPS16chr1939924400-0.0513283350.94867164
ENST00000424234ENST00000339471ACTN4chr1939138546+RPS16chr1939924400-0.688479660.3115204
ENST00000424234ENST00000251453ACTN4chr1939138546+RPS16chr1939924400-0.0076705550.9923294
ENST00000424234ENST00000601655ACTN4chr1939138546+RPS16chr1939924400-0.0080142560.9919857
ENST00000390009ENST00000599539ACTN4chr1939138546+RPS16chr1939924400-0.0293102970.97068965
ENST00000390009ENST00000339471ACTN4chr1939138546+RPS16chr1939924400-0.5421850.457815
ENST00000390009ENST00000251453ACTN4chr1939138546+RPS16chr1939924400-0.0063513920.9936486
ENST00000390009ENST00000601655ACTN4chr1939138546+RPS16chr1939924400-0.0067377540.99326223

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Fusion Genomic Features for ACTN4-RPS16


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for ACTN4-RPS16


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:39138547/chr19:39926348)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ACTN4

O43707

.
FUNCTION: F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (Probable). Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation (PubMed:15772161). Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions (By similarity). May also function as a transcriptional coactivator, stimulating transcription mediated by the nuclear hormone receptors PPARG and RARA (PubMed:22351778). {ECO:0000250|UniProtKB:P57780, ECO:0000269|PubMed:15772161, ECO:0000269|PubMed:22351778, ECO:0000305|PubMed:9508771}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneACTN4chr19:39138546chr19:39924400ENST00000252699+12119_2654912.0Compositional biasPoly-Gly
HgeneACTN4chr19:39138546chr19:39924400ENST00000390009+11419_2654693.0Compositional biasPoly-Gly
HgeneACTN4chr19:39138547chr19:39924401ENST00000252699+12119_2654912.0Compositional biasPoly-Gly
HgeneACTN4chr19:39138547chr19:39924401ENST00000390009+11419_2654693.0Compositional biasPoly-Gly
HgeneACTN4chr19:39138547chr19:39926348ENST00000252699+12119_2654912.0Compositional biasPoly-Gly
HgeneACTN4chr19:39138547chr19:39926348ENST00000390009+11419_2654693.0Compositional biasPoly-Gly

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneACTN4chr19:39138546chr19:39924400ENST00000252699+121778_78954912.0Calcium binding1
HgeneACTN4chr19:39138546chr19:39924400ENST00000252699+121819_83054912.0Calcium binding2
HgeneACTN4chr19:39138546chr19:39924400ENST00000390009+114778_78954693.0Calcium binding1
HgeneACTN4chr19:39138546chr19:39924400ENST00000390009+114819_83054693.0Calcium binding2
HgeneACTN4chr19:39138547chr19:39924401ENST00000252699+121778_78954912.0Calcium binding1
HgeneACTN4chr19:39138547chr19:39924401ENST00000252699+121819_83054912.0Calcium binding2
HgeneACTN4chr19:39138547chr19:39924401ENST00000390009+114778_78954693.0Calcium binding1
HgeneACTN4chr19:39138547chr19:39924401ENST00000390009+114819_83054693.0Calcium binding2
HgeneACTN4chr19:39138547chr19:39926348ENST00000252699+121778_78954912.0Calcium binding1
HgeneACTN4chr19:39138547chr19:39926348ENST00000252699+121819_83054912.0Calcium binding2
HgeneACTN4chr19:39138547chr19:39926348ENST00000390009+114778_78954693.0Calcium binding1
HgeneACTN4chr19:39138547chr19:39926348ENST00000390009+114819_83054693.0Calcium binding2
HgeneACTN4chr19:39138546chr19:39924400ENST00000252699+121163_26954912.0DomainCalponin-homology (CH) 2
HgeneACTN4chr19:39138546chr19:39924400ENST00000252699+12150_15454912.0DomainCalponin-homology (CH) 1
HgeneACTN4chr19:39138546chr19:39924400ENST00000252699+121765_80054912.0DomainEF-hand 1
HgeneACTN4chr19:39138546chr19:39924400ENST00000252699+121806_84154912.0DomainEF-hand 2
HgeneACTN4chr19:39138546chr19:39924400ENST00000390009+114163_26954693.0DomainCalponin-homology (CH) 2
HgeneACTN4chr19:39138546chr19:39924400ENST00000390009+11450_15454693.0DomainCalponin-homology (CH) 1
HgeneACTN4chr19:39138546chr19:39924400ENST00000390009+114765_80054693.0DomainEF-hand 1
HgeneACTN4chr19:39138546chr19:39924400ENST00000390009+114806_84154693.0DomainEF-hand 2
HgeneACTN4chr19:39138547chr19:39924401ENST00000252699+121163_26954912.0DomainCalponin-homology (CH) 2
HgeneACTN4chr19:39138547chr19:39924401ENST00000252699+12150_15454912.0DomainCalponin-homology (CH) 1
HgeneACTN4chr19:39138547chr19:39924401ENST00000252699+121765_80054912.0DomainEF-hand 1
HgeneACTN4chr19:39138547chr19:39924401ENST00000252699+121806_84154912.0DomainEF-hand 2
HgeneACTN4chr19:39138547chr19:39924401ENST00000390009+114163_26954693.0DomainCalponin-homology (CH) 2
HgeneACTN4chr19:39138547chr19:39924401ENST00000390009+11450_15454693.0DomainCalponin-homology (CH) 1
HgeneACTN4chr19:39138547chr19:39924401ENST00000390009+114765_80054693.0DomainEF-hand 1
HgeneACTN4chr19:39138547chr19:39924401ENST00000390009+114806_84154693.0DomainEF-hand 2
HgeneACTN4chr19:39138547chr19:39926348ENST00000252699+121163_26954912.0DomainCalponin-homology (CH) 2
HgeneACTN4chr19:39138547chr19:39926348ENST00000252699+12150_15454912.0DomainCalponin-homology (CH) 1
HgeneACTN4chr19:39138547chr19:39926348ENST00000252699+121765_80054912.0DomainEF-hand 1
HgeneACTN4chr19:39138547chr19:39926348ENST00000252699+121806_84154912.0DomainEF-hand 2
HgeneACTN4chr19:39138547chr19:39926348ENST00000390009+114163_26954693.0DomainCalponin-homology (CH) 2
HgeneACTN4chr19:39138547chr19:39926348ENST00000390009+11450_15454693.0DomainCalponin-homology (CH) 1
HgeneACTN4chr19:39138547chr19:39926348ENST00000390009+114765_80054693.0DomainEF-hand 1
HgeneACTN4chr19:39138547chr19:39926348ENST00000390009+114806_84154693.0DomainEF-hand 2
HgeneACTN4chr19:39138546chr19:39924400ENST00000252699+12184_8854912.0MotifLXXLL motif
HgeneACTN4chr19:39138546chr19:39924400ENST00000390009+11484_8854693.0MotifLXXLL motif
HgeneACTN4chr19:39138547chr19:39924401ENST00000252699+12184_8854912.0MotifLXXLL motif
HgeneACTN4chr19:39138547chr19:39924401ENST00000390009+11484_8854693.0MotifLXXLL motif
HgeneACTN4chr19:39138547chr19:39926348ENST00000252699+12184_8854912.0MotifLXXLL motif
HgeneACTN4chr19:39138547chr19:39926348ENST00000390009+11484_8854693.0MotifLXXLL motif
HgeneACTN4chr19:39138546chr19:39924400ENST00000252699+121177_19254912.0RegionPolyphosphoinositide (PIP2)-binding
HgeneACTN4chr19:39138546chr19:39924400ENST00000252699+1211_26954912.0RegionNote=Actin-binding
HgeneACTN4chr19:39138546chr19:39924400ENST00000390009+114177_19254693.0RegionPolyphosphoinositide (PIP2)-binding
HgeneACTN4chr19:39138546chr19:39924400ENST00000390009+1141_26954693.0RegionNote=Actin-binding
HgeneACTN4chr19:39138547chr19:39924401ENST00000252699+121177_19254912.0RegionPolyphosphoinositide (PIP2)-binding
HgeneACTN4chr19:39138547chr19:39924401ENST00000252699+1211_26954912.0RegionNote=Actin-binding
HgeneACTN4chr19:39138547chr19:39924401ENST00000390009+114177_19254693.0RegionPolyphosphoinositide (PIP2)-binding
HgeneACTN4chr19:39138547chr19:39924401ENST00000390009+1141_26954693.0RegionNote=Actin-binding
HgeneACTN4chr19:39138547chr19:39926348ENST00000252699+121177_19254912.0RegionPolyphosphoinositide (PIP2)-binding
HgeneACTN4chr19:39138547chr19:39926348ENST00000252699+1211_26954912.0RegionNote=Actin-binding
HgeneACTN4chr19:39138547chr19:39926348ENST00000390009+114177_19254693.0RegionPolyphosphoinositide (PIP2)-binding
HgeneACTN4chr19:39138547chr19:39926348ENST00000390009+1141_26954693.0RegionNote=Actin-binding
HgeneACTN4chr19:39138546chr19:39924400ENST00000252699+121293_40354912.0RepeatSpectrin 1
HgeneACTN4chr19:39138546chr19:39924400ENST00000252699+121413_51854912.0RepeatSpectrin 2
HgeneACTN4chr19:39138546chr19:39924400ENST00000252699+121528_63954912.0RepeatSpectrin 3
HgeneACTN4chr19:39138546chr19:39924400ENST00000252699+121649_75254912.0RepeatSpectrin 4
HgeneACTN4chr19:39138546chr19:39924400ENST00000390009+114293_40354693.0RepeatSpectrin 1
HgeneACTN4chr19:39138546chr19:39924400ENST00000390009+114413_51854693.0RepeatSpectrin 2
HgeneACTN4chr19:39138546chr19:39924400ENST00000390009+114528_63954693.0RepeatSpectrin 3
HgeneACTN4chr19:39138546chr19:39924400ENST00000390009+114649_75254693.0RepeatSpectrin 4
HgeneACTN4chr19:39138547chr19:39924401ENST00000252699+121293_40354912.0RepeatSpectrin 1
HgeneACTN4chr19:39138547chr19:39924401ENST00000252699+121413_51854912.0RepeatSpectrin 2
HgeneACTN4chr19:39138547chr19:39924401ENST00000252699+121528_63954912.0RepeatSpectrin 3
HgeneACTN4chr19:39138547chr19:39924401ENST00000252699+121649_75254912.0RepeatSpectrin 4
HgeneACTN4chr19:39138547chr19:39924401ENST00000390009+114293_40354693.0RepeatSpectrin 1
HgeneACTN4chr19:39138547chr19:39924401ENST00000390009+114413_51854693.0RepeatSpectrin 2
HgeneACTN4chr19:39138547chr19:39924401ENST00000390009+114528_63954693.0RepeatSpectrin 3
HgeneACTN4chr19:39138547chr19:39924401ENST00000390009+114649_75254693.0RepeatSpectrin 4
HgeneACTN4chr19:39138547chr19:39926348ENST00000252699+121293_40354912.0RepeatSpectrin 1
HgeneACTN4chr19:39138547chr19:39926348ENST00000252699+121413_51854912.0RepeatSpectrin 2
HgeneACTN4chr19:39138547chr19:39926348ENST00000252699+121528_63954912.0RepeatSpectrin 3
HgeneACTN4chr19:39138547chr19:39926348ENST00000252699+121649_75254912.0RepeatSpectrin 4
HgeneACTN4chr19:39138547chr19:39926348ENST00000390009+114293_40354693.0RepeatSpectrin 1
HgeneACTN4chr19:39138547chr19:39926348ENST00000390009+114413_51854693.0RepeatSpectrin 2
HgeneACTN4chr19:39138547chr19:39926348ENST00000390009+114528_63954693.0RepeatSpectrin 3
HgeneACTN4chr19:39138547chr19:39926348ENST00000390009+114649_75254693.0RepeatSpectrin 4


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Fusion Gene Sequence for ACTN4-RPS16


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>1798_1798_1_ACTN4-RPS16_ACTN4_chr19_39138546_ENST00000252699_RPS16_chr19_39924400_ENST00000251453_length(transcript)=595nt_BP=238nt
GCGGCGGCGGCTCGGGCAGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCA
CGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGA
GGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGCTGCTGGAGCCAGTTCTGCTTCTCGGCAAGGA
GCGATTTGCTGGTGTAGACATCCGTGTCCGTGTAAAGGGTGGTGGTCACGTGGCCCAGATTTATGCTATCCGTCAGTCCATCTCCAAAGC
CCTGGTGGCCTATTACCAGAAATATGTGGATGAGGCTTCCAAGAAGGAGATCAAAGACATCCTCATCCAGTATGACCGGACCCTGCTGGT
AGCTGACCCTCGTCGCTGCGAGTCCAAAAAGTTTGGAGGCCCTGGTGCCCGCGCTCGCTACCAGAAATCCTACCGATAAGCCCATCGTGA
CTCAAAACTCACTTGTATAATAAACAGTTTTTGAGGGATTTTAAAGTTTCAAGAA

>1798_1798_1_ACTN4-RPS16_ACTN4_chr19_39138546_ENST00000252699_RPS16_chr19_39924400_ENST00000251453_length(amino acids)=178AA_BP=0
MGLSVGFLVASAGTRASKLFGLAATRVSYQQGPVILDEDVFDLLLGSLIHIFLVIGHQGFGDGLTDSINLGHVTTTLYTDTDVYTSKSLL
AEKQNWLQQLALLLLPGRVQQQVPVPVVLLGHVVAHAAPAASAIARAAGAVLVRLVRRVVVHHSAASRSPTSLSAPASAPAPLPEPPP

--------------------------------------------------------------
>1798_1798_2_ACTN4-RPS16_ACTN4_chr19_39138546_ENST00000252699_RPS16_chr19_39924400_ENST00000339471_length(transcript)=690nt_BP=238nt
GCGGCGGCGGCTCGGGCAGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCA
CGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGA
GGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGCTGCTGGAGCCAGTTCTGCTTCTCGGCAAGGA
GCGATTTGCTGGTGTAGACATCCGTGTCCGTGTAAAGGGTGGTGGTCACGTGGCCCAGATTTATGGTGAGTCCCAGGAACTGGGCGCATG
GAGGAGGTGGCTCTGGGAGGGAGGCCTTCACAGCGCTCCTGTACCCTTTAATTGTGTGTCTTTCTCACAGCTATCCGTCAGTCCATCTCC
AAAGCCCTGGTGGCCTATTACCAGAAATATGTGGATGAGGCTTCCAAGAAGGAGATCAAAGACATCCTCATCCAGTATGACCGGACCCTG
CTGGTAGCTGACCCTCGTCGCTGCGAGTCCAAAAAGTTTGGAGGCCCTGGTGCCCGCGCTCGCTACCAGAAATCCTACCGATAAGCCCAT
CGTGACTCAAAACTCACTTGTATAATAAACAGTTTTTGAGGGATTTTAAAGTTTCAAGAA

>1798_1798_2_ACTN4-RPS16_ACTN4_chr19_39138546_ENST00000252699_RPS16_chr19_39924400_ENST00000339471_length(amino acids)=156AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKLLEPVLLLGKERFAGVDIRVRVKGGGHVAQIYGESQ
ELGAWRRWLWEGGLHSAPVPFNCVSFSQLSVSPSPKPWWPITRNMWMRLPRRRSKTSSSSMTGPCW

--------------------------------------------------------------
>1798_1798_3_ACTN4-RPS16_ACTN4_chr19_39138546_ENST00000252699_RPS16_chr19_39924400_ENST00000599539_length(transcript)=623nt_BP=238nt
GCGGCGGCGGCTCGGGCAGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCA
CGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGA
GGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGCTGCTGGAGCCAGTTCTGCTTCTCGGCAAGGA
GCGATTTGCTGGTGTAGACATCCGTGTCCGTGTAAAGGGTGGTGGTCACGTGGCCCAGATTTATGCTATCCGTCAGTCCATCTCCAAAGC
CCTGGTGGCCTATTACCAGAAATGTGAGTGAGCATGGGTCCTTCCCATGAGATGTGGATGAGGCTTCCAAGAAGGAGATCAAAGACATCC
TCATCCAGTATGACCGGACCCTGCTGGTAGCTGACCCTCGTCGCTGCGAGTCCAAAAAGTTTGGAGGCCCTGGTGCCCGCGCTCGCTACC
AGAAATCCTACCGATAAGCCCATCGTGACTCAAAACTCACTTGTATAATAAACAGTTTTTGAGGGATTTTAAAGTTTCAAGAA

>1798_1798_3_ACTN4-RPS16_ACTN4_chr19_39138546_ENST00000252699_RPS16_chr19_39924400_ENST00000599539_length(amino acids)=168AA_BP=1
MDSQRRGSATSRVRSYWMRMSLISFLEASSTSHGKDPCSLTFLVIGHQGFGDGLTDSINLGHVTTTLYTDTDVYTSKSLLAEKQNWLQQL
ALLLLPGRVQQQVPVPVVLLGHVVAHAAPAASAIARAAGAVLVRLVRRVVVHHSAASRSPTSLSAPASAPAPLPEPPP

--------------------------------------------------------------
>1798_1798_4_ACTN4-RPS16_ACTN4_chr19_39138546_ENST00000252699_RPS16_chr19_39924400_ENST00000601655_length(transcript)=585nt_BP=238nt
GCGGCGGCGGCTCGGGCAGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCA
CGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGA
GGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGCTGCTGGAGCCAGTTCTGCTTCTCGGCAAGGA
GCGATTTGCTGGTGTAGACATCCGTGTCCGTGTAAAGGGTGGTGGTCACGTGGCCCAGATTTATGCTATCCGTCAGTCCATCTCCAAAGC
CCTGGTGGCCTATTACCAGAAATATGTGGATGAGGCTTCCAAGAAGGAGATCAAAGACATCCTCATCCAGTATGACCGGACCCTGCTGGT
AGCTGACCCTCGTCGCTGCGAGTCCAAAAAGTTTGGAGGCCCTGGTGCCCGCGCTCGCTACCAGAAATCCTACCGATAAGCCCATCGTGA
CTCAAAACTCACTTGTATAATAAACAGTTTTTGAGGGATTTTAAA

>1798_1798_4_ACTN4-RPS16_ACTN4_chr19_39138546_ENST00000252699_RPS16_chr19_39924400_ENST00000601655_length(amino acids)=150AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKLLEPVLLLGKERFAGVDIRVRVKGGGHVAQIYAIRQ
SISKALVAYYQKYVDEASKKEIKDILIQYDRTLLVADPRRCESKKFGGPGARARYQKSYR

--------------------------------------------------------------
>1798_1798_5_ACTN4-RPS16_ACTN4_chr19_39138546_ENST00000390009_RPS16_chr19_39924400_ENST00000251453_length(transcript)=527nt_BP=170nt
GCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCA
TGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGCTGCTGGAGC
CAGTTCTGCTTCTCGGCAAGGAGCGATTTGCTGGTGTAGACATCCGTGTCCGTGTAAAGGGTGGTGGTCACGTGGCCCAGATTTATGCTA
TCCGTCAGTCCATCTCCAAAGCCCTGGTGGCCTATTACCAGAAATATGTGGATGAGGCTTCCAAGAAGGAGATCAAAGACATCCTCATCC
AGTATGACCGGACCCTGCTGGTAGCTGACCCTCGTCGCTGCGAGTCCAAAAAGTTTGGAGGCCCTGGTGCCCGCGCTCGCTACCAGAAAT
CCTACCGATAAGCCCATCGTGACTCAAAACTCACTTGTATAATAAACAGTTTTTGAGGGATTTTAAAGTTTCAAGAA

>1798_1798_5_ACTN4-RPS16_ACTN4_chr19_39138546_ENST00000390009_RPS16_chr19_39924400_ENST00000251453_length(amino acids)=155AA_BP=0
MGLSVGFLVASAGTRASKLFGLAATRVSYQQGPVILDEDVFDLLLGSLIHIFLVIGHQGFGDGLTDSINLGHVTTTLYTDTDVYTSKSLL
AEKQNWLQQLALLLLPGRVQQQVPVPVVLLGHVVAHAAPAASAIARAAGAVLVRLVRRVVVHHSA

--------------------------------------------------------------
>1798_1798_6_ACTN4-RPS16_ACTN4_chr19_39138546_ENST00000390009_RPS16_chr19_39924400_ENST00000339471_length(transcript)=622nt_BP=170nt
GCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCA
TGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGCTGCTGGAGC
CAGTTCTGCTTCTCGGCAAGGAGCGATTTGCTGGTGTAGACATCCGTGTCCGTGTAAAGGGTGGTGGTCACGTGGCCCAGATTTATGGTG
AGTCCCAGGAACTGGGCGCATGGAGGAGGTGGCTCTGGGAGGGAGGCCTTCACAGCGCTCCTGTACCCTTTAATTGTGTGTCTTTCTCAC
AGCTATCCGTCAGTCCATCTCCAAAGCCCTGGTGGCCTATTACCAGAAATATGTGGATGAGGCTTCCAAGAAGGAGATCAAAGACATCCT
CATCCAGTATGACCGGACCCTGCTGGTAGCTGACCCTCGTCGCTGCGAGTCCAAAAAGTTTGGAGGCCCTGGTGCCCGCGCTCGCTACCA
GAAATCCTACCGATAAGCCCATCGTGACTCAAAACTCACTTGTATAATAAACAGTTTTTGAGGGATTTTAAAGTTTCAAGAA

>1798_1798_6_ACTN4-RPS16_ACTN4_chr19_39138546_ENST00000390009_RPS16_chr19_39924400_ENST00000339471_length(amino acids)=156AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKLLEPVLLLGKERFAGVDIRVRVKGGGHVAQIYGESQ
ELGAWRRWLWEGGLHSAPVPFNCVSFSQLSVSPSPKPWWPITRNMWMRLPRRRSKTSSSSMTGPCW

--------------------------------------------------------------
>1798_1798_7_ACTN4-RPS16_ACTN4_chr19_39138546_ENST00000390009_RPS16_chr19_39924400_ENST00000599539_length(transcript)=555nt_BP=170nt
GCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCA
TGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGCTGCTGGAGC
CAGTTCTGCTTCTCGGCAAGGAGCGATTTGCTGGTGTAGACATCCGTGTCCGTGTAAAGGGTGGTGGTCACGTGGCCCAGATTTATGCTA
TCCGTCAGTCCATCTCCAAAGCCCTGGTGGCCTATTACCAGAAATGTGAGTGAGCATGGGTCCTTCCCATGAGATGTGGATGAGGCTTCC
AAGAAGGAGATCAAAGACATCCTCATCCAGTATGACCGGACCCTGCTGGTAGCTGACCCTCGTCGCTGCGAGTCCAAAAAGTTTGGAGGC
CCTGGTGCCCGCGCTCGCTACCAGAAATCCTACCGATAAGCCCATCGTGACTCAAAACTCACTTGTATAATAAACAGTTTTTGAGGGATT
TTAAAGTTTCAAGAA

>1798_1798_7_ACTN4-RPS16_ACTN4_chr19_39138546_ENST00000390009_RPS16_chr19_39924400_ENST00000599539_length(amino acids)=145AA_BP=1
MDSQRRGSATSRVRSYWMRMSLISFLEASSTSHGKDPCSLTFLVIGHQGFGDGLTDSINLGHVTTTLYTDTDVYTSKSLLAEKQNWLQQL
ALLLLPGRVQQQVPVPVVLLGHVVAHAAPAASAIARAAGAVLVRLVRRVVVHHSA

--------------------------------------------------------------
>1798_1798_8_ACTN4-RPS16_ACTN4_chr19_39138546_ENST00000390009_RPS16_chr19_39924400_ENST00000601655_length(transcript)=517nt_BP=170nt
GCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCA
TGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGCTGCTGGAGC
CAGTTCTGCTTCTCGGCAAGGAGCGATTTGCTGGTGTAGACATCCGTGTCCGTGTAAAGGGTGGTGGTCACGTGGCCCAGATTTATGCTA
TCCGTCAGTCCATCTCCAAAGCCCTGGTGGCCTATTACCAGAAATATGTGGATGAGGCTTCCAAGAAGGAGATCAAAGACATCCTCATCC
AGTATGACCGGACCCTGCTGGTAGCTGACCCTCGTCGCTGCGAGTCCAAAAAGTTTGGAGGCCCTGGTGCCCGCGCTCGCTACCAGAAAT
CCTACCGATAAGCCCATCGTGACTCAAAACTCACTTGTATAATAAACAGTTTTTGAGGGATTTTAAA

>1798_1798_8_ACTN4-RPS16_ACTN4_chr19_39138546_ENST00000390009_RPS16_chr19_39924400_ENST00000601655_length(amino acids)=150AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKLLEPVLLLGKERFAGVDIRVRVKGGGHVAQIYAIRQ
SISKALVAYYQKYVDEASKKEIKDILIQYDRTLLVADPRRCESKKFGGPGARARYQKSYR

--------------------------------------------------------------
>1798_1798_9_ACTN4-RPS16_ACTN4_chr19_39138546_ENST00000424234_RPS16_chr19_39924400_ENST00000251453_length(transcript)=578nt_BP=221nt
AGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGT
ACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGG
ACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGCTGCTGGAGCCAGTTCTGCTTCTCGGCAAGGAGCGATTTGCTGGTGTAG
ACATCCGTGTCCGTGTAAAGGGTGGTGGTCACGTGGCCCAGATTTATGCTATCCGTCAGTCCATCTCCAAAGCCCTGGTGGCCTATTACC
AGAAATATGTGGATGAGGCTTCCAAGAAGGAGATCAAAGACATCCTCATCCAGTATGACCGGACCCTGCTGGTAGCTGACCCTCGTCGCT
GCGAGTCCAAAAAGTTTGGAGGCCCTGGTGCCCGCGCTCGCTACCAGAAATCCTACCGATAAGCCCATCGTGACTCAAAACTCACTTGTA
TAATAAACAGTTTTTGAGGGATTTTAAAGTTTCAAGAA

>1798_1798_9_ACTN4-RPS16_ACTN4_chr19_39138546_ENST00000424234_RPS16_chr19_39924400_ENST00000251453_length(amino acids)=172AA_BP=0
MGLSVGFLVASAGTRASKLFGLAATRVSYQQGPVILDEDVFDLLLGSLIHIFLVIGHQGFGDGLTDSINLGHVTTTLYTDTDVYTSKSLL
AEKQNWLQQLALLLLPGRVQQQVPVPVVLLGHVVAHAAPAASAIARAAGAVLVRLVRRVVVHHSAASRSPTSLSAPASAPAP

--------------------------------------------------------------
>1798_1798_10_ACTN4-RPS16_ACTN4_chr19_39138546_ENST00000424234_RPS16_chr19_39924400_ENST00000339471_length(transcript)=673nt_BP=221nt
AGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGT
ACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGG
ACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGCTGCTGGAGCCAGTTCTGCTTCTCGGCAAGGAGCGATTTGCTGGTGTAG
ACATCCGTGTCCGTGTAAAGGGTGGTGGTCACGTGGCCCAGATTTATGGTGAGTCCCAGGAACTGGGCGCATGGAGGAGGTGGCTCTGGG
AGGGAGGCCTTCACAGCGCTCCTGTACCCTTTAATTGTGTGTCTTTCTCACAGCTATCCGTCAGTCCATCTCCAAAGCCCTGGTGGCCTA
TTACCAGAAATATGTGGATGAGGCTTCCAAGAAGGAGATCAAAGACATCCTCATCCAGTATGACCGGACCCTGCTGGTAGCTGACCCTCG
TCGCTGCGAGTCCAAAAAGTTTGGAGGCCCTGGTGCCCGCGCTCGCTACCAGAAATCCTACCGATAAGCCCATCGTGACTCAAAACTCAC
TTGTATAATAAACAGTTTTTGAGGGATTTTAAAGTTTCAAGAA

>1798_1798_10_ACTN4-RPS16_ACTN4_chr19_39138546_ENST00000424234_RPS16_chr19_39924400_ENST00000339471_length(amino acids)=156AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKLLEPVLLLGKERFAGVDIRVRVKGGGHVAQIYGESQ
ELGAWRRWLWEGGLHSAPVPFNCVSFSQLSVSPSPKPWWPITRNMWMRLPRRRSKTSSSSMTGPCW

--------------------------------------------------------------
>1798_1798_11_ACTN4-RPS16_ACTN4_chr19_39138546_ENST00000424234_RPS16_chr19_39924400_ENST00000599539_length(transcript)=606nt_BP=221nt
AGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGT
ACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGG
ACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGCTGCTGGAGCCAGTTCTGCTTCTCGGCAAGGAGCGATTTGCTGGTGTAG
ACATCCGTGTCCGTGTAAAGGGTGGTGGTCACGTGGCCCAGATTTATGCTATCCGTCAGTCCATCTCCAAAGCCCTGGTGGCCTATTACC
AGAAATGTGAGTGAGCATGGGTCCTTCCCATGAGATGTGGATGAGGCTTCCAAGAAGGAGATCAAAGACATCCTCATCCAGTATGACCGG
ACCCTGCTGGTAGCTGACCCTCGTCGCTGCGAGTCCAAAAAGTTTGGAGGCCCTGGTGCCCGCGCTCGCTACCAGAAATCCTACCGATAA
GCCCATCGTGACTCAAAACTCACTTGTATAATAAACAGTTTTTGAGGGATTTTAAAGTTTCAAGAA

>1798_1798_11_ACTN4-RPS16_ACTN4_chr19_39138546_ENST00000424234_RPS16_chr19_39924400_ENST00000599539_length(amino acids)=162AA_BP=1
MDSQRRGSATSRVRSYWMRMSLISFLEASSTSHGKDPCSLTFLVIGHQGFGDGLTDSINLGHVTTTLYTDTDVYTSKSLLAEKQNWLQQL
ALLLLPGRVQQQVPVPVVLLGHVVAHAAPAASAIARAAGAVLVRLVRRVVVHHSAASRSPTSLSAPASAPAP

--------------------------------------------------------------
>1798_1798_12_ACTN4-RPS16_ACTN4_chr19_39138546_ENST00000424234_RPS16_chr19_39924400_ENST00000601655_length(transcript)=568nt_BP=221nt
AGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGT
ACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGG
ACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGCTGCTGGAGCCAGTTCTGCTTCTCGGCAAGGAGCGATTTGCTGGTGTAG
ACATCCGTGTCCGTGTAAAGGGTGGTGGTCACGTGGCCCAGATTTATGCTATCCGTCAGTCCATCTCCAAAGCCCTGGTGGCCTATTACC
AGAAATATGTGGATGAGGCTTCCAAGAAGGAGATCAAAGACATCCTCATCCAGTATGACCGGACCCTGCTGGTAGCTGACCCTCGTCGCT
GCGAGTCCAAAAAGTTTGGAGGCCCTGGTGCCCGCGCTCGCTACCAGAAATCCTACCGATAAGCCCATCGTGACTCAAAACTCACTTGTA
TAATAAACAGTTTTTGAGGGATTTTAAA

>1798_1798_12_ACTN4-RPS16_ACTN4_chr19_39138546_ENST00000424234_RPS16_chr19_39924400_ENST00000601655_length(amino acids)=150AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKLLEPVLLLGKERFAGVDIRVRVKGGGHVAQIYAIRQ
SISKALVAYYQKYVDEASKKEIKDILIQYDRTLLVADPRRCESKKFGGPGARARYQKSYR

--------------------------------------------------------------
>1798_1798_13_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000252699_RPS16_chr19_39924401_ENST00000251453_length(transcript)=595nt_BP=238nt
GCGGCGGCGGCTCGGGCAGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCA
CGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGA
GGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGCTGCTGGAGCCAGTTCTGCTTCTCGGCAAGGA
GCGATTTGCTGGTGTAGACATCCGTGTCCGTGTAAAGGGTGGTGGTCACGTGGCCCAGATTTATGCTATCCGTCAGTCCATCTCCAAAGC
CCTGGTGGCCTATTACCAGAAATATGTGGATGAGGCTTCCAAGAAGGAGATCAAAGACATCCTCATCCAGTATGACCGGACCCTGCTGGT
AGCTGACCCTCGTCGCTGCGAGTCCAAAAAGTTTGGAGGCCCTGGTGCCCGCGCTCGCTACCAGAAATCCTACCGATAAGCCCATCGTGA
CTCAAAACTCACTTGTATAATAAACAGTTTTTGAGGGATTTTAAAGTTTCAAGAA

>1798_1798_13_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000252699_RPS16_chr19_39924401_ENST00000251453_length(amino acids)=178AA_BP=0
MGLSVGFLVASAGTRASKLFGLAATRVSYQQGPVILDEDVFDLLLGSLIHIFLVIGHQGFGDGLTDSINLGHVTTTLYTDTDVYTSKSLL
AEKQNWLQQLALLLLPGRVQQQVPVPVVLLGHVVAHAAPAASAIARAAGAVLVRLVRRVVVHHSAASRSPTSLSAPASAPAPLPEPPP

--------------------------------------------------------------
>1798_1798_14_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000252699_RPS16_chr19_39924401_ENST00000339471_length(transcript)=690nt_BP=238nt
GCGGCGGCGGCTCGGGCAGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCA
CGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGA
GGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGCTGCTGGAGCCAGTTCTGCTTCTCGGCAAGGA
GCGATTTGCTGGTGTAGACATCCGTGTCCGTGTAAAGGGTGGTGGTCACGTGGCCCAGATTTATGGTGAGTCCCAGGAACTGGGCGCATG
GAGGAGGTGGCTCTGGGAGGGAGGCCTTCACAGCGCTCCTGTACCCTTTAATTGTGTGTCTTTCTCACAGCTATCCGTCAGTCCATCTCC
AAAGCCCTGGTGGCCTATTACCAGAAATATGTGGATGAGGCTTCCAAGAAGGAGATCAAAGACATCCTCATCCAGTATGACCGGACCCTG
CTGGTAGCTGACCCTCGTCGCTGCGAGTCCAAAAAGTTTGGAGGCCCTGGTGCCCGCGCTCGCTACCAGAAATCCTACCGATAAGCCCAT
CGTGACTCAAAACTCACTTGTATAATAAACAGTTTTTGAGGGATTTTAAAGTTTCAAGAA

>1798_1798_14_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000252699_RPS16_chr19_39924401_ENST00000339471_length(amino acids)=156AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKLLEPVLLLGKERFAGVDIRVRVKGGGHVAQIYGESQ
ELGAWRRWLWEGGLHSAPVPFNCVSFSQLSVSPSPKPWWPITRNMWMRLPRRRSKTSSSSMTGPCW

--------------------------------------------------------------
>1798_1798_15_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000252699_RPS16_chr19_39924401_ENST00000599539_length(transcript)=623nt_BP=238nt
GCGGCGGCGGCTCGGGCAGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCA
CGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGA
GGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGCTGCTGGAGCCAGTTCTGCTTCTCGGCAAGGA
GCGATTTGCTGGTGTAGACATCCGTGTCCGTGTAAAGGGTGGTGGTCACGTGGCCCAGATTTATGCTATCCGTCAGTCCATCTCCAAAGC
CCTGGTGGCCTATTACCAGAAATGTGAGTGAGCATGGGTCCTTCCCATGAGATGTGGATGAGGCTTCCAAGAAGGAGATCAAAGACATCC
TCATCCAGTATGACCGGACCCTGCTGGTAGCTGACCCTCGTCGCTGCGAGTCCAAAAAGTTTGGAGGCCCTGGTGCCCGCGCTCGCTACC
AGAAATCCTACCGATAAGCCCATCGTGACTCAAAACTCACTTGTATAATAAACAGTTTTTGAGGGATTTTAAAGTTTCAAGAA

>1798_1798_15_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000252699_RPS16_chr19_39924401_ENST00000599539_length(amino acids)=168AA_BP=1
MDSQRRGSATSRVRSYWMRMSLISFLEASSTSHGKDPCSLTFLVIGHQGFGDGLTDSINLGHVTTTLYTDTDVYTSKSLLAEKQNWLQQL
ALLLLPGRVQQQVPVPVVLLGHVVAHAAPAASAIARAAGAVLVRLVRRVVVHHSAASRSPTSLSAPASAPAPLPEPPP

--------------------------------------------------------------
>1798_1798_16_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000252699_RPS16_chr19_39924401_ENST00000601655_length(transcript)=585nt_BP=238nt
GCGGCGGCGGCTCGGGCAGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCA
CGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGA
GGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGCTGCTGGAGCCAGTTCTGCTTCTCGGCAAGGA
GCGATTTGCTGGTGTAGACATCCGTGTCCGTGTAAAGGGTGGTGGTCACGTGGCCCAGATTTATGCTATCCGTCAGTCCATCTCCAAAGC
CCTGGTGGCCTATTACCAGAAATATGTGGATGAGGCTTCCAAGAAGGAGATCAAAGACATCCTCATCCAGTATGACCGGACCCTGCTGGT
AGCTGACCCTCGTCGCTGCGAGTCCAAAAAGTTTGGAGGCCCTGGTGCCCGCGCTCGCTACCAGAAATCCTACCGATAAGCCCATCGTGA
CTCAAAACTCACTTGTATAATAAACAGTTTTTGAGGGATTTTAAA

>1798_1798_16_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000252699_RPS16_chr19_39924401_ENST00000601655_length(amino acids)=150AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKLLEPVLLLGKERFAGVDIRVRVKGGGHVAQIYAIRQ
SISKALVAYYQKYVDEASKKEIKDILIQYDRTLLVADPRRCESKKFGGPGARARYQKSYR

--------------------------------------------------------------
>1798_1798_17_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000252699_RPS16_chr19_39926348_ENST00000251453_length(transcript)=697nt_BP=238nt
GCGGCGGCGGCTCGGGCAGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCA
CGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGA
GGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGAAGACAGCGACAGCTGTGGCGCACTGCAAACG
CGGCAATGGTCTCATCAAGGTGAACGGGCGGCCCCTGGAGATGATTGAGCCGCGCACGCTACAGTACAAGCTGCTGGAGCCAGTTCTGCT
TCTCGGCAAGGAGCGATTTGCTGGTGTAGACATCCGTGTCCGTGTAAAGGGTGGTGGTCACGTGGCCCAGATTTATGCTATCCGTCAGTC
CATCTCCAAAGCCCTGGTGGCCTATTACCAGAAATATGTGGATGAGGCTTCCAAGAAGGAGATCAAAGACATCCTCATCCAGTATGACCG
GACCCTGCTGGTAGCTGACCCTCGTCGCTGCGAGTCCAAAAAGTTTGGAGGCCCTGGTGCCCGCGCTCGCTACCAGAAATCCTACCGATA
AGCCCATCGTGACTCAAAACTCACTTGTATAATAAACAGTTTTTGAGGGATTTTAAAGTTTCAAGAA

>1798_1798_17_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000252699_RPS16_chr19_39926348_ENST00000251453_length(amino acids)=184AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKKTATAVAHCKRGNGLIKVNGRPLEMIEPRTLQYKLL
EPVLLLGKERFAGVDIRVRVKGGGHVAQIYAIRQSISKALVAYYQKYVDEASKKEIKDILIQYDRTLLVADPRRCESKKFGGPGARARYQ
KSYR

--------------------------------------------------------------
>1798_1798_18_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000252699_RPS16_chr19_39926348_ENST00000339471_length(transcript)=792nt_BP=238nt
GCGGCGGCGGCTCGGGCAGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCA
CGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGA
GGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGAAGACAGCGACAGCTGTGGCGCACTGCAAACG
CGGCAATGGTCTCATCAAGGTGAACGGGCGGCCCCTGGAGATGATTGAGCCGCGCACGCTACAGTACAAGCTGCTGGAGCCAGTTCTGCT
TCTCGGCAAGGAGCGATTTGCTGGTGTAGACATCCGTGTCCGTGTAAAGGGTGGTGGTCACGTGGCCCAGATTTATGGTGAGTCCCAGGA
ACTGGGCGCATGGAGGAGGTGGCTCTGGGAGGGAGGCCTTCACAGCGCTCCTGTACCCTTTAATTGTGTGTCTTTCTCACAGCTATCCGT
CAGTCCATCTCCAAAGCCCTGGTGGCCTATTACCAGAAATATGTGGATGAGGCTTCCAAGAAGGAGATCAAAGACATCCTCATCCAGTAT
GACCGGACCCTGCTGGTAGCTGACCCTCGTCGCTGCGAGTCCAAAAAGTTTGGAGGCCCTGGTGCCCGCGCTCGCTACCAGAAATCCTAC
CGATAAGCCCATCGTGACTCAAAACTCACTTGTATAATAAACAGTTTTTGAGGGATTTTAAAGTTTCAAGAA

>1798_1798_18_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000252699_RPS16_chr19_39926348_ENST00000339471_length(amino acids)=190AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKKTATAVAHCKRGNGLIKVNGRPLEMIEPRTLQYKLL
EPVLLLGKERFAGVDIRVRVKGGGHVAQIYGESQELGAWRRWLWEGGLHSAPVPFNCVSFSQLSVSPSPKPWWPITRNMWMRLPRRRSKT
SSSSMTGPCW

--------------------------------------------------------------
>1798_1798_19_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000252699_RPS16_chr19_39926348_ENST00000599539_length(transcript)=725nt_BP=238nt
GCGGCGGCGGCTCGGGCAGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCA
CGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGA
GGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGAAGACAGCGACAGCTGTGGCGCACTGCAAACG
CGGCAATGGTCTCATCAAGGTGAACGGGCGGCCCCTGGAGATGATTGAGCCGCGCACGCTACAGTACAAGCTGCTGGAGCCAGTTCTGCT
TCTCGGCAAGGAGCGATTTGCTGGTGTAGACATCCGTGTCCGTGTAAAGGGTGGTGGTCACGTGGCCCAGATTTATGCTATCCGTCAGTC
CATCTCCAAAGCCCTGGTGGCCTATTACCAGAAATGTGAGTGAGCATGGGTCCTTCCCATGAGATGTGGATGAGGCTTCCAAGAAGGAGA
TCAAAGACATCCTCATCCAGTATGACCGGACCCTGCTGGTAGCTGACCCTCGTCGCTGCGAGTCCAAAAAGTTTGGAGGCCCTGGTGCCC
GCGCTCGCTACCAGAAATCCTACCGATAAGCCCATCGTGACTCAAAACTCACTTGTATAATAAACAGTTTTTGAGGGATTTTAAAGTTTC
AAGAA

>1798_1798_19_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000252699_RPS16_chr19_39926348_ENST00000599539_length(amino acids)=138AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKKTATAVAHCKRGNGLIKVNGRPLEMIEPRTLQYKLL
EPVLLLGKERFAGVDIRVRVKGGGHVAQIYAIRQSISKALVAYYQKCE

--------------------------------------------------------------
>1798_1798_20_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000252699_RPS16_chr19_39926348_ENST00000601655_length(transcript)=636nt_BP=238nt
GCGGCGGCGGCTCGGGCAGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCA
CGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGA
GGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGAAGACAGCGACAGCTGTGGCGCACTGCAAACG
CGGCAATGGTCTCATCAAGCTGCTGGAGCCAGTTCTGCTTCTCGGCAAGGAGCGATTTGCTGGTGTAGACATCCGTGTCCGTGTAAAGGG
TGGTGGTCACGTGGCCCAGATTTATGCTATCCGTCAGTCCATCTCCAAAGCCCTGGTGGCCTATTACCAGAAATATGTGGATGAGGCTTC
CAAGAAGGAGATCAAAGACATCCTCATCCAGTATGACCGGACCCTGCTGGTAGCTGACCCTCGTCGCTGCGAGTCCAAAAAGTTTGGAGG
CCCTGGTGCCCGCGCTCGCTACCAGAAATCCTACCGATAAGCCCATCGTGACTCAAAACTCACTTGTATAATAAACAGTTTTTGAGGGAT
TTTAAA

>1798_1798_20_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000252699_RPS16_chr19_39926348_ENST00000601655_length(amino acids)=167AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKKTATAVAHCKRGNGLIKLLEPVLLLGKERFAGVDIR
VRVKGGGHVAQIYAIRQSISKALVAYYQKYVDEASKKEIKDILIQYDRTLLVADPRRCESKKFGGPGARARYQKSYR

--------------------------------------------------------------
>1798_1798_21_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000390009_RPS16_chr19_39924401_ENST00000251453_length(transcript)=527nt_BP=170nt
GCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCA
TGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGCTGCTGGAGC
CAGTTCTGCTTCTCGGCAAGGAGCGATTTGCTGGTGTAGACATCCGTGTCCGTGTAAAGGGTGGTGGTCACGTGGCCCAGATTTATGCTA
TCCGTCAGTCCATCTCCAAAGCCCTGGTGGCCTATTACCAGAAATATGTGGATGAGGCTTCCAAGAAGGAGATCAAAGACATCCTCATCC
AGTATGACCGGACCCTGCTGGTAGCTGACCCTCGTCGCTGCGAGTCCAAAAAGTTTGGAGGCCCTGGTGCCCGCGCTCGCTACCAGAAAT
CCTACCGATAAGCCCATCGTGACTCAAAACTCACTTGTATAATAAACAGTTTTTGAGGGATTTTAAAGTTTCAAGAA

>1798_1798_21_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000390009_RPS16_chr19_39924401_ENST00000251453_length(amino acids)=155AA_BP=0
MGLSVGFLVASAGTRASKLFGLAATRVSYQQGPVILDEDVFDLLLGSLIHIFLVIGHQGFGDGLTDSINLGHVTTTLYTDTDVYTSKSLL
AEKQNWLQQLALLLLPGRVQQQVPVPVVLLGHVVAHAAPAASAIARAAGAVLVRLVRRVVVHHSA

--------------------------------------------------------------
>1798_1798_22_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000390009_RPS16_chr19_39924401_ENST00000339471_length(transcript)=622nt_BP=170nt
GCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCA
TGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGCTGCTGGAGC
CAGTTCTGCTTCTCGGCAAGGAGCGATTTGCTGGTGTAGACATCCGTGTCCGTGTAAAGGGTGGTGGTCACGTGGCCCAGATTTATGGTG
AGTCCCAGGAACTGGGCGCATGGAGGAGGTGGCTCTGGGAGGGAGGCCTTCACAGCGCTCCTGTACCCTTTAATTGTGTGTCTTTCTCAC
AGCTATCCGTCAGTCCATCTCCAAAGCCCTGGTGGCCTATTACCAGAAATATGTGGATGAGGCTTCCAAGAAGGAGATCAAAGACATCCT
CATCCAGTATGACCGGACCCTGCTGGTAGCTGACCCTCGTCGCTGCGAGTCCAAAAAGTTTGGAGGCCCTGGTGCCCGCGCTCGCTACCA
GAAATCCTACCGATAAGCCCATCGTGACTCAAAACTCACTTGTATAATAAACAGTTTTTGAGGGATTTTAAAGTTTCAAGAA

>1798_1798_22_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000390009_RPS16_chr19_39924401_ENST00000339471_length(amino acids)=156AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKLLEPVLLLGKERFAGVDIRVRVKGGGHVAQIYGESQ
ELGAWRRWLWEGGLHSAPVPFNCVSFSQLSVSPSPKPWWPITRNMWMRLPRRRSKTSSSSMTGPCW

--------------------------------------------------------------
>1798_1798_23_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000390009_RPS16_chr19_39924401_ENST00000599539_length(transcript)=555nt_BP=170nt
GCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCA
TGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGCTGCTGGAGC
CAGTTCTGCTTCTCGGCAAGGAGCGATTTGCTGGTGTAGACATCCGTGTCCGTGTAAAGGGTGGTGGTCACGTGGCCCAGATTTATGCTA
TCCGTCAGTCCATCTCCAAAGCCCTGGTGGCCTATTACCAGAAATGTGAGTGAGCATGGGTCCTTCCCATGAGATGTGGATGAGGCTTCC
AAGAAGGAGATCAAAGACATCCTCATCCAGTATGACCGGACCCTGCTGGTAGCTGACCCTCGTCGCTGCGAGTCCAAAAAGTTTGGAGGC
CCTGGTGCCCGCGCTCGCTACCAGAAATCCTACCGATAAGCCCATCGTGACTCAAAACTCACTTGTATAATAAACAGTTTTTGAGGGATT
TTAAAGTTTCAAGAA

>1798_1798_23_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000390009_RPS16_chr19_39924401_ENST00000599539_length(amino acids)=145AA_BP=1
MDSQRRGSATSRVRSYWMRMSLISFLEASSTSHGKDPCSLTFLVIGHQGFGDGLTDSINLGHVTTTLYTDTDVYTSKSLLAEKQNWLQQL
ALLLLPGRVQQQVPVPVVLLGHVVAHAAPAASAIARAAGAVLVRLVRRVVVHHSA

--------------------------------------------------------------
>1798_1798_24_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000390009_RPS16_chr19_39924401_ENST00000601655_length(transcript)=517nt_BP=170nt
GCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCA
TGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGCTGCTGGAGC
CAGTTCTGCTTCTCGGCAAGGAGCGATTTGCTGGTGTAGACATCCGTGTCCGTGTAAAGGGTGGTGGTCACGTGGCCCAGATTTATGCTA
TCCGTCAGTCCATCTCCAAAGCCCTGGTGGCCTATTACCAGAAATATGTGGATGAGGCTTCCAAGAAGGAGATCAAAGACATCCTCATCC
AGTATGACCGGACCCTGCTGGTAGCTGACCCTCGTCGCTGCGAGTCCAAAAAGTTTGGAGGCCCTGGTGCCCGCGCTCGCTACCAGAAAT
CCTACCGATAAGCCCATCGTGACTCAAAACTCACTTGTATAATAAACAGTTTTTGAGGGATTTTAAA

>1798_1798_24_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000390009_RPS16_chr19_39924401_ENST00000601655_length(amino acids)=150AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKLLEPVLLLGKERFAGVDIRVRVKGGGHVAQIYAIRQ
SISKALVAYYQKYVDEASKKEIKDILIQYDRTLLVADPRRCESKKFGGPGARARYQKSYR

--------------------------------------------------------------
>1798_1798_25_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000390009_RPS16_chr19_39926348_ENST00000251453_length(transcript)=629nt_BP=170nt
GCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCA
TGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGAAGACAGCGA
CAGCTGTGGCGCACTGCAAACGCGGCAATGGTCTCATCAAGGTGAACGGGCGGCCCCTGGAGATGATTGAGCCGCGCACGCTACAGTACA
AGCTGCTGGAGCCAGTTCTGCTTCTCGGCAAGGAGCGATTTGCTGGTGTAGACATCCGTGTCCGTGTAAAGGGTGGTGGTCACGTGGCCC
AGATTTATGCTATCCGTCAGTCCATCTCCAAAGCCCTGGTGGCCTATTACCAGAAATATGTGGATGAGGCTTCCAAGAAGGAGATCAAAG
ACATCCTCATCCAGTATGACCGGACCCTGCTGGTAGCTGACCCTCGTCGCTGCGAGTCCAAAAAGTTTGGAGGCCCTGGTGCCCGCGCTC
GCTACCAGAAATCCTACCGATAAGCCCATCGTGACTCAAAACTCACTTGTATAATAAACAGTTTTTGAGGGATTTTAAAGTTTCAAGAA

>1798_1798_25_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000390009_RPS16_chr19_39926348_ENST00000251453_length(amino acids)=184AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKKTATAVAHCKRGNGLIKVNGRPLEMIEPRTLQYKLL
EPVLLLGKERFAGVDIRVRVKGGGHVAQIYAIRQSISKALVAYYQKYVDEASKKEIKDILIQYDRTLLVADPRRCESKKFGGPGARARYQ
KSYR

--------------------------------------------------------------
>1798_1798_26_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000390009_RPS16_chr19_39926348_ENST00000339471_length(transcript)=724nt_BP=170nt
GCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCA
TGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGAAGACAGCGA
CAGCTGTGGCGCACTGCAAACGCGGCAATGGTCTCATCAAGGTGAACGGGCGGCCCCTGGAGATGATTGAGCCGCGCACGCTACAGTACA
AGCTGCTGGAGCCAGTTCTGCTTCTCGGCAAGGAGCGATTTGCTGGTGTAGACATCCGTGTCCGTGTAAAGGGTGGTGGTCACGTGGCCC
AGATTTATGGTGAGTCCCAGGAACTGGGCGCATGGAGGAGGTGGCTCTGGGAGGGAGGCCTTCACAGCGCTCCTGTACCCTTTAATTGTG
TGTCTTTCTCACAGCTATCCGTCAGTCCATCTCCAAAGCCCTGGTGGCCTATTACCAGAAATATGTGGATGAGGCTTCCAAGAAGGAGAT
CAAAGACATCCTCATCCAGTATGACCGGACCCTGCTGGTAGCTGACCCTCGTCGCTGCGAGTCCAAAAAGTTTGGAGGCCCTGGTGCCCG
CGCTCGCTACCAGAAATCCTACCGATAAGCCCATCGTGACTCAAAACTCACTTGTATAATAAACAGTTTTTGAGGGATTTTAAAGTTTCA
AGAA

>1798_1798_26_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000390009_RPS16_chr19_39926348_ENST00000339471_length(amino acids)=190AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKKTATAVAHCKRGNGLIKVNGRPLEMIEPRTLQYKLL
EPVLLLGKERFAGVDIRVRVKGGGHVAQIYGESQELGAWRRWLWEGGLHSAPVPFNCVSFSQLSVSPSPKPWWPITRNMWMRLPRRRSKT
SSSSMTGPCW

--------------------------------------------------------------
>1798_1798_27_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000390009_RPS16_chr19_39926348_ENST00000599539_length(transcript)=657nt_BP=170nt
GCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCA
TGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGAAGACAGCGA
CAGCTGTGGCGCACTGCAAACGCGGCAATGGTCTCATCAAGGTGAACGGGCGGCCCCTGGAGATGATTGAGCCGCGCACGCTACAGTACA
AGCTGCTGGAGCCAGTTCTGCTTCTCGGCAAGGAGCGATTTGCTGGTGTAGACATCCGTGTCCGTGTAAAGGGTGGTGGTCACGTGGCCC
AGATTTATGCTATCCGTCAGTCCATCTCCAAAGCCCTGGTGGCCTATTACCAGAAATGTGAGTGAGCATGGGTCCTTCCCATGAGATGTG
GATGAGGCTTCCAAGAAGGAGATCAAAGACATCCTCATCCAGTATGACCGGACCCTGCTGGTAGCTGACCCTCGTCGCTGCGAGTCCAAA
AAGTTTGGAGGCCCTGGTGCCCGCGCTCGCTACCAGAAATCCTACCGATAAGCCCATCGTGACTCAAAACTCACTTGTATAATAAACAGT
TTTTGAGGGATTTTAAAGTTTCAAGAA

>1798_1798_27_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000390009_RPS16_chr19_39926348_ENST00000599539_length(amino acids)=138AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKKTATAVAHCKRGNGLIKVNGRPLEMIEPRTLQYKLL
EPVLLLGKERFAGVDIRVRVKGGGHVAQIYAIRQSISKALVAYYQKCE

--------------------------------------------------------------
>1798_1798_28_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000390009_RPS16_chr19_39926348_ENST00000601655_length(transcript)=568nt_BP=170nt
GCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGTACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCA
TGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGGACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGAAGACAGCGA
CAGCTGTGGCGCACTGCAAACGCGGCAATGGTCTCATCAAGCTGCTGGAGCCAGTTCTGCTTCTCGGCAAGGAGCGATTTGCTGGTGTAG
ACATCCGTGTCCGTGTAAAGGGTGGTGGTCACGTGGCCCAGATTTATGCTATCCGTCAGTCCATCTCCAAAGCCCTGGTGGCCTATTACC
AGAAATATGTGGATGAGGCTTCCAAGAAGGAGATCAAAGACATCCTCATCCAGTATGACCGGACCCTGCTGGTAGCTGACCCTCGTCGCT
GCGAGTCCAAAAAGTTTGGAGGCCCTGGTGCCCGCGCTCGCTACCAGAAATCCTACCGATAAGCCCATCGTGACTCAAAACTCACTTGTA
TAATAAACAGTTTTTGAGGGATTTTAAA

>1798_1798_28_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000390009_RPS16_chr19_39926348_ENST00000601655_length(amino acids)=167AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKKTATAVAHCKRGNGLIKLLEPVLLLGKERFAGVDIR
VRVKGGGHVAQIYAIRQSISKALVAYYQKYVDEASKKEIKDILIQYDRTLLVADPRRCESKKFGGPGARARYQKSYR

--------------------------------------------------------------
>1798_1798_29_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000424234_RPS16_chr19_39924401_ENST00000251453_length(transcript)=578nt_BP=221nt
AGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGT
ACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGG
ACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGCTGCTGGAGCCAGTTCTGCTTCTCGGCAAGGAGCGATTTGCTGGTGTAG
ACATCCGTGTCCGTGTAAAGGGTGGTGGTCACGTGGCCCAGATTTATGCTATCCGTCAGTCCATCTCCAAAGCCCTGGTGGCCTATTACC
AGAAATATGTGGATGAGGCTTCCAAGAAGGAGATCAAAGACATCCTCATCCAGTATGACCGGACCCTGCTGGTAGCTGACCCTCGTCGCT
GCGAGTCCAAAAAGTTTGGAGGCCCTGGTGCCCGCGCTCGCTACCAGAAATCCTACCGATAAGCCCATCGTGACTCAAAACTCACTTGTA
TAATAAACAGTTTTTGAGGGATTTTAAAGTTTCAAGAA

>1798_1798_29_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000424234_RPS16_chr19_39924401_ENST00000251453_length(amino acids)=172AA_BP=0
MGLSVGFLVASAGTRASKLFGLAATRVSYQQGPVILDEDVFDLLLGSLIHIFLVIGHQGFGDGLTDSINLGHVTTTLYTDTDVYTSKSLL
AEKQNWLQQLALLLLPGRVQQQVPVPVVLLGHVVAHAAPAASAIARAAGAVLVRLVRRVVVHHSAASRSPTSLSAPASAPAP

--------------------------------------------------------------
>1798_1798_30_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000424234_RPS16_chr19_39924401_ENST00000339471_length(transcript)=673nt_BP=221nt
AGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGT
ACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGG
ACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGCTGCTGGAGCCAGTTCTGCTTCTCGGCAAGGAGCGATTTGCTGGTGTAG
ACATCCGTGTCCGTGTAAAGGGTGGTGGTCACGTGGCCCAGATTTATGGTGAGTCCCAGGAACTGGGCGCATGGAGGAGGTGGCTCTGGG
AGGGAGGCCTTCACAGCGCTCCTGTACCCTTTAATTGTGTGTCTTTCTCACAGCTATCCGTCAGTCCATCTCCAAAGCCCTGGTGGCCTA
TTACCAGAAATATGTGGATGAGGCTTCCAAGAAGGAGATCAAAGACATCCTCATCCAGTATGACCGGACCCTGCTGGTAGCTGACCCTCG
TCGCTGCGAGTCCAAAAAGTTTGGAGGCCCTGGTGCCCGCGCTCGCTACCAGAAATCCTACCGATAAGCCCATCGTGACTCAAAACTCAC
TTGTATAATAAACAGTTTTTGAGGGATTTTAAAGTTTCAAGAA

>1798_1798_30_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000424234_RPS16_chr19_39924401_ENST00000339471_length(amino acids)=156AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKLLEPVLLLGKERFAGVDIRVRVKGGGHVAQIYGESQ
ELGAWRRWLWEGGLHSAPVPFNCVSFSQLSVSPSPKPWWPITRNMWMRLPRRRSKTSSSSMTGPCW

--------------------------------------------------------------
>1798_1798_31_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000424234_RPS16_chr19_39924401_ENST00000599539_length(transcript)=606nt_BP=221nt
AGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGT
ACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGG
ACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGCTGCTGGAGCCAGTTCTGCTTCTCGGCAAGGAGCGATTTGCTGGTGTAG
ACATCCGTGTCCGTGTAAAGGGTGGTGGTCACGTGGCCCAGATTTATGCTATCCGTCAGTCCATCTCCAAAGCCCTGGTGGCCTATTACC
AGAAATGTGAGTGAGCATGGGTCCTTCCCATGAGATGTGGATGAGGCTTCCAAGAAGGAGATCAAAGACATCCTCATCCAGTATGACCGG
ACCCTGCTGGTAGCTGACCCTCGTCGCTGCGAGTCCAAAAAGTTTGGAGGCCCTGGTGCCCGCGCTCGCTACCAGAAATCCTACCGATAA
GCCCATCGTGACTCAAAACTCACTTGTATAATAAACAGTTTTTGAGGGATTTTAAAGTTTCAAGAA

>1798_1798_31_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000424234_RPS16_chr19_39924401_ENST00000599539_length(amino acids)=162AA_BP=1
MDSQRRGSATSRVRSYWMRMSLISFLEASSTSHGKDPCSLTFLVIGHQGFGDGLTDSINLGHVTTTLYTDTDVYTSKSLLAEKQNWLQQL
ALLLLPGRVQQQVPVPVVLLGHVVAHAAPAASAIARAAGAVLVRLVRRVVVHHSAASRSPTSLSAPASAPAP

--------------------------------------------------------------
>1798_1798_32_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000424234_RPS16_chr19_39924401_ENST00000601655_length(transcript)=568nt_BP=221nt
AGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGT
ACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGG
ACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGCTGCTGGAGCCAGTTCTGCTTCTCGGCAAGGAGCGATTTGCTGGTGTAG
ACATCCGTGTCCGTGTAAAGGGTGGTGGTCACGTGGCCCAGATTTATGCTATCCGTCAGTCCATCTCCAAAGCCCTGGTGGCCTATTACC
AGAAATATGTGGATGAGGCTTCCAAGAAGGAGATCAAAGACATCCTCATCCAGTATGACCGGACCCTGCTGGTAGCTGACCCTCGTCGCT
GCGAGTCCAAAAAGTTTGGAGGCCCTGGTGCCCGCGCTCGCTACCAGAAATCCTACCGATAAGCCCATCGTGACTCAAAACTCACTTGTA
TAATAAACAGTTTTTGAGGGATTTTAAA

>1798_1798_32_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000424234_RPS16_chr19_39924401_ENST00000601655_length(amino acids)=150AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKLLEPVLLLGKERFAGVDIRVRVKGGGHVAQIYAIRQ
SISKALVAYYQKYVDEASKKEIKDILIQYDRTLLVADPRRCESKKFGGPGARARYQKSYR

--------------------------------------------------------------
>1798_1798_33_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000424234_RPS16_chr19_39926348_ENST00000251453_length(transcript)=680nt_BP=221nt
AGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGT
ACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGG
ACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGAAGACAGCGACAGCTGTGGCGCACTGCAAACGCGGCAATGGTCTCATCA
AGGTGAACGGGCGGCCCCTGGAGATGATTGAGCCGCGCACGCTACAGTACAAGCTGCTGGAGCCAGTTCTGCTTCTCGGCAAGGAGCGAT
TTGCTGGTGTAGACATCCGTGTCCGTGTAAAGGGTGGTGGTCACGTGGCCCAGATTTATGCTATCCGTCAGTCCATCTCCAAAGCCCTGG
TGGCCTATTACCAGAAATATGTGGATGAGGCTTCCAAGAAGGAGATCAAAGACATCCTCATCCAGTATGACCGGACCCTGCTGGTAGCTG
ACCCTCGTCGCTGCGAGTCCAAAAAGTTTGGAGGCCCTGGTGCCCGCGCTCGCTACCAGAAATCCTACCGATAAGCCCATCGTGACTCAA
AACTCACTTGTATAATAAACAGTTTTTGAGGGATTTTAAAGTTTCAAGAA

>1798_1798_33_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000424234_RPS16_chr19_39926348_ENST00000251453_length(amino acids)=184AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKKTATAVAHCKRGNGLIKVNGRPLEMIEPRTLQYKLL
EPVLLLGKERFAGVDIRVRVKGGGHVAQIYAIRQSISKALVAYYQKYVDEASKKEIKDILIQYDRTLLVADPRRCESKKFGGPGARARYQ
KSYR

--------------------------------------------------------------
>1798_1798_34_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000424234_RPS16_chr19_39926348_ENST00000339471_length(transcript)=775nt_BP=221nt
AGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGT
ACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGG
ACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGAAGACAGCGACAGCTGTGGCGCACTGCAAACGCGGCAATGGTCTCATCA
AGGTGAACGGGCGGCCCCTGGAGATGATTGAGCCGCGCACGCTACAGTACAAGCTGCTGGAGCCAGTTCTGCTTCTCGGCAAGGAGCGAT
TTGCTGGTGTAGACATCCGTGTCCGTGTAAAGGGTGGTGGTCACGTGGCCCAGATTTATGGTGAGTCCCAGGAACTGGGCGCATGGAGGA
GGTGGCTCTGGGAGGGAGGCCTTCACAGCGCTCCTGTACCCTTTAATTGTGTGTCTTTCTCACAGCTATCCGTCAGTCCATCTCCAAAGC
CCTGGTGGCCTATTACCAGAAATATGTGGATGAGGCTTCCAAGAAGGAGATCAAAGACATCCTCATCCAGTATGACCGGACCCTGCTGGT
AGCTGACCCTCGTCGCTGCGAGTCCAAAAAGTTTGGAGGCCCTGGTGCCCGCGCTCGCTACCAGAAATCCTACCGATAAGCCCATCGTGA
CTCAAAACTCACTTGTATAATAAACAGTTTTTGAGGGATTTTAAAGTTTCAAGAA

>1798_1798_34_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000424234_RPS16_chr19_39926348_ENST00000339471_length(amino acids)=190AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKKTATAVAHCKRGNGLIKVNGRPLEMIEPRTLQYKLL
EPVLLLGKERFAGVDIRVRVKGGGHVAQIYGESQELGAWRRWLWEGGLHSAPVPFNCVSFSQLSVSPSPKPWWPITRNMWMRLPRRRSKT
SSSSMTGPCW

--------------------------------------------------------------
>1798_1798_35_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000424234_RPS16_chr19_39926348_ENST00000599539_length(transcript)=708nt_BP=221nt
AGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGT
ACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGG
ACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGAAGACAGCGACAGCTGTGGCGCACTGCAAACGCGGCAATGGTCTCATCA
AGGTGAACGGGCGGCCCCTGGAGATGATTGAGCCGCGCACGCTACAGTACAAGCTGCTGGAGCCAGTTCTGCTTCTCGGCAAGGAGCGAT
TTGCTGGTGTAGACATCCGTGTCCGTGTAAAGGGTGGTGGTCACGTGGCCCAGATTTATGCTATCCGTCAGTCCATCTCCAAAGCCCTGG
TGGCCTATTACCAGAAATGTGAGTGAGCATGGGTCCTTCCCATGAGATGTGGATGAGGCTTCCAAGAAGGAGATCAAAGACATCCTCATC
CAGTATGACCGGACCCTGCTGGTAGCTGACCCTCGTCGCTGCGAGTCCAAAAAGTTTGGAGGCCCTGGTGCCCGCGCTCGCTACCAGAAA
TCCTACCGATAAGCCCATCGTGACTCAAAACTCACTTGTATAATAAACAGTTTTTGAGGGATTTTAAAGTTTCAAGAA

>1798_1798_35_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000424234_RPS16_chr19_39926348_ENST00000599539_length(amino acids)=138AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKKTATAVAHCKRGNGLIKVNGRPLEMIEPRTLQYKLL
EPVLLLGKERFAGVDIRVRVKGGGHVAQIYAIRQSISKALVAYYQKCE

--------------------------------------------------------------
>1798_1798_36_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000424234_RPS16_chr19_39926348_ENST00000601655_length(transcript)=619nt_BP=221nt
AGAGGGGCGGGAGCTGAGGCGGGAGCGGACAGGCTGGTGGGCGAGCGAGAGGCGGCGGAATGGTGGACTACCACGCGGCGAACCAGTCGT
ACCAGTACGGCCCCAGCAGCGCGGGCAATGGCGCTGGCGGCGGGGGCAGCATGGGCGACTACATGGCCCAGGAGGACGACTGGGACCGGG
ACCTGCTGCTGGACCCGGCCTGGGAGAAGCAGCAGCGCAAGAAGACAGCGACAGCTGTGGCGCACTGCAAACGCGGCAATGGTCTCATCA
AGCTGCTGGAGCCAGTTCTGCTTCTCGGCAAGGAGCGATTTGCTGGTGTAGACATCCGTGTCCGTGTAAAGGGTGGTGGTCACGTGGCCC
AGATTTATGCTATCCGTCAGTCCATCTCCAAAGCCCTGGTGGCCTATTACCAGAAATATGTGGATGAGGCTTCCAAGAAGGAGATCAAAG
ACATCCTCATCCAGTATGACCGGACCCTGCTGGTAGCTGACCCTCGTCGCTGCGAGTCCAAAAAGTTTGGAGGCCCTGGTGCCCGCGCTC
GCTACCAGAAATCCTACCGATAAGCCCATCGTGACTCAAAACTCACTTGTATAATAAACAGTTTTTGAGGGATTTTAAA

>1798_1798_36_ACTN4-RPS16_ACTN4_chr19_39138547_ENST00000424234_RPS16_chr19_39926348_ENST00000601655_length(amino acids)=167AA_BP=54
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKKTATAVAHCKRGNGLIKLLEPVLLLGKERFAGVDIR
VRVKGGGHVAQIYAIRQSISKALVAYYQKYVDEASKKEIKDILIQYDRTLLVADPRRCESKKFGGPGARARYQKSYR

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ACTN4-RPS16


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneACTN4chr19:39138546chr19:39924400ENST00000252699+12112_2654.0912.0VCL
HgeneACTN4chr19:39138546chr19:39924400ENST00000390009+11412_2654.0693.0VCL
HgeneACTN4chr19:39138547chr19:39924401ENST00000252699+12112_2654.0912.0VCL
HgeneACTN4chr19:39138547chr19:39924401ENST00000390009+11412_2654.0693.0VCL
HgeneACTN4chr19:39138547chr19:39926348ENST00000252699+12112_2654.0912.0VCL
HgeneACTN4chr19:39138547chr19:39926348ENST00000390009+11412_2654.0693.0VCL


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneACTN4chr19:39138546chr19:39924400ENST00000252699+121108_12654.0912.0VCL
HgeneACTN4chr19:39138546chr19:39924400ENST00000252699+12140_6154.0912.0VCL
HgeneACTN4chr19:39138546chr19:39924400ENST00000390009+114108_12654.0693.0VCL
HgeneACTN4chr19:39138546chr19:39924400ENST00000390009+11440_6154.0693.0VCL
HgeneACTN4chr19:39138547chr19:39924401ENST00000252699+121108_12654.0912.0VCL
HgeneACTN4chr19:39138547chr19:39924401ENST00000252699+12140_6154.0912.0VCL
HgeneACTN4chr19:39138547chr19:39924401ENST00000390009+114108_12654.0693.0VCL
HgeneACTN4chr19:39138547chr19:39924401ENST00000390009+11440_6154.0693.0VCL
HgeneACTN4chr19:39138547chr19:39926348ENST00000252699+121108_12654.0912.0VCL
HgeneACTN4chr19:39138547chr19:39926348ENST00000252699+12140_6154.0912.0VCL
HgeneACTN4chr19:39138547chr19:39926348ENST00000390009+114108_12654.0693.0VCL
HgeneACTN4chr19:39138547chr19:39926348ENST00000390009+11440_6154.0693.0VCL


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ACTN4-RPS16


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ACTN4-RPS16


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneACTN4C4551527Focal segmental glomerulosclerosis 19GENOMICS_ENGLAND;UNIPROT
HgeneACTN4C0007097Carcinoma1CTD_human
HgeneACTN4C0019193Hepatitis, Toxic1CTD_human
HgeneACTN4C0024667Animal Mammary Neoplasms1CTD_human
HgeneACTN4C0024668Mammary Neoplasms, Experimental1CTD_human
HgeneACTN4C0205696Anaplastic carcinoma1CTD_human
HgeneACTN4C0205697Carcinoma, Spindle-Cell1CTD_human
HgeneACTN4C0205698Undifferentiated carcinoma1CTD_human
HgeneACTN4C0205699Carcinomatosis1CTD_human
HgeneACTN4C0860207Drug-Induced Liver Disease1CTD_human
HgeneACTN4C1257925Mammary Carcinoma, Animal1CTD_human
HgeneACTN4C1262760Hepatitis, Drug-Induced1CTD_human
HgeneACTN4C1868672NEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE1ORPHANET
HgeneACTN4C3658290Drug-Induced Acute Liver Injury1CTD_human
HgeneACTN4C4277682Chemical and Drug Induced Liver Injury1CTD_human
HgeneACTN4C4279912Chemically-Induced Liver Toxicity1CTD_human