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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ACSS1-DOCK9 (FusionGDB2 ID:HG84532TG23348)

Fusion Gene Summary for ACSS1-DOCK9

check button Fusion gene summary
Fusion gene informationFusion gene name: ACSS1-DOCK9
Fusion gene ID: hg84532tg23348
HgeneTgene
Gene symbol

ACSS1

DOCK9

Gene ID

84532

23348

Gene nameacyl-CoA synthetase short chain family member 1dedicator of cytokinesis 9
SynonymsACAS2L|ACECS1|AceCS2LZIZ1|ZIZIMIN1
Cytomap('ACSS1')('DOCK9')

20p11.21

13q32.3

Type of geneprotein-codingprotein-coding
Descriptionacetyl-coenzyme A synthetase 2-like, mitochondrialacetate--CoA ligase 2propionate--CoA ligasededicator of cytokinesis protein 9cdc42 guanine nucleotide exchange factor zizimin-1
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000323482, ENST00000432802, 
ENST00000537502, ENST00000542618, 
ENST00000376726, ENST00000484396, 
Fusion gene scores* DoF score9 X 8 X 7=50414 X 18 X 6=1512
# samples 919
** MAII scorelog2(9/504*10)=-2.48542682717024
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(19/1512*10)=-2.99238681589013
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ACSS1 [Title/Abstract] AND DOCK9 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointACSS1(25011394)-DOCK9(99508285), # samples:1
Anticipated loss of major functional domain due to fusion event.ACSS1-DOCK9 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ACSS1-DOCK9 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ACSS1-DOCK9 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ACSS1-DOCK9 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ACSS1-DOCK9 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
ACSS1-DOCK9 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneACSS1

GO:0006085

acetyl-CoA biosynthetic process

16788062


check buttonFusion gene breakpoints across ACSS1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across DOCK9 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4THCATCGA-KS-A4I7ACSS1chr20

25011394

-DOCK9chr13

99508285

-


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Fusion Gene ORF analysis for ACSS1-DOCK9

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000323482ENST00000442173ACSS1chr20

25011394

-DOCK9chr13

99508285

-
5CDS-intronENST00000323482ENST00000461998ACSS1chr20

25011394

-DOCK9chr13

99508285

-
5CDS-intronENST00000432802ENST00000442173ACSS1chr20

25011394

-DOCK9chr13

99508285

-
5CDS-intronENST00000432802ENST00000461998ACSS1chr20

25011394

-DOCK9chr13

99508285

-
5CDS-intronENST00000537502ENST00000442173ACSS1chr20

25011394

-DOCK9chr13

99508285

-
5CDS-intronENST00000537502ENST00000461998ACSS1chr20

25011394

-DOCK9chr13

99508285

-
5CDS-intronENST00000542618ENST00000442173ACSS1chr20

25011394

-DOCK9chr13

99508285

-
5CDS-intronENST00000542618ENST00000461998ACSS1chr20

25011394

-DOCK9chr13

99508285

-
Frame-shiftENST00000537502ENST00000339416ACSS1chr20

25011394

-DOCK9chr13

99508285

-
Frame-shiftENST00000537502ENST00000376460ACSS1chr20

25011394

-DOCK9chr13

99508285

-
Frame-shiftENST00000537502ENST00000448493ACSS1chr20

25011394

-DOCK9chr13

99508285

-
In-frameENST00000323482ENST00000339416ACSS1chr20

25011394

-DOCK9chr13

99508285

-
In-frameENST00000323482ENST00000376460ACSS1chr20

25011394

-DOCK9chr13

99508285

-
In-frameENST00000323482ENST00000448493ACSS1chr20

25011394

-DOCK9chr13

99508285

-
In-frameENST00000432802ENST00000339416ACSS1chr20

25011394

-DOCK9chr13

99508285

-
In-frameENST00000432802ENST00000376460ACSS1chr20

25011394

-DOCK9chr13

99508285

-
In-frameENST00000432802ENST00000448493ACSS1chr20

25011394

-DOCK9chr13

99508285

-
In-frameENST00000542618ENST00000339416ACSS1chr20

25011394

-DOCK9chr13

99508285

-
In-frameENST00000542618ENST00000376460ACSS1chr20

25011394

-DOCK9chr13

99508285

-
In-frameENST00000542618ENST00000448493ACSS1chr20

25011394

-DOCK9chr13

99508285

-
intron-3CDSENST00000376726ENST00000339416ACSS1chr20

25011394

-DOCK9chr13

99508285

-
intron-3CDSENST00000376726ENST00000376460ACSS1chr20

25011394

-DOCK9chr13

99508285

-
intron-3CDSENST00000376726ENST00000448493ACSS1chr20

25011394

-DOCK9chr13

99508285

-
intron-3CDSENST00000484396ENST00000339416ACSS1chr20

25011394

-DOCK9chr13

99508285

-
intron-3CDSENST00000484396ENST00000376460ACSS1chr20

25011394

-DOCK9chr13

99508285

-
intron-3CDSENST00000484396ENST00000448493ACSS1chr20

25011394

-DOCK9chr13

99508285

-
intron-intronENST00000376726ENST00000442173ACSS1chr20

25011394

-DOCK9chr13

99508285

-
intron-intronENST00000376726ENST00000461998ACSS1chr20

25011394

-DOCK9chr13

99508285

-
intron-intronENST00000484396ENST00000442173ACSS1chr20

25011394

-DOCK9chr13

99508285

-
intron-intronENST00000484396ENST00000461998ACSS1chr20

25011394

-DOCK9chr13

99508285

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000323482ACSS1chr2025011394-ENST00000376460DOCK9chr1399508285-44827118032201046
ENST00000323482ACSS1chr2025011394-ENST00000339416DOCK9chr1399508285-32937118032921071
ENST00000323482ACSS1chr2025011394-ENST00000448493DOCK9chr1399508285-245971111042456451
ENST00000432802ACSS1chr2025011394-ENST00000376460DOCK9chr1399508285-5280150987840181046
ENST00000432802ACSS1chr2025011394-ENST00000339416DOCK9chr1399508285-4091150987840901071
ENST00000432802ACSS1chr2025011394-ENST00000448493DOCK9chr1399508285-3257150919023254451
ENST00000542618ACSS1chr2025011394-ENST00000376460DOCK9chr1399508285-43065352673044925
ENST00000542618ACSS1chr2025011394-ENST00000339416DOCK9chr1399508285-31175352673116949
ENST00000542618ACSS1chr2025011394-ENST00000448493DOCK9chr1399508285-22835359282280451

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000323482ENST00000376460ACSS1chr2025011394-DOCK9chr1399508285-0.0002180760.9997819
ENST00000323482ENST00000339416ACSS1chr2025011394-DOCK9chr1399508285-0.0018057720.9981943
ENST00000323482ENST00000448493ACSS1chr2025011394-DOCK9chr1399508285-0.072776730.9272232
ENST00000432802ENST00000376460ACSS1chr2025011394-DOCK9chr1399508285-0.00079970.9992003
ENST00000432802ENST00000339416ACSS1chr2025011394-DOCK9chr1399508285-0.0046901070.9953099
ENST00000432802ENST00000448493ACSS1chr2025011394-DOCK9chr1399508285-0.102739330.8972607
ENST00000542618ENST00000376460ACSS1chr2025011394-DOCK9chr1399508285-0.0002878350.99971217
ENST00000542618ENST00000339416ACSS1chr2025011394-DOCK9chr1399508285-0.0010277870.9989722
ENST00000542618ENST00000448493ACSS1chr2025011394-DOCK9chr1399508285-0.0152292730.9847707

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Fusion Genomic Features for ACSS1-DOCK9


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for ACSS1-DOCK9


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr20:25011394/chr13:99508285)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneACSS1chr20:25011394chr13:99508285ENST00000323482-31445_53210690.0Compositional biasNote=Poly-Ala
HgeneACSS1chr20:25011394chr13:99508285ENST00000432802-31245_53210576.0Compositional biasNote=Poly-Ala
HgeneACSS1chr20:25011394chr13:99508285ENST00000542618-21345_5389569.0Compositional biasNote=Poly-Ala
TgeneDOCK9chr20:25011394chr13:99508285ENST0000033941632541948_198212332094.0Coiled coilOntology_term=ECO:0000255
TgeneDOCK9chr20:25011394chr13:99508285ENST0000033941632542034_206712332094.0Coiled coilOntology_term=ECO:0000255
TgeneDOCK9chr20:25011394chr13:99508285ENST0000037646032571948_198212322069.0Coiled coilOntology_term=ECO:0000255
TgeneDOCK9chr20:25011394chr13:99508285ENST0000037646032572034_206712322069.0Coiled coilOntology_term=ECO:0000255
TgeneDOCK9chr20:25011394chr13:99508285ENST000004421730331948_198201254.0Coiled coilOntology_term=ECO:0000255
TgeneDOCK9chr20:25011394chr13:99508285ENST000004421730332034_206701254.0Coiled coilOntology_term=ECO:0000255
TgeneDOCK9chr20:25011394chr13:99508285ENST0000033941632541605_206912332094.0DomainDOCKER
TgeneDOCK9chr20:25011394chr13:99508285ENST0000037646032571605_206912322069.0DomainDOCKER
TgeneDOCK9chr20:25011394chr13:99508285ENST000004421730331605_206901254.0DomainDOCKER
TgeneDOCK9chr20:25011394chr13:99508285ENST00000442173033174_28101254.0DomainPH
TgeneDOCK9chr20:25011394chr13:99508285ENST00000442173033640_81801254.0DomainC2 DOCK-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneACSS1chr20:25011394chr13:99508285ENST00000323482-314417_419210690.0Nucleotide bindingATP
HgeneACSS1chr20:25011394chr13:99508285ENST00000323482-314441_446210690.0Nucleotide bindingATP
HgeneACSS1chr20:25011394chr13:99508285ENST00000432802-312417_419210576.0Nucleotide bindingATP
HgeneACSS1chr20:25011394chr13:99508285ENST00000432802-312441_446210576.0Nucleotide bindingATP
HgeneACSS1chr20:25011394chr13:99508285ENST00000542618-213417_41989569.0Nucleotide bindingATP
HgeneACSS1chr20:25011394chr13:99508285ENST00000542618-213441_44689569.0Nucleotide bindingATP
HgeneACSS1chr20:25011394chr13:99508285ENST00000323482-314224_227210690.0RegionCoenzyme A binding
HgeneACSS1chr20:25011394chr13:99508285ENST00000432802-312224_227210576.0RegionCoenzyme A binding
HgeneACSS1chr20:25011394chr13:99508285ENST00000542618-213224_22789569.0RegionCoenzyme A binding
TgeneDOCK9chr20:25011394chr13:99508285ENST000003394163254174_28112332094.0DomainPH
TgeneDOCK9chr20:25011394chr13:99508285ENST000003394163254640_81812332094.0DomainC2 DOCK-type
TgeneDOCK9chr20:25011394chr13:99508285ENST000003764603257174_28112322069.0DomainPH
TgeneDOCK9chr20:25011394chr13:99508285ENST000003764603257640_81812322069.0DomainC2 DOCK-type


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Fusion Gene Sequence for ACSS1-DOCK9


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>1535_1535_1_ACSS1-DOCK9_ACSS1_chr20_25011394_ENST00000323482_DOCK9_chr13_99508285_ENST00000339416_length(transcript)=3293nt_BP=711nt
GGCCCGCGGAGACTCCACGGGGCGCCCCGGGCGTGAGGCACCCACTCTGGGAGCACAGAGAGCTCAGGTAGCCTGCCTAGATGGCGGCGC
GCACCCTGGGCCGCGGCGTCGGGAGGCTGCTGGGCAGCCTGCGAGGGCTCTCGGGGCAGCCCGCGCGGCCGCCGTGCGGGGTGAGCGCGC
CGCGCAGGGCGGCCTCGGGACCCTCGGGCAGCGCTCCCGCAGTTGCAGCAGCAGCAGCACAGCCAGGCTCGTATCCCGCGCTGAGTGCAC
AGGCAGCCCGGGAGCCGGCCGCCTTCTGGGGGCCTCTGGCGCGGGACACTCTCGTGTGGGACACCCCCTACCACACCGTCTGGGACTGCG
ACTTCAGCACTGGCAAGATCGGCTGGTTCCTGGGAGGCCAGTTAAATGTCTCTGTCAACTGCTTGGACCAGCATGTTCGGAAGTCCCCCG
AGAGCGTTGCTTTGATCTGGGAGCGCGATGAGCCTGGAACGGAAGTGAGGATCACCTACAGGGAACTACTGGAGACCACGTGCCGCCTGG
CCAACACGCTGAAGAGGCATGGAGTCCACCGTGGGGACCGTGTTGCCATCTACATGCCCGTGTCCCCATTGGCTGTGGCAGCAATGCTGG
CCTGTGCCAGGATCGGAGCTGTCCACACAGTCATCTTTGCTGGCTTCAGTGCAGAGTCCTTGGCTGGGAGGATCAATGATGCTTCTCCAT
ATACAACCTCAACTCCAAACATCAACAGTGTGAGAAATGCTGATTCGAGAGGATCTCTCATAAGCACAGATTCGGGTAACAGCCTTCCAG
AAAGGAATAGTGAGAAGAGCAATTCCCTGGATAAGCACCAACAAAGTAGCACATTGGGAAATTCCGTGGTTCGCTGTGATAAACTTGACC
AGTCTGAGATTAAGAGCCTACTGATGTGTTTCCTCTACATCTTAAAGAGCATGTCTGATGATGCTTTGTTTACATATTGGAACAAGGCTT
CAACATCTGAACTTATGGATTTTTTTACAATATCTGAAGTCTGCCTGCACCAGTTCCAGTACATGGGGAAGCGATACATAGCCAGAACAG
GAATGATGCATGCCAGATTGCAGCAGCTGGGCAGCCTGGATAACTCTCTCACTTTTAACCACAGCTATGGCCACTCGGACGCAGATGTTC
TGCACCAGTCATTACTTGAAGCCAACATTGCTACTGAGGTTTGCCTGACAGCTCTGGACACGCTTTCTCTATTTACATTGGCGTTTAAGA
ACCAGCTCCTGGCCGACCATGGACATAATCCTCTCATGAAAAAAGTTTTTGATGTCTACCTGTGTTTTCTTCAAAAACATCAGTCTGAAA
CGGCTTTAAAAAATGTCTTCACTGCCTTAAGGTCCTTAATTTATAAGTTTCCCTCAACATTCTATGAAGGGAGAGCGGACATGTGTGCGG
CTCTGTGTTACGAGATTCTCAAGTGCTGTAACTCCAAGCTGAGCTCCATCAGGACGGAGGCCTCCCAGCTGCTCTACTTCCTGATGAGGA
ACAACTTTGATTACACTGGAAAGAAGTCCTTTGTCCGGACACATTTGCAAGTCATCATATCTGTCAGCCAGCTGATAGCAGACGTTGTTG
GCATTGGGGGAACCAGATTCCAGCAGTCCCTGTCCATCATCAACAACTGTGCCAACAGTGACCGGCTTATTAAGCACACCAGCTTCTCCT
CTGATGTGAAGGACTTAACCAAAAGGATACGCACGGTGCTAATGGCCACCGCCCAGATGAAGGAGCATGAGAACGACCCAGAGATGCTGG
TGGACCTCCAGTACAGCCTGGCCAAATCCTATGCCAGCACGCCCGAGCTCAGGAAGACGTGGCTCGACAGCATGGCCAGGATCCATGTCA
AAAATGGCGATCTCTCAGAGGCAGCAATGTGCTATGTCCACGTAACAGCCCTAGTGGCAGAATATCTCACACGGAAAGAAGCAGTCCAGT
GGGAGCCGCCCCTTCTCCCCCACAGCCATAGCGCCTGCCTGAGGAGGAGCCGGGGAGGCGTGTTTAGACAAGGATGCACCGCCTTCAGGG
TCATTACCCCAAACATCGACGAGGAGGCCTCCATGATGGAAGACGTGGGGATGCAGGATGTCCATTTCAACGAGGATGTGCTGATGGAGC
TCCTTGAGCAGTGCGCAGATGGACTCTGGAAAGCCGAGCGCTACGAGCTCATCGCCGACATCTACAAACTTATCATCCCCATTTATGAGA
AGCGGAGGGATTTTGAGAGGCTGGCCCATCTGTATGACACGCTGCACCGGGCCTACAGCAAAGTGACCGAGGTCATGCACTCGGGCCGCA
GGCTTCTGGGGACCTACTTCCGGGTAGCCTTCTTCGGGCAGGGATTCTTTGAAGATGAAGATGGAAAGGAGTATATTTACAAGGAACCCA
AACTCACACCGCTGTCGGAAATTTCTCAGAGACTCCTTAAACTGTACTCGGATAAATTTGGTTCTGAAAATGTCAAAATGATACAGGATT
CTGGCAAGGTCAACCCTAAGGATCTGGATTCTAAGTATGCATACATCCAGGTGACTCACGTCATCCCCTTCTTTGACGAAAAAGAGTTGC
AAGAAAGGAAAACAGAGTTTGAGAGATCCCACAACATCCGCCGCTTCATGTTTGAGATGCCATTTACGCAGACCGGGAAGAGGCAGGGCG
GGGTGGAAGAGCAGTGCAAACGGCGCACCATCCTGACAGCCATACACTGCTTCCCTTATGTGAAGAAGCGCATCCCTGTCATGTACCAGC
ACCACACTGACCTGAACCCCATCGAGGTGGCCATTGACGAGATGAGTAAGAAGGTGGCGGAGCTCCGGCAGCTGTGCTCCTCGGCCGAGG
TGGACATGATCAAACTGCAGCTCAAACTCCAGGGCAGCGTGAGTGTTCAGGTCAATGCTGGCCCACTAGCATATGCGCGAGCTTTCTTAG
ATGATACAAACACAAAGCGATATCCTGACAATAAAGTGAAGCTGCTTAAGGAAGTTTTCAGGCAATTTGTGGAAGCTTGCGGTCAAGCCT
TAGCGGTAAACGAACGTCTGATTAAAGAAGACCAGCTCGAGTATCAGGAAGAAATGAAAGCCAACTACAGGGAAATGGCGAAGGAGCTTT
CTGAAATCATGCATGAGCAGATCTGCCCCCTGGAGGAGAAGACGAGCGTCTTACCGAATTCCCTTCACATCTTCAACGCCATCAGTGGGA
CTCCAACAAGCACAATGGTTCACGGGATGACCAGCTCGTCTTCGGTCGTGTGA

>1535_1535_1_ACSS1-DOCK9_ACSS1_chr20_25011394_ENST00000323482_DOCK9_chr13_99508285_ENST00000339416_length(amino acids)=1071AA_BP=210
MAARTLGRGVGRLLGSLRGLSGQPARPPCGVSAPRRAASGPSGSAPAVAAAAAQPGSYPALSAQAAREPAAFWGPLARDTLVWDTPYHTV
WDCDFSTGKIGWFLGGQLNVSVNCLDQHVRKSPESVALIWERDEPGTEVRITYRELLETTCRLANTLKRHGVHRGDRVAIYMPVSPLAVA
AMLACARIGAVHTVIFAGFSAESLAGRINDASPYTTSTPNINSVRNADSRGSLISTDSGNSLPERNSEKSNSLDKHQQSSTLGNSVVRCD
KLDQSEIKSLLMCFLYILKSMSDDALFTYWNKASTSELMDFFTISEVCLHQFQYMGKRYIARTGMMHARLQQLGSLDNSLTFNHSYGHSD
ADVLHQSLLEANIATEVCLTALDTLSLFTLAFKNQLLADHGHNPLMKKVFDVYLCFLQKHQSETALKNVFTALRSLIYKFPSTFYEGRAD
MCAALCYEILKCCNSKLSSIRTEASQLLYFLMRNNFDYTGKKSFVRTHLQVIISVSQLIADVVGIGGTRFQQSLSIINNCANSDRLIKHT
SFSSDVKDLTKRIRTVLMATAQMKEHENDPEMLVDLQYSLAKSYASTPELRKTWLDSMARIHVKNGDLSEAAMCYVHVTALVAEYLTRKE
AVQWEPPLLPHSHSACLRRSRGGVFRQGCTAFRVITPNIDEEASMMEDVGMQDVHFNEDVLMELLEQCADGLWKAERYELIADIYKLIIP
IYEKRRDFERLAHLYDTLHRAYSKVTEVMHSGRRLLGTYFRVAFFGQGFFEDEDGKEYIYKEPKLTPLSEISQRLLKLYSDKFGSENVKM
IQDSGKVNPKDLDSKYAYIQVTHVIPFFDEKELQERKTEFERSHNIRRFMFEMPFTQTGKRQGGVEEQCKRRTILTAIHCFPYVKKRIPV
MYQHHTDLNPIEVAIDEMSKKVAELRQLCSSAEVDMIKLQLKLQGSVSVQVNAGPLAYARAFLDDTNTKRYPDNKVKLLKEVFRQFVEAC
GQALAVNERLIKEDQLEYQEEMKANYREMAKELSEIMHEQICPLEEKTSVLPNSLHIFNAISGTPTSTMVHGMTSSSSVVX

--------------------------------------------------------------
>1535_1535_2_ACSS1-DOCK9_ACSS1_chr20_25011394_ENST00000323482_DOCK9_chr13_99508285_ENST00000376460_length(transcript)=4482nt_BP=711nt
GGCCCGCGGAGACTCCACGGGGCGCCCCGGGCGTGAGGCACCCACTCTGGGAGCACAGAGAGCTCAGGTAGCCTGCCTAGATGGCGGCGC
GCACCCTGGGCCGCGGCGTCGGGAGGCTGCTGGGCAGCCTGCGAGGGCTCTCGGGGCAGCCCGCGCGGCCGCCGTGCGGGGTGAGCGCGC
CGCGCAGGGCGGCCTCGGGACCCTCGGGCAGCGCTCCCGCAGTTGCAGCAGCAGCAGCACAGCCAGGCTCGTATCCCGCGCTGAGTGCAC
AGGCAGCCCGGGAGCCGGCCGCCTTCTGGGGGCCTCTGGCGCGGGACACTCTCGTGTGGGACACCCCCTACCACACCGTCTGGGACTGCG
ACTTCAGCACTGGCAAGATCGGCTGGTTCCTGGGAGGCCAGTTAAATGTCTCTGTCAACTGCTTGGACCAGCATGTTCGGAAGTCCCCCG
AGAGCGTTGCTTTGATCTGGGAGCGCGATGAGCCTGGAACGGAAGTGAGGATCACCTACAGGGAACTACTGGAGACCACGTGCCGCCTGG
CCAACACGCTGAAGAGGCATGGAGTCCACCGTGGGGACCGTGTTGCCATCTACATGCCCGTGTCCCCATTGGCTGTGGCAGCAATGCTGG
CCTGTGCCAGGATCGGAGCTGTCCACACAGTCATCTTTGCTGGCTTCAGTGCAGAGTCCTTGGCTGGGAGGATCAATGATGCTTCTCCAT
ATACAACCTCAACTCCAAACATCAACAGTGTGAGAAATGCTGATTCGAGAGGATCTCTCATAAGCACAGATTCGGGTAACAGCCTTCCAG
AAAGGAATAGTGAGAAGAGCAATTCCCTGGATAAGCACCAACAAAGTAGCACATTGGGAAATTCCGTGGTTCGCTGTGATAAACTTGACC
AGTCTGAGATTAAGAGCCTACTGATGTGTTTCCTCTACATCTTAAAGAGCATGTCTGATGATGCTTTGTTTACATATTGGAACAAGGCTT
CAACATCTGAACTTATGGATTTTTTTACAATATCTGAAGTCTGCCTGCACCAGTTCCAGTACATGGGGAAGCGATACATAGCCAGAACAG
GAATGATGCATGCCAGATTGCAGCAGCTGGGCAGCCTGGATAACTCTCTCACTTTTAACCACAGCTATGGCCACTCGGACGCAGATGTTC
TGCACCAGTCATTACTTGAAGCCAACATTGCTACTGAGGTTTGCCTGACAGCTCTGGACACGCTTTCTCTATTTACATTGGCGTTTAAGA
ACCAGCTCCTGGCCGACCATGGACATAATCCTCTCATGAAAAAAGTTTTTGATGTCTACCTGTGTTTTCTTCAAAAACATCAGTCTGAAA
CGGCTTTAAAAAATGTCTTCACTGCCTTAAGGTCCTTAATTTATAAGTTTCCCTCAACATTCTATGAAGGGAGAGCGGACATGTGTGCGG
CTCTGTGTTACGAGATTCTCAAGTGCTGTAACTCCAAGCTGAGCTCCATCAGGACGGAGGCCTCCCAGCTGCTCTACTTCCTGATGAGGA
ACAACTTTGATTACACTGGAAAGAAGTCCTTTGTCCGGACACATTTGCAAGTCATCATATCTGTCAGCCAGCTGATAGCAGACGTTGTTG
GCATTGGGGGAACCAGATTCCAGCAGTCCCTGTCCATCATCAACAACTGTGCCAACAGTGACCGGCTTATTAAGCACACCAGCTTCTCCT
CTGATGTGAAGGACTTAACCAAAAGGATACGCACGGTGCTAATGGCCACCGCCCAGATGAAGGAGCATGAGAACGACCCAGAGATGCTGG
TGGACCTCCAGTACAGCCTGGCCAAATCCTATGCCAGCACGCCCGAGCTCAGGAAGACGTGGCTCGACAGCATGGCCAGGATCCATGTCA
AAAATGGCGATCTCTCAGAGGCAGCAATGTGCTATGTCCACGTAACAGCCCTAGTGGCAGAATATCTCACACGGAAAGAAGCAGTCCAGT
GGGAGCCGCCCCTTCTCCCCCACAGCCATAGCGCCTGCCTGAGGAGGAGCCGGGGAGGCGTGTTTAGACAAGGATGCACCGCCTTCAGGG
TCATTACCCCAAACATCGACGAGGAGGCCTCCATGATGGAAGACGTGGGGATGCAGGATGTCCATTTCAACGAGGATGTGCTGATGGAGC
TCCTTGAGCAGTGCGCAGATGGACTCTGGAAAGCCGAGCGCTACGAGCTCATCGCCGACATCTACAAACTTATCATCCCCATTTATGAGA
AGCGGAGGGATTTTGAGAGGCTGGCCCATCTGTATGACACGCTGCACCGGGCCTACAGCAAAGTGACCGAGGTCATGCACTCGGGCCGCA
GGCTTCTGGGGACCTACTTCCGGGTAGCCTTCTTCGGGCAGGCAGCGCAATACCAGTTTACAGACAGTGAAACAGATGTGGAGGGATTCT
TTGAAGATGAAGATGGAAAGGAGTATATTTACAAGGAACCCAAACTCACACCGCTGTCGGAAATTTCTCAGAGACTCCTTAAACTGTACT
CGGATAAATTTGGTTCTGAAAATGTCAAAATGATACAGGATTCTGGCAAGGTCAACCCTAAGGATCTGGATTCTAAGTATGCATACATCC
AGGTGACTCACGTCATCCCCTTCTTTGACGAAAAAGAGTTGCAAGAAAGGAAAACAGAGTTTGAGAGATCCCACAACATCCGCCGCTTCA
TGTTTGAGATGCCATTTACGCAGACCGGGAAGAGGCAGGGCGGGGTGGAAGAGCAGTGCAAACGGCGCACCATCCTGACAGCCATACACT
GCTTCCCTTATGTGAAGAAGCGCATCCCTGTCATGTACCAGCACCACACTGACCTGAACCCCATCGAGGTGGCCATTGACGAGATGAGTA
AGAAGGTGGCGGAGCTCCGGCAGCTGTGCTCCTCGGCCGAGGTGGACATGATCAAACTGCAGCTCAAACTCCAGGGCAGCGTGAGTGTTC
AGGTCAATGCTGGCCCACTAGCATATGCGCGAGCTTTCTTAGATGATACAAACACAAAGCGATATCCTGACAATAAAGTGAAGCTGCTTA
AGGAAGTTTTCAGGCAATTTGTGGAAGCTTGCGGTCAAGCCTTAGCGGTAAACGAACGTCTGATTAAAGAAGACCAGCTCGAGTATCAGG
AAGAAATGAAAGCCAACTACAGGGAAATGGCGAAGGAGCTTTCTGAAATCATGCATGAGCAGCTGGGATGATCTGCCCCCTGGAGGAGAA
GACGAGCGTCTTACCGAATTCCCTTCACATCTTCAACGCCATCAGTGGGACTCCAACAAGCACAATGGTTCACGGGATGACCAGCTCGTC
TTCGGTCGTGTGATTACATCTCATGGCCCGTGTGTGGGGACTTGCTTTGTCATTTGCAAACTCAGGATGCTTTCCAAAGCCAATCACTGG
GGAGACCGAGCACAGGGAGGACCAAGGGGAAGGGGAGAGAAAGGAAATAAAGAACAACGTTATTTCTTAACAGACTTTCTATAGGAGTTG
TAAGAAGGTGCACATATTTTTTTAAATCTCACTGGCAATATTCAAAGTTTTCATTGTGTCTTAACAAAGGTGTGGTAGACACTCTTGAGC
TGGACTTAGATTTTATTCTTCCTTGCAGAGTAGTGTTAGAATAGATGGCCTACAGAAAAAAAAGGTTCTGGGATCTACATGGCAGGGAGG
GCTGCACTGACATTGATGCCTGGGGGACCTTTTGCCTCGAGGCTGAGCTGGAAAATCTTGAAAATATTTTTTTTTTCCTGTGGCACATTC
AGGTTGAATACAAGAACTATTTTTGTGACTAGTTTTTGATGACCTAAGGGAACTGACCATTGTAATTTTTGTACCAGTGAACCAGGAGAT
TTAGTGCTTTTATATTCATTTCCTTGCATTTAAGAAAATATGAAAGCTTAAGGAATTATGTGAGCTTAAAACTAGTCAAGCAGTTTAGAA
CCAAAGGCCTATATTAATAACCGCAACTATGCTGAAAAGTACAAAGTAGTACAGTATATTGTTATGTACATATCATTGTTAATACAGTCC
TGGCATTCTGTACATATATGTATTACATTTCTACATTTTTAATACTCACATGGGCTTATGCATTAAGTTTAATTGTGATAAATTTGTGCT
GTTCCAGTATATGCAATACACTTTAATGTTTTATTCTTGTACATAAAAATGTGCAATATGGAGATGTATACAGTCTTTACTATATTAGGT
TTATAAACAGTTTTAAGAATTTCATCCTTTTGCCAAAATGGTGGAGTATGTAATTGGTAAATCATAAATCCTGTGGTGAATGGTGGTGTA
CTTTAAAGCTGTCACCATGTTATATTTTCTTTTAAGACTTTAATTTAGTAATTTTATATTTGGGAAAATAAAGGTTTTTAATTTTATTTA
ACTGGAATCACTGCCCTGCTGTAATTAAACATTCTGTACCACATCTGTATTAAAAAGACATTGCTGACCATT

>1535_1535_2_ACSS1-DOCK9_ACSS1_chr20_25011394_ENST00000323482_DOCK9_chr13_99508285_ENST00000376460_length(amino acids)=1046AA_BP=210
MAARTLGRGVGRLLGSLRGLSGQPARPPCGVSAPRRAASGPSGSAPAVAAAAAQPGSYPALSAQAAREPAAFWGPLARDTLVWDTPYHTV
WDCDFSTGKIGWFLGGQLNVSVNCLDQHVRKSPESVALIWERDEPGTEVRITYRELLETTCRLANTLKRHGVHRGDRVAIYMPVSPLAVA
AMLACARIGAVHTVIFAGFSAESLAGRINDASPYTTSTPNINSVRNADSRGSLISTDSGNSLPERNSEKSNSLDKHQQSSTLGNSVVRCD
KLDQSEIKSLLMCFLYILKSMSDDALFTYWNKASTSELMDFFTISEVCLHQFQYMGKRYIARTGMMHARLQQLGSLDNSLTFNHSYGHSD
ADVLHQSLLEANIATEVCLTALDTLSLFTLAFKNQLLADHGHNPLMKKVFDVYLCFLQKHQSETALKNVFTALRSLIYKFPSTFYEGRAD
MCAALCYEILKCCNSKLSSIRTEASQLLYFLMRNNFDYTGKKSFVRTHLQVIISVSQLIADVVGIGGTRFQQSLSIINNCANSDRLIKHT
SFSSDVKDLTKRIRTVLMATAQMKEHENDPEMLVDLQYSLAKSYASTPELRKTWLDSMARIHVKNGDLSEAAMCYVHVTALVAEYLTRKE
AVQWEPPLLPHSHSACLRRSRGGVFRQGCTAFRVITPNIDEEASMMEDVGMQDVHFNEDVLMELLEQCADGLWKAERYELIADIYKLIIP
IYEKRRDFERLAHLYDTLHRAYSKVTEVMHSGRRLLGTYFRVAFFGQAAQYQFTDSETDVEGFFEDEDGKEYIYKEPKLTPLSEISQRLL
KLYSDKFGSENVKMIQDSGKVNPKDLDSKYAYIQVTHVIPFFDEKELQERKTEFERSHNIRRFMFEMPFTQTGKRQGGVEEQCKRRTILT
AIHCFPYVKKRIPVMYQHHTDLNPIEVAIDEMSKKVAELRQLCSSAEVDMIKLQLKLQGSVSVQVNAGPLAYARAFLDDTNTKRYPDNKV
KLLKEVFRQFVEACGQALAVNERLIKEDQLEYQEEMKANYREMAKELSEIMHEQLG

--------------------------------------------------------------
>1535_1535_3_ACSS1-DOCK9_ACSS1_chr20_25011394_ENST00000323482_DOCK9_chr13_99508285_ENST00000448493_length(transcript)=2459nt_BP=711nt
GGCCCGCGGAGACTCCACGGGGCGCCCCGGGCGTGAGGCACCCACTCTGGGAGCACAGAGAGCTCAGGTAGCCTGCCTAGATGGCGGCGC
GCACCCTGGGCCGCGGCGTCGGGAGGCTGCTGGGCAGCCTGCGAGGGCTCTCGGGGCAGCCCGCGCGGCCGCCGTGCGGGGTGAGCGCGC
CGCGCAGGGCGGCCTCGGGACCCTCGGGCAGCGCTCCCGCAGTTGCAGCAGCAGCAGCACAGCCAGGCTCGTATCCCGCGCTGAGTGCAC
AGGCAGCCCGGGAGCCGGCCGCCTTCTGGGGGCCTCTGGCGCGGGACACTCTCGTGTGGGACACCCCCTACCACACCGTCTGGGACTGCG
ACTTCAGCACTGGCAAGATCGGCTGGTTCCTGGGAGGCCAGTTAAATGTCTCTGTCAACTGCTTGGACCAGCATGTTCGGAAGTCCCCCG
AGAGCGTTGCTTTGATCTGGGAGCGCGATGAGCCTGGAACGGAAGTGAGGATCACCTACAGGGAACTACTGGAGACCACGTGCCGCCTGG
CCAACACGCTGAAGAGGCATGGAGTCCACCGTGGGGACCGTGTTGCCATCTACATGCCCGTGTCCCCATTGGCTGTGGCAGCAATGCTGG
CCTGTGCCAGGATCGGAGCTGTCCACACAGTCATCTTTGCTGGCTTCAGTGCAGAGTCCTTGGCTGGGAGGATCAATGATGCTTCTCCAT
ATACAACCTCAACTCCAAACATCAACAGTGTGAGAAATGCTGATTCGAGAGGATCTCTCATAAGCACAGATTCGGGTAACAGCCTTCCAG
AAAGGAATAGTGAGAAGAGCAATTCCCTGGATAAGCACCAACAAAGTAGCACATTGGGAAATTCCGTGGTTCGCTGTGATAAACTTGACC
AGTCTGAGATTAAGAGCCTACTGATGTGTTTCCTCTACATCTTAAAGAGCATGTCTGATGATGCTTTGTTTACATATTGGAACAAGGCTT
CAACATCTGAACTTATGGATTTTTTTACAATATCTGAAGTCTGCCTGCACCAGTTCCAGTACATGGGGAAGCGATACATAGCCAGTTTAA
CAAAGTGTGTGGCTCTTCTCCTTCCTGCTTGGAACAGGAATGATGCATGCCAGATTGCAGCAGCTGGGCAGCCTGGATAACTCTCTCACT
TTTAACCACAGCTATGGCCACTCGGACGCAGATGTTCTGCACCAGTCATTACTTGAAGCCAACATTGCTACTGAGGTTTGCCTGACAGCT
CTGGACACGCTTTCTCTATTTACATTGGCGTTTAAGAACCAGCTCCTGGCCGACCATGGACATAATCCTCTCATGAAAAAAGTTTTTGAT
GTCTACCTGTGTTTTCTTCAAAAACATCAGTCTGAAACGGCTTTAAAAAATGTCTTCACTGCCTTAAGGTCCTTAATTTATAAGTTTCCC
TCAACATTCTATGAAGGGAGAGCGGACATGTGTGCGGCTCTGTGTTACGAGATTCTCAAGTGCTGTAACTCCAAGCTGAGCTCCATCAGG
ACGGAGGCCTCCCAGCTGCTCTACTTCCTGATGAGGAACAACTTTGATTACACTGGAAAGAAGTCCTTTGTCCGGACACATTTGCAAGTC
ATCATATCTGTCAGCCAGCTGATAGCAGACGTTGTTGGCATTGGGGGAACCAGATTCCAGCAGTCCCTGTCCATCATCAACAACTGTGCC
AACAGTGACCGGCTTATTAAGCACACCAGCTTCTCCTCTGATGTGAAGGACTTAACCAAAAGGATACGCACGGTGCTAATGGCCACCGCC
CAGATGAAGGAGCATGAGAACGACCCAGAGATGCTGGTGGACCTCCAGTACAGCCTGGCCAAATCCTATGCCAGCACGCCCGAGCTCAGG
AAGACGTGGCTCGACAGCATGGCCAGGATCCATGTCAAAAATGGCGATCTCTCAGAGGCAGCAATGTGCTATGTCCACGTAACAGCCCTA
GTGGCAGAATATCTCACACGGAAAGAAGCAGTCCAGTGGGAGCCGCCCCTTCTCCCCCACAGCCATAGCGCCTGCCTGAGGAGGAGCCGG
GGAGGCGTGTTTAGACAAGGATGCACCGCCTTCAGGGTCATTACCCCAAACATCGACGAGGAGGCCTCCATGATGGAAGACGTGGGGATG
CAGGATGTCCATTTCAACGAGGATGTGCTGATGGAGCTCCTTGAGCAGTGCGCAGATGGACTCTGGAAAGCCGAGCGCTACGAGCTCATC
GCCGACATCTACAAACTTATCATCCCCATTTATGAGAAGCGGAGGGATTTTGAGAGGCTGGCCCATCTGTATGACACGCTGCACCGGGCC
TACAGCAAAGTGACCGAGGTCATGCACTCGGGCCGCAGGCTTCTGGGGACCTACTTCCGGGTAGCCTTCTTCGGGCAGGTGAGCCTCCTG
TCCATTCTGCAGACTGTCCTAAGTCCTTT

>1535_1535_3_ACSS1-DOCK9_ACSS1_chr20_25011394_ENST00000323482_DOCK9_chr13_99508285_ENST00000448493_length(amino acids)=451AA_BP=
MLGTGMMHARLQQLGSLDNSLTFNHSYGHSDADVLHQSLLEANIATEVCLTALDTLSLFTLAFKNQLLADHGHNPLMKKVFDVYLCFLQK
HQSETALKNVFTALRSLIYKFPSTFYEGRADMCAALCYEILKCCNSKLSSIRTEASQLLYFLMRNNFDYTGKKSFVRTHLQVIISVSQLI
ADVVGIGGTRFQQSLSIINNCANSDRLIKHTSFSSDVKDLTKRIRTVLMATAQMKEHENDPEMLVDLQYSLAKSYASTPELRKTWLDSMA
RIHVKNGDLSEAAMCYVHVTALVAEYLTRKEAVQWEPPLLPHSHSACLRRSRGGVFRQGCTAFRVITPNIDEEASMMEDVGMQDVHFNED
VLMELLEQCADGLWKAERYELIADIYKLIIPIYEKRRDFERLAHLYDTLHRAYSKVTEVMHSGRRLLGTYFRVAFFGQVSLLSILQTVLS
P

--------------------------------------------------------------
>1535_1535_4_ACSS1-DOCK9_ACSS1_chr20_25011394_ENST00000432802_DOCK9_chr13_99508285_ENST00000339416_length(transcript)=4091nt_BP=1509nt
AAAAGGAAAACGAGGCACCGAGAAGTTAAGGAACTTGCTCAAGGTCACAGAGTTTGAACTCAGGCTACAGATGCTGCAGCAACTGGAGAA
AGTCCTCATCGCCCCATATCACCCACCACCGACCCCCAGCAGGACGTGACCCCCGCCAGGACGGAGGCCGGCAGCTGGGGGGCTGGAGCA
TGGGACCCAGAACACGGACTCAGGCTTGCGCAGCCTCCTGGCTTCTAGGCGGGAGCCTAGAAAGGCGCCAGCCCCTTTCGCGTGCTGCTG
AGACTCCAGGGGTGGGGTTCACTCTCAGGGGCGCACAAAGGCATGAAAACCTTGGCTTCAGCCTCTGAGATGCGGAACTGACCGACCTAT
TGTCTTGGGACCCACCAGTGCGCTTGGGTGCACCAGCCCCCTTAACGTTGGTGCCGGCTCCCTCCCGGCTCCTCCCCATCCCAGAGGGTC
CCCTCGCCCCAGGCCCTGAGCCTGCGTCCTGGGGTCCTGGGCCGCACGTGCCTCTGGCAGCTCGAAGAAGCTGTCGGGGCTTGCAGGAGA
GCGTGCAAACTGAAACCAAAACAGGCCGACTCGAGGAACATCCGGGTGGGACCGCAGACTCACCGGAGCGCAGCGCCTGGGCCAGGGCCT
GGGACCCTGCTCCGCCCCGCGCTCCCCTGCACCCCTTCCCCACGCTGCTCCCCTCTTCCTAAGCGGCCCCCCCTCTCCCGGGCAGCAGAA
GAAGGGGTGGGACCCGGGCGGGCTCCGGGAGGGGGCCCTGGAGGAATGGATGGTGGCGGAAGGGCGGAGCAGGGGCGGGGCCCGCGGAGA
CTCCACGGGGCGCCCCGGGCGTGAGGCACCCACTCTGGGAGCACAGAGAGCTCAGGTAGCCTGCCTAGATGGCGGCGCGCACCCTGGGCC
GCGGCGTCGGGAGGCTGCTGGGCAGCCTGCGAGGGCTCTCGGGGCAGCCCGCGCGGCCGCCGTGCGGGGTGAGCGCGCCGCGCAGGGCGG
CCTCGGGACCCTCGGGCAGCGCTCCCGCAGTTGCAGCAGCAGCAGCACAGCCAGGCTCGTATCCCGCGCTGAGTGCACAGGCAGCCCGGG
AGCCGGCCGCCTTCTGGGGGCCTCTGGCGCGGGACACTCTCGTGTGGGACACCCCCTACCACACCGTCTGGGACTGCGACTTCAGCACTG
GCAAGATCGGCTGGTTCCTGGGAGGCCAGTTAAATGTCTCTGTCAACTGCTTGGACCAGCATGTTCGGAAGTCCCCCGAGAGCGTTGCTT
TGATCTGGGAGCGCGATGAGCCTGGAACGGAAGTGAGGATCACCTACAGGGAACTACTGGAGACCACGTGCCGCCTGGCCAACACGCTGA
AGAGGCATGGAGTCCACCGTGGGGACCGTGTTGCCATCTACATGCCCGTGTCCCCATTGGCTGTGGCAGCAATGCTGGCCTGTGCCAGGA
TCGGAGCTGTCCACACAGTCATCTTTGCTGGCTTCAGTGCAGAGTCCTTGGCTGGGAGGATCAATGATGCTTCTCCATATACAACCTCAA
CTCCAAACATCAACAGTGTGAGAAATGCTGATTCGAGAGGATCTCTCATAAGCACAGATTCGGGTAACAGCCTTCCAGAAAGGAATAGTG
AGAAGAGCAATTCCCTGGATAAGCACCAACAAAGTAGCACATTGGGAAATTCCGTGGTTCGCTGTGATAAACTTGACCAGTCTGAGATTA
AGAGCCTACTGATGTGTTTCCTCTACATCTTAAAGAGCATGTCTGATGATGCTTTGTTTACATATTGGAACAAGGCTTCAACATCTGAAC
TTATGGATTTTTTTACAATATCTGAAGTCTGCCTGCACCAGTTCCAGTACATGGGGAAGCGATACATAGCCAGAACAGGAATGATGCATG
CCAGATTGCAGCAGCTGGGCAGCCTGGATAACTCTCTCACTTTTAACCACAGCTATGGCCACTCGGACGCAGATGTTCTGCACCAGTCAT
TACTTGAAGCCAACATTGCTACTGAGGTTTGCCTGACAGCTCTGGACACGCTTTCTCTATTTACATTGGCGTTTAAGAACCAGCTCCTGG
CCGACCATGGACATAATCCTCTCATGAAAAAAGTTTTTGATGTCTACCTGTGTTTTCTTCAAAAACATCAGTCTGAAACGGCTTTAAAAA
ATGTCTTCACTGCCTTAAGGTCCTTAATTTATAAGTTTCCCTCAACATTCTATGAAGGGAGAGCGGACATGTGTGCGGCTCTGTGTTACG
AGATTCTCAAGTGCTGTAACTCCAAGCTGAGCTCCATCAGGACGGAGGCCTCCCAGCTGCTCTACTTCCTGATGAGGAACAACTTTGATT
ACACTGGAAAGAAGTCCTTTGTCCGGACACATTTGCAAGTCATCATATCTGTCAGCCAGCTGATAGCAGACGTTGTTGGCATTGGGGGAA
CCAGATTCCAGCAGTCCCTGTCCATCATCAACAACTGTGCCAACAGTGACCGGCTTATTAAGCACACCAGCTTCTCCTCTGATGTGAAGG
ACTTAACCAAAAGGATACGCACGGTGCTAATGGCCACCGCCCAGATGAAGGAGCATGAGAACGACCCAGAGATGCTGGTGGACCTCCAGT
ACAGCCTGGCCAAATCCTATGCCAGCACGCCCGAGCTCAGGAAGACGTGGCTCGACAGCATGGCCAGGATCCATGTCAAAAATGGCGATC
TCTCAGAGGCAGCAATGTGCTATGTCCACGTAACAGCCCTAGTGGCAGAATATCTCACACGGAAAGAAGCAGTCCAGTGGGAGCCGCCCC
TTCTCCCCCACAGCCATAGCGCCTGCCTGAGGAGGAGCCGGGGAGGCGTGTTTAGACAAGGATGCACCGCCTTCAGGGTCATTACCCCAA
ACATCGACGAGGAGGCCTCCATGATGGAAGACGTGGGGATGCAGGATGTCCATTTCAACGAGGATGTGCTGATGGAGCTCCTTGAGCAGT
GCGCAGATGGACTCTGGAAAGCCGAGCGCTACGAGCTCATCGCCGACATCTACAAACTTATCATCCCCATTTATGAGAAGCGGAGGGATT
TTGAGAGGCTGGCCCATCTGTATGACACGCTGCACCGGGCCTACAGCAAAGTGACCGAGGTCATGCACTCGGGCCGCAGGCTTCTGGGGA
CCTACTTCCGGGTAGCCTTCTTCGGGCAGGGATTCTTTGAAGATGAAGATGGAAAGGAGTATATTTACAAGGAACCCAAACTCACACCGC
TGTCGGAAATTTCTCAGAGACTCCTTAAACTGTACTCGGATAAATTTGGTTCTGAAAATGTCAAAATGATACAGGATTCTGGCAAGGTCA
ACCCTAAGGATCTGGATTCTAAGTATGCATACATCCAGGTGACTCACGTCATCCCCTTCTTTGACGAAAAAGAGTTGCAAGAAAGGAAAA
CAGAGTTTGAGAGATCCCACAACATCCGCCGCTTCATGTTTGAGATGCCATTTACGCAGACCGGGAAGAGGCAGGGCGGGGTGGAAGAGC
AGTGCAAACGGCGCACCATCCTGACAGCCATACACTGCTTCCCTTATGTGAAGAAGCGCATCCCTGTCATGTACCAGCACCACACTGACC
TGAACCCCATCGAGGTGGCCATTGACGAGATGAGTAAGAAGGTGGCGGAGCTCCGGCAGCTGTGCTCCTCGGCCGAGGTGGACATGATCA
AACTGCAGCTCAAACTCCAGGGCAGCGTGAGTGTTCAGGTCAATGCTGGCCCACTAGCATATGCGCGAGCTTTCTTAGATGATACAAACA
CAAAGCGATATCCTGACAATAAAGTGAAGCTGCTTAAGGAAGTTTTCAGGCAATTTGTGGAAGCTTGCGGTCAAGCCTTAGCGGTAAACG
AACGTCTGATTAAAGAAGACCAGCTCGAGTATCAGGAAGAAATGAAAGCCAACTACAGGGAAATGGCGAAGGAGCTTTCTGAAATCATGC
ATGAGCAGATCTGCCCCCTGGAGGAGAAGACGAGCGTCTTACCGAATTCCCTTCACATCTTCAACGCCATCAGTGGGACTCCAACAAGCA
CAATGGTTCACGGGATGACCAGCTCGTCTTCGGTCGTGTGA

>1535_1535_4_ACSS1-DOCK9_ACSS1_chr20_25011394_ENST00000432802_DOCK9_chr13_99508285_ENST00000339416_length(amino acids)=1071AA_BP=210
MAARTLGRGVGRLLGSLRGLSGQPARPPCGVSAPRRAASGPSGSAPAVAAAAAQPGSYPALSAQAAREPAAFWGPLARDTLVWDTPYHTV
WDCDFSTGKIGWFLGGQLNVSVNCLDQHVRKSPESVALIWERDEPGTEVRITYRELLETTCRLANTLKRHGVHRGDRVAIYMPVSPLAVA
AMLACARIGAVHTVIFAGFSAESLAGRINDASPYTTSTPNINSVRNADSRGSLISTDSGNSLPERNSEKSNSLDKHQQSSTLGNSVVRCD
KLDQSEIKSLLMCFLYILKSMSDDALFTYWNKASTSELMDFFTISEVCLHQFQYMGKRYIARTGMMHARLQQLGSLDNSLTFNHSYGHSD
ADVLHQSLLEANIATEVCLTALDTLSLFTLAFKNQLLADHGHNPLMKKVFDVYLCFLQKHQSETALKNVFTALRSLIYKFPSTFYEGRAD
MCAALCYEILKCCNSKLSSIRTEASQLLYFLMRNNFDYTGKKSFVRTHLQVIISVSQLIADVVGIGGTRFQQSLSIINNCANSDRLIKHT
SFSSDVKDLTKRIRTVLMATAQMKEHENDPEMLVDLQYSLAKSYASTPELRKTWLDSMARIHVKNGDLSEAAMCYVHVTALVAEYLTRKE
AVQWEPPLLPHSHSACLRRSRGGVFRQGCTAFRVITPNIDEEASMMEDVGMQDVHFNEDVLMELLEQCADGLWKAERYELIADIYKLIIP
IYEKRRDFERLAHLYDTLHRAYSKVTEVMHSGRRLLGTYFRVAFFGQGFFEDEDGKEYIYKEPKLTPLSEISQRLLKLYSDKFGSENVKM
IQDSGKVNPKDLDSKYAYIQVTHVIPFFDEKELQERKTEFERSHNIRRFMFEMPFTQTGKRQGGVEEQCKRRTILTAIHCFPYVKKRIPV
MYQHHTDLNPIEVAIDEMSKKVAELRQLCSSAEVDMIKLQLKLQGSVSVQVNAGPLAYARAFLDDTNTKRYPDNKVKLLKEVFRQFVEAC
GQALAVNERLIKEDQLEYQEEMKANYREMAKELSEIMHEQICPLEEKTSVLPNSLHIFNAISGTPTSTMVHGMTSSSSVVX

--------------------------------------------------------------
>1535_1535_5_ACSS1-DOCK9_ACSS1_chr20_25011394_ENST00000432802_DOCK9_chr13_99508285_ENST00000376460_length(transcript)=5280nt_BP=1509nt
AAAAGGAAAACGAGGCACCGAGAAGTTAAGGAACTTGCTCAAGGTCACAGAGTTTGAACTCAGGCTACAGATGCTGCAGCAACTGGAGAA
AGTCCTCATCGCCCCATATCACCCACCACCGACCCCCAGCAGGACGTGACCCCCGCCAGGACGGAGGCCGGCAGCTGGGGGGCTGGAGCA
TGGGACCCAGAACACGGACTCAGGCTTGCGCAGCCTCCTGGCTTCTAGGCGGGAGCCTAGAAAGGCGCCAGCCCCTTTCGCGTGCTGCTG
AGACTCCAGGGGTGGGGTTCACTCTCAGGGGCGCACAAAGGCATGAAAACCTTGGCTTCAGCCTCTGAGATGCGGAACTGACCGACCTAT
TGTCTTGGGACCCACCAGTGCGCTTGGGTGCACCAGCCCCCTTAACGTTGGTGCCGGCTCCCTCCCGGCTCCTCCCCATCCCAGAGGGTC
CCCTCGCCCCAGGCCCTGAGCCTGCGTCCTGGGGTCCTGGGCCGCACGTGCCTCTGGCAGCTCGAAGAAGCTGTCGGGGCTTGCAGGAGA
GCGTGCAAACTGAAACCAAAACAGGCCGACTCGAGGAACATCCGGGTGGGACCGCAGACTCACCGGAGCGCAGCGCCTGGGCCAGGGCCT
GGGACCCTGCTCCGCCCCGCGCTCCCCTGCACCCCTTCCCCACGCTGCTCCCCTCTTCCTAAGCGGCCCCCCCTCTCCCGGGCAGCAGAA
GAAGGGGTGGGACCCGGGCGGGCTCCGGGAGGGGGCCCTGGAGGAATGGATGGTGGCGGAAGGGCGGAGCAGGGGCGGGGCCCGCGGAGA
CTCCACGGGGCGCCCCGGGCGTGAGGCACCCACTCTGGGAGCACAGAGAGCTCAGGTAGCCTGCCTAGATGGCGGCGCGCACCCTGGGCC
GCGGCGTCGGGAGGCTGCTGGGCAGCCTGCGAGGGCTCTCGGGGCAGCCCGCGCGGCCGCCGTGCGGGGTGAGCGCGCCGCGCAGGGCGG
CCTCGGGACCCTCGGGCAGCGCTCCCGCAGTTGCAGCAGCAGCAGCACAGCCAGGCTCGTATCCCGCGCTGAGTGCACAGGCAGCCCGGG
AGCCGGCCGCCTTCTGGGGGCCTCTGGCGCGGGACACTCTCGTGTGGGACACCCCCTACCACACCGTCTGGGACTGCGACTTCAGCACTG
GCAAGATCGGCTGGTTCCTGGGAGGCCAGTTAAATGTCTCTGTCAACTGCTTGGACCAGCATGTTCGGAAGTCCCCCGAGAGCGTTGCTT
TGATCTGGGAGCGCGATGAGCCTGGAACGGAAGTGAGGATCACCTACAGGGAACTACTGGAGACCACGTGCCGCCTGGCCAACACGCTGA
AGAGGCATGGAGTCCACCGTGGGGACCGTGTTGCCATCTACATGCCCGTGTCCCCATTGGCTGTGGCAGCAATGCTGGCCTGTGCCAGGA
TCGGAGCTGTCCACACAGTCATCTTTGCTGGCTTCAGTGCAGAGTCCTTGGCTGGGAGGATCAATGATGCTTCTCCATATACAACCTCAA
CTCCAAACATCAACAGTGTGAGAAATGCTGATTCGAGAGGATCTCTCATAAGCACAGATTCGGGTAACAGCCTTCCAGAAAGGAATAGTG
AGAAGAGCAATTCCCTGGATAAGCACCAACAAAGTAGCACATTGGGAAATTCCGTGGTTCGCTGTGATAAACTTGACCAGTCTGAGATTA
AGAGCCTACTGATGTGTTTCCTCTACATCTTAAAGAGCATGTCTGATGATGCTTTGTTTACATATTGGAACAAGGCTTCAACATCTGAAC
TTATGGATTTTTTTACAATATCTGAAGTCTGCCTGCACCAGTTCCAGTACATGGGGAAGCGATACATAGCCAGAACAGGAATGATGCATG
CCAGATTGCAGCAGCTGGGCAGCCTGGATAACTCTCTCACTTTTAACCACAGCTATGGCCACTCGGACGCAGATGTTCTGCACCAGTCAT
TACTTGAAGCCAACATTGCTACTGAGGTTTGCCTGACAGCTCTGGACACGCTTTCTCTATTTACATTGGCGTTTAAGAACCAGCTCCTGG
CCGACCATGGACATAATCCTCTCATGAAAAAAGTTTTTGATGTCTACCTGTGTTTTCTTCAAAAACATCAGTCTGAAACGGCTTTAAAAA
ATGTCTTCACTGCCTTAAGGTCCTTAATTTATAAGTTTCCCTCAACATTCTATGAAGGGAGAGCGGACATGTGTGCGGCTCTGTGTTACG
AGATTCTCAAGTGCTGTAACTCCAAGCTGAGCTCCATCAGGACGGAGGCCTCCCAGCTGCTCTACTTCCTGATGAGGAACAACTTTGATT
ACACTGGAAAGAAGTCCTTTGTCCGGACACATTTGCAAGTCATCATATCTGTCAGCCAGCTGATAGCAGACGTTGTTGGCATTGGGGGAA
CCAGATTCCAGCAGTCCCTGTCCATCATCAACAACTGTGCCAACAGTGACCGGCTTATTAAGCACACCAGCTTCTCCTCTGATGTGAAGG
ACTTAACCAAAAGGATACGCACGGTGCTAATGGCCACCGCCCAGATGAAGGAGCATGAGAACGACCCAGAGATGCTGGTGGACCTCCAGT
ACAGCCTGGCCAAATCCTATGCCAGCACGCCCGAGCTCAGGAAGACGTGGCTCGACAGCATGGCCAGGATCCATGTCAAAAATGGCGATC
TCTCAGAGGCAGCAATGTGCTATGTCCACGTAACAGCCCTAGTGGCAGAATATCTCACACGGAAAGAAGCAGTCCAGTGGGAGCCGCCCC
TTCTCCCCCACAGCCATAGCGCCTGCCTGAGGAGGAGCCGGGGAGGCGTGTTTAGACAAGGATGCACCGCCTTCAGGGTCATTACCCCAA
ACATCGACGAGGAGGCCTCCATGATGGAAGACGTGGGGATGCAGGATGTCCATTTCAACGAGGATGTGCTGATGGAGCTCCTTGAGCAGT
GCGCAGATGGACTCTGGAAAGCCGAGCGCTACGAGCTCATCGCCGACATCTACAAACTTATCATCCCCATTTATGAGAAGCGGAGGGATT
TTGAGAGGCTGGCCCATCTGTATGACACGCTGCACCGGGCCTACAGCAAAGTGACCGAGGTCATGCACTCGGGCCGCAGGCTTCTGGGGA
CCTACTTCCGGGTAGCCTTCTTCGGGCAGGCAGCGCAATACCAGTTTACAGACAGTGAAACAGATGTGGAGGGATTCTTTGAAGATGAAG
ATGGAAAGGAGTATATTTACAAGGAACCCAAACTCACACCGCTGTCGGAAATTTCTCAGAGACTCCTTAAACTGTACTCGGATAAATTTG
GTTCTGAAAATGTCAAAATGATACAGGATTCTGGCAAGGTCAACCCTAAGGATCTGGATTCTAAGTATGCATACATCCAGGTGACTCACG
TCATCCCCTTCTTTGACGAAAAAGAGTTGCAAGAAAGGAAAACAGAGTTTGAGAGATCCCACAACATCCGCCGCTTCATGTTTGAGATGC
CATTTACGCAGACCGGGAAGAGGCAGGGCGGGGTGGAAGAGCAGTGCAAACGGCGCACCATCCTGACAGCCATACACTGCTTCCCTTATG
TGAAGAAGCGCATCCCTGTCATGTACCAGCACCACACTGACCTGAACCCCATCGAGGTGGCCATTGACGAGATGAGTAAGAAGGTGGCGG
AGCTCCGGCAGCTGTGCTCCTCGGCCGAGGTGGACATGATCAAACTGCAGCTCAAACTCCAGGGCAGCGTGAGTGTTCAGGTCAATGCTG
GCCCACTAGCATATGCGCGAGCTTTCTTAGATGATACAAACACAAAGCGATATCCTGACAATAAAGTGAAGCTGCTTAAGGAAGTTTTCA
GGCAATTTGTGGAAGCTTGCGGTCAAGCCTTAGCGGTAAACGAACGTCTGATTAAAGAAGACCAGCTCGAGTATCAGGAAGAAATGAAAG
CCAACTACAGGGAAATGGCGAAGGAGCTTTCTGAAATCATGCATGAGCAGCTGGGATGATCTGCCCCCTGGAGGAGAAGACGAGCGTCTT
ACCGAATTCCCTTCACATCTTCAACGCCATCAGTGGGACTCCAACAAGCACAATGGTTCACGGGATGACCAGCTCGTCTTCGGTCGTGTG
ATTACATCTCATGGCCCGTGTGTGGGGACTTGCTTTGTCATTTGCAAACTCAGGATGCTTTCCAAAGCCAATCACTGGGGAGACCGAGCA
CAGGGAGGACCAAGGGGAAGGGGAGAGAAAGGAAATAAAGAACAACGTTATTTCTTAACAGACTTTCTATAGGAGTTGTAAGAAGGTGCA
CATATTTTTTTAAATCTCACTGGCAATATTCAAAGTTTTCATTGTGTCTTAACAAAGGTGTGGTAGACACTCTTGAGCTGGACTTAGATT
TTATTCTTCCTTGCAGAGTAGTGTTAGAATAGATGGCCTACAGAAAAAAAAGGTTCTGGGATCTACATGGCAGGGAGGGCTGCACTGACA
TTGATGCCTGGGGGACCTTTTGCCTCGAGGCTGAGCTGGAAAATCTTGAAAATATTTTTTTTTTCCTGTGGCACATTCAGGTTGAATACA
AGAACTATTTTTGTGACTAGTTTTTGATGACCTAAGGGAACTGACCATTGTAATTTTTGTACCAGTGAACCAGGAGATTTAGTGCTTTTA
TATTCATTTCCTTGCATTTAAGAAAATATGAAAGCTTAAGGAATTATGTGAGCTTAAAACTAGTCAAGCAGTTTAGAACCAAAGGCCTAT
ATTAATAACCGCAACTATGCTGAAAAGTACAAAGTAGTACAGTATATTGTTATGTACATATCATTGTTAATACAGTCCTGGCATTCTGTA
CATATATGTATTACATTTCTACATTTTTAATACTCACATGGGCTTATGCATTAAGTTTAATTGTGATAAATTTGTGCTGTTCCAGTATAT
GCAATACACTTTAATGTTTTATTCTTGTACATAAAAATGTGCAATATGGAGATGTATACAGTCTTTACTATATTAGGTTTATAAACAGTT
TTAAGAATTTCATCCTTTTGCCAAAATGGTGGAGTATGTAATTGGTAAATCATAAATCCTGTGGTGAATGGTGGTGTACTTTAAAGCTGT
CACCATGTTATATTTTCTTTTAAGACTTTAATTTAGTAATTTTATATTTGGGAAAATAAAGGTTTTTAATTTTATTTAACTGGAATCACT
GCCCTGCTGTAATTAAACATTCTGTACCACATCTGTATTAAAAAGACATTGCTGACCATT

>1535_1535_5_ACSS1-DOCK9_ACSS1_chr20_25011394_ENST00000432802_DOCK9_chr13_99508285_ENST00000376460_length(amino acids)=1046AA_BP=210
MAARTLGRGVGRLLGSLRGLSGQPARPPCGVSAPRRAASGPSGSAPAVAAAAAQPGSYPALSAQAAREPAAFWGPLARDTLVWDTPYHTV
WDCDFSTGKIGWFLGGQLNVSVNCLDQHVRKSPESVALIWERDEPGTEVRITYRELLETTCRLANTLKRHGVHRGDRVAIYMPVSPLAVA
AMLACARIGAVHTVIFAGFSAESLAGRINDASPYTTSTPNINSVRNADSRGSLISTDSGNSLPERNSEKSNSLDKHQQSSTLGNSVVRCD
KLDQSEIKSLLMCFLYILKSMSDDALFTYWNKASTSELMDFFTISEVCLHQFQYMGKRYIARTGMMHARLQQLGSLDNSLTFNHSYGHSD
ADVLHQSLLEANIATEVCLTALDTLSLFTLAFKNQLLADHGHNPLMKKVFDVYLCFLQKHQSETALKNVFTALRSLIYKFPSTFYEGRAD
MCAALCYEILKCCNSKLSSIRTEASQLLYFLMRNNFDYTGKKSFVRTHLQVIISVSQLIADVVGIGGTRFQQSLSIINNCANSDRLIKHT
SFSSDVKDLTKRIRTVLMATAQMKEHENDPEMLVDLQYSLAKSYASTPELRKTWLDSMARIHVKNGDLSEAAMCYVHVTALVAEYLTRKE
AVQWEPPLLPHSHSACLRRSRGGVFRQGCTAFRVITPNIDEEASMMEDVGMQDVHFNEDVLMELLEQCADGLWKAERYELIADIYKLIIP
IYEKRRDFERLAHLYDTLHRAYSKVTEVMHSGRRLLGTYFRVAFFGQAAQYQFTDSETDVEGFFEDEDGKEYIYKEPKLTPLSEISQRLL
KLYSDKFGSENVKMIQDSGKVNPKDLDSKYAYIQVTHVIPFFDEKELQERKTEFERSHNIRRFMFEMPFTQTGKRQGGVEEQCKRRTILT
AIHCFPYVKKRIPVMYQHHTDLNPIEVAIDEMSKKVAELRQLCSSAEVDMIKLQLKLQGSVSVQVNAGPLAYARAFLDDTNTKRYPDNKV
KLLKEVFRQFVEACGQALAVNERLIKEDQLEYQEEMKANYREMAKELSEIMHEQLG

--------------------------------------------------------------
>1535_1535_6_ACSS1-DOCK9_ACSS1_chr20_25011394_ENST00000432802_DOCK9_chr13_99508285_ENST00000448493_length(transcript)=3257nt_BP=1509nt
AAAAGGAAAACGAGGCACCGAGAAGTTAAGGAACTTGCTCAAGGTCACAGAGTTTGAACTCAGGCTACAGATGCTGCAGCAACTGGAGAA
AGTCCTCATCGCCCCATATCACCCACCACCGACCCCCAGCAGGACGTGACCCCCGCCAGGACGGAGGCCGGCAGCTGGGGGGCTGGAGCA
TGGGACCCAGAACACGGACTCAGGCTTGCGCAGCCTCCTGGCTTCTAGGCGGGAGCCTAGAAAGGCGCCAGCCCCTTTCGCGTGCTGCTG
AGACTCCAGGGGTGGGGTTCACTCTCAGGGGCGCACAAAGGCATGAAAACCTTGGCTTCAGCCTCTGAGATGCGGAACTGACCGACCTAT
TGTCTTGGGACCCACCAGTGCGCTTGGGTGCACCAGCCCCCTTAACGTTGGTGCCGGCTCCCTCCCGGCTCCTCCCCATCCCAGAGGGTC
CCCTCGCCCCAGGCCCTGAGCCTGCGTCCTGGGGTCCTGGGCCGCACGTGCCTCTGGCAGCTCGAAGAAGCTGTCGGGGCTTGCAGGAGA
GCGTGCAAACTGAAACCAAAACAGGCCGACTCGAGGAACATCCGGGTGGGACCGCAGACTCACCGGAGCGCAGCGCCTGGGCCAGGGCCT
GGGACCCTGCTCCGCCCCGCGCTCCCCTGCACCCCTTCCCCACGCTGCTCCCCTCTTCCTAAGCGGCCCCCCCTCTCCCGGGCAGCAGAA
GAAGGGGTGGGACCCGGGCGGGCTCCGGGAGGGGGCCCTGGAGGAATGGATGGTGGCGGAAGGGCGGAGCAGGGGCGGGGCCCGCGGAGA
CTCCACGGGGCGCCCCGGGCGTGAGGCACCCACTCTGGGAGCACAGAGAGCTCAGGTAGCCTGCCTAGATGGCGGCGCGCACCCTGGGCC
GCGGCGTCGGGAGGCTGCTGGGCAGCCTGCGAGGGCTCTCGGGGCAGCCCGCGCGGCCGCCGTGCGGGGTGAGCGCGCCGCGCAGGGCGG
CCTCGGGACCCTCGGGCAGCGCTCCCGCAGTTGCAGCAGCAGCAGCACAGCCAGGCTCGTATCCCGCGCTGAGTGCACAGGCAGCCCGGG
AGCCGGCCGCCTTCTGGGGGCCTCTGGCGCGGGACACTCTCGTGTGGGACACCCCCTACCACACCGTCTGGGACTGCGACTTCAGCACTG
GCAAGATCGGCTGGTTCCTGGGAGGCCAGTTAAATGTCTCTGTCAACTGCTTGGACCAGCATGTTCGGAAGTCCCCCGAGAGCGTTGCTT
TGATCTGGGAGCGCGATGAGCCTGGAACGGAAGTGAGGATCACCTACAGGGAACTACTGGAGACCACGTGCCGCCTGGCCAACACGCTGA
AGAGGCATGGAGTCCACCGTGGGGACCGTGTTGCCATCTACATGCCCGTGTCCCCATTGGCTGTGGCAGCAATGCTGGCCTGTGCCAGGA
TCGGAGCTGTCCACACAGTCATCTTTGCTGGCTTCAGTGCAGAGTCCTTGGCTGGGAGGATCAATGATGCTTCTCCATATACAACCTCAA
CTCCAAACATCAACAGTGTGAGAAATGCTGATTCGAGAGGATCTCTCATAAGCACAGATTCGGGTAACAGCCTTCCAGAAAGGAATAGTG
AGAAGAGCAATTCCCTGGATAAGCACCAACAAAGTAGCACATTGGGAAATTCCGTGGTTCGCTGTGATAAACTTGACCAGTCTGAGATTA
AGAGCCTACTGATGTGTTTCCTCTACATCTTAAAGAGCATGTCTGATGATGCTTTGTTTACATATTGGAACAAGGCTTCAACATCTGAAC
TTATGGATTTTTTTACAATATCTGAAGTCTGCCTGCACCAGTTCCAGTACATGGGGAAGCGATACATAGCCAGTTTAACAAAGTGTGTGG
CTCTTCTCCTTCCTGCTTGGAACAGGAATGATGCATGCCAGATTGCAGCAGCTGGGCAGCCTGGATAACTCTCTCACTTTTAACCACAGC
TATGGCCACTCGGACGCAGATGTTCTGCACCAGTCATTACTTGAAGCCAACATTGCTACTGAGGTTTGCCTGACAGCTCTGGACACGCTT
TCTCTATTTACATTGGCGTTTAAGAACCAGCTCCTGGCCGACCATGGACATAATCCTCTCATGAAAAAAGTTTTTGATGTCTACCTGTGT
TTTCTTCAAAAACATCAGTCTGAAACGGCTTTAAAAAATGTCTTCACTGCCTTAAGGTCCTTAATTTATAAGTTTCCCTCAACATTCTAT
GAAGGGAGAGCGGACATGTGTGCGGCTCTGTGTTACGAGATTCTCAAGTGCTGTAACTCCAAGCTGAGCTCCATCAGGACGGAGGCCTCC
CAGCTGCTCTACTTCCTGATGAGGAACAACTTTGATTACACTGGAAAGAAGTCCTTTGTCCGGACACATTTGCAAGTCATCATATCTGTC
AGCCAGCTGATAGCAGACGTTGTTGGCATTGGGGGAACCAGATTCCAGCAGTCCCTGTCCATCATCAACAACTGTGCCAACAGTGACCGG
CTTATTAAGCACACCAGCTTCTCCTCTGATGTGAAGGACTTAACCAAAAGGATACGCACGGTGCTAATGGCCACCGCCCAGATGAAGGAG
CATGAGAACGACCCAGAGATGCTGGTGGACCTCCAGTACAGCCTGGCCAAATCCTATGCCAGCACGCCCGAGCTCAGGAAGACGTGGCTC
GACAGCATGGCCAGGATCCATGTCAAAAATGGCGATCTCTCAGAGGCAGCAATGTGCTATGTCCACGTAACAGCCCTAGTGGCAGAATAT
CTCACACGGAAAGAAGCAGTCCAGTGGGAGCCGCCCCTTCTCCCCCACAGCCATAGCGCCTGCCTGAGGAGGAGCCGGGGAGGCGTGTTT
AGACAAGGATGCACCGCCTTCAGGGTCATTACCCCAAACATCGACGAGGAGGCCTCCATGATGGAAGACGTGGGGATGCAGGATGTCCAT
TTCAACGAGGATGTGCTGATGGAGCTCCTTGAGCAGTGCGCAGATGGACTCTGGAAAGCCGAGCGCTACGAGCTCATCGCCGACATCTAC
AAACTTATCATCCCCATTTATGAGAAGCGGAGGGATTTTGAGAGGCTGGCCCATCTGTATGACACGCTGCACCGGGCCTACAGCAAAGTG
ACCGAGGTCATGCACTCGGGCCGCAGGCTTCTGGGGACCTACTTCCGGGTAGCCTTCTTCGGGCAGGTGAGCCTCCTGTCCATTCTGCAG
ACTGTCCTAAGTCCTTT

>1535_1535_6_ACSS1-DOCK9_ACSS1_chr20_25011394_ENST00000432802_DOCK9_chr13_99508285_ENST00000448493_length(amino acids)=451AA_BP=
MLGTGMMHARLQQLGSLDNSLTFNHSYGHSDADVLHQSLLEANIATEVCLTALDTLSLFTLAFKNQLLADHGHNPLMKKVFDVYLCFLQK
HQSETALKNVFTALRSLIYKFPSTFYEGRADMCAALCYEILKCCNSKLSSIRTEASQLLYFLMRNNFDYTGKKSFVRTHLQVIISVSQLI
ADVVGIGGTRFQQSLSIINNCANSDRLIKHTSFSSDVKDLTKRIRTVLMATAQMKEHENDPEMLVDLQYSLAKSYASTPELRKTWLDSMA
RIHVKNGDLSEAAMCYVHVTALVAEYLTRKEAVQWEPPLLPHSHSACLRRSRGGVFRQGCTAFRVITPNIDEEASMMEDVGMQDVHFNED
VLMELLEQCADGLWKAERYELIADIYKLIIPIYEKRRDFERLAHLYDTLHRAYSKVTEVMHSGRRLLGTYFRVAFFGQVSLLSILQTVLS
P

--------------------------------------------------------------
>1535_1535_7_ACSS1-DOCK9_ACSS1_chr20_25011394_ENST00000542618_DOCK9_chr13_99508285_ENST00000339416_length(transcript)=3117nt_BP=535nt
CCTTTCCTTGACTACCCTTTGAACAGAGGAGAGCTATGCAAACACGCTGCGAGCGGCCTTGAGAGCCCGAGGAGGGTCTGCTTTCTGGGC
CCCTGCAGAGGGCAGGGGTCGCGGGCTGGTGGTCTGCCCCGCCCAGAGAGAAAGGGCCTTGGCTTCCCCTCATTCTTCGTTCTGTGTTAG
CTCTTTTTATTGCAAATAATTAATTAAAGTCAGTACAGCAAGAGTGGGAAAGTGGTTAATGCAATTGCCAGGTCCAGATTCAGAGGGATG
AGGCGCCGAAAGGAAAGACAACCTTGGGATCGCTTCCACTTCCTCCACTTCGCACCGCATGGCCGGGAACTACTGGAGACCACGTGCCGC
CTGGCCAACACGCTGAAGAGGCATGGAGTCCACCGTGGGGACCGTGTTGCCATCTACATGCCCGTGTCCCCATTGGCTGTGGCAGCAATG
CTGGCCTGTGCCAGGATCGGAGCTGTCCACACAGTCATCTTTGCTGGCTTCAGTGCAGAGTCCTTGGCTGGGAGGATCAATGATGCTTCT
CCATATACAACCTCAACTCCAAACATCAACAGTGTGAGAAATGCTGATTCGAGAGGATCTCTCATAAGCACAGATTCGGGTAACAGCCTT
CCAGAAAGGAATAGTGAGAAGAGCAATTCCCTGGATAAGCACCAACAAAGTAGCACATTGGGAAATTCCGTGGTTCGCTGTGATAAACTT
GACCAGTCTGAGATTAAGAGCCTACTGATGTGTTTCCTCTACATCTTAAAGAGCATGTCTGATGATGCTTTGTTTACATATTGGAACAAG
GCTTCAACATCTGAACTTATGGATTTTTTTACAATATCTGAAGTCTGCCTGCACCAGTTCCAGTACATGGGGAAGCGATACATAGCCAGA
ACAGGAATGATGCATGCCAGATTGCAGCAGCTGGGCAGCCTGGATAACTCTCTCACTTTTAACCACAGCTATGGCCACTCGGACGCAGAT
GTTCTGCACCAGTCATTACTTGAAGCCAACATTGCTACTGAGGTTTGCCTGACAGCTCTGGACACGCTTTCTCTATTTACATTGGCGTTT
AAGAACCAGCTCCTGGCCGACCATGGACATAATCCTCTCATGAAAAAAGTTTTTGATGTCTACCTGTGTTTTCTTCAAAAACATCAGTCT
GAAACGGCTTTAAAAAATGTCTTCACTGCCTTAAGGTCCTTAATTTATAAGTTTCCCTCAACATTCTATGAAGGGAGAGCGGACATGTGT
GCGGCTCTGTGTTACGAGATTCTCAAGTGCTGTAACTCCAAGCTGAGCTCCATCAGGACGGAGGCCTCCCAGCTGCTCTACTTCCTGATG
AGGAACAACTTTGATTACACTGGAAAGAAGTCCTTTGTCCGGACACATTTGCAAGTCATCATATCTGTCAGCCAGCTGATAGCAGACGTT
GTTGGCATTGGGGGAACCAGATTCCAGCAGTCCCTGTCCATCATCAACAACTGTGCCAACAGTGACCGGCTTATTAAGCACACCAGCTTC
TCCTCTGATGTGAAGGACTTAACCAAAAGGATACGCACGGTGCTAATGGCCACCGCCCAGATGAAGGAGCATGAGAACGACCCAGAGATG
CTGGTGGACCTCCAGTACAGCCTGGCCAAATCCTATGCCAGCACGCCCGAGCTCAGGAAGACGTGGCTCGACAGCATGGCCAGGATCCAT
GTCAAAAATGGCGATCTCTCAGAGGCAGCAATGTGCTATGTCCACGTAACAGCCCTAGTGGCAGAATATCTCACACGGAAAGAAGCAGTC
CAGTGGGAGCCGCCCCTTCTCCCCCACAGCCATAGCGCCTGCCTGAGGAGGAGCCGGGGAGGCGTGTTTAGACAAGGATGCACCGCCTTC
AGGGTCATTACCCCAAACATCGACGAGGAGGCCTCCATGATGGAAGACGTGGGGATGCAGGATGTCCATTTCAACGAGGATGTGCTGATG
GAGCTCCTTGAGCAGTGCGCAGATGGACTCTGGAAAGCCGAGCGCTACGAGCTCATCGCCGACATCTACAAACTTATCATCCCCATTTAT
GAGAAGCGGAGGGATTTTGAGAGGCTGGCCCATCTGTATGACACGCTGCACCGGGCCTACAGCAAAGTGACCGAGGTCATGCACTCGGGC
CGCAGGCTTCTGGGGACCTACTTCCGGGTAGCCTTCTTCGGGCAGGGATTCTTTGAAGATGAAGATGGAAAGGAGTATATTTACAAGGAA
CCCAAACTCACACCGCTGTCGGAAATTTCTCAGAGACTCCTTAAACTGTACTCGGATAAATTTGGTTCTGAAAATGTCAAAATGATACAG
GATTCTGGCAAGGTCAACCCTAAGGATCTGGATTCTAAGTATGCATACATCCAGGTGACTCACGTCATCCCCTTCTTTGACGAAAAAGAG
TTGCAAGAAAGGAAAACAGAGTTTGAGAGATCCCACAACATCCGCCGCTTCATGTTTGAGATGCCATTTACGCAGACCGGGAAGAGGCAG
GGCGGGGTGGAAGAGCAGTGCAAACGGCGCACCATCCTGACAGCCATACACTGCTTCCCTTATGTGAAGAAGCGCATCCCTGTCATGTAC
CAGCACCACACTGACCTGAACCCCATCGAGGTGGCCATTGACGAGATGAGTAAGAAGGTGGCGGAGCTCCGGCAGCTGTGCTCCTCGGCC
GAGGTGGACATGATCAAACTGCAGCTCAAACTCCAGGGCAGCGTGAGTGTTCAGGTCAATGCTGGCCCACTAGCATATGCGCGAGCTTTC
TTAGATGATACAAACACAAAGCGATATCCTGACAATAAAGTGAAGCTGCTTAAGGAAGTTTTCAGGCAATTTGTGGAAGCTTGCGGTCAA
GCCTTAGCGGTAAACGAACGTCTGATTAAAGAAGACCAGCTCGAGTATCAGGAAGAAATGAAAGCCAACTACAGGGAAATGGCGAAGGAG
CTTTCTGAAATCATGCATGAGCAGATCTGCCCCCTGGAGGAGAAGACGAGCGTCTTACCGAATTCCCTTCACATCTTCAACGCCATCAGT
GGGACTCCAACAAGCACAATGGTTCACGGGATGACCAGCTCGTCTTCGGTCGTGTGA

>1535_1535_7_ACSS1-DOCK9_ACSS1_chr20_25011394_ENST00000542618_DOCK9_chr13_99508285_ENST00000339416_length(amino acids)=949AA_BP=89
MRRRKERQPWDRFHFLHFAPHGRELLETTCRLANTLKRHGVHRGDRVAIYMPVSPLAVAAMLACARIGAVHTVIFAGFSAESLAGRINDA
SPYTTSTPNINSVRNADSRGSLISTDSGNSLPERNSEKSNSLDKHQQSSTLGNSVVRCDKLDQSEIKSLLMCFLYILKSMSDDALFTYWN
KASTSELMDFFTISEVCLHQFQYMGKRYIARTGMMHARLQQLGSLDNSLTFNHSYGHSDADVLHQSLLEANIATEVCLTALDTLSLFTLA
FKNQLLADHGHNPLMKKVFDVYLCFLQKHQSETALKNVFTALRSLIYKFPSTFYEGRADMCAALCYEILKCCNSKLSSIRTEASQLLYFL
MRNNFDYTGKKSFVRTHLQVIISVSQLIADVVGIGGTRFQQSLSIINNCANSDRLIKHTSFSSDVKDLTKRIRTVLMATAQMKEHENDPE
MLVDLQYSLAKSYASTPELRKTWLDSMARIHVKNGDLSEAAMCYVHVTALVAEYLTRKEAVQWEPPLLPHSHSACLRRSRGGVFRQGCTA
FRVITPNIDEEASMMEDVGMQDVHFNEDVLMELLEQCADGLWKAERYELIADIYKLIIPIYEKRRDFERLAHLYDTLHRAYSKVTEVMHS
GRRLLGTYFRVAFFGQGFFEDEDGKEYIYKEPKLTPLSEISQRLLKLYSDKFGSENVKMIQDSGKVNPKDLDSKYAYIQVTHVIPFFDEK
ELQERKTEFERSHNIRRFMFEMPFTQTGKRQGGVEEQCKRRTILTAIHCFPYVKKRIPVMYQHHTDLNPIEVAIDEMSKKVAELRQLCSS
AEVDMIKLQLKLQGSVSVQVNAGPLAYARAFLDDTNTKRYPDNKVKLLKEVFRQFVEACGQALAVNERLIKEDQLEYQEEMKANYREMAK
ELSEIMHEQICPLEEKTSVLPNSLHIFNAISGTPTSTMVHGMTSSSSVV

--------------------------------------------------------------
>1535_1535_8_ACSS1-DOCK9_ACSS1_chr20_25011394_ENST00000542618_DOCK9_chr13_99508285_ENST00000376460_length(transcript)=4306nt_BP=535nt
CCTTTCCTTGACTACCCTTTGAACAGAGGAGAGCTATGCAAACACGCTGCGAGCGGCCTTGAGAGCCCGAGGAGGGTCTGCTTTCTGGGC
CCCTGCAGAGGGCAGGGGTCGCGGGCTGGTGGTCTGCCCCGCCCAGAGAGAAAGGGCCTTGGCTTCCCCTCATTCTTCGTTCTGTGTTAG
CTCTTTTTATTGCAAATAATTAATTAAAGTCAGTACAGCAAGAGTGGGAAAGTGGTTAATGCAATTGCCAGGTCCAGATTCAGAGGGATG
AGGCGCCGAAAGGAAAGACAACCTTGGGATCGCTTCCACTTCCTCCACTTCGCACCGCATGGCCGGGAACTACTGGAGACCACGTGCCGC
CTGGCCAACACGCTGAAGAGGCATGGAGTCCACCGTGGGGACCGTGTTGCCATCTACATGCCCGTGTCCCCATTGGCTGTGGCAGCAATG
CTGGCCTGTGCCAGGATCGGAGCTGTCCACACAGTCATCTTTGCTGGCTTCAGTGCAGAGTCCTTGGCTGGGAGGATCAATGATGCTTCT
CCATATACAACCTCAACTCCAAACATCAACAGTGTGAGAAATGCTGATTCGAGAGGATCTCTCATAAGCACAGATTCGGGTAACAGCCTT
CCAGAAAGGAATAGTGAGAAGAGCAATTCCCTGGATAAGCACCAACAAAGTAGCACATTGGGAAATTCCGTGGTTCGCTGTGATAAACTT
GACCAGTCTGAGATTAAGAGCCTACTGATGTGTTTCCTCTACATCTTAAAGAGCATGTCTGATGATGCTTTGTTTACATATTGGAACAAG
GCTTCAACATCTGAACTTATGGATTTTTTTACAATATCTGAAGTCTGCCTGCACCAGTTCCAGTACATGGGGAAGCGATACATAGCCAGA
ACAGGAATGATGCATGCCAGATTGCAGCAGCTGGGCAGCCTGGATAACTCTCTCACTTTTAACCACAGCTATGGCCACTCGGACGCAGAT
GTTCTGCACCAGTCATTACTTGAAGCCAACATTGCTACTGAGGTTTGCCTGACAGCTCTGGACACGCTTTCTCTATTTACATTGGCGTTT
AAGAACCAGCTCCTGGCCGACCATGGACATAATCCTCTCATGAAAAAAGTTTTTGATGTCTACCTGTGTTTTCTTCAAAAACATCAGTCT
GAAACGGCTTTAAAAAATGTCTTCACTGCCTTAAGGTCCTTAATTTATAAGTTTCCCTCAACATTCTATGAAGGGAGAGCGGACATGTGT
GCGGCTCTGTGTTACGAGATTCTCAAGTGCTGTAACTCCAAGCTGAGCTCCATCAGGACGGAGGCCTCCCAGCTGCTCTACTTCCTGATG
AGGAACAACTTTGATTACACTGGAAAGAAGTCCTTTGTCCGGACACATTTGCAAGTCATCATATCTGTCAGCCAGCTGATAGCAGACGTT
GTTGGCATTGGGGGAACCAGATTCCAGCAGTCCCTGTCCATCATCAACAACTGTGCCAACAGTGACCGGCTTATTAAGCACACCAGCTTC
TCCTCTGATGTGAAGGACTTAACCAAAAGGATACGCACGGTGCTAATGGCCACCGCCCAGATGAAGGAGCATGAGAACGACCCAGAGATG
CTGGTGGACCTCCAGTACAGCCTGGCCAAATCCTATGCCAGCACGCCCGAGCTCAGGAAGACGTGGCTCGACAGCATGGCCAGGATCCAT
GTCAAAAATGGCGATCTCTCAGAGGCAGCAATGTGCTATGTCCACGTAACAGCCCTAGTGGCAGAATATCTCACACGGAAAGAAGCAGTC
CAGTGGGAGCCGCCCCTTCTCCCCCACAGCCATAGCGCCTGCCTGAGGAGGAGCCGGGGAGGCGTGTTTAGACAAGGATGCACCGCCTTC
AGGGTCATTACCCCAAACATCGACGAGGAGGCCTCCATGATGGAAGACGTGGGGATGCAGGATGTCCATTTCAACGAGGATGTGCTGATG
GAGCTCCTTGAGCAGTGCGCAGATGGACTCTGGAAAGCCGAGCGCTACGAGCTCATCGCCGACATCTACAAACTTATCATCCCCATTTAT
GAGAAGCGGAGGGATTTTGAGAGGCTGGCCCATCTGTATGACACGCTGCACCGGGCCTACAGCAAAGTGACCGAGGTCATGCACTCGGGC
CGCAGGCTTCTGGGGACCTACTTCCGGGTAGCCTTCTTCGGGCAGGCAGCGCAATACCAGTTTACAGACAGTGAAACAGATGTGGAGGGA
TTCTTTGAAGATGAAGATGGAAAGGAGTATATTTACAAGGAACCCAAACTCACACCGCTGTCGGAAATTTCTCAGAGACTCCTTAAACTG
TACTCGGATAAATTTGGTTCTGAAAATGTCAAAATGATACAGGATTCTGGCAAGGTCAACCCTAAGGATCTGGATTCTAAGTATGCATAC
ATCCAGGTGACTCACGTCATCCCCTTCTTTGACGAAAAAGAGTTGCAAGAAAGGAAAACAGAGTTTGAGAGATCCCACAACATCCGCCGC
TTCATGTTTGAGATGCCATTTACGCAGACCGGGAAGAGGCAGGGCGGGGTGGAAGAGCAGTGCAAACGGCGCACCATCCTGACAGCCATA
CACTGCTTCCCTTATGTGAAGAAGCGCATCCCTGTCATGTACCAGCACCACACTGACCTGAACCCCATCGAGGTGGCCATTGACGAGATG
AGTAAGAAGGTGGCGGAGCTCCGGCAGCTGTGCTCCTCGGCCGAGGTGGACATGATCAAACTGCAGCTCAAACTCCAGGGCAGCGTGAGT
GTTCAGGTCAATGCTGGCCCACTAGCATATGCGCGAGCTTTCTTAGATGATACAAACACAAAGCGATATCCTGACAATAAAGTGAAGCTG
CTTAAGGAAGTTTTCAGGCAATTTGTGGAAGCTTGCGGTCAAGCCTTAGCGGTAAACGAACGTCTGATTAAAGAAGACCAGCTCGAGTAT
CAGGAAGAAATGAAAGCCAACTACAGGGAAATGGCGAAGGAGCTTTCTGAAATCATGCATGAGCAGCTGGGATGATCTGCCCCCTGGAGG
AGAAGACGAGCGTCTTACCGAATTCCCTTCACATCTTCAACGCCATCAGTGGGACTCCAACAAGCACAATGGTTCACGGGATGACCAGCT
CGTCTTCGGTCGTGTGATTACATCTCATGGCCCGTGTGTGGGGACTTGCTTTGTCATTTGCAAACTCAGGATGCTTTCCAAAGCCAATCA
CTGGGGAGACCGAGCACAGGGAGGACCAAGGGGAAGGGGAGAGAAAGGAAATAAAGAACAACGTTATTTCTTAACAGACTTTCTATAGGA
GTTGTAAGAAGGTGCACATATTTTTTTAAATCTCACTGGCAATATTCAAAGTTTTCATTGTGTCTTAACAAAGGTGTGGTAGACACTCTT
GAGCTGGACTTAGATTTTATTCTTCCTTGCAGAGTAGTGTTAGAATAGATGGCCTACAGAAAAAAAAGGTTCTGGGATCTACATGGCAGG
GAGGGCTGCACTGACATTGATGCCTGGGGGACCTTTTGCCTCGAGGCTGAGCTGGAAAATCTTGAAAATATTTTTTTTTTCCTGTGGCAC
ATTCAGGTTGAATACAAGAACTATTTTTGTGACTAGTTTTTGATGACCTAAGGGAACTGACCATTGTAATTTTTGTACCAGTGAACCAGG
AGATTTAGTGCTTTTATATTCATTTCCTTGCATTTAAGAAAATATGAAAGCTTAAGGAATTATGTGAGCTTAAAACTAGTCAAGCAGTTT
AGAACCAAAGGCCTATATTAATAACCGCAACTATGCTGAAAAGTACAAAGTAGTACAGTATATTGTTATGTACATATCATTGTTAATACA
GTCCTGGCATTCTGTACATATATGTATTACATTTCTACATTTTTAATACTCACATGGGCTTATGCATTAAGTTTAATTGTGATAAATTTG
TGCTGTTCCAGTATATGCAATACACTTTAATGTTTTATTCTTGTACATAAAAATGTGCAATATGGAGATGTATACAGTCTTTACTATATT
AGGTTTATAAACAGTTTTAAGAATTTCATCCTTTTGCCAAAATGGTGGAGTATGTAATTGGTAAATCATAAATCCTGTGGTGAATGGTGG
TGTACTTTAAAGCTGTCACCATGTTATATTTTCTTTTAAGACTTTAATTTAGTAATTTTATATTTGGGAAAATAAAGGTTTTTAATTTTA
TTTAACTGGAATCACTGCCCTGCTGTAATTAAACATTCTGTACCACATCTGTATTAAAAAGACATTGCTGACCATT

>1535_1535_8_ACSS1-DOCK9_ACSS1_chr20_25011394_ENST00000542618_DOCK9_chr13_99508285_ENST00000376460_length(amino acids)=925AA_BP=89
MRRRKERQPWDRFHFLHFAPHGRELLETTCRLANTLKRHGVHRGDRVAIYMPVSPLAVAAMLACARIGAVHTVIFAGFSAESLAGRINDA
SPYTTSTPNINSVRNADSRGSLISTDSGNSLPERNSEKSNSLDKHQQSSTLGNSVVRCDKLDQSEIKSLLMCFLYILKSMSDDALFTYWN
KASTSELMDFFTISEVCLHQFQYMGKRYIARTGMMHARLQQLGSLDNSLTFNHSYGHSDADVLHQSLLEANIATEVCLTALDTLSLFTLA
FKNQLLADHGHNPLMKKVFDVYLCFLQKHQSETALKNVFTALRSLIYKFPSTFYEGRADMCAALCYEILKCCNSKLSSIRTEASQLLYFL
MRNNFDYTGKKSFVRTHLQVIISVSQLIADVVGIGGTRFQQSLSIINNCANSDRLIKHTSFSSDVKDLTKRIRTVLMATAQMKEHENDPE
MLVDLQYSLAKSYASTPELRKTWLDSMARIHVKNGDLSEAAMCYVHVTALVAEYLTRKEAVQWEPPLLPHSHSACLRRSRGGVFRQGCTA
FRVITPNIDEEASMMEDVGMQDVHFNEDVLMELLEQCADGLWKAERYELIADIYKLIIPIYEKRRDFERLAHLYDTLHRAYSKVTEVMHS
GRRLLGTYFRVAFFGQAAQYQFTDSETDVEGFFEDEDGKEYIYKEPKLTPLSEISQRLLKLYSDKFGSENVKMIQDSGKVNPKDLDSKYA
YIQVTHVIPFFDEKELQERKTEFERSHNIRRFMFEMPFTQTGKRQGGVEEQCKRRTILTAIHCFPYVKKRIPVMYQHHTDLNPIEVAIDE
MSKKVAELRQLCSSAEVDMIKLQLKLQGSVSVQVNAGPLAYARAFLDDTNTKRYPDNKVKLLKEVFRQFVEACGQALAVNERLIKEDQLE
YQEEMKANYREMAKELSEIMHEQLG

--------------------------------------------------------------
>1535_1535_9_ACSS1-DOCK9_ACSS1_chr20_25011394_ENST00000542618_DOCK9_chr13_99508285_ENST00000448493_length(transcript)=2283nt_BP=535nt
CCTTTCCTTGACTACCCTTTGAACAGAGGAGAGCTATGCAAACACGCTGCGAGCGGCCTTGAGAGCCCGAGGAGGGTCTGCTTTCTGGGC
CCCTGCAGAGGGCAGGGGTCGCGGGCTGGTGGTCTGCCCCGCCCAGAGAGAAAGGGCCTTGGCTTCCCCTCATTCTTCGTTCTGTGTTAG
CTCTTTTTATTGCAAATAATTAATTAAAGTCAGTACAGCAAGAGTGGGAAAGTGGTTAATGCAATTGCCAGGTCCAGATTCAGAGGGATG
AGGCGCCGAAAGGAAAGACAACCTTGGGATCGCTTCCACTTCCTCCACTTCGCACCGCATGGCCGGGAACTACTGGAGACCACGTGCCGC
CTGGCCAACACGCTGAAGAGGCATGGAGTCCACCGTGGGGACCGTGTTGCCATCTACATGCCCGTGTCCCCATTGGCTGTGGCAGCAATG
CTGGCCTGTGCCAGGATCGGAGCTGTCCACACAGTCATCTTTGCTGGCTTCAGTGCAGAGTCCTTGGCTGGGAGGATCAATGATGCTTCT
CCATATACAACCTCAACTCCAAACATCAACAGTGTGAGAAATGCTGATTCGAGAGGATCTCTCATAAGCACAGATTCGGGTAACAGCCTT
CCAGAAAGGAATAGTGAGAAGAGCAATTCCCTGGATAAGCACCAACAAAGTAGCACATTGGGAAATTCCGTGGTTCGCTGTGATAAACTT
GACCAGTCTGAGATTAAGAGCCTACTGATGTGTTTCCTCTACATCTTAAAGAGCATGTCTGATGATGCTTTGTTTACATATTGGAACAAG
GCTTCAACATCTGAACTTATGGATTTTTTTACAATATCTGAAGTCTGCCTGCACCAGTTCCAGTACATGGGGAAGCGATACATAGCCAGT
TTAACAAAGTGTGTGGCTCTTCTCCTTCCTGCTTGGAACAGGAATGATGCATGCCAGATTGCAGCAGCTGGGCAGCCTGGATAACTCTCT
CACTTTTAACCACAGCTATGGCCACTCGGACGCAGATGTTCTGCACCAGTCATTACTTGAAGCCAACATTGCTACTGAGGTTTGCCTGAC
AGCTCTGGACACGCTTTCTCTATTTACATTGGCGTTTAAGAACCAGCTCCTGGCCGACCATGGACATAATCCTCTCATGAAAAAAGTTTT
TGATGTCTACCTGTGTTTTCTTCAAAAACATCAGTCTGAAACGGCTTTAAAAAATGTCTTCACTGCCTTAAGGTCCTTAATTTATAAGTT
TCCCTCAACATTCTATGAAGGGAGAGCGGACATGTGTGCGGCTCTGTGTTACGAGATTCTCAAGTGCTGTAACTCCAAGCTGAGCTCCAT
CAGGACGGAGGCCTCCCAGCTGCTCTACTTCCTGATGAGGAACAACTTTGATTACACTGGAAAGAAGTCCTTTGTCCGGACACATTTGCA
AGTCATCATATCTGTCAGCCAGCTGATAGCAGACGTTGTTGGCATTGGGGGAACCAGATTCCAGCAGTCCCTGTCCATCATCAACAACTG
TGCCAACAGTGACCGGCTTATTAAGCACACCAGCTTCTCCTCTGATGTGAAGGACTTAACCAAAAGGATACGCACGGTGCTAATGGCCAC
CGCCCAGATGAAGGAGCATGAGAACGACCCAGAGATGCTGGTGGACCTCCAGTACAGCCTGGCCAAATCCTATGCCAGCACGCCCGAGCT
CAGGAAGACGTGGCTCGACAGCATGGCCAGGATCCATGTCAAAAATGGCGATCTCTCAGAGGCAGCAATGTGCTATGTCCACGTAACAGC
CCTAGTGGCAGAATATCTCACACGGAAAGAAGCAGTCCAGTGGGAGCCGCCCCTTCTCCCCCACAGCCATAGCGCCTGCCTGAGGAGGAG
CCGGGGAGGCGTGTTTAGACAAGGATGCACCGCCTTCAGGGTCATTACCCCAAACATCGACGAGGAGGCCTCCATGATGGAAGACGTGGG
GATGCAGGATGTCCATTTCAACGAGGATGTGCTGATGGAGCTCCTTGAGCAGTGCGCAGATGGACTCTGGAAAGCCGAGCGCTACGAGCT
CATCGCCGACATCTACAAACTTATCATCCCCATTTATGAGAAGCGGAGGGATTTTGAGAGGCTGGCCCATCTGTATGACACGCTGCACCG
GGCCTACAGCAAAGTGACCGAGGTCATGCACTCGGGCCGCAGGCTTCTGGGGACCTACTTCCGGGTAGCCTTCTTCGGGCAGGTGAGCCT
CCTGTCCATTCTGCAGACTGTCCTAAGTCCTTT

>1535_1535_9_ACSS1-DOCK9_ACSS1_chr20_25011394_ENST00000542618_DOCK9_chr13_99508285_ENST00000448493_length(amino acids)=451AA_BP=
MLGTGMMHARLQQLGSLDNSLTFNHSYGHSDADVLHQSLLEANIATEVCLTALDTLSLFTLAFKNQLLADHGHNPLMKKVFDVYLCFLQK
HQSETALKNVFTALRSLIYKFPSTFYEGRADMCAALCYEILKCCNSKLSSIRTEASQLLYFLMRNNFDYTGKKSFVRTHLQVIISVSQLI
ADVVGIGGTRFQQSLSIINNCANSDRLIKHTSFSSDVKDLTKRIRTVLMATAQMKEHENDPEMLVDLQYSLAKSYASTPELRKTWLDSMA
RIHVKNGDLSEAAMCYVHVTALVAEYLTRKEAVQWEPPLLPHSHSACLRRSRGGVFRQGCTAFRVITPNIDEEASMMEDVGMQDVHFNED
VLMELLEQCADGLWKAERYELIADIYKLIIPIYEKRRDFERLAHLYDTLHRAYSKVTEVMHSGRRLLGTYFRVAFFGQVSLLSILQTVLS
P

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Fusion Gene PPI Analysis for ACSS1-DOCK9


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneDOCK9chr20:25011394chr13:99508285ENST0000033941632541693_20691233.33333333333332094.0CDC42
TgeneDOCK9chr20:25011394chr13:99508285ENST0000037646032571693_20691232.33333333333332069.0CDC42
TgeneDOCK9chr20:25011394chr13:99508285ENST000004421730331693_206901254.0CDC42


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ACSS1-DOCK9


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ACSS1-DOCK9


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC0005586Bipolar Disorder1PSYGENET