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in Kim Lab

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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ARHGAP24-BANK1 (FusionGDB2 ID:HG83478TG55024)

Fusion Gene Summary for ARHGAP24-BANK1

check button Fusion gene summary
Fusion gene informationFusion gene name: ARHGAP24-BANK1
Fusion gene ID: hg83478tg55024
HgeneTgene
Gene symbol

ARHGAP24

BANK1

Gene ID

83478

55024

Gene nameRho GTPase activating protein 24B cell scaffold protein with ankyrin repeats 1
SynonymsFILGAP|RC-GAP72|RCGAP72|p73|p73RhoGAPBANK
Cytomap('ARHGAP24')('BANK1')

4q21.23-q21.3

4q24

Type of geneprotein-codingprotein-coding
Descriptionrho GTPase-activating protein 24RAC1- and CDC42-specific GTPase-activating protein of 72 kDafilamin-A-associated RhoGAPrhoGAP of 73 kDasarcoma antigen NY-SAR-88B-cell scaffold protein with ankyrin repeats
Modification date2020031320200313
UniProtAcc.

Q8NDB2

Ensembl transtripts involved in fusion geneENST00000506421, ENST00000395184, 
ENST00000503995, ENST00000264343, 
ENST00000395183, 
Fusion gene scores* DoF score11 X 10 X 6=6606 X 6 X 4=144
# samples 146
** MAII scorelog2(14/660*10)=-2.23703919730085
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(6/144*10)=-1.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ARHGAP24 [Title/Abstract] AND BANK1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointARHGAP24(86491874)-BANK1(102942670), # samples:1
Anticipated loss of major functional domain due to fusion event.ARHGAP24-BANK1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ARHGAP24-BANK1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneBANK1

GO:0042113

B cell activation

11782428


check buttonFusion gene breakpoints across ARHGAP24 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across BANK1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand


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Fusion Gene ORF analysis for ARHGAP24-BANK1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000395184ENST00000504592ARHGAP24chr486491874+BANK1chr4102942670+0.0006161410.9993838
ENST00000395184ENST00000322953ARHGAP24chr486491874+BANK1chr4102942670+0.0006691520.9993309
ENST00000395184ENST00000428908ARHGAP24chr486491874+BANK1chr4102942670+0.0006120040.999388
ENST00000395184ENST00000508653ARHGAP24chr486491874+BANK1chr4102942670+0.0022350030.99776495
ENST00000395184ENST00000444316ARHGAP24chr486491874+BANK1chr4102942670+0.0006691520.9993309
ENST00000503995ENST00000504592ARHGAP24chr486491874+BANK1chr4102942670+0.0006028120.99939716
ENST00000503995ENST00000322953ARHGAP24chr486491874+BANK1chr4102942670+0.000667630.99933237
ENST00000503995ENST00000428908ARHGAP24chr486491874+BANK1chr4102942670+0.0005987860.9994012
ENST00000503995ENST00000508653ARHGAP24chr486491874+BANK1chr4102942670+0.0024499170.9975501
ENST00000503995ENST00000444316ARHGAP24chr486491874+BANK1chr4102942670+0.000667630.99933237

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Fusion Genomic Features for ARHGAP24-BANK1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ARHGAP24chr486491874+BANK1chr4102942670+0.0116844330.9883156
ARHGAP24chr486491874+BANK1chr4102942670+0.0116844330.9883156

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ARHGAP24-BANK1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr4:86491874/chr4:102942670)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.BANK1

Q8NDB2

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Involved in B-cell receptor (BCR)-induced Ca(2+) mobilization from intracellular stores. Promotes Lyn-mediated phosphorylation of IP3 receptors 1 and 2. {ECO:0000269|PubMed:11782428}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneBANK1chr4:86491874chr4:102942670ENST00000428908516342_371269807.0RepeatNote=ANK 1
TgeneBANK1chr4:86491874chr4:102942670ENST00000428908516378_408269807.0RepeatNote=ANK 2
TgeneBANK1chr4:86491874chr4:102942670ENST00000444316617378_408372963.3333333333334RepeatNote=ANK 2
TgeneBANK1chr4:86491874chr4:102942670ENST00000508653515342_371269653.0RepeatNote=ANK 1
TgeneBANK1chr4:86491874chr4:102942670ENST00000508653515378_408269653.0RepeatNote=ANK 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneARHGAP24chr4:86491874chr4:102942670ENST00000264343+17649_7290656.0Coiled coilOntology_term=ECO:0000255
HgeneARHGAP24chr4:86491874chr4:102942670ENST00000395183+18649_7290654.0Coiled coilOntology_term=ECO:0000255
HgeneARHGAP24chr4:86491874chr4:102942670ENST00000395184+210649_72960749.0Coiled coilOntology_term=ECO:0000255
HgeneARHGAP24chr4:86491874chr4:102942670ENST00000503995+26649_72960247.0Coiled coilOntology_term=ECO:0000255
HgeneARHGAP24chr4:86491874chr4:102942670ENST00000264343+17135_3290656.0DomainRho-GAP
HgeneARHGAP24chr4:86491874chr4:102942670ENST00000264343+1719_1250656.0DomainPH
HgeneARHGAP24chr4:86491874chr4:102942670ENST00000395183+18135_3290654.0DomainRho-GAP
HgeneARHGAP24chr4:86491874chr4:102942670ENST00000395183+1819_1250654.0DomainPH
HgeneARHGAP24chr4:86491874chr4:102942670ENST00000395184+210135_32960749.0DomainRho-GAP
HgeneARHGAP24chr4:86491874chr4:102942670ENST00000395184+21019_12560749.0DomainPH
HgeneARHGAP24chr4:86491874chr4:102942670ENST00000503995+26135_32960247.0DomainRho-GAP
HgeneARHGAP24chr4:86491874chr4:102942670ENST00000503995+2619_12560247.0DomainPH
TgeneBANK1chr4:86491874chr4:102942670ENST00000322953617200_327402916.3333333333334DomainDBB
TgeneBANK1chr4:86491874chr4:102942670ENST0000032295361725_153402916.3333333333334DomainTIR
TgeneBANK1chr4:86491874chr4:102942670ENST00000428908516200_327269807.0DomainDBB
TgeneBANK1chr4:86491874chr4:102942670ENST0000042890851625_153269807.0DomainTIR
TgeneBANK1chr4:86491874chr4:102942670ENST00000444316617200_327372963.3333333333334DomainDBB
TgeneBANK1chr4:86491874chr4:102942670ENST0000044431661725_153372963.3333333333334DomainTIR
TgeneBANK1chr4:86491874chr4:102942670ENST000005045921021200_327387994.6666666666666DomainDBB
TgeneBANK1chr4:86491874chr4:102942670ENST00000504592102125_153387994.6666666666666DomainTIR
TgeneBANK1chr4:86491874chr4:102942670ENST00000508653515200_327269653.0DomainDBB
TgeneBANK1chr4:86491874chr4:102942670ENST0000050865351525_153269653.0DomainTIR
TgeneBANK1chr4:86491874chr4:102942670ENST00000322953617342_371402916.3333333333334RepeatNote=ANK 1
TgeneBANK1chr4:86491874chr4:102942670ENST00000322953617378_408402916.3333333333334RepeatNote=ANK 2
TgeneBANK1chr4:86491874chr4:102942670ENST00000444316617342_371372963.3333333333334RepeatNote=ANK 1
TgeneBANK1chr4:86491874chr4:102942670ENST000005045921021342_371387994.6666666666666RepeatNote=ANK 1
TgeneBANK1chr4:86491874chr4:102942670ENST000005045921021378_408387994.6666666666666RepeatNote=ANK 2


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Fusion Gene Sequence for ARHGAP24-BANK1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>6013_6013_1_ARHGAP24-BANK1_ARHGAP24_chr4_86491874_ENST00000395184_BANK1_chr4_102942670_ENST00000322953_length(transcript)=2538nt_BP=646nt
TTGTACTGTATATTTACACATTCACACACAATCACCCTTTCTAACTTCTGGGACTCTTTGCGCAACTGCTAGGATTTCTCAAGTGCATGT
GGCAACACAGCCCAGCTCCGGGTGGAAACCAGCAGGGCTCTGGAGGGGCTCGGAGACCAGGGGAGCTGTCAAGGCTGCGGCGGGGACCAG
AGAGGAGCCTGGCGGGGGTGGCTGGGTGGCTGGGGGAATCCCCCCAACTTCCCATCGCAGGCGCAGCTCTCTCGGCCGCCTATTTCCTCC
GAAACCCGCGCTGCGGAGCAGCCCAGTGCATAGAGTTCAACACTTCCCCTTGTTGTGGAAAGTAAAGGAGCCTCACTACCACCTTTTTTT
CTTTGCGTTTTCTTACTGCTGGTCCTGGGAGCCTTTTCCTTCGGAGCAGCAGCCCTGTCCGGCATCTGTCTTGAGCTCCCAGCAAGGAAA
GTCCATCAGCTTGATAATGGAGGAGAACAATGACTCCACGGAGAACCCCCAACAAGGCCAAGGGCGGCAGAATGCCATCAAGTGTGGGTG
GCTGAGGAAGCAAGGAGGCTTTGTCAAGACTTGGCATACTCGCTGGTTTGTGCTCAAGGGGGATCAGCTCTATTATTTCAAAGATGAAGA
TGAAACCAAGCCCTTGATCCAAGAAATTGACATAAATAATGAGCAAGAAAATGATTATGAAGAGGATATTGCCTCATTTTCCACATATAT
TCCTTCCACACAGAACCCAGCATTTCATCATGAAAGCAGGAAGACATACGGGCAGAGTGCAGATGGAGCTGAGGCAAATGAAATGGAAGG
GGAAGGAAAACAGAATGGATCAGGCATGGAGACCAAACACAGCCCACTAGAGGTTGGCAGTGAGAGTTCTGAAGACCAGTATGATGACTT
GTATGTGTTCATTCCTGGTGCTGATCCAGAAAATAATTCACAAGAGCCACTCATGAGCAGCAGACCTCCTCTCCCCCCGCCGCGACCTGT
AGCTAATGCCTTCCAACTGGAAAGACCTCACTTCACCTTACCAGGGACAATGGTGGAAGGCCAAATGGAAAGAAGTCAAAACTGGGGTCA
TCCTGGTGTTAGACAAGAAACAGGAGATGAACCCAAAGGAGAAAAAGAGAAGAAAGAAGAGGAAAAAGAGCAGGAGGAGGAAGAAGACCC
ATATACTTTTGCTGAGATTGATGACAGTGAATATGACATGATATTGGCCAATCTGAGTATAAAGAAAAAAACTGGGAGTCGGTCTTTCAT
TATAAATAGACCTCCTGCCCCCACACCCCGACCCACAAGTATACCTCCAAAAGAGGAAACTACACCTTACATAGCTCAAGTGTTTCAACA
AAAGACAGCCAGAAGACAATCTGATGATGACAAGTTCTGTGGTCTTCCTAAGAAACAAGACAGAGCTCGGATAGAGAGTCCAGCCTTTTC
TACTCTCAGGGGCTGTCTAACTGATGGTCAGGAAGAACTCATCCTCCTGCAGGAGAAAGTAAAGAATGGGAAAATGTCTATGGATGAAGC
TCTGGAGAAATTTAAACACTGGCAGATGGGAAAAAGTGGCCTGGAAATGATTCAGCAGGAGAAATTACGACAACTACGAGACTGCATTAT
TGGGAAAAGGCCAGAAGAAGAAAATGTCTATAATAAACTCACCATTGTGCACCATCCAGGTGGTAAGGAAACTGCCCACAATGAAAATAA
GTTTTATAATGTACACTTCAGCAATAAGCTTCCTGCTCGACCCCAAGTTGAAAAGGAATTTGGTTTCTGTTGCAAGAAAGATCATTAAAG
AAGGTTATTATAATGAAACTCACGAATCTACGGACATTTTGCTTTCAGGGTGAAGCAAGCTTGAATTTGGATTGCCTGCTCTCTTTAAAG
CGAATTCATACTATGACAGCAGAAACAAAACTTCAGATTTCAGAATTTGTTATTGGCAAAATTTATTCTCATTATACCTGCTTCATATGG
GTATATTACTATTAAAACAGAATACCATAGAGTAATTGCATTATTTGAAAATTCTCTCATTTTACAATGCACTTCACCAATGAAACAGCT
AATTTCCATTTTGAAAATTAAAAGAAAACAGCACAGAGAAGTTAAATGCGGTGTAGCAAAGTTATGGGGTCTGCTTGAGGGCACTAACCT
CAACAGATTATTCCTCCTCTCCTTAGAATAACCATGAAAATACAAATTTACTTAGCACATTTTTGCTTTTTAAGTAGCTGGTTCATTTTC
TGAATTTCTCACATTCAGAGTTCCAGTCATTATTGTTACATCATGTTTGCAGAAACCTTGTCTTATTTAGTGTCTATTTGCATATAACCC
TGAAAACATTATTATTTGAAAACTTTTCTATATCTCAAATTAATATACATTTTCATAACCTACCTTTGTATTAAGACTTGCAATTTTATC
AATCTATTATTTCTTAGAAACAATTTACTAGCTTAGAATAGAAAGCAATGTTATCGTCATATAATTTTCATGTACAAATGCCACAAATAA

>6013_6013_1_ARHGAP24-BANK1_ARHGAP24_chr4_86491874_ENST00000395184_BANK1_chr4_102942670_ENST00000322953_length(amino acids)=505AA_BP=122
MRSSPVHRVQHFPLLWKVKEPHYHLFFFAFSYCWSWEPFPSEQQPCPASVLSSQQGKSISLIMEENNDSTENPQQGQGRQNAIKCGWLRK
QGGFVKTWHTRWFVLKGDQLYYFKDEDETKPLIQEIDINNEQENDYEEDIASFSTYIPSTQNPAFHHESRKTYGQSADGAEANEMEGEGK
QNGSGMETKHSPLEVGSESSEDQYDDLYVFIPGADPENNSQEPLMSSRPPLPPPRPVANAFQLERPHFTLPGTMVEGQMERSQNWGHPGV
RQETGDEPKGEKEKKEEEKEQEEEEDPYTFAEIDDSEYDMILANLSIKKKTGSRSFIINRPPAPTPRPTSIPPKEETTPYIAQVFQQKTA
RRQSDDDKFCGLPKKQDRARIESPAFSTLRGCLTDGQEELILLQEKVKNGKMSMDEALEKFKHWQMGKSGLEMIQQEKLRQLRDCIIGKR

--------------------------------------------------------------
>6013_6013_2_ARHGAP24-BANK1_ARHGAP24_chr4_86491874_ENST00000395184_BANK1_chr4_102942670_ENST00000428908_length(transcript)=2609nt_BP=646nt
TTGTACTGTATATTTACACATTCACACACAATCACCCTTTCTAACTTCTGGGACTCTTTGCGCAACTGCTAGGATTTCTCAAGTGCATGT
GGCAACACAGCCCAGCTCCGGGTGGAAACCAGCAGGGCTCTGGAGGGGCTCGGAGACCAGGGGAGCTGTCAAGGCTGCGGCGGGGACCAG
AGAGGAGCCTGGCGGGGGTGGCTGGGTGGCTGGGGGAATCCCCCCAACTTCCCATCGCAGGCGCAGCTCTCTCGGCCGCCTATTTCCTCC
GAAACCCGCGCTGCGGAGCAGCCCAGTGCATAGAGTTCAACACTTCCCCTTGTTGTGGAAAGTAAAGGAGCCTCACTACCACCTTTTTTT
CTTTGCGTTTTCTTACTGCTGGTCCTGGGAGCCTTTTCCTTCGGAGCAGCAGCCCTGTCCGGCATCTGTCTTGAGCTCCCAGCAAGGAAA
GTCCATCAGCTTGATAATGGAGGAGAACAATGACTCCACGGAGAACCCCCAACAAGGCCAAGGGCGGCAGAATGCCATCAAGTGTGGGTG
GCTGAGGAAGCAAGGAGGCTTTGTCAAGACTTGGCATACTCGCTGGTTTGTGCTCAAGGGGGATCAGCTCTATTATTTCAAAGATGAAGA
TGAAACCAAGCCCTTGATCCAAGAAATTGACATAAATAATGAGCAAGAAAATGATTATGAAGAGGATATTGCCTCATTTTCCACATATAT
TCCTTCCACACAGAACCCAGCATTTCATCATGAAAGCAGGAAGACATACGGGCAGAGTGCAGATGGAGCTGAGGCAAATGAAATGGAAGG
GGAAGGAAAACAGAATGGATCAGGCATGGAGACCAAACACAGCCCACTAGAGGTTGGCAGTGAGAGTTCTGAAGACCAGTATGATGACTT
GTATGTGTTCATTCCTGGTGCTGATCCAGAAAATAATTCACAAGAGCCACTCATGAGCAGCAGACCTCCTCTCCCCCCGCCGCGACCTGT
AGCTAATGCCTTCCAACTGGAAAGACCTCACTTCACCTTACCAGGGACAATGGTGGAAGGCCAAATGGAAAGAAGTCAAAACTGGGGTCA
TCCTGGTGTTAGACAAGAAACAGGAGATGAACCCAAAGGAGAAAAAGAGAAGAAAGAAGAGGAAAAAGAGCAGGAGGAGGAAGAAGACCC
ATATACTTTTGCTGAGATTGATGACAGTGAATATGACATGATATTGGCCAATCTGAGTATAAAGAAAAAAACTGGGAGTCGGTCTTTCAT
TATAAATAGACCTCCTGCCCCCACACCCCGACCCACAAGTATACCTCCAAAAGAGGAAACTACACCTTACATAGCTCAAGTGTTTCAACA
AAAGACAGCCAGAAGACAATCTGATGATGACAAGTTCTGTGGTCTTCCTAAGAAACAAGACAGAGCTCGGATAGAGAGTCCAGCCTTTTC
TACTCTCAGGGGCTGTCTAACTGATGGTCAGGAAGAACTCATCCTCCTGCAGGAGAAAGTAAAGAATGGGAAAATGTCTATGGATGAAGC
TCTGGAGAAATTTAAACACTGGCAGATGGGAAAAAGTGGCCTGGAAATGATTCAGCAGGAGAAATTACGACAACTACGAGACTGCATTAT
TGGGAAAAGGCCAGAAGAAGAAAATGTCTATAATAAACTCACCATTGTGCACCATCCAGGTGGTAAGGAAACTGCCCACAATGAAAATAA
GTTTTATAATGTACACTTCAGCAATAAGCTTCCTGCTCGACCCCAAGTTGAAAAGGAATTTGGTTTCTGTTGCAAGAAAGATCATTAAAG
AAGGTTATTATAATGAAACTCACGAATCTACGGACATTTTGCTTTCAGGGTGAAGCAAGCTTGAATTTGGATTGCCTGCTCTCTTTAAAG
CGAATTCATACTATGACAGCAGAAACAAAACTTCAGATTTCAGAATTTGTTATTGGCAAAATTTATTCTCATTATACCTGCTTCATATGG
GTATATTACTATTAAAACAGAATACCATAGAGTAATTGCATTATTTGAAAATTCTCTCATTTTACAATGCACTTCACCAATGAAACAGCT
AATTTCCATTTTGAAAATTAAAAGAAAACAGCACAGAGAAGTTAAATGCGGTGTAGCAAAGTTATGGGGTCTGCTTGAGGGCACTAACCT
CAACAGATTATTCCTCCTCTCCTTAGAATAACCATGAAAATACAAATTTACTTAGCACATTTTTGCTTTTTAAGTAGCTGGTTCATTTTC
TGAATTTCTCACATTCAGAGTTCCAGTCATTATTGTTACATCATGTTTGCAGAAACCTTGTCTTATTTAGTGTCTATTTGCATATAACCC
TGAAAACATTATTATTTGAAAACTTTTCTATATCTCAAATTAATATACATTTTCATAACCTACCTTTGTATTAAGACTTGCAATTTTATC
AATCTATTATTTCTTAGAAACAATTTACTAGCTTAGAATAGAAAGCAATGTTATCGTCATATAATTTTCATGTACAAATGCCACAAATAA

>6013_6013_2_ARHGAP24-BANK1_ARHGAP24_chr4_86491874_ENST00000395184_BANK1_chr4_102942670_ENST00000428908_length(amino acids)=505AA_BP=122
MRSSPVHRVQHFPLLWKVKEPHYHLFFFAFSYCWSWEPFPSEQQPCPASVLSSQQGKSISLIMEENNDSTENPQQGQGRQNAIKCGWLRK
QGGFVKTWHTRWFVLKGDQLYYFKDEDETKPLIQEIDINNEQENDYEEDIASFSTYIPSTQNPAFHHESRKTYGQSADGAEANEMEGEGK
QNGSGMETKHSPLEVGSESSEDQYDDLYVFIPGADPENNSQEPLMSSRPPLPPPRPVANAFQLERPHFTLPGTMVEGQMERSQNWGHPGV
RQETGDEPKGEKEKKEEEKEQEEEEDPYTFAEIDDSEYDMILANLSIKKKTGSRSFIINRPPAPTPRPTSIPPKEETTPYIAQVFQQKTA
RRQSDDDKFCGLPKKQDRARIESPAFSTLRGCLTDGQEELILLQEKVKNGKMSMDEALEKFKHWQMGKSGLEMIQQEKLRQLRDCIIGKR

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>6013_6013_3_ARHGAP24-BANK1_ARHGAP24_chr4_86491874_ENST00000395184_BANK1_chr4_102942670_ENST00000444316_length(transcript)=2538nt_BP=646nt
TTGTACTGTATATTTACACATTCACACACAATCACCCTTTCTAACTTCTGGGACTCTTTGCGCAACTGCTAGGATTTCTCAAGTGCATGT
GGCAACACAGCCCAGCTCCGGGTGGAAACCAGCAGGGCTCTGGAGGGGCTCGGAGACCAGGGGAGCTGTCAAGGCTGCGGCGGGGACCAG
AGAGGAGCCTGGCGGGGGTGGCTGGGTGGCTGGGGGAATCCCCCCAACTTCCCATCGCAGGCGCAGCTCTCTCGGCCGCCTATTTCCTCC
GAAACCCGCGCTGCGGAGCAGCCCAGTGCATAGAGTTCAACACTTCCCCTTGTTGTGGAAAGTAAAGGAGCCTCACTACCACCTTTTTTT
CTTTGCGTTTTCTTACTGCTGGTCCTGGGAGCCTTTTCCTTCGGAGCAGCAGCCCTGTCCGGCATCTGTCTTGAGCTCCCAGCAAGGAAA
GTCCATCAGCTTGATAATGGAGGAGAACAATGACTCCACGGAGAACCCCCAACAAGGCCAAGGGCGGCAGAATGCCATCAAGTGTGGGTG
GCTGAGGAAGCAAGGAGGCTTTGTCAAGACTTGGCATACTCGCTGGTTTGTGCTCAAGGGGGATCAGCTCTATTATTTCAAAGATGAAGA
TGAAACCAAGCCCTTGATCCAAGAAATTGACATAAATAATGAGCAAGAAAATGATTATGAAGAGGATATTGCCTCATTTTCCACATATAT
TCCTTCCACACAGAACCCAGCATTTCATCATGAAAGCAGGAAGACATACGGGCAGAGTGCAGATGGAGCTGAGGCAAATGAAATGGAAGG
GGAAGGAAAACAGAATGGATCAGGCATGGAGACCAAACACAGCCCACTAGAGGTTGGCAGTGAGAGTTCTGAAGACCAGTATGATGACTT
GTATGTGTTCATTCCTGGTGCTGATCCAGAAAATAATTCACAAGAGCCACTCATGAGCAGCAGACCTCCTCTCCCCCCGCCGCGACCTGT
AGCTAATGCCTTCCAACTGGAAAGACCTCACTTCACCTTACCAGGGACAATGGTGGAAGGCCAAATGGAAAGAAGTCAAAACTGGGGTCA
TCCTGGTGTTAGACAAGAAACAGGAGATGAACCCAAAGGAGAAAAAGAGAAGAAAGAAGAGGAAAAAGAGCAGGAGGAGGAAGAAGACCC
ATATACTTTTGCTGAGATTGATGACAGTGAATATGACATGATATTGGCCAATCTGAGTATAAAGAAAAAAACTGGGAGTCGGTCTTTCAT
TATAAATAGACCTCCTGCCCCCACACCCCGACCCACAAGTATACCTCCAAAAGAGGAAACTACACCTTACATAGCTCAAGTGTTTCAACA
AAAGACAGCCAGAAGACAATCTGATGATGACAAGTTCTGTGGTCTTCCTAAGAAACAAGACAGAGCTCGGATAGAGAGTCCAGCCTTTTC
TACTCTCAGGGGCTGTCTAACTGATGGTCAGGAAGAACTCATCCTCCTGCAGGAGAAAGTAAAGAATGGGAAAATGTCTATGGATGAAGC
TCTGGAGAAATTTAAACACTGGCAGATGGGAAAAAGTGGCCTGGAAATGATTCAGCAGGAGAAATTACGACAACTACGAGACTGCATTAT
TGGGAAAAGGCCAGAAGAAGAAAATGTCTATAATAAACTCACCATTGTGCACCATCCAGGTGGTAAGGAAACTGCCCACAATGAAAATAA
GTTTTATAATGTACACTTCAGCAATAAGCTTCCTGCTCGACCCCAAGTTGAAAAGGAATTTGGTTTCTGTTGCAAGAAAGATCATTAAAG
AAGGTTATTATAATGAAACTCACGAATCTACGGACATTTTGCTTTCAGGGTGAAGCAAGCTTGAATTTGGATTGCCTGCTCTCTTTAAAG
CGAATTCATACTATGACAGCAGAAACAAAACTTCAGATTTCAGAATTTGTTATTGGCAAAATTTATTCTCATTATACCTGCTTCATATGG
GTATATTACTATTAAAACAGAATACCATAGAGTAATTGCATTATTTGAAAATTCTCTCATTTTACAATGCACTTCACCAATGAAACAGCT
AATTTCCATTTTGAAAATTAAAAGAAAACAGCACAGAGAAGTTAAATGCGGTGTAGCAAAGTTATGGGGTCTGCTTGAGGGCACTAACCT
CAACAGATTATTCCTCCTCTCCTTAGAATAACCATGAAAATACAAATTTACTTAGCACATTTTTGCTTTTTAAGTAGCTGGTTCATTTTC
TGAATTTCTCACATTCAGAGTTCCAGTCATTATTGTTACATCATGTTTGCAGAAACCTTGTCTTATTTAGTGTCTATTTGCATATAACCC
TGAAAACATTATTATTTGAAAACTTTTCTATATCTCAAATTAATATACATTTTCATAACCTACCTTTGTATTAAGACTTGCAATTTTATC
AATCTATTATTTCTTAGAAACAATTTACTAGCTTAGAATAGAAAGCAATGTTATCGTCATATAATTTTCATGTACAAATGCCACAAATAA

>6013_6013_3_ARHGAP24-BANK1_ARHGAP24_chr4_86491874_ENST00000395184_BANK1_chr4_102942670_ENST00000444316_length(amino acids)=505AA_BP=122
MRSSPVHRVQHFPLLWKVKEPHYHLFFFAFSYCWSWEPFPSEQQPCPASVLSSQQGKSISLIMEENNDSTENPQQGQGRQNAIKCGWLRK
QGGFVKTWHTRWFVLKGDQLYYFKDEDETKPLIQEIDINNEQENDYEEDIASFSTYIPSTQNPAFHHESRKTYGQSADGAEANEMEGEGK
QNGSGMETKHSPLEVGSESSEDQYDDLYVFIPGADPENNSQEPLMSSRPPLPPPRPVANAFQLERPHFTLPGTMVEGQMERSQNWGHPGV
RQETGDEPKGEKEKKEEEKEQEEEEDPYTFAEIDDSEYDMILANLSIKKKTGSRSFIINRPPAPTPRPTSIPPKEETTPYIAQVFQQKTA
RRQSDDDKFCGLPKKQDRARIESPAFSTLRGCLTDGQEELILLQEKVKNGKMSMDEALEKFKHWQMGKSGLEMIQQEKLRQLRDCIIGKR

--------------------------------------------------------------
>6013_6013_4_ARHGAP24-BANK1_ARHGAP24_chr4_86491874_ENST00000395184_BANK1_chr4_102942670_ENST00000504592_length(transcript)=2611nt_BP=646nt
TTGTACTGTATATTTACACATTCACACACAATCACCCTTTCTAACTTCTGGGACTCTTTGCGCAACTGCTAGGATTTCTCAAGTGCATGT
GGCAACACAGCCCAGCTCCGGGTGGAAACCAGCAGGGCTCTGGAGGGGCTCGGAGACCAGGGGAGCTGTCAAGGCTGCGGCGGGGACCAG
AGAGGAGCCTGGCGGGGGTGGCTGGGTGGCTGGGGGAATCCCCCCAACTTCCCATCGCAGGCGCAGCTCTCTCGGCCGCCTATTTCCTCC
GAAACCCGCGCTGCGGAGCAGCCCAGTGCATAGAGTTCAACACTTCCCCTTGTTGTGGAAAGTAAAGGAGCCTCACTACCACCTTTTTTT
CTTTGCGTTTTCTTACTGCTGGTCCTGGGAGCCTTTTCCTTCGGAGCAGCAGCCCTGTCCGGCATCTGTCTTGAGCTCCCAGCAAGGAAA
GTCCATCAGCTTGATAATGGAGGAGAACAATGACTCCACGGAGAACCCCCAACAAGGCCAAGGGCGGCAGAATGCCATCAAGTGTGGGTG
GCTGAGGAAGCAAGGAGGCTTTGTCAAGACTTGGCATACTCGCTGGTTTGTGCTCAAGGGGGATCAGCTCTATTATTTCAAAGATGAAGA
TGAAACCAAGCCCTTGATCCAAGAAATTGACATAAATAATGAGCAAGAAAATGATTATGAAGAGGATATTGCCTCATTTTCCACATATAT
TCCTTCCACACAGAACCCAGCATTTCATCATGAAAGCAGGAAGACATACGGGCAGAGTGCAGATGGAGCTGAGGCAAATGAAATGGAAGG
GGAAGGAAAACAGAATGGATCAGGCATGGAGACCAAACACAGCCCACTAGAGGTTGGCAGTGAGAGTTCTGAAGACCAGTATGATGACTT
GTATGTGTTCATTCCTGGTGCTGATCCAGAAAATAATTCACAAGAGCCACTCATGAGCAGCAGACCTCCTCTCCCCCCGCCGCGACCTGT
AGCTAATGCCTTCCAACTGGAAAGACCTCACTTCACCTTACCAGGGACAATGGTGGAAGGCCAAATGGAAAGAAGTCAAAACTGGGGTCA
TCCTGGTGTTAGACAAGAAACAGGAGATGAACCCAAAGGAGAAAAAGAGAAGAAAGAAGAGGAAAAAGAGCAGGAGGAGGAAGAAGACCC
ATATACTTTTGCTGAGATTGATGACAGTGAATATGACATGATATTGGCCAATCTGAGTATAAAGAAAAAAACTGGGAGTCGGTCTTTCAT
TATAAATAGACCTCCTGCCCCCACACCCCGACCCACAAGTATACCTCCAAAAGAGGAAACTACACCTTACATAGCTCAAGTGTTTCAACA
AAAGACAGCCAGAAGACAATCTGATGATGACAAGTTCTGTGGTCTTCCTAAGAAACAAGACAGAGCTCGGATAGAGAGTCCAGCCTTTTC
TACTCTCAGGGGCTGTCTAACTGATGGTCAGGAAGAACTCATCCTCCTGCAGGAGAAAGTAAAGAATGGGAAAATGTCTATGGATGAAGC
TCTGGAGAAATTTAAACACTGGCAGATGGGAAAAAGTGGCCTGGAAATGATTCAGCAGGAGAAATTACGACAACTACGAGACTGCATTAT
TGGGAAAAGGCCAGAAGAAGAAAATGTCTATAATAAACTCACCATTGTGCACCATCCAGGTGGTAAGGAAACTGCCCACAATGAAAATAA
GTTTTATAATGTACACTTCAGCAATAAGCTTCCTGCTCGACCCCAAGTTGAAAAGGAATTTGGTTTCTGTTGCAAGAAAGATCATTAAAG
AAGGTTATTATAATGAAACTCACGAATCTACGGACATTTTGCTTTCAGGGTGAAGCAAGCTTGAATTTGGATTGCCTGCTCTCTTTAAAG
CGAATTCATACTATGACAGCAGAAACAAAACTTCAGATTTCAGAATTTGTTATTGGCAAAATTTATTCTCATTATACCTGCTTCATATGG
GTATATTACTATTAAAACAGAATACCATAGAGTAATTGCATTATTTGAAAATTCTCTCATTTTACAATGCACTTCACCAATGAAACAGCT
AATTTCCATTTTGAAAATTAAAAGAAAACAGCACAGAGAAGTTAAATGCGGTGTAGCAAAGTTATGGGGTCTGCTTGAGGGCACTAACCT
CAACAGATTATTCCTCCTCTCCTTAGAATAACCATGAAAATACAAATTTACTTAGCACATTTTTGCTTTTTAAGTAGCTGGTTCATTTTC
TGAATTTCTCACATTCAGAGTTCCAGTCATTATTGTTACATCATGTTTGCAGAAACCTTGTCTTATTTAGTGTCTATTTGCATATAACCC
TGAAAACATTATTATTTGAAAACTTTTCTATATCTCAAATTAATATACATTTTCATAACCTACCTTTGTATTAAGACTTGCAATTTTATC
AATCTATTATTTCTTAGAAACAATTTACTAGCTTAGAATAGAAAGCAATGTTATCGTCATATAATTTTCATGTACAAATGCCACAAATAA
ATTGAATGTTTAAAGCTATGTCTGAGTTTTTAAAGTAAATTTATAAGAATTAGCCAATAAAATTGCTTCTCGGCCTTTTGGCTAAGATCA

>6013_6013_4_ARHGAP24-BANK1_ARHGAP24_chr4_86491874_ENST00000395184_BANK1_chr4_102942670_ENST00000504592_length(amino acids)=505AA_BP=122
MRSSPVHRVQHFPLLWKVKEPHYHLFFFAFSYCWSWEPFPSEQQPCPASVLSSQQGKSISLIMEENNDSTENPQQGQGRQNAIKCGWLRK
QGGFVKTWHTRWFVLKGDQLYYFKDEDETKPLIQEIDINNEQENDYEEDIASFSTYIPSTQNPAFHHESRKTYGQSADGAEANEMEGEGK
QNGSGMETKHSPLEVGSESSEDQYDDLYVFIPGADPENNSQEPLMSSRPPLPPPRPVANAFQLERPHFTLPGTMVEGQMERSQNWGHPGV
RQETGDEPKGEKEKKEEEKEQEEEEDPYTFAEIDDSEYDMILANLSIKKKTGSRSFIINRPPAPTPRPTSIPPKEETTPYIAQVFQQKTA
RRQSDDDKFCGLPKKQDRARIESPAFSTLRGCLTDGQEELILLQEKVKNGKMSMDEALEKFKHWQMGKSGLEMIQQEKLRQLRDCIIGKR

--------------------------------------------------------------
>6013_6013_5_ARHGAP24-BANK1_ARHGAP24_chr4_86491874_ENST00000395184_BANK1_chr4_102942670_ENST00000508653_length(transcript)=1803nt_BP=646nt
TTGTACTGTATATTTACACATTCACACACAATCACCCTTTCTAACTTCTGGGACTCTTTGCGCAACTGCTAGGATTTCTCAAGTGCATGT
GGCAACACAGCCCAGCTCCGGGTGGAAACCAGCAGGGCTCTGGAGGGGCTCGGAGACCAGGGGAGCTGTCAAGGCTGCGGCGGGGACCAG
AGAGGAGCCTGGCGGGGGTGGCTGGGTGGCTGGGGGAATCCCCCCAACTTCCCATCGCAGGCGCAGCTCTCTCGGCCGCCTATTTCCTCC
GAAACCCGCGCTGCGGAGCAGCCCAGTGCATAGAGTTCAACACTTCCCCTTGTTGTGGAAAGTAAAGGAGCCTCACTACCACCTTTTTTT
CTTTGCGTTTTCTTACTGCTGGTCCTGGGAGCCTTTTCCTTCGGAGCAGCAGCCCTGTCCGGCATCTGTCTTGAGCTCCCAGCAAGGAAA
GTCCATCAGCTTGATAATGGAGGAGAACAATGACTCCACGGAGAACCCCCAACAAGGCCAAGGGCGGCAGAATGCCATCAAGTGTGGGTG
GCTGAGGAAGCAAGGAGGCTTTGTCAAGACTTGGCATACTCGCTGGTTTGTGCTCAAGGGGGATCAGCTCTATTATTTCAAAGATGAAGA
TGAAACCAAGCCCTTGATCCAAGAAATTGACATAAATAATGAGCAAGAAAATGATTATGAAGAGGATATTGCCTCATTTTCCACATATAT
TCCTTCCACACAGAACCCAGCATTTCATCATGAAAGCAGGAAGACATACGGGCAGAGTGCAGATGGAGCTGAGGCAAATGAAATGGAAGG
GGAAGGAAAACAGAATGGATCAGGCATGGAGACCAAACACAGCCCACTAGAGGTTGGCAGTGAGAGTTCTGAAGACCAGTATGATGACTT
GTATGTGTTCATTCCTGGTGCTGATCCAGAAAATAATTCACAAGAGCCACTCATGAGCAGCAGACCTCCTCTCCCCCCGCCGCGACCTGT
AGCTAATGCCTTCCAACTGGAAAGACCTCACTTCACCTTACCAGGGACAATGGTGGAAGGCCAAATGGAAAGAAGTCAAAACTGGGGTCA
TCCTGGTGTTAGACAAGAAACAGGAGATGAACCCAAAGGAGAAAAAGAGAAGAAAGAAGAGGAAAAAGAGCAGGAGGAGGAAGAAGACCC
ATATACTTTTGCTGAGATTGATGACAGTGAATATGACATGATATTGGCCAATCTGAGTATAAAGAAAAAAACTGGGAGTCGGTCTTTCAT
TATAAATAGACCTCCTGCCCCCACACCCCGACCCACAAGTATACCTCCAAAAGAGGAAACTACACCTTACATAGCTCAAGTGTTTCAACA
AAAGACAGCCAGAAGACAATCTGATGATGACAAGTTCTGTGGTCTTCCTAAGAAACAAGACAGAGCTCGGATAGAGAGTCCAGCCTTTTC
TACTCTCAGGGGCTGTCTAACTGATGGTCAGGAAGAACTCATCCTCCTGCAGGAGAAAGTAAAGAATGGGAAAATGTCTATGGATGAAGC
TCTGGAGAAATTTAAACACTGGCAGATGGGAAAAAGTGGCCTGGAAATGATTCAGCAGGAGAAATTACGACAACTACGAGACTGCATTAT
TGGGAAAAGGCCAGAAGAAGAAAATGTCTATAATAAACTCACCATTGTGCACCATCCAGGTGGTAAGGAAACTGCCCACAATGAAAATAA
GTTTTATAATGTACACTTCAGCAATAAGCTTCCTGCTCGACCCCAAGTTGAAAAGGAATTTGGTTTCTGTTGCAAGAAAGATCATTAAAG

>6013_6013_5_ARHGAP24-BANK1_ARHGAP24_chr4_86491874_ENST00000395184_BANK1_chr4_102942670_ENST00000508653_length(amino acids)=505AA_BP=122
MRSSPVHRVQHFPLLWKVKEPHYHLFFFAFSYCWSWEPFPSEQQPCPASVLSSQQGKSISLIMEENNDSTENPQQGQGRQNAIKCGWLRK
QGGFVKTWHTRWFVLKGDQLYYFKDEDETKPLIQEIDINNEQENDYEEDIASFSTYIPSTQNPAFHHESRKTYGQSADGAEANEMEGEGK
QNGSGMETKHSPLEVGSESSEDQYDDLYVFIPGADPENNSQEPLMSSRPPLPPPRPVANAFQLERPHFTLPGTMVEGQMERSQNWGHPGV
RQETGDEPKGEKEKKEEEKEQEEEEDPYTFAEIDDSEYDMILANLSIKKKTGSRSFIINRPPAPTPRPTSIPPKEETTPYIAQVFQQKTA
RRQSDDDKFCGLPKKQDRARIESPAFSTLRGCLTDGQEELILLQEKVKNGKMSMDEALEKFKHWQMGKSGLEMIQQEKLRQLRDCIIGKR

--------------------------------------------------------------
>6013_6013_6_ARHGAP24-BANK1_ARHGAP24_chr4_86491874_ENST00000503995_BANK1_chr4_102942670_ENST00000322953_length(transcript)=2414nt_BP=522nt
GGGCTCTGGAGGGGCTCGGAGACCAGGGGAGCTGTCAAGGCTGCGGCGGGGACCAGAGAGGAGCCTGGCGGGGGTGGCTGGGTGGCTGGG
GGAATCCCCCCAACTTCCCATCGCAGGCGCAGCTCTCTCGGCCGCCTATTTCCTCCGAAACCCGCGCTGCGGAGCAGCCCAGTGCATAGA
GTTCAACACTTCCCCTTGTTGTGGAAAGTAAAGGAGCCTCACTACCACCTTTTTTTCTTTGCGTTTTCTTACTGCTGGTCCTGGGAGCCT
TTTCCTTCGGAGCAGCAGCCCTGTCCGGCATCTGTCTTGAGCTCCCAGCAAGGAAAGTCCATCAGCTTGATAATGGAGGAGAACAATGAC
TCCACGGAGAACCCCCAACAAGGCCAAGGGCGGCAGAATGCCATCAAGTGTGGGTGGCTGAGGAAGCAAGGAGGCTTTGTCAAGACTTGG
CATACTCGCTGGTTTGTGCTCAAGGGGGATCAGCTCTATTATTTCAAAGATGAAGATGAAACCAAGCCCTTGATCCAAGAAATTGACATA
AATAATGAGCAAGAAAATGATTATGAAGAGGATATTGCCTCATTTTCCACATATATTCCTTCCACACAGAACCCAGCATTTCATCATGAA
AGCAGGAAGACATACGGGCAGAGTGCAGATGGAGCTGAGGCAAATGAAATGGAAGGGGAAGGAAAACAGAATGGATCAGGCATGGAGACC
AAACACAGCCCACTAGAGGTTGGCAGTGAGAGTTCTGAAGACCAGTATGATGACTTGTATGTGTTCATTCCTGGTGCTGATCCAGAAAAT
AATTCACAAGAGCCACTCATGAGCAGCAGACCTCCTCTCCCCCCGCCGCGACCTGTAGCTAATGCCTTCCAACTGGAAAGACCTCACTTC
ACCTTACCAGGGACAATGGTGGAAGGCCAAATGGAAAGAAGTCAAAACTGGGGTCATCCTGGTGTTAGACAAGAAACAGGAGATGAACCC
AAAGGAGAAAAAGAGAAGAAAGAAGAGGAAAAAGAGCAGGAGGAGGAAGAAGACCCATATACTTTTGCTGAGATTGATGACAGTGAATAT
GACATGATATTGGCCAATCTGAGTATAAAGAAAAAAACTGGGAGTCGGTCTTTCATTATAAATAGACCTCCTGCCCCCACACCCCGACCC
ACAAGTATACCTCCAAAAGAGGAAACTACACCTTACATAGCTCAAGTGTTTCAACAAAAGACAGCCAGAAGACAATCTGATGATGACAAG
TTCTGTGGTCTTCCTAAGAAACAAGACAGAGCTCGGATAGAGAGTCCAGCCTTTTCTACTCTCAGGGGCTGTCTAACTGATGGTCAGGAA
GAACTCATCCTCCTGCAGGAGAAAGTAAAGAATGGGAAAATGTCTATGGATGAAGCTCTGGAGAAATTTAAACACTGGCAGATGGGAAAA
AGTGGCCTGGAAATGATTCAGCAGGAGAAATTACGACAACTACGAGACTGCATTATTGGGAAAAGGCCAGAAGAAGAAAATGTCTATAAT
AAACTCACCATTGTGCACCATCCAGGTGGTAAGGAAACTGCCCACAATGAAAATAAGTTTTATAATGTACACTTCAGCAATAAGCTTCCT
GCTCGACCCCAAGTTGAAAAGGAATTTGGTTTCTGTTGCAAGAAAGATCATTAAAGAAGGTTATTATAATGAAACTCACGAATCTACGGA
CATTTTGCTTTCAGGGTGAAGCAAGCTTGAATTTGGATTGCCTGCTCTCTTTAAAGCGAATTCATACTATGACAGCAGAAACAAAACTTC
AGATTTCAGAATTTGTTATTGGCAAAATTTATTCTCATTATACCTGCTTCATATGGGTATATTACTATTAAAACAGAATACCATAGAGTA
ATTGCATTATTTGAAAATTCTCTCATTTTACAATGCACTTCACCAATGAAACAGCTAATTTCCATTTTGAAAATTAAAAGAAAACAGCAC
AGAGAAGTTAAATGCGGTGTAGCAAAGTTATGGGGTCTGCTTGAGGGCACTAACCTCAACAGATTATTCCTCCTCTCCTTAGAATAACCA
TGAAAATACAAATTTACTTAGCACATTTTTGCTTTTTAAGTAGCTGGTTCATTTTCTGAATTTCTCACATTCAGAGTTCCAGTCATTATT
GTTACATCATGTTTGCAGAAACCTTGTCTTATTTAGTGTCTATTTGCATATAACCCTGAAAACATTATTATTTGAAAACTTTTCTATATC
TCAAATTAATATACATTTTCATAACCTACCTTTGTATTAAGACTTGCAATTTTATCAATCTATTATTTCTTAGAAACAATTTACTAGCTT

>6013_6013_6_ARHGAP24-BANK1_ARHGAP24_chr4_86491874_ENST00000503995_BANK1_chr4_102942670_ENST00000322953_length(amino acids)=505AA_BP=122
MRSSPVHRVQHFPLLWKVKEPHYHLFFFAFSYCWSWEPFPSEQQPCPASVLSSQQGKSISLIMEENNDSTENPQQGQGRQNAIKCGWLRK
QGGFVKTWHTRWFVLKGDQLYYFKDEDETKPLIQEIDINNEQENDYEEDIASFSTYIPSTQNPAFHHESRKTYGQSADGAEANEMEGEGK
QNGSGMETKHSPLEVGSESSEDQYDDLYVFIPGADPENNSQEPLMSSRPPLPPPRPVANAFQLERPHFTLPGTMVEGQMERSQNWGHPGV
RQETGDEPKGEKEKKEEEKEQEEEEDPYTFAEIDDSEYDMILANLSIKKKTGSRSFIINRPPAPTPRPTSIPPKEETTPYIAQVFQQKTA
RRQSDDDKFCGLPKKQDRARIESPAFSTLRGCLTDGQEELILLQEKVKNGKMSMDEALEKFKHWQMGKSGLEMIQQEKLRQLRDCIIGKR

--------------------------------------------------------------
>6013_6013_7_ARHGAP24-BANK1_ARHGAP24_chr4_86491874_ENST00000503995_BANK1_chr4_102942670_ENST00000428908_length(transcript)=2485nt_BP=522nt
GGGCTCTGGAGGGGCTCGGAGACCAGGGGAGCTGTCAAGGCTGCGGCGGGGACCAGAGAGGAGCCTGGCGGGGGTGGCTGGGTGGCTGGG
GGAATCCCCCCAACTTCCCATCGCAGGCGCAGCTCTCTCGGCCGCCTATTTCCTCCGAAACCCGCGCTGCGGAGCAGCCCAGTGCATAGA
GTTCAACACTTCCCCTTGTTGTGGAAAGTAAAGGAGCCTCACTACCACCTTTTTTTCTTTGCGTTTTCTTACTGCTGGTCCTGGGAGCCT
TTTCCTTCGGAGCAGCAGCCCTGTCCGGCATCTGTCTTGAGCTCCCAGCAAGGAAAGTCCATCAGCTTGATAATGGAGGAGAACAATGAC
TCCACGGAGAACCCCCAACAAGGCCAAGGGCGGCAGAATGCCATCAAGTGTGGGTGGCTGAGGAAGCAAGGAGGCTTTGTCAAGACTTGG
CATACTCGCTGGTTTGTGCTCAAGGGGGATCAGCTCTATTATTTCAAAGATGAAGATGAAACCAAGCCCTTGATCCAAGAAATTGACATA
AATAATGAGCAAGAAAATGATTATGAAGAGGATATTGCCTCATTTTCCACATATATTCCTTCCACACAGAACCCAGCATTTCATCATGAA
AGCAGGAAGACATACGGGCAGAGTGCAGATGGAGCTGAGGCAAATGAAATGGAAGGGGAAGGAAAACAGAATGGATCAGGCATGGAGACC
AAACACAGCCCACTAGAGGTTGGCAGTGAGAGTTCTGAAGACCAGTATGATGACTTGTATGTGTTCATTCCTGGTGCTGATCCAGAAAAT
AATTCACAAGAGCCACTCATGAGCAGCAGACCTCCTCTCCCCCCGCCGCGACCTGTAGCTAATGCCTTCCAACTGGAAAGACCTCACTTC
ACCTTACCAGGGACAATGGTGGAAGGCCAAATGGAAAGAAGTCAAAACTGGGGTCATCCTGGTGTTAGACAAGAAACAGGAGATGAACCC
AAAGGAGAAAAAGAGAAGAAAGAAGAGGAAAAAGAGCAGGAGGAGGAAGAAGACCCATATACTTTTGCTGAGATTGATGACAGTGAATAT
GACATGATATTGGCCAATCTGAGTATAAAGAAAAAAACTGGGAGTCGGTCTTTCATTATAAATAGACCTCCTGCCCCCACACCCCGACCC
ACAAGTATACCTCCAAAAGAGGAAACTACACCTTACATAGCTCAAGTGTTTCAACAAAAGACAGCCAGAAGACAATCTGATGATGACAAG
TTCTGTGGTCTTCCTAAGAAACAAGACAGAGCTCGGATAGAGAGTCCAGCCTTTTCTACTCTCAGGGGCTGTCTAACTGATGGTCAGGAA
GAACTCATCCTCCTGCAGGAGAAAGTAAAGAATGGGAAAATGTCTATGGATGAAGCTCTGGAGAAATTTAAACACTGGCAGATGGGAAAA
AGTGGCCTGGAAATGATTCAGCAGGAGAAATTACGACAACTACGAGACTGCATTATTGGGAAAAGGCCAGAAGAAGAAAATGTCTATAAT
AAACTCACCATTGTGCACCATCCAGGTGGTAAGGAAACTGCCCACAATGAAAATAAGTTTTATAATGTACACTTCAGCAATAAGCTTCCT
GCTCGACCCCAAGTTGAAAAGGAATTTGGTTTCTGTTGCAAGAAAGATCATTAAAGAAGGTTATTATAATGAAACTCACGAATCTACGGA
CATTTTGCTTTCAGGGTGAAGCAAGCTTGAATTTGGATTGCCTGCTCTCTTTAAAGCGAATTCATACTATGACAGCAGAAACAAAACTTC
AGATTTCAGAATTTGTTATTGGCAAAATTTATTCTCATTATACCTGCTTCATATGGGTATATTACTATTAAAACAGAATACCATAGAGTA
ATTGCATTATTTGAAAATTCTCTCATTTTACAATGCACTTCACCAATGAAACAGCTAATTTCCATTTTGAAAATTAAAAGAAAACAGCAC
AGAGAAGTTAAATGCGGTGTAGCAAAGTTATGGGGTCTGCTTGAGGGCACTAACCTCAACAGATTATTCCTCCTCTCCTTAGAATAACCA
TGAAAATACAAATTTACTTAGCACATTTTTGCTTTTTAAGTAGCTGGTTCATTTTCTGAATTTCTCACATTCAGAGTTCCAGTCATTATT
GTTACATCATGTTTGCAGAAACCTTGTCTTATTTAGTGTCTATTTGCATATAACCCTGAAAACATTATTATTTGAAAACTTTTCTATATC
TCAAATTAATATACATTTTCATAACCTACCTTTGTATTAAGACTTGCAATTTTATCAATCTATTATTTCTTAGAAACAATTTACTAGCTT
AGAATAGAAAGCAATGTTATCGTCATATAATTTTCATGTACAAATGCCACAAATAAATTGAATGTTTAAAGCTATGTCTGAGTTTTTAAA

>6013_6013_7_ARHGAP24-BANK1_ARHGAP24_chr4_86491874_ENST00000503995_BANK1_chr4_102942670_ENST00000428908_length(amino acids)=505AA_BP=122
MRSSPVHRVQHFPLLWKVKEPHYHLFFFAFSYCWSWEPFPSEQQPCPASVLSSQQGKSISLIMEENNDSTENPQQGQGRQNAIKCGWLRK
QGGFVKTWHTRWFVLKGDQLYYFKDEDETKPLIQEIDINNEQENDYEEDIASFSTYIPSTQNPAFHHESRKTYGQSADGAEANEMEGEGK
QNGSGMETKHSPLEVGSESSEDQYDDLYVFIPGADPENNSQEPLMSSRPPLPPPRPVANAFQLERPHFTLPGTMVEGQMERSQNWGHPGV
RQETGDEPKGEKEKKEEEKEQEEEEDPYTFAEIDDSEYDMILANLSIKKKTGSRSFIINRPPAPTPRPTSIPPKEETTPYIAQVFQQKTA
RRQSDDDKFCGLPKKQDRARIESPAFSTLRGCLTDGQEELILLQEKVKNGKMSMDEALEKFKHWQMGKSGLEMIQQEKLRQLRDCIIGKR

--------------------------------------------------------------
>6013_6013_8_ARHGAP24-BANK1_ARHGAP24_chr4_86491874_ENST00000503995_BANK1_chr4_102942670_ENST00000444316_length(transcript)=2414nt_BP=522nt
GGGCTCTGGAGGGGCTCGGAGACCAGGGGAGCTGTCAAGGCTGCGGCGGGGACCAGAGAGGAGCCTGGCGGGGGTGGCTGGGTGGCTGGG
GGAATCCCCCCAACTTCCCATCGCAGGCGCAGCTCTCTCGGCCGCCTATTTCCTCCGAAACCCGCGCTGCGGAGCAGCCCAGTGCATAGA
GTTCAACACTTCCCCTTGTTGTGGAAAGTAAAGGAGCCTCACTACCACCTTTTTTTCTTTGCGTTTTCTTACTGCTGGTCCTGGGAGCCT
TTTCCTTCGGAGCAGCAGCCCTGTCCGGCATCTGTCTTGAGCTCCCAGCAAGGAAAGTCCATCAGCTTGATAATGGAGGAGAACAATGAC
TCCACGGAGAACCCCCAACAAGGCCAAGGGCGGCAGAATGCCATCAAGTGTGGGTGGCTGAGGAAGCAAGGAGGCTTTGTCAAGACTTGG
CATACTCGCTGGTTTGTGCTCAAGGGGGATCAGCTCTATTATTTCAAAGATGAAGATGAAACCAAGCCCTTGATCCAAGAAATTGACATA
AATAATGAGCAAGAAAATGATTATGAAGAGGATATTGCCTCATTTTCCACATATATTCCTTCCACACAGAACCCAGCATTTCATCATGAA
AGCAGGAAGACATACGGGCAGAGTGCAGATGGAGCTGAGGCAAATGAAATGGAAGGGGAAGGAAAACAGAATGGATCAGGCATGGAGACC
AAACACAGCCCACTAGAGGTTGGCAGTGAGAGTTCTGAAGACCAGTATGATGACTTGTATGTGTTCATTCCTGGTGCTGATCCAGAAAAT
AATTCACAAGAGCCACTCATGAGCAGCAGACCTCCTCTCCCCCCGCCGCGACCTGTAGCTAATGCCTTCCAACTGGAAAGACCTCACTTC
ACCTTACCAGGGACAATGGTGGAAGGCCAAATGGAAAGAAGTCAAAACTGGGGTCATCCTGGTGTTAGACAAGAAACAGGAGATGAACCC
AAAGGAGAAAAAGAGAAGAAAGAAGAGGAAAAAGAGCAGGAGGAGGAAGAAGACCCATATACTTTTGCTGAGATTGATGACAGTGAATAT
GACATGATATTGGCCAATCTGAGTATAAAGAAAAAAACTGGGAGTCGGTCTTTCATTATAAATAGACCTCCTGCCCCCACACCCCGACCC
ACAAGTATACCTCCAAAAGAGGAAACTACACCTTACATAGCTCAAGTGTTTCAACAAAAGACAGCCAGAAGACAATCTGATGATGACAAG
TTCTGTGGTCTTCCTAAGAAACAAGACAGAGCTCGGATAGAGAGTCCAGCCTTTTCTACTCTCAGGGGCTGTCTAACTGATGGTCAGGAA
GAACTCATCCTCCTGCAGGAGAAAGTAAAGAATGGGAAAATGTCTATGGATGAAGCTCTGGAGAAATTTAAACACTGGCAGATGGGAAAA
AGTGGCCTGGAAATGATTCAGCAGGAGAAATTACGACAACTACGAGACTGCATTATTGGGAAAAGGCCAGAAGAAGAAAATGTCTATAAT
AAACTCACCATTGTGCACCATCCAGGTGGTAAGGAAACTGCCCACAATGAAAATAAGTTTTATAATGTACACTTCAGCAATAAGCTTCCT
GCTCGACCCCAAGTTGAAAAGGAATTTGGTTTCTGTTGCAAGAAAGATCATTAAAGAAGGTTATTATAATGAAACTCACGAATCTACGGA
CATTTTGCTTTCAGGGTGAAGCAAGCTTGAATTTGGATTGCCTGCTCTCTTTAAAGCGAATTCATACTATGACAGCAGAAACAAAACTTC
AGATTTCAGAATTTGTTATTGGCAAAATTTATTCTCATTATACCTGCTTCATATGGGTATATTACTATTAAAACAGAATACCATAGAGTA
ATTGCATTATTTGAAAATTCTCTCATTTTACAATGCACTTCACCAATGAAACAGCTAATTTCCATTTTGAAAATTAAAAGAAAACAGCAC
AGAGAAGTTAAATGCGGTGTAGCAAAGTTATGGGGTCTGCTTGAGGGCACTAACCTCAACAGATTATTCCTCCTCTCCTTAGAATAACCA
TGAAAATACAAATTTACTTAGCACATTTTTGCTTTTTAAGTAGCTGGTTCATTTTCTGAATTTCTCACATTCAGAGTTCCAGTCATTATT
GTTACATCATGTTTGCAGAAACCTTGTCTTATTTAGTGTCTATTTGCATATAACCCTGAAAACATTATTATTTGAAAACTTTTCTATATC
TCAAATTAATATACATTTTCATAACCTACCTTTGTATTAAGACTTGCAATTTTATCAATCTATTATTTCTTAGAAACAATTTACTAGCTT

>6013_6013_8_ARHGAP24-BANK1_ARHGAP24_chr4_86491874_ENST00000503995_BANK1_chr4_102942670_ENST00000444316_length(amino acids)=505AA_BP=122
MRSSPVHRVQHFPLLWKVKEPHYHLFFFAFSYCWSWEPFPSEQQPCPASVLSSQQGKSISLIMEENNDSTENPQQGQGRQNAIKCGWLRK
QGGFVKTWHTRWFVLKGDQLYYFKDEDETKPLIQEIDINNEQENDYEEDIASFSTYIPSTQNPAFHHESRKTYGQSADGAEANEMEGEGK
QNGSGMETKHSPLEVGSESSEDQYDDLYVFIPGADPENNSQEPLMSSRPPLPPPRPVANAFQLERPHFTLPGTMVEGQMERSQNWGHPGV
RQETGDEPKGEKEKKEEEKEQEEEEDPYTFAEIDDSEYDMILANLSIKKKTGSRSFIINRPPAPTPRPTSIPPKEETTPYIAQVFQQKTA
RRQSDDDKFCGLPKKQDRARIESPAFSTLRGCLTDGQEELILLQEKVKNGKMSMDEALEKFKHWQMGKSGLEMIQQEKLRQLRDCIIGKR

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>6013_6013_9_ARHGAP24-BANK1_ARHGAP24_chr4_86491874_ENST00000503995_BANK1_chr4_102942670_ENST00000504592_length(transcript)=2487nt_BP=522nt
GGGCTCTGGAGGGGCTCGGAGACCAGGGGAGCTGTCAAGGCTGCGGCGGGGACCAGAGAGGAGCCTGGCGGGGGTGGCTGGGTGGCTGGG
GGAATCCCCCCAACTTCCCATCGCAGGCGCAGCTCTCTCGGCCGCCTATTTCCTCCGAAACCCGCGCTGCGGAGCAGCCCAGTGCATAGA
GTTCAACACTTCCCCTTGTTGTGGAAAGTAAAGGAGCCTCACTACCACCTTTTTTTCTTTGCGTTTTCTTACTGCTGGTCCTGGGAGCCT
TTTCCTTCGGAGCAGCAGCCCTGTCCGGCATCTGTCTTGAGCTCCCAGCAAGGAAAGTCCATCAGCTTGATAATGGAGGAGAACAATGAC
TCCACGGAGAACCCCCAACAAGGCCAAGGGCGGCAGAATGCCATCAAGTGTGGGTGGCTGAGGAAGCAAGGAGGCTTTGTCAAGACTTGG
CATACTCGCTGGTTTGTGCTCAAGGGGGATCAGCTCTATTATTTCAAAGATGAAGATGAAACCAAGCCCTTGATCCAAGAAATTGACATA
AATAATGAGCAAGAAAATGATTATGAAGAGGATATTGCCTCATTTTCCACATATATTCCTTCCACACAGAACCCAGCATTTCATCATGAA
AGCAGGAAGACATACGGGCAGAGTGCAGATGGAGCTGAGGCAAATGAAATGGAAGGGGAAGGAAAACAGAATGGATCAGGCATGGAGACC
AAACACAGCCCACTAGAGGTTGGCAGTGAGAGTTCTGAAGACCAGTATGATGACTTGTATGTGTTCATTCCTGGTGCTGATCCAGAAAAT
AATTCACAAGAGCCACTCATGAGCAGCAGACCTCCTCTCCCCCCGCCGCGACCTGTAGCTAATGCCTTCCAACTGGAAAGACCTCACTTC
ACCTTACCAGGGACAATGGTGGAAGGCCAAATGGAAAGAAGTCAAAACTGGGGTCATCCTGGTGTTAGACAAGAAACAGGAGATGAACCC
AAAGGAGAAAAAGAGAAGAAAGAAGAGGAAAAAGAGCAGGAGGAGGAAGAAGACCCATATACTTTTGCTGAGATTGATGACAGTGAATAT
GACATGATATTGGCCAATCTGAGTATAAAGAAAAAAACTGGGAGTCGGTCTTTCATTATAAATAGACCTCCTGCCCCCACACCCCGACCC
ACAAGTATACCTCCAAAAGAGGAAACTACACCTTACATAGCTCAAGTGTTTCAACAAAAGACAGCCAGAAGACAATCTGATGATGACAAG
TTCTGTGGTCTTCCTAAGAAACAAGACAGAGCTCGGATAGAGAGTCCAGCCTTTTCTACTCTCAGGGGCTGTCTAACTGATGGTCAGGAA
GAACTCATCCTCCTGCAGGAGAAAGTAAAGAATGGGAAAATGTCTATGGATGAAGCTCTGGAGAAATTTAAACACTGGCAGATGGGAAAA
AGTGGCCTGGAAATGATTCAGCAGGAGAAATTACGACAACTACGAGACTGCATTATTGGGAAAAGGCCAGAAGAAGAAAATGTCTATAAT
AAACTCACCATTGTGCACCATCCAGGTGGTAAGGAAACTGCCCACAATGAAAATAAGTTTTATAATGTACACTTCAGCAATAAGCTTCCT
GCTCGACCCCAAGTTGAAAAGGAATTTGGTTTCTGTTGCAAGAAAGATCATTAAAGAAGGTTATTATAATGAAACTCACGAATCTACGGA
CATTTTGCTTTCAGGGTGAAGCAAGCTTGAATTTGGATTGCCTGCTCTCTTTAAAGCGAATTCATACTATGACAGCAGAAACAAAACTTC
AGATTTCAGAATTTGTTATTGGCAAAATTTATTCTCATTATACCTGCTTCATATGGGTATATTACTATTAAAACAGAATACCATAGAGTA
ATTGCATTATTTGAAAATTCTCTCATTTTACAATGCACTTCACCAATGAAACAGCTAATTTCCATTTTGAAAATTAAAAGAAAACAGCAC
AGAGAAGTTAAATGCGGTGTAGCAAAGTTATGGGGTCTGCTTGAGGGCACTAACCTCAACAGATTATTCCTCCTCTCCTTAGAATAACCA
TGAAAATACAAATTTACTTAGCACATTTTTGCTTTTTAAGTAGCTGGTTCATTTTCTGAATTTCTCACATTCAGAGTTCCAGTCATTATT
GTTACATCATGTTTGCAGAAACCTTGTCTTATTTAGTGTCTATTTGCATATAACCCTGAAAACATTATTATTTGAAAACTTTTCTATATC
TCAAATTAATATACATTTTCATAACCTACCTTTGTATTAAGACTTGCAATTTTATCAATCTATTATTTCTTAGAAACAATTTACTAGCTT
AGAATAGAAAGCAATGTTATCGTCATATAATTTTCATGTACAAATGCCACAAATAAATTGAATGTTTAAAGCTATGTCTGAGTTTTTAAA

>6013_6013_9_ARHGAP24-BANK1_ARHGAP24_chr4_86491874_ENST00000503995_BANK1_chr4_102942670_ENST00000504592_length(amino acids)=505AA_BP=122
MRSSPVHRVQHFPLLWKVKEPHYHLFFFAFSYCWSWEPFPSEQQPCPASVLSSQQGKSISLIMEENNDSTENPQQGQGRQNAIKCGWLRK
QGGFVKTWHTRWFVLKGDQLYYFKDEDETKPLIQEIDINNEQENDYEEDIASFSTYIPSTQNPAFHHESRKTYGQSADGAEANEMEGEGK
QNGSGMETKHSPLEVGSESSEDQYDDLYVFIPGADPENNSQEPLMSSRPPLPPPRPVANAFQLERPHFTLPGTMVEGQMERSQNWGHPGV
RQETGDEPKGEKEKKEEEKEQEEEEDPYTFAEIDDSEYDMILANLSIKKKTGSRSFIINRPPAPTPRPTSIPPKEETTPYIAQVFQQKTA
RRQSDDDKFCGLPKKQDRARIESPAFSTLRGCLTDGQEELILLQEKVKNGKMSMDEALEKFKHWQMGKSGLEMIQQEKLRQLRDCIIGKR

--------------------------------------------------------------
>6013_6013_10_ARHGAP24-BANK1_ARHGAP24_chr4_86491874_ENST00000503995_BANK1_chr4_102942670_ENST00000508653_length(transcript)=1679nt_BP=522nt
GGGCTCTGGAGGGGCTCGGAGACCAGGGGAGCTGTCAAGGCTGCGGCGGGGACCAGAGAGGAGCCTGGCGGGGGTGGCTGGGTGGCTGGG
GGAATCCCCCCAACTTCCCATCGCAGGCGCAGCTCTCTCGGCCGCCTATTTCCTCCGAAACCCGCGCTGCGGAGCAGCCCAGTGCATAGA
GTTCAACACTTCCCCTTGTTGTGGAAAGTAAAGGAGCCTCACTACCACCTTTTTTTCTTTGCGTTTTCTTACTGCTGGTCCTGGGAGCCT
TTTCCTTCGGAGCAGCAGCCCTGTCCGGCATCTGTCTTGAGCTCCCAGCAAGGAAAGTCCATCAGCTTGATAATGGAGGAGAACAATGAC
TCCACGGAGAACCCCCAACAAGGCCAAGGGCGGCAGAATGCCATCAAGTGTGGGTGGCTGAGGAAGCAAGGAGGCTTTGTCAAGACTTGG
CATACTCGCTGGTTTGTGCTCAAGGGGGATCAGCTCTATTATTTCAAAGATGAAGATGAAACCAAGCCCTTGATCCAAGAAATTGACATA
AATAATGAGCAAGAAAATGATTATGAAGAGGATATTGCCTCATTTTCCACATATATTCCTTCCACACAGAACCCAGCATTTCATCATGAA
AGCAGGAAGACATACGGGCAGAGTGCAGATGGAGCTGAGGCAAATGAAATGGAAGGGGAAGGAAAACAGAATGGATCAGGCATGGAGACC
AAACACAGCCCACTAGAGGTTGGCAGTGAGAGTTCTGAAGACCAGTATGATGACTTGTATGTGTTCATTCCTGGTGCTGATCCAGAAAAT
AATTCACAAGAGCCACTCATGAGCAGCAGACCTCCTCTCCCCCCGCCGCGACCTGTAGCTAATGCCTTCCAACTGGAAAGACCTCACTTC
ACCTTACCAGGGACAATGGTGGAAGGCCAAATGGAAAGAAGTCAAAACTGGGGTCATCCTGGTGTTAGACAAGAAACAGGAGATGAACCC
AAAGGAGAAAAAGAGAAGAAAGAAGAGGAAAAAGAGCAGGAGGAGGAAGAAGACCCATATACTTTTGCTGAGATTGATGACAGTGAATAT
GACATGATATTGGCCAATCTGAGTATAAAGAAAAAAACTGGGAGTCGGTCTTTCATTATAAATAGACCTCCTGCCCCCACACCCCGACCC
ACAAGTATACCTCCAAAAGAGGAAACTACACCTTACATAGCTCAAGTGTTTCAACAAAAGACAGCCAGAAGACAATCTGATGATGACAAG
TTCTGTGGTCTTCCTAAGAAACAAGACAGAGCTCGGATAGAGAGTCCAGCCTTTTCTACTCTCAGGGGCTGTCTAACTGATGGTCAGGAA
GAACTCATCCTCCTGCAGGAGAAAGTAAAGAATGGGAAAATGTCTATGGATGAAGCTCTGGAGAAATTTAAACACTGGCAGATGGGAAAA
AGTGGCCTGGAAATGATTCAGCAGGAGAAATTACGACAACTACGAGACTGCATTATTGGGAAAAGGCCAGAAGAAGAAAATGTCTATAAT
AAACTCACCATTGTGCACCATCCAGGTGGTAAGGAAACTGCCCACAATGAAAATAAGTTTTATAATGTACACTTCAGCAATAAGCTTCCT

>6013_6013_10_ARHGAP24-BANK1_ARHGAP24_chr4_86491874_ENST00000503995_BANK1_chr4_102942670_ENST00000508653_length(amino acids)=505AA_BP=122
MRSSPVHRVQHFPLLWKVKEPHYHLFFFAFSYCWSWEPFPSEQQPCPASVLSSQQGKSISLIMEENNDSTENPQQGQGRQNAIKCGWLRK
QGGFVKTWHTRWFVLKGDQLYYFKDEDETKPLIQEIDINNEQENDYEEDIASFSTYIPSTQNPAFHHESRKTYGQSADGAEANEMEGEGK
QNGSGMETKHSPLEVGSESSEDQYDDLYVFIPGADPENNSQEPLMSSRPPLPPPRPVANAFQLERPHFTLPGTMVEGQMERSQNWGHPGV
RQETGDEPKGEKEKKEEEKEQEEEEDPYTFAEIDDSEYDMILANLSIKKKTGSRSFIINRPPAPTPRPTSIPPKEETTPYIAQVFQQKTA
RRQSDDDKFCGLPKKQDRARIESPAFSTLRGCLTDGQEELILLQEKVKNGKMSMDEALEKFKHWQMGKSGLEMIQQEKLRQLRDCIIGKR

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ARHGAP24-BANK1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneBANK1chr4:86491874chr4:102942670ENST000003229536171_154402.0916.3333333333334ITPR2
TgeneBANK1chr4:86491874chr4:102942670ENST000004289085161_154269.0807.0ITPR2
TgeneBANK1chr4:86491874chr4:102942670ENST000004443166171_154372.0963.3333333333334ITPR2
TgeneBANK1chr4:86491874chr4:102942670ENST0000050459210211_154387.0994.6666666666666ITPR2
TgeneBANK1chr4:86491874chr4:102942670ENST000005086535151_154269.0653.0ITPR2


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ARHGAP24-BANK1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ARHGAP24-BANK1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneARHGAP24C0017668Focal glomerulosclerosis1GENOMICS_ENGLAND
HgeneARHGAP24C1868672NEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE1ORPHANET
HgeneARHGAP24C4049702Focal Segmental Glomerulosclerosis, Not Otherwise Specified1GENOMICS_ENGLAND
TgeneC0024141Lupus Erythematosus, Systemic6CTD_human;ORPHANET
TgeneC0242380Libman-Sacks Disease1CTD_human