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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Fusion gene:BAP1-PBRM1 (FusionGDB2 ID:HG8314TG55193)

Fusion Gene Summary for BAP1-PBRM1

check button Fusion gene summary
Fusion gene informationFusion gene name: BAP1-PBRM1
Fusion gene ID: hg8314tg55193
HgeneTgene
Gene symbol

BAP1

PBRM1

Gene ID

8314

55193

Gene nameBRCA1 associated protein 1polybromo 1
SynonymsHUCEP-13|UCHL2|hucep-6BAF180|PB1
Cytomap('BAP1')('PBRM1')

3p21.1

3p21.1

Type of geneprotein-codingprotein-coding
Descriptionubiquitin carboxyl-terminal hydrolase BAP1BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)cerebral protein 6cerebral protein-13protein polybromo-1BRG1-associated factor 180polybromo-1D
Modification date2020031520200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000296288, ENST00000460680, 
Fusion gene scores* DoF score12 X 13 X 7=109210 X 10 X 7=700
# samples 1310
** MAII scorelog2(13/1092*10)=-3.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(10/700*10)=-2.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: BAP1 [Title/Abstract] AND PBRM1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointBAP1(52438469)-PBRM1(52663051), # samples:2
Anticipated loss of major functional domain due to fusion event.BAP1-PBRM1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
BAP1-PBRM1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
BAP1-PBRM1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
BAP1-PBRM1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneBAP1

GO:0016579

protein deubiquitination

18757409|19815555

HgeneBAP1

GO:0035520

monoubiquitinated protein deubiquitination

24703950

HgeneBAP1

GO:0035522

monoubiquitinated histone H2A deubiquitination

20436459|25451922

HgeneBAP1

GO:0045892

negative regulation of transcription, DNA-templated

25451922


check buttonFusion gene breakpoints across BAP1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across PBRM1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SKCMTCGA-ER-A3ES-06ABAP1chr3

52438469

-PBRM1chr3

52663051

-


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Fusion Gene ORF analysis for BAP1-PBRM1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000296288ENST00000296302BAP1chr3

52438469

-PBRM1chr3

52663051

-
In-frameENST00000296288ENST00000337303BAP1chr3

52438469

-PBRM1chr3

52663051

-
In-frameENST00000296288ENST00000356770BAP1chr3

52438469

-PBRM1chr3

52663051

-
In-frameENST00000296288ENST00000394830BAP1chr3

52438469

-PBRM1chr3

52663051

-
In-frameENST00000296288ENST00000409057BAP1chr3

52438469

-PBRM1chr3

52663051

-
In-frameENST00000296288ENST00000409114BAP1chr3

52438469

-PBRM1chr3

52663051

-
In-frameENST00000296288ENST00000409767BAP1chr3

52438469

-PBRM1chr3

52663051

-
In-frameENST00000296288ENST00000410007BAP1chr3

52438469

-PBRM1chr3

52663051

-
In-frameENST00000460680ENST00000296302BAP1chr3

52438469

-PBRM1chr3

52663051

-
In-frameENST00000460680ENST00000337303BAP1chr3

52438469

-PBRM1chr3

52663051

-
In-frameENST00000460680ENST00000356770BAP1chr3

52438469

-PBRM1chr3

52663051

-
In-frameENST00000460680ENST00000394830BAP1chr3

52438469

-PBRM1chr3

52663051

-
In-frameENST00000460680ENST00000409057BAP1chr3

52438469

-PBRM1chr3

52663051

-
In-frameENST00000460680ENST00000409114BAP1chr3

52438469

-PBRM1chr3

52663051

-
In-frameENST00000460680ENST00000409767BAP1chr3

52438469

-PBRM1chr3

52663051

-
In-frameENST00000460680ENST00000410007BAP1chr3

52438469

-PBRM1chr3

52663051

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000460680BAP1chr352438469-ENST00000356770PBRM1chr352663051-8037172247253251617
ENST00000460680BAP1chr352438469-ENST00000394830PBRM1chr352663051-5392172247251691565
ENST00000460680BAP1chr352438469-ENST00000296302PBRM1chr352663051-5564172247254901672
ENST00000460680BAP1chr352438469-ENST00000337303PBRM1chr352663051-5243172247251691565
ENST00000460680BAP1chr352438469-ENST00000410007PBRM1chr352663051-5323172247252501592
ENST00000460680BAP1chr352438469-ENST00000409057PBRM1chr352663051-5398172247253251617
ENST00000460680BAP1chr352438469-ENST00000409114PBRM1chr352663051-5433172247253791635
ENST00000460680BAP1chr352438469-ENST00000409767PBRM1chr352663051-5267172247252141580
ENST00000296288BAP1chr352438469-ENST00000356770PBRM1chr352663051-754712323648351599
ENST00000296288BAP1chr352438469-ENST00000394830PBRM1chr352663051-490212323646791547
ENST00000296288BAP1chr352438469-ENST00000296302PBRM1chr352663051-507412323650001654
ENST00000296288BAP1chr352438469-ENST00000337303PBRM1chr352663051-475312323646791547
ENST00000296288BAP1chr352438469-ENST00000410007PBRM1chr352663051-483312323647601574
ENST00000296288BAP1chr352438469-ENST00000409057PBRM1chr352663051-490812323648351599
ENST00000296288BAP1chr352438469-ENST00000409114PBRM1chr352663051-494312323648891617
ENST00000296288BAP1chr352438469-ENST00000409767PBRM1chr352663051-477712323647241562

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000460680ENST00000356770BAP1chr352438469-PBRM1chr352663051-0.0001664170.9998336
ENST00000460680ENST00000394830BAP1chr352438469-PBRM1chr352663051-0.0015888070.9984112
ENST00000460680ENST00000296302BAP1chr352438469-PBRM1chr352663051-0.0020139280.9979861
ENST00000460680ENST00000337303BAP1chr352438469-PBRM1chr352663051-0.0016461030.99835396
ENST00000460680ENST00000410007BAP1chr352438469-PBRM1chr352663051-0.0021330530.9978669
ENST00000460680ENST00000409057BAP1chr352438469-PBRM1chr352663051-0.0008794150.99912053
ENST00000460680ENST00000409114BAP1chr352438469-PBRM1chr352663051-0.0027632970.9972367
ENST00000460680ENST00000409767BAP1chr352438469-PBRM1chr352663051-0.0017205360.99827945
ENST00000296288ENST00000356770BAP1chr352438469-PBRM1chr352663051-0.0001022460.9998977
ENST00000296288ENST00000394830BAP1chr352438469-PBRM1chr352663051-0.0009690030.99903107
ENST00000296288ENST00000296302BAP1chr352438469-PBRM1chr352663051-0.0012407880.99875927
ENST00000296288ENST00000337303BAP1chr352438469-PBRM1chr352663051-0.0009553290.9990446
ENST00000296288ENST00000410007BAP1chr352438469-PBRM1chr352663051-0.0012837690.99871624
ENST00000296288ENST00000409057BAP1chr352438469-PBRM1chr352663051-0.0005225610.99947745
ENST00000296288ENST00000409114BAP1chr352438469-PBRM1chr352663051-0.0017053870.99829465
ENST00000296288ENST00000409767BAP1chr352438469-PBRM1chr352663051-0.0010072730.99899274

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Fusion Genomic Features for BAP1-PBRM1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for BAP1-PBRM1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:52438469/chr3:52663051)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgenePBRM1chr3:52438469chr3:52663051ENST0000029630210301468_15994331690.0Compositional biasNote=Pro-rich
TgenePBRM1chr3:52438469chr3:52663051ENST000002963021030630_6334331690.0Compositional biasNote=Poly-Asp
TgenePBRM1chr3:52438469chr3:52663051ENST0000033730310281468_15994331583.0Compositional biasNote=Pro-rich
TgenePBRM1chr3:52438469chr3:52663051ENST000003373031028630_6334331583.0Compositional biasNote=Poly-Asp
TgenePBRM1chr3:52438469chr3:52663051ENST000003567709281468_15994011603.0Compositional biasNote=Pro-rich
TgenePBRM1chr3:52438469chr3:52663051ENST00000356770928630_6334011603.0Compositional biasNote=Poly-Asp
TgenePBRM1chr3:52438469chr3:52663051ENST0000039483011301468_15994331583.0Compositional biasNote=Pro-rich
TgenePBRM1chr3:52438469chr3:52663051ENST000003948301130630_6334331583.0Compositional biasNote=Poly-Asp
TgenePBRM1chr3:52438469chr3:52663051ENST0000040905710291468_15994331635.0Compositional biasNote=Pro-rich
TgenePBRM1chr3:52438469chr3:52663051ENST000004090571029630_6334331635.0Compositional biasNote=Poly-Asp
TgenePBRM1chr3:52438469chr3:52663051ENST0000040911410301468_15994331653.0Compositional biasNote=Pro-rich
TgenePBRM1chr3:52438469chr3:52663051ENST000004091141030630_6334331653.0Compositional biasNote=Poly-Asp
TgenePBRM1chr3:52438469chr3:52663051ENST0000040976710291468_15994331598.0Compositional biasNote=Pro-rich
TgenePBRM1chr3:52438469chr3:52663051ENST000004097671029630_6334331598.0Compositional biasNote=Poly-Asp
TgenePBRM1chr3:52438469chr3:52663051ENST0000041000710291468_15994331610.0Compositional biasNote=Pro-rich
TgenePBRM1chr3:52438469chr3:52663051ENST000004100071029630_6334331610.0Compositional biasNote=Poly-Asp
TgenePBRM1chr3:52438469chr3:52663051ENST0000029630210301379_14474331690.0DNA bindingHMG box
TgenePBRM1chr3:52438469chr3:52663051ENST0000033730310281379_14474331583.0DNA bindingHMG box
TgenePBRM1chr3:52438469chr3:52663051ENST000003567709281379_14474011603.0DNA bindingHMG box
TgenePBRM1chr3:52438469chr3:52663051ENST0000039483011301379_14474331583.0DNA bindingHMG box
TgenePBRM1chr3:52438469chr3:52663051ENST0000040905710291379_14474331635.0DNA bindingHMG box
TgenePBRM1chr3:52438469chr3:52663051ENST0000040911410301379_14474331653.0DNA bindingHMG box
TgenePBRM1chr3:52438469chr3:52663051ENST0000040976710291379_14474331598.0DNA bindingHMG box
TgenePBRM1chr3:52438469chr3:52663051ENST0000041000710291379_14474331610.0DNA bindingHMG box
TgenePBRM1chr3:52438469chr3:52663051ENST0000029630210301156_12724331690.0DomainBAH 2
TgenePBRM1chr3:52438469chr3:52663051ENST000002963021030538_6084331690.0DomainBromo 4
TgenePBRM1chr3:52438469chr3:52663051ENST000002963021030676_7464331690.0DomainBromo 5
TgenePBRM1chr3:52438469chr3:52663051ENST000002963021030792_8624331690.0DomainBromo 6
TgenePBRM1chr3:52438469chr3:52663051ENST000002963021030956_10744331690.0DomainBAH 1
TgenePBRM1chr3:52438469chr3:52663051ENST0000033730310281156_12724331583.0DomainBAH 2
TgenePBRM1chr3:52438469chr3:52663051ENST000003373031028538_6084331583.0DomainBromo 4
TgenePBRM1chr3:52438469chr3:52663051ENST000003373031028676_7464331583.0DomainBromo 5
TgenePBRM1chr3:52438469chr3:52663051ENST000003373031028792_8624331583.0DomainBromo 6
TgenePBRM1chr3:52438469chr3:52663051ENST000003373031028956_10744331583.0DomainBAH 1
TgenePBRM1chr3:52438469chr3:52663051ENST000003567709281156_12724011603.0DomainBAH 2
TgenePBRM1chr3:52438469chr3:52663051ENST00000356770928400_4704011603.0DomainBromo 3
TgenePBRM1chr3:52438469chr3:52663051ENST00000356770928538_6084011603.0DomainBromo 4
TgenePBRM1chr3:52438469chr3:52663051ENST00000356770928676_7464011603.0DomainBromo 5
TgenePBRM1chr3:52438469chr3:52663051ENST00000356770928792_8624011603.0DomainBromo 6
TgenePBRM1chr3:52438469chr3:52663051ENST00000356770928956_10744011603.0DomainBAH 1
TgenePBRM1chr3:52438469chr3:52663051ENST0000039483011301156_12724331583.0DomainBAH 2
TgenePBRM1chr3:52438469chr3:52663051ENST000003948301130538_6084331583.0DomainBromo 4
TgenePBRM1chr3:52438469chr3:52663051ENST000003948301130676_7464331583.0DomainBromo 5
TgenePBRM1chr3:52438469chr3:52663051ENST000003948301130792_8624331583.0DomainBromo 6
TgenePBRM1chr3:52438469chr3:52663051ENST000003948301130956_10744331583.0DomainBAH 1
TgenePBRM1chr3:52438469chr3:52663051ENST0000040905710291156_12724331635.0DomainBAH 2
TgenePBRM1chr3:52438469chr3:52663051ENST000004090571029538_6084331635.0DomainBromo 4
TgenePBRM1chr3:52438469chr3:52663051ENST000004090571029676_7464331635.0DomainBromo 5
TgenePBRM1chr3:52438469chr3:52663051ENST000004090571029792_8624331635.0DomainBromo 6
TgenePBRM1chr3:52438469chr3:52663051ENST000004090571029956_10744331635.0DomainBAH 1
TgenePBRM1chr3:52438469chr3:52663051ENST0000040911410301156_12724331653.0DomainBAH 2
TgenePBRM1chr3:52438469chr3:52663051ENST000004091141030538_6084331653.0DomainBromo 4
TgenePBRM1chr3:52438469chr3:52663051ENST000004091141030676_7464331653.0DomainBromo 5
TgenePBRM1chr3:52438469chr3:52663051ENST000004091141030792_8624331653.0DomainBromo 6
TgenePBRM1chr3:52438469chr3:52663051ENST000004091141030956_10744331653.0DomainBAH 1
TgenePBRM1chr3:52438469chr3:52663051ENST0000040976710291156_12724331598.0DomainBAH 2
TgenePBRM1chr3:52438469chr3:52663051ENST000004097671029538_6084331598.0DomainBromo 4
TgenePBRM1chr3:52438469chr3:52663051ENST000004097671029676_7464331598.0DomainBromo 5
TgenePBRM1chr3:52438469chr3:52663051ENST000004097671029792_8624331598.0DomainBromo 6
TgenePBRM1chr3:52438469chr3:52663051ENST000004097671029956_10744331598.0DomainBAH 1
TgenePBRM1chr3:52438469chr3:52663051ENST0000041000710291156_12724331610.0DomainBAH 2
TgenePBRM1chr3:52438469chr3:52663051ENST000004100071029538_6084331610.0DomainBromo 4
TgenePBRM1chr3:52438469chr3:52663051ENST000004100071029676_7464331610.0DomainBromo 5
TgenePBRM1chr3:52438469chr3:52663051ENST000004100071029792_8624331610.0DomainBromo 6
TgenePBRM1chr3:52438469chr3:52663051ENST000004100071029956_10744331610.0DomainBAH 1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneBAP1chr3:52438469chr3:52663051ENST00000460680-1217630_661416730.0Coiled coilOntology_term=ECO:0000255
TgenePBRM1chr3:52438469chr3:52663051ENST000002963021030200_2704331690.0DomainBromo 2
TgenePBRM1chr3:52438469chr3:52663051ENST000002963021030400_4704331690.0DomainBromo 3
TgenePBRM1chr3:52438469chr3:52663051ENST00000296302103064_1344331690.0DomainBromo 1
TgenePBRM1chr3:52438469chr3:52663051ENST000003373031028200_2704331583.0DomainBromo 2
TgenePBRM1chr3:52438469chr3:52663051ENST000003373031028400_4704331583.0DomainBromo 3
TgenePBRM1chr3:52438469chr3:52663051ENST00000337303102864_1344331583.0DomainBromo 1
TgenePBRM1chr3:52438469chr3:52663051ENST00000356770928200_2704011603.0DomainBromo 2
TgenePBRM1chr3:52438469chr3:52663051ENST0000035677092864_1344011603.0DomainBromo 1
TgenePBRM1chr3:52438469chr3:52663051ENST000003948301130200_2704331583.0DomainBromo 2
TgenePBRM1chr3:52438469chr3:52663051ENST000003948301130400_4704331583.0DomainBromo 3
TgenePBRM1chr3:52438469chr3:52663051ENST00000394830113064_1344331583.0DomainBromo 1
TgenePBRM1chr3:52438469chr3:52663051ENST000004090571029200_2704331635.0DomainBromo 2
TgenePBRM1chr3:52438469chr3:52663051ENST000004090571029400_4704331635.0DomainBromo 3
TgenePBRM1chr3:52438469chr3:52663051ENST00000409057102964_1344331635.0DomainBromo 1
TgenePBRM1chr3:52438469chr3:52663051ENST000004091141030200_2704331653.0DomainBromo 2
TgenePBRM1chr3:52438469chr3:52663051ENST000004091141030400_4704331653.0DomainBromo 3
TgenePBRM1chr3:52438469chr3:52663051ENST00000409114103064_1344331653.0DomainBromo 1
TgenePBRM1chr3:52438469chr3:52663051ENST000004097671029200_2704331598.0DomainBromo 2
TgenePBRM1chr3:52438469chr3:52663051ENST000004097671029400_4704331598.0DomainBromo 3
TgenePBRM1chr3:52438469chr3:52663051ENST00000409767102964_1344331598.0DomainBromo 1
TgenePBRM1chr3:52438469chr3:52663051ENST000004100071029200_2704331610.0DomainBromo 2
TgenePBRM1chr3:52438469chr3:52663051ENST000004100071029400_4704331610.0DomainBromo 3
TgenePBRM1chr3:52438469chr3:52663051ENST00000410007102964_1344331610.0DomainBromo 1


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Fusion Gene Sequence for BAP1-PBRM1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>8972_8972_1_BAP1-PBRM1_BAP1_chr3_52438469_ENST00000296288_PBRM1_chr3_52663051_ENST00000296302_length(transcript)=5074nt_BP=1232nt
CCTGGACATGGCGCTGAGGGGCCGCCCCGCGGGAAGATGAATAAGGGCTGGCTGGAGCTGGAGAGCGACCCAGGCCTCTTCACCCTGCTC
GTGGAAGATTTCGGTGTCAAGGGGGTGCAAGTGGAGGAGATCTACGACCTTCAGAGCAAATGTCAGGGCCCTGTATATGGATTTATCTTC
CTGTTCAAATGGATCGAAGAGCGCCGGTCCCGGCGAAAGGTCTCTACCTTGGTGGATGATACGTCCGTGATTGATGATGATATTGTGAAT
AACATGTTCTTTGCCCACCAGCTGATACCCAACTCTTGTGCAACTCATGCCTTGCTGAGCGTGCTCCTGAACTGCAGCAGCGTGGACCTG
GGACCCACCCTGAGTCGCATGAAGGACTTCACCAAGGGTTTCAGCCCTGAGAGCAAAGGATATGCGATTGGCAATGCCCCGGAGTTGGCC
AAGGCCCATAATAGCCATGCCAGGCCCGAGCCACGCCACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATGGAGGCGTTC
CACTTTGTCAGCTATGTGCCTATCACAGGCCGGCTCTTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCCTGGGGGGAG
GACGAGGAGTGGACAGACAAGGCCCGGCGGGTCATCATGGAGCGTATCGGCCTCGCCACTGCAGGGATCAAGTATGAGGCCAGGCTGCAT
GTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGATAAGAGTAACACAGCCAGAGCTGATTCAGACCCACAAGTCT
CAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCCGCTGGTGCTGGAAGCAAACAGGGCCCCTGCAGCCTCTGAG
GGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGCCCCATCCCACAGCCCTCCCAACAAACCCAAGCTAGTGGTG
AAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCATTGTCCAGCGGCTGCCGGCCTTTCTAGACAATCACAATTAT
GCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCGCAGCCGAGTTCCAGTCCGCCCACCCCAGCAGTACTCAGAT
GATGAGGATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAACTCTGCCCTTAGAACAAAACTGAAGAATCAAGAATATGAA
ACTTTAGATCATTTGGAGTGTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTT
CTAAAATTGCAGCAAGTTATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCC
ACCTCTGATACTGGTAGTGCCAAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCT
CGAGAGCCAGGTTCAGGCAGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTG
GAGCCAATGGACTTGAAAATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATG
TTCCGGAATGCCAGGCACTATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAA
GAGCTGGGCCCACTGCCTGATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAA
TACATGACTCCAATGCAGCAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATA
TTTCTGAGGCTTCCCTCTAGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATG
ATGGCCAACAAGTACCAAGATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCT
TTGATCTACAAAGATGCTCTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAAT
GTGACTTTGCTGATTCAAGAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCT
TTAGCAGAAATTCCTGCTGTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGC
TACCGTCGGCTTGATTTATTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAA
GATGCAGTAGAACTTCAGCAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTAT
ACCACAAAACATTTGCATAATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAA
GAAAAAAGAGAAGCTGAAAAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTT
AAAAACAGCATGTACCATGTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTG
TGGGAGGATTCAGCTGGTGAAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTA
GAAAAAGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATAC
TTTAAGTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATT
AAACTGTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAAT
GCAGATAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGAT
GTCCCTGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGT
GTCTTCATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGC
CCCATCTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACC
TGCCCCATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGAC
ATTCTGCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTG
GTAGATGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAA
GCTAAATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCT
CAGCTTCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAG
AAGGAAGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGAC
TACTCTTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGAGCGGGCAGCT
AAAGTTGCTGAGCAGCAGGAGAGAGAGCGAGCAGCACAGCAACAGCAGCCGAGTGCTTCTCCCCGAGCAGGCACCCCTGTGGGGGCTCTC
ATGGGGGTGGTGCCACCACCAACACCAATGGGGATGCTCAATCAGCAGTTGACACCTGTTGCAGGCATGATGGGTGGCTATCCGCCAGGC
CTTCCACCTTTGCAGGGCCCAGTTGATGGCCTTGTTAGCATGGGCAGCATGCAGCCACTTCACCCTGGGGGGCCTCCACCCCACCATCTT
CCGCCAGGTGTGCCTGGCCTCCCGGGCATCCCACCACCGGGTGTGATGAACCAAGGAGTGGCCCCTATGGTAGGGACTCCAGCACCAGGT
GGAAGTCCATATGGACAACAGGTGGGAGTTTTGGGGCCTCCAGGGCAGCAGGCACCACCTCCATATCCCGGCCCACATCCAGCTGGACCC
CCTGTCATACAGCAGCCAACAACACCCATGTTTGTAGCTCCCCCACCAAAGACCCAGCGGCTTCTTCACTCAGAGGCCTACCTGAAATAC
ATTGAAGGACTCAGTGCGGAGTCCAACAGCATTAGCAAGTGGGATCAGACACTGGCAGCTCGAAGACGCGACGTCCATTTGTCGAAAGAA
CAGGAGAGCCGCCTACCCTCTCACTGGCTGAAAAGCAAAGGGGCCCACACCACCATGGCAGATGCCCTCTGGCGCCTTCGAGATTTGATG
CTCCGGGACACCCTCAACATTCGCCAAGCATACAACCTAGAAAATGTTTAATCACATCATTACGTTTCTTTTATATAGAAGCATAAAGAG

>8972_8972_1_BAP1-PBRM1_BAP1_chr3_52438469_ENST00000296288_PBRM1_chr3_52663051_ENST00000296302_length(amino acids)=1654AA_BP=398
MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVYGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNS
CATHALLSVLLNCSSVDLGPTLSRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRL
FELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGIKYEARLHVLKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKSA
SNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAFLDNHNYAKSPMQEEEDLA
AGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKK
ELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNI
RNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEV
YEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKV
LLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMF
EVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSS
GAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNK
VPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDN
SEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHE
PTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPI
VPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSG
YILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEERAAKVAEQQERERAAQQQQPSASPRAGTPVGALMGVVPPPTPMGM
LNQQLTPVAGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLG
PPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKS

--------------------------------------------------------------
>8972_8972_2_BAP1-PBRM1_BAP1_chr3_52438469_ENST00000296288_PBRM1_chr3_52663051_ENST00000337303_length(transcript)=4753nt_BP=1232nt
CCTGGACATGGCGCTGAGGGGCCGCCCCGCGGGAAGATGAATAAGGGCTGGCTGGAGCTGGAGAGCGACCCAGGCCTCTTCACCCTGCTC
GTGGAAGATTTCGGTGTCAAGGGGGTGCAAGTGGAGGAGATCTACGACCTTCAGAGCAAATGTCAGGGCCCTGTATATGGATTTATCTTC
CTGTTCAAATGGATCGAAGAGCGCCGGTCCCGGCGAAAGGTCTCTACCTTGGTGGATGATACGTCCGTGATTGATGATGATATTGTGAAT
AACATGTTCTTTGCCCACCAGCTGATACCCAACTCTTGTGCAACTCATGCCTTGCTGAGCGTGCTCCTGAACTGCAGCAGCGTGGACCTG
GGACCCACCCTGAGTCGCATGAAGGACTTCACCAAGGGTTTCAGCCCTGAGAGCAAAGGATATGCGATTGGCAATGCCCCGGAGTTGGCC
AAGGCCCATAATAGCCATGCCAGGCCCGAGCCACGCCACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATGGAGGCGTTC
CACTTTGTCAGCTATGTGCCTATCACAGGCCGGCTCTTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCCTGGGGGGAG
GACGAGGAGTGGACAGACAAGGCCCGGCGGGTCATCATGGAGCGTATCGGCCTCGCCACTGCAGGGATCAAGTATGAGGCCAGGCTGCAT
GTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGATAAGAGTAACACAGCCAGAGCTGATTCAGACCCACAAGTCT
CAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCCGCTGGTGCTGGAAGCAAACAGGGCCCCTGCAGCCTCTGAG
GGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGCCCCATCCCACAGCCCTCCCAACAAACCCAAGCTAGTGGTG
AAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCATTGTCCAGCGGCTGCCGGCCTTTCTAGACAATCACAATTAT
GCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCGCAGCCGAGTTCCAGTCCGCCCACCCCAGCAGTACTCAGAT
GATGAGGATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAACTCTGCCCTTAGAACAAAACTGAAGAATCAAGAATATGAA
ACTTTAGATCATTTGGAGTGTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTT
CTAAAATTGCAGCAAGTTATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCC
ACCTCTGATACTGGTAGTGCCAAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCT
CGAGAGCCAGGTTCAGGCAGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTG
GAGCCAATGGACTTGAAAATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATG
TTCCGGAATGCCAGGCACTATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAA
GAGCTGGGCCCACTGCCTGATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAA
TACATGACTCCAATGCAGCAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATA
TTTCTGAGGCTTCCCTCTAGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATG
ATGGCCAACAAGTACCAAGATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCT
TTGATCTACAAAGATGCTCTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAAT
GTGACTTTGCTGATTCAAGAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCT
TTAGCAGAAATTCCTGCTGTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGC
TACCGTCGGCTTGATTTATTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAA
GATGCAGTAGAACTTCAGCAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTAT
ACCACAAAACATTTGCATAATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAA
GAAAAAAGAGAAGCTGAAAAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTT
AAAAACAGCATGTACCATGTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTG
TGGGAGGATTCAGCTGGTGAAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTA
GAAAAAGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATAC
TTTAAGTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATT
AAACTGTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAAT
GCAGATAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGAT
GTCCCTGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGT
GTCTTCATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGC
CCCATCTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACC
TGCCCCATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGAC
ATTCTGCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTG
GTAGATGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAA
GCTAAATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCT
CAGCTTCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAG
AAGGAAGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGAC
TACTCTTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGGTGTGATGAAC
CAAGGAGTGGCCCCTATGGTAGGGACTCCAGCACCAGGTGGAAGTCCATATGGACAACAGGTGGGAGTTTTGGGGCCTCCAGGGCAGCAG
GCACCACCTCCATATCCCGGCCCACATCCAGCTGGACCCCCTGTCATACAGCAGCCAACAACACCCATGTTTGTAGCTCCCCCACCAAAG
ACCCAGCGGCTTCTTCACTCAGAGGCCTACCTGAAATACATTGAAGGACTCAGTGCGGAGTCCAACAGCATTAGCAAGTGGGATCAGACA
CTGGCAGCTCGAAGACGCGACGTCCATTTGTCGAAAGAACAGGAGAGCCGCCTACCCTCTCACTGGCTGAAAAGCAAAGGGGCCCACACC
ACCATGGCAGATGCCCTCTGGCGCCTTCGAGATTTGATGCTCCGGGACACCCTCAACATTCGCCAAGCATACAACCTAGAAAATGTTTAA

>8972_8972_2_BAP1-PBRM1_BAP1_chr3_52438469_ENST00000296288_PBRM1_chr3_52663051_ENST00000337303_length(amino acids)=1547AA_BP=398
MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVYGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNS
CATHALLSVLLNCSSVDLGPTLSRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRL
FELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGIKYEARLHVLKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKSA
SNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAFLDNHNYAKSPMQEEEDLA
AGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKK
ELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNI
RNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEV
YEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKV
LLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMF
EVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSS
GAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNK
VPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDN
SEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHE
PTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPI
VPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSG
YILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAG
PPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDL

--------------------------------------------------------------
>8972_8972_3_BAP1-PBRM1_BAP1_chr3_52438469_ENST00000296288_PBRM1_chr3_52663051_ENST00000356770_length(transcript)=7547nt_BP=1232nt
CCTGGACATGGCGCTGAGGGGCCGCCCCGCGGGAAGATGAATAAGGGCTGGCTGGAGCTGGAGAGCGACCCAGGCCTCTTCACCCTGCTC
GTGGAAGATTTCGGTGTCAAGGGGGTGCAAGTGGAGGAGATCTACGACCTTCAGAGCAAATGTCAGGGCCCTGTATATGGATTTATCTTC
CTGTTCAAATGGATCGAAGAGCGCCGGTCCCGGCGAAAGGTCTCTACCTTGGTGGATGATACGTCCGTGATTGATGATGATATTGTGAAT
AACATGTTCTTTGCCCACCAGCTGATACCCAACTCTTGTGCAACTCATGCCTTGCTGAGCGTGCTCCTGAACTGCAGCAGCGTGGACCTG
GGACCCACCCTGAGTCGCATGAAGGACTTCACCAAGGGTTTCAGCCCTGAGAGCAAAGGATATGCGATTGGCAATGCCCCGGAGTTGGCC
AAGGCCCATAATAGCCATGCCAGGCCCGAGCCACGCCACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATGGAGGCGTTC
CACTTTGTCAGCTATGTGCCTATCACAGGCCGGCTCTTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCCTGGGGGGAG
GACGAGGAGTGGACAGACAAGGCCCGGCGGGTCATCATGGAGCGTATCGGCCTCGCCACTGCAGGGATCAAGTATGAGGCCAGGCTGCAT
GTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGATAAGAGTAACACAGCCAGAGCTGATTCAGACCCACAAGTCT
CAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCCGCTGGTGCTGGAAGCAAACAGGGCCCCTGCAGCCTCTGAG
GGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGCCCCATCCCACAGCCCTCCCAACAAACCCAAGCTAGTGGTG
AAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCATTGTCCAGCGGCTGCCGGCCTTTCTAGACAATCACAATTAT
GCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCGCAGCCGAGTTCCAGTCCGCCCACCCCAGCAGTACTCAGAT
GATGAGGATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAACTCTGCCCTTAGAACAAAACTGAAGAATCAAGAATATGAA
ACTTTAGATCATTTGGAGTGTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTT
CTAAAATTGCAGCAAGTTATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCC
ACCTCTGATACTGGTAGTGCCAAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCT
CGAGAGCCAGGTTCAGGCAGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTG
GAGCCAATGGACTTGAAAATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATG
TTCCGGAATGCCAGGCACTATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAA
GAGCTGGGCCCACTGCCTGATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAA
TACATGACTCCAATGCAGCAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATA
TTTCTGAGGCTTCCCTCTAGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATG
ATGGCCAACAAGTACCAAGATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCT
TTGATCTACAAAGATGCTCTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAAT
GTGACTTTGCTGATTCAAGAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCT
TTAGCAGAAATTCCTGCTGTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGC
TACCGTCGGCTTGATTTATTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAA
GATGCAGTAGAACTTCAGCAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTAT
ACCACAAAACATTTGCATAATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAA
GAAAAAAGAGAAGCTGAAAAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTT
AAAAACAGCATGTACCATGTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTG
TGGGAGGATTCAGCTGGTGAAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTA
GAAAAAGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATAC
TTTAAGTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATT
AAACTGTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAAT
GCAGATAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGAT
GTCCCTGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGT
GTCTTCATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGC
CCCATCTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACC
TGCCCCATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGAC
ATTCTGCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTG
GTAGATGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAA
GCTAAATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCT
CAGCTTCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAG
AAGGAAGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGAC
TACTCTTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGGCATGATGGGT
GGCTATCCGCCAGGCCTTCCACCTTTGCAGGGCCCAGTTGATGGCCTTGTTAGCATGGGCAGCATGCAGCCACTTCACCCTGGGGGGCCT
CCACCCCACCATCTTCCGCCAGGTGTGCCTGGCCTCCCGGGCATCCCACCACCGGGTGTGATGAACCAAGGAGTGGCCCCTATGGTAGGG
ACTCCAGCACCAGGTGGAAGTCCATATGGACAACAGGTGGGAGTTTTGGGGCCTCCAGGGCAGCAGGCACCACCTCCATATCCCGGCCCA
CATCCAGCTGGACCCCCTGTCATACAGCAGCCAACAACACCCATGTTTGTAGCTCCCCCACCAAAGACCCAGCGGCTTCTTCACTCAGAG
GCCTACCTGAAATACATTGAAGGACTCAGTGCGGAGTCCAACAGCATTAGCAAGTGGGATCAGACACTGGCAGCTCGAAGACGCGACGTC
CATTTGTCGAAAGAACAGGAGAGCCGCCTACCCTCTCACTGGCTGAAAAGCAAAGGGGCCCACACCACCATGGCAGATGCCCTCTGGCGC
CTTCGAGATTTGATGCTCCGGGACACCCTCAACATTCGCCAAGCATACAACCTAGAAAATGTTTAATCACATCATTACGTTTCTTTTATA
TAGAAGCATAAAGAGTTGTGGATCAGTAGCCATTTTAGTTACTGGGGGTGGGGGGAAGGAACAAAGGAGGATAATTTTTATTGCATTTTA
CTGTACATCACAAGGCCATTTTTATATACGGACACTTTTAATAAGCTATTTCAATTTGTTTGTTATATTAAGTTGACTTTATCAAATACA
CAAAGATTTTTTTGCATATGTTTCCTTCGTTTAAAACCAGTTTCATAATTGGTTGTATATGTAGACTTGGAGTTTTATCTTTTTACTTGT
TGCCATGGAACTGAAACCATTAGAGGTTTTTGTCTTGGCTTGGGGTTTTTGTTTTCTTGGTTTTGGGTTTTTTTATATATATATATAAAA
GAACAAAATGAAAAAAAACACACACACACAAGAGTTTACAGATTAGTTTAAATTGATAATGAAATGTGAAGTTTGTCCTAGTTTACATCT
TAGAGAGGGGAGTATACTTGTGTTTGTTTCATGTGCCTGAATATCTTAAGCCACTTTCTGCAAAAGCTGTTTCTTACAGATGAAGTGCTT
TCTTTGAAAGGTGGTTATTTAGGTTTTAGATGTTTAATAGACACAGCACATTTGCTCTATTAACTCAGAGGCTCACTACAGAAATATGTA
ATCAGTGCTGTGCATCTGTCTGCAGCTAATGTACCTCCTGGACACCAGGAGGGGAAAAAGCACTTTTTCAATTGTGCTGAGTTAGACATC
TGTGAGTTAGACTATGGTGTCAGTGATTTTTGCAGAACACGTGCACAACCCTGAGGTATGTTTAATCTAGGCAGGTACGTTTAAGGATAT
TTTGATCTATTTATAATGAATTCACAATTTATGCCTATAAATTTCAGATGATTTAAAATTTTAAACCTGTTACATTGAAAAACATTGAAG
TTCGTCTTGAAGAAAGCATTAAGGTATGCATGGAGGTGATTTATTTTTAAACATAACACCTAACCTAACATGGGTAAGAGAGTATGGAAC
TAGATATGAGCTGTATAAGAAGCATAATTGTGAACAAGTAGATTGATTGCCTTCATATACAAGTATGTTTTAGTATTCCTTATTTCCTTA
TTATCAGATGTATTTTTTCTTTTAAGTTTCAATGTTGTTATAATTCTCAACCAGAAATTTAATACTTTCTAAAATATTTTTTAAATTTAG
CTTGTGCTTTTGAATTACAGGAGAAGGGAATCATAATTTAATAAAACGCTTACTAGAAAGACCATTACAGATCCCAAACACTTGGGTTTG
GTGACCCTGTCTTTCTTATATGACCCTACAATAAACATTTGAAGGCAGCATAGGATGGCAGACAGTAGGAACATTGTTTCACTTGGCGGC
ATGTTTTTGAAACCTGCTTTATAGTAACTGGGTGATTGCCATTGTGGTAGAGCTTCCACTGCTGTTTATAATCTGAGAGAGTTAATCTCA
GAGGATGCTTTTTTCCTTTTAATCTGCTATGAATCAGTACCCAGATGTTTAATTACTGTACTTATTAAATCATGAGGGCAAAAGAGTGTA
GAATGGAAAAAAGTCTCTTGTATCTAGATACTTTAAATATGGGAGGCCCTTTAACTTAATTGCCTTTAGTCAACCACTGGATTTGAATTT
GCATCAAGTATTTTAAATAATATTGAATTTAAAAAAATGTATTGCAGTAGTGTGTCAGTACCTTATTGTTAAAGTGAGTCAGATAAATCT
TCAATTCCTGGCTATTTGGGCAATTGAATCATCATGGACTGTATAATGCAATCAGATTATTTTGTTTCTAGACATCCTTGAATTACACCA
AAGAACATGAAATTTAGTTGTGGTTAAATTATTTATTTATTTCATGCATTCATTTTATTTCCCTTAAGGTCTGGATGAGACTTCTTTGGG
GAGCCTCTAAAAAAATTTTTCACTGGGGGCCACGTGGGTCATTAGAAGCCAGAGCTCTCCTCCAGGCTCCTTCCCAGTGCCTAGAGGTGC
TATAGGAAACATAGATCCAGCCAGGGGCTTCCCTAAAGCAGTGCAGCACCGGCCCAGGGCATCACTAGACAGGCCCTAATTAAGTTTTTT
TTAAAAAGCCTGTGTATTTATTTTAGAATCATGTTTTTCTGTATATTAACTTGGGGGATATCGTTAATATTTAGGATATAAGATTTGAGG
TCAGCCATCTTCAAAAAAGAAAAAAAAATTGACTCAAGAAAGTACAAGTAAACTATACACCTTTTTTTCATAAGTTTTAGGAACTGTAGT
AATGTGGCTTAGAAAGTATAATGGCCTAAATGTTTTCAAAATGTAAGTTCCTGTGGAGAAGAATTGTTTATATTGCAAACGGGGGGACTG
AGGGGAACCTGTAGGTTTAAAACAGTATGTTTGTCAGCCAACTGATTTAAAAGGCCTTTAACTGTTTTGGTTGTTGTTTTTTTTTTAAGC
CACTCTCCCCTTCCTATGAGGAAGAATTGAGAGGGGCACCTATTTCTGTAAAATCCCCAAATTGGTGTTGATGATTTTGAGCTTGAATGT
TTTCATACCTGATTAAAACTTGGTTTATTCTAATTTCTGTATCATATCATCTGAGGTTTACGTGGTAACTAGTCTTATAACATGTATGTA

>8972_8972_3_BAP1-PBRM1_BAP1_chr3_52438469_ENST00000296288_PBRM1_chr3_52663051_ENST00000356770_length(amino acids)=1599AA_BP=398
MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVYGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNS
CATHALLSVLLNCSSVDLGPTLSRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRL
FELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGIKYEARLHVLKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKSA
SNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAFLDNHNYAKSPMQEEEDLA
AGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKK
ELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNI
RNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEV
YEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKV
LLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMF
EVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSS
GAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNK
VPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDN
SEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHE
PTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPI
VPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSG
YILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGL
PGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAE

--------------------------------------------------------------
>8972_8972_4_BAP1-PBRM1_BAP1_chr3_52438469_ENST00000296288_PBRM1_chr3_52663051_ENST00000394830_length(transcript)=4902nt_BP=1232nt
CCTGGACATGGCGCTGAGGGGCCGCCCCGCGGGAAGATGAATAAGGGCTGGCTGGAGCTGGAGAGCGACCCAGGCCTCTTCACCCTGCTC
GTGGAAGATTTCGGTGTCAAGGGGGTGCAAGTGGAGGAGATCTACGACCTTCAGAGCAAATGTCAGGGCCCTGTATATGGATTTATCTTC
CTGTTCAAATGGATCGAAGAGCGCCGGTCCCGGCGAAAGGTCTCTACCTTGGTGGATGATACGTCCGTGATTGATGATGATATTGTGAAT
AACATGTTCTTTGCCCACCAGCTGATACCCAACTCTTGTGCAACTCATGCCTTGCTGAGCGTGCTCCTGAACTGCAGCAGCGTGGACCTG
GGACCCACCCTGAGTCGCATGAAGGACTTCACCAAGGGTTTCAGCCCTGAGAGCAAAGGATATGCGATTGGCAATGCCCCGGAGTTGGCC
AAGGCCCATAATAGCCATGCCAGGCCCGAGCCACGCCACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATGGAGGCGTTC
CACTTTGTCAGCTATGTGCCTATCACAGGCCGGCTCTTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCCTGGGGGGAG
GACGAGGAGTGGACAGACAAGGCCCGGCGGGTCATCATGGAGCGTATCGGCCTCGCCACTGCAGGGATCAAGTATGAGGCCAGGCTGCAT
GTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGATAAGAGTAACACAGCCAGAGCTGATTCAGACCCACAAGTCT
CAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCCGCTGGTGCTGGAAGCAAACAGGGCCCCTGCAGCCTCTGAG
GGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGCCCCATCCCACAGCCCTCCCAACAAACCCAAGCTAGTGGTG
AAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCATTGTCCAGCGGCTGCCGGCCTTTCTAGACAATCACAATTAT
GCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCGCAGCCGAGTTCCAGTCCGCCCACCCCAGCAGTACTCAGAT
GATGAGGATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAACTCTGCCCTTAGAACAAAACTGAAGAATCAAGAATATGAA
ACTTTAGATCATTTGGAGTGTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTT
CTAAAATTGCAGCAAGTTATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCC
ACCTCTGATACTGGTAGTGCCAAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCT
CGAGAGCCAGGTTCAGGCAGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTG
GAGCCAATGGACTTGAAAATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATG
TTCCGGAATGCCAGGCACTATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAA
GAGCTGGGCCCACTGCCTGATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAA
TACATGACTCCAATGCAGCAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATA
TTTCTGAGGCTTCCCTCTAGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATG
ATGGCCAACAAGTACCAAGATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCT
TTGATCTACAAAGATGCTCTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAAT
GTGACTTTGCTGATTCAAGAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCT
TTAGCAGAAATTCCTGCTGTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGC
TACCGTCGGCTTGATTTATTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAA
GATGCAGTAGAACTTCAGCAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTAT
ACCACAAAACATTTGCATAATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAA
GAAAAAAGAGAAGCTGAAAAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTT
AAAAACAGCATGTACCATGTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTG
TGGGAGGATTCAGCTGAAAAAGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATG
TTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAA
TCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCC
TCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAA
AAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTG
AAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCT
GCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGT
AATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAA
ATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCA
CTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAG
ATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGTCTACCCCA
AAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCT
GTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAA
GCAGAATATGAAGGCATGATGGGTGGCTATCCGCCAGGCCTTCCACCTTTGCAGGGCCCAGTTGATGGCCTTGTTAGCATGGGCAGCATG
CAGCCACTTCACCCTGGGGGGCCTCCACCCCACCATCTTCCGCCAGGTGTGCCTGGCCTCCCGGGCATCCCACCACCGGGTGTGATGAAC
CAAGGAGTGGCCCCTATGGTAGGGACTCCAGCACCAGGTGGAAGTCCATATGGACAACAGGTGGGAGTTTTGGGGCCTCCAGGGCAGCAG
GCACCACCTCCATATCCCGGCCCACATCCAGCTGGACCCCCTGTCATACAGCAGCCAACAACACCCATGTTTGTAGCTCCCCCACCAAAG
ACCCAGCGGCTTCTTCACTCAGAGGCCTACCTGAAATACATTGAAGGACTCAGTGCGGAGTCCAACAGCATTAGCAAGTGGGATCAGACA
CTGGCAGCTCGAAGACGCGACGTCCATTTGTCGAAAGAACAGGAGAGCCGCCTACCCTCTCACTGGCTGAAAAGCAAAGGGGCCCACACC
ACCATGGCAGATGCCCTCTGGCGCCTTCGAGATTTGATGCTCCGGGACACCCTCAACATTCGCCAAGCATACAACCTAGAAAATGTTTAA
TCACATCATTACGTTTCTTTTATATAGAAGCATAAAGAGTTGTGGATCAGTAGCCATTTTAGTTACTGGGGGTGGGGGGAAGGAACAAAG
GAGGATAATTTTTATTGCATTTTACTGTACATCACAAGGCCATTTTTATATACGGACACTTTTAATAAGCTATTTCAATTTGTTTGTTAT

>8972_8972_4_BAP1-PBRM1_BAP1_chr3_52438469_ENST00000296288_PBRM1_chr3_52663051_ENST00000394830_length(amino acids)=1547AA_BP=398
MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVYGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNS
CATHALLSVLLNCSSVDLGPTLSRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRL
FELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGIKYEARLHVLKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKSA
SNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAFLDNHNYAKSPMQEEEDLA
AGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKK
ELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNI
RNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEV
YEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKV
LLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMF
EVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSS
GAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPEN
FRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN
GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCIL
GKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE
GGDDDIEEMGEEDSESTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGMMGGYPP
GLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAG
PPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDL

--------------------------------------------------------------
>8972_8972_5_BAP1-PBRM1_BAP1_chr3_52438469_ENST00000296288_PBRM1_chr3_52663051_ENST00000409057_length(transcript)=4908nt_BP=1232nt
CCTGGACATGGCGCTGAGGGGCCGCCCCGCGGGAAGATGAATAAGGGCTGGCTGGAGCTGGAGAGCGACCCAGGCCTCTTCACCCTGCTC
GTGGAAGATTTCGGTGTCAAGGGGGTGCAAGTGGAGGAGATCTACGACCTTCAGAGCAAATGTCAGGGCCCTGTATATGGATTTATCTTC
CTGTTCAAATGGATCGAAGAGCGCCGGTCCCGGCGAAAGGTCTCTACCTTGGTGGATGATACGTCCGTGATTGATGATGATATTGTGAAT
AACATGTTCTTTGCCCACCAGCTGATACCCAACTCTTGTGCAACTCATGCCTTGCTGAGCGTGCTCCTGAACTGCAGCAGCGTGGACCTG
GGACCCACCCTGAGTCGCATGAAGGACTTCACCAAGGGTTTCAGCCCTGAGAGCAAAGGATATGCGATTGGCAATGCCCCGGAGTTGGCC
AAGGCCCATAATAGCCATGCCAGGCCCGAGCCACGCCACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATGGAGGCGTTC
CACTTTGTCAGCTATGTGCCTATCACAGGCCGGCTCTTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCCTGGGGGGAG
GACGAGGAGTGGACAGACAAGGCCCGGCGGGTCATCATGGAGCGTATCGGCCTCGCCACTGCAGGGATCAAGTATGAGGCCAGGCTGCAT
GTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGATAAGAGTAACACAGCCAGAGCTGATTCAGACCCACAAGTCT
CAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCCGCTGGTGCTGGAAGCAAACAGGGCCCCTGCAGCCTCTGAG
GGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGCCCCATCCCACAGCCCTCCCAACAAACCCAAGCTAGTGGTG
AAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCATTGTCCAGCGGCTGCCGGCCTTTCTAGACAATCACAATTAT
GCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCGCAGCCGAGTTCCAGTCCGCCCACCCCAGCAGTACTCAGAT
GATGAGGATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAACTCTGCCCTTAGAACAAAACTGAAGAATCAAGAATATGAA
ACTTTAGATCATTTGGAGTGTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTT
CTAAAATTGCAGCAAGTTATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCC
ACCTCTGATACTGGTAGTGCCAAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCT
CGAGAGCCAGGTTCAGGCAGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTG
GAGCCAATGGACTTGAAAATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATG
TTCCGGAATGCCAGGCACTATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAA
GAGCTGGGCCCACTGCCTGATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAA
TACATGACTCCAATGCAGCAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATA
TTTCTGAGGCTTCCCTCTAGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATG
ATGGCCAACAAGTACCAAGATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCT
TTGATCTACAAAGATGCTCTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAAT
GTGACTTTGCTGATTCAAGAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCT
TTAGCAGAAATTCCTGCTGTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGC
TACCGTCGGCTTGATTTATTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAA
GATGCAGTAGAACTTCAGCAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTAT
ACCACAAAACATTTGCATAATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAA
GAAAAAAGAGAAGCTGAAAAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTT
AAAAACAGCATGTACCATGTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTG
TGGGAGGATTCAGCTGGTGAAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTA
GAAAAAGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATAC
TTTAAGTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATT
AAACTGTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAAT
GCAGATAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGAT
GTCCCTGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGT
GTCTTCATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGC
CCCATCTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACC
TGCCCCATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGAC
ATTCTGCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTG
GTAGATGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAA
GCTAAATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCT
CAGCTTCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAG
AAGGAAGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGAC
TACTCTTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGGCATGATGGGT
GGCTATCCGCCAGGCCTTCCACCTTTGCAGGGCCCAGTTGATGGCCTTGTTAGCATGGGCAGCATGCAGCCACTTCACCCTGGGGGGCCT
CCACCCCACCATCTTCCGCCAGGTGTGCCTGGCCTCCCGGGCATCCCACCACCGGGTGTGATGAACCAAGGAGTGGCCCCTATGGTAGGG
ACTCCAGCACCAGGTGGAAGTCCATATGGACAACAGGTGGGAGTTTTGGGGCCTCCAGGGCAGCAGGCACCACCTCCATATCCCGGCCCA
CATCCAGCTGGACCCCCTGTCATACAGCAGCCAACAACACCCATGTTTGTAGCTCCCCCACCAAAGACCCAGCGGCTTCTTCACTCAGAG
GCCTACCTGAAATACATTGAAGGACTCAGTGCGGAGTCCAACAGCATTAGCAAGTGGGATCAGACACTGGCAGCTCGAAGACGCGACGTC
CATTTGTCGAAAGAACAGGAGAGCCGCCTACCCTCTCACTGGCTGAAAAGCAAAGGGGCCCACACCACCATGGCAGATGCCCTCTGGCGC
CTTCGAGATTTGATGCTCCGGGACACCCTCAACATTCGCCAAGCATACAACCTAGAAAATGTTTAATCACATCATTACGTTTCTTTTATA

>8972_8972_5_BAP1-PBRM1_BAP1_chr3_52438469_ENST00000296288_PBRM1_chr3_52663051_ENST00000409057_length(amino acids)=1599AA_BP=398
MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVYGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNS
CATHALLSVLLNCSSVDLGPTLSRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRL
FELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGIKYEARLHVLKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKSA
SNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAFLDNHNYAKSPMQEEEDLA
AGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKK
ELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNI
RNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEV
YEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKV
LLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMF
EVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSS
GAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATRKFLEKEVFKSDYYNK
VPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDN
SEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHE
PTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPI
VPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSG
YILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGL
PGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAE

--------------------------------------------------------------
>8972_8972_6_BAP1-PBRM1_BAP1_chr3_52438469_ENST00000296288_PBRM1_chr3_52663051_ENST00000409114_length(transcript)=4943nt_BP=1232nt
CCTGGACATGGCGCTGAGGGGCCGCCCCGCGGGAAGATGAATAAGGGCTGGCTGGAGCTGGAGAGCGACCCAGGCCTCTTCACCCTGCTC
GTGGAAGATTTCGGTGTCAAGGGGGTGCAAGTGGAGGAGATCTACGACCTTCAGAGCAAATGTCAGGGCCCTGTATATGGATTTATCTTC
CTGTTCAAATGGATCGAAGAGCGCCGGTCCCGGCGAAAGGTCTCTACCTTGGTGGATGATACGTCCGTGATTGATGATGATATTGTGAAT
AACATGTTCTTTGCCCACCAGCTGATACCCAACTCTTGTGCAACTCATGCCTTGCTGAGCGTGCTCCTGAACTGCAGCAGCGTGGACCTG
GGACCCACCCTGAGTCGCATGAAGGACTTCACCAAGGGTTTCAGCCCTGAGAGCAAAGGATATGCGATTGGCAATGCCCCGGAGTTGGCC
AAGGCCCATAATAGCCATGCCAGGCCCGAGCCACGCCACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATGGAGGCGTTC
CACTTTGTCAGCTATGTGCCTATCACAGGCCGGCTCTTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCCTGGGGGGAG
GACGAGGAGTGGACAGACAAGGCCCGGCGGGTCATCATGGAGCGTATCGGCCTCGCCACTGCAGGGATCAAGTATGAGGCCAGGCTGCAT
GTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGATAAGAGTAACACAGCCAGAGCTGATTCAGACCCACAAGTCT
CAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCCGCTGGTGCTGGAAGCAAACAGGGCCCCTGCAGCCTCTGAG
GGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGCCCCATCCCACAGCCCTCCCAACAAACCCAAGCTAGTGGTG
AAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCATTGTCCAGCGGCTGCCGGCCTTTCTAGACAATCACAATTAT
GCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCGCAGCCGAGTTCCAGTCCGCCCACCCCAGCAGTACTCAGAT
GATGAGGATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAACTCTGCCCTTAGAACAAAACTGAAGAATCAAGAATATGAA
ACTTTAGATCATTTGGAGTGTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTT
CTAAAATTGCAGCAAGTTATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCC
ACCTCTGATACTGGTAGTGCCAAAAGAAAAAGGAACACTCATGACAGTGAGATGTTGGGTCTCAGGAGGCTATCCAGTAAAAAGAACATA
AGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGAAGACTTTGTGACCTATTTATGGTT
AAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATAATTGAGCATAACATCCGCAATGAC
AAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTATAATGAGGAGGGCTCCCAGGTTTAT
AATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGATGATGATGACATGGCTTCTCCCAAA
CTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAGAAACTAAATGAGGTCTATGAAGCT
GTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGATCTGAGTTGCCTGACTACTATCTG
ACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGATATTGACTCTATGGTTGAGGACTTT
GTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTTGTTCTACACAAAGTCCTGCTTGAA
ACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAGCTTATCCACAATCTTTTTGTGTCA
GTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTGGATCCCAACTTTCCTAACAAACCA
CCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTTCAAGAGCATATGTTTGAAGTATTG
GAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAGTTTTTTATTAAAATTCGTGATGAA
CTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAATGATGTGGAGAAAGAGAGAAAGGAA
AAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAGAGTGAAGATTCCTCTGGTGCTGCA
GGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTTGGAGATTACGTCTATGTGGAACCT
GCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAAAAATGGTTGTATGGCTGTTGGTTT
TACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTT
AGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTC
TGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGG
GATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGAC
AGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTT
GAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGA
ATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAA
ATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTC
AAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATG
AAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAG
AAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAG
ATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTAC
ACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTG
TTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGA
AATCTTGAGACAGCCAAGAAAGCAGAATATGAAGAGCGGGCAGCTAAAGTTGCTGAGCAGCAGGAGAGAGAGCGAGCAGCACAGCAACAG
CAGCCGAGTGCTTCTCCCCGAGCAGGCACCCCTGTGGGGGCTCTCATGGGGGTGGTGCCACCACCAACACCAATGGGGATGCTCAATCAG
CAGTTGACACCTGTTGCAGGTGTGATGAACCAAGGAGTGGCCCCTATGGTAGGGACTCCAGCACCAGGTGGAAGTCCATATGGACAACAG
GTGGGAGTTTTGGGGCCTCCAGGGCAGCAGGCACCACCTCCATATCCCGGCCCACATCCAGCTGGACCCCCTGTCATACAGCAGCCAACA
ACACCCATGTTTGTAGCTCCCCCACCAAAGACCCAGCGGCTTCTTCACTCAGAGGCCTACCTGAAATACATTGAAGGACTCAGTGCGGAG
TCCAACAGCATTAGCAAGTGGGATCAGACACTGGCAGCTCGAAGACGCGACGTCCATTTGTCGAAAGAACAGGAGAGCCGCCTACCCTCT
CACTGGCTGAAAAGCAAAGGGGCCCACACCACCATGGCAGATGCCCTCTGGCGCCTTCGAGATTTGATGCTCCGGGACACCCTCAACATT

>8972_8972_6_BAP1-PBRM1_BAP1_chr3_52438469_ENST00000296288_PBRM1_chr3_52663051_ENST00000409114_length(amino acids)=1617AA_BP=398
MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVYGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNS
CATHALLSVLLNCSSVDLGPTLSRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRL
FELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGIKYEARLHVLKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKSA
SNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAFLDNHNYAKSPMQEEEDLA
AGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKK
ELARRDDIEDGDSMISSATSDTGSAKRKRNTHDSEMLGLRRLSSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYK
IILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPK
KSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNE
PESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVE
NNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLK
REEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATR
KFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASV
FANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAY
FYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLS
AKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKG
SAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEERAAKVAEQQERERAAQQQQPSASPRAGTPV
GALMGVVPPPTPMGMLNQQLTPVAGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQ

--------------------------------------------------------------
>8972_8972_7_BAP1-PBRM1_BAP1_chr3_52438469_ENST00000296288_PBRM1_chr3_52663051_ENST00000409767_length(transcript)=4777nt_BP=1232nt
CCTGGACATGGCGCTGAGGGGCCGCCCCGCGGGAAGATGAATAAGGGCTGGCTGGAGCTGGAGAGCGACCCAGGCCTCTTCACCCTGCTC
GTGGAAGATTTCGGTGTCAAGGGGGTGCAAGTGGAGGAGATCTACGACCTTCAGAGCAAATGTCAGGGCCCTGTATATGGATTTATCTTC
CTGTTCAAATGGATCGAAGAGCGCCGGTCCCGGCGAAAGGTCTCTACCTTGGTGGATGATACGTCCGTGATTGATGATGATATTGTGAAT
AACATGTTCTTTGCCCACCAGCTGATACCCAACTCTTGTGCAACTCATGCCTTGCTGAGCGTGCTCCTGAACTGCAGCAGCGTGGACCTG
GGACCCACCCTGAGTCGCATGAAGGACTTCACCAAGGGTTTCAGCCCTGAGAGCAAAGGATATGCGATTGGCAATGCCCCGGAGTTGGCC
AAGGCCCATAATAGCCATGCCAGGCCCGAGCCACGCCACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATGGAGGCGTTC
CACTTTGTCAGCTATGTGCCTATCACAGGCCGGCTCTTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCCTGGGGGGAG
GACGAGGAGTGGACAGACAAGGCCCGGCGGGTCATCATGGAGCGTATCGGCCTCGCCACTGCAGGGATCAAGTATGAGGCCAGGCTGCAT
GTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGATAAGAGTAACACAGCCAGAGCTGATTCAGACCCACAAGTCT
CAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCCGCTGGTGCTGGAAGCAAACAGGGCCCCTGCAGCCTCTGAG
GGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGCCCCATCCCACAGCCCTCCCAACAAACCCAAGCTAGTGGTG
AAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCATTGTCCAGCGGCTGCCGGCCTTTCTAGACAATCACAATTAT
GCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCGCAGCCGAGTTCCAGTCCGCCCACCCCAGCAGTACTCAGAT
GATGAGGATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAACTCTGCCCTTAGAACAAAACTGAAGAATCAAGAATATGAA
ACTTTAGATCATTTGGAGTGTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTT
CTAAAATTGCAGCAAGTTATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCC
ACCTCTGATACTGGTAGTGCCAAAAGAAAAAGGAACACTCATGACAGTGAGATGTTGGGTCTCAGGAGGCTATCCAGTAAAAAGAACATA
AGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGAAGACTTTGTGACCTATTTATGGTT
AAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATAATTGAGCATAACATCCGCAATGAC
AAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTATAATGAGGAGGGCTCCCAGGTTTAT
AATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGATGATGATGACATGGCTTCTCCCAAA
CTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAGAAACTAAATGAGGTCTATGAAGCT
GTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGATCTGAGTTGCCTGACTACTATCTG
ACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGATATTGACTCTATGGTTGAGGACTTT
GTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTTGTTCTACACAAAGTCCTGCTTGAA
ACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAGCTTATCCACAATCTTTTTGTGTCA
GTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTGGATCCCAACTTTCCTAACAAACCA
CCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTTCAAGAGCATATGTTTGAAGTATTG
GAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAGTTTTTTATTAAAATTCGTGATGAA
CTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAATGATGTGGAGAAAGAGAGAAAGGAA
AAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAGAGTGAAGATTCCTCTGGTGCTGCA
GGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTTGGAGATTACGTCTATGTGGAACCT
GCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAAAAATGGTTGTATGGCTGTTGGTTT
TACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTT
AGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTC
TGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGG
GATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGAC
AGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTT
GAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGA
ATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAA
ATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTC
AAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATG
AAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAG
AAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAG
ATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTAC
ACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTG
TTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGA
AATCTTGAGACAGCCAAGAAAGCAGAATATGAAGGTGTGATGAACCAAGGAGTGGCCCCTATGGTAGGGACTCCAGCACCAGGTGGAAGT
CCATATGGACAACAGGTGGGAGTTTTGGGGCCTCCAGGGCAGCAGGCACCACCTCCATATCCCGGCCCACATCCAGCTGGACCCCCTGTC
ATACAGCAGCCAACAACACCCATGTTTGTAGCTCCCCCACCAAAGACCCAGCGGCTTCTTCACTCAGAGGCCTACCTGAAATACATTGAA
GGACTCAGTGCGGAGTCCAACAGCATTAGCAAGTGGGATCAGACACTGGCAGCTCGAAGACGCGACGTCCATTTGTCGAAAGAACAGGAG
AGCCGCCTACCCTCTCACTGGCTGAAAAGCAAAGGGGCCCACACCACCATGGCAGATGCCCTCTGGCGCCTTCGAGATTTGATGCTCCGG
GACACCCTCAACATTCGCCAAGCATACAACCTAGAAAATGTTTAATCACATCATTACGTTTCTTTTATATAGAAGCATAAAGAGTTGTGG

>8972_8972_7_BAP1-PBRM1_BAP1_chr3_52438469_ENST00000296288_PBRM1_chr3_52663051_ENST00000409767_length(amino acids)=1562AA_BP=398
MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVYGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNS
CATHALLSVLLNCSSVDLGPTLSRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRL
FELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGIKYEARLHVLKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKSA
SNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAFLDNHNYAKSPMQEEEDLA
AGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKK
ELARRDDIEDGDSMISSATSDTGSAKRKRNTHDSEMLGLRRLSSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYK
IILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPK
KSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNE
PESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVE
NNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLK
REEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHLATR
KFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASV
FANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAY
FYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLS
AKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKG
SAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPP
GQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKG

--------------------------------------------------------------
>8972_8972_8_BAP1-PBRM1_BAP1_chr3_52438469_ENST00000296288_PBRM1_chr3_52663051_ENST00000410007_length(transcript)=4833nt_BP=1232nt
CCTGGACATGGCGCTGAGGGGCCGCCCCGCGGGAAGATGAATAAGGGCTGGCTGGAGCTGGAGAGCGACCCAGGCCTCTTCACCCTGCTC
GTGGAAGATTTCGGTGTCAAGGGGGTGCAAGTGGAGGAGATCTACGACCTTCAGAGCAAATGTCAGGGCCCTGTATATGGATTTATCTTC
CTGTTCAAATGGATCGAAGAGCGCCGGTCCCGGCGAAAGGTCTCTACCTTGGTGGATGATACGTCCGTGATTGATGATGATATTGTGAAT
AACATGTTCTTTGCCCACCAGCTGATACCCAACTCTTGTGCAACTCATGCCTTGCTGAGCGTGCTCCTGAACTGCAGCAGCGTGGACCTG
GGACCCACCCTGAGTCGCATGAAGGACTTCACCAAGGGTTTCAGCCCTGAGAGCAAAGGATATGCGATTGGCAATGCCCCGGAGTTGGCC
AAGGCCCATAATAGCCATGCCAGGCCCGAGCCACGCCACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATGGAGGCGTTC
CACTTTGTCAGCTATGTGCCTATCACAGGCCGGCTCTTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCCTGGGGGGAG
GACGAGGAGTGGACAGACAAGGCCCGGCGGGTCATCATGGAGCGTATCGGCCTCGCCACTGCAGGGATCAAGTATGAGGCCAGGCTGCAT
GTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGATAAGAGTAACACAGCCAGAGCTGATTCAGACCCACAAGTCT
CAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCCGCTGGTGCTGGAAGCAAACAGGGCCCCTGCAGCCTCTGAG
GGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGCCCCATCCCACAGCCCTCCCAACAAACCCAAGCTAGTGGTG
AAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCATTGTCCAGCGGCTGCCGGCCTTTCTAGACAATCACAATTAT
GCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCGCAGCCGAGTTCCAGTCCGCCCACCCCAGCAGTACTCAGAT
GATGAGGATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAACTCTGCCCTTAGAACAAAACTGAAGAATCAAGAATATGAA
ACTTTAGATCATTTGGAGTGTGATCTGAATTTAATGTTTGAAAATGCCAAACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTT
CTAAAATTGCAGCAAGTTATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAGAGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCC
ACCTCTGATACTGGTAGTGCCAAAAGAAAAAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCT
CGAGAGCCAGGTTCAGGCAGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTG
GAGCCAATGGACTTGAAAATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATG
TTCCGGAATGCCAGGCACTATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAA
GAGCTGGGCCCACTGCCTGATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAA
TACATGACTCCAATGCAGCAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATA
TTTCTGAGGCTTCCCTCTAGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATG
ATGGCCAACAAGTACCAAGATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCT
TTGATCTACAAAGATGCTCTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAAT
GTGACTTTGCTGATTCAAGAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCT
TTAGCAGAAATTCCTGCTGTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGC
TACCGTCGGCTTGATTTATTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAA
GATGCAGTAGAACTTCAGCAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTAT
ACCACAAAACATTTGCATAATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAA
GAAAAAAGAGAAGCTGAAAAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTT
AAAAACAGCATGTACCATGTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTG
TGGGAGGATTCAGCTGAAAAAGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATG
TTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAA
TCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCC
TCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAA
AAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTG
AAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCT
GCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGT
AATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAA
ATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCA
CTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAG
ATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAA
CCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCC
AAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAG
GCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATAT
GAAGGCATGATGGGTGGCTATCCGCCAGGCCTTCCACCTTTGCAGGGCCCAGTTGATGGCCTTGTTAGCATGGGCAGCATGCAGCCACTT
CACCCTGGGGGGCCTCCACCCCACCATCTTCCGCCAGGTGTGCCTGGCCTCCCGGGCATCCCACCACCGGGTGTGATGAACCAAGGAGTG
GCCCCTATGGTAGGGACTCCAGCACCAGGTGGAAGTCCATATGGACAACAGGTGGGAGTTTTGGGGCCTCCAGGGCAGCAGGCACCACCT
CCATATCCCGGCCCACATCCAGCTGGACCCCCTGTCATACAGCAGCCAACAACACCCATGTTTGTAGCTCCCCCACCAAAGACCCAGCGG
CTTCTTCACTCAGAGGCCTACCTGAAATACATTGAAGGACTCAGTGCGGAGTCCAACAGCATTAGCAAGTGGGATCAGACACTGGCAGCT
CGAAGACGCGACGTCCATTTGTCGAAAGAACAGGAGAGCCGCCTACCCTCTCACTGGCTGAAAAGCAAAGGGGCCCACACCACCATGGCA
GATGCCCTCTGGCGCCTTCGAGATTTGATGCTCCGGGACACCCTCAACATTCGCCAAGCATACAACCTAGAAAATGTTTAATCACATCAT

>8972_8972_8_BAP1-PBRM1_BAP1_chr3_52438469_ENST00000296288_PBRM1_chr3_52663051_ENST00000410007_length(amino acids)=1574AA_BP=398
MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVYGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNS
CATHALLSVLLNCSSVDLGPTLSRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRL
FELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGIKYEARLHVLKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKSA
SNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAFLDNHNYAKSPMQEEEDLA
AGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNSAIYKRVLKLQQVMQAKKK
ELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNI
RNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGISPKKSKYMTPMQQKLNEV
YEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACTYNEPESLIYKDALVLHKV
LLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMF
EVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKREAEKSEDSS
GAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPEN
FRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSN
GEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCIL
GKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELE
GGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELS
RLVGTEWRNLETAKKAEYEGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGS
PYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQE

--------------------------------------------------------------
>8972_8972_9_BAP1-PBRM1_BAP1_chr3_52438469_ENST00000460680_PBRM1_chr3_52663051_ENST00000296302_length(transcript)=5564nt_BP=1722nt
CGCTCCGCCCCTCCCCTCGCAGCACCCGGGCCTAGTACTGCCCGTCCCGCCCCTCCTCTCGAGCCTCAGCGCTCAGCATCGCCCGGACCC
CCTCTTCCCTTCGCCCGCCTCGTCCCGACCCTCCCCTTCGCCCCCGTCCCGCCCCGCCCCTCCCCTTCGCCCCCGTCCCGTCCCGCCCCG
CCCCTCCCCTTCGCCCCCGTCCCTCCCCTTCGCCCCCGTCCCTCCGCGCGTGCGCGTTCGCCTTCGAGCGCATGCCCGCATCTGCTGTCC
GACAGGCGGAAGACGAGCCCAGAGGCGGAGCAGGGCCGTCGCGCCTTGGTGACGTCTGCCGCCGGCGCGGGCGGGTGACGCGACTGGGCC
CGTTGTCTGTGTGTGGGACTGAGGGGCCCCGGGGGCGGTGGGGGCTCCCGGTGGGGGCAGCGGTGGGGAGGGAGGGCCTGGACATGGCGC
TGAGGGGCCGCCCCGCGGGAAGATGAATAAGGGCTGGCTGGAGCTGGAGAGCGACCCAGGCCTCTTCACCCTGCTCGTGGAAGATTTCGG
TGTCAAGGGGGTGCAAGTGGAGGAGATCTACGACCTTCAGAGCAAATGTCAGGGCCCTGTATATGGATTTATCTTCCTGTTCAAATGGAT
CGAAGAGCGCCGGTCCCGGCGAAAGGTCTCTACCTTGGTGGATGATACGTCCGTGATTGATGATGATATTGTGAATAACATGTTCTTTGC
CCACCAGCTGATACCCAACTCTTGTGCAACTCATGCCTTGCTGAGCGTGCTCCTGAACTGCAGCAGCGTGGACCTGGGACCCACCCTGAG
TCGCATGAAGGACTTCACCAAGGGTTTCAGCCCTGAGAGCAAAGGATATGCGATTGGCAATGCCCCGGAGTTGGCCAAGGCCCATAATAG
CCATGCCAGGCCCGAGCCACGCCACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATGGAGGCGTTCCACTTTGTCAGCTA
TGTGCCTATCACAGGCCGGCTCTTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCCTGGGGGGAGGACGAGGAGTGGAC
AGACAAGGCCCGGCGGGTCATCATGGAGCGTATCGGCCTCGCCACTGCAGGGGAGCCCTACCACGACATCCGCTTCAACCTGATGGCAGT
GGTGCCCGACCGCAGGATCAAGTATGAGGCCAGGCTGCATGTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGAT
AAGAGTAACACAGCCAGAGCTGATTCAGACCCACAAGTCTCAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCC
GCTGGTGCTGGAAGCAAACAGGGCCCCTGCAGCCTCTGAGGGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGC
CCCATCCCACAGCCCTCCCAACAAACCCAAGCTAGTGGTGAAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCAT
TGTCCAGCGGCTGCCGGCCTTTCTAGACAATCACAATTATGCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCG
CAGCCGAGTTCCAGTCCGCCCACCCCAGCAGTACTCAGATGATGAGGATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAA
CTCTGCCCTTAGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGTGATCTGAATTTAATGTTTGAAAATGCCAA
ACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAG
AGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCCAAAAGAAAAAGTAAAAAGAACATAAGAAA
GCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGAAGACTTTGTGACCTATTTATGGTTAAACC
ATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATAATTGAGCATAACATCCGCAATGACAAATA
TGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTATAATGAGGAGGGCTCCCAGGTTTATAATGA
TGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGATGATGATGACATGGCTTCTCCCAAACTCAA
GCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAGAAACTAAATGAGGTCTATGAAGCTGTAAA
GAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGATCTGAGTTGCCTGACTACTATCTGACTAT
TAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGATATTGACTCTATGGTTGAGGACTTTGTCAT
GATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTTGTTCTACACAAAGTCCTGCTTGAAACACG
CAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAGCTTATCCACAATCTTTTTGTGTCAGTCAT
GAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTGGATCCCAACTTTCCTAACAAACCACCCCT
TACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTTCAAGAGCATATGTTTGAAGTATTGGAACG
AGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAGTTTTTTATTAAAATTCGTGATGAACTCTG
CAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAATGATGTGGAGAAAGAGAGAAAGGAAAAATT
GCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAGAGTGAAGATTCCTCTGGTGCTGCAGGCCT
CTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTTGGAGATTACGTCTATGTGGAACCTGCAGA
GGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAAAAATGGTTGTATGGCTGTTGGTTTTACCG
ACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAA
AATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGA
ATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGT
GCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCG
AGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCA
GCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGA
AAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTT
CTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGA
CTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAA
ATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGA
GCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGG
AGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACC
CCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAG
CAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCT
TGAGACAGCCAAGAAAGCAGAATATGAAGAGCGGGCAGCTAAAGTTGCTGAGCAGCAGGAGAGAGAGCGAGCAGCACAGCAACAGCAGCC
GAGTGCTTCTCCCCGAGCAGGCACCCCTGTGGGGGCTCTCATGGGGGTGGTGCCACCACCAACACCAATGGGGATGCTCAATCAGCAGTT
GACACCTGTTGCAGGCATGATGGGTGGCTATCCGCCAGGCCTTCCACCTTTGCAGGGCCCAGTTGATGGCCTTGTTAGCATGGGCAGCAT
GCAGCCACTTCACCCTGGGGGGCCTCCACCCCACCATCTTCCGCCAGGTGTGCCTGGCCTCCCGGGCATCCCACCACCGGGTGTGATGAA
CCAAGGAGTGGCCCCTATGGTAGGGACTCCAGCACCAGGTGGAAGTCCATATGGACAACAGGTGGGAGTTTTGGGGCCTCCAGGGCAGCA
GGCACCACCTCCATATCCCGGCCCACATCCAGCTGGACCCCCTGTCATACAGCAGCCAACAACACCCATGTTTGTAGCTCCCCCACCAAA
GACCCAGCGGCTTCTTCACTCAGAGGCCTACCTGAAATACATTGAAGGACTCAGTGCGGAGTCCAACAGCATTAGCAAGTGGGATCAGAC
ACTGGCAGCTCGAAGACGCGACGTCCATTTGTCGAAAGAACAGGAGAGCCGCCTACCCTCTCACTGGCTGAAAAGCAAAGGGGCCCACAC
CACCATGGCAGATGCCCTCTGGCGCCTTCGAGATTTGATGCTCCGGGACACCCTCAACATTCGCCAAGCATACAACCTAGAAAATGTTTA

>8972_8972_9_BAP1-PBRM1_BAP1_chr3_52438469_ENST00000460680_PBRM1_chr3_52663051_ENST00000296302_length(amino acids)=1672AA_BP=416
MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVYGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNS
CATHALLSVLLNCSSVDLGPTLSRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRL
FELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRIKYEARLHVLKVNRQTVLEALQQLIRVTQPEL
IQTHKSQESQLPEESKSASNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAF
LDNHNYAKSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNS
AIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPD
YYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGI
SPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACT
YNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRK
NVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEED
KLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHL
ATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRV
ASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDG
AAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRF
SLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKS
AKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEERAAKVAEQQERERAAQQQQPSASPRAG
TPVGALMGVVPPPTPMGMLNQQLTPVAGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMV
GTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRD

--------------------------------------------------------------
>8972_8972_10_BAP1-PBRM1_BAP1_chr3_52438469_ENST00000460680_PBRM1_chr3_52663051_ENST00000337303_length(transcript)=5243nt_BP=1722nt
CGCTCCGCCCCTCCCCTCGCAGCACCCGGGCCTAGTACTGCCCGTCCCGCCCCTCCTCTCGAGCCTCAGCGCTCAGCATCGCCCGGACCC
CCTCTTCCCTTCGCCCGCCTCGTCCCGACCCTCCCCTTCGCCCCCGTCCCGCCCCGCCCCTCCCCTTCGCCCCCGTCCCGTCCCGCCCCG
CCCCTCCCCTTCGCCCCCGTCCCTCCCCTTCGCCCCCGTCCCTCCGCGCGTGCGCGTTCGCCTTCGAGCGCATGCCCGCATCTGCTGTCC
GACAGGCGGAAGACGAGCCCAGAGGCGGAGCAGGGCCGTCGCGCCTTGGTGACGTCTGCCGCCGGCGCGGGCGGGTGACGCGACTGGGCC
CGTTGTCTGTGTGTGGGACTGAGGGGCCCCGGGGGCGGTGGGGGCTCCCGGTGGGGGCAGCGGTGGGGAGGGAGGGCCTGGACATGGCGC
TGAGGGGCCGCCCCGCGGGAAGATGAATAAGGGCTGGCTGGAGCTGGAGAGCGACCCAGGCCTCTTCACCCTGCTCGTGGAAGATTTCGG
TGTCAAGGGGGTGCAAGTGGAGGAGATCTACGACCTTCAGAGCAAATGTCAGGGCCCTGTATATGGATTTATCTTCCTGTTCAAATGGAT
CGAAGAGCGCCGGTCCCGGCGAAAGGTCTCTACCTTGGTGGATGATACGTCCGTGATTGATGATGATATTGTGAATAACATGTTCTTTGC
CCACCAGCTGATACCCAACTCTTGTGCAACTCATGCCTTGCTGAGCGTGCTCCTGAACTGCAGCAGCGTGGACCTGGGACCCACCCTGAG
TCGCATGAAGGACTTCACCAAGGGTTTCAGCCCTGAGAGCAAAGGATATGCGATTGGCAATGCCCCGGAGTTGGCCAAGGCCCATAATAG
CCATGCCAGGCCCGAGCCACGCCACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATGGAGGCGTTCCACTTTGTCAGCTA
TGTGCCTATCACAGGCCGGCTCTTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCCTGGGGGGAGGACGAGGAGTGGAC
AGACAAGGCCCGGCGGGTCATCATGGAGCGTATCGGCCTCGCCACTGCAGGGGAGCCCTACCACGACATCCGCTTCAACCTGATGGCAGT
GGTGCCCGACCGCAGGATCAAGTATGAGGCCAGGCTGCATGTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGAT
AAGAGTAACACAGCCAGAGCTGATTCAGACCCACAAGTCTCAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCC
GCTGGTGCTGGAAGCAAACAGGGCCCCTGCAGCCTCTGAGGGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGC
CCCATCCCACAGCCCTCCCAACAAACCCAAGCTAGTGGTGAAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCAT
TGTCCAGCGGCTGCCGGCCTTTCTAGACAATCACAATTATGCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCG
CAGCCGAGTTCCAGTCCGCCCACCCCAGCAGTACTCAGATGATGAGGATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAA
CTCTGCCCTTAGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGTGATCTGAATTTAATGTTTGAAAATGCCAA
ACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAG
AGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCCAAAAGAAAAAGTAAAAAGAACATAAGAAA
GCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGAAGACTTTGTGACCTATTTATGGTTAAACC
ATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATAATTGAGCATAACATCCGCAATGACAAATA
TGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTATAATGAGGAGGGCTCCCAGGTTTATAATGA
TGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGATGATGATGACATGGCTTCTCCCAAACTCAA
GCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAGAAACTAAATGAGGTCTATGAAGCTGTAAA
GAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGATCTGAGTTGCCTGACTACTATCTGACTAT
TAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGATATTGACTCTATGGTTGAGGACTTTGTCAT
GATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTTGTTCTACACAAAGTCCTGCTTGAAACACG
CAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAGCTTATCCACAATCTTTTTGTGTCAGTCAT
GAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTGGATCCCAACTTTCCTAACAAACCACCCCT
TACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTTCAAGAGCATATGTTTGAAGTATTGGAACG
AGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAGTTTTTTATTAAAATTCGTGATGAACTCTG
CAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAATGATGTGGAGAAAGAGAGAAAGGAAAAATT
GCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAGAGTGAAGATTCCTCTGGTGCTGCAGGCCT
CTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTTGGAGATTACGTCTATGTGGAACCTGCAGA
GGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAAAAATGGTTGTATGGCTGTTGGTTTTACCG
ACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAA
AATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGA
ATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGT
GCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCG
AGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCA
GCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGA
AAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTT
CTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGA
CTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAA
ATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGA
GCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGG
AGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACC
CCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAG
CAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCT
TGAGACAGCCAAGAAAGCAGAATATGAAGGTGTGATGAACCAAGGAGTGGCCCCTATGGTAGGGACTCCAGCACCAGGTGGAAGTCCATA
TGGACAACAGGTGGGAGTTTTGGGGCCTCCAGGGCAGCAGGCACCACCTCCATATCCCGGCCCACATCCAGCTGGACCCCCTGTCATACA
GCAGCCAACAACACCCATGTTTGTAGCTCCCCCACCAAAGACCCAGCGGCTTCTTCACTCAGAGGCCTACCTGAAATACATTGAAGGACT
CAGTGCGGAGTCCAACAGCATTAGCAAGTGGGATCAGACACTGGCAGCTCGAAGACGCGACGTCCATTTGTCGAAAGAACAGGAGAGCCG
CCTACCCTCTCACTGGCTGAAAAGCAAAGGGGCCCACACCACCATGGCAGATGCCCTCTGGCGCCTTCGAGATTTGATGCTCCGGGACAC
CCTCAACATTCGCCAAGCATACAACCTAGAAAATGTTTAATCACATCATTACGTTTCTTTTATATAGAAGCATAAAGAGTTGTGGATCAG

>8972_8972_10_BAP1-PBRM1_BAP1_chr3_52438469_ENST00000460680_PBRM1_chr3_52663051_ENST00000337303_length(amino acids)=1565AA_BP=416
MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVYGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNS
CATHALLSVLLNCSSVDLGPTLSRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRL
FELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRIKYEARLHVLKVNRQTVLEALQQLIRVTQPEL
IQTHKSQESQLPEESKSASNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAF
LDNHNYAKSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNS
AIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPD
YYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGI
SPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACT
YNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRK
NVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEED
KLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHL
ATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRV
ASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDG
AAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRF
SLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKS
AKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGVMNQGVAPMVGTPAPGGSPYGQQVGVL
GPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLK

--------------------------------------------------------------
>8972_8972_11_BAP1-PBRM1_BAP1_chr3_52438469_ENST00000460680_PBRM1_chr3_52663051_ENST00000356770_length(transcript)=8037nt_BP=1722nt
CGCTCCGCCCCTCCCCTCGCAGCACCCGGGCCTAGTACTGCCCGTCCCGCCCCTCCTCTCGAGCCTCAGCGCTCAGCATCGCCCGGACCC
CCTCTTCCCTTCGCCCGCCTCGTCCCGACCCTCCCCTTCGCCCCCGTCCCGCCCCGCCCCTCCCCTTCGCCCCCGTCCCGTCCCGCCCCG
CCCCTCCCCTTCGCCCCCGTCCCTCCCCTTCGCCCCCGTCCCTCCGCGCGTGCGCGTTCGCCTTCGAGCGCATGCCCGCATCTGCTGTCC
GACAGGCGGAAGACGAGCCCAGAGGCGGAGCAGGGCCGTCGCGCCTTGGTGACGTCTGCCGCCGGCGCGGGCGGGTGACGCGACTGGGCC
CGTTGTCTGTGTGTGGGACTGAGGGGCCCCGGGGGCGGTGGGGGCTCCCGGTGGGGGCAGCGGTGGGGAGGGAGGGCCTGGACATGGCGC
TGAGGGGCCGCCCCGCGGGAAGATGAATAAGGGCTGGCTGGAGCTGGAGAGCGACCCAGGCCTCTTCACCCTGCTCGTGGAAGATTTCGG
TGTCAAGGGGGTGCAAGTGGAGGAGATCTACGACCTTCAGAGCAAATGTCAGGGCCCTGTATATGGATTTATCTTCCTGTTCAAATGGAT
CGAAGAGCGCCGGTCCCGGCGAAAGGTCTCTACCTTGGTGGATGATACGTCCGTGATTGATGATGATATTGTGAATAACATGTTCTTTGC
CCACCAGCTGATACCCAACTCTTGTGCAACTCATGCCTTGCTGAGCGTGCTCCTGAACTGCAGCAGCGTGGACCTGGGACCCACCCTGAG
TCGCATGAAGGACTTCACCAAGGGTTTCAGCCCTGAGAGCAAAGGATATGCGATTGGCAATGCCCCGGAGTTGGCCAAGGCCCATAATAG
CCATGCCAGGCCCGAGCCACGCCACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATGGAGGCGTTCCACTTTGTCAGCTA
TGTGCCTATCACAGGCCGGCTCTTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCCTGGGGGGAGGACGAGGAGTGGAC
AGACAAGGCCCGGCGGGTCATCATGGAGCGTATCGGCCTCGCCACTGCAGGGGAGCCCTACCACGACATCCGCTTCAACCTGATGGCAGT
GGTGCCCGACCGCAGGATCAAGTATGAGGCCAGGCTGCATGTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGAT
AAGAGTAACACAGCCAGAGCTGATTCAGACCCACAAGTCTCAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCC
GCTGGTGCTGGAAGCAAACAGGGCCCCTGCAGCCTCTGAGGGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGC
CCCATCCCACAGCCCTCCCAACAAACCCAAGCTAGTGGTGAAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCAT
TGTCCAGCGGCTGCCGGCCTTTCTAGACAATCACAATTATGCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCG
CAGCCGAGTTCCAGTCCGCCCACCCCAGCAGTACTCAGATGATGAGGATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAA
CTCTGCCCTTAGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGTGATCTGAATTTAATGTTTGAAAATGCCAA
ACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAG
AGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCCAAAAGAAAAAGTAAAAAGAACATAAGAAA
GCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGAAGACTTTGTGACCTATTTATGGTTAAACC
ATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATAATTGAGCATAACATCCGCAATGACAAATA
TGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTATAATGAGGAGGGCTCCCAGGTTTATAATGA
TGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGATGATGATGACATGGCTTCTCCCAAACTCAA
GCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAGAAACTAAATGAGGTCTATGAAGCTGTAAA
GAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGATCTGAGTTGCCTGACTACTATCTGACTAT
TAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGATATTGACTCTATGGTTGAGGACTTTGTCAT
GATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTTGTTCTACACAAAGTCCTGCTTGAAACACG
CAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAGCTTATCCACAATCTTTTTGTGTCAGTCAT
GAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTGGATCCCAACTTTCCTAACAAACCACCCCT
TACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTTCAAGAGCATATGTTTGAAGTATTGGAACG
AGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAGTTTTTTATTAAAATTCGTGATGAACTCTG
CAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAATGATGTGGAGAAAGAGAGAAAGGAAAAATT
GCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAGAGTGAAGATTCCTCTGGTGCTGCAGGCCT
CTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTTGGAGATTACGTCTATGTGGAACCTGCAGA
GGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAAAAATGGTTGTATGGCTGTTGGTTTTACCG
ACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAA
AATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGA
ATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGT
GCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCG
AGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCA
GCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGA
AAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTT
CTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGA
CTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAA
ATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGA
GCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGG
AGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACC
CCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAG
CAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCT
TGAGACAGCCAAGAAAGCAGAATATGAAGGCATGATGGGTGGCTATCCGCCAGGCCTTCCACCTTTGCAGGGCCCAGTTGATGGCCTTGT
TAGCATGGGCAGCATGCAGCCACTTCACCCTGGGGGGCCTCCACCCCACCATCTTCCGCCAGGTGTGCCTGGCCTCCCGGGCATCCCACC
ACCGGGTGTGATGAACCAAGGAGTGGCCCCTATGGTAGGGACTCCAGCACCAGGTGGAAGTCCATATGGACAACAGGTGGGAGTTTTGGG
GCCTCCAGGGCAGCAGGCACCACCTCCATATCCCGGCCCACATCCAGCTGGACCCCCTGTCATACAGCAGCCAACAACACCCATGTTTGT
AGCTCCCCCACCAAAGACCCAGCGGCTTCTTCACTCAGAGGCCTACCTGAAATACATTGAAGGACTCAGTGCGGAGTCCAACAGCATTAG
CAAGTGGGATCAGACACTGGCAGCTCGAAGACGCGACGTCCATTTGTCGAAAGAACAGGAGAGCCGCCTACCCTCTCACTGGCTGAAAAG
CAAAGGGGCCCACACCACCATGGCAGATGCCCTCTGGCGCCTTCGAGATTTGATGCTCCGGGACACCCTCAACATTCGCCAAGCATACAA
CCTAGAAAATGTTTAATCACATCATTACGTTTCTTTTATATAGAAGCATAAAGAGTTGTGGATCAGTAGCCATTTTAGTTACTGGGGGTG
GGGGGAAGGAACAAAGGAGGATAATTTTTATTGCATTTTACTGTACATCACAAGGCCATTTTTATATACGGACACTTTTAATAAGCTATT
TCAATTTGTTTGTTATATTAAGTTGACTTTATCAAATACACAAAGATTTTTTTGCATATGTTTCCTTCGTTTAAAACCAGTTTCATAATT
GGTTGTATATGTAGACTTGGAGTTTTATCTTTTTACTTGTTGCCATGGAACTGAAACCATTAGAGGTTTTTGTCTTGGCTTGGGGTTTTT
GTTTTCTTGGTTTTGGGTTTTTTTATATATATATATAAAAGAACAAAATGAAAAAAAACACACACACACAAGAGTTTACAGATTAGTTTA
AATTGATAATGAAATGTGAAGTTTGTCCTAGTTTACATCTTAGAGAGGGGAGTATACTTGTGTTTGTTTCATGTGCCTGAATATCTTAAG
CCACTTTCTGCAAAAGCTGTTTCTTACAGATGAAGTGCTTTCTTTGAAAGGTGGTTATTTAGGTTTTAGATGTTTAATAGACACAGCACA
TTTGCTCTATTAACTCAGAGGCTCACTACAGAAATATGTAATCAGTGCTGTGCATCTGTCTGCAGCTAATGTACCTCCTGGACACCAGGA
GGGGAAAAAGCACTTTTTCAATTGTGCTGAGTTAGACATCTGTGAGTTAGACTATGGTGTCAGTGATTTTTGCAGAACACGTGCACAACC
CTGAGGTATGTTTAATCTAGGCAGGTACGTTTAAGGATATTTTGATCTATTTATAATGAATTCACAATTTATGCCTATAAATTTCAGATG
ATTTAAAATTTTAAACCTGTTACATTGAAAAACATTGAAGTTCGTCTTGAAGAAAGCATTAAGGTATGCATGGAGGTGATTTATTTTTAA
ACATAACACCTAACCTAACATGGGTAAGAGAGTATGGAACTAGATATGAGCTGTATAAGAAGCATAATTGTGAACAAGTAGATTGATTGC
CTTCATATACAAGTATGTTTTAGTATTCCTTATTTCCTTATTATCAGATGTATTTTTTCTTTTAAGTTTCAATGTTGTTATAATTCTCAA
CCAGAAATTTAATACTTTCTAAAATATTTTTTAAATTTAGCTTGTGCTTTTGAATTACAGGAGAAGGGAATCATAATTTAATAAAACGCT
TACTAGAAAGACCATTACAGATCCCAAACACTTGGGTTTGGTGACCCTGTCTTTCTTATATGACCCTACAATAAACATTTGAAGGCAGCA
TAGGATGGCAGACAGTAGGAACATTGTTTCACTTGGCGGCATGTTTTTGAAACCTGCTTTATAGTAACTGGGTGATTGCCATTGTGGTAG
AGCTTCCACTGCTGTTTATAATCTGAGAGAGTTAATCTCAGAGGATGCTTTTTTCCTTTTAATCTGCTATGAATCAGTACCCAGATGTTT
AATTACTGTACTTATTAAATCATGAGGGCAAAAGAGTGTAGAATGGAAAAAAGTCTCTTGTATCTAGATACTTTAAATATGGGAGGCCCT
TTAACTTAATTGCCTTTAGTCAACCACTGGATTTGAATTTGCATCAAGTATTTTAAATAATATTGAATTTAAAAAAATGTATTGCAGTAG
TGTGTCAGTACCTTATTGTTAAAGTGAGTCAGATAAATCTTCAATTCCTGGCTATTTGGGCAATTGAATCATCATGGACTGTATAATGCA
ATCAGATTATTTTGTTTCTAGACATCCTTGAATTACACCAAAGAACATGAAATTTAGTTGTGGTTAAATTATTTATTTATTTCATGCATT
CATTTTATTTCCCTTAAGGTCTGGATGAGACTTCTTTGGGGAGCCTCTAAAAAAATTTTTCACTGGGGGCCACGTGGGTCATTAGAAGCC
AGAGCTCTCCTCCAGGCTCCTTCCCAGTGCCTAGAGGTGCTATAGGAAACATAGATCCAGCCAGGGGCTTCCCTAAAGCAGTGCAGCACC
GGCCCAGGGCATCACTAGACAGGCCCTAATTAAGTTTTTTTTAAAAAGCCTGTGTATTTATTTTAGAATCATGTTTTTCTGTATATTAAC
TTGGGGGATATCGTTAATATTTAGGATATAAGATTTGAGGTCAGCCATCTTCAAAAAAGAAAAAAAAATTGACTCAAGAAAGTACAAGTA
AACTATACACCTTTTTTTCATAAGTTTTAGGAACTGTAGTAATGTGGCTTAGAAAGTATAATGGCCTAAATGTTTTCAAAATGTAAGTTC
CTGTGGAGAAGAATTGTTTATATTGCAAACGGGGGGACTGAGGGGAACCTGTAGGTTTAAAACAGTATGTTTGTCAGCCAACTGATTTAA
AAGGCCTTTAACTGTTTTGGTTGTTGTTTTTTTTTTAAGCCACTCTCCCCTTCCTATGAGGAAGAATTGAGAGGGGCACCTATTTCTGTA
AAATCCCCAAATTGGTGTTGATGATTTTGAGCTTGAATGTTTTCATACCTGATTAAAACTTGGTTTATTCTAATTTCTGTATCATATCAT
CTGAGGTTTACGTGGTAACTAGTCTTATAACATGTATGTATCTTTTTTTTGTTGTTCATCTAAAGCTTTTTAATCCAAATAAATACAGAG

>8972_8972_11_BAP1-PBRM1_BAP1_chr3_52438469_ENST00000460680_PBRM1_chr3_52663051_ENST00000356770_length(amino acids)=1617AA_BP=416
MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVYGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNS
CATHALLSVLLNCSSVDLGPTLSRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRL
FELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRIKYEARLHVLKVNRQTVLEALQQLIRVTQPEL
IQTHKSQESQLPEESKSASNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAF
LDNHNYAKSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNS
AIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPD
YYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGI
SPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACT
YNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRK
NVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEED
KLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHL
ATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRV
ASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDG
AAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRF
SLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKS
AKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGMMGGYPPGLPPLQGPVDGLVSMGSMQP
LHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQ

--------------------------------------------------------------
>8972_8972_12_BAP1-PBRM1_BAP1_chr3_52438469_ENST00000460680_PBRM1_chr3_52663051_ENST00000394830_length(transcript)=5392nt_BP=1722nt
CGCTCCGCCCCTCCCCTCGCAGCACCCGGGCCTAGTACTGCCCGTCCCGCCCCTCCTCTCGAGCCTCAGCGCTCAGCATCGCCCGGACCC
CCTCTTCCCTTCGCCCGCCTCGTCCCGACCCTCCCCTTCGCCCCCGTCCCGCCCCGCCCCTCCCCTTCGCCCCCGTCCCGTCCCGCCCCG
CCCCTCCCCTTCGCCCCCGTCCCTCCCCTTCGCCCCCGTCCCTCCGCGCGTGCGCGTTCGCCTTCGAGCGCATGCCCGCATCTGCTGTCC
GACAGGCGGAAGACGAGCCCAGAGGCGGAGCAGGGCCGTCGCGCCTTGGTGACGTCTGCCGCCGGCGCGGGCGGGTGACGCGACTGGGCC
CGTTGTCTGTGTGTGGGACTGAGGGGCCCCGGGGGCGGTGGGGGCTCCCGGTGGGGGCAGCGGTGGGGAGGGAGGGCCTGGACATGGCGC
TGAGGGGCCGCCCCGCGGGAAGATGAATAAGGGCTGGCTGGAGCTGGAGAGCGACCCAGGCCTCTTCACCCTGCTCGTGGAAGATTTCGG
TGTCAAGGGGGTGCAAGTGGAGGAGATCTACGACCTTCAGAGCAAATGTCAGGGCCCTGTATATGGATTTATCTTCCTGTTCAAATGGAT
CGAAGAGCGCCGGTCCCGGCGAAAGGTCTCTACCTTGGTGGATGATACGTCCGTGATTGATGATGATATTGTGAATAACATGTTCTTTGC
CCACCAGCTGATACCCAACTCTTGTGCAACTCATGCCTTGCTGAGCGTGCTCCTGAACTGCAGCAGCGTGGACCTGGGACCCACCCTGAG
TCGCATGAAGGACTTCACCAAGGGTTTCAGCCCTGAGAGCAAAGGATATGCGATTGGCAATGCCCCGGAGTTGGCCAAGGCCCATAATAG
CCATGCCAGGCCCGAGCCACGCCACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATGGAGGCGTTCCACTTTGTCAGCTA
TGTGCCTATCACAGGCCGGCTCTTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCCTGGGGGGAGGACGAGGAGTGGAC
AGACAAGGCCCGGCGGGTCATCATGGAGCGTATCGGCCTCGCCACTGCAGGGGAGCCCTACCACGACATCCGCTTCAACCTGATGGCAGT
GGTGCCCGACCGCAGGATCAAGTATGAGGCCAGGCTGCATGTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGAT
AAGAGTAACACAGCCAGAGCTGATTCAGACCCACAAGTCTCAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCC
GCTGGTGCTGGAAGCAAACAGGGCCCCTGCAGCCTCTGAGGGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGC
CCCATCCCACAGCCCTCCCAACAAACCCAAGCTAGTGGTGAAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCAT
TGTCCAGCGGCTGCCGGCCTTTCTAGACAATCACAATTATGCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCG
CAGCCGAGTTCCAGTCCGCCCACCCCAGCAGTACTCAGATGATGAGGATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAA
CTCTGCCCTTAGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGTGATCTGAATTTAATGTTTGAAAATGCCAA
ACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAG
AGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCCAAAAGAAAAAGTAAAAAGAACATAAGAAA
GCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGAAGACTTTGTGACCTATTTATGGTTAAACC
ATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATAATTGAGCATAACATCCGCAATGACAAATA
TGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTATAATGAGGAGGGCTCCCAGGTTTATAATGA
TGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGATGATGATGACATGGCTTCTCCCAAACTCAA
GCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAGAAACTAAATGAGGTCTATGAAGCTGTAAA
GAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGATCTGAGTTGCCTGACTACTATCTGACTAT
TAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGATATTGACTCTATGGTTGAGGACTTTGTCAT
GATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTTGTTCTACACAAAGTCCTGCTTGAAACACG
CAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAGCTTATCCACAATCTTTTTGTGTCAGTCAT
GAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTGGATCCCAACTTTCCTAACAAACCACCCCT
TACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTTCAAGAGCATATGTTTGAAGTATTGGAACG
AGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAGTTTTTTATTAAAATTCGTGATGAACTCTG
CAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAATGATGTGGAGAAAGAGAGAAAGGAAAAATT
GCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAGAGTGAAGATTCCTCTGGTGCTGCAGGCCT
CTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTTGGAGATTACGTCTATGTGGAACCTGCAGA
GGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGAAAAAGAAGTTTTTAAGAGTGACTATTACAACAA
AGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTCCGAGATGAGGA
TGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGCTCAGTCAGGTT
TGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAGAATACAGACAA
CTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGTGAACCAGGTTG
CCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTGGTGCGTCCTCG
TGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAAACAGAGCATGA
GCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGAAAGTGTGCTGT
GTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTACAATGAGAGCGA
CAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTCAGAAAACCAAT
TGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGTGGAGATGATGA
TATTGAAGAGATGGGAGAAGAAGATAGTGAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATCAA
CATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGCCT
GGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGGCATGATGGGTGGCTATCCGCCAGGCCTTCCACCTTT
GCAGGGCCCAGTTGATGGCCTTGTTAGCATGGGCAGCATGCAGCCACTTCACCCTGGGGGGCCTCCACCCCACCATCTTCCGCCAGGTGT
GCCTGGCCTCCCGGGCATCCCACCACCGGGTGTGATGAACCAAGGAGTGGCCCCTATGGTAGGGACTCCAGCACCAGGTGGAAGTCCATA
TGGACAACAGGTGGGAGTTTTGGGGCCTCCAGGGCAGCAGGCACCACCTCCATATCCCGGCCCACATCCAGCTGGACCCCCTGTCATACA
GCAGCCAACAACACCCATGTTTGTAGCTCCCCCACCAAAGACCCAGCGGCTTCTTCACTCAGAGGCCTACCTGAAATACATTGAAGGACT
CAGTGCGGAGTCCAACAGCATTAGCAAGTGGGATCAGACACTGGCAGCTCGAAGACGCGACGTCCATTTGTCGAAAGAACAGGAGAGCCG
CCTACCCTCTCACTGGCTGAAAAGCAAAGGGGCCCACACCACCATGGCAGATGCCCTCTGGCGCCTTCGAGATTTGATGCTCCGGGACAC
CCTCAACATTCGCCAAGCATACAACCTAGAAAATGTTTAATCACATCATTACGTTTCTTTTATATAGAAGCATAAAGAGTTGTGGATCAG
TAGCCATTTTAGTTACTGGGGGTGGGGGGAAGGAACAAAGGAGGATAATTTTTATTGCATTTTACTGTACATCACAAGGCCATTTTTATA

>8972_8972_12_BAP1-PBRM1_BAP1_chr3_52438469_ENST00000460680_PBRM1_chr3_52663051_ENST00000394830_length(amino acids)=1565AA_BP=416
MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVYGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNS
CATHALLSVLLNCSSVDLGPTLSRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRL
FELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRIKYEARLHVLKVNRQTVLEALQQLIRVTQPEL
IQTHKSQESQLPEESKSASNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAF
LDNHNYAKSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNS
AIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPD
YYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGI
SPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACT
YNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRK
NVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEED
KLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAEKEVFKSDYYNKVPVSKIL
GKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAE
DNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYK
KEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPS
PLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSESTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRN
LETAKKAEYEGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVL
GPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLK

--------------------------------------------------------------
>8972_8972_13_BAP1-PBRM1_BAP1_chr3_52438469_ENST00000460680_PBRM1_chr3_52663051_ENST00000409057_length(transcript)=5398nt_BP=1722nt
CGCTCCGCCCCTCCCCTCGCAGCACCCGGGCCTAGTACTGCCCGTCCCGCCCCTCCTCTCGAGCCTCAGCGCTCAGCATCGCCCGGACCC
CCTCTTCCCTTCGCCCGCCTCGTCCCGACCCTCCCCTTCGCCCCCGTCCCGCCCCGCCCCTCCCCTTCGCCCCCGTCCCGTCCCGCCCCG
CCCCTCCCCTTCGCCCCCGTCCCTCCCCTTCGCCCCCGTCCCTCCGCGCGTGCGCGTTCGCCTTCGAGCGCATGCCCGCATCTGCTGTCC
GACAGGCGGAAGACGAGCCCAGAGGCGGAGCAGGGCCGTCGCGCCTTGGTGACGTCTGCCGCCGGCGCGGGCGGGTGACGCGACTGGGCC
CGTTGTCTGTGTGTGGGACTGAGGGGCCCCGGGGGCGGTGGGGGCTCCCGGTGGGGGCAGCGGTGGGGAGGGAGGGCCTGGACATGGCGC
TGAGGGGCCGCCCCGCGGGAAGATGAATAAGGGCTGGCTGGAGCTGGAGAGCGACCCAGGCCTCTTCACCCTGCTCGTGGAAGATTTCGG
TGTCAAGGGGGTGCAAGTGGAGGAGATCTACGACCTTCAGAGCAAATGTCAGGGCCCTGTATATGGATTTATCTTCCTGTTCAAATGGAT
CGAAGAGCGCCGGTCCCGGCGAAAGGTCTCTACCTTGGTGGATGATACGTCCGTGATTGATGATGATATTGTGAATAACATGTTCTTTGC
CCACCAGCTGATACCCAACTCTTGTGCAACTCATGCCTTGCTGAGCGTGCTCCTGAACTGCAGCAGCGTGGACCTGGGACCCACCCTGAG
TCGCATGAAGGACTTCACCAAGGGTTTCAGCCCTGAGAGCAAAGGATATGCGATTGGCAATGCCCCGGAGTTGGCCAAGGCCCATAATAG
CCATGCCAGGCCCGAGCCACGCCACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATGGAGGCGTTCCACTTTGTCAGCTA
TGTGCCTATCACAGGCCGGCTCTTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCCTGGGGGGAGGACGAGGAGTGGAC
AGACAAGGCCCGGCGGGTCATCATGGAGCGTATCGGCCTCGCCACTGCAGGGGAGCCCTACCACGACATCCGCTTCAACCTGATGGCAGT
GGTGCCCGACCGCAGGATCAAGTATGAGGCCAGGCTGCATGTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGAT
AAGAGTAACACAGCCAGAGCTGATTCAGACCCACAAGTCTCAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCC
GCTGGTGCTGGAAGCAAACAGGGCCCCTGCAGCCTCTGAGGGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGC
CCCATCCCACAGCCCTCCCAACAAACCCAAGCTAGTGGTGAAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCAT
TGTCCAGCGGCTGCCGGCCTTTCTAGACAATCACAATTATGCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCG
CAGCCGAGTTCCAGTCCGCCCACCCCAGCAGTACTCAGATGATGAGGATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAA
CTCTGCCCTTAGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGTGATCTGAATTTAATGTTTGAAAATGCCAA
ACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAG
AGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCCAAAAGAAAAAGTAAAAAGAACATAAGAAA
GCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGAAGACTTTGTGACCTATTTATGGTTAAACC
ATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATAATTGAGCATAACATCCGCAATGACAAATA
TGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTATAATGAGGAGGGCTCCCAGGTTTATAATGA
TGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGATGATGATGACATGGCTTCTCCCAAACTCAA
GCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAGAAACTAAATGAGGTCTATGAAGCTGTAAA
GAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGATCTGAGTTGCCTGACTACTATCTGACTAT
TAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGATATTGACTCTATGGTTGAGGACTTTGTCAT
GATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTTGTTCTACACAAAGTCCTGCTTGAAACACG
CAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAGCTTATCCACAATCTTTTTGTGTCAGTCAT
GAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTGGATCCCAACTTTCCTAACAAACCACCCCT
TACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTTCAAGAGCATATGTTTGAAGTATTGGAACG
AGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAGTTTTTTATTAAAATTCGTGATGAACTCTG
CAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAATGATGTGGAGAAAGAGAGAAAGGAAAAATT
GCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAGAGTGAAGATTCCTCTGGTGCTGCAGGCCT
CTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTTGGAGATTACGTCTATGTGGAACCTGCAGA
GGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGGTGAAAAATGGTTGTATGGCTGTTGGTTTTACCG
ACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAAAGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAA
AATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGA
ATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGT
GCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCG
AGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCA
GCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGA
AAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTT
CTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGA
CTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAA
ATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGA
GCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGG
AGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACC
CCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAG
CAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCT
TGAGACAGCCAAGAAAGCAGAATATGAAGGCATGATGGGTGGCTATCCGCCAGGCCTTCCACCTTTGCAGGGCCCAGTTGATGGCCTTGT
TAGCATGGGCAGCATGCAGCCACTTCACCCTGGGGGGCCTCCACCCCACCATCTTCCGCCAGGTGTGCCTGGCCTCCCGGGCATCCCACC
ACCGGGTGTGATGAACCAAGGAGTGGCCCCTATGGTAGGGACTCCAGCACCAGGTGGAAGTCCATATGGACAACAGGTGGGAGTTTTGGG
GCCTCCAGGGCAGCAGGCACCACCTCCATATCCCGGCCCACATCCAGCTGGACCCCCTGTCATACAGCAGCCAACAACACCCATGTTTGT
AGCTCCCCCACCAAAGACCCAGCGGCTTCTTCACTCAGAGGCCTACCTGAAATACATTGAAGGACTCAGTGCGGAGTCCAACAGCATTAG
CAAGTGGGATCAGACACTGGCAGCTCGAAGACGCGACGTCCATTTGTCGAAAGAACAGGAGAGCCGCCTACCCTCTCACTGGCTGAAAAG
CAAAGGGGCCCACACCACCATGGCAGATGCCCTCTGGCGCCTTCGAGATTTGATGCTCCGGGACACCCTCAACATTCGCCAAGCATACAA

>8972_8972_13_BAP1-PBRM1_BAP1_chr3_52438469_ENST00000460680_PBRM1_chr3_52663051_ENST00000409057_length(amino acids)=1617AA_BP=416
MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVYGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNS
CATHALLSVLLNCSSVDLGPTLSRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRL
FELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRIKYEARLHVLKVNRQTVLEALQQLIRVTQPEL
IQTHKSQESQLPEESKSASNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAF
LDNHNYAKSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNS
AIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPD
YYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGI
SPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACT
YNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRK
NVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEED
KLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKWLYGCWFYRPNETFHL
ATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRV
ASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDG
AAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRF
SLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKS
AKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGMMGGYPPGLPPLQGPVDGLVSMGSMQP
LHPGGPPPHHLPPGVPGLPGIPPPGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQ

--------------------------------------------------------------
>8972_8972_14_BAP1-PBRM1_BAP1_chr3_52438469_ENST00000460680_PBRM1_chr3_52663051_ENST00000409114_length(transcript)=5433nt_BP=1722nt
CGCTCCGCCCCTCCCCTCGCAGCACCCGGGCCTAGTACTGCCCGTCCCGCCCCTCCTCTCGAGCCTCAGCGCTCAGCATCGCCCGGACCC
CCTCTTCCCTTCGCCCGCCTCGTCCCGACCCTCCCCTTCGCCCCCGTCCCGCCCCGCCCCTCCCCTTCGCCCCCGTCCCGTCCCGCCCCG
CCCCTCCCCTTCGCCCCCGTCCCTCCCCTTCGCCCCCGTCCCTCCGCGCGTGCGCGTTCGCCTTCGAGCGCATGCCCGCATCTGCTGTCC
GACAGGCGGAAGACGAGCCCAGAGGCGGAGCAGGGCCGTCGCGCCTTGGTGACGTCTGCCGCCGGCGCGGGCGGGTGACGCGACTGGGCC
CGTTGTCTGTGTGTGGGACTGAGGGGCCCCGGGGGCGGTGGGGGCTCCCGGTGGGGGCAGCGGTGGGGAGGGAGGGCCTGGACATGGCGC
TGAGGGGCCGCCCCGCGGGAAGATGAATAAGGGCTGGCTGGAGCTGGAGAGCGACCCAGGCCTCTTCACCCTGCTCGTGGAAGATTTCGG
TGTCAAGGGGGTGCAAGTGGAGGAGATCTACGACCTTCAGAGCAAATGTCAGGGCCCTGTATATGGATTTATCTTCCTGTTCAAATGGAT
CGAAGAGCGCCGGTCCCGGCGAAAGGTCTCTACCTTGGTGGATGATACGTCCGTGATTGATGATGATATTGTGAATAACATGTTCTTTGC
CCACCAGCTGATACCCAACTCTTGTGCAACTCATGCCTTGCTGAGCGTGCTCCTGAACTGCAGCAGCGTGGACCTGGGACCCACCCTGAG
TCGCATGAAGGACTTCACCAAGGGTTTCAGCCCTGAGAGCAAAGGATATGCGATTGGCAATGCCCCGGAGTTGGCCAAGGCCCATAATAG
CCATGCCAGGCCCGAGCCACGCCACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATGGAGGCGTTCCACTTTGTCAGCTA
TGTGCCTATCACAGGCCGGCTCTTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCCTGGGGGGAGGACGAGGAGTGGAC
AGACAAGGCCCGGCGGGTCATCATGGAGCGTATCGGCCTCGCCACTGCAGGGGAGCCCTACCACGACATCCGCTTCAACCTGATGGCAGT
GGTGCCCGACCGCAGGATCAAGTATGAGGCCAGGCTGCATGTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGAT
AAGAGTAACACAGCCAGAGCTGATTCAGACCCACAAGTCTCAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCC
GCTGGTGCTGGAAGCAAACAGGGCCCCTGCAGCCTCTGAGGGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGC
CCCATCCCACAGCCCTCCCAACAAACCCAAGCTAGTGGTGAAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCAT
TGTCCAGCGGCTGCCGGCCTTTCTAGACAATCACAATTATGCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCG
CAGCCGAGTTCCAGTCCGCCCACCCCAGCAGTACTCAGATGATGAGGATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAA
CTCTGCCCTTAGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGTGATCTGAATTTAATGTTTGAAAATGCCAA
ACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAG
AGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCCAAAAGAAAAAGGAACACTCATGACAGTGA
GATGTTGGGTCTCAGGAGGCTATCCAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGA
GCCAGGTTCAGGCAGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCC
AATGGACTTGAAAATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCG
GAATGCCAGGCACTATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCT
GGGCCCACTGCCTGATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACAT
GACTCCAATGCAGCAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCT
GAGGCTTCCCTCTAGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGC
CAACAAGTACCAAGATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGAT
CTACAAAGATGCTCTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGAC
TTTGCTGATTCAAGAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGC
AGAAATTCCTGCTGTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCG
TCGGCTTGATTTATTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGC
AGTAGAACTTCAGCAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCAC
AAAACATTTGCATAATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAA
AAGAGAAGCTGAAAAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAA
CAGCATGTACCATGTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGA
GGATTCAGCTGGTGAAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAA
AGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAA
GTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACT
GTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGA
TAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCC
TGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTT
CATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCAT
CTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCC
CATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCT
GCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGA
TGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAA
ATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCT
TCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGA
AGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTC
TTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGAGCGGGCAGCTAAAGT
TGCTGAGCAGCAGGAGAGAGAGCGAGCAGCACAGCAACAGCAGCCGAGTGCTTCTCCCCGAGCAGGCACCCCTGTGGGGGCTCTCATGGG
GGTGGTGCCACCACCAACACCAATGGGGATGCTCAATCAGCAGTTGACACCTGTTGCAGGTGTGATGAACCAAGGAGTGGCCCCTATGGT
AGGGACTCCAGCACCAGGTGGAAGTCCATATGGACAACAGGTGGGAGTTTTGGGGCCTCCAGGGCAGCAGGCACCACCTCCATATCCCGG
CCCACATCCAGCTGGACCCCCTGTCATACAGCAGCCAACAACACCCATGTTTGTAGCTCCCCCACCAAAGACCCAGCGGCTTCTTCACTC
AGAGGCCTACCTGAAATACATTGAAGGACTCAGTGCGGAGTCCAACAGCATTAGCAAGTGGGATCAGACACTGGCAGCTCGAAGACGCGA
CGTCCATTTGTCGAAAGAACAGGAGAGCCGCCTACCCTCTCACTGGCTGAAAAGCAAAGGGGCCCACACCACCATGGCAGATGCCCTCTG
GCGCCTTCGAGATTTGATGCTCCGGGACACCCTCAACATTCGCCAAGCATACAACCTAGAAAATGTTTAATCACATCATTACGTTTCTTT

>8972_8972_14_BAP1-PBRM1_BAP1_chr3_52438469_ENST00000460680_PBRM1_chr3_52663051_ENST00000409114_length(amino acids)=1635AA_BP=416
MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVYGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNS
CATHALLSVLLNCSSVDLGPTLSRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRL
FELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRIKYEARLHVLKVNRQTVLEALQQLIRVTQPEL
IQTHKSQESQLPEESKSASNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAF
LDNHNYAKSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNS
AIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKRNTHDSEMLGLRRLSSKKNIRKQRMKILFNVVLEAREPGSGRRL
CDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDD
DMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDID
SMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDP
NFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHNDV
EKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKW
LYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISS
VRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLV
RPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYN
ESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASE
LDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEERAAKVAEQQERE
RAAQQQQPSASPRAGTPVGALMGVVPPPTPMGMLNQQLTPVAGVMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPP
VIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVHLSKEQESRLPSHWLKSKGAHTTMADALWRLRDLML

--------------------------------------------------------------
>8972_8972_15_BAP1-PBRM1_BAP1_chr3_52438469_ENST00000460680_PBRM1_chr3_52663051_ENST00000409767_length(transcript)=5267nt_BP=1722nt
CGCTCCGCCCCTCCCCTCGCAGCACCCGGGCCTAGTACTGCCCGTCCCGCCCCTCCTCTCGAGCCTCAGCGCTCAGCATCGCCCGGACCC
CCTCTTCCCTTCGCCCGCCTCGTCCCGACCCTCCCCTTCGCCCCCGTCCCGCCCCGCCCCTCCCCTTCGCCCCCGTCCCGTCCCGCCCCG
CCCCTCCCCTTCGCCCCCGTCCCTCCCCTTCGCCCCCGTCCCTCCGCGCGTGCGCGTTCGCCTTCGAGCGCATGCCCGCATCTGCTGTCC
GACAGGCGGAAGACGAGCCCAGAGGCGGAGCAGGGCCGTCGCGCCTTGGTGACGTCTGCCGCCGGCGCGGGCGGGTGACGCGACTGGGCC
CGTTGTCTGTGTGTGGGACTGAGGGGCCCCGGGGGCGGTGGGGGCTCCCGGTGGGGGCAGCGGTGGGGAGGGAGGGCCTGGACATGGCGC
TGAGGGGCCGCCCCGCGGGAAGATGAATAAGGGCTGGCTGGAGCTGGAGAGCGACCCAGGCCTCTTCACCCTGCTCGTGGAAGATTTCGG
TGTCAAGGGGGTGCAAGTGGAGGAGATCTACGACCTTCAGAGCAAATGTCAGGGCCCTGTATATGGATTTATCTTCCTGTTCAAATGGAT
CGAAGAGCGCCGGTCCCGGCGAAAGGTCTCTACCTTGGTGGATGATACGTCCGTGATTGATGATGATATTGTGAATAACATGTTCTTTGC
CCACCAGCTGATACCCAACTCTTGTGCAACTCATGCCTTGCTGAGCGTGCTCCTGAACTGCAGCAGCGTGGACCTGGGACCCACCCTGAG
TCGCATGAAGGACTTCACCAAGGGTTTCAGCCCTGAGAGCAAAGGATATGCGATTGGCAATGCCCCGGAGTTGGCCAAGGCCCATAATAG
CCATGCCAGGCCCGAGCCACGCCACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATGGAGGCGTTCCACTTTGTCAGCTA
TGTGCCTATCACAGGCCGGCTCTTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCCTGGGGGGAGGACGAGGAGTGGAC
AGACAAGGCCCGGCGGGTCATCATGGAGCGTATCGGCCTCGCCACTGCAGGGGAGCCCTACCACGACATCCGCTTCAACCTGATGGCAGT
GGTGCCCGACCGCAGGATCAAGTATGAGGCCAGGCTGCATGTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGAT
AAGAGTAACACAGCCAGAGCTGATTCAGACCCACAAGTCTCAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCC
GCTGGTGCTGGAAGCAAACAGGGCCCCTGCAGCCTCTGAGGGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGC
CCCATCCCACAGCCCTCCCAACAAACCCAAGCTAGTGGTGAAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCAT
TGTCCAGCGGCTGCCGGCCTTTCTAGACAATCACAATTATGCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCG
CAGCCGAGTTCCAGTCCGCCCACCCCAGCAGTACTCAGATGATGAGGATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAA
CTCTGCCCTTAGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGTGATCTGAATTTAATGTTTGAAAATGCCAA
ACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAG
AGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCCAAAAGAAAAAGGAACACTCATGACAGTGA
GATGTTGGGTCTCAGGAGGCTATCCAGTAAAAAGAACATAAGAAAGCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGA
GCCAGGTTCAGGCAGAAGACTTTGTGACCTATTTATGGTTAAACCATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCC
AATGGACTTGAAAATAATTGAGCATAACATCCGCAATGACAAATATGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCG
GAATGCCAGGCACTATAATGAGGAGGGCTCCCAGGTTTATAATGATGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCT
GGGCCCACTGCCTGATGATGATGACATGGCTTCTCCCAAACTCAAGCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACAT
GACTCCAATGCAGCAGAAACTAAATGAGGTCTATGAAGCTGTAAAGAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCT
GAGGCTTCCCTCTAGATCTGAGTTGCCTGACTACTATCTGACTATTAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGC
CAACAAGTACCAAGATATTGACTCTATGGTTGAGGACTTTGTCATGATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGAT
CTACAAAGATGCTCTTGTTCTACACAAAGTCCTGCTTGAAACACGCAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGAC
TTTGCTGATTCAAGAGCTTATCCACAATCTTTTTGTGTCAGTCATGAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGC
AGAAATTCCTGCTGTGGATCCCAACTTTCCTAACAAACCACCCCTTACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCG
TCGGCTTGATTTATTTCAAGAGCATATGTTTGAAGTATTGGAACGAGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGC
AGTAGAACTTCAGCAGTTTTTTATTAAAATTCGTGATGAACTCTGCAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCAC
AAAACATTTGCATAATGATGTGGAGAAAGAGAGAAAGGAAAAATTGCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAA
AAGAGAAGCTGAAAAGAGTGAAGATTCCTCTGGTGCTGCAGGCCTCTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAA
CAGCATGTACCATGTTGGAGATTACGTCTATGTGGAACCTGCAGAGGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGA
GGATTCAGCTGGTGAAAAATGGTTGTATGGCTGTTGGTTTTACCGACCAAATGAAACATTCCACCTGGCTACACGAAAATTTCTAGAAAA
AGAAGTTTTTAAGAGTGACTATTACAACAAAGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAA
GTTATGCCCAGAAAACTTCCGAGATGAGGATGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACT
GTGGACCATGCCCATCAGCTCAGTCAGGTTTGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGA
TAAAGGTGATGATGAGAAGAATACAGACAACTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCC
TGTGGAAATGTCCAATGGTGAACCAGGTTGCCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTT
CATCAAGTCCCATGGCCTGGTGCGTCCTCGTGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCAT
CTTCATTCACCCAGAAGAAACAGAGCATGAGCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCC
CATGACATGTATTCTCGGAAAGTGTGCTGTGTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCT
GCTTTGTGAGAGCCGCTACAATGAGAGCGACAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGA
TGATGAAATTTACTACTTCAGAAAACCAATTGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAA
ATTTGCCGAGTTAGAAGGTGGAGATGATGATATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCT
TCAGACCCCCCTGGCCAGTGAGCTGGACCTCATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGA
AGGCTCCAAACGGAAAATCAACATGAGTGGCTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTC
TTTCGGGGAGCTCAGCCGCCTGGTGGGGACAGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGGTGTGATGAACCAAGG
AGTGGCCCCTATGGTAGGGACTCCAGCACCAGGTGGAAGTCCATATGGACAACAGGTGGGAGTTTTGGGGCCTCCAGGGCAGCAGGCACC
ACCTCCATATCCCGGCCCACATCCAGCTGGACCCCCTGTCATACAGCAGCCAACAACACCCATGTTTGTAGCTCCCCCACCAAAGACCCA
GCGGCTTCTTCACTCAGAGGCCTACCTGAAATACATTGAAGGACTCAGTGCGGAGTCCAACAGCATTAGCAAGTGGGATCAGACACTGGC
AGCTCGAAGACGCGACGTCCATTTGTCGAAAGAACAGGAGAGCCGCCTACCCTCTCACTGGCTGAAAAGCAAAGGGGCCCACACCACCAT
GGCAGATGCCCTCTGGCGCCTTCGAGATTTGATGCTCCGGGACACCCTCAACATTCGCCAAGCATACAACCTAGAAAATGTTTAATCACA

>8972_8972_15_BAP1-PBRM1_BAP1_chr3_52438469_ENST00000460680_PBRM1_chr3_52663051_ENST00000409767_length(amino acids)=1580AA_BP=416
MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVYGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNS
CATHALLSVLLNCSSVDLGPTLSRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRL
FELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRIKYEARLHVLKVNRQTVLEALQQLIRVTQPEL
IQTHKSQESQLPEESKSASNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAF
LDNHNYAKSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNS
AIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKRNTHDSEMLGLRRLSSKKNIRKQRMKILFNVVLEAREPGSGRRL
CDLFMVKPSKKDYPDYYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDD
DMASPKLKLSRKSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDID
SMVEDFVMMFNNACTYNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDP
NFPNKPPLTFDIIRKNVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHNDV
EKERKEKLPKEIEEDKLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAGEKW
LYGCWFYRPNETFHLATRKFLEKEVFKSDYYNKVPVSKILGKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISS
VRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAEDNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLV
RPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYKKEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYN
ESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPSPLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASE
LDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSEMRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGVMNQGVAPMVGT
PAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKWDQTLAARRRDVH

--------------------------------------------------------------
>8972_8972_16_BAP1-PBRM1_BAP1_chr3_52438469_ENST00000460680_PBRM1_chr3_52663051_ENST00000410007_length(transcript)=5323nt_BP=1722nt
CGCTCCGCCCCTCCCCTCGCAGCACCCGGGCCTAGTACTGCCCGTCCCGCCCCTCCTCTCGAGCCTCAGCGCTCAGCATCGCCCGGACCC
CCTCTTCCCTTCGCCCGCCTCGTCCCGACCCTCCCCTTCGCCCCCGTCCCGCCCCGCCCCTCCCCTTCGCCCCCGTCCCGTCCCGCCCCG
CCCCTCCCCTTCGCCCCCGTCCCTCCCCTTCGCCCCCGTCCCTCCGCGCGTGCGCGTTCGCCTTCGAGCGCATGCCCGCATCTGCTGTCC
GACAGGCGGAAGACGAGCCCAGAGGCGGAGCAGGGCCGTCGCGCCTTGGTGACGTCTGCCGCCGGCGCGGGCGGGTGACGCGACTGGGCC
CGTTGTCTGTGTGTGGGACTGAGGGGCCCCGGGGGCGGTGGGGGCTCCCGGTGGGGGCAGCGGTGGGGAGGGAGGGCCTGGACATGGCGC
TGAGGGGCCGCCCCGCGGGAAGATGAATAAGGGCTGGCTGGAGCTGGAGAGCGACCCAGGCCTCTTCACCCTGCTCGTGGAAGATTTCGG
TGTCAAGGGGGTGCAAGTGGAGGAGATCTACGACCTTCAGAGCAAATGTCAGGGCCCTGTATATGGATTTATCTTCCTGTTCAAATGGAT
CGAAGAGCGCCGGTCCCGGCGAAAGGTCTCTACCTTGGTGGATGATACGTCCGTGATTGATGATGATATTGTGAATAACATGTTCTTTGC
CCACCAGCTGATACCCAACTCTTGTGCAACTCATGCCTTGCTGAGCGTGCTCCTGAACTGCAGCAGCGTGGACCTGGGACCCACCCTGAG
TCGCATGAAGGACTTCACCAAGGGTTTCAGCCCTGAGAGCAAAGGATATGCGATTGGCAATGCCCCGGAGTTGGCCAAGGCCCATAATAG
CCATGCCAGGCCCGAGCCACGCCACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATGGAGGCGTTCCACTTTGTCAGCTA
TGTGCCTATCACAGGCCGGCTCTTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCCTGGGGGGAGGACGAGGAGTGGAC
AGACAAGGCCCGGCGGGTCATCATGGAGCGTATCGGCCTCGCCACTGCAGGGGAGCCCTACCACGACATCCGCTTCAACCTGATGGCAGT
GGTGCCCGACCGCAGGATCAAGTATGAGGCCAGGCTGCATGTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGAT
AAGAGTAACACAGCCAGAGCTGATTCAGACCCACAAGTCTCAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCC
GCTGGTGCTGGAAGCAAACAGGGCCCCTGCAGCCTCTGAGGGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGC
CCCATCCCACAGCCCTCCCAACAAACCCAAGCTAGTGGTGAAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCAT
TGTCCAGCGGCTGCCGGCCTTTCTAGACAATCACAATTATGCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCG
CAGCCGAGTTCCAGTCCGCCCACCCCAGCAGTACTCAGATGATGAGGATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAA
CTCTGCCCTTAGAACAAAACTGAAGAATCAAGAATATGAAACTTTAGATCATTTGGAGTGTGATCTGAATTTAATGTTTGAAAATGCCAA
ACGCTATAATGTGCCCAATTCAGCCATCTACAAGCGAGTTCTAAAATTGCAGCAAGTTATGCAGGCAAAGAAGAAAGAGCTTGCCAGGAG
AGACGATATCGAGGACGGAGACAGCATGATCTCTTCAGCCACCTCTGATACTGGTAGTGCCAAAAGAAAAAGTAAAAAGAACATAAGAAA
GCAGCGAATGAAAATCTTATTCAATGTTGTTCTTGAAGCTCGAGAGCCAGGTTCAGGCAGAAGACTTTGTGACCTATTTATGGTTAAACC
ATCCAAAAAGGACTATCCTGATTATTATAAAATCATCTTGGAGCCAATGGACTTGAAAATAATTGAGCATAACATCCGCAATGACAAATA
TGCTGGTGAAGAGGGAATGATAGAAGACATGAAGCTGATGTTCCGGAATGCCAGGCACTATAATGAGGAGGGCTCCCAGGTTTATAATGA
TGCACATATCCTGGAGAAGTTACTCAAGGAGAAAAGGAAAGAGCTGGGCCCACTGCCTGATGATGATGACATGGCTTCTCCCAAACTCAA
GCTGAGTAGGAAGAGTGGCATTTCTCCTAAAAAATCAAAATACATGACTCCAATGCAGCAGAAACTAAATGAGGTCTATGAAGCTGTAAA
GAACTATACTGATAAGAGGGGTCGCCGCCTCAGTGCCATATTTCTGAGGCTTCCCTCTAGATCTGAGTTGCCTGACTACTATCTGACTAT
TAAAAAGCCCATGGACATGGAAAAAATTCGAAGTCACATGATGGCCAACAAGTACCAAGATATTGACTCTATGGTTGAGGACTTTGTCAT
GATGTTTAATAATGCCTGTACATACAATGAGCCGGAGTCTTTGATCTACAAAGATGCTCTTGTTCTACACAAAGTCCTGCTTGAAACACG
CAGAGACCTGGAGGGAGATGAGGACTCTCATGTCCCAAATGTGACTTTGCTGATTCAAGAGCTTATCCACAATCTTTTTGTGTCAGTCAT
GAGTCATCAGGATGATGAGGGAAGATGCTACAGCGATTCTTTAGCAGAAATTCCTGCTGTGGATCCCAACTTTCCTAACAAACCACCCCT
TACATTTGACATAATTAGGAAGAATGTTGAAAATAATCGCTACCGTCGGCTTGATTTATTTCAAGAGCATATGTTTGAAGTATTGGAACG
AGCAAGAAGGATGAATCGGACAGATTCAGAAATATATGAAGATGCAGTAGAACTTCAGCAGTTTTTTATTAAAATTCGTGATGAACTCTG
CAAAAATGGAGAGATTCTTCTTTCACCGGCACTCAGCTATACCACAAAACATTTGCATAATGATGTGGAGAAAGAGAGAAAGGAAAAATT
GCCAAAAGAAATAGAGGAAGATAAACTAAAACGAGAAGAAGAAAAAAGAGAAGCTGAAAAGAGTGAAGATTCCTCTGGTGCTGCAGGCCT
CTCAGGCTTACATCGCACATACAGCCAGGACTGTAGCTTTAAAAACAGCATGTACCATGTTGGAGATTACGTCTATGTGGAACCTGCAGA
GGCCAACCTACAACCACATATCGTCTGTATTGAAAGACTGTGGGAGGATTCAGCTGAAAAAGAAGTTTTTAAGAGTGACTATTACAACAA
AGTTCCAGTTAGTAAAATTCTAGGCAAGTGTGTGGTCATGTTTGTCAAGGAATACTTTAAGTTATGCCCAGAAAACTTCCGAGATGAGGA
TGTTTTTGTCTGTGAATCACGGTATTCTGCCAAAACCAAATCTTTTAAGAAAATTAAACTGTGGACCATGCCCATCAGCTCAGTCAGGTT
TGTCCCTCGGGATGTGCCTCTGCCTGTGGTTCGCGTGGCCTCTGTATTTGCAAATGCAGATAAAGGTGATGATGAGAAGAATACAGACAA
CTCAGAGGACAGTCGAGCTGAAGACAATTTTAACTTGGAAAAGGAAAAAGAAGATGTCCCTGTGGAAATGTCCAATGGTGAACCAGGTTG
CCACTACTTTGAGCAGCTCCATTACAATGACATGTGGCTGAAGGTTGGCGACTGTGTCTTCATCAAGTCCCATGGCCTGGTGCGTCCTCG
TGTGGGCAGAATTGAAAAAGTATGGGTTCGAGATGGAGCTGCATATTTTTATGGCCCCATCTTCATTCACCCAGAAGAAACAGAGCATGA
GCCCACAAAAATGTTCTACAAAAAAGAAGTATTTCTGAGTAATCTGGAAGAAACCTGCCCCATGACATGTATTCTCGGAAAGTGTGCTGT
GTTGTCATTCAAGGACTTCCTCTCCTGCAGGCCAACTGAAATACCAGAAAATGACATTCTGCTTTGTGAGAGCCGCTACAATGAGAGCGA
CAAGCAGATGAAGAAATTCAAAGGATTGAAGAGGTTTTCACTCTCTGCTAAAGTGGTAGATGATGAAATTTACTACTTCAGAAAACCAAT
TGTTCCTCAGAAGGAGCCATCACCTTTGCTGGAAAAGAAGATCCAGTTGCTAGAAGCTAAATTTGCCGAGTTAGAAGGTGGAGATGATGA
TATTGAAGAGATGGGAGAAGAAGATAGTGAGGTCATTGAACCTCCTTCTCTACCTCAGCTTCAGACCCCCCTGGCCAGTGAGCTGGACCT
CATGCCCTACACACCCCCACAGTCTACCCCAAAGTCTGCCAAAGGCAGTGCAAAGAAGGAAGGCTCCAAACGGAAAATCAACATGAGTGG
CTACATCCTGTTCAGCAGTGAGATGAGGGCTGTGATTAAGGCCCAACACCCAGACTACTCTTTCGGGGAGCTCAGCCGCCTGGTGGGGAC
AGAATGGAGAAATCTTGAGACAGCCAAGAAAGCAGAATATGAAGGCATGATGGGTGGCTATCCGCCAGGCCTTCCACCTTTGCAGGGCCC
AGTTGATGGCCTTGTTAGCATGGGCAGCATGCAGCCACTTCACCCTGGGGGGCCTCCACCCCACCATCTTCCGCCAGGTGTGCCTGGCCT
CCCGGGCATCCCACCACCGGGTGTGATGAACCAAGGAGTGGCCCCTATGGTAGGGACTCCAGCACCAGGTGGAAGTCCATATGGACAACA
GGTGGGAGTTTTGGGGCCTCCAGGGCAGCAGGCACCACCTCCATATCCCGGCCCACATCCAGCTGGACCCCCTGTCATACAGCAGCCAAC
AACACCCATGTTTGTAGCTCCCCCACCAAAGACCCAGCGGCTTCTTCACTCAGAGGCCTACCTGAAATACATTGAAGGACTCAGTGCGGA
GTCCAACAGCATTAGCAAGTGGGATCAGACACTGGCAGCTCGAAGACGCGACGTCCATTTGTCGAAAGAACAGGAGAGCCGCCTACCCTC
TCACTGGCTGAAAAGCAAAGGGGCCCACACCACCATGGCAGATGCCCTCTGGCGCCTTCGAGATTTGATGCTCCGGGACACCCTCAACAT
TCGCCAAGCATACAACCTAGAAAATGTTTAATCACATCATTACGTTTCTTTTATATAGAAGCATAAAGAGTTGTGGATCAGTAGCCATTT

>8972_8972_16_BAP1-PBRM1_BAP1_chr3_52438469_ENST00000460680_PBRM1_chr3_52663051_ENST00000410007_length(amino acids)=1592AA_BP=416
MNKGWLELESDPGLFTLLVEDFGVKGVQVEEIYDLQSKCQGPVYGFIFLFKWIEERRSRRKVSTLVDDTSVIDDDIVNNMFFAHQLIPNS
CATHALLSVLLNCSSVDLGPTLSRMKDFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRL
FELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRIKYEARLHVLKVNRQTVLEALQQLIRVTQPEL
IQTHKSQESQLPEESKSASNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAF
LDNHNYAKSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRTKLKNQEYETLDHLECDLNLMFENAKRYNVPNS
AIYKRVLKLQQVMQAKKKELARRDDIEDGDSMISSATSDTGSAKRKSKKNIRKQRMKILFNVVLEAREPGSGRRLCDLFMVKPSKKDYPD
YYKIILEPMDLKIIEHNIRNDKYAGEEGMIEDMKLMFRNARHYNEEGSQVYNDAHILEKLLKEKRKELGPLPDDDDMASPKLKLSRKSGI
SPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAIFLRLPSRSELPDYYLTIKKPMDMEKIRSHMMANKYQDIDSMVEDFVMMFNNACT
YNEPESLIYKDALVLHKVLLETRRDLEGDEDSHVPNVTLLIQELIHNLFVSVMSHQDDEGRCYSDSLAEIPAVDPNFPNKPPLTFDIIRK
NVENNRYRRLDLFQEHMFEVLERARRMNRTDSEIYEDAVELQQFFIKIRDELCKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEED
KLKREEEKREAEKSEDSSGAAGLSGLHRTYSQDCSFKNSMYHVGDYVYVEPAEANLQPHIVCIERLWEDSAEKEVFKSDYYNKVPVSKIL
GKCVVMFVKEYFKLCPENFRDEDVFVCESRYSAKTKSFKKIKLWTMPISSVRFVPRDVPLPVVRVASVFANADKGDDEKNTDNSEDSRAE
DNFNLEKEKEDVPVEMSNGEPGCHYFEQLHYNDMWLKVGDCVFIKSHGLVRPRVGRIEKVWVRDGAAYFYGPIFIHPEETEHEPTKMFYK
KEVFLSNLEETCPMTCILGKCAVLSFKDFLSCRPTEIPENDILLCESRYNESDKQMKKFKGLKRFSLSAKVVDDEIYYFRKPIVPQKEPS
PLLEKKIQLLEAKFAELEGGDDDIEEMGEEDSEVIEPPSLPQLQTPLASELDLMPYTPPQSTPKSAKGSAKKEGSKRKINMSGYILFSSE
MRAVIKAQHPDYSFGELSRLVGTEWRNLETAKKAEYEGMMGGYPPGLPPLQGPVDGLVSMGSMQPLHPGGPPPHHLPPGVPGLPGIPPPG
VMNQGVAPMVGTPAPGGSPYGQQVGVLGPPGQQAPPPYPGPHPAGPPVIQQPTTPMFVAPPPKTQRLLHSEAYLKYIEGLSAESNSISKW

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Fusion Gene PPI Analysis for BAP1-PBRM1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneBAP1chr3:52438469chr3:52663051ENST00000460680-1217596_721416.6666666666667730.0BRCA1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for BAP1-PBRM1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for BAP1-PBRM1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneBAP1C3280492TUMOR PREDISPOSITION SYNDROME7CLINGEN;CTD_human;GENOMICS_ENGLAND;ORPHANET
HgeneBAP1C0220633Uveal melanoma5CGI;CTD_human;GENOMICS_ENGLAND;ORPHANET
HgeneBAP1C0345967Malignant mesothelioma5CTD_human
HgeneBAP1C0007134Renal Cell Carcinoma4CTD_human
HgeneBAP1C0025500Mesothelioma4CGI;CTD_human
HgeneBAP1C0279702Conventional (Clear Cell) Renal Cell Carcinoma4CGI;CTD_human
HgeneBAP1C1266042Chromophobe Renal Cell Carcinoma4CTD_human
HgeneBAP1C1266043Sarcomatoid Renal Cell Carcinoma4CTD_human
HgeneBAP1C1266044Collecting Duct Carcinoma of the Kidney4CTD_human
HgeneBAP1C1306837Papillary Renal Cell Carcinoma4CTD_human
HgeneBAP1C0006142Malignant neoplasm of breast2CGI;CTD_human
HgeneBAP1C0024623Malignant neoplasm of stomach2CTD_human
HgeneBAP1C0038356Stomach Neoplasms2CTD_human
HgeneBAP1C0151779Cutaneous Melanoma2CGI;CTD_human;GENOMICS_ENGLAND
HgeneBAP1C0206698Cholangiocarcinoma2CTD_human
HgeneBAP1C0345905Intrahepatic Cholangiocarcinoma2CTD_human
HgeneBAP1C0346373Malignant melanoma of iris2ORPHANET
HgeneBAP1C0346388Malignant melanoma of choroid2ORPHANET
HgeneBAP1C0678222Breast Carcinoma2CGI;CTD_human
HgeneBAP1C1257931Mammary Neoplasms, Human2CTD_human
HgeneBAP1C1458155Mammary Neoplasms2CTD_human
HgeneBAP1C1708349Hereditary Diffuse Gastric Cancer2CTD_human
HgeneBAP1C3805278Extrahepatic Cholangiocarcinoma2CTD_human
HgeneBAP1C4704874Mammary Carcinoma, Human2CTD_human
HgeneBAP1C0005684Malignant neoplasm of urinary bladder1CTD_human
HgeneBAP1C0005695Bladder Neoplasm1CTD_human
HgeneBAP1C0005967Bone neoplasms1CTD_human
HgeneBAP1C0007102Malignant tumor of colon1CTD_human
HgeneBAP1C0009375Colonic Neoplasms1CTD_human
HgeneBAP1C0018671Head and Neck Neoplasms1CTD_human
HgeneBAP1C0018675Head Neoplasms1CTD_human
HgeneBAP1C0022665Kidney Neoplasm1CGI;CTD_human
HgeneBAP1C0023418leukemia1CTD_human
HgeneBAP1C0023798Lipoma1CTD_human
HgeneBAP1C0023903Liver neoplasms1CTD_human
HgeneBAP1C0024121Lung Neoplasms1CTD_human
HgeneBAP1C0025286Meningioma1CTD_human;GENOMICS_ENGLAND
HgeneBAP1C0027533Neck Neoplasms1CTD_human
HgeneBAP1C0030297Pancreatic Neoplasm1CTD_human
HgeneBAP1C0030421Paraganglioma1CTD_human
HgeneBAP1C0033578Prostatic Neoplasms1CTD_human
HgeneBAP1C0039590Testicular Neoplasms1CTD_human
HgeneBAP1C0040100Thymoma1CTD_human
HgeneBAP1C0042138Uterine Neoplasms1CTD_human
HgeneBAP1C0085136Central Nervous System Neoplasms1CTD_human
HgeneBAP1C0152013Adenocarcinoma of lung (disorder)1CTD_human
HgeneBAP1C0153567Uterine Cancer1CTD_human
HgeneBAP1C0153594Malignant neoplasm of testis1CTD_human
HgeneBAP1C0205822Hibernoma1CTD_human
HgeneBAP1C0205823Pleomorphic Lipoma1CTD_human
HgeneBAP1C0205834Meningiomas, Multiple1CTD_human
HgeneBAP1C0205969Thymic Carcinoma1CTD_human
HgeneBAP1C0206686Adrenocortical carcinoma1CTD_human
HgeneBAP1C0206694Mucoepidermoid Carcinoma1CTD_human
HgeneBAP1C0206739Epithelioid and spindle cell nevus1CTD_human
HgeneBAP1C0206754Neuroendocrine Tumors1CTD_human
HgeneBAP1C0206769Nevi and Melanomas1CTD_human
HgeneBAP1C0242379Malignant neoplasm of lung1CTD_human;UNIPROT
HgeneBAP1C0259785Malignant Meningioma1CTD_human
HgeneBAP1C0278996Malignant Head and Neck Neoplasm1CTD_human
HgeneBAP1C0279530Malignant Bone Neoplasm1CTD_human
HgeneBAP1C0281784Benign Meningioma1CTD_human
HgeneBAP1C0334605Meningothelial meningioma1CTD_human
HgeneBAP1C0334606Fibrous Meningioma1CTD_human
HgeneBAP1C0334607Psammomatous Meningioma1CTD_human
HgeneBAP1C0334608Angiomatous Meningioma1CTD_human
HgeneBAP1C0334609Hemangioblastic Meningioma1CTD_human
HgeneBAP1C0334610Hemangiopericytic Meningioma1CTD_human
HgeneBAP1C0334611Transitional Meningioma1CTD_human
HgeneBAP1C0345904Malignant neoplasm of liver1CTD_human
HgeneBAP1C0346647Malignant neoplasm of pancreas1CTD_human
HgeneBAP1C0347515Spinal Meningioma1CTD_human
HgeneBAP1C0349604Intracranial Meningioma1CTD_human
HgeneBAP1C0376358Malignant neoplasm of prostate1CTD_human
HgeneBAP1C0431121Clear Cell Meningioma1CTD_human
HgeneBAP1C0457190Xanthomatous Meningioma1CTD_human
HgeneBAP1C0740457Malignant neoplasm of kidney1CGI;CTD_human
HgeneBAP1C0746787Cancer of Neck1CTD_human
HgeneBAP1C0751177Cancer of Head1CTD_human
HgeneBAP1C0751303Cerebral Convexity Meningioma1CTD_human
HgeneBAP1C0751304Parasagittal Meningioma1CTD_human
HgeneBAP1C0751620Central Nervous System Neoplasms, Primary1CTD_human
HgeneBAP1C0887900Upper Aerodigestive Tract Neoplasms1CTD_human
HgeneBAP1C0919267ovarian neoplasm1CTD_human
HgeneBAP1C1140680Malignant neoplasm of ovary1CTD_human
HgeneBAP1C1334261Intraorbital Meningioma1CTD_human
HgeneBAP1C1334271Intraventricular Meningioma1CTD_human
HgeneBAP1C1335107Olfactory Groove Meningioma1CTD_human
HgeneBAP1C1368275Pigmented Basal Cell Carcinoma1CTD_human
HgeneBAP1C1384406Secretory meningioma1CTD_human
HgeneBAP1C1384408Microcystic meningioma1CTD_human
HgeneBAP1C1527197Angioblastic Meningioma1CTD_human
HgeneBAP1C1565950Posterior Fossa Meningioma1CTD_human
HgeneBAP1C1565951Sphenoid Wing Meningioma1CTD_human
HgeneBAP1C1708353Hereditary Paraganglioma-Pheochromocytoma Syndrome1CLINGEN
HgeneBAP1C1720811Tumor of Rete Testis1CTD_human
HgeneBAP1C2314896Familial Atypical Mole Melanoma Syndrome1ORPHANET
HgeneBAP1C2931822Nasopharyngeal carcinoma1CTD_human
HgeneBAP1C3163622Papillary Meningioma1CTD_human
HgeneBAP1C3489413Lipomatosis, Multiple1CTD_human
HgeneBAP1C4721806Carcinoma, Basal Cell1CTD_human
TgeneC0005586Bipolar Disorder3PSYGENET
TgeneC0007134Renal Cell Carcinoma2CTD_human
TgeneC0279702Conventional (Clear Cell) Renal Cell Carcinoma2CGI;CTD_human
TgeneC1266042Chromophobe Renal Cell Carcinoma2CTD_human
TgeneC1266043Sarcomatoid Renal Cell Carcinoma2CTD_human
TgeneC1266044Collecting Duct Carcinoma of the Kidney2CTD_human
TgeneC1306837Papillary Renal Cell Carcinoma2CTD_human
TgeneC0033975Psychotic Disorders1PSYGENET
TgeneC0036341Schizophrenia1PSYGENET
TgeneC0040100Thymoma1CTD_human
TgeneC0205969Thymic Carcinoma1CTD_human
TgeneC0206698Cholangiocarcinoma1CTD_human
TgeneC0345905Intrahepatic Cholangiocarcinoma1CTD_human
TgeneC0349204Nonorganic psychosis1PSYGENET
TgeneC3805278Extrahepatic Cholangiocarcinoma1CTD_human
TgeneC4518333Clear cell papillary renal cell carcinoma1ORPHANET