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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Diseases

Fusion gene:FCRL5-PHF11 (FusionGDB2 ID:HG83416TG51131)

Fusion Gene Summary for FCRL5-PHF11

check button Fusion gene summary
Fusion gene informationFusion gene name: FCRL5-PHF11
Fusion gene ID: hg83416tg51131
HgeneTgene
Gene symbol

FCRL5

PHF11

Gene ID

83416

51131

Gene nameFc receptor like 5PHD finger protein 11
SynonymsBXMAS1|CD307|CD307e|FCRH5|IRTA2|PRO820APY|BCAP|IGEL|IGER|IGHER|NY-REN-34|NYREN34
Cytomap('FCRL5')('PHF11')

1q23.1

13q14.2

Type of geneprotein-codingprotein-coding
DescriptionFc receptor-like protein 5fc receptor homolog 5fcR-like protein 5immune receptor translocation-associated protein 2immunoglobulin superfamily receptor translocation associated 2 (IRTA2)PHD finger protein 11BRCA1 C-terminus-associated proteinIgE responsiveness (atopic)renal carcinoma antigen NY-REN-34
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000356953, ENST00000361835, 
ENST00000368190, ENST00000368191, 
ENST00000368188, ENST00000368189, 
ENST00000461387, 
Fusion gene scores* DoF score2 X 2 X 2=84 X 5 X 3=60
# samples 28
** MAII scorelog2(2/8*10)=1.32192809488736log2(8/60*10)=0.415037499278844
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: FCRL5 [Title/Abstract] AND PHF11 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointFCRL5(157504404)-PHF11(50080771), # samples:1
Anticipated loss of major functional domain due to fusion event.FCRL5-PHF11 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
FCRL5-PHF11 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
FCRL5-PHF11 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
FCRL5-PHF11 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across FCRL5 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across PHF11 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-HU-A4GT-01AFCRL5chr1

157504404

-PHF11chr13

50080771

+


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Fusion Gene ORF analysis for FCRL5-PHF11

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000356953ENST00000357596FCRL5chr1

157504404

-PHF11chr13

50080771

+
5CDS-5UTRENST00000356953ENST00000488958FCRL5chr1

157504404

-PHF11chr13

50080771

+
5CDS-5UTRENST00000361835ENST00000357596FCRL5chr1

157504404

-PHF11chr13

50080771

+
5CDS-5UTRENST00000361835ENST00000488958FCRL5chr1

157504404

-PHF11chr13

50080771

+
5CDS-5UTRENST00000368190ENST00000357596FCRL5chr1

157504404

-PHF11chr13

50080771

+
5CDS-5UTRENST00000368190ENST00000488958FCRL5chr1

157504404

-PHF11chr13

50080771

+
5CDS-5UTRENST00000368191ENST00000357596FCRL5chr1

157504404

-PHF11chr13

50080771

+
5CDS-5UTRENST00000368191ENST00000488958FCRL5chr1

157504404

-PHF11chr13

50080771

+
5CDS-intronENST00000356953ENST00000460489FCRL5chr1

157504404

-PHF11chr13

50080771

+
5CDS-intronENST00000361835ENST00000460489FCRL5chr1

157504404

-PHF11chr13

50080771

+
5CDS-intronENST00000368190ENST00000460489FCRL5chr1

157504404

-PHF11chr13

50080771

+
5CDS-intronENST00000368191ENST00000460489FCRL5chr1

157504404

-PHF11chr13

50080771

+
In-frameENST00000356953ENST00000378319FCRL5chr1

157504404

-PHF11chr13

50080771

+
In-frameENST00000361835ENST00000378319FCRL5chr1

157504404

-PHF11chr13

50080771

+
In-frameENST00000368190ENST00000378319FCRL5chr1

157504404

-PHF11chr13

50080771

+
In-frameENST00000368191ENST00000378319FCRL5chr1

157504404

-PHF11chr13

50080771

+
intron-3CDSENST00000368188ENST00000378319FCRL5chr1

157504404

-PHF11chr13

50080771

+
intron-3CDSENST00000368189ENST00000378319FCRL5chr1

157504404

-PHF11chr13

50080771

+
intron-3CDSENST00000461387ENST00000378319FCRL5chr1

157504404

-PHF11chr13

50080771

+
intron-5UTRENST00000368188ENST00000357596FCRL5chr1

157504404

-PHF11chr13

50080771

+
intron-5UTRENST00000368188ENST00000488958FCRL5chr1

157504404

-PHF11chr13

50080771

+
intron-5UTRENST00000368189ENST00000357596FCRL5chr1

157504404

-PHF11chr13

50080771

+
intron-5UTRENST00000368189ENST00000488958FCRL5chr1

157504404

-PHF11chr13

50080771

+
intron-5UTRENST00000461387ENST00000357596FCRL5chr1

157504404

-PHF11chr13

50080771

+
intron-5UTRENST00000461387ENST00000488958FCRL5chr1

157504404

-PHF11chr13

50080771

+
intron-intronENST00000368188ENST00000460489FCRL5chr1

157504404

-PHF11chr13

50080771

+
intron-intronENST00000368189ENST00000460489FCRL5chr1

157504404

-PHF11chr13

50080771

+
intron-intronENST00000461387ENST00000460489FCRL5chr1

157504404

-PHF11chr13

50080771

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000361835FCRL5chr1157504404-ENST00000378319PHF11chr1350080771+306318391402740866
ENST00000356953FCRL5chr1157504404-ENST00000378319PHF11chr1350080771+29331709102610866
ENST00000368190FCRL5chr1157504404-ENST00000378319PHF11chr1350080771+29981774752675866
ENST00000368191FCRL5chr1157504404-ENST00000378319PHF11chr1350080771+278115571132458781

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000361835ENST00000378319FCRL5chr1157504404-PHF11chr1350080771+0.0001670750.99983287
ENST00000356953ENST00000378319FCRL5chr1157504404-PHF11chr1350080771+0.0002005760.99979943
ENST00000368190ENST00000378319FCRL5chr1157504404-PHF11chr1350080771+0.0001620890.9998379
ENST00000368191ENST00000378319FCRL5chr1157504404-PHF11chr1350080771+0.0004684550.9995315

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Fusion Genomic Features for FCRL5-PHF11


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
FCRL5chr1157504403-PHF11chr1350080770+6.72E-050.9999329
FCRL5chr1157504403-PHF11chr1350080770+6.72E-050.9999329

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for FCRL5-PHF11


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:157504404/chr13:50080771)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFCRL5chr1:157504404chr13:50080771ENST00000361835-817188_271560978.0DomainNote=Ig-like C2-type 2
HgeneFCRL5chr1:157504404chr13:50080771ENST00000361835-81723_101560978.0DomainNote=Ig-like C2-type 1
HgeneFCRL5chr1:157504404chr13:50080771ENST00000361835-817287_374560978.0DomainNote=Ig-like C2-type 3
HgeneFCRL5chr1:157504404chr13:50080771ENST00000361835-817380_463560978.0DomainNote=Ig-like C2-type 4
HgeneFCRL5chr1:157504404chr13:50080771ENST00000361835-817473_556560978.0DomainNote=Ig-like C2-type 5
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368190-810188_271560760.0DomainNote=Ig-like C2-type 2
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368190-81023_101560760.0DomainNote=Ig-like C2-type 1
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368190-810287_374560760.0DomainNote=Ig-like C2-type 3
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368190-810380_463560760.0DomainNote=Ig-like C2-type 4
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368190-810473_556560760.0DomainNote=Ig-like C2-type 5
TgenePHF11chr1:157504404chr13:50080771ENST00000357596111108_1600293.0Zinc fingerPHD-type
TgenePHF11chr1:157504404chr13:50080771ENST0000035759611142_780293.0Zinc fingerC2HC pre-PHD-type
TgenePHF11chr1:157504404chr13:50080771ENST00000378319010108_16031332.0Zinc fingerPHD-type
TgenePHF11chr1:157504404chr13:50080771ENST0000037831901042_7831332.0Zinc fingerC2HC pre-PHD-type
TgenePHF11chr1:157504404chr13:50080771ENST00000488958010108_1600293.0Zinc fingerPHD-type
TgenePHF11chr1:157504404chr13:50080771ENST0000048895801042_780293.0Zinc fingerC2HC pre-PHD-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneFCRL5chr1:157504404chr13:50080771ENST00000361835-817566_651560978.0DomainNote=Ig-like C2-type 6
HgeneFCRL5chr1:157504404chr13:50080771ENST00000361835-817659_744560978.0DomainNote=Ig-like C2-type 7
HgeneFCRL5chr1:157504404chr13:50080771ENST00000361835-817752_834560978.0DomainNote=Ig-like C2-type 8
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368188-14188_2710125.0DomainNote=Ig-like C2-type 2
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368188-1423_1010125.0DomainNote=Ig-like C2-type 1
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368188-14287_3740125.0DomainNote=Ig-like C2-type 3
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368188-14380_4630125.0DomainNote=Ig-like C2-type 4
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368188-14473_5560125.0DomainNote=Ig-like C2-type 5
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368188-14566_6510125.0DomainNote=Ig-like C2-type 6
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368188-14659_7440125.0DomainNote=Ig-like C2-type 7
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368188-14752_8340125.0DomainNote=Ig-like C2-type 8
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368189-18188_2710593.0DomainNote=Ig-like C2-type 2
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368189-1823_1010593.0DomainNote=Ig-like C2-type 1
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368189-18287_3740593.0DomainNote=Ig-like C2-type 3
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368189-18380_4630593.0DomainNote=Ig-like C2-type 4
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368189-18473_5560593.0DomainNote=Ig-like C2-type 5
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368189-18566_6510593.0DomainNote=Ig-like C2-type 6
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368189-18659_7440593.0DomainNote=Ig-like C2-type 7
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368189-18752_8340593.0DomainNote=Ig-like C2-type 8
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368190-810566_651560760.0DomainNote=Ig-like C2-type 6
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368190-810659_744560760.0DomainNote=Ig-like C2-type 7
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368190-810752_834560760.0DomainNote=Ig-like C2-type 8
HgeneFCRL5chr1:157504404chr13:50080771ENST00000361835-817897_902560978.0MotifNote=ITIM motif 1
HgeneFCRL5chr1:157504404chr13:50080771ENST00000361835-817910_915560978.0MotifNote=ITIM motif 2
HgeneFCRL5chr1:157504404chr13:50080771ENST00000361835-817922_927560978.0MotifNote=ITIM motif 3
HgeneFCRL5chr1:157504404chr13:50080771ENST00000361835-817952_957560978.0MotifNote=ITIM motif 4
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368188-14897_9020125.0MotifNote=ITIM motif 1
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368188-14910_9150125.0MotifNote=ITIM motif 2
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368188-14922_9270125.0MotifNote=ITIM motif 3
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368188-14952_9570125.0MotifNote=ITIM motif 4
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368189-18897_9020593.0MotifNote=ITIM motif 1
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368189-18910_9150593.0MotifNote=ITIM motif 2
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368189-18922_9270593.0MotifNote=ITIM motif 3
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368189-18952_9570593.0MotifNote=ITIM motif 4
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368190-810897_902560760.0MotifNote=ITIM motif 1
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368190-810910_915560760.0MotifNote=ITIM motif 2
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368190-810922_927560760.0MotifNote=ITIM motif 3
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368190-810952_957560760.0MotifNote=ITIM motif 4
HgeneFCRL5chr1:157504404chr13:50080771ENST00000361835-81716_851560978.0Topological domainExtracellular
HgeneFCRL5chr1:157504404chr13:50080771ENST00000361835-817873_977560978.0Topological domainCytoplasmic
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368188-1416_8510125.0Topological domainExtracellular
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368188-14873_9770125.0Topological domainCytoplasmic
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368189-1816_8510593.0Topological domainExtracellular
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368189-18873_9770593.0Topological domainCytoplasmic
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368190-81016_851560760.0Topological domainExtracellular
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368190-810873_977560760.0Topological domainCytoplasmic
HgeneFCRL5chr1:157504404chr13:50080771ENST00000361835-817852_872560978.0TransmembraneHelical
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368188-14852_8720125.0TransmembraneHelical
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368189-18852_8720593.0TransmembraneHelical
HgeneFCRL5chr1:157504404chr13:50080771ENST00000368190-810852_872560760.0TransmembraneHelical


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Fusion Gene Sequence for FCRL5-PHF11


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>30034_30034_1_FCRL5-PHF11_FCRL5_chr1_157504404_ENST00000356953_PHF11_chr13_50080771_ENST00000378319_length(transcript)=2933nt_BP=1709nt
ATCTCAGCCCTTGGTGGTCCAGGTCTTCATGCTGCTGTGGGTGATATTACTGGTCCTGGTGCCATCCCCTGGGCAATTTCCAAGGACACC
CAGGCCCATTATTTTCCTCCAGCCTCCATGGACCACAGTCTTCCAAGGAGAGAGAGTGACCCTCACTTGCAAGGGATTTCGCTTCTACTC
ACCACAGAAAACAAAATGGTACCATCGGTACCTTGGGAAAGAAATACTAAGAGAAACCCCAGACAATATCCTTGAGGTTCAGGAATCTGG
AGAGTACAGATGCCAGGCCCAGGGCTCCCCTCTCAGTAGCCCTGTGCACTTGGATTTTTCTTCAGCTTCGCTGATCCTGCAAGCTCCACT
TTCTGTGTTTGAAGGAGACTCTGTGGTTCTGAGGTGCCGGGCAAAGGCGGAAGTAACACTGAATAATACTATTTACAAGAATGATAATGT
CCTGGCATTCCTTAATAAAAGAACTGACTTCCATATTCCTCATGCATGTCTCAAGGACAATGGTGCATATCGCTGTACTGGATATAAGGA
AAGTTGTTGCCCTGTTTCTTCCAATACAGTCAAAATCCAAGTCCAAGAGCCATTTACACGTCCAGTGCTGAGAGCCAGCTCCTTCCAGCC
CATCAGCGGGAACCCAGTGACCCTGACCTGTGAGACCCAGCTCTCTCTAGAGAGGTCAGATGTCCCGCTCCGGTTCCGCTTCTTCAGAGA
TGACCAGACCCTGGGATTAGGCTGGAGTCTCTCCCCGAATTTCCAGATTACTGCCATGTGGAGTAAAGATTCAGGGTTCTACTGGTGTAA
GGCAGCAACAATGCCTTACAGCGTCATATCTGACAGCCCGAGATCCTGGATACAGGTGCAGATCCCTGCATCTCATCCTGTCCTCACTCT
CAGCCCTGAAAAGGCTCTGAATTTTGAGGGAACCAAGGTGACACTTCACTGTGAAACCCAGGAAGATTCTCTGCGCACTTTGTACAGGTT
TTATCATGAGGGTGTCCCCCTGAGGCACAAGTCAGTCCGCTGTGAAAGGGGAGCATCCATCAGCTTCTCACTGACTACAGAGAATTCAGG
GAACTACTACTGCACAGCTGACAATGGCCTTGGCGCCAAGCCCAGTAAGGCTGTGAGCCTCTCAGTCACTGTTCCCGTGTCTCATCCTGT
CCTCAACCTCAGCTCTCCTGAGGACCTGATTTTTGAGGGAGCCAAGGTGACACTTCACTGTGAAGCCCAGAGAGGTTCACTCCCCATCCT
GTACCAGTTTCATCATGAGGGTGCTGCCCTGGAGCGTAGGTCGGCCAACTCTGCAGGAGGAGTGGCCATCAGCTTCTCTCTGACTGCAGA
GCATTCAGGGAACTACTACTGCACAGCTGACAATGGCTTTGGCCCCCAGCGCAGTAAGGCGGTGAGCCTCTCCGTCACTGTCCCTGTGTC
TCATCCTGTCCTCACCCTCAGCTCTGCTGAGGCCCTGACTTTTGAAGGAGCCACTGTGACACTTCACTGTGAAGTCCAGAGAGGTTCCCC
ACAAATCCTATACCAGTTTTATCATGAGGACATGCCCCTGTGGAGCAGCTCAACACCCTCTGTGGGAAGAGTGTCCTTCAGCTTCTCTCT
GACTGAAGGACATTCAGGGAATTACTACTGCACAGCTGACAATGGCTTTGGTCCCCAGCGCAGTGAAGTGGTGAGCCTTTTTGTCACTGG
TGTCTTTCAGGTTGCAGAAAAGATGGAAAAAAGGACATGTGCACTCTGCCCCAAAGATGTCGAATATAATGTCCTATACTTTGCACAATC
AGAGAATATAGCTGCTCATGAGAATTGTTTGCTGTATTCTTCAGGACTTGTGGAATGTGAGGATCAGGATCCACTTAATCCTGATAGAAG
TTTTGATGTGGAATCAGTAAAGAAAGAAATCCAGAGAGGAAGGAAGTTGAAATGCAAATTTTGTCATAAAAGAGGAGCCACCGTGGGATG
TGATTTAAAAAACTGTAACAAGAATTACCACTTTTTCTGTGCCAAGAAGGACGACGCAGTTCCACAGTCTGATGGAGTTCGAGGAATTTA
TAAACTGCTTTGCCAGCAACATGCTCAATTCCCGATCATCGCTCAAAGTGCTAAATTTTCAGGAGTGAAAAGAAAAAGAGGAAGGAAGAA
ACCCCTCTCAGGCAATCATGTACAGCCACCCGAAACAATGAAATGTAATACATTCATAAGACAAGTGAAAGAAGAGCATGGCAGACACAC
AGATGCAACTGTGAAAGTTCCTTTTCTTAAGAAATGCAAGGAAGCAGGACTTCTTAATTACTTACTTGAAGAAATATTAGACAAAGTTCA
TTCAATTCCAGAAAAACTCATGGATGAGACTACTTCAGAATCAGACTATGAAGAAATCGGGAGTGCACTTTTTGACTGTAGATTGTTCGA
AGACACATTTGTAAATTTTCAAGCAGCAATAGAGAAAAAAATTCATGCATCTCAACAAAGGTGGCAGCAGTTGAAGGAAGAGATTGAGCT
ACTTCAGGACTTAAAACAAACCTTGTGCTCTTTTCAAGAAAATAGAGATCTTATGTCAAGTTCTACATCAATATCATCCCTGTCTTATTA
GGGATTACCGTTTCCTAAGCCAAGAGTCATGTCAAATTGCAATCAGGCTCAAAACCAGAGACCAGGCTGTGAAATCCACACATCTTTAGA
ACTAGTCGTCTCCTCTTGGCCTCAGCAGCTCTTCCCTGTTCTTACTGGTTGACATTTTGATCACTCTTTGCACACTCTTGTGTTTTTTGC
TCACTGTCACATTCCCAGCACCTAGTATGCTCAGTAAATGTTTGTGGAATAAGTGCATAAAATGTTCTTAACCTTTGATTCTACTTACAG
CCCATGATAGCCTCTTAGATATAATAAATTTGGATTATACTACTTTACTTGTA

>30034_30034_1_FCRL5-PHF11_FCRL5_chr1_157504404_ENST00000356953_PHF11_chr13_50080771_ENST00000378319_length(amino acids)=866AA_BP=566
MVVQVFMLLWVILLVLVPSPGQFPRTPRPIIFLQPPWTTVFQGERVTLTCKGFRFYSPQKTKWYHRYLGKEILRETPDNILEVQESGEYR
CQAQGSPLSSPVHLDFSSASLILQAPLSVFEGDSVVLRCRAKAEVTLNNTIYKNDNVLAFLNKRTDFHIPHACLKDNGAYRCTGYKESCC
PVSSNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLGLGWSLSPNFQITAMWSKDSGFYWCKAAT
MPYSVISDSPRSWIQVQIPASHPVLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVRCERGASISFSLTTENSGNYY
CTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTAEHSG
NYYCTADNGFGPQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSSTPSVGRVSFSFSLTEG
HSGNYYCTADNGFGPQRSEVVSLFVTGVFQVAEKMEKRTCALCPKDVEYNVLYFAQSENIAAHENCLLYSSGLVECEDQDPLNPDRSFDV
ESVKKEIQRGRKLKCKFCHKRGATVGCDLKNCNKNYHFFCAKKDDAVPQSDGVRGIYKLLCQQHAQFPIIAQSAKFSGVKRKRGRKKPLS
GNHVQPPETMKCNTFIRQVKEEHGRHTDATVKVPFLKKCKEAGLLNYLLEEILDKVHSIPEKLMDETTSESDYEEIGSALFDCRLFEDTF
VNFQAAIEKKIHASQQRWQQLKEEIELLQDLKQTLCSFQENRDLMSSSTSISSLSY

--------------------------------------------------------------
>30034_30034_2_FCRL5-PHF11_FCRL5_chr1_157504404_ENST00000361835_PHF11_chr13_50080771_ENST00000378319_length(transcript)=3063nt_BP=1839nt
AATTCACTAATGCATTCTGCTCTTTTTGAGAGCACAGCTTCTCAGATGTGCTCCTTGGAGCTGGTGTGCAGTGTCCTGACTGTAAGATCA
AGTCCAAACCTGTTTTGGAATTGAGGAAACTTCTCTTTTGATCTCAGCCCTTGGTGGTCCAGGTCTTCATGCTGCTGTGGGTGATATTAC
TGGTCCTGGCTCCTGTCAGTGGACAGTTTGCAAGGACACCCAGGCCCATTATTTTCCTCCAGCCTCCATGGACCACAGTCTTCCAAGGAG
AGAGAGTGACCCTCACTTGCAAGGGATTTCGCTTCTACTCACCACAGAAAACAAAATGGTACCATCGGTACCTTGGGAAAGAAATACTAA
GAGAAACCCCAGACAATATCCTTGAGGTTCAGGAATCTGGAGAGTACAGATGCCAGGCCCAGGGCTCCCCTCTCAGTAGCCCTGTGCACT
TGGATTTTTCTTCAGCTTCGCTGATCCTGCAAGCTCCACTTTCTGTGTTTGAAGGAGACTCTGTGGTTCTGAGGTGCCGGGCAAAGGCGG
AAGTAACACTGAATAATACTATTTACAAGAATGATAATGTCCTGGCATTCCTTAATAAAAGAACTGACTTCCATATTCCTCATGCATGTC
TCAAGGACAATGGTGCATATCGCTGTACTGGATATAAGGAAAGTTGTTGCCCTGTTTCTTCCAATACAGTCAAAATCCAAGTCCAAGAGC
CATTTACACGTCCAGTGCTGAGAGCCAGCTCCTTCCAGCCCATCAGCGGGAACCCAGTGACCCTGACCTGTGAGACCCAGCTCTCTCTAG
AGAGGTCAGATGTCCCGCTCCGGTTCCGCTTCTTCAGAGATGACCAGACCCTGGGATTAGGCTGGAGTCTCTCCCCGAATTTCCAGATTA
CTGCCATGTGGAGTAAAGATTCAGGGTTCTACTGGTGTAAGGCAGCAACAATGCCTTACAGCGTCATATCTGACAGCCCGAGATCCTGGA
TACAGGTGCAGATCCCTGCATCTCATCCTGTCCTCACTCTCAGCCCTGAAAAGGCTCTGAATTTTGAGGGAACCAAGGTGACACTTCACT
GTGAAACCCAGGAAGATTCTCTGCGCACTTTGTACAGGTTTTATCATGAGGGTGTCCCCCTGAGGCACAAGTCAGTCCGCTGTGAAAGGG
GAGCATCCATCAGCTTCTCACTGACTACAGAGAATTCAGGGAACTACTACTGCACAGCTGACAATGGCCTTGGCGCCAAGCCCAGTAAGG
CTGTGAGCCTCTCAGTCACTGTTCCCGTGTCTCATCCTGTCCTCAACCTCAGCTCTCCTGAGGACCTGATTTTTGAGGGAGCCAAGGTGA
CACTTCACTGTGAAGCCCAGAGAGGTTCACTCCCCATCCTGTACCAGTTTCATCATGAGGGTGCTGCCCTGGAGCGTAGGTCGGCCAACT
CTGCAGGAGGAGTGGCCATCAGCTTCTCTCTGACTGCAGAGCATTCAGGGAACTACTACTGCACAGCTGACAATGGCTTTGGCCCCCAGC
GCAGTAAGGCGGTGAGCCTCTCCGTCACTGTCCCTGTGTCTCATCCTGTCCTCACCCTCAGCTCTGCTGAGGCCCTGACTTTTGAAGGAG
CCACTGTGACACTTCACTGTGAAGTCCAGAGAGGTTCCCCACAAATCCTATACCAGTTTTATCATGAGGACATGCCCCTGTGGAGCAGCT
CAACACCCTCTGTGGGAAGAGTGTCCTTCAGCTTCTCTCTGACTGAAGGACATTCAGGGAATTACTACTGCACAGCTGACAATGGCTTTG
GTCCCCAGCGCAGTGAAGTGGTGAGCCTTTTTGTCACTGGTGTCTTTCAGGTTGCAGAAAAGATGGAAAAAAGGACATGTGCACTCTGCC
CCAAAGATGTCGAATATAATGTCCTATACTTTGCACAATCAGAGAATATAGCTGCTCATGAGAATTGTTTGCTGTATTCTTCAGGACTTG
TGGAATGTGAGGATCAGGATCCACTTAATCCTGATAGAAGTTTTGATGTGGAATCAGTAAAGAAAGAAATCCAGAGAGGAAGGAAGTTGA
AATGCAAATTTTGTCATAAAAGAGGAGCCACCGTGGGATGTGATTTAAAAAACTGTAACAAGAATTACCACTTTTTCTGTGCCAAGAAGG
ACGACGCAGTTCCACAGTCTGATGGAGTTCGAGGAATTTATAAACTGCTTTGCCAGCAACATGCTCAATTCCCGATCATCGCTCAAAGTG
CTAAATTTTCAGGAGTGAAAAGAAAAAGAGGAAGGAAGAAACCCCTCTCAGGCAATCATGTACAGCCACCCGAAACAATGAAATGTAATA
CATTCATAAGACAAGTGAAAGAAGAGCATGGCAGACACACAGATGCAACTGTGAAAGTTCCTTTTCTTAAGAAATGCAAGGAAGCAGGAC
TTCTTAATTACTTACTTGAAGAAATATTAGACAAAGTTCATTCAATTCCAGAAAAACTCATGGATGAGACTACTTCAGAATCAGACTATG
AAGAAATCGGGAGTGCACTTTTTGACTGTAGATTGTTCGAAGACACATTTGTAAATTTTCAAGCAGCAATAGAGAAAAAAATTCATGCAT
CTCAACAAAGGTGGCAGCAGTTGAAGGAAGAGATTGAGCTACTTCAGGACTTAAAACAAACCTTGTGCTCTTTTCAAGAAAATAGAGATC
TTATGTCAAGTTCTACATCAATATCATCCCTGTCTTATTAGGGATTACCGTTTCCTAAGCCAAGAGTCATGTCAAATTGCAATCAGGCTC
AAAACCAGAGACCAGGCTGTGAAATCCACACATCTTTAGAACTAGTCGTCTCCTCTTGGCCTCAGCAGCTCTTCCCTGTTCTTACTGGTT
GACATTTTGATCACTCTTTGCACACTCTTGTGTTTTTTGCTCACTGTCACATTCCCAGCACCTAGTATGCTCAGTAAATGTTTGTGGAAT
AAGTGCATAAAATGTTCTTAACCTTTGATTCTACTTACAGCCCATGATAGCCTCTTAGATATAATAAATTTGGATTATACTACTTTACTT
GTA

>30034_30034_2_FCRL5-PHF11_FCRL5_chr1_157504404_ENST00000361835_PHF11_chr13_50080771_ENST00000378319_length(amino acids)=866AA_BP=566
MVVQVFMLLWVILLVLAPVSGQFARTPRPIIFLQPPWTTVFQGERVTLTCKGFRFYSPQKTKWYHRYLGKEILRETPDNILEVQESGEYR
CQAQGSPLSSPVHLDFSSASLILQAPLSVFEGDSVVLRCRAKAEVTLNNTIYKNDNVLAFLNKRTDFHIPHACLKDNGAYRCTGYKESCC
PVSSNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLGLGWSLSPNFQITAMWSKDSGFYWCKAAT
MPYSVISDSPRSWIQVQIPASHPVLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVRCERGASISFSLTTENSGNYY
CTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTAEHSG
NYYCTADNGFGPQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSSTPSVGRVSFSFSLTEG
HSGNYYCTADNGFGPQRSEVVSLFVTGVFQVAEKMEKRTCALCPKDVEYNVLYFAQSENIAAHENCLLYSSGLVECEDQDPLNPDRSFDV
ESVKKEIQRGRKLKCKFCHKRGATVGCDLKNCNKNYHFFCAKKDDAVPQSDGVRGIYKLLCQQHAQFPIIAQSAKFSGVKRKRGRKKPLS
GNHVQPPETMKCNTFIRQVKEEHGRHTDATVKVPFLKKCKEAGLLNYLLEEILDKVHSIPEKLMDETTSESDYEEIGSALFDCRLFEDTF
VNFQAAIEKKIHASQQRWQQLKEEIELLQDLKQTLCSFQENRDLMSSSTSISSLSY

--------------------------------------------------------------
>30034_30034_3_FCRL5-PHF11_FCRL5_chr1_157504404_ENST00000368190_PHF11_chr13_50080771_ENST00000378319_length(transcript)=2998nt_BP=1774nt
GTGCAGTGTCCTGACTGTAAGATCAAGTCCAAACCTGTTTTGGAATTGAGGAAACTTCTCTTTTGATCTCAGCCCTTGGTGGTCCAGGTC
TTCATGCTGCTGTGGGTGATATTACTGGTCCTGGCTCCTGTCAGTGGACAGTTTGCAAGGACACCCAGGCCCATTATTTTCCTCCAGCCT
CCATGGACCACAGTCTTCCAAGGAGAGAGAGTGACCCTCACTTGCAAGGGATTTCGCTTCTACTCACCACAGAAAACAAAATGGTACCAT
CGGTACCTTGGGAAAGAAATACTAAGAGAAACCCCAGACAATATCCTTGAGGTTCAGGAATCTGGAGAGTACAGATGCCAGGCCCAGGGC
TCCCCTCTCAGTAGCCCTGTGCACTTGGATTTTTCTTCAGCTTCGCTGATCCTGCAAGCTCCACTTTCTGTGTTTGAAGGAGACTCTGTG
GTTCTGAGGTGCCGGGCAAAGGCGGAAGTAACACTGAATAATACTATTTACAAGAATGATAATGTCCTGGCATTCCTTAATAAAAGAACT
GACTTCCATATTCCTCATGCATGTCTCAAGGACAATGGTGCATATCGCTGTACTGGATATAAGGAAAGTTGTTGCCCTGTTTCTTCCAAT
ACAGTCAAAATCCAAGTCCAAGAGCCATTTACACGTCCAGTGCTGAGAGCCAGCTCCTTCCAGCCCATCAGCGGGAACCCAGTGACCCTG
ACCTGTGAGACCCAGCTCTCTCTAGAGAGGTCAGATGTCCCGCTCCGGTTCCGCTTCTTCAGAGATGACCAGACCCTGGGATTAGGCTGG
AGTCTCTCCCCGAATTTCCAGATTACTGCCATGTGGAGTAAAGATTCAGGGTTCTACTGGTGTAAGGCAGCAACAATGCCTTACAGCGTC
ATATCTGACAGCCCGAGATCCTGGATACAGGTGCAGATCCCTGCATCTCATCCTGTCCTCACTCTCAGCCCTGAAAAGGCTCTGAATTTT
GAGGGAACCAAGGTGACACTTCACTGTGAAACCCAGGAAGATTCTCTGCGCACTTTGTACAGGTTTTATCATGAGGGTGTCCCCCTGAGG
CACAAGTCAGTCCGCTGTGAAAGGGGAGCATCCATCAGCTTCTCACTGACTACAGAGAATTCAGGGAACTACTACTGCACAGCTGACAAT
GGCCTTGGCGCCAAGCCCAGTAAGGCTGTGAGCCTCTCAGTCACTGTTCCCGTGTCTCATCCTGTCCTCAACCTCAGCTCTCCTGAGGAC
CTGATTTTTGAGGGAGCCAAGGTGACACTTCACTGTGAAGCCCAGAGAGGTTCACTCCCCATCCTGTACCAGTTTCATCATGAGGGTGCT
GCCCTGGAGCGTAGGTCGGCCAACTCTGCAGGAGGAGTGGCCATCAGCTTCTCTCTGACTGCAGAGCATTCAGGGAACTACTACTGCACA
GCTGACAATGGCTTTGGCCCCCAGCGCAGTAAGGCGGTGAGCCTCTCCGTCACTGTCCCTGTGTCTCATCCTGTCCTCACCCTCAGCTCT
GCTGAGGCCCTGACTTTTGAAGGAGCCACTGTGACACTTCACTGTGAAGTCCAGAGAGGTTCCCCACAAATCCTATACCAGTTTTATCAT
GAGGACATGCCCCTGTGGAGCAGCTCAACACCCTCTGTGGGAAGAGTGTCCTTCAGCTTCTCTCTGACTGAAGGACATTCAGGGAATTAC
TACTGCACAGCTGACAATGGCTTTGGTCCCCAGCGCAGTGAAGTGGTGAGCCTTTTTGTCACTGGTGTCTTTCAGGTTGCAGAAAAGATG
GAAAAAAGGACATGTGCACTCTGCCCCAAAGATGTCGAATATAATGTCCTATACTTTGCACAATCAGAGAATATAGCTGCTCATGAGAAT
TGTTTGCTGTATTCTTCAGGACTTGTGGAATGTGAGGATCAGGATCCACTTAATCCTGATAGAAGTTTTGATGTGGAATCAGTAAAGAAA
GAAATCCAGAGAGGAAGGAAGTTGAAATGCAAATTTTGTCATAAAAGAGGAGCCACCGTGGGATGTGATTTAAAAAACTGTAACAAGAAT
TACCACTTTTTCTGTGCCAAGAAGGACGACGCAGTTCCACAGTCTGATGGAGTTCGAGGAATTTATAAACTGCTTTGCCAGCAACATGCT
CAATTCCCGATCATCGCTCAAAGTGCTAAATTTTCAGGAGTGAAAAGAAAAAGAGGAAGGAAGAAACCCCTCTCAGGCAATCATGTACAG
CCACCCGAAACAATGAAATGTAATACATTCATAAGACAAGTGAAAGAAGAGCATGGCAGACACACAGATGCAACTGTGAAAGTTCCTTTT
CTTAAGAAATGCAAGGAAGCAGGACTTCTTAATTACTTACTTGAAGAAATATTAGACAAAGTTCATTCAATTCCAGAAAAACTCATGGAT
GAGACTACTTCAGAATCAGACTATGAAGAAATCGGGAGTGCACTTTTTGACTGTAGATTGTTCGAAGACACATTTGTAAATTTTCAAGCA
GCAATAGAGAAAAAAATTCATGCATCTCAACAAAGGTGGCAGCAGTTGAAGGAAGAGATTGAGCTACTTCAGGACTTAAAACAAACCTTG
TGCTCTTTTCAAGAAAATAGAGATCTTATGTCAAGTTCTACATCAATATCATCCCTGTCTTATTAGGGATTACCGTTTCCTAAGCCAAGA
GTCATGTCAAATTGCAATCAGGCTCAAAACCAGAGACCAGGCTGTGAAATCCACACATCTTTAGAACTAGTCGTCTCCTCTTGGCCTCAG
CAGCTCTTCCCTGTTCTTACTGGTTGACATTTTGATCACTCTTTGCACACTCTTGTGTTTTTTGCTCACTGTCACATTCCCAGCACCTAG
TATGCTCAGTAAATGTTTGTGGAATAAGTGCATAAAATGTTCTTAACCTTTGATTCTACTTACAGCCCATGATAGCCTCTTAGATATAAT
AAATTTGGATTATACTACTTTACTTGTA

>30034_30034_3_FCRL5-PHF11_FCRL5_chr1_157504404_ENST00000368190_PHF11_chr13_50080771_ENST00000378319_length(amino acids)=866AA_BP=566
MVVQVFMLLWVILLVLAPVSGQFARTPRPIIFLQPPWTTVFQGERVTLTCKGFRFYSPQKTKWYHRYLGKEILRETPDNILEVQESGEYR
CQAQGSPLSSPVHLDFSSASLILQAPLSVFEGDSVVLRCRAKAEVTLNNTIYKNDNVLAFLNKRTDFHIPHACLKDNGAYRCTGYKESCC
PVSSNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLGLGWSLSPNFQITAMWSKDSGFYWCKAAT
MPYSVISDSPRSWIQVQIPASHPVLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVRCERGASISFSLTTENSGNYY
CTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGAALERRSANSAGGVAISFSLTAEHSG
NYYCTADNGFGPQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSSTPSVGRVSFSFSLTEG
HSGNYYCTADNGFGPQRSEVVSLFVTGVFQVAEKMEKRTCALCPKDVEYNVLYFAQSENIAAHENCLLYSSGLVECEDQDPLNPDRSFDV
ESVKKEIQRGRKLKCKFCHKRGATVGCDLKNCNKNYHFFCAKKDDAVPQSDGVRGIYKLLCQQHAQFPIIAQSAKFSGVKRKRGRKKPLS
GNHVQPPETMKCNTFIRQVKEEHGRHTDATVKVPFLKKCKEAGLLNYLLEEILDKVHSIPEKLMDETTSESDYEEIGSALFDCRLFEDTF
VNFQAAIEKKIHASQQRWQQLKEEIELLQDLKQTLCSFQENRDLMSSSTSISSLSY

--------------------------------------------------------------
>30034_30034_4_FCRL5-PHF11_FCRL5_chr1_157504404_ENST00000368191_PHF11_chr13_50080771_ENST00000378319_length(transcript)=2781nt_BP=1557nt
GAGAGCACAGCTTCTCAGATGTGCTCCTTGGAGCTGGTGTGCAGTGTCCTGACTGTAAGATCAAGTCCAAACCTGTTTTGGAATTGAGGA
AACTTCTCTTTTGATCTCAGCCCTTGGTGGTCCAGGTCTTCATGCTGCTGTGGGTGATATTACTGGTCCTGGCTCCTGTCAGTGGACAGT
TTGCTTCGCTGATCCTGCAAGCTCCACTTTCTGTGTTTGAAGGAGACTCTGTGGTTCTGAGGTGCCGGGCAAAGGCGGAAGTAACACTGA
ATAATACTATTTACAAGAATGATAATGTCCTGGCATTCCTTAATAAAAGAACTGACTTCCATATTCCTCATGCATGTCTCAAGGACAATG
GTGCATATCGCTGTACTGGATATAAGGAAAGTTGTTGCCCTGTTTCTTCCAATACAGTCAAAATCCAAGTCCAAGAGCCATTTACACGTC
CAGTGCTGAGAGCCAGCTCCTTCCAGCCCATCAGCGGGAACCCAGTGACCCTGACCTGTGAGACCCAGCTCTCTCTAGAGAGGTCAGATG
TCCCGCTCCGGTTCCGCTTCTTCAGAGATGACCAGACCCTGGGATTAGGCTGGAGTCTCTCCCCGAATTTCCAGATTACTGCCATGTGGA
GTAAAGATTCAGGGTTCTACTGGTGTAAGGCAGCAACAATGCCTTACAGCGTCATATCTGACAGCCCGAGATCCTGGATACAGGTGCAGA
TCCCTGCATCTCATCCTGTCCTCACTCTCAGCCCTGAAAAGGCTCTGAATTTTGAGGGAACCAAGGTGACACTTCACTGTGAAACCCAGG
AAGATTCTCTGCGCACTTTGTACAGGTTTTATCATGAGGGTGTCCCCCTGAGGCACAAGTCAGTCCGCTGTGAAAGGGGAGCATCCATCA
GCTTCTCACTGACTACAGAGAATTCAGGGAACTACTACTGCACAGCTGACAATGGCCTTGGCGCCAAGCCCAGTAAGGCTGTGAGCCTCT
CAGTCACTGTTCCCGTGTCTCATCCTGTCCTCAACCTCAGCTCTCCTGAGGACCTGATTTTTGAGGGAGCCAAGGTGACACTTCACTGTG
AAGCCCAGAGAGGTTCACTCCCCATCCTGTACCAGTTTCATCATGAGGGTGCTGCCCTGGAGCGTAGGTCGGCCAACTCTGCAGGAGGAG
TGGCCATCAGCTTCTCTCTGACTGCAGAGCATTCAGGGAACTACTACTGCACAGCTGACAATGGCTTTGGCCCCCAGCGCAGTAAGGCGG
TGAGCCTCTCCGTCACTGTCCCTGTGTCTCATCCTGTCCTCACCCTCAGCTCTGCTGAGGCCCTGACTTTTGAAGGAGCCACTGTGACAC
TTCACTGTGAAGTCCAGAGAGGTTCCCCACAAATCCTATACCAGTTTTATCATGAGGACATGCCCCTGTGGAGCAGCTCAACACCCTCTG
TGGGAAGAGTGTCCTTCAGCTTCTCTCTGACTGAAGGACATTCAGGGAATTACTACTGCACAGCTGACAATGGCTTTGGTCCCCAGCGCA
GTGAAGTGGTGAGCCTTTTTGTCACTGGTGTCTTTCAGGTTGCAGAAAAGATGGAAAAAAGGACATGTGCACTCTGCCCCAAAGATGTCG
AATATAATGTCCTATACTTTGCACAATCAGAGAATATAGCTGCTCATGAGAATTGTTTGCTGTATTCTTCAGGACTTGTGGAATGTGAGG
ATCAGGATCCACTTAATCCTGATAGAAGTTTTGATGTGGAATCAGTAAAGAAAGAAATCCAGAGAGGAAGGAAGTTGAAATGCAAATTTT
GTCATAAAAGAGGAGCCACCGTGGGATGTGATTTAAAAAACTGTAACAAGAATTACCACTTTTTCTGTGCCAAGAAGGACGACGCAGTTC
CACAGTCTGATGGAGTTCGAGGAATTTATAAACTGCTTTGCCAGCAACATGCTCAATTCCCGATCATCGCTCAAAGTGCTAAATTTTCAG
GAGTGAAAAGAAAAAGAGGAAGGAAGAAACCCCTCTCAGGCAATCATGTACAGCCACCCGAAACAATGAAATGTAATACATTCATAAGAC
AAGTGAAAGAAGAGCATGGCAGACACACAGATGCAACTGTGAAAGTTCCTTTTCTTAAGAAATGCAAGGAAGCAGGACTTCTTAATTACT
TACTTGAAGAAATATTAGACAAAGTTCATTCAATTCCAGAAAAACTCATGGATGAGACTACTTCAGAATCAGACTATGAAGAAATCGGGA
GTGCACTTTTTGACTGTAGATTGTTCGAAGACACATTTGTAAATTTTCAAGCAGCAATAGAGAAAAAAATTCATGCATCTCAACAAAGGT
GGCAGCAGTTGAAGGAAGAGATTGAGCTACTTCAGGACTTAAAACAAACCTTGTGCTCTTTTCAAGAAAATAGAGATCTTATGTCAAGTT
CTACATCAATATCATCCCTGTCTTATTAGGGATTACCGTTTCCTAAGCCAAGAGTCATGTCAAATTGCAATCAGGCTCAAAACCAGAGAC
CAGGCTGTGAAATCCACACATCTTTAGAACTAGTCGTCTCCTCTTGGCCTCAGCAGCTCTTCCCTGTTCTTACTGGTTGACATTTTGATC
ACTCTTTGCACACTCTTGTGTTTTTTGCTCACTGTCACATTCCCAGCACCTAGTATGCTCAGTAAATGTTTGTGGAATAAGTGCATAAAA
TGTTCTTAACCTTTGATTCTACTTACAGCCCATGATAGCCTCTTAGATATAATAAATTTGGATTATACTACTTTACTTGTA

>30034_30034_4_FCRL5-PHF11_FCRL5_chr1_157504404_ENST00000368191_PHF11_chr13_50080771_ENST00000378319_length(amino acids)=781AA_BP=481
MVVQVFMLLWVILLVLAPVSGQFASLILQAPLSVFEGDSVVLRCRAKAEVTLNNTIYKNDNVLAFLNKRTDFHIPHACLKDNGAYRCTGY
KESCCPVSSNTVKIQVQEPFTRPVLRASSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQTLGLGWSLSPNFQITAMWSKDSGFYW
CKAATMPYSVISDSPRSWIQVQIPASHPVLTLSPEKALNFEGTKVTLHCETQEDSLRTLYRFYHEGVPLRHKSVRCERGASISFSLTTEN
SGNYYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLIFEGAKVTLHCEAQRGSLPILYQFHHEGAALERRSANSAGGVAISFSLT
AEHSGNYYCTADNGFGPQRSKAVSLSVTVPVSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFYHEDMPLWSSSTPSVGRVSFSF
SLTEGHSGNYYCTADNGFGPQRSEVVSLFVTGVFQVAEKMEKRTCALCPKDVEYNVLYFAQSENIAAHENCLLYSSGLVECEDQDPLNPD
RSFDVESVKKEIQRGRKLKCKFCHKRGATVGCDLKNCNKNYHFFCAKKDDAVPQSDGVRGIYKLLCQQHAQFPIIAQSAKFSGVKRKRGR
KKPLSGNHVQPPETMKCNTFIRQVKEEHGRHTDATVKVPFLKKCKEAGLLNYLLEEILDKVHSIPEKLMDETTSESDYEEIGSALFDCRL
FEDTFVNFQAAIEKKIHASQQRWQQLKEEIELLQDLKQTLCSFQENRDLMSSSTSISSLSY

--------------------------------------------------------------

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Fusion Gene PPI Analysis for FCRL5-PHF11


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for FCRL5-PHF11


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for FCRL5-PHF11


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource