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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:OBSCN-IGSF21 (FusionGDB2 ID:HG84033TG84966)

Fusion Gene Summary for OBSCN-IGSF21

check button Fusion gene summary
Fusion gene informationFusion gene name: OBSCN-IGSF21
Fusion gene ID: hg84033tg84966
HgeneTgene
Gene symbol

OBSCN

IGSF21

Gene ID

84033

84966

Gene nameobscurin, cytoskeletal calmodulin and titin-interacting RhoGEFimmunoglobin superfamily member 21
SynonymsARHGEF30|UNC89-
Cytomap('OBSCN')('IGSF21')

1q42.13

1p36.13

Type of geneprotein-codingprotein-coding
Descriptionobscurinobscurin, myosin light chain kinaseobscurin-MLCKimmunoglobulin superfamily member 21
Modification date2020031320200313
UniProtAcc.

Q96ID5

Ensembl transtripts involved in fusion geneENST00000284548, ENST00000422127, 
ENST00000570156, ENST00000366707, 
ENST00000366709, ENST00000359599, 
ENST00000602685, 
Fusion gene scores* DoF score6 X 8 X 3=1444 X 2 X 4=32
# samples 64
** MAII scorelog2(6/144*10)=-1.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/32*10)=0.321928094887362
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: OBSCN [Title/Abstract] AND IGSF21 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointOBSCN(228402799)-IGSF21(18554392), # samples:3
Anticipated loss of major functional domain due to fusion event.OBSCN-IGSF21 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
OBSCN-IGSF21 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
OBSCN-IGSF21 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
OBSCN-IGSF21 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across OBSCN (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across IGSF21 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A1-A0SK-01AOBSCNchr1

228402799

-IGSF21chr1

18554392

+
ChimerDB4BRCATCGA-A1-A0SK-01AOBSCNchr1

228402799

+IGSF21chr1

18554392

+


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Fusion Gene ORF analysis for OBSCN-IGSF21

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000284548ENST00000473951OBSCNchr1

228402799

+IGSF21chr1

18554392

+
5CDS-intronENST00000422127ENST00000473951OBSCNchr1

228402799

+IGSF21chr1

18554392

+
5CDS-intronENST00000570156ENST00000473951OBSCNchr1

228402799

+IGSF21chr1

18554392

+
5UTR-3CDSENST00000366707ENST00000251296OBSCNchr1

228402799

+IGSF21chr1

18554392

+
5UTR-3CDSENST00000366709ENST00000251296OBSCNchr1

228402799

+IGSF21chr1

18554392

+
5UTR-intronENST00000366707ENST00000473951OBSCNchr1

228402799

+IGSF21chr1

18554392

+
5UTR-intronENST00000366709ENST00000473951OBSCNchr1

228402799

+IGSF21chr1

18554392

+
In-frameENST00000284548ENST00000251296OBSCNchr1

228402799

+IGSF21chr1

18554392

+
In-frameENST00000422127ENST00000251296OBSCNchr1

228402799

+IGSF21chr1

18554392

+
In-frameENST00000570156ENST00000251296OBSCNchr1

228402799

+IGSF21chr1

18554392

+
intron-3CDSENST00000359599ENST00000251296OBSCNchr1

228402799

+IGSF21chr1

18554392

+
intron-3CDSENST00000602685ENST00000251296OBSCNchr1

228402799

+IGSF21chr1

18554392

+
intron-intronENST00000359599ENST00000473951OBSCNchr1

228402799

+IGSF21chr1

18554392

+
intron-intronENST00000602685ENST00000473951OBSCNchr1

228402799

+IGSF21chr1

18554392

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000284548OBSCNchr1228402799+ENST00000251296IGSF21chr118554392+339219027432351053
ENST00000570156OBSCNchr1228402799+ENST00000251296IGSF21chr118554392+339219027432351053
ENST00000422127OBSCNchr1228402799+ENST00000251296IGSF21chr118554392+336218724432051053

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000284548ENST00000251296OBSCNchr1228402799+IGSF21chr118554392+0.0006683910.9993316
ENST00000570156ENST00000251296OBSCNchr1228402799+IGSF21chr118554392+0.0006683910.9993316
ENST00000422127ENST00000251296OBSCNchr1228402799+IGSF21chr118554392+0.0006300350.99937004

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Fusion Genomic Features for OBSCN-IGSF21


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
OBSCNchr1228402799+IGSF21chr118554391+0.0007501950.99924976
OBSCNchr1228402799+IGSF21chr118554391+0.0007501950.99924976

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for OBSCN-IGSF21


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:228402799/chr1:18554392)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.IGSF21

Q96ID5

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Involved in synaptic inhibition in the brain. Selectively regulates inhibitory presynaptic differentiation through interacting with presynaptic NRXN2. {ECO:0000250|UniProtKB:Q7TNR6}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+581192_1986096621.0Compositional biasNote=Poly-Ala
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+5105192_1986097969.0Compositional biasNote=Poly-Ala
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+58110_1006096621.0DomainNote=Ig-like 1
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+581110_2026096621.0DomainNote=Ig-like 2
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+581236_3226096621.0DomainNote=Ig-like 3
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+581331_4146096621.0DomainNote=Ig-like 4
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+581420_5086096621.0DomainNote=Ig-like 5
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+581515_6126096621.0DomainFibronectin type-III 1
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+510510_1006097969.0DomainNote=Ig-like 1
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+5105110_2026097969.0DomainNote=Ig-like 2
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+5105236_3226097969.0DomainNote=Ig-like 3
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+5105331_4146097969.0DomainNote=Ig-like 4
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+5105420_5086097969.0DomainNote=Ig-like 5
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+5105515_6126097969.0DomainFibronectin type-III 1
TgeneIGSF21chr1:228402799chr1:18554392ENST0000025129601025_13223468.0DomainNote=Ig-like 1
TgeneIGSF21chr1:228402799chr1:18554392ENST00000251296010344_42923468.0DomainNote=Ig-like 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5811115_11186096621.0Compositional biasNote=Poly-Ser
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5811207_12106096621.0Compositional biasNote=Poly-Ser
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5811299_13026096621.0Compositional biasNote=Poly-Ser
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5811391_13946096621.0Compositional biasNote=Poly-Ser
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5811575_15786096621.0Compositional biasNote=Poly-Ser
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5811667_16706096621.0Compositional biasNote=Poly-Ser
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5814398_44016096621.0Compositional biasNote=Poly-Leu
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5814846_48496096621.0Compositional biasNote=Poly-Gln
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5816789_67966096621.0Compositional biasNote=Poly-Ser
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5816969_71176096621.0Compositional biasNote=Pro-rich
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+581710_7136096621.0Compositional biasNote=Poly-Ala
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+581931_9346096621.0Compositional biasNote=Poly-Ser
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51051115_11186097969.0Compositional biasNote=Poly-Ser
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51051207_12106097969.0Compositional biasNote=Poly-Ser
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51051299_13026097969.0Compositional biasNote=Poly-Ser
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51051391_13946097969.0Compositional biasNote=Poly-Ser
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51051575_15786097969.0Compositional biasNote=Poly-Ser
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51051667_16706097969.0Compositional biasNote=Poly-Ser
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51054398_44016097969.0Compositional biasNote=Poly-Leu
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51054846_48496097969.0Compositional biasNote=Poly-Gln
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51056789_67966097969.0Compositional biasNote=Poly-Ser
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51056969_71176097969.0Compositional biasNote=Pro-rich
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+5105710_7136097969.0Compositional biasNote=Poly-Ala
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+5105931_9346097969.0Compositional biasNote=Poly-Ser
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5811070_11616096621.0DomainNote=Ig-like 11
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5811162_12526096621.0DomainNote=Ig-like 12
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5811254_13456096621.0DomainNote=Ig-like 13
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5811346_14326096621.0DomainNote=Ig-like 14
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5811438_15246096621.0DomainNote=Ig-like 15
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5811530_16216096621.0DomainNote=Ig-like 16
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5811622_17196096621.0DomainNote=Ig-like 17
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5811731_18086096621.0DomainFibronectin type-III 2
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5811809_18946096621.0DomainNote=Ig-like 18
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5811896_19826096621.0DomainNote=Ig-like 19
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5811987_20716096621.0DomainNote=Ig-like 20
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5812077_21626096621.0DomainNote=Ig-like 21
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5812165_22496096621.0DomainNote=Ig-like 22
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5812289_23806096621.0DomainNote=Ig-like 23
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5812468_25596096621.0DomainNote=Ig-like 24
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5812564_26436096621.0DomainNote=Ig-like 25
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5812646_27306096621.0DomainNote=Ig-like 26
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5812736_28236096621.0DomainNote=Ig-like 27
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5812826_29086096621.0DomainNote=Ig-like 28
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5812920_29996096621.0DomainNote=Ig-like 29
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5813003_30926096621.0DomainNote=Ig-like 30
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5813095_31836096621.0DomainNote=Ig-like 31
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5813184_32686096621.0DomainNote=Ig-like 32
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5813273_33566096621.0DomainNote=Ig-like 33
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5813359_34446096621.0DomainNote=Ig-like 34
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5813449_35326096621.0DomainNote=Ig-like 35
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5813537_36206096621.0DomainNote=Ig-like 36
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5813625_37086096621.0DomainNote=Ig-like 37
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5813713_37966096621.0DomainNote=Ig-like 38
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5813801_38846096621.0DomainNote=Ig-like 39
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5813890_39736096621.0DomainNote=Ig-like 40
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5813978_40626096621.0DomainNote=Ig-like 41
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5814068_41606096621.0DomainNote=Ig-like 42
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5814171_42396096621.0DomainNote=Ig-like 43
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5814248_43376096621.0DomainNote=Ig-like 44
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5814340_44276096621.0DomainNote=Ig-like 45
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5814430_45186096621.0DomainNote=Ig-like 46
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5814525_46196096621.0DomainFibronectin type-III 3
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5814624_47146096621.0DomainNote=Ig-like 47
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5814872_49016096621.0DomainIQ
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5814898_49896096621.0DomainNote=Ig-like 48
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5815126_52156096621.0DomainNote=Ig-like 49
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5815260_53496096621.0DomainNote=Ig-like 50
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5815371_54676096621.0DomainNote=Ig-like 51
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5815600_56676096621.0DomainSH3
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5815693_58776096621.0DomainDH
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5815895_60046096621.0DomainPH
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5816014_60976096621.0DomainNote=Ig-like 52
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5816108_62006096621.0DomainNote=Ig-like 53
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+581619_6986096621.0DomainNote=Ig-like 6
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5816357_64456096621.0DomainNote=Ig-like 54
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5816468_67216096621.0DomainProtein kinase 1
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+581701_7906096621.0DomainNote=Ig-like 7
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5817463_75526096621.0DomainNote=Ig-like 55
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5817557_76496096621.0DomainFibronectin type-III 4
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5817672_79246096621.0DomainProtein kinase 2
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+581798_8846096621.0DomainNote=Ig-like 8
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+581886_9776096621.0DomainNote=Ig-like 9
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+581978_10666096621.0DomainNote=Ig-like 10
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51051070_11616097969.0DomainNote=Ig-like 11
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51051162_12526097969.0DomainNote=Ig-like 12
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51051254_13456097969.0DomainNote=Ig-like 13
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51051346_14326097969.0DomainNote=Ig-like 14
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51051438_15246097969.0DomainNote=Ig-like 15
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51051530_16216097969.0DomainNote=Ig-like 16
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51051622_17196097969.0DomainNote=Ig-like 17
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51051731_18086097969.0DomainFibronectin type-III 2
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51051809_18946097969.0DomainNote=Ig-like 18
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51051896_19826097969.0DomainNote=Ig-like 19
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51051987_20716097969.0DomainNote=Ig-like 20
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51052077_21626097969.0DomainNote=Ig-like 21
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51052165_22496097969.0DomainNote=Ig-like 22
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51052289_23806097969.0DomainNote=Ig-like 23
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51052468_25596097969.0DomainNote=Ig-like 24
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51052564_26436097969.0DomainNote=Ig-like 25
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51052646_27306097969.0DomainNote=Ig-like 26
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51052736_28236097969.0DomainNote=Ig-like 27
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51052826_29086097969.0DomainNote=Ig-like 28
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51052920_29996097969.0DomainNote=Ig-like 29
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51053003_30926097969.0DomainNote=Ig-like 30
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51053095_31836097969.0DomainNote=Ig-like 31
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51053184_32686097969.0DomainNote=Ig-like 32
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51053273_33566097969.0DomainNote=Ig-like 33
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51053359_34446097969.0DomainNote=Ig-like 34
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51053449_35326097969.0DomainNote=Ig-like 35
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51053537_36206097969.0DomainNote=Ig-like 36
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51053625_37086097969.0DomainNote=Ig-like 37
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51053713_37966097969.0DomainNote=Ig-like 38
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51053801_38846097969.0DomainNote=Ig-like 39
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51053890_39736097969.0DomainNote=Ig-like 40
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51053978_40626097969.0DomainNote=Ig-like 41
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51054068_41606097969.0DomainNote=Ig-like 42
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51054171_42396097969.0DomainNote=Ig-like 43
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51054248_43376097969.0DomainNote=Ig-like 44
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51054340_44276097969.0DomainNote=Ig-like 45
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51054430_45186097969.0DomainNote=Ig-like 46
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51054525_46196097969.0DomainFibronectin type-III 3
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51054624_47146097969.0DomainNote=Ig-like 47
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51054872_49016097969.0DomainIQ
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51054898_49896097969.0DomainNote=Ig-like 48
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51055126_52156097969.0DomainNote=Ig-like 49
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51055260_53496097969.0DomainNote=Ig-like 50
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51055371_54676097969.0DomainNote=Ig-like 51
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51055600_56676097969.0DomainSH3
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51055693_58776097969.0DomainDH
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51055895_60046097969.0DomainPH
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51056014_60976097969.0DomainNote=Ig-like 52
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51056108_62006097969.0DomainNote=Ig-like 53
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+5105619_6986097969.0DomainNote=Ig-like 6
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51056357_64456097969.0DomainNote=Ig-like 54
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51056468_67216097969.0DomainProtein kinase 1
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+5105701_7906097969.0DomainNote=Ig-like 7
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51057463_75526097969.0DomainNote=Ig-like 55
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51057557_76496097969.0DomainFibronectin type-III 4
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51057672_79246097969.0DomainProtein kinase 2
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+5105798_8846097969.0DomainNote=Ig-like 8
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+5105886_9776097969.0DomainNote=Ig-like 9
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+5105978_10666097969.0DomainNote=Ig-like 10
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5816474_64826096621.0Nucleotide bindingATP
HgeneOBSCNchr1:228402799chr1:18554392ENST00000284548+5817678_76866096621.0Nucleotide bindingATP
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51056474_64826097969.0Nucleotide bindingATP
HgeneOBSCNchr1:228402799chr1:18554392ENST00000422127+51057678_76866097969.0Nucleotide bindingATP


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Fusion Gene Sequence for OBSCN-IGSF21


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>61306_61306_1_OBSCN-IGSF21_OBSCN_chr1_228402799_ENST00000284548_IGSF21_chr1_18554392_ENST00000251296_length(transcript)=3392nt_BP=1902nt
TGCCTCCCAGCCTGTGCCCCCAGCCTGCGTGCTGCCCAGAGCCCCCATAGAGAGAGGTCCCCGCCGCCACCCTCATGGATCAGCCACAGT
TCAGCGGGGCGCCCCGCTTTCTCACCCGGCCCAAGGCCTTCGTGGTGTCGGTGGGCAAGGACGCCACCCTCAGCTGCCAGATCGTGGGTA
ATCCCACGCCACAGGTGAGCTGGGAGAAGGACCAGCAGCCGGTGGCGGCCGGCGCGCGCTTCCGTCTGGCCCAGGACGGCGACCTCTACC
GCCTCACTATCCTGGACCTGGCGCTGGGCGACAGTGGGCAATACGTGTGCCGCGCGCGCAATGCCATAGGCGAGGCCTTCGCTGCTGTGG
GCCTGCAGGTGGACGCGGAGGCCGCGTGCGCCGAGCAGGCGCCGCACTTCCTGCTGCGGCCCACGTCCATCCGCGTGCGCGAGGGCTCAG
AGGCCACCTTCCGCTGCCGCGTGGGTGGCTCCCCGAGGCCGGCAGTGAGCTGGTCCAAGGACGGGCGGCGCCTGGGTGAGCCCGACGGCC
CCCGCGTGCGCGTGGAGGAGCTCGGCGAGGCAAGTGCGCTGCGCATTCGGGCGGCGCGGCCGCGCGACGGCGGCACTTACGAGGTCCGCG
CCGAGAACCCGCTGGGCGCTGCCAGCGCCGCCGCGGCGCTAGTGGTGGACTCGGACGCCGCGGACACGGCCAGCCGGCCCGGGACCTCCA
CGGCCGCGCTCCTGGCGCACCTGCAGCGGCGGCGCGAGGCTATGCGCGCCGAGGGCGCCCCCGCCTCACCGCCCAGCACCGGCACGCGCA
CCTGCACGGTGACTGAAGGCAAGCACGCGCGCCTCAGCTGCTACGTGACCGGCGAGCCCAAGCCCGAGACGGTGTGGAAGAAGGACGGCC
AGCTGGTGACCGAGGGCCGGCGCCACGTGGTGTACGAGGACGCGCAGGAGAACTTCGTGCTCAAGATCCTCTTCTGCAAGCAGTCGGACC
GCGGCCTCTACACCTGCACGGCGTCCAACCTCGTGGGCCAGACCTACAGCTCTGTGCTGGTCGTAGTGCGCGAGCCCGCGGTTCCCTTCA
AAAAGCGGCTGCAAGATCTGGAGGTGCGGGAGAAGGAGTCGGCCACGTTCCTATGTGAGGTGCCCCAGCCGTCCACTGAGGCCGCGTGGT
TCAAGGAGGAGACGCGGTTGTGGGCGAGCGCCAAGTACGGCATCGAGGAGGAGGGCACCGAGCGCCGCCTGACCGTGCGCAATGTCTCGG
CCGACGACGACGCGGTGTACATCTGCGAGACGCCAGAGGGCAGCCGCACGGTGGCGGAGCTCGCAGTCCAAGGAAACCTCCTCCGAAAGC
TCCCTCGGAAGACGGCGGTGCGCGTGGGCGACACGGCTATGTTTTGCGTGGAGCTGGCGGTCCCGGTGGGCCCCGTCCACTGGCTGCGGA
ACCAGGAGGAAGTGGTGGCGGGGGGCCGCGTGGCCATCTCCGCGGAGGGCACGCGCCACACACTAACCATCTCCCAGTGCTGCCTGGAGG
ATGTGGGCCAGGTGGCCTTTATGGCTGGCGACTGCCAGACGTCCACCCAGTTCTGCGTGTCGGCCCCCAGGAAGCCTCCCCTGCAACCCC
CTGTGGATCCTGTGGTAAAGGCCAGGATGGAGAGTTCCGTGATTCTCAGCTGGTCCCCACCACCCCATGGGGAACGCCCTGTCACTATCG
ACGGCTACCTGGTAGAGAAGAAGAAGCTTGGCACCTACACCTGGATCAGGTGCCACGAGGCTGAATGGGTGGCTACACCTGAGCTGACCG
TGGCTGATGTGGCGGAGGAGGGGAACTTCCAGTTCCGAGTGTCCGCTCTCAACAGCTTTGGTCAGAGTCCCTACCTCGAGTTCCCGGGGA
CTGTCCACCTGGGCTACCTGACAGTCAACATTGAGCCTCTCCCCCCTGTGGTGGCTGGAGACGCCGTGACTTTGAAGTGTAACTTCAAGA
CAGATGGGCGCATGCGGGAGATCGTGTGGTACCGGGTGACGGATGGTGGCACCATCAAGCAAAAGATCTTCACCTTCGACGCCATGTTCT
CCACCAACTACTCACACATGGAGAACTACCGCAAGCGAGAGGACCTGGTGTACCAGTCCACTGTGAGGCTGCCCGAGGTCCGGATCTCAG
ACAATGGTCCCTATGAGTGCCATGTGGGCATCTACGACCGCGCCACCAGGGAGAAGGTGGTCCTGGCATCAGGCAACATCTTCCTCAACG
TCATGGCTCCTCCCACCTCCATTGAAGTGGTGGCTGCTGACACACCAGCCCCCTTCAGCCGCTACCAAGCCCAGAACTTCACGCTGGTCT
GCATCGTGTCTGGAGGAAAACCAGCACCCATGGTTTATTTCAAACGAGATGGGGAACCAATCGACGCAGTGCCCCTATCAGAGCCACCAG
CTGCGAGCTCCGGCCCCCTACAGGACAGCAGGCCCTTCCGCAGCCTTCTGCACCGTGACCTGGATGACACCAAGATGCAGAAGTCACTGT
CCCTCCTGGACGCCGAGAACCGGGGTGGGCGACCCTACACGGAGCGCCCCTCCCGTGGCCTGACCCCAGATCCCAACATCCTCCTCCAGC
CAACCACAGAGAACATACCAGAGACGGTCGTGAGCCGTGAGTTTCCCCGCTGGGTCCACAGCGCCGAGCCCACCTACTTCCTGCGCCACA
GCCGCACCCCGAGCAGTGACGGCACTGTGGAAGTACGTGCCCTGCTCACCTGGACCCTCAACCCACAGATCGACAACGAGGCCCTCTTCA
GCTGCGAGGTCAAGCACCCAGCTCTGTCGATGCCCATGCAGGCAGAGGTCACGCTGGTTGCCCCCAAAGGACCCAAAATTGTGATGACGC
CCAGCAGAGCCCGGGTAGGGGACACAGTGAGGATTCTGGTCCATGGGTTTCAGAACGAAGTCTTCCCGGAGCCCATGTTCACGTGGACGC
GGGTTGGGAGCCGCCTCCTGGACGGCAGCGCTGAGTTCGACGGGAAGGAGCTGGTGCTGGAGCGGGTTCCCGCCGAGCTCAATGGCTCCA
TGTATCGCTGCACCGCCCAGAACCCACTGGGCTCCACCGACACGCACACCCGGCTCATCGTGTTTGAAAACCCAAATATCCCAAGAGGAA
CGGAGGACTCTAATGGTTCCATTGGCCCCACTGGTGCCCGGCTCACCTTGGTGCTCGCCCTGACAGTGATTCTGGAGCTGACGTGAAGGC
ACCCGCCCCGGCCACTCCATCAGGCACTGACATCTCCACGACCGGTTTTCATTTCTTTTCTAAACTATTTCCAGTCTTGTTCTTAGTCTC
TTTCCATCTGTGTCTTGGCTTCTTCAGTCGGTTTAATTAAAACAAACAGAACAATTTTCCCC

>61306_61306_1_OBSCN-IGSF21_OBSCN_chr1_228402799_ENST00000284548_IGSF21_chr1_18554392_ENST00000251296_length(amino acids)=1053AA_BP=609
MDQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIGE
AFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGG
TYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETV
WKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEVPQPS
TEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEGSRTVAELAVQGNLLRKLPRKTAVRVGDTAMFCVELAVPVGP
VHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCLEDVGQVAFMAGDCQTSTQFCVSAPRKPPLQPPVDPVVKARMESSVILSWSPPPHGE
RPVTIDGYLVEKKKLGTYTWIRCHEAEWVATPELTVADVAEEGNFQFRVSALNSFGQSPYLEFPGTVHLGYLTVNIEPLPPVVAGDAVTL
KCNFKTDGRMREIVWYRVTDGGTIKQKIFTFDAMFSTNYSHMENYRKREDLVYQSTVRLPEVRISDNGPYECHVGIYDRATREKVVLASG
NIFLNVMAPPTSIEVVAADTPAPFSRYQAQNFTLVCIVSGGKPAPMVYFKRDGEPIDAVPLSEPPAASSGPLQDSRPFRSLLHRDLDDTK
MQKSLSLLDAENRGGRPYTERPSRGLTPDPNILLQPTTENIPETVVSREFPRWVHSAEPTYFLRHSRTPSSDGTVEVRALLTWTLNPQID
NEALFSCEVKHPALSMPMQAEVTLVAPKGPKIVMTPSRARVGDTVRILVHGFQNEVFPEPMFTWTRVGSRLLDGSAEFDGKELVLERVPA
ELNGSMYRCTAQNPLGSTDTHTRLIVFENPNIPRGTEDSNGSIGPTGARLTLVLALTVILELT

--------------------------------------------------------------
>61306_61306_2_OBSCN-IGSF21_OBSCN_chr1_228402799_ENST00000422127_IGSF21_chr1_18554392_ENST00000251296_length(transcript)=3362nt_BP=1872nt
GCTGCCCAGAGCCCCCATAGAGAGAGGTCCCCGCCGCCACCCTCATGGATCAGCCACAGTTCAGCGGGGCGCCCCGCTTTCTCACCCGGC
CCAAGGCCTTCGTGGTGTCGGTGGGCAAGGACGCCACCCTCAGCTGCCAGATCGTGGGTAATCCCACGCCACAGGTGAGCTGGGAGAAGG
ACCAGCAGCCGGTGGCGGCCGGCGCGCGCTTCCGTCTGGCCCAGGACGGCGACCTCTACCGCCTCACTATCCTGGACCTGGCGCTGGGCG
ACAGTGGGCAATACGTGTGCCGCGCGCGCAATGCCATAGGCGAGGCCTTCGCTGCTGTGGGCCTGCAGGTGGACGCGGAGGCCGCGTGCG
CCGAGCAGGCGCCGCACTTCCTGCTGCGGCCCACGTCCATCCGCGTGCGCGAGGGCTCAGAGGCCACCTTCCGCTGCCGCGTGGGTGGCT
CCCCGAGGCCGGCAGTGAGCTGGTCCAAGGACGGGCGGCGCCTGGGTGAGCCCGACGGCCCCCGCGTGCGCGTGGAGGAGCTCGGCGAGG
CAAGTGCGCTGCGCATTCGGGCGGCGCGGCCGCGCGACGGCGGCACTTACGAGGTCCGCGCCGAGAACCCGCTGGGCGCTGCCAGCGCCG
CCGCGGCGCTAGTGGTGGACTCGGACGCCGCGGACACGGCCAGCCGGCCCGGGACCTCCACGGCCGCGCTCCTGGCGCACCTGCAGCGGC
GGCGCGAGGCTATGCGCGCCGAGGGCGCCCCCGCCTCACCGCCCAGCACCGGCACGCGCACCTGCACGGTGACTGAAGGCAAGCACGCGC
GCCTCAGCTGCTACGTGACCGGCGAGCCCAAGCCCGAGACGGTGTGGAAGAAGGACGGCCAGCTGGTGACCGAGGGCCGGCGCCACGTGG
TGTACGAGGACGCGCAGGAGAACTTCGTGCTCAAGATCCTCTTCTGCAAGCAGTCGGACCGCGGCCTCTACACCTGCACGGCGTCCAACC
TCGTGGGCCAGACCTACAGCTCTGTGCTGGTCGTAGTGCGCGAGCCCGCGGTTCCCTTCAAAAAGCGGCTGCAAGATCTGGAGGTGCGGG
AGAAGGAGTCGGCCACGTTCCTATGTGAGGTGCCCCAGCCGTCCACTGAGGCCGCGTGGTTCAAGGAGGAGACGCGGTTGTGGGCGAGCG
CCAAGTACGGCATCGAGGAGGAGGGCACCGAGCGCCGCCTGACCGTGCGCAATGTCTCGGCCGACGACGACGCGGTGTACATCTGCGAGA
CGCCAGAGGGCAGCCGCACGGTGGCGGAGCTCGCAGTCCAAGGAAACCTCCTCCGAAAGCTCCCTCGGAAGACGGCGGTGCGCGTGGGCG
ACACGGCTATGTTTTGCGTGGAGCTGGCGGTCCCGGTGGGCCCCGTCCACTGGCTGCGGAACCAGGAGGAAGTGGTGGCGGGGGGCCGCG
TGGCCATCTCCGCGGAGGGCACGCGCCACACACTAACCATCTCCCAGTGCTGCCTGGAGGATGTGGGCCAGGTGGCCTTTATGGCTGGCG
ACTGCCAGACGTCCACCCAGTTCTGCGTGTCGGCCCCCAGGAAGCCTCCCCTGCAACCCCCTGTGGATCCTGTGGTAAAGGCCAGGATGG
AGAGTTCCGTGATTCTCAGCTGGTCCCCACCACCCCATGGGGAACGCCCTGTCACTATCGACGGCTACCTGGTAGAGAAGAAGAAGCTTG
GCACCTACACCTGGATCAGGTGCCACGAGGCTGAATGGGTGGCTACACCTGAGCTGACCGTGGCTGATGTGGCGGAGGAGGGGAACTTCC
AGTTCCGAGTGTCCGCTCTCAACAGCTTTGGTCAGAGTCCCTACCTCGAGTTCCCGGGGACTGTCCACCTGGGCTACCTGACAGTCAACA
TTGAGCCTCTCCCCCCTGTGGTGGCTGGAGACGCCGTGACTTTGAAGTGTAACTTCAAGACAGATGGGCGCATGCGGGAGATCGTGTGGT
ACCGGGTGACGGATGGTGGCACCATCAAGCAAAAGATCTTCACCTTCGACGCCATGTTCTCCACCAACTACTCACACATGGAGAACTACC
GCAAGCGAGAGGACCTGGTGTACCAGTCCACTGTGAGGCTGCCCGAGGTCCGGATCTCAGACAATGGTCCCTATGAGTGCCATGTGGGCA
TCTACGACCGCGCCACCAGGGAGAAGGTGGTCCTGGCATCAGGCAACATCTTCCTCAACGTCATGGCTCCTCCCACCTCCATTGAAGTGG
TGGCTGCTGACACACCAGCCCCCTTCAGCCGCTACCAAGCCCAGAACTTCACGCTGGTCTGCATCGTGTCTGGAGGAAAACCAGCACCCA
TGGTTTATTTCAAACGAGATGGGGAACCAATCGACGCAGTGCCCCTATCAGAGCCACCAGCTGCGAGCTCCGGCCCCCTACAGGACAGCA
GGCCCTTCCGCAGCCTTCTGCACCGTGACCTGGATGACACCAAGATGCAGAAGTCACTGTCCCTCCTGGACGCCGAGAACCGGGGTGGGC
GACCCTACACGGAGCGCCCCTCCCGTGGCCTGACCCCAGATCCCAACATCCTCCTCCAGCCAACCACAGAGAACATACCAGAGACGGTCG
TGAGCCGTGAGTTTCCCCGCTGGGTCCACAGCGCCGAGCCCACCTACTTCCTGCGCCACAGCCGCACCCCGAGCAGTGACGGCACTGTGG
AAGTACGTGCCCTGCTCACCTGGACCCTCAACCCACAGATCGACAACGAGGCCCTCTTCAGCTGCGAGGTCAAGCACCCAGCTCTGTCGA
TGCCCATGCAGGCAGAGGTCACGCTGGTTGCCCCCAAAGGACCCAAAATTGTGATGACGCCCAGCAGAGCCCGGGTAGGGGACACAGTGA
GGATTCTGGTCCATGGGTTTCAGAACGAAGTCTTCCCGGAGCCCATGTTCACGTGGACGCGGGTTGGGAGCCGCCTCCTGGACGGCAGCG
CTGAGTTCGACGGGAAGGAGCTGGTGCTGGAGCGGGTTCCCGCCGAGCTCAATGGCTCCATGTATCGCTGCACCGCCCAGAACCCACTGG
GCTCCACCGACACGCACACCCGGCTCATCGTGTTTGAAAACCCAAATATCCCAAGAGGAACGGAGGACTCTAATGGTTCCATTGGCCCCA
CTGGTGCCCGGCTCACCTTGGTGCTCGCCCTGACAGTGATTCTGGAGCTGACGTGAAGGCACCCGCCCCGGCCACTCCATCAGGCACTGA
CATCTCCACGACCGGTTTTCATTTCTTTTCTAAACTATTTCCAGTCTTGTTCTTAGTCTCTTTCCATCTGTGTCTTGGCTTCTTCAGTCG
GTTTAATTAAAACAAACAGAACAATTTTCCCC

>61306_61306_2_OBSCN-IGSF21_OBSCN_chr1_228402799_ENST00000422127_IGSF21_chr1_18554392_ENST00000251296_length(amino acids)=1053AA_BP=609
MDQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIGE
AFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGG
TYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETV
WKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEVPQPS
TEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEGSRTVAELAVQGNLLRKLPRKTAVRVGDTAMFCVELAVPVGP
VHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCLEDVGQVAFMAGDCQTSTQFCVSAPRKPPLQPPVDPVVKARMESSVILSWSPPPHGE
RPVTIDGYLVEKKKLGTYTWIRCHEAEWVATPELTVADVAEEGNFQFRVSALNSFGQSPYLEFPGTVHLGYLTVNIEPLPPVVAGDAVTL
KCNFKTDGRMREIVWYRVTDGGTIKQKIFTFDAMFSTNYSHMENYRKREDLVYQSTVRLPEVRISDNGPYECHVGIYDRATREKVVLASG
NIFLNVMAPPTSIEVVAADTPAPFSRYQAQNFTLVCIVSGGKPAPMVYFKRDGEPIDAVPLSEPPAASSGPLQDSRPFRSLLHRDLDDTK
MQKSLSLLDAENRGGRPYTERPSRGLTPDPNILLQPTTENIPETVVSREFPRWVHSAEPTYFLRHSRTPSSDGTVEVRALLTWTLNPQID
NEALFSCEVKHPALSMPMQAEVTLVAPKGPKIVMTPSRARVGDTVRILVHGFQNEVFPEPMFTWTRVGSRLLDGSAEFDGKELVLERVPA
ELNGSMYRCTAQNPLGSTDTHTRLIVFENPNIPRGTEDSNGSIGPTGARLTLVLALTVILELT

--------------------------------------------------------------
>61306_61306_3_OBSCN-IGSF21_OBSCN_chr1_228402799_ENST00000570156_IGSF21_chr1_18554392_ENST00000251296_length(transcript)=3392nt_BP=1902nt
TGCCTCCCAGCCTGTGCCCCCAGCCTGCGTGCTGCCCAGAGCCCCCATAGAGAGAGGTCCCCGCCGCCACCCTCATGGATCAGCCACAGT
TCAGCGGGGCGCCCCGCTTTCTCACCCGGCCCAAGGCCTTCGTGGTGTCGGTGGGCAAGGACGCCACCCTCAGCTGCCAGATCGTGGGTA
ATCCCACGCCACAGGTGAGCTGGGAGAAGGACCAGCAGCCGGTGGCGGCCGGCGCGCGCTTCCGTCTGGCCCAGGACGGCGACCTCTACC
GCCTCACTATCCTGGACCTGGCGCTGGGCGACAGTGGGCAATACGTGTGCCGCGCGCGCAATGCCATAGGCGAGGCCTTCGCTGCTGTGG
GCCTGCAGGTGGACGCGGAGGCCGCGTGCGCCGAGCAGGCGCCGCACTTCCTGCTGCGGCCCACGTCCATCCGCGTGCGCGAGGGCTCAG
AGGCCACCTTCCGCTGCCGCGTGGGTGGCTCCCCGAGGCCGGCAGTGAGCTGGTCCAAGGACGGGCGGCGCCTGGGTGAGCCCGACGGCC
CCCGCGTGCGCGTGGAGGAGCTCGGCGAGGCAAGTGCGCTGCGCATTCGGGCGGCGCGGCCGCGCGACGGCGGCACTTACGAGGTCCGCG
CCGAGAACCCGCTGGGCGCTGCCAGCGCCGCCGCGGCGCTAGTGGTGGACTCGGACGCCGCGGACACGGCCAGCCGGCCCGGGACCTCCA
CGGCCGCGCTCCTGGCGCACCTGCAGCGGCGGCGCGAGGCTATGCGCGCCGAGGGCGCCCCCGCCTCACCGCCCAGCACCGGCACGCGCA
CCTGCACGGTGACTGAAGGCAAGCACGCGCGCCTCAGCTGCTACGTGACCGGCGAGCCCAAGCCCGAGACGGTGTGGAAGAAGGACGGCC
AGCTGGTGACCGAGGGCCGGCGCCACGTGGTGTACGAGGACGCGCAGGAGAACTTCGTGCTCAAGATCCTCTTCTGCAAGCAGTCGGACC
GCGGCCTCTACACCTGCACGGCGTCCAACCTCGTGGGCCAGACCTACAGCTCTGTGCTGGTCGTAGTGCGCGAGCCCGCGGTTCCCTTCA
AAAAGCGGCTGCAAGATCTGGAGGTGCGGGAGAAGGAGTCGGCCACGTTCCTATGTGAGGTGCCCCAGCCGTCCACTGAGGCCGCGTGGT
TCAAGGAGGAGACGCGGTTGTGGGCGAGCGCCAAGTACGGCATCGAGGAGGAGGGCACCGAGCGCCGCCTGACCGTGCGCAATGTCTCGG
CCGACGACGACGCGGTGTACATCTGCGAGACGCCAGAGGGCAGCCGCACGGTGGCGGAGCTCGCAGTCCAAGGAAACCTCCTCCGAAAGC
TCCCTCGGAAGACGGCGGTGCGCGTGGGCGACACGGCTATGTTTTGCGTGGAGCTGGCGGTCCCGGTGGGCCCCGTCCACTGGCTGCGGA
ACCAGGAGGAAGTGGTGGCGGGGGGCCGCGTGGCCATCTCCGCGGAGGGCACGCGCCACACACTAACCATCTCCCAGTGCTGCCTGGAGG
ATGTGGGCCAGGTGGCCTTTATGGCTGGCGACTGCCAGACGTCCACCCAGTTCTGCGTGTCGGCCCCCAGGAAGCCTCCCCTGCAACCCC
CTGTGGATCCTGTGGTAAAGGCCAGGATGGAGAGTTCCGTGATTCTCAGCTGGTCCCCACCACCCCATGGGGAACGCCCTGTCACTATCG
ACGGCTACCTGGTAGAGAAGAAGAAGCTTGGCACCTACACCTGGATCAGGTGCCACGAGGCTGAATGGGTGGCTACACCTGAGCTGACCG
TGGCTGATGTGGCGGAGGAGGGGAACTTCCAGTTCCGAGTGTCCGCTCTCAACAGCTTTGGTCAGAGTCCCTACCTCGAGTTCCCGGGGA
CTGTCCACCTGGGCTACCTGACAGTCAACATTGAGCCTCTCCCCCCTGTGGTGGCTGGAGACGCCGTGACTTTGAAGTGTAACTTCAAGA
CAGATGGGCGCATGCGGGAGATCGTGTGGTACCGGGTGACGGATGGTGGCACCATCAAGCAAAAGATCTTCACCTTCGACGCCATGTTCT
CCACCAACTACTCACACATGGAGAACTACCGCAAGCGAGAGGACCTGGTGTACCAGTCCACTGTGAGGCTGCCCGAGGTCCGGATCTCAG
ACAATGGTCCCTATGAGTGCCATGTGGGCATCTACGACCGCGCCACCAGGGAGAAGGTGGTCCTGGCATCAGGCAACATCTTCCTCAACG
TCATGGCTCCTCCCACCTCCATTGAAGTGGTGGCTGCTGACACACCAGCCCCCTTCAGCCGCTACCAAGCCCAGAACTTCACGCTGGTCT
GCATCGTGTCTGGAGGAAAACCAGCACCCATGGTTTATTTCAAACGAGATGGGGAACCAATCGACGCAGTGCCCCTATCAGAGCCACCAG
CTGCGAGCTCCGGCCCCCTACAGGACAGCAGGCCCTTCCGCAGCCTTCTGCACCGTGACCTGGATGACACCAAGATGCAGAAGTCACTGT
CCCTCCTGGACGCCGAGAACCGGGGTGGGCGACCCTACACGGAGCGCCCCTCCCGTGGCCTGACCCCAGATCCCAACATCCTCCTCCAGC
CAACCACAGAGAACATACCAGAGACGGTCGTGAGCCGTGAGTTTCCCCGCTGGGTCCACAGCGCCGAGCCCACCTACTTCCTGCGCCACA
GCCGCACCCCGAGCAGTGACGGCACTGTGGAAGTACGTGCCCTGCTCACCTGGACCCTCAACCCACAGATCGACAACGAGGCCCTCTTCA
GCTGCGAGGTCAAGCACCCAGCTCTGTCGATGCCCATGCAGGCAGAGGTCACGCTGGTTGCCCCCAAAGGACCCAAAATTGTGATGACGC
CCAGCAGAGCCCGGGTAGGGGACACAGTGAGGATTCTGGTCCATGGGTTTCAGAACGAAGTCTTCCCGGAGCCCATGTTCACGTGGACGC
GGGTTGGGAGCCGCCTCCTGGACGGCAGCGCTGAGTTCGACGGGAAGGAGCTGGTGCTGGAGCGGGTTCCCGCCGAGCTCAATGGCTCCA
TGTATCGCTGCACCGCCCAGAACCCACTGGGCTCCACCGACACGCACACCCGGCTCATCGTGTTTGAAAACCCAAATATCCCAAGAGGAA
CGGAGGACTCTAATGGTTCCATTGGCCCCACTGGTGCCCGGCTCACCTTGGTGCTCGCCCTGACAGTGATTCTGGAGCTGACGTGAAGGC
ACCCGCCCCGGCCACTCCATCAGGCACTGACATCTCCACGACCGGTTTTCATTTCTTTTCTAAACTATTTCCAGTCTTGTTCTTAGTCTC
TTTCCATCTGTGTCTTGGCTTCTTCAGTCGGTTTAATTAAAACAAACAGAACAATTTTCCCC

>61306_61306_3_OBSCN-IGSF21_OBSCN_chr1_228402799_ENST00000570156_IGSF21_chr1_18554392_ENST00000251296_length(amino acids)=1053AA_BP=609
MDQPQFSGAPRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQYVCRARNAIGE
AFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGG
TYEVRAENPLGAASAAAALVVDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTCTVTEGKHARLSCYVTGEPKPETV
WKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEVPQPS
TEAAWFKEETRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEGSRTVAELAVQGNLLRKLPRKTAVRVGDTAMFCVELAVPVGP
VHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCLEDVGQVAFMAGDCQTSTQFCVSAPRKPPLQPPVDPVVKARMESSVILSWSPPPHGE
RPVTIDGYLVEKKKLGTYTWIRCHEAEWVATPELTVADVAEEGNFQFRVSALNSFGQSPYLEFPGTVHLGYLTVNIEPLPPVVAGDAVTL
KCNFKTDGRMREIVWYRVTDGGTIKQKIFTFDAMFSTNYSHMENYRKREDLVYQSTVRLPEVRISDNGPYECHVGIYDRATREKVVLASG
NIFLNVMAPPTSIEVVAADTPAPFSRYQAQNFTLVCIVSGGKPAPMVYFKRDGEPIDAVPLSEPPAASSGPLQDSRPFRSLLHRDLDDTK
MQKSLSLLDAENRGGRPYTERPSRGLTPDPNILLQPTTENIPETVVSREFPRWVHSAEPTYFLRHSRTPSSDGTVEVRALLTWTLNPQID
NEALFSCEVKHPALSMPMQAEVTLVAPKGPKIVMTPSRARVGDTVRILVHGFQNEVFPEPMFTWTRVGSRLLDGSAEFDGKELVLERVPA
ELNGSMYRCTAQNPLGSTDTHTRLIVFENPNIPRGTEDSNGSIGPTGARLTLVLALTVILELT

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Fusion Gene PPI Analysis for OBSCN-IGSF21


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for OBSCN-IGSF21


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for OBSCN-IGSF21


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneOBSCNC0007194Hypertrophic Cardiomyopathy4CLINGEN
TgeneC0005684Malignant neoplasm of urinary bladder1CTD_human
TgeneC0005695Bladder Neoplasm1CTD_human