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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:ACSS1-FANCM (FusionGDB2 ID:HG84532TG57697) |
Fusion Gene Summary for ACSS1-FANCM |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ACSS1-FANCM | Fusion gene ID: hg84532tg57697 | Hgene | Tgene | Gene symbol | ACSS1 | FANCM | Gene ID | 84532 | 57697 |
| Gene name | acyl-CoA synthetase short chain family member 1 | FA complementation group M | |
| Synonyms | ACAS2L|ACECS1|AceCS2L | FAAP250|KIAA1596|POF15|SPGF28 | |
| Cytomap | ('ACSS1')('FANCM') 20p11.21 | 14q21.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | acetyl-coenzyme A synthetase 2-like, mitochondrialacetate--CoA ligase 2propionate--CoA ligase | Fanconi anemia group M proteinATP-dependent RNA helicase FANCMFanconi anemia complementation group Mfanconi anemia-associated polypeptide of 250 kDaprotein Hef ortholog | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | . | . | |
| Ensembl transtripts involved in fusion gene | ENST00000323482, ENST00000432802, ENST00000537502, ENST00000542618, ENST00000376726, ENST00000484396, | ||
| Fusion gene scores | * DoF score | 9 X 8 X 7=504 | 3 X 3 X 3=27 |
| # samples | 9 | 3 | |
| ** MAII score | log2(9/504*10)=-2.48542682717024 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: ACSS1 [Title/Abstract] AND FANCM [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | ACSS1(25000646)-FANCM(45628299), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | ACSS1-FANCM seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. ACSS1-FANCM seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. ACSS1-FANCM seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. ACSS1-FANCM seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | ACSS1 | GO:0006085 | acetyl-CoA biosynthetic process | 16788062 |
| Fusion gene breakpoints across ACSS1 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across FANCM (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | Non-Cancer | ERR315367 | ACSS1 | chr20 | 25000646 | - | FANCM | chr14 | 45628299 | + |
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Fusion Gene ORF analysis for ACSS1-FANCM |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000323482 | ENST00000555013 | ACSS1 | chr20 | 25000646 | - | FANCM | chr14 | 45628299 | + |
| 5CDS-intron | ENST00000432802 | ENST00000555013 | ACSS1 | chr20 | 25000646 | - | FANCM | chr14 | 45628299 | + |
| 5CDS-intron | ENST00000537502 | ENST00000555013 | ACSS1 | chr20 | 25000646 | - | FANCM | chr14 | 45628299 | + |
| 5CDS-intron | ENST00000542618 | ENST00000555013 | ACSS1 | chr20 | 25000646 | - | FANCM | chr14 | 45628299 | + |
| In-frame | ENST00000323482 | ENST00000267430 | ACSS1 | chr20 | 25000646 | - | FANCM | chr14 | 45628299 | + |
| In-frame | ENST00000323482 | ENST00000542564 | ACSS1 | chr20 | 25000646 | - | FANCM | chr14 | 45628299 | + |
| In-frame | ENST00000323482 | ENST00000556036 | ACSS1 | chr20 | 25000646 | - | FANCM | chr14 | 45628299 | + |
| In-frame | ENST00000432802 | ENST00000267430 | ACSS1 | chr20 | 25000646 | - | FANCM | chr14 | 45628299 | + |
| In-frame | ENST00000432802 | ENST00000542564 | ACSS1 | chr20 | 25000646 | - | FANCM | chr14 | 45628299 | + |
| In-frame | ENST00000432802 | ENST00000556036 | ACSS1 | chr20 | 25000646 | - | FANCM | chr14 | 45628299 | + |
| In-frame | ENST00000537502 | ENST00000267430 | ACSS1 | chr20 | 25000646 | - | FANCM | chr14 | 45628299 | + |
| In-frame | ENST00000537502 | ENST00000542564 | ACSS1 | chr20 | 25000646 | - | FANCM | chr14 | 45628299 | + |
| In-frame | ENST00000537502 | ENST00000556036 | ACSS1 | chr20 | 25000646 | - | FANCM | chr14 | 45628299 | + |
| In-frame | ENST00000542618 | ENST00000267430 | ACSS1 | chr20 | 25000646 | - | FANCM | chr14 | 45628299 | + |
| In-frame | ENST00000542618 | ENST00000542564 | ACSS1 | chr20 | 25000646 | - | FANCM | chr14 | 45628299 | + |
| In-frame | ENST00000542618 | ENST00000556036 | ACSS1 | chr20 | 25000646 | - | FANCM | chr14 | 45628299 | + |
| intron-3CDS | ENST00000376726 | ENST00000267430 | ACSS1 | chr20 | 25000646 | - | FANCM | chr14 | 45628299 | + |
| intron-3CDS | ENST00000376726 | ENST00000542564 | ACSS1 | chr20 | 25000646 | - | FANCM | chr14 | 45628299 | + |
| intron-3CDS | ENST00000376726 | ENST00000556036 | ACSS1 | chr20 | 25000646 | - | FANCM | chr14 | 45628299 | + |
| intron-3CDS | ENST00000484396 | ENST00000267430 | ACSS1 | chr20 | 25000646 | - | FANCM | chr14 | 45628299 | + |
| intron-3CDS | ENST00000484396 | ENST00000542564 | ACSS1 | chr20 | 25000646 | - | FANCM | chr14 | 45628299 | + |
| intron-3CDS | ENST00000484396 | ENST00000556036 | ACSS1 | chr20 | 25000646 | - | FANCM | chr14 | 45628299 | + |
| intron-intron | ENST00000376726 | ENST00000555013 | ACSS1 | chr20 | 25000646 | - | FANCM | chr14 | 45628299 | + |
| intron-intron | ENST00000484396 | ENST00000555013 | ACSS1 | chr20 | 25000646 | - | FANCM | chr14 | 45628299 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000323482 | ACSS1 | chr20 | 25000646 | - | ENST00000556036 | FANCM | chr14 | 45628299 | + | 2192 | 1326 | 80 | 1939 | 619 |
| ENST00000323482 | ACSS1 | chr20 | 25000646 | - | ENST00000267430 | FANCM | chr14 | 45628299 | + | 6956 | 1326 | 80 | 6076 | 1998 |
| ENST00000323482 | ACSS1 | chr20 | 25000646 | - | ENST00000542564 | FANCM | chr14 | 45628299 | + | 6097 | 1326 | 80 | 6076 | 1998 |
| ENST00000432802 | ACSS1 | chr20 | 25000646 | - | ENST00000556036 | FANCM | chr14 | 45628299 | + | 2990 | 2124 | 878 | 2737 | 619 |
| ENST00000432802 | ACSS1 | chr20 | 25000646 | - | ENST00000267430 | FANCM | chr14 | 45628299 | + | 7754 | 2124 | 878 | 6874 | 1998 |
| ENST00000432802 | ACSS1 | chr20 | 25000646 | - | ENST00000542564 | FANCM | chr14 | 45628299 | + | 6895 | 2124 | 878 | 6874 | 1998 |
| ENST00000537502 | ACSS1 | chr20 | 25000646 | - | ENST00000556036 | FANCM | chr14 | 45628299 | + | 3395 | 2529 | 1532 | 3142 | 536 |
| ENST00000537502 | ACSS1 | chr20 | 25000646 | - | ENST00000267430 | FANCM | chr14 | 45628299 | + | 8159 | 2529 | 1532 | 7279 | 1915 |
| ENST00000537502 | ACSS1 | chr20 | 25000646 | - | ENST00000542564 | FANCM | chr14 | 45628299 | + | 7300 | 2529 | 1532 | 7279 | 1915 |
| ENST00000542618 | ACSS1 | chr20 | 25000646 | - | ENST00000556036 | FANCM | chr14 | 45628299 | + | 2016 | 1150 | 267 | 1763 | 498 |
| ENST00000542618 | ACSS1 | chr20 | 25000646 | - | ENST00000267430 | FANCM | chr14 | 45628299 | + | 6780 | 1150 | 267 | 5900 | 1877 |
| ENST00000542618 | ACSS1 | chr20 | 25000646 | - | ENST00000542564 | FANCM | chr14 | 45628299 | + | 5921 | 1150 | 267 | 5900 | 1877 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000323482 | ENST00000556036 | ACSS1 | chr20 | 25000646 | - | FANCM | chr14 | 45628299 | + | 0.003939123 | 0.9960609 |
| ENST00000323482 | ENST00000267430 | ACSS1 | chr20 | 25000646 | - | FANCM | chr14 | 45628299 | + | 9.59E-05 | 0.99990404 |
| ENST00000323482 | ENST00000542564 | ACSS1 | chr20 | 25000646 | - | FANCM | chr14 | 45628299 | + | 0.000155712 | 0.9998443 |
| ENST00000432802 | ENST00000556036 | ACSS1 | chr20 | 25000646 | - | FANCM | chr14 | 45628299 | + | 0.0082044 | 0.9917956 |
| ENST00000432802 | ENST00000267430 | ACSS1 | chr20 | 25000646 | - | FANCM | chr14 | 45628299 | + | 0.000312338 | 0.9996877 |
| ENST00000432802 | ENST00000542564 | ACSS1 | chr20 | 25000646 | - | FANCM | chr14 | 45628299 | + | 0.000503796 | 0.9994962 |
| ENST00000537502 | ENST00000556036 | ACSS1 | chr20 | 25000646 | - | FANCM | chr14 | 45628299 | + | 0.001542662 | 0.9984573 |
| ENST00000537502 | ENST00000267430 | ACSS1 | chr20 | 25000646 | - | FANCM | chr14 | 45628299 | + | 0.000448593 | 0.99955136 |
| ENST00000537502 | ENST00000542564 | ACSS1 | chr20 | 25000646 | - | FANCM | chr14 | 45628299 | + | 0.000634319 | 0.99936575 |
| ENST00000542618 | ENST00000556036 | ACSS1 | chr20 | 25000646 | - | FANCM | chr14 | 45628299 | + | 0.001938106 | 0.99806184 |
| ENST00000542618 | ENST00000267430 | ACSS1 | chr20 | 25000646 | - | FANCM | chr14 | 45628299 | + | 0.000105685 | 0.99989426 |
| ENST00000542618 | ENST00000542564 | ACSS1 | chr20 | 25000646 | - | FANCM | chr14 | 45628299 | + | 0.000166201 | 0.9998338 |
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Fusion Genomic Features for ACSS1-FANCM |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| ACSS1 | chr20 | 25000645 | - | FANCM | chr14 | 45628298 | + | 0.37454864 | 0.6254514 |
| ACSS1 | chr20 | 25000645 | - | FANCM | chr14 | 45628298 | + | 0.37454864 | 0.6254514 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for ACSS1-FANCM |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr20:25000646/chr14:45628299) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | . |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | ACSS1 | chr20:25000646 | chr14:45628299 | ENST00000323482 | - | 7 | 14 | 45_53 | 415 | 690.0 | Compositional bias | Note=Poly-Ala |
| Hgene | ACSS1 | chr20:25000646 | chr14:45628299 | ENST00000432802 | - | 7 | 12 | 45_53 | 415 | 576.0 | Compositional bias | Note=Poly-Ala |
| Hgene | ACSS1 | chr20:25000646 | chr14:45628299 | ENST00000542618 | - | 6 | 13 | 45_53 | 294 | 569.0 | Compositional bias | Note=Poly-Ala |
| Hgene | ACSS1 | chr20:25000646 | chr14:45628299 | ENST00000323482 | - | 7 | 14 | 224_227 | 415 | 690.0 | Region | Coenzyme A binding |
| Hgene | ACSS1 | chr20:25000646 | chr14:45628299 | ENST00000432802 | - | 7 | 12 | 224_227 | 415 | 576.0 | Region | Coenzyme A binding |
| Hgene | ACSS1 | chr20:25000646 | chr14:45628299 | ENST00000542618 | - | 6 | 13 | 224_227 | 294 | 569.0 | Region | Coenzyme A binding |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | ACSS1 | chr20:25000646 | chr14:45628299 | ENST00000323482 | - | 7 | 14 | 417_419 | 415 | 690.0 | Nucleotide binding | ATP |
| Hgene | ACSS1 | chr20:25000646 | chr14:45628299 | ENST00000323482 | - | 7 | 14 | 441_446 | 415 | 690.0 | Nucleotide binding | ATP |
| Hgene | ACSS1 | chr20:25000646 | chr14:45628299 | ENST00000432802 | - | 7 | 12 | 417_419 | 415 | 576.0 | Nucleotide binding | ATP |
| Hgene | ACSS1 | chr20:25000646 | chr14:45628299 | ENST00000432802 | - | 7 | 12 | 441_446 | 415 | 576.0 | Nucleotide binding | ATP |
| Hgene | ACSS1 | chr20:25000646 | chr14:45628299 | ENST00000542618 | - | 6 | 13 | 417_419 | 294 | 569.0 | Nucleotide binding | ATP |
| Hgene | ACSS1 | chr20:25000646 | chr14:45628299 | ENST00000542618 | - | 6 | 13 | 441_446 | 294 | 569.0 | Nucleotide binding | ATP |
| Tgene | FANCM | chr20:25000646 | chr14:45628299 | ENST00000267430 | 7 | 23 | 452_627 | 465 | 2049.0 | Domain | Helicase C-terminal | |
| Tgene | FANCM | chr20:25000646 | chr14:45628299 | ENST00000267430 | 7 | 23 | 98_266 | 465 | 2049.0 | Domain | Helicase ATP-binding | |
| Tgene | FANCM | chr20:25000646 | chr14:45628299 | ENST00000556036 | 7 | 11 | 452_627 | 465 | 670.0 | Domain | Helicase C-terminal | |
| Tgene | FANCM | chr20:25000646 | chr14:45628299 | ENST00000556036 | 7 | 11 | 98_266 | 465 | 670.0 | Domain | Helicase ATP-binding | |
| Tgene | FANCM | chr20:25000646 | chr14:45628299 | ENST00000267430 | 7 | 23 | 214_217 | 465 | 2049.0 | Motif | DEAH box | |
| Tgene | FANCM | chr20:25000646 | chr14:45628299 | ENST00000556036 | 7 | 11 | 214_217 | 465 | 670.0 | Motif | DEAH box | |
| Tgene | FANCM | chr20:25000646 | chr14:45628299 | ENST00000267430 | 7 | 23 | 111_118 | 465 | 2049.0 | Nucleotide binding | ATP | |
| Tgene | FANCM | chr20:25000646 | chr14:45628299 | ENST00000556036 | 7 | 11 | 111_118 | 465 | 670.0 | Nucleotide binding | ATP |
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Fusion Gene Sequence for ACSS1-FANCM |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >1536_1536_1_ACSS1-FANCM_ACSS1_chr20_25000646_ENST00000323482_FANCM_chr14_45628299_ENST00000267430_length(transcript)=6956nt_BP=1326nt GGCCCGCGGAGACTCCACGGGGCGCCCCGGGCGTGAGGCACCCACTCTGGGAGCACAGAGAGCTCAGGTAGCCTGCCTAGATGGCGGCGC GCACCCTGGGCCGCGGCGTCGGGAGGCTGCTGGGCAGCCTGCGAGGGCTCTCGGGGCAGCCCGCGCGGCCGCCGTGCGGGGTGAGCGCGC CGCGCAGGGCGGCCTCGGGACCCTCGGGCAGCGCTCCCGCAGTTGCAGCAGCAGCAGCACAGCCAGGCTCGTATCCCGCGCTGAGTGCAC AGGCAGCCCGGGAGCCGGCCGCCTTCTGGGGGCCTCTGGCGCGGGACACTCTCGTGTGGGACACCCCCTACCACACCGTCTGGGACTGCG ACTTCAGCACTGGCAAGATCGGCTGGTTCCTGGGAGGCCAGTTAAATGTCTCTGTCAACTGCTTGGACCAGCATGTTCGGAAGTCCCCCG AGAGCGTTGCTTTGATCTGGGAGCGCGATGAGCCTGGAACGGAAGTGAGGATCACCTACAGGGAACTACTGGAGACCACGTGCCGCCTGG CCAACACGCTGAAGAGGCATGGAGTCCACCGTGGGGACCGTGTTGCCATCTACATGCCCGTGTCCCCATTGGCTGTGGCAGCAATGCTGG CCTGTGCCAGGATCGGAGCTGTCCACACAGTCATCTTTGCTGGCTTCAGTGCAGAGTCCTTGGCTGGGAGGATCAATGATGCCAAGTGCA AGGTGGTTATCACCTTCAACCAAGGACTCCGGGGTGGGCGCGTGGTGGAGCTGAAGAAAATAGTGGATGAGGCTGTGAAGCACTGCCCCA CCGTGCAGCATGTCCTGGTGGCTCACAGGACAGACAACAAGGTCCACATGGGGGATCTGGACGTCCCGCTGGAGCAGGAAATGGCCAAGG AGGACCCTGTTTGCGCCCCAGAGAGCATGGGCAGTGAGGACATGCTCTTCATGCTGTACACCTCAGGGAGCACCGGAATGCCCAAGGGCA TCGTCCATACCCAGGCAGGCTACCTGCTCTATGCCGCCCTGACTCACAAGCTTGTGTTTGACCACCAGCCAGGTGACATCTTTGGCTGTG TGGCCGACATCGGTTGGATTACAGGACACAGCTACGTGGTGTATGGGCCTCTCTGCAATGGTGCCACCAGCGTCCTTTTTGAGAGCACCC CAGTTTATCCCAATGCTGGTCGGTACTGGGAGACAGTAGAGAGGTTGAAGATCAATCAGTTCTATGGCGCCCCAACGGCTGTCCGGCTGT TGCTGAAATACGGTGATGCCTGGGTGAAGAAGTATGATCGCTCCTCCCTGCGGACCCTGGGGTCAGCTGAAAACACTACTGAAAAGAAAC GTGATGAGACCCGAGTTATGATCTTCTCTTCATTTCGAGATAGTGTTCAAGAAATTGCAGAAATGCTTTCACAGCATCAGCCAATTATTA GAGTAATGACTTTTGTCGGCCATGCCTCAGGGAAAAGCACGAAGGGTTTTACCCAGAAGGAGCAACTGGAGGTAGTGAAACAGTTTCGTG ACGGTGGTTACAACACGCTGGTTTCTACCTGTGTGGGTGAAGAAGGTTTGGATATAGGAGAAGTTGATCTTATAATATGTTTTGATTCCC AGAAGAGCCCAATTCGTCTTGTACAACGAATGGGTAGAACTGGCCGTAAACGTCAAGGCAGGATAGTTATTATCCTTTCTGAAGGACGAG AGGAACGTATTTATAATCAGAGTCAGTCCAACAAAAGAAGTATATATAAAGCTATTTCAAGTAACAGGCAGGTCCTTCATTTTTACCAAA GAAGTCCACGAATGGTTCCTGATGGAATCAACCCAAAATTACACAAAATGTTCATCACACATGGTGTCTATGAACCAGAGAAGCCTTCTC GGAACTTGCAGCGAAAGTCATCTATCTTTTCCTATAGGGATGGAATGAGGCAAAGTAGCCTAAAGAAAGATTGGTTCTTATCAGAAGAAG AATTTAAATTATGGAACAGACTTTATAGATTAAGGGACAGTGATGAAATTAAAGAGATAACATTGCCTCAAGTTCAGTTTTCTTCTTTAC AAAATGAGGAAAACAAACCAGCTCAAGAATCAACCACTGGAATTCATCAACTCTCTCTCTCTGAATGGAGACTGTGGCAAGATCATCCTT TGCCTACACATCAAGTTGATCACTCAGATCGATGCCGCCATTTTATAGGCCTTATGCAAATGATAGAGGGAATGAGACACGAAGAGGGAG AATGCAGCTATGAATTGGAAGTTGAATCTTATTTACAAATGGAAGATGTTACCTCAACATTTATTGCTCCCAGGAATGAATCTAATAATC TTGCCAGTGACACCTTTATCACTCACAAGAAATCGTCATTTATAAAGAACATAAATCAAGGCAGTTCATCCTCAGTGATAGAATCTGATG AAGAATGTGCTGAAATTGTTAAACAAACTCATATCAAACCTACTAAAATTGTTTCTTTAAAGAAAAAAGTGTCTAAAGAAATAAAAAAAG ATCAGCTTAAAAAAGAAAATAATCACGGTATTATAGATTCTGTAGATAATGACAGAAATTCCACTGTTGAAAATATTTTTCAAGAAGACC TACCAAATGATAAAAGGACATCAGATACAGATGAAATTGCTGCCACATGTACTATTAATGAAAATGTTATTAAAGAACCGTGTGTGTTAT TAACAGAGTGTCAGTTTACAAATAAATCCACTAGTTCACTTGCTGGAAATGTTTTAGATTCTGGTTATAACAGTTTCAATGATGAAAAAT CTGTTTCATCTAACTTATTTCTTCCATTCGAAGAAGAGCTTTATATTGTTAGAACAGATGACCAATTTTATAATTGTCACTCATTGACAA AAGAGGTACTAGCTAATGTAGAGAGATTTTTATCTTATTCTCCTCCGCCTCTCAGTGGACTCTCAGACTTGGAATATGAAATTGCTAAGG GTACTGCACTTGAGAATTTGCTTTTCTTACCCTGTGCAGAGCATTTACGAAGTGATAAATGCACCTGTTTGCTGTCACATTCAGCTGTGA ATTCTCAACAGAATTTAGAATTGAATTCACTTAAATGTATAAATTATCCATCTGAAAAAAGTTGCCTTTATGATATACCTAATGATAATA TTTCTGATGAGCCAAGTCTCTGTGACTGTGATGTACATAAACATAATCAAAATGAAAATTTAGTACCTAACAATCGTGTTCAAATACACA GAAGCCCTGCACAGAATTTAGTTGGAGAGAACAATCATGATGTTGATAACAGTGACCTCCCAGTATTGTCCACTGATCAAGATGAAAGTT TGCTGTTATTTGAAGATGTTAATACAGAGTTCGACGATGTGAGTCTTTCACCCTTGAACAGTAAAAGCGAATCTTTACCTGTGTCAGACA AAACTGCTATTAGTGAAACGCCTCTGGTCTCTCAGTTCTTAATTTCTGATGAACTTTTGTTGGACAATAATTCTGAACTCCAAGATCAAA TCACCCGTGATGCTAATAGTTTTAAATCTCGTGATCAGAGAGGTGTACAGGAAGAAAAAGTGAAGAATCATGAGGATATTTTTGATTGCT CTAGGGATTTATTTTCTGTTACCTTTGATTTAGGATTCTGTAGTCCAGATTCTGATGATGAAATATTGGAACATACATCAGATAGCAATA GACCTCTAGATGATCTATATGGAAGGTATTTGGAAATTAAGGAGATAAGTGATGCAAATTATGTTTCGAATCAAGCACTAATACCAAGAG ATCATAGTAAAAATTTTACTAGTGGAACTGTTATTATCCCATCAAATGAAGATATGCAGAATCCAAATTATGTACATTTGCCACTGAGTG CAGCAAAAAATGAAGAATTGTTATCTCCTGGTTATTCTCAGTTTTCTTTACCAGTGCAAAAAAAAGTTATGAGTACACCACTCTCTAAAT CAAACACATTGAACTCATTTTCTAAGATAAGAAAGGAAATACTTAAGACACCAGATTCTAGTAAGGAAAAAGTAAACCTACAAAGATTCA AAGAAGCATTGAATTCAACTTTTGATTATTCAGAATTTTCTCTAGAAAAGTCTAAAAGCAGTGGTCCAATGTATCTGCATAAATCCTGTC ATTCTGTTGAAGATGGACAATTATTAACAAGTAACGAAAGTGAAGATGACGAGATTTTCCGAAGAAAAGTTAAAAGAGCAAAAGGAAATG TTTTAAACTCTCCTGAGGATCAGAAAAATAGTGAAGTTGATTCTCCACTTCATGCTGTCAAAAAGCGCAGATTTCCTATAAACAGATCAG AATTATCATCTAGTGATGAGAGTGAGAATTTTCCCAAACCATGTTCACAATTAGAAGACTTCAAGGTTTGTAACGGGAATGCCAGAAGAG GCATCAAAGTCCCAAAGAGACAGAGTCACTTAAAGCATGTAGCTAGGAAGTTTTTAGATGATGAAGCAGAACTTTCTGAAGAAGATGCAG AATATGTTTCATCAGATGAAAATGATGAGTCAGAAAATGAACAAGATTCCTCATTACTTGACTTTTTAAATGATGAAACTCAACTTTCAC AGGCTATAAATGATTCTGAAATGAGAGCTATTTACATGAAATCTTTGCGTAGTCCAATGATGAACAATAAGTACAAAATGATTCATAAGA CACATAAAAACATAAACATTTTCTCGCAGATTCCTGAACAAGATGAAACCTATTTAGAGGATAGTTTTTGTGTTGATGAAGAGGAGTCTT GCAAAGGCCAATCAAGTGAAGAAGAAGTTTGTGTTGATTTTAACTTAATAACTGATGATTGCTTTGCAAATAGTAAAAAGTATAAAACTC GACGTGCAGTAATGCTAAAAGAAATGATGGAACAAAATTGTGCACATTCAAAAAAGAAATTATCCAGAATTATTTTACCAGATGATTCAA GTGAGGAGGAGAACAATGTAAATGATAAAAGAGAATCTAATATTGCGGTTAACCCAAGCACTGTTAAGAAGAACAAACAACAGGACCATT GTTTAAATTCAGTGCCTTCTGGATCTTCTGCGCAGTCCAAGGTGCGTTCTACTCCAAGAGTTAATCCATTAGCAAAGCAGAGCAAACAGA CATCGCTGAATTTAAAGGATACAATTTCCGAAGTCTCAGACTTCAAACCTCAGAATCATAATGAAGTCCAGTCTACCACACCACCCTTCA CTACTGTTGATTCACAGAAAGACTGTAGAAAATTTCCAGTTCCACAGAAGGATGGTAGTGCTTTGGAGGATTCTAGCACTTCAGGGGCAT CCTGTTCCAAGTCAAGACCACATTTAGCTGGGACACATACTTCTCTTAGACTTCCGCAGGAAGGAAAAGGAACCTGTATTCTTGTAGGTG GTCATGAAATCACTTCTGGATTAGAAGTAATTTCTTCCCTAAGAGCAATTCATGGGTTGCAAGTAGAAGTTTGTCCTCTTAATGGCTGTG ATTACATCGTGAGTAATCGCATGGTGGTGGAAAGGAGGTCTCAATCTGAGATGTTAAATAGTGTCAATAAGAACAAGTTCATTGAGCAGA TCCAGCACCTGCAGAGTATGTTTGAAAGAATATGTGTGATTGTGGAAAAGGACAGAGAAAAAACAGGAGACACATCAAGGATGTTTAGGA GAACAAAGAGCTATGACAGCCTGCTGACTACCTTAATTGGCGCTGGAATCCGAATTCTTTTCAGTTCCTGCCAAGAAGAAACCGCAGATT TGCTAAAGGAACTGTCTTTAGTGGAACAAAGAAAGAATGTTGGTATTCATGTTCCAACAGTGGTGAATAGTAATAAAAGTGAGGCACTCC AGTTTTATTTAAGTATTCCCAATATAAGTTATATAACTGCATTAAATATGTGTCACCAGTTTTCATCTGTGAAAAGGATGGCTAACAGCT CACTTCAAGAAATCTCCATGTATGCACAAGTAACTCATCAGAAGGCTGAGGAGATCTATAGATATATTCACTATGTATTTGACATACAAA TGTTACCAAATGATCTTAACCAAGATAGACTGAAATCTGATATATAATCAAGCTGCTCAAGATGGGGTTTTCAAAGACCTCTCACAATAT TAAATGCACTTCAATAATCATTGCTGTTTTATGTTTATTTGTAAATAAGAGAATATTTTATTTAAATATTTTATATTGTATACATTTTTA TTTATAGATTATAGAAATTATTAAAAAAGAAAAATCTGATGTTCAGTGATCATTTTGACTAGATTATAAAACTAATTTTTCTTATTAAAT AAAACAAGGTTTATTAAAAGTGTTACTAAGGATAGTTTAAGAAAGTAAAAGCTAAGCTAGAGATATACTTTGGAATGTTTCCCAAAATTA AAGTTGTACTGTTGTGATAAATAGTAAAGTTGACATGTCTATGACTACAGCCAACTTGTCGATTTTCCCTATGTGTAGATAGTATACTTT TAAGTGTACTGATTCTAAATACATGTACTTGGTAAGGTGTGGGTGATGGGTGGGTTGTGAGATAAATGACCCAGTAACTAGGAAAGTAGA AAACTTAACTGAATGTTTATCTGACCAAAGGTGTGTCCCAGTTAAGTACTGTCAAATCTATTAATATGAACTCTGATATGGTTTGGCTGT GTCCCCAACCAAAATCTCATCTTGACTTGTAATCTGAATTATAATCCCAATATATTGGGGAGGGACCTCCTGGAACGTGATTAGCTCATG GGGGCGGTTCCCCCATGCTGTTCTAGTGATAGTTCTCAGAGGATCTGATGGTTTTATAAGCTTTTCCTCTGTTCACTCTGCAGTTCTCTT GCCTACTGCCATGTGGAAAAGGAAACGTTTGCTTCCCCTCCACCATGATTGTAAGTTCCCGAGGCCTCCCCAGCCATGCAGGACTGTGAG >1536_1536_1_ACSS1-FANCM_ACSS1_chr20_25000646_ENST00000323482_FANCM_chr14_45628299_ENST00000267430_length(amino acids)=1998AA_BP=415 MAARTLGRGVGRLLGSLRGLSGQPARPPCGVSAPRRAASGPSGSAPAVAAAAAQPGSYPALSAQAAREPAAFWGPLARDTLVWDTPYHTV WDCDFSTGKIGWFLGGQLNVSVNCLDQHVRKSPESVALIWERDEPGTEVRITYRELLETTCRLANTLKRHGVHRGDRVAIYMPVSPLAVA AMLACARIGAVHTVIFAGFSAESLAGRINDAKCKVVITFNQGLRGGRVVELKKIVDEAVKHCPTVQHVLVAHRTDNKVHMGDLDVPLEQE MAKEDPVCAPESMGSEDMLFMLYTSGSTGMPKGIVHTQAGYLLYAALTHKLVFDHQPGDIFGCVADIGWITGHSYVVYGPLCNGATSVLF ESTPVYPNAGRYWETVERLKINQFYGAPTAVRLLLKYGDAWVKKYDRSSLRTLGSAENTTEKKRDETRVMIFSSFRDSVQEIAEMLSQHQ PIIRVMTFVGHASGKSTKGFTQKEQLEVVKQFRDGGYNTLVSTCVGEEGLDIGEVDLIICFDSQKSPIRLVQRMGRTGRKRQGRIVIILS EGREERIYNQSQSNKRSIYKAISSNRQVLHFYQRSPRMVPDGINPKLHKMFITHGVYEPEKPSRNLQRKSSIFSYRDGMRQSSLKKDWFL SEEEFKLWNRLYRLRDSDEIKEITLPQVQFSSLQNEENKPAQESTTGIHQLSLSEWRLWQDHPLPTHQVDHSDRCRHFIGLMQMIEGMRH EEGECSYELEVESYLQMEDVTSTFIAPRNESNNLASDTFITHKKSSFIKNINQGSSSSVIESDEECAEIVKQTHIKPTKIVSLKKKVSKE IKKDQLKKENNHGIIDSVDNDRNSTVENIFQEDLPNDKRTSDTDEIAATCTINENVIKEPCVLLTECQFTNKSTSSLAGNVLDSGYNSFN DEKSVSSNLFLPFEEELYIVRTDDQFYNCHSLTKEVLANVERFLSYSPPPLSGLSDLEYEIAKGTALENLLFLPCAEHLRSDKCTCLLSH SAVNSQQNLELNSLKCINYPSEKSCLYDIPNDNISDEPSLCDCDVHKHNQNENLVPNNRVQIHRSPAQNLVGENNHDVDNSDLPVLSTDQ DESLLLFEDVNTEFDDVSLSPLNSKSESLPVSDKTAISETPLVSQFLISDELLLDNNSELQDQITRDANSFKSRDQRGVQEEKVKNHEDI FDCSRDLFSVTFDLGFCSPDSDDEILEHTSDSNRPLDDLYGRYLEIKEISDANYVSNQALIPRDHSKNFTSGTVIIPSNEDMQNPNYVHL PLSAAKNEELLSPGYSQFSLPVQKKVMSTPLSKSNTLNSFSKIRKEILKTPDSSKEKVNLQRFKEALNSTFDYSEFSLEKSKSSGPMYLH KSCHSVEDGQLLTSNESEDDEIFRRKVKRAKGNVLNSPEDQKNSEVDSPLHAVKKRRFPINRSELSSSDESENFPKPCSQLEDFKVCNGN ARRGIKVPKRQSHLKHVARKFLDDEAELSEEDAEYVSSDENDESENEQDSSLLDFLNDETQLSQAINDSEMRAIYMKSLRSPMMNNKYKM IHKTHKNINIFSQIPEQDETYLEDSFCVDEEESCKGQSSEEEVCVDFNLITDDCFANSKKYKTRRAVMLKEMMEQNCAHSKKKLSRIILP DDSSEEENNVNDKRESNIAVNPSTVKKNKQQDHCLNSVPSGSSAQSKVRSTPRVNPLAKQSKQTSLNLKDTISEVSDFKPQNHNEVQSTT PPFTTVDSQKDCRKFPVPQKDGSALEDSSTSGASCSKSRPHLAGTHTSLRLPQEGKGTCILVGGHEITSGLEVISSLRAIHGLQVEVCPL NGCDYIVSNRMVVERRSQSEMLNSVNKNKFIEQIQHLQSMFERICVIVEKDREKTGDTSRMFRRTKSYDSLLTTLIGAGIRILFSSCQEE TADLLKELSLVEQRKNVGIHVPTVVNSNKSEALQFYLSIPNISYITALNMCHQFSSVKRMANSSLQEISMYAQVTHQKAEEIYRYIHYVF -------------------------------------------------------------- >1536_1536_2_ACSS1-FANCM_ACSS1_chr20_25000646_ENST00000323482_FANCM_chr14_45628299_ENST00000542564_length(transcript)=6097nt_BP=1326nt GGCCCGCGGAGACTCCACGGGGCGCCCCGGGCGTGAGGCACCCACTCTGGGAGCACAGAGAGCTCAGGTAGCCTGCCTAGATGGCGGCGC GCACCCTGGGCCGCGGCGTCGGGAGGCTGCTGGGCAGCCTGCGAGGGCTCTCGGGGCAGCCCGCGCGGCCGCCGTGCGGGGTGAGCGCGC CGCGCAGGGCGGCCTCGGGACCCTCGGGCAGCGCTCCCGCAGTTGCAGCAGCAGCAGCACAGCCAGGCTCGTATCCCGCGCTGAGTGCAC AGGCAGCCCGGGAGCCGGCCGCCTTCTGGGGGCCTCTGGCGCGGGACACTCTCGTGTGGGACACCCCCTACCACACCGTCTGGGACTGCG ACTTCAGCACTGGCAAGATCGGCTGGTTCCTGGGAGGCCAGTTAAATGTCTCTGTCAACTGCTTGGACCAGCATGTTCGGAAGTCCCCCG AGAGCGTTGCTTTGATCTGGGAGCGCGATGAGCCTGGAACGGAAGTGAGGATCACCTACAGGGAACTACTGGAGACCACGTGCCGCCTGG CCAACACGCTGAAGAGGCATGGAGTCCACCGTGGGGACCGTGTTGCCATCTACATGCCCGTGTCCCCATTGGCTGTGGCAGCAATGCTGG CCTGTGCCAGGATCGGAGCTGTCCACACAGTCATCTTTGCTGGCTTCAGTGCAGAGTCCTTGGCTGGGAGGATCAATGATGCCAAGTGCA AGGTGGTTATCACCTTCAACCAAGGACTCCGGGGTGGGCGCGTGGTGGAGCTGAAGAAAATAGTGGATGAGGCTGTGAAGCACTGCCCCA CCGTGCAGCATGTCCTGGTGGCTCACAGGACAGACAACAAGGTCCACATGGGGGATCTGGACGTCCCGCTGGAGCAGGAAATGGCCAAGG AGGACCCTGTTTGCGCCCCAGAGAGCATGGGCAGTGAGGACATGCTCTTCATGCTGTACACCTCAGGGAGCACCGGAATGCCCAAGGGCA TCGTCCATACCCAGGCAGGCTACCTGCTCTATGCCGCCCTGACTCACAAGCTTGTGTTTGACCACCAGCCAGGTGACATCTTTGGCTGTG TGGCCGACATCGGTTGGATTACAGGACACAGCTACGTGGTGTATGGGCCTCTCTGCAATGGTGCCACCAGCGTCCTTTTTGAGAGCACCC CAGTTTATCCCAATGCTGGTCGGTACTGGGAGACAGTAGAGAGGTTGAAGATCAATCAGTTCTATGGCGCCCCAACGGCTGTCCGGCTGT TGCTGAAATACGGTGATGCCTGGGTGAAGAAGTATGATCGCTCCTCCCTGCGGACCCTGGGGTCAGCTGAAAACACTACTGAAAAGAAAC GTGATGAGACCCGAGTTATGATCTTCTCTTCATTTCGAGATAGTGTTCAAGAAATTGCAGAAATGCTTTCACAGCATCAGCCAATTATTA GAGTAATGACTTTTGTCGGCCATGCCTCAGGGAAAAGCACGAAGGGTTTTACCCAGAAGGAGCAACTGGAGGTAGTGAAACAGTTTCGTG ACGGTGGTTACAACACGCTGGTTTCTACCTGTGTGGGTGAAGAAGGTTTGGATATAGGAGAAGTTGATCTTATAATATGTTTTGATTCCC AGAAGAGCCCAATTCGTCTTGTACAACGAATGGGTAGAACTGGCCGTAAACGTCAAGGCAGGATAGTTATTATCCTTTCTGAAGGACGAG AGGAACGTATTTATAATCAGAGTCAGTCCAACAAAAGAAGTATATATAAAGCTATTTCAAGTAACAGGCAGGTCCTTCATTTTTACCAAA GAAGTCCACGAATGGTTCCTGATGGAATCAACCCAAAATTACACAAAATGTTCATCACACATGGTGTCTATGAACCAGAGAAGCCTTCTC GGAACTTGCAGCGAAAGTCATCTATCTTTTCCTATAGGGATGGAATGAGGCAAAGTAGCCTAAAGAAAGATTGGTTCTTATCAGAAGAAG AATTTAAATTATGGAACAGACTTTATAGATTAAGGGACAGTGATGAAATTAAAGAGATAACATTGCCTCAAGTTCAGTTTTCTTCTTTAC AAAATGAGGAAAACAAACCAGCTCAAGAATCAACCACTGGAATTCATCAACTCTCTCTCTCTGAATGGAGACTGTGGCAAGATCATCCTT TGCCTACACATCAAGTTGATCACTCAGATCGATGCCGCCATTTTATAGGCCTTATGCAAATGATAGAGGGAATGAGACACGAAGAGGGAG AATGCAGCTATGAATTGGAAGTTGAATCTTATTTACAAATGGAAGATGTTACCTCAACATTTATTGCTCCCAGGAATGAATCTAATAATC TTGCCAGTGACACCTTTATCACTCACAAGAAATCGTCATTTATAAAGAACATAAATCAAGGCAGTTCATCCTCAGTGATAGAATCTGATG AAGAATGTGCTGAAATTGTTAAACAAACTCATATCAAACCTACTAAAATTGTTTCTTTAAAGAAAAAAGTGTCTAAAGAAATAAAAAAAG ATCAGCTTAAAAAAGAAAATAATCACGGTATTATAGATTCTGTAGATAATGACAGAAATTCCACTGTTGAAAATATTTTTCAAGAAGACC TACCAAATGATAAAAGGACATCAGATACAGATGAAATTGCTGCCACATGTACTATTAATGAAAATGTTATTAAAGAACCGTGTGTGTTAT TAACAGAGTGTCAGTTTACAAATAAATCCACTAGTTCACTTGCTGGAAATGTTTTAGATTCTGGTTATAACAGTTTCAATGATGAAAAAT CTGTTTCATCTAACTTATTTCTTCCATTCGAAGAAGAGCTTTATATTGTTAGAACAGATGACCAATTTTATAATTGTCACTCATTGACAA AAGAGGTACTAGCTAATGTAGAGAGATTTTTATCTTATTCTCCTCCGCCTCTCAGTGGACTCTCAGACTTGGAATATGAAATTGCTAAGG GTACTGCACTTGAGAATTTGCTTTTCTTACCCTGTGCAGAGCATTTACGAAGTGATAAATGCACCTGTTTGCTGTCACATTCAGCTGTGA ATTCTCAACAGAATTTAGAATTGAATTCACTTAAATGTATAAATTATCCATCTGAAAAAAGTTGCCTTTATGATATACCTAATGATAATA TTTCTGATGAGCCAAGTCTCTGTGACTGTGATGTACATAAACATAATCAAAATGAAAATTTAGTACCTAACAATCGTGTTCAAATACACA GAAGCCCTGCACAGAATTTAGTTGGAGAGAACAATCATGATGTTGATAACAGTGACCTCCCAGTATTGTCCACTGATCAAGATGAAAGTT TGCTGTTATTTGAAGATGTTAATACAGAGTTCGACGATGTGAGTCTTTCACCCTTGAACAGTAAAAGCGAATCTTTACCTGTGTCAGACA AAACTGCTATTAGTGAAACGCCTCTGGTCTCTCAGTTCTTAATTTCTGATGAACTTTTGTTGGACAATAATTCTGAACTCCAAGATCAAA TCACCCGTGATGCTAATAGTTTTAAATCTCGTGATCAGAGAGGTGTACAGGAAGAAAAAGTGAAGAATCATGAGGATATTTTTGATTGCT CTAGGGATTTATTTTCTGTTACCTTTGATTTAGGATTCTGTAGTCCAGATTCTGATGATGAAATATTGGAACATACATCAGATAGCAATA GACCTCTAGATGATCTATATGGAAGGTATTTGGAAATTAAGGAGATAAGTGATGCAAATTATGTTTCGAATCAAGCACTAATACCAAGAG ATCATAGTAAAAATTTTACTAGTGGAACTGTTATTATCCCATCAAATGAAGATATGCAGAATCCAAATTATGTACATTTGCCACTGAGTG CAGCAAAAAATGAAGAATTGTTATCTCCTGGTTATTCTCAGTTTTCTTTACCAGTGCAAAAAAAAGTTATGAGTACACCACTCTCTAAAT CAAACACATTGAACTCATTTTCTAAGATAAGAAAGGAAATACTTAAGACACCAGATTCTAGTAAGGAAAAAGTAAACCTACAAAGATTCA AAGAAGCATTGAATTCAACTTTTGATTATTCAGAATTTTCTCTAGAAAAGTCTAAAAGCAGTGGTCCAATGTATCTGCATAAATCCTGTC ATTCTGTTGAAGATGGACAATTATTAACAAGTAACGAAAGTGAAGATGACGAGATTTTCCGAAGAAAAGTTAAAAGAGCAAAAGGAAATG TTTTAAACTCTCCTGAGGATCAGAAAAATAGTGAAGTTGATTCTCCACTTCATGCTGTCAAAAAGCGCAGATTTCCTATAAACAGATCAG AATTATCATCTAGTGATGAGAGTGAGAATTTTCCCAAACCATGTTCACAATTAGAAGACTTCAAGGTTTGTAACGGGAATGCCAGAAGAG GCATCAAAGTCCCAAAGAGACAGAGTCACTTAAAGCATGTAGCTAGGAAGTTTTTAGATGATGAAGCAGAACTTTCTGAAGAAGATGCAG AATATGTTTCATCAGATGAAAATGATGAGTCAGAAAATGAACAAGATTCCTCATTACTTGACTTTTTAAATGATGAAACTCAACTTTCAC AGGCTATAAATGATTCTGAAATGAGAGCTATTTACATGAAATCTTTGCGTAGTCCAATGATGAACAATAAGTACAAAATGATTCATAAGA CACATAAAAACATAAACATTTTCTCGCAGATTCCTGAACAAGATGAAACCTATTTAGAGGATAGTTTTTGTGTTGATGAAGAGGAGTCTT GCAAAGGCCAATCAAGTGAAGAAGAAGTTTGTGTTGATTTTAACTTAATAACTGATGATTGCTTTGCAAATAGTAAAAAGTATAAAACTC GACGTGCAGTAATGCTAAAAGAAATGATGGAACAAAATTGTGCACATTCAAAAAAGAAATTATCCAGAATTATTTTACCAGATGATTCAA GTGAGGAGGAGAACAATGTAAATGATAAAAGAGAATCTAATATTGCGGTTAACCCAAGCACTGTTAAGAAGAACAAACAACAGGACCATT GTTTAAATTCAGTGCCTTCTGGATCTTCTGCGCAGTCCAAGGTGCGTTCTACTCCAAGAGTTAATCCATTAGCAAAGCAGAGCAAACAGA CATCGCTGAATTTAAAGGATACAATTTCCGAAGTCTCAGACTTCAAACCTCAGAATCATAATGAAGTCCAGTCTACCACACCACCCTTCA CTACTGTTGATTCACAGAAAGACTGTAGAAAATTTCCAGTTCCACAGAAGGATGGTAGTGCTTTGGAGGATTCTAGCACTTCAGGGGCAT CCTGTTCCAAGTCAAGACCACATTTAGCTGGGACACATACTTCTCTTAGACTTCCGCAGGAAGGAAAAGGAACCTGTATTCTTGTAGGTG GTCATGAAATCACTTCTGGATTAGAAGTAATTTCTTCCCTAAGAGCAATTCATGGGTTGCAAGTAGAAGTTTGTCCTCTTAATGGCTGTG ATTACATCGTGAGTAATCGCATGGTGGTGGAAAGGAGGTCTCAATCTGAGATGTTAAATAGTGTCAATAAGAACAAGTTCATTGAGCAGA TCCAGCACCTGCAGAGTATGTTTGAAAGAATATGTGTGATTGTGGAAAAGGACAGAGAAAAAACAGGAGACACATCAAGGATGTTTAGGA GAACAAAGAGCTATGACAGCCTGCTGACTACCTTAATTGGCGCTGGAATCCGAATTCTTTTCAGTTCCTGCCAAGAAGAAACCGCAGATT TGCTAAAGGAACTGTCTTTAGTGGAACAAAGAAAGAATGTTGGTATTCATGTTCCAACAGTGGTGAATAGTAATAAAAGTGAGGCACTCC AGTTTTATTTAAGTATTCCCAATATAAGTTATATAACTGCATTAAATATGTGTCACCAGTTTTCATCTGTGAAAAGGATGGCTAACAGCT CACTTCAAGAAATCTCCATGTATGCACAAGTAACTCATCAGAAGGCTGAGGAGATCTATAGATATATTCACTATGTATTTGACATACAAA >1536_1536_2_ACSS1-FANCM_ACSS1_chr20_25000646_ENST00000323482_FANCM_chr14_45628299_ENST00000542564_length(amino acids)=1998AA_BP=415 MAARTLGRGVGRLLGSLRGLSGQPARPPCGVSAPRRAASGPSGSAPAVAAAAAQPGSYPALSAQAAREPAAFWGPLARDTLVWDTPYHTV WDCDFSTGKIGWFLGGQLNVSVNCLDQHVRKSPESVALIWERDEPGTEVRITYRELLETTCRLANTLKRHGVHRGDRVAIYMPVSPLAVA AMLACARIGAVHTVIFAGFSAESLAGRINDAKCKVVITFNQGLRGGRVVELKKIVDEAVKHCPTVQHVLVAHRTDNKVHMGDLDVPLEQE MAKEDPVCAPESMGSEDMLFMLYTSGSTGMPKGIVHTQAGYLLYAALTHKLVFDHQPGDIFGCVADIGWITGHSYVVYGPLCNGATSVLF ESTPVYPNAGRYWETVERLKINQFYGAPTAVRLLLKYGDAWVKKYDRSSLRTLGSAENTTEKKRDETRVMIFSSFRDSVQEIAEMLSQHQ PIIRVMTFVGHASGKSTKGFTQKEQLEVVKQFRDGGYNTLVSTCVGEEGLDIGEVDLIICFDSQKSPIRLVQRMGRTGRKRQGRIVIILS EGREERIYNQSQSNKRSIYKAISSNRQVLHFYQRSPRMVPDGINPKLHKMFITHGVYEPEKPSRNLQRKSSIFSYRDGMRQSSLKKDWFL SEEEFKLWNRLYRLRDSDEIKEITLPQVQFSSLQNEENKPAQESTTGIHQLSLSEWRLWQDHPLPTHQVDHSDRCRHFIGLMQMIEGMRH EEGECSYELEVESYLQMEDVTSTFIAPRNESNNLASDTFITHKKSSFIKNINQGSSSSVIESDEECAEIVKQTHIKPTKIVSLKKKVSKE IKKDQLKKENNHGIIDSVDNDRNSTVENIFQEDLPNDKRTSDTDEIAATCTINENVIKEPCVLLTECQFTNKSTSSLAGNVLDSGYNSFN DEKSVSSNLFLPFEEELYIVRTDDQFYNCHSLTKEVLANVERFLSYSPPPLSGLSDLEYEIAKGTALENLLFLPCAEHLRSDKCTCLLSH SAVNSQQNLELNSLKCINYPSEKSCLYDIPNDNISDEPSLCDCDVHKHNQNENLVPNNRVQIHRSPAQNLVGENNHDVDNSDLPVLSTDQ DESLLLFEDVNTEFDDVSLSPLNSKSESLPVSDKTAISETPLVSQFLISDELLLDNNSELQDQITRDANSFKSRDQRGVQEEKVKNHEDI FDCSRDLFSVTFDLGFCSPDSDDEILEHTSDSNRPLDDLYGRYLEIKEISDANYVSNQALIPRDHSKNFTSGTVIIPSNEDMQNPNYVHL PLSAAKNEELLSPGYSQFSLPVQKKVMSTPLSKSNTLNSFSKIRKEILKTPDSSKEKVNLQRFKEALNSTFDYSEFSLEKSKSSGPMYLH KSCHSVEDGQLLTSNESEDDEIFRRKVKRAKGNVLNSPEDQKNSEVDSPLHAVKKRRFPINRSELSSSDESENFPKPCSQLEDFKVCNGN ARRGIKVPKRQSHLKHVARKFLDDEAELSEEDAEYVSSDENDESENEQDSSLLDFLNDETQLSQAINDSEMRAIYMKSLRSPMMNNKYKM IHKTHKNINIFSQIPEQDETYLEDSFCVDEEESCKGQSSEEEVCVDFNLITDDCFANSKKYKTRRAVMLKEMMEQNCAHSKKKLSRIILP DDSSEEENNVNDKRESNIAVNPSTVKKNKQQDHCLNSVPSGSSAQSKVRSTPRVNPLAKQSKQTSLNLKDTISEVSDFKPQNHNEVQSTT PPFTTVDSQKDCRKFPVPQKDGSALEDSSTSGASCSKSRPHLAGTHTSLRLPQEGKGTCILVGGHEITSGLEVISSLRAIHGLQVEVCPL NGCDYIVSNRMVVERRSQSEMLNSVNKNKFIEQIQHLQSMFERICVIVEKDREKTGDTSRMFRRTKSYDSLLTTLIGAGIRILFSSCQEE TADLLKELSLVEQRKNVGIHVPTVVNSNKSEALQFYLSIPNISYITALNMCHQFSSVKRMANSSLQEISMYAQVTHQKAEEIYRYIHYVF -------------------------------------------------------------- >1536_1536_3_ACSS1-FANCM_ACSS1_chr20_25000646_ENST00000323482_FANCM_chr14_45628299_ENST00000556036_length(transcript)=2192nt_BP=1326nt GGCCCGCGGAGACTCCACGGGGCGCCCCGGGCGTGAGGCACCCACTCTGGGAGCACAGAGAGCTCAGGTAGCCTGCCTAGATGGCGGCGC GCACCCTGGGCCGCGGCGTCGGGAGGCTGCTGGGCAGCCTGCGAGGGCTCTCGGGGCAGCCCGCGCGGCCGCCGTGCGGGGTGAGCGCGC CGCGCAGGGCGGCCTCGGGACCCTCGGGCAGCGCTCCCGCAGTTGCAGCAGCAGCAGCACAGCCAGGCTCGTATCCCGCGCTGAGTGCAC AGGCAGCCCGGGAGCCGGCCGCCTTCTGGGGGCCTCTGGCGCGGGACACTCTCGTGTGGGACACCCCCTACCACACCGTCTGGGACTGCG ACTTCAGCACTGGCAAGATCGGCTGGTTCCTGGGAGGCCAGTTAAATGTCTCTGTCAACTGCTTGGACCAGCATGTTCGGAAGTCCCCCG AGAGCGTTGCTTTGATCTGGGAGCGCGATGAGCCTGGAACGGAAGTGAGGATCACCTACAGGGAACTACTGGAGACCACGTGCCGCCTGG CCAACACGCTGAAGAGGCATGGAGTCCACCGTGGGGACCGTGTTGCCATCTACATGCCCGTGTCCCCATTGGCTGTGGCAGCAATGCTGG CCTGTGCCAGGATCGGAGCTGTCCACACAGTCATCTTTGCTGGCTTCAGTGCAGAGTCCTTGGCTGGGAGGATCAATGATGCCAAGTGCA AGGTGGTTATCACCTTCAACCAAGGACTCCGGGGTGGGCGCGTGGTGGAGCTGAAGAAAATAGTGGATGAGGCTGTGAAGCACTGCCCCA CCGTGCAGCATGTCCTGGTGGCTCACAGGACAGACAACAAGGTCCACATGGGGGATCTGGACGTCCCGCTGGAGCAGGAAATGGCCAAGG AGGACCCTGTTTGCGCCCCAGAGAGCATGGGCAGTGAGGACATGCTCTTCATGCTGTACACCTCAGGGAGCACCGGAATGCCCAAGGGCA TCGTCCATACCCAGGCAGGCTACCTGCTCTATGCCGCCCTGACTCACAAGCTTGTGTTTGACCACCAGCCAGGTGACATCTTTGGCTGTG TGGCCGACATCGGTTGGATTACAGGACACAGCTACGTGGTGTATGGGCCTCTCTGCAATGGTGCCACCAGCGTCCTTTTTGAGAGCACCC CAGTTTATCCCAATGCTGGTCGGTACTGGGAGACAGTAGAGAGGTTGAAGATCAATCAGTTCTATGGCGCCCCAACGGCTGTCCGGCTGT TGCTGAAATACGGTGATGCCTGGGTGAAGAAGTATGATCGCTCCTCCCTGCGGACCCTGGGGTCAGCTGAAAACACTACTGAAAAGAAAC GTGATGAGACCCGAGTTATGATCTTCTCTTCATTTCGAGATAGTGTTCAAGAAATTGCAGAAATGCTTTCACAGCATCAGCCAATTATTA GAGTAATGACTTTTGTCGGCCATGCCTCAGGGAAAAGCACGAAGGGTTTTACCCAGAAGGAGCAACTGGAGGTAGTGAAACAGTTTCGTG ACGGTGGTTACAACACGCTGGTTTCTACCTGTGTGGGTGAAGAAGGTTTGGATATAGGAGAAGTTGATCTTATAATATGTTTTGATTCCC AGAAGAGCCCAATTCGTCTTGTACAACGAATGGGTAGAACTGGCCGTAAACGTCAAGGCAGGATAGTTATTATCCTTTCTGAAGGACGAG AGGAACGTATTTATAATCAGAGTCAGTCCAACAAAAGAAGTATATATAAAGCTATTTCAAGTAACAGGCAGGTCCTTCATTTTTACCAAA GAAGTCCACGAATGGTTCCTGATGGAATCAACCCAAAATTACACAAAATGTTCATCACACATGGTGTCTATGAACCAGAGAAGCCTTCTC GGAACTTGCAGCGAAAGTCATCTATCTTTTCCTATAGGGATGGTAAATAAATTTTGCATTTGACACATGCATTTTTCCCCTGTTCTTACT TAGCAGGTCGTATCTTGATATAATATTTCTTGTTTGAAAAACTGAATATATGTTCTAATTAATATATTATAGGCATTCTCTTTGGAAAGG CTGTACGAGATTATTCATGTGGCAAATGGAGAGACACTGGTAGTATAGAGTGACAGAAACTCAGTGTTGGGGAAAATTAAACATACCCTA >1536_1536_3_ACSS1-FANCM_ACSS1_chr20_25000646_ENST00000323482_FANCM_chr14_45628299_ENST00000556036_length(amino acids)=619AA_BP=415 MAARTLGRGVGRLLGSLRGLSGQPARPPCGVSAPRRAASGPSGSAPAVAAAAAQPGSYPALSAQAAREPAAFWGPLARDTLVWDTPYHTV WDCDFSTGKIGWFLGGQLNVSVNCLDQHVRKSPESVALIWERDEPGTEVRITYRELLETTCRLANTLKRHGVHRGDRVAIYMPVSPLAVA AMLACARIGAVHTVIFAGFSAESLAGRINDAKCKVVITFNQGLRGGRVVELKKIVDEAVKHCPTVQHVLVAHRTDNKVHMGDLDVPLEQE MAKEDPVCAPESMGSEDMLFMLYTSGSTGMPKGIVHTQAGYLLYAALTHKLVFDHQPGDIFGCVADIGWITGHSYVVYGPLCNGATSVLF ESTPVYPNAGRYWETVERLKINQFYGAPTAVRLLLKYGDAWVKKYDRSSLRTLGSAENTTEKKRDETRVMIFSSFRDSVQEIAEMLSQHQ PIIRVMTFVGHASGKSTKGFTQKEQLEVVKQFRDGGYNTLVSTCVGEEGLDIGEVDLIICFDSQKSPIRLVQRMGRTGRKRQGRIVIILS -------------------------------------------------------------- >1536_1536_4_ACSS1-FANCM_ACSS1_chr20_25000646_ENST00000432802_FANCM_chr14_45628299_ENST00000267430_length(transcript)=7754nt_BP=2124nt AAAAGGAAAACGAGGCACCGAGAAGTTAAGGAACTTGCTCAAGGTCACAGAGTTTGAACTCAGGCTACAGATGCTGCAGCAACTGGAGAA AGTCCTCATCGCCCCATATCACCCACCACCGACCCCCAGCAGGACGTGACCCCCGCCAGGACGGAGGCCGGCAGCTGGGGGGCTGGAGCA TGGGACCCAGAACACGGACTCAGGCTTGCGCAGCCTCCTGGCTTCTAGGCGGGAGCCTAGAAAGGCGCCAGCCCCTTTCGCGTGCTGCTG AGACTCCAGGGGTGGGGTTCACTCTCAGGGGCGCACAAAGGCATGAAAACCTTGGCTTCAGCCTCTGAGATGCGGAACTGACCGACCTAT TGTCTTGGGACCCACCAGTGCGCTTGGGTGCACCAGCCCCCTTAACGTTGGTGCCGGCTCCCTCCCGGCTCCTCCCCATCCCAGAGGGTC CCCTCGCCCCAGGCCCTGAGCCTGCGTCCTGGGGTCCTGGGCCGCACGTGCCTCTGGCAGCTCGAAGAAGCTGTCGGGGCTTGCAGGAGA GCGTGCAAACTGAAACCAAAACAGGCCGACTCGAGGAACATCCGGGTGGGACCGCAGACTCACCGGAGCGCAGCGCCTGGGCCAGGGCCT GGGACCCTGCTCCGCCCCGCGCTCCCCTGCACCCCTTCCCCACGCTGCTCCCCTCTTCCTAAGCGGCCCCCCCTCTCCCGGGCAGCAGAA GAAGGGGTGGGACCCGGGCGGGCTCCGGGAGGGGGCCCTGGAGGAATGGATGGTGGCGGAAGGGCGGAGCAGGGGCGGGGCCCGCGGAGA CTCCACGGGGCGCCCCGGGCGTGAGGCACCCACTCTGGGAGCACAGAGAGCTCAGGTAGCCTGCCTAGATGGCGGCGCGCACCCTGGGCC GCGGCGTCGGGAGGCTGCTGGGCAGCCTGCGAGGGCTCTCGGGGCAGCCCGCGCGGCCGCCGTGCGGGGTGAGCGCGCCGCGCAGGGCGG CCTCGGGACCCTCGGGCAGCGCTCCCGCAGTTGCAGCAGCAGCAGCACAGCCAGGCTCGTATCCCGCGCTGAGTGCACAGGCAGCCCGGG AGCCGGCCGCCTTCTGGGGGCCTCTGGCGCGGGACACTCTCGTGTGGGACACCCCCTACCACACCGTCTGGGACTGCGACTTCAGCACTG GCAAGATCGGCTGGTTCCTGGGAGGCCAGTTAAATGTCTCTGTCAACTGCTTGGACCAGCATGTTCGGAAGTCCCCCGAGAGCGTTGCTT TGATCTGGGAGCGCGATGAGCCTGGAACGGAAGTGAGGATCACCTACAGGGAACTACTGGAGACCACGTGCCGCCTGGCCAACACGCTGA AGAGGCATGGAGTCCACCGTGGGGACCGTGTTGCCATCTACATGCCCGTGTCCCCATTGGCTGTGGCAGCAATGCTGGCCTGTGCCAGGA TCGGAGCTGTCCACACAGTCATCTTTGCTGGCTTCAGTGCAGAGTCCTTGGCTGGGAGGATCAATGATGCCAAGTGCAAGGTGGTTATCA CCTTCAACCAAGGACTCCGGGGTGGGCGCGTGGTGGAGCTGAAGAAAATAGTGGATGAGGCTGTGAAGCACTGCCCCACCGTGCAGCATG TCCTGGTGGCTCACAGGACAGACAACAAGGTCCACATGGGGGATCTGGACGTCCCGCTGGAGCAGGAAATGGCCAAGGAGGACCCTGTTT GCGCCCCAGAGAGCATGGGCAGTGAGGACATGCTCTTCATGCTGTACACCTCAGGGAGCACCGGAATGCCCAAGGGCATCGTCCATACCC AGGCAGGCTACCTGCTCTATGCCGCCCTGACTCACAAGCTTGTGTTTGACCACCAGCCAGGTGACATCTTTGGCTGTGTGGCCGACATCG GTTGGATTACAGGACACAGCTACGTGGTGTATGGGCCTCTCTGCAATGGTGCCACCAGCGTCCTTTTTGAGAGCACCCCAGTTTATCCCA ATGCTGGTCGGTACTGGGAGACAGTAGAGAGGTTGAAGATCAATCAGTTCTATGGCGCCCCAACGGCTGTCCGGCTGTTGCTGAAATACG GTGATGCCTGGGTGAAGAAGTATGATCGCTCCTCCCTGCGGACCCTGGGGTCAGCTGAAAACACTACTGAAAAGAAACGTGATGAGACCC GAGTTATGATCTTCTCTTCATTTCGAGATAGTGTTCAAGAAATTGCAGAAATGCTTTCACAGCATCAGCCAATTATTAGAGTAATGACTT TTGTCGGCCATGCCTCAGGGAAAAGCACGAAGGGTTTTACCCAGAAGGAGCAACTGGAGGTAGTGAAACAGTTTCGTGACGGTGGTTACA ACACGCTGGTTTCTACCTGTGTGGGTGAAGAAGGTTTGGATATAGGAGAAGTTGATCTTATAATATGTTTTGATTCCCAGAAGAGCCCAA TTCGTCTTGTACAACGAATGGGTAGAACTGGCCGTAAACGTCAAGGCAGGATAGTTATTATCCTTTCTGAAGGACGAGAGGAACGTATTT ATAATCAGAGTCAGTCCAACAAAAGAAGTATATATAAAGCTATTTCAAGTAACAGGCAGGTCCTTCATTTTTACCAAAGAAGTCCACGAA TGGTTCCTGATGGAATCAACCCAAAATTACACAAAATGTTCATCACACATGGTGTCTATGAACCAGAGAAGCCTTCTCGGAACTTGCAGC GAAAGTCATCTATCTTTTCCTATAGGGATGGAATGAGGCAAAGTAGCCTAAAGAAAGATTGGTTCTTATCAGAAGAAGAATTTAAATTAT GGAACAGACTTTATAGATTAAGGGACAGTGATGAAATTAAAGAGATAACATTGCCTCAAGTTCAGTTTTCTTCTTTACAAAATGAGGAAA ACAAACCAGCTCAAGAATCAACCACTGGAATTCATCAACTCTCTCTCTCTGAATGGAGACTGTGGCAAGATCATCCTTTGCCTACACATC AAGTTGATCACTCAGATCGATGCCGCCATTTTATAGGCCTTATGCAAATGATAGAGGGAATGAGACACGAAGAGGGAGAATGCAGCTATG AATTGGAAGTTGAATCTTATTTACAAATGGAAGATGTTACCTCAACATTTATTGCTCCCAGGAATGAATCTAATAATCTTGCCAGTGACA CCTTTATCACTCACAAGAAATCGTCATTTATAAAGAACATAAATCAAGGCAGTTCATCCTCAGTGATAGAATCTGATGAAGAATGTGCTG AAATTGTTAAACAAACTCATATCAAACCTACTAAAATTGTTTCTTTAAAGAAAAAAGTGTCTAAAGAAATAAAAAAAGATCAGCTTAAAA AAGAAAATAATCACGGTATTATAGATTCTGTAGATAATGACAGAAATTCCACTGTTGAAAATATTTTTCAAGAAGACCTACCAAATGATA AAAGGACATCAGATACAGATGAAATTGCTGCCACATGTACTATTAATGAAAATGTTATTAAAGAACCGTGTGTGTTATTAACAGAGTGTC AGTTTACAAATAAATCCACTAGTTCACTTGCTGGAAATGTTTTAGATTCTGGTTATAACAGTTTCAATGATGAAAAATCTGTTTCATCTA ACTTATTTCTTCCATTCGAAGAAGAGCTTTATATTGTTAGAACAGATGACCAATTTTATAATTGTCACTCATTGACAAAAGAGGTACTAG CTAATGTAGAGAGATTTTTATCTTATTCTCCTCCGCCTCTCAGTGGACTCTCAGACTTGGAATATGAAATTGCTAAGGGTACTGCACTTG AGAATTTGCTTTTCTTACCCTGTGCAGAGCATTTACGAAGTGATAAATGCACCTGTTTGCTGTCACATTCAGCTGTGAATTCTCAACAGA ATTTAGAATTGAATTCACTTAAATGTATAAATTATCCATCTGAAAAAAGTTGCCTTTATGATATACCTAATGATAATATTTCTGATGAGC CAAGTCTCTGTGACTGTGATGTACATAAACATAATCAAAATGAAAATTTAGTACCTAACAATCGTGTTCAAATACACAGAAGCCCTGCAC AGAATTTAGTTGGAGAGAACAATCATGATGTTGATAACAGTGACCTCCCAGTATTGTCCACTGATCAAGATGAAAGTTTGCTGTTATTTG AAGATGTTAATACAGAGTTCGACGATGTGAGTCTTTCACCCTTGAACAGTAAAAGCGAATCTTTACCTGTGTCAGACAAAACTGCTATTA GTGAAACGCCTCTGGTCTCTCAGTTCTTAATTTCTGATGAACTTTTGTTGGACAATAATTCTGAACTCCAAGATCAAATCACCCGTGATG CTAATAGTTTTAAATCTCGTGATCAGAGAGGTGTACAGGAAGAAAAAGTGAAGAATCATGAGGATATTTTTGATTGCTCTAGGGATTTAT TTTCTGTTACCTTTGATTTAGGATTCTGTAGTCCAGATTCTGATGATGAAATATTGGAACATACATCAGATAGCAATAGACCTCTAGATG ATCTATATGGAAGGTATTTGGAAATTAAGGAGATAAGTGATGCAAATTATGTTTCGAATCAAGCACTAATACCAAGAGATCATAGTAAAA ATTTTACTAGTGGAACTGTTATTATCCCATCAAATGAAGATATGCAGAATCCAAATTATGTACATTTGCCACTGAGTGCAGCAAAAAATG AAGAATTGTTATCTCCTGGTTATTCTCAGTTTTCTTTACCAGTGCAAAAAAAAGTTATGAGTACACCACTCTCTAAATCAAACACATTGA ACTCATTTTCTAAGATAAGAAAGGAAATACTTAAGACACCAGATTCTAGTAAGGAAAAAGTAAACCTACAAAGATTCAAAGAAGCATTGA ATTCAACTTTTGATTATTCAGAATTTTCTCTAGAAAAGTCTAAAAGCAGTGGTCCAATGTATCTGCATAAATCCTGTCATTCTGTTGAAG ATGGACAATTATTAACAAGTAACGAAAGTGAAGATGACGAGATTTTCCGAAGAAAAGTTAAAAGAGCAAAAGGAAATGTTTTAAACTCTC CTGAGGATCAGAAAAATAGTGAAGTTGATTCTCCACTTCATGCTGTCAAAAAGCGCAGATTTCCTATAAACAGATCAGAATTATCATCTA GTGATGAGAGTGAGAATTTTCCCAAACCATGTTCACAATTAGAAGACTTCAAGGTTTGTAACGGGAATGCCAGAAGAGGCATCAAAGTCC CAAAGAGACAGAGTCACTTAAAGCATGTAGCTAGGAAGTTTTTAGATGATGAAGCAGAACTTTCTGAAGAAGATGCAGAATATGTTTCAT CAGATGAAAATGATGAGTCAGAAAATGAACAAGATTCCTCATTACTTGACTTTTTAAATGATGAAACTCAACTTTCACAGGCTATAAATG ATTCTGAAATGAGAGCTATTTACATGAAATCTTTGCGTAGTCCAATGATGAACAATAAGTACAAAATGATTCATAAGACACATAAAAACA TAAACATTTTCTCGCAGATTCCTGAACAAGATGAAACCTATTTAGAGGATAGTTTTTGTGTTGATGAAGAGGAGTCTTGCAAAGGCCAAT CAAGTGAAGAAGAAGTTTGTGTTGATTTTAACTTAATAACTGATGATTGCTTTGCAAATAGTAAAAAGTATAAAACTCGACGTGCAGTAA TGCTAAAAGAAATGATGGAACAAAATTGTGCACATTCAAAAAAGAAATTATCCAGAATTATTTTACCAGATGATTCAAGTGAGGAGGAGA ACAATGTAAATGATAAAAGAGAATCTAATATTGCGGTTAACCCAAGCACTGTTAAGAAGAACAAACAACAGGACCATTGTTTAAATTCAG TGCCTTCTGGATCTTCTGCGCAGTCCAAGGTGCGTTCTACTCCAAGAGTTAATCCATTAGCAAAGCAGAGCAAACAGACATCGCTGAATT TAAAGGATACAATTTCCGAAGTCTCAGACTTCAAACCTCAGAATCATAATGAAGTCCAGTCTACCACACCACCCTTCACTACTGTTGATT CACAGAAAGACTGTAGAAAATTTCCAGTTCCACAGAAGGATGGTAGTGCTTTGGAGGATTCTAGCACTTCAGGGGCATCCTGTTCCAAGT CAAGACCACATTTAGCTGGGACACATACTTCTCTTAGACTTCCGCAGGAAGGAAAAGGAACCTGTATTCTTGTAGGTGGTCATGAAATCA CTTCTGGATTAGAAGTAATTTCTTCCCTAAGAGCAATTCATGGGTTGCAAGTAGAAGTTTGTCCTCTTAATGGCTGTGATTACATCGTGA GTAATCGCATGGTGGTGGAAAGGAGGTCTCAATCTGAGATGTTAAATAGTGTCAATAAGAACAAGTTCATTGAGCAGATCCAGCACCTGC AGAGTATGTTTGAAAGAATATGTGTGATTGTGGAAAAGGACAGAGAAAAAACAGGAGACACATCAAGGATGTTTAGGAGAACAAAGAGCT ATGACAGCCTGCTGACTACCTTAATTGGCGCTGGAATCCGAATTCTTTTCAGTTCCTGCCAAGAAGAAACCGCAGATTTGCTAAAGGAAC TGTCTTTAGTGGAACAAAGAAAGAATGTTGGTATTCATGTTCCAACAGTGGTGAATAGTAATAAAAGTGAGGCACTCCAGTTTTATTTAA GTATTCCCAATATAAGTTATATAACTGCATTAAATATGTGTCACCAGTTTTCATCTGTGAAAAGGATGGCTAACAGCTCACTTCAAGAAA TCTCCATGTATGCACAAGTAACTCATCAGAAGGCTGAGGAGATCTATAGATATATTCACTATGTATTTGACATACAAATGTTACCAAATG ATCTTAACCAAGATAGACTGAAATCTGATATATAATCAAGCTGCTCAAGATGGGGTTTTCAAAGACCTCTCACAATATTAAATGCACTTC AATAATCATTGCTGTTTTATGTTTATTTGTAAATAAGAGAATATTTTATTTAAATATTTTATATTGTATACATTTTTATTTATAGATTAT AGAAATTATTAAAAAAGAAAAATCTGATGTTCAGTGATCATTTTGACTAGATTATAAAACTAATTTTTCTTATTAAATAAAACAAGGTTT ATTAAAAGTGTTACTAAGGATAGTTTAAGAAAGTAAAAGCTAAGCTAGAGATATACTTTGGAATGTTTCCCAAAATTAAAGTTGTACTGT TGTGATAAATAGTAAAGTTGACATGTCTATGACTACAGCCAACTTGTCGATTTTCCCTATGTGTAGATAGTATACTTTTAAGTGTACTGA TTCTAAATACATGTACTTGGTAAGGTGTGGGTGATGGGTGGGTTGTGAGATAAATGACCCAGTAACTAGGAAAGTAGAAAACTTAACTGA ATGTTTATCTGACCAAAGGTGTGTCCCAGTTAAGTACTGTCAAATCTATTAATATGAACTCTGATATGGTTTGGCTGTGTCCCCAACCAA AATCTCATCTTGACTTGTAATCTGAATTATAATCCCAATATATTGGGGAGGGACCTCCTGGAACGTGATTAGCTCATGGGGGCGGTTCCC CCATGCTGTTCTAGTGATAGTTCTCAGAGGATCTGATGGTTTTATAAGCTTTTCCTCTGTTCACTCTGCAGTTCTCTTGCCTACTGCCAT GTGGAAAAGGAAACGTTTGCTTCCCCTCCACCATGATTGTAAGTTCCCGAGGCCTCCCCAGCCATGCAGGACTGTGAGTCAATTAAACAT >1536_1536_4_ACSS1-FANCM_ACSS1_chr20_25000646_ENST00000432802_FANCM_chr14_45628299_ENST00000267430_length(amino acids)=1998AA_BP=415 MAARTLGRGVGRLLGSLRGLSGQPARPPCGVSAPRRAASGPSGSAPAVAAAAAQPGSYPALSAQAAREPAAFWGPLARDTLVWDTPYHTV WDCDFSTGKIGWFLGGQLNVSVNCLDQHVRKSPESVALIWERDEPGTEVRITYRELLETTCRLANTLKRHGVHRGDRVAIYMPVSPLAVA AMLACARIGAVHTVIFAGFSAESLAGRINDAKCKVVITFNQGLRGGRVVELKKIVDEAVKHCPTVQHVLVAHRTDNKVHMGDLDVPLEQE MAKEDPVCAPESMGSEDMLFMLYTSGSTGMPKGIVHTQAGYLLYAALTHKLVFDHQPGDIFGCVADIGWITGHSYVVYGPLCNGATSVLF ESTPVYPNAGRYWETVERLKINQFYGAPTAVRLLLKYGDAWVKKYDRSSLRTLGSAENTTEKKRDETRVMIFSSFRDSVQEIAEMLSQHQ PIIRVMTFVGHASGKSTKGFTQKEQLEVVKQFRDGGYNTLVSTCVGEEGLDIGEVDLIICFDSQKSPIRLVQRMGRTGRKRQGRIVIILS EGREERIYNQSQSNKRSIYKAISSNRQVLHFYQRSPRMVPDGINPKLHKMFITHGVYEPEKPSRNLQRKSSIFSYRDGMRQSSLKKDWFL SEEEFKLWNRLYRLRDSDEIKEITLPQVQFSSLQNEENKPAQESTTGIHQLSLSEWRLWQDHPLPTHQVDHSDRCRHFIGLMQMIEGMRH EEGECSYELEVESYLQMEDVTSTFIAPRNESNNLASDTFITHKKSSFIKNINQGSSSSVIESDEECAEIVKQTHIKPTKIVSLKKKVSKE IKKDQLKKENNHGIIDSVDNDRNSTVENIFQEDLPNDKRTSDTDEIAATCTINENVIKEPCVLLTECQFTNKSTSSLAGNVLDSGYNSFN DEKSVSSNLFLPFEEELYIVRTDDQFYNCHSLTKEVLANVERFLSYSPPPLSGLSDLEYEIAKGTALENLLFLPCAEHLRSDKCTCLLSH SAVNSQQNLELNSLKCINYPSEKSCLYDIPNDNISDEPSLCDCDVHKHNQNENLVPNNRVQIHRSPAQNLVGENNHDVDNSDLPVLSTDQ DESLLLFEDVNTEFDDVSLSPLNSKSESLPVSDKTAISETPLVSQFLISDELLLDNNSELQDQITRDANSFKSRDQRGVQEEKVKNHEDI FDCSRDLFSVTFDLGFCSPDSDDEILEHTSDSNRPLDDLYGRYLEIKEISDANYVSNQALIPRDHSKNFTSGTVIIPSNEDMQNPNYVHL PLSAAKNEELLSPGYSQFSLPVQKKVMSTPLSKSNTLNSFSKIRKEILKTPDSSKEKVNLQRFKEALNSTFDYSEFSLEKSKSSGPMYLH KSCHSVEDGQLLTSNESEDDEIFRRKVKRAKGNVLNSPEDQKNSEVDSPLHAVKKRRFPINRSELSSSDESENFPKPCSQLEDFKVCNGN ARRGIKVPKRQSHLKHVARKFLDDEAELSEEDAEYVSSDENDESENEQDSSLLDFLNDETQLSQAINDSEMRAIYMKSLRSPMMNNKYKM IHKTHKNINIFSQIPEQDETYLEDSFCVDEEESCKGQSSEEEVCVDFNLITDDCFANSKKYKTRRAVMLKEMMEQNCAHSKKKLSRIILP DDSSEEENNVNDKRESNIAVNPSTVKKNKQQDHCLNSVPSGSSAQSKVRSTPRVNPLAKQSKQTSLNLKDTISEVSDFKPQNHNEVQSTT PPFTTVDSQKDCRKFPVPQKDGSALEDSSTSGASCSKSRPHLAGTHTSLRLPQEGKGTCILVGGHEITSGLEVISSLRAIHGLQVEVCPL NGCDYIVSNRMVVERRSQSEMLNSVNKNKFIEQIQHLQSMFERICVIVEKDREKTGDTSRMFRRTKSYDSLLTTLIGAGIRILFSSCQEE TADLLKELSLVEQRKNVGIHVPTVVNSNKSEALQFYLSIPNISYITALNMCHQFSSVKRMANSSLQEISMYAQVTHQKAEEIYRYIHYVF -------------------------------------------------------------- >1536_1536_5_ACSS1-FANCM_ACSS1_chr20_25000646_ENST00000432802_FANCM_chr14_45628299_ENST00000542564_length(transcript)=6895nt_BP=2124nt AAAAGGAAAACGAGGCACCGAGAAGTTAAGGAACTTGCTCAAGGTCACAGAGTTTGAACTCAGGCTACAGATGCTGCAGCAACTGGAGAA AGTCCTCATCGCCCCATATCACCCACCACCGACCCCCAGCAGGACGTGACCCCCGCCAGGACGGAGGCCGGCAGCTGGGGGGCTGGAGCA TGGGACCCAGAACACGGACTCAGGCTTGCGCAGCCTCCTGGCTTCTAGGCGGGAGCCTAGAAAGGCGCCAGCCCCTTTCGCGTGCTGCTG AGACTCCAGGGGTGGGGTTCACTCTCAGGGGCGCACAAAGGCATGAAAACCTTGGCTTCAGCCTCTGAGATGCGGAACTGACCGACCTAT TGTCTTGGGACCCACCAGTGCGCTTGGGTGCACCAGCCCCCTTAACGTTGGTGCCGGCTCCCTCCCGGCTCCTCCCCATCCCAGAGGGTC CCCTCGCCCCAGGCCCTGAGCCTGCGTCCTGGGGTCCTGGGCCGCACGTGCCTCTGGCAGCTCGAAGAAGCTGTCGGGGCTTGCAGGAGA GCGTGCAAACTGAAACCAAAACAGGCCGACTCGAGGAACATCCGGGTGGGACCGCAGACTCACCGGAGCGCAGCGCCTGGGCCAGGGCCT GGGACCCTGCTCCGCCCCGCGCTCCCCTGCACCCCTTCCCCACGCTGCTCCCCTCTTCCTAAGCGGCCCCCCCTCTCCCGGGCAGCAGAA GAAGGGGTGGGACCCGGGCGGGCTCCGGGAGGGGGCCCTGGAGGAATGGATGGTGGCGGAAGGGCGGAGCAGGGGCGGGGCCCGCGGAGA CTCCACGGGGCGCCCCGGGCGTGAGGCACCCACTCTGGGAGCACAGAGAGCTCAGGTAGCCTGCCTAGATGGCGGCGCGCACCCTGGGCC GCGGCGTCGGGAGGCTGCTGGGCAGCCTGCGAGGGCTCTCGGGGCAGCCCGCGCGGCCGCCGTGCGGGGTGAGCGCGCCGCGCAGGGCGG CCTCGGGACCCTCGGGCAGCGCTCCCGCAGTTGCAGCAGCAGCAGCACAGCCAGGCTCGTATCCCGCGCTGAGTGCACAGGCAGCCCGGG AGCCGGCCGCCTTCTGGGGGCCTCTGGCGCGGGACACTCTCGTGTGGGACACCCCCTACCACACCGTCTGGGACTGCGACTTCAGCACTG GCAAGATCGGCTGGTTCCTGGGAGGCCAGTTAAATGTCTCTGTCAACTGCTTGGACCAGCATGTTCGGAAGTCCCCCGAGAGCGTTGCTT TGATCTGGGAGCGCGATGAGCCTGGAACGGAAGTGAGGATCACCTACAGGGAACTACTGGAGACCACGTGCCGCCTGGCCAACACGCTGA AGAGGCATGGAGTCCACCGTGGGGACCGTGTTGCCATCTACATGCCCGTGTCCCCATTGGCTGTGGCAGCAATGCTGGCCTGTGCCAGGA TCGGAGCTGTCCACACAGTCATCTTTGCTGGCTTCAGTGCAGAGTCCTTGGCTGGGAGGATCAATGATGCCAAGTGCAAGGTGGTTATCA CCTTCAACCAAGGACTCCGGGGTGGGCGCGTGGTGGAGCTGAAGAAAATAGTGGATGAGGCTGTGAAGCACTGCCCCACCGTGCAGCATG TCCTGGTGGCTCACAGGACAGACAACAAGGTCCACATGGGGGATCTGGACGTCCCGCTGGAGCAGGAAATGGCCAAGGAGGACCCTGTTT GCGCCCCAGAGAGCATGGGCAGTGAGGACATGCTCTTCATGCTGTACACCTCAGGGAGCACCGGAATGCCCAAGGGCATCGTCCATACCC AGGCAGGCTACCTGCTCTATGCCGCCCTGACTCACAAGCTTGTGTTTGACCACCAGCCAGGTGACATCTTTGGCTGTGTGGCCGACATCG GTTGGATTACAGGACACAGCTACGTGGTGTATGGGCCTCTCTGCAATGGTGCCACCAGCGTCCTTTTTGAGAGCACCCCAGTTTATCCCA ATGCTGGTCGGTACTGGGAGACAGTAGAGAGGTTGAAGATCAATCAGTTCTATGGCGCCCCAACGGCTGTCCGGCTGTTGCTGAAATACG GTGATGCCTGGGTGAAGAAGTATGATCGCTCCTCCCTGCGGACCCTGGGGTCAGCTGAAAACACTACTGAAAAGAAACGTGATGAGACCC GAGTTATGATCTTCTCTTCATTTCGAGATAGTGTTCAAGAAATTGCAGAAATGCTTTCACAGCATCAGCCAATTATTAGAGTAATGACTT TTGTCGGCCATGCCTCAGGGAAAAGCACGAAGGGTTTTACCCAGAAGGAGCAACTGGAGGTAGTGAAACAGTTTCGTGACGGTGGTTACA ACACGCTGGTTTCTACCTGTGTGGGTGAAGAAGGTTTGGATATAGGAGAAGTTGATCTTATAATATGTTTTGATTCCCAGAAGAGCCCAA TTCGTCTTGTACAACGAATGGGTAGAACTGGCCGTAAACGTCAAGGCAGGATAGTTATTATCCTTTCTGAAGGACGAGAGGAACGTATTT ATAATCAGAGTCAGTCCAACAAAAGAAGTATATATAAAGCTATTTCAAGTAACAGGCAGGTCCTTCATTTTTACCAAAGAAGTCCACGAA TGGTTCCTGATGGAATCAACCCAAAATTACACAAAATGTTCATCACACATGGTGTCTATGAACCAGAGAAGCCTTCTCGGAACTTGCAGC GAAAGTCATCTATCTTTTCCTATAGGGATGGAATGAGGCAAAGTAGCCTAAAGAAAGATTGGTTCTTATCAGAAGAAGAATTTAAATTAT GGAACAGACTTTATAGATTAAGGGACAGTGATGAAATTAAAGAGATAACATTGCCTCAAGTTCAGTTTTCTTCTTTACAAAATGAGGAAA ACAAACCAGCTCAAGAATCAACCACTGGAATTCATCAACTCTCTCTCTCTGAATGGAGACTGTGGCAAGATCATCCTTTGCCTACACATC AAGTTGATCACTCAGATCGATGCCGCCATTTTATAGGCCTTATGCAAATGATAGAGGGAATGAGACACGAAGAGGGAGAATGCAGCTATG AATTGGAAGTTGAATCTTATTTACAAATGGAAGATGTTACCTCAACATTTATTGCTCCCAGGAATGAATCTAATAATCTTGCCAGTGACA CCTTTATCACTCACAAGAAATCGTCATTTATAAAGAACATAAATCAAGGCAGTTCATCCTCAGTGATAGAATCTGATGAAGAATGTGCTG AAATTGTTAAACAAACTCATATCAAACCTACTAAAATTGTTTCTTTAAAGAAAAAAGTGTCTAAAGAAATAAAAAAAGATCAGCTTAAAA AAGAAAATAATCACGGTATTATAGATTCTGTAGATAATGACAGAAATTCCACTGTTGAAAATATTTTTCAAGAAGACCTACCAAATGATA AAAGGACATCAGATACAGATGAAATTGCTGCCACATGTACTATTAATGAAAATGTTATTAAAGAACCGTGTGTGTTATTAACAGAGTGTC AGTTTACAAATAAATCCACTAGTTCACTTGCTGGAAATGTTTTAGATTCTGGTTATAACAGTTTCAATGATGAAAAATCTGTTTCATCTA ACTTATTTCTTCCATTCGAAGAAGAGCTTTATATTGTTAGAACAGATGACCAATTTTATAATTGTCACTCATTGACAAAAGAGGTACTAG CTAATGTAGAGAGATTTTTATCTTATTCTCCTCCGCCTCTCAGTGGACTCTCAGACTTGGAATATGAAATTGCTAAGGGTACTGCACTTG AGAATTTGCTTTTCTTACCCTGTGCAGAGCATTTACGAAGTGATAAATGCACCTGTTTGCTGTCACATTCAGCTGTGAATTCTCAACAGA ATTTAGAATTGAATTCACTTAAATGTATAAATTATCCATCTGAAAAAAGTTGCCTTTATGATATACCTAATGATAATATTTCTGATGAGC CAAGTCTCTGTGACTGTGATGTACATAAACATAATCAAAATGAAAATTTAGTACCTAACAATCGTGTTCAAATACACAGAAGCCCTGCAC AGAATTTAGTTGGAGAGAACAATCATGATGTTGATAACAGTGACCTCCCAGTATTGTCCACTGATCAAGATGAAAGTTTGCTGTTATTTG AAGATGTTAATACAGAGTTCGACGATGTGAGTCTTTCACCCTTGAACAGTAAAAGCGAATCTTTACCTGTGTCAGACAAAACTGCTATTA GTGAAACGCCTCTGGTCTCTCAGTTCTTAATTTCTGATGAACTTTTGTTGGACAATAATTCTGAACTCCAAGATCAAATCACCCGTGATG CTAATAGTTTTAAATCTCGTGATCAGAGAGGTGTACAGGAAGAAAAAGTGAAGAATCATGAGGATATTTTTGATTGCTCTAGGGATTTAT TTTCTGTTACCTTTGATTTAGGATTCTGTAGTCCAGATTCTGATGATGAAATATTGGAACATACATCAGATAGCAATAGACCTCTAGATG ATCTATATGGAAGGTATTTGGAAATTAAGGAGATAAGTGATGCAAATTATGTTTCGAATCAAGCACTAATACCAAGAGATCATAGTAAAA ATTTTACTAGTGGAACTGTTATTATCCCATCAAATGAAGATATGCAGAATCCAAATTATGTACATTTGCCACTGAGTGCAGCAAAAAATG AAGAATTGTTATCTCCTGGTTATTCTCAGTTTTCTTTACCAGTGCAAAAAAAAGTTATGAGTACACCACTCTCTAAATCAAACACATTGA ACTCATTTTCTAAGATAAGAAAGGAAATACTTAAGACACCAGATTCTAGTAAGGAAAAAGTAAACCTACAAAGATTCAAAGAAGCATTGA ATTCAACTTTTGATTATTCAGAATTTTCTCTAGAAAAGTCTAAAAGCAGTGGTCCAATGTATCTGCATAAATCCTGTCATTCTGTTGAAG ATGGACAATTATTAACAAGTAACGAAAGTGAAGATGACGAGATTTTCCGAAGAAAAGTTAAAAGAGCAAAAGGAAATGTTTTAAACTCTC CTGAGGATCAGAAAAATAGTGAAGTTGATTCTCCACTTCATGCTGTCAAAAAGCGCAGATTTCCTATAAACAGATCAGAATTATCATCTA GTGATGAGAGTGAGAATTTTCCCAAACCATGTTCACAATTAGAAGACTTCAAGGTTTGTAACGGGAATGCCAGAAGAGGCATCAAAGTCC CAAAGAGACAGAGTCACTTAAAGCATGTAGCTAGGAAGTTTTTAGATGATGAAGCAGAACTTTCTGAAGAAGATGCAGAATATGTTTCAT CAGATGAAAATGATGAGTCAGAAAATGAACAAGATTCCTCATTACTTGACTTTTTAAATGATGAAACTCAACTTTCACAGGCTATAAATG ATTCTGAAATGAGAGCTATTTACATGAAATCTTTGCGTAGTCCAATGATGAACAATAAGTACAAAATGATTCATAAGACACATAAAAACA TAAACATTTTCTCGCAGATTCCTGAACAAGATGAAACCTATTTAGAGGATAGTTTTTGTGTTGATGAAGAGGAGTCTTGCAAAGGCCAAT CAAGTGAAGAAGAAGTTTGTGTTGATTTTAACTTAATAACTGATGATTGCTTTGCAAATAGTAAAAAGTATAAAACTCGACGTGCAGTAA TGCTAAAAGAAATGATGGAACAAAATTGTGCACATTCAAAAAAGAAATTATCCAGAATTATTTTACCAGATGATTCAAGTGAGGAGGAGA ACAATGTAAATGATAAAAGAGAATCTAATATTGCGGTTAACCCAAGCACTGTTAAGAAGAACAAACAACAGGACCATTGTTTAAATTCAG TGCCTTCTGGATCTTCTGCGCAGTCCAAGGTGCGTTCTACTCCAAGAGTTAATCCATTAGCAAAGCAGAGCAAACAGACATCGCTGAATT TAAAGGATACAATTTCCGAAGTCTCAGACTTCAAACCTCAGAATCATAATGAAGTCCAGTCTACCACACCACCCTTCACTACTGTTGATT CACAGAAAGACTGTAGAAAATTTCCAGTTCCACAGAAGGATGGTAGTGCTTTGGAGGATTCTAGCACTTCAGGGGCATCCTGTTCCAAGT CAAGACCACATTTAGCTGGGACACATACTTCTCTTAGACTTCCGCAGGAAGGAAAAGGAACCTGTATTCTTGTAGGTGGTCATGAAATCA CTTCTGGATTAGAAGTAATTTCTTCCCTAAGAGCAATTCATGGGTTGCAAGTAGAAGTTTGTCCTCTTAATGGCTGTGATTACATCGTGA GTAATCGCATGGTGGTGGAAAGGAGGTCTCAATCTGAGATGTTAAATAGTGTCAATAAGAACAAGTTCATTGAGCAGATCCAGCACCTGC AGAGTATGTTTGAAAGAATATGTGTGATTGTGGAAAAGGACAGAGAAAAAACAGGAGACACATCAAGGATGTTTAGGAGAACAAAGAGCT ATGACAGCCTGCTGACTACCTTAATTGGCGCTGGAATCCGAATTCTTTTCAGTTCCTGCCAAGAAGAAACCGCAGATTTGCTAAAGGAAC TGTCTTTAGTGGAACAAAGAAAGAATGTTGGTATTCATGTTCCAACAGTGGTGAATAGTAATAAAAGTGAGGCACTCCAGTTTTATTTAA GTATTCCCAATATAAGTTATATAACTGCATTAAATATGTGTCACCAGTTTTCATCTGTGAAAAGGATGGCTAACAGCTCACTTCAAGAAA TCTCCATGTATGCACAAGTAACTCATCAGAAGGCTGAGGAGATCTATAGATATATTCACTATGTATTTGACATACAAATGTTACCAAATG >1536_1536_5_ACSS1-FANCM_ACSS1_chr20_25000646_ENST00000432802_FANCM_chr14_45628299_ENST00000542564_length(amino acids)=1998AA_BP=415 MAARTLGRGVGRLLGSLRGLSGQPARPPCGVSAPRRAASGPSGSAPAVAAAAAQPGSYPALSAQAAREPAAFWGPLARDTLVWDTPYHTV WDCDFSTGKIGWFLGGQLNVSVNCLDQHVRKSPESVALIWERDEPGTEVRITYRELLETTCRLANTLKRHGVHRGDRVAIYMPVSPLAVA AMLACARIGAVHTVIFAGFSAESLAGRINDAKCKVVITFNQGLRGGRVVELKKIVDEAVKHCPTVQHVLVAHRTDNKVHMGDLDVPLEQE MAKEDPVCAPESMGSEDMLFMLYTSGSTGMPKGIVHTQAGYLLYAALTHKLVFDHQPGDIFGCVADIGWITGHSYVVYGPLCNGATSVLF ESTPVYPNAGRYWETVERLKINQFYGAPTAVRLLLKYGDAWVKKYDRSSLRTLGSAENTTEKKRDETRVMIFSSFRDSVQEIAEMLSQHQ PIIRVMTFVGHASGKSTKGFTQKEQLEVVKQFRDGGYNTLVSTCVGEEGLDIGEVDLIICFDSQKSPIRLVQRMGRTGRKRQGRIVIILS EGREERIYNQSQSNKRSIYKAISSNRQVLHFYQRSPRMVPDGINPKLHKMFITHGVYEPEKPSRNLQRKSSIFSYRDGMRQSSLKKDWFL SEEEFKLWNRLYRLRDSDEIKEITLPQVQFSSLQNEENKPAQESTTGIHQLSLSEWRLWQDHPLPTHQVDHSDRCRHFIGLMQMIEGMRH EEGECSYELEVESYLQMEDVTSTFIAPRNESNNLASDTFITHKKSSFIKNINQGSSSSVIESDEECAEIVKQTHIKPTKIVSLKKKVSKE IKKDQLKKENNHGIIDSVDNDRNSTVENIFQEDLPNDKRTSDTDEIAATCTINENVIKEPCVLLTECQFTNKSTSSLAGNVLDSGYNSFN DEKSVSSNLFLPFEEELYIVRTDDQFYNCHSLTKEVLANVERFLSYSPPPLSGLSDLEYEIAKGTALENLLFLPCAEHLRSDKCTCLLSH SAVNSQQNLELNSLKCINYPSEKSCLYDIPNDNISDEPSLCDCDVHKHNQNENLVPNNRVQIHRSPAQNLVGENNHDVDNSDLPVLSTDQ DESLLLFEDVNTEFDDVSLSPLNSKSESLPVSDKTAISETPLVSQFLISDELLLDNNSELQDQITRDANSFKSRDQRGVQEEKVKNHEDI FDCSRDLFSVTFDLGFCSPDSDDEILEHTSDSNRPLDDLYGRYLEIKEISDANYVSNQALIPRDHSKNFTSGTVIIPSNEDMQNPNYVHL PLSAAKNEELLSPGYSQFSLPVQKKVMSTPLSKSNTLNSFSKIRKEILKTPDSSKEKVNLQRFKEALNSTFDYSEFSLEKSKSSGPMYLH KSCHSVEDGQLLTSNESEDDEIFRRKVKRAKGNVLNSPEDQKNSEVDSPLHAVKKRRFPINRSELSSSDESENFPKPCSQLEDFKVCNGN ARRGIKVPKRQSHLKHVARKFLDDEAELSEEDAEYVSSDENDESENEQDSSLLDFLNDETQLSQAINDSEMRAIYMKSLRSPMMNNKYKM IHKTHKNINIFSQIPEQDETYLEDSFCVDEEESCKGQSSEEEVCVDFNLITDDCFANSKKYKTRRAVMLKEMMEQNCAHSKKKLSRIILP DDSSEEENNVNDKRESNIAVNPSTVKKNKQQDHCLNSVPSGSSAQSKVRSTPRVNPLAKQSKQTSLNLKDTISEVSDFKPQNHNEVQSTT PPFTTVDSQKDCRKFPVPQKDGSALEDSSTSGASCSKSRPHLAGTHTSLRLPQEGKGTCILVGGHEITSGLEVISSLRAIHGLQVEVCPL NGCDYIVSNRMVVERRSQSEMLNSVNKNKFIEQIQHLQSMFERICVIVEKDREKTGDTSRMFRRTKSYDSLLTTLIGAGIRILFSSCQEE TADLLKELSLVEQRKNVGIHVPTVVNSNKSEALQFYLSIPNISYITALNMCHQFSSVKRMANSSLQEISMYAQVTHQKAEEIYRYIHYVF -------------------------------------------------------------- >1536_1536_6_ACSS1-FANCM_ACSS1_chr20_25000646_ENST00000432802_FANCM_chr14_45628299_ENST00000556036_length(transcript)=2990nt_BP=2124nt AAAAGGAAAACGAGGCACCGAGAAGTTAAGGAACTTGCTCAAGGTCACAGAGTTTGAACTCAGGCTACAGATGCTGCAGCAACTGGAGAA AGTCCTCATCGCCCCATATCACCCACCACCGACCCCCAGCAGGACGTGACCCCCGCCAGGACGGAGGCCGGCAGCTGGGGGGCTGGAGCA TGGGACCCAGAACACGGACTCAGGCTTGCGCAGCCTCCTGGCTTCTAGGCGGGAGCCTAGAAAGGCGCCAGCCCCTTTCGCGTGCTGCTG AGACTCCAGGGGTGGGGTTCACTCTCAGGGGCGCACAAAGGCATGAAAACCTTGGCTTCAGCCTCTGAGATGCGGAACTGACCGACCTAT TGTCTTGGGACCCACCAGTGCGCTTGGGTGCACCAGCCCCCTTAACGTTGGTGCCGGCTCCCTCCCGGCTCCTCCCCATCCCAGAGGGTC CCCTCGCCCCAGGCCCTGAGCCTGCGTCCTGGGGTCCTGGGCCGCACGTGCCTCTGGCAGCTCGAAGAAGCTGTCGGGGCTTGCAGGAGA GCGTGCAAACTGAAACCAAAACAGGCCGACTCGAGGAACATCCGGGTGGGACCGCAGACTCACCGGAGCGCAGCGCCTGGGCCAGGGCCT GGGACCCTGCTCCGCCCCGCGCTCCCCTGCACCCCTTCCCCACGCTGCTCCCCTCTTCCTAAGCGGCCCCCCCTCTCCCGGGCAGCAGAA GAAGGGGTGGGACCCGGGCGGGCTCCGGGAGGGGGCCCTGGAGGAATGGATGGTGGCGGAAGGGCGGAGCAGGGGCGGGGCCCGCGGAGA CTCCACGGGGCGCCCCGGGCGTGAGGCACCCACTCTGGGAGCACAGAGAGCTCAGGTAGCCTGCCTAGATGGCGGCGCGCACCCTGGGCC GCGGCGTCGGGAGGCTGCTGGGCAGCCTGCGAGGGCTCTCGGGGCAGCCCGCGCGGCCGCCGTGCGGGGTGAGCGCGCCGCGCAGGGCGG CCTCGGGACCCTCGGGCAGCGCTCCCGCAGTTGCAGCAGCAGCAGCACAGCCAGGCTCGTATCCCGCGCTGAGTGCACAGGCAGCCCGGG AGCCGGCCGCCTTCTGGGGGCCTCTGGCGCGGGACACTCTCGTGTGGGACACCCCCTACCACACCGTCTGGGACTGCGACTTCAGCACTG GCAAGATCGGCTGGTTCCTGGGAGGCCAGTTAAATGTCTCTGTCAACTGCTTGGACCAGCATGTTCGGAAGTCCCCCGAGAGCGTTGCTT TGATCTGGGAGCGCGATGAGCCTGGAACGGAAGTGAGGATCACCTACAGGGAACTACTGGAGACCACGTGCCGCCTGGCCAACACGCTGA AGAGGCATGGAGTCCACCGTGGGGACCGTGTTGCCATCTACATGCCCGTGTCCCCATTGGCTGTGGCAGCAATGCTGGCCTGTGCCAGGA TCGGAGCTGTCCACACAGTCATCTTTGCTGGCTTCAGTGCAGAGTCCTTGGCTGGGAGGATCAATGATGCCAAGTGCAAGGTGGTTATCA CCTTCAACCAAGGACTCCGGGGTGGGCGCGTGGTGGAGCTGAAGAAAATAGTGGATGAGGCTGTGAAGCACTGCCCCACCGTGCAGCATG TCCTGGTGGCTCACAGGACAGACAACAAGGTCCACATGGGGGATCTGGACGTCCCGCTGGAGCAGGAAATGGCCAAGGAGGACCCTGTTT GCGCCCCAGAGAGCATGGGCAGTGAGGACATGCTCTTCATGCTGTACACCTCAGGGAGCACCGGAATGCCCAAGGGCATCGTCCATACCC AGGCAGGCTACCTGCTCTATGCCGCCCTGACTCACAAGCTTGTGTTTGACCACCAGCCAGGTGACATCTTTGGCTGTGTGGCCGACATCG GTTGGATTACAGGACACAGCTACGTGGTGTATGGGCCTCTCTGCAATGGTGCCACCAGCGTCCTTTTTGAGAGCACCCCAGTTTATCCCA ATGCTGGTCGGTACTGGGAGACAGTAGAGAGGTTGAAGATCAATCAGTTCTATGGCGCCCCAACGGCTGTCCGGCTGTTGCTGAAATACG GTGATGCCTGGGTGAAGAAGTATGATCGCTCCTCCCTGCGGACCCTGGGGTCAGCTGAAAACACTACTGAAAAGAAACGTGATGAGACCC GAGTTATGATCTTCTCTTCATTTCGAGATAGTGTTCAAGAAATTGCAGAAATGCTTTCACAGCATCAGCCAATTATTAGAGTAATGACTT TTGTCGGCCATGCCTCAGGGAAAAGCACGAAGGGTTTTACCCAGAAGGAGCAACTGGAGGTAGTGAAACAGTTTCGTGACGGTGGTTACA ACACGCTGGTTTCTACCTGTGTGGGTGAAGAAGGTTTGGATATAGGAGAAGTTGATCTTATAATATGTTTTGATTCCCAGAAGAGCCCAA TTCGTCTTGTACAACGAATGGGTAGAACTGGCCGTAAACGTCAAGGCAGGATAGTTATTATCCTTTCTGAAGGACGAGAGGAACGTATTT ATAATCAGAGTCAGTCCAACAAAAGAAGTATATATAAAGCTATTTCAAGTAACAGGCAGGTCCTTCATTTTTACCAAAGAAGTCCACGAA TGGTTCCTGATGGAATCAACCCAAAATTACACAAAATGTTCATCACACATGGTGTCTATGAACCAGAGAAGCCTTCTCGGAACTTGCAGC GAAAGTCATCTATCTTTTCCTATAGGGATGGTAAATAAATTTTGCATTTGACACATGCATTTTTCCCCTGTTCTTACTTAGCAGGTCGTA TCTTGATATAATATTTCTTGTTTGAAAAACTGAATATATGTTCTAATTAATATATTATAGGCATTCTCTTTGGAAAGGCTGTACGAGATT ATTCATGTGGCAAATGGAGAGACACTGGTAGTATAGAGTGACAGAAACTCAGTGTTGGGGAAAATTAAACATACCCTACCAACCCAGAGA >1536_1536_6_ACSS1-FANCM_ACSS1_chr20_25000646_ENST00000432802_FANCM_chr14_45628299_ENST00000556036_length(amino acids)=619AA_BP=415 MAARTLGRGVGRLLGSLRGLSGQPARPPCGVSAPRRAASGPSGSAPAVAAAAAQPGSYPALSAQAAREPAAFWGPLARDTLVWDTPYHTV WDCDFSTGKIGWFLGGQLNVSVNCLDQHVRKSPESVALIWERDEPGTEVRITYRELLETTCRLANTLKRHGVHRGDRVAIYMPVSPLAVA AMLACARIGAVHTVIFAGFSAESLAGRINDAKCKVVITFNQGLRGGRVVELKKIVDEAVKHCPTVQHVLVAHRTDNKVHMGDLDVPLEQE MAKEDPVCAPESMGSEDMLFMLYTSGSTGMPKGIVHTQAGYLLYAALTHKLVFDHQPGDIFGCVADIGWITGHSYVVYGPLCNGATSVLF ESTPVYPNAGRYWETVERLKINQFYGAPTAVRLLLKYGDAWVKKYDRSSLRTLGSAENTTEKKRDETRVMIFSSFRDSVQEIAEMLSQHQ PIIRVMTFVGHASGKSTKGFTQKEQLEVVKQFRDGGYNTLVSTCVGEEGLDIGEVDLIICFDSQKSPIRLVQRMGRTGRKRQGRIVIILS -------------------------------------------------------------- >1536_1536_7_ACSS1-FANCM_ACSS1_chr20_25000646_ENST00000537502_FANCM_chr14_45628299_ENST00000267430_length(transcript)=8159nt_BP=2529nt AGCTATGCAAACACGCTGCGAGCGGCCTTGAGAGCCCGAGGAGGGTCTGCTTTCTGGGCCCCTGCAGAGGGCAGGGGTCGCGGGCTGGTG GTCTGCCCCGCCCAGAGAGAAAGGGCCTTGGCTTCCCCTCATTCTTCGTTCTGTGTTAGCTCTTTTTATTGCAAATAATTAATTAAAGTC AGTACAGCAAGAGTGGGAAAGTGGTTAATGCAATTGCCAGGTCCAGATTCAGAGGGATGAGGCGCCGAAAGGAAAGACAACCTTGGGATC GCTTCCACTTCCTCCACTTCGCACCGCATGGCCGGCAAGTTGGCGGCTCTCGCCTGCTCCCAGTTTTCCCGGAGTTGAGTATGGTTGACT CTGACTGGACCAGGTTGGGTCACGTGTCGGCCCTGAGCCAATCAGCTTGCCCAGAGAGATGATGCGCCCTGAGTGGTGGGTGAACCTGGT GATAGGCCCCAGAGTGGCCAGAGAGGAAGGGCATGCGCACACCATAGACATAGGCAACGTGGTGGACGACATGGGGGCTGGGCGGGGGTG CTGCTCACCCACCTTGTGCCCAGTGCTTTCCCTTCCCCTTGTCCATGGTCCCCTAGCTTGGGGAGAAAGCAGGGTGCTTGCTCTACCCGC CAGTGCTGTCTCGGGGCTGCAGGGAGTTGTGGCTGCCCTGCTTGCGGTCTTCACTCCCAACTCACTGTGGCTTTGCAGAGCTGGAGTCCG CCCTATCTGGGCTTGGGGGTCTGCTCCCTGAGAGCATTATTTGGTGCCCCTCGACTGTGTTGATTCAGAAATCTGGGACCTGTTGTTTCT CGACTAAATGTCTTATGAGATCAGTCTTTCTTTTGGAGGCAAACATTTTCGGAAGTTTTGGAACCATGATGATCTATGCCTCAGACACTT GTGGTCCCTGAGAAGCTGCTGCTGGAAAAAGGGGTCCCCATCCGGATCCCAGGAGAGGGTTCTTGGATCATGCCGGGAAGGAATCCAAGG CGAGTGGCAGAGCGCAGTGAAAAGAGATAGTTTATTGAAAGCTTCTCAGTTACATAGTAGGGCATCCTCAGCAAGAGGAGGAATGCCTCT GTTTTGTTTCTTTCTTATATAGGGGTCTTATCTATGTAAAAGCTAAGCTATGTCTCCCTGCGGGTAGGCTGACGAAGTGACATTTATTAC TTTGTTGATTGAAAGAAAGCTATCCTTGGCATTTTAGTGCATAAGTACATCAAAGCATGCCTATAATCATCTTAAAAGCATATATTATGC AATATTGGGGCATCTGGACATTCTGTTGTTGCAAGAGTTTGTCTTTGCAGGTATTAAGCTACTTCGTCAGCTGTAAACATCTTATGACTG TGGGTCATGACTGGCAAGGAATGTGCCTTGCTAGTTTTAAGATGGAATTGATTCTAAAATGGTGTCACCATGGCTCCCCTACGCTCCTGT TCCCCTAAAAAAACCCTGCCGTAAGCGGACTTAAGGATAGCCTTGTCACCCTAGCAATGTGGCAGTGAATCTCTGCCAATAGCAATCTAC AAATGTTAAAAACTTTTCTTTTTCTGGAAAAGTACTTTCCATGCATTAAGTATTCAAGTGCCTGTTTTCCTGGCACTGGGCTGGATGTAT ATGACATAAAATTTGCAGTATTGCTCCACCCCCAAACTGCTCTGCATTTTGGCCCTCCTCCATCTCTGATGGCTTTCTCTTCCCTGTGCT GCAGGGAACTACTGGAGACCACGTGCCGCCTGGCCAACACGCTGAAGAGGCATGGAGTCCACCGTGGGGACCGTGTTGCCATCTACATGC CCGTGTCCCCATTGGCTGTGGCAGCAATGCTGGCCTGTGCCAGGATCGGAGCTGTCCACACAGTCATCTTTGCTGGCTTCAGTGCAGAGT CCTTGGCTGGGAGGATCAATGATGCCAAGTGCAAGGTGGTTATCACCTTCAACCAAGGACTCCGGGGTGGGCGCGTGGTGGAGCTGAAGA AAATAGTGGATGAGGCTGTGAAGCACTGCCCCACCGTGCAGCATGTCCTGGTGGCTCACAGGACAGACAACAAGGTCCACATGGGGGATC TGGACGTCCCGCTGGAGCAGGAAATGGCCAAGGAGGACCCTGTTTGCGCCCCAGAGAGCATGGGCAGTGAGGACATGCTCTTCATGCTGT ACACCTCAGGGAGCACCGGAATGCCCAAGGGCATCGTCCATACCCAGGCAGGCTACCTGCTCTATGCCGCCCTGACTCACAAGCTTGTGT TTGACCACCAGCCAGGTGACATCTTTGGCTGTGTGGCCGACATCGGTTGGATTACAGGACACAGCTACGTGGTGTATGGGCCTCTCTGCA ATGGTGCCACCAGCGTCCTTTTTGAGAGCACCCCAGTTTATCCCAATGCTGGTCGGTACTGGGAGACAGTAGAGAGGTTGAAGATCAATC AGTTCTATGGCGCCCCAACGGCTGTCCGGCTGTTGCTGAAATACGGTGATGCCTGGGTGAAGAAGTATGATCGCTCCTCCCTGCGGACCC TGGGGTCAGCTGAAAACACTACTGAAAAGAAACGTGATGAGACCCGAGTTATGATCTTCTCTTCATTTCGAGATAGTGTTCAAGAAATTG CAGAAATGCTTTCACAGCATCAGCCAATTATTAGAGTAATGACTTTTGTCGGCCATGCCTCAGGGAAAAGCACGAAGGGTTTTACCCAGA AGGAGCAACTGGAGGTAGTGAAACAGTTTCGTGACGGTGGTTACAACACGCTGGTTTCTACCTGTGTGGGTGAAGAAGGTTTGGATATAG GAGAAGTTGATCTTATAATATGTTTTGATTCCCAGAAGAGCCCAATTCGTCTTGTACAACGAATGGGTAGAACTGGCCGTAAACGTCAAG GCAGGATAGTTATTATCCTTTCTGAAGGACGAGAGGAACGTATTTATAATCAGAGTCAGTCCAACAAAAGAAGTATATATAAAGCTATTT CAAGTAACAGGCAGGTCCTTCATTTTTACCAAAGAAGTCCACGAATGGTTCCTGATGGAATCAACCCAAAATTACACAAAATGTTCATCA CACATGGTGTCTATGAACCAGAGAAGCCTTCTCGGAACTTGCAGCGAAAGTCATCTATCTTTTCCTATAGGGATGGAATGAGGCAAAGTA GCCTAAAGAAAGATTGGTTCTTATCAGAAGAAGAATTTAAATTATGGAACAGACTTTATAGATTAAGGGACAGTGATGAAATTAAAGAGA TAACATTGCCTCAAGTTCAGTTTTCTTCTTTACAAAATGAGGAAAACAAACCAGCTCAAGAATCAACCACTGGAATTCATCAACTCTCTC TCTCTGAATGGAGACTGTGGCAAGATCATCCTTTGCCTACACATCAAGTTGATCACTCAGATCGATGCCGCCATTTTATAGGCCTTATGC AAATGATAGAGGGAATGAGACACGAAGAGGGAGAATGCAGCTATGAATTGGAAGTTGAATCTTATTTACAAATGGAAGATGTTACCTCAA CATTTATTGCTCCCAGGAATGAATCTAATAATCTTGCCAGTGACACCTTTATCACTCACAAGAAATCGTCATTTATAAAGAACATAAATC AAGGCAGTTCATCCTCAGTGATAGAATCTGATGAAGAATGTGCTGAAATTGTTAAACAAACTCATATCAAACCTACTAAAATTGTTTCTT TAAAGAAAAAAGTGTCTAAAGAAATAAAAAAAGATCAGCTTAAAAAAGAAAATAATCACGGTATTATAGATTCTGTAGATAATGACAGAA ATTCCACTGTTGAAAATATTTTTCAAGAAGACCTACCAAATGATAAAAGGACATCAGATACAGATGAAATTGCTGCCACATGTACTATTA ATGAAAATGTTATTAAAGAACCGTGTGTGTTATTAACAGAGTGTCAGTTTACAAATAAATCCACTAGTTCACTTGCTGGAAATGTTTTAG ATTCTGGTTATAACAGTTTCAATGATGAAAAATCTGTTTCATCTAACTTATTTCTTCCATTCGAAGAAGAGCTTTATATTGTTAGAACAG ATGACCAATTTTATAATTGTCACTCATTGACAAAAGAGGTACTAGCTAATGTAGAGAGATTTTTATCTTATTCTCCTCCGCCTCTCAGTG GACTCTCAGACTTGGAATATGAAATTGCTAAGGGTACTGCACTTGAGAATTTGCTTTTCTTACCCTGTGCAGAGCATTTACGAAGTGATA AATGCACCTGTTTGCTGTCACATTCAGCTGTGAATTCTCAACAGAATTTAGAATTGAATTCACTTAAATGTATAAATTATCCATCTGAAA AAAGTTGCCTTTATGATATACCTAATGATAATATTTCTGATGAGCCAAGTCTCTGTGACTGTGATGTACATAAACATAATCAAAATGAAA ATTTAGTACCTAACAATCGTGTTCAAATACACAGAAGCCCTGCACAGAATTTAGTTGGAGAGAACAATCATGATGTTGATAACAGTGACC TCCCAGTATTGTCCACTGATCAAGATGAAAGTTTGCTGTTATTTGAAGATGTTAATACAGAGTTCGACGATGTGAGTCTTTCACCCTTGA ACAGTAAAAGCGAATCTTTACCTGTGTCAGACAAAACTGCTATTAGTGAAACGCCTCTGGTCTCTCAGTTCTTAATTTCTGATGAACTTT TGTTGGACAATAATTCTGAACTCCAAGATCAAATCACCCGTGATGCTAATAGTTTTAAATCTCGTGATCAGAGAGGTGTACAGGAAGAAA AAGTGAAGAATCATGAGGATATTTTTGATTGCTCTAGGGATTTATTTTCTGTTACCTTTGATTTAGGATTCTGTAGTCCAGATTCTGATG ATGAAATATTGGAACATACATCAGATAGCAATAGACCTCTAGATGATCTATATGGAAGGTATTTGGAAATTAAGGAGATAAGTGATGCAA ATTATGTTTCGAATCAAGCACTAATACCAAGAGATCATAGTAAAAATTTTACTAGTGGAACTGTTATTATCCCATCAAATGAAGATATGC AGAATCCAAATTATGTACATTTGCCACTGAGTGCAGCAAAAAATGAAGAATTGTTATCTCCTGGTTATTCTCAGTTTTCTTTACCAGTGC AAAAAAAAGTTATGAGTACACCACTCTCTAAATCAAACACATTGAACTCATTTTCTAAGATAAGAAAGGAAATACTTAAGACACCAGATT CTAGTAAGGAAAAAGTAAACCTACAAAGATTCAAAGAAGCATTGAATTCAACTTTTGATTATTCAGAATTTTCTCTAGAAAAGTCTAAAA GCAGTGGTCCAATGTATCTGCATAAATCCTGTCATTCTGTTGAAGATGGACAATTATTAACAAGTAACGAAAGTGAAGATGACGAGATTT TCCGAAGAAAAGTTAAAAGAGCAAAAGGAAATGTTTTAAACTCTCCTGAGGATCAGAAAAATAGTGAAGTTGATTCTCCACTTCATGCTG TCAAAAAGCGCAGATTTCCTATAAACAGATCAGAATTATCATCTAGTGATGAGAGTGAGAATTTTCCCAAACCATGTTCACAATTAGAAG ACTTCAAGGTTTGTAACGGGAATGCCAGAAGAGGCATCAAAGTCCCAAAGAGACAGAGTCACTTAAAGCATGTAGCTAGGAAGTTTTTAG ATGATGAAGCAGAACTTTCTGAAGAAGATGCAGAATATGTTTCATCAGATGAAAATGATGAGTCAGAAAATGAACAAGATTCCTCATTAC TTGACTTTTTAAATGATGAAACTCAACTTTCACAGGCTATAAATGATTCTGAAATGAGAGCTATTTACATGAAATCTTTGCGTAGTCCAA TGATGAACAATAAGTACAAAATGATTCATAAGACACATAAAAACATAAACATTTTCTCGCAGATTCCTGAACAAGATGAAACCTATTTAG AGGATAGTTTTTGTGTTGATGAAGAGGAGTCTTGCAAAGGCCAATCAAGTGAAGAAGAAGTTTGTGTTGATTTTAACTTAATAACTGATG ATTGCTTTGCAAATAGTAAAAAGTATAAAACTCGACGTGCAGTAATGCTAAAAGAAATGATGGAACAAAATTGTGCACATTCAAAAAAGA AATTATCCAGAATTATTTTACCAGATGATTCAAGTGAGGAGGAGAACAATGTAAATGATAAAAGAGAATCTAATATTGCGGTTAACCCAA GCACTGTTAAGAAGAACAAACAACAGGACCATTGTTTAAATTCAGTGCCTTCTGGATCTTCTGCGCAGTCCAAGGTGCGTTCTACTCCAA GAGTTAATCCATTAGCAAAGCAGAGCAAACAGACATCGCTGAATTTAAAGGATACAATTTCCGAAGTCTCAGACTTCAAACCTCAGAATC ATAATGAAGTCCAGTCTACCACACCACCCTTCACTACTGTTGATTCACAGAAAGACTGTAGAAAATTTCCAGTTCCACAGAAGGATGGTA GTGCTTTGGAGGATTCTAGCACTTCAGGGGCATCCTGTTCCAAGTCAAGACCACATTTAGCTGGGACACATACTTCTCTTAGACTTCCGC AGGAAGGAAAAGGAACCTGTATTCTTGTAGGTGGTCATGAAATCACTTCTGGATTAGAAGTAATTTCTTCCCTAAGAGCAATTCATGGGT TGCAAGTAGAAGTTTGTCCTCTTAATGGCTGTGATTACATCGTGAGTAATCGCATGGTGGTGGAAAGGAGGTCTCAATCTGAGATGTTAA ATAGTGTCAATAAGAACAAGTTCATTGAGCAGATCCAGCACCTGCAGAGTATGTTTGAAAGAATATGTGTGATTGTGGAAAAGGACAGAG AAAAAACAGGAGACACATCAAGGATGTTTAGGAGAACAAAGAGCTATGACAGCCTGCTGACTACCTTAATTGGCGCTGGAATCCGAATTC TTTTCAGTTCCTGCCAAGAAGAAACCGCAGATTTGCTAAAGGAACTGTCTTTAGTGGAACAAAGAAAGAATGTTGGTATTCATGTTCCAA CAGTGGTGAATAGTAATAAAAGTGAGGCACTCCAGTTTTATTTAAGTATTCCCAATATAAGTTATATAACTGCATTAAATATGTGTCACC AGTTTTCATCTGTGAAAAGGATGGCTAACAGCTCACTTCAAGAAATCTCCATGTATGCACAAGTAACTCATCAGAAGGCTGAGGAGATCT ATAGATATATTCACTATGTATTTGACATACAAATGTTACCAAATGATCTTAACCAAGATAGACTGAAATCTGATATATAATCAAGCTGCT CAAGATGGGGTTTTCAAAGACCTCTCACAATATTAAATGCACTTCAATAATCATTGCTGTTTTATGTTTATTTGTAAATAAGAGAATATT TTATTTAAATATTTTATATTGTATACATTTTTATTTATAGATTATAGAAATTATTAAAAAAGAAAAATCTGATGTTCAGTGATCATTTTG ACTAGATTATAAAACTAATTTTTCTTATTAAATAAAACAAGGTTTATTAAAAGTGTTACTAAGGATAGTTTAAGAAAGTAAAAGCTAAGC TAGAGATATACTTTGGAATGTTTCCCAAAATTAAAGTTGTACTGTTGTGATAAATAGTAAAGTTGACATGTCTATGACTACAGCCAACTT GTCGATTTTCCCTATGTGTAGATAGTATACTTTTAAGTGTACTGATTCTAAATACATGTACTTGGTAAGGTGTGGGTGATGGGTGGGTTG TGAGATAAATGACCCAGTAACTAGGAAAGTAGAAAACTTAACTGAATGTTTATCTGACCAAAGGTGTGTCCCAGTTAAGTACTGTCAAAT CTATTAATATGAACTCTGATATGGTTTGGCTGTGTCCCCAACCAAAATCTCATCTTGACTTGTAATCTGAATTATAATCCCAATATATTG GGGAGGGACCTCCTGGAACGTGATTAGCTCATGGGGGCGGTTCCCCCATGCTGTTCTAGTGATAGTTCTCAGAGGATCTGATGGTTTTAT AAGCTTTTCCTCTGTTCACTCTGCAGTTCTCTTGCCTACTGCCATGTGGAAAAGGAAACGTTTGCTTCCCCTCCACCATGATTGTAAGTT >1536_1536_7_ACSS1-FANCM_ACSS1_chr20_25000646_ENST00000537502_FANCM_chr14_45628299_ENST00000267430_length(amino acids)=1915AA_BP=332 MLKTFLFLEKYFPCIKYSSACFPGTGLDVYDIKFAVLLHPQTALHFGPPPSLMAFSSLCCRELLETTCRLANTLKRHGVHRGDRVAIYMP VSPLAVAAMLACARIGAVHTVIFAGFSAESLAGRINDAKCKVVITFNQGLRGGRVVELKKIVDEAVKHCPTVQHVLVAHRTDNKVHMGDL DVPLEQEMAKEDPVCAPESMGSEDMLFMLYTSGSTGMPKGIVHTQAGYLLYAALTHKLVFDHQPGDIFGCVADIGWITGHSYVVYGPLCN GATSVLFESTPVYPNAGRYWETVERLKINQFYGAPTAVRLLLKYGDAWVKKYDRSSLRTLGSAENTTEKKRDETRVMIFSSFRDSVQEIA EMLSQHQPIIRVMTFVGHASGKSTKGFTQKEQLEVVKQFRDGGYNTLVSTCVGEEGLDIGEVDLIICFDSQKSPIRLVQRMGRTGRKRQG RIVIILSEGREERIYNQSQSNKRSIYKAISSNRQVLHFYQRSPRMVPDGINPKLHKMFITHGVYEPEKPSRNLQRKSSIFSYRDGMRQSS LKKDWFLSEEEFKLWNRLYRLRDSDEIKEITLPQVQFSSLQNEENKPAQESTTGIHQLSLSEWRLWQDHPLPTHQVDHSDRCRHFIGLMQ MIEGMRHEEGECSYELEVESYLQMEDVTSTFIAPRNESNNLASDTFITHKKSSFIKNINQGSSSSVIESDEECAEIVKQTHIKPTKIVSL KKKVSKEIKKDQLKKENNHGIIDSVDNDRNSTVENIFQEDLPNDKRTSDTDEIAATCTINENVIKEPCVLLTECQFTNKSTSSLAGNVLD SGYNSFNDEKSVSSNLFLPFEEELYIVRTDDQFYNCHSLTKEVLANVERFLSYSPPPLSGLSDLEYEIAKGTALENLLFLPCAEHLRSDK CTCLLSHSAVNSQQNLELNSLKCINYPSEKSCLYDIPNDNISDEPSLCDCDVHKHNQNENLVPNNRVQIHRSPAQNLVGENNHDVDNSDL PVLSTDQDESLLLFEDVNTEFDDVSLSPLNSKSESLPVSDKTAISETPLVSQFLISDELLLDNNSELQDQITRDANSFKSRDQRGVQEEK VKNHEDIFDCSRDLFSVTFDLGFCSPDSDDEILEHTSDSNRPLDDLYGRYLEIKEISDANYVSNQALIPRDHSKNFTSGTVIIPSNEDMQ NPNYVHLPLSAAKNEELLSPGYSQFSLPVQKKVMSTPLSKSNTLNSFSKIRKEILKTPDSSKEKVNLQRFKEALNSTFDYSEFSLEKSKS SGPMYLHKSCHSVEDGQLLTSNESEDDEIFRRKVKRAKGNVLNSPEDQKNSEVDSPLHAVKKRRFPINRSELSSSDESENFPKPCSQLED FKVCNGNARRGIKVPKRQSHLKHVARKFLDDEAELSEEDAEYVSSDENDESENEQDSSLLDFLNDETQLSQAINDSEMRAIYMKSLRSPM MNNKYKMIHKTHKNINIFSQIPEQDETYLEDSFCVDEEESCKGQSSEEEVCVDFNLITDDCFANSKKYKTRRAVMLKEMMEQNCAHSKKK LSRIILPDDSSEEENNVNDKRESNIAVNPSTVKKNKQQDHCLNSVPSGSSAQSKVRSTPRVNPLAKQSKQTSLNLKDTISEVSDFKPQNH NEVQSTTPPFTTVDSQKDCRKFPVPQKDGSALEDSSTSGASCSKSRPHLAGTHTSLRLPQEGKGTCILVGGHEITSGLEVISSLRAIHGL QVEVCPLNGCDYIVSNRMVVERRSQSEMLNSVNKNKFIEQIQHLQSMFERICVIVEKDREKTGDTSRMFRRTKSYDSLLTTLIGAGIRIL FSSCQEETADLLKELSLVEQRKNVGIHVPTVVNSNKSEALQFYLSIPNISYITALNMCHQFSSVKRMANSSLQEISMYAQVTHQKAEEIY -------------------------------------------------------------- >1536_1536_8_ACSS1-FANCM_ACSS1_chr20_25000646_ENST00000537502_FANCM_chr14_45628299_ENST00000542564_length(transcript)=7300nt_BP=2529nt AGCTATGCAAACACGCTGCGAGCGGCCTTGAGAGCCCGAGGAGGGTCTGCTTTCTGGGCCCCTGCAGAGGGCAGGGGTCGCGGGCTGGTG GTCTGCCCCGCCCAGAGAGAAAGGGCCTTGGCTTCCCCTCATTCTTCGTTCTGTGTTAGCTCTTTTTATTGCAAATAATTAATTAAAGTC AGTACAGCAAGAGTGGGAAAGTGGTTAATGCAATTGCCAGGTCCAGATTCAGAGGGATGAGGCGCCGAAAGGAAAGACAACCTTGGGATC GCTTCCACTTCCTCCACTTCGCACCGCATGGCCGGCAAGTTGGCGGCTCTCGCCTGCTCCCAGTTTTCCCGGAGTTGAGTATGGTTGACT CTGACTGGACCAGGTTGGGTCACGTGTCGGCCCTGAGCCAATCAGCTTGCCCAGAGAGATGATGCGCCCTGAGTGGTGGGTGAACCTGGT GATAGGCCCCAGAGTGGCCAGAGAGGAAGGGCATGCGCACACCATAGACATAGGCAACGTGGTGGACGACATGGGGGCTGGGCGGGGGTG CTGCTCACCCACCTTGTGCCCAGTGCTTTCCCTTCCCCTTGTCCATGGTCCCCTAGCTTGGGGAGAAAGCAGGGTGCTTGCTCTACCCGC CAGTGCTGTCTCGGGGCTGCAGGGAGTTGTGGCTGCCCTGCTTGCGGTCTTCACTCCCAACTCACTGTGGCTTTGCAGAGCTGGAGTCCG CCCTATCTGGGCTTGGGGGTCTGCTCCCTGAGAGCATTATTTGGTGCCCCTCGACTGTGTTGATTCAGAAATCTGGGACCTGTTGTTTCT CGACTAAATGTCTTATGAGATCAGTCTTTCTTTTGGAGGCAAACATTTTCGGAAGTTTTGGAACCATGATGATCTATGCCTCAGACACTT GTGGTCCCTGAGAAGCTGCTGCTGGAAAAAGGGGTCCCCATCCGGATCCCAGGAGAGGGTTCTTGGATCATGCCGGGAAGGAATCCAAGG CGAGTGGCAGAGCGCAGTGAAAAGAGATAGTTTATTGAAAGCTTCTCAGTTACATAGTAGGGCATCCTCAGCAAGAGGAGGAATGCCTCT GTTTTGTTTCTTTCTTATATAGGGGTCTTATCTATGTAAAAGCTAAGCTATGTCTCCCTGCGGGTAGGCTGACGAAGTGACATTTATTAC TTTGTTGATTGAAAGAAAGCTATCCTTGGCATTTTAGTGCATAAGTACATCAAAGCATGCCTATAATCATCTTAAAAGCATATATTATGC AATATTGGGGCATCTGGACATTCTGTTGTTGCAAGAGTTTGTCTTTGCAGGTATTAAGCTACTTCGTCAGCTGTAAACATCTTATGACTG TGGGTCATGACTGGCAAGGAATGTGCCTTGCTAGTTTTAAGATGGAATTGATTCTAAAATGGTGTCACCATGGCTCCCCTACGCTCCTGT TCCCCTAAAAAAACCCTGCCGTAAGCGGACTTAAGGATAGCCTTGTCACCCTAGCAATGTGGCAGTGAATCTCTGCCAATAGCAATCTAC AAATGTTAAAAACTTTTCTTTTTCTGGAAAAGTACTTTCCATGCATTAAGTATTCAAGTGCCTGTTTTCCTGGCACTGGGCTGGATGTAT ATGACATAAAATTTGCAGTATTGCTCCACCCCCAAACTGCTCTGCATTTTGGCCCTCCTCCATCTCTGATGGCTTTCTCTTCCCTGTGCT GCAGGGAACTACTGGAGACCACGTGCCGCCTGGCCAACACGCTGAAGAGGCATGGAGTCCACCGTGGGGACCGTGTTGCCATCTACATGC CCGTGTCCCCATTGGCTGTGGCAGCAATGCTGGCCTGTGCCAGGATCGGAGCTGTCCACACAGTCATCTTTGCTGGCTTCAGTGCAGAGT CCTTGGCTGGGAGGATCAATGATGCCAAGTGCAAGGTGGTTATCACCTTCAACCAAGGACTCCGGGGTGGGCGCGTGGTGGAGCTGAAGA AAATAGTGGATGAGGCTGTGAAGCACTGCCCCACCGTGCAGCATGTCCTGGTGGCTCACAGGACAGACAACAAGGTCCACATGGGGGATC TGGACGTCCCGCTGGAGCAGGAAATGGCCAAGGAGGACCCTGTTTGCGCCCCAGAGAGCATGGGCAGTGAGGACATGCTCTTCATGCTGT ACACCTCAGGGAGCACCGGAATGCCCAAGGGCATCGTCCATACCCAGGCAGGCTACCTGCTCTATGCCGCCCTGACTCACAAGCTTGTGT TTGACCACCAGCCAGGTGACATCTTTGGCTGTGTGGCCGACATCGGTTGGATTACAGGACACAGCTACGTGGTGTATGGGCCTCTCTGCA ATGGTGCCACCAGCGTCCTTTTTGAGAGCACCCCAGTTTATCCCAATGCTGGTCGGTACTGGGAGACAGTAGAGAGGTTGAAGATCAATC AGTTCTATGGCGCCCCAACGGCTGTCCGGCTGTTGCTGAAATACGGTGATGCCTGGGTGAAGAAGTATGATCGCTCCTCCCTGCGGACCC TGGGGTCAGCTGAAAACACTACTGAAAAGAAACGTGATGAGACCCGAGTTATGATCTTCTCTTCATTTCGAGATAGTGTTCAAGAAATTG CAGAAATGCTTTCACAGCATCAGCCAATTATTAGAGTAATGACTTTTGTCGGCCATGCCTCAGGGAAAAGCACGAAGGGTTTTACCCAGA AGGAGCAACTGGAGGTAGTGAAACAGTTTCGTGACGGTGGTTACAACACGCTGGTTTCTACCTGTGTGGGTGAAGAAGGTTTGGATATAG GAGAAGTTGATCTTATAATATGTTTTGATTCCCAGAAGAGCCCAATTCGTCTTGTACAACGAATGGGTAGAACTGGCCGTAAACGTCAAG GCAGGATAGTTATTATCCTTTCTGAAGGACGAGAGGAACGTATTTATAATCAGAGTCAGTCCAACAAAAGAAGTATATATAAAGCTATTT CAAGTAACAGGCAGGTCCTTCATTTTTACCAAAGAAGTCCACGAATGGTTCCTGATGGAATCAACCCAAAATTACACAAAATGTTCATCA CACATGGTGTCTATGAACCAGAGAAGCCTTCTCGGAACTTGCAGCGAAAGTCATCTATCTTTTCCTATAGGGATGGAATGAGGCAAAGTA GCCTAAAGAAAGATTGGTTCTTATCAGAAGAAGAATTTAAATTATGGAACAGACTTTATAGATTAAGGGACAGTGATGAAATTAAAGAGA TAACATTGCCTCAAGTTCAGTTTTCTTCTTTACAAAATGAGGAAAACAAACCAGCTCAAGAATCAACCACTGGAATTCATCAACTCTCTC TCTCTGAATGGAGACTGTGGCAAGATCATCCTTTGCCTACACATCAAGTTGATCACTCAGATCGATGCCGCCATTTTATAGGCCTTATGC AAATGATAGAGGGAATGAGACACGAAGAGGGAGAATGCAGCTATGAATTGGAAGTTGAATCTTATTTACAAATGGAAGATGTTACCTCAA CATTTATTGCTCCCAGGAATGAATCTAATAATCTTGCCAGTGACACCTTTATCACTCACAAGAAATCGTCATTTATAAAGAACATAAATC AAGGCAGTTCATCCTCAGTGATAGAATCTGATGAAGAATGTGCTGAAATTGTTAAACAAACTCATATCAAACCTACTAAAATTGTTTCTT TAAAGAAAAAAGTGTCTAAAGAAATAAAAAAAGATCAGCTTAAAAAAGAAAATAATCACGGTATTATAGATTCTGTAGATAATGACAGAA ATTCCACTGTTGAAAATATTTTTCAAGAAGACCTACCAAATGATAAAAGGACATCAGATACAGATGAAATTGCTGCCACATGTACTATTA ATGAAAATGTTATTAAAGAACCGTGTGTGTTATTAACAGAGTGTCAGTTTACAAATAAATCCACTAGTTCACTTGCTGGAAATGTTTTAG ATTCTGGTTATAACAGTTTCAATGATGAAAAATCTGTTTCATCTAACTTATTTCTTCCATTCGAAGAAGAGCTTTATATTGTTAGAACAG ATGACCAATTTTATAATTGTCACTCATTGACAAAAGAGGTACTAGCTAATGTAGAGAGATTTTTATCTTATTCTCCTCCGCCTCTCAGTG GACTCTCAGACTTGGAATATGAAATTGCTAAGGGTACTGCACTTGAGAATTTGCTTTTCTTACCCTGTGCAGAGCATTTACGAAGTGATA AATGCACCTGTTTGCTGTCACATTCAGCTGTGAATTCTCAACAGAATTTAGAATTGAATTCACTTAAATGTATAAATTATCCATCTGAAA AAAGTTGCCTTTATGATATACCTAATGATAATATTTCTGATGAGCCAAGTCTCTGTGACTGTGATGTACATAAACATAATCAAAATGAAA ATTTAGTACCTAACAATCGTGTTCAAATACACAGAAGCCCTGCACAGAATTTAGTTGGAGAGAACAATCATGATGTTGATAACAGTGACC TCCCAGTATTGTCCACTGATCAAGATGAAAGTTTGCTGTTATTTGAAGATGTTAATACAGAGTTCGACGATGTGAGTCTTTCACCCTTGA ACAGTAAAAGCGAATCTTTACCTGTGTCAGACAAAACTGCTATTAGTGAAACGCCTCTGGTCTCTCAGTTCTTAATTTCTGATGAACTTT TGTTGGACAATAATTCTGAACTCCAAGATCAAATCACCCGTGATGCTAATAGTTTTAAATCTCGTGATCAGAGAGGTGTACAGGAAGAAA AAGTGAAGAATCATGAGGATATTTTTGATTGCTCTAGGGATTTATTTTCTGTTACCTTTGATTTAGGATTCTGTAGTCCAGATTCTGATG ATGAAATATTGGAACATACATCAGATAGCAATAGACCTCTAGATGATCTATATGGAAGGTATTTGGAAATTAAGGAGATAAGTGATGCAA ATTATGTTTCGAATCAAGCACTAATACCAAGAGATCATAGTAAAAATTTTACTAGTGGAACTGTTATTATCCCATCAAATGAAGATATGC AGAATCCAAATTATGTACATTTGCCACTGAGTGCAGCAAAAAATGAAGAATTGTTATCTCCTGGTTATTCTCAGTTTTCTTTACCAGTGC AAAAAAAAGTTATGAGTACACCACTCTCTAAATCAAACACATTGAACTCATTTTCTAAGATAAGAAAGGAAATACTTAAGACACCAGATT CTAGTAAGGAAAAAGTAAACCTACAAAGATTCAAAGAAGCATTGAATTCAACTTTTGATTATTCAGAATTTTCTCTAGAAAAGTCTAAAA GCAGTGGTCCAATGTATCTGCATAAATCCTGTCATTCTGTTGAAGATGGACAATTATTAACAAGTAACGAAAGTGAAGATGACGAGATTT TCCGAAGAAAAGTTAAAAGAGCAAAAGGAAATGTTTTAAACTCTCCTGAGGATCAGAAAAATAGTGAAGTTGATTCTCCACTTCATGCTG TCAAAAAGCGCAGATTTCCTATAAACAGATCAGAATTATCATCTAGTGATGAGAGTGAGAATTTTCCCAAACCATGTTCACAATTAGAAG ACTTCAAGGTTTGTAACGGGAATGCCAGAAGAGGCATCAAAGTCCCAAAGAGACAGAGTCACTTAAAGCATGTAGCTAGGAAGTTTTTAG ATGATGAAGCAGAACTTTCTGAAGAAGATGCAGAATATGTTTCATCAGATGAAAATGATGAGTCAGAAAATGAACAAGATTCCTCATTAC TTGACTTTTTAAATGATGAAACTCAACTTTCACAGGCTATAAATGATTCTGAAATGAGAGCTATTTACATGAAATCTTTGCGTAGTCCAA TGATGAACAATAAGTACAAAATGATTCATAAGACACATAAAAACATAAACATTTTCTCGCAGATTCCTGAACAAGATGAAACCTATTTAG AGGATAGTTTTTGTGTTGATGAAGAGGAGTCTTGCAAAGGCCAATCAAGTGAAGAAGAAGTTTGTGTTGATTTTAACTTAATAACTGATG ATTGCTTTGCAAATAGTAAAAAGTATAAAACTCGACGTGCAGTAATGCTAAAAGAAATGATGGAACAAAATTGTGCACATTCAAAAAAGA AATTATCCAGAATTATTTTACCAGATGATTCAAGTGAGGAGGAGAACAATGTAAATGATAAAAGAGAATCTAATATTGCGGTTAACCCAA GCACTGTTAAGAAGAACAAACAACAGGACCATTGTTTAAATTCAGTGCCTTCTGGATCTTCTGCGCAGTCCAAGGTGCGTTCTACTCCAA GAGTTAATCCATTAGCAAAGCAGAGCAAACAGACATCGCTGAATTTAAAGGATACAATTTCCGAAGTCTCAGACTTCAAACCTCAGAATC ATAATGAAGTCCAGTCTACCACACCACCCTTCACTACTGTTGATTCACAGAAAGACTGTAGAAAATTTCCAGTTCCACAGAAGGATGGTA GTGCTTTGGAGGATTCTAGCACTTCAGGGGCATCCTGTTCCAAGTCAAGACCACATTTAGCTGGGACACATACTTCTCTTAGACTTCCGC AGGAAGGAAAAGGAACCTGTATTCTTGTAGGTGGTCATGAAATCACTTCTGGATTAGAAGTAATTTCTTCCCTAAGAGCAATTCATGGGT TGCAAGTAGAAGTTTGTCCTCTTAATGGCTGTGATTACATCGTGAGTAATCGCATGGTGGTGGAAAGGAGGTCTCAATCTGAGATGTTAA ATAGTGTCAATAAGAACAAGTTCATTGAGCAGATCCAGCACCTGCAGAGTATGTTTGAAAGAATATGTGTGATTGTGGAAAAGGACAGAG AAAAAACAGGAGACACATCAAGGATGTTTAGGAGAACAAAGAGCTATGACAGCCTGCTGACTACCTTAATTGGCGCTGGAATCCGAATTC TTTTCAGTTCCTGCCAAGAAGAAACCGCAGATTTGCTAAAGGAACTGTCTTTAGTGGAACAAAGAAAGAATGTTGGTATTCATGTTCCAA CAGTGGTGAATAGTAATAAAAGTGAGGCACTCCAGTTTTATTTAAGTATTCCCAATATAAGTTATATAACTGCATTAAATATGTGTCACC AGTTTTCATCTGTGAAAAGGATGGCTAACAGCTCACTTCAAGAAATCTCCATGTATGCACAAGTAACTCATCAGAAGGCTGAGGAGATCT ATAGATATATTCACTATGTATTTGACATACAAATGTTACCAAATGATCTTAACCAAGATAGACTGAAATCTGATATATAATCAAGCTGCT >1536_1536_8_ACSS1-FANCM_ACSS1_chr20_25000646_ENST00000537502_FANCM_chr14_45628299_ENST00000542564_length(amino acids)=1915AA_BP=332 MLKTFLFLEKYFPCIKYSSACFPGTGLDVYDIKFAVLLHPQTALHFGPPPSLMAFSSLCCRELLETTCRLANTLKRHGVHRGDRVAIYMP VSPLAVAAMLACARIGAVHTVIFAGFSAESLAGRINDAKCKVVITFNQGLRGGRVVELKKIVDEAVKHCPTVQHVLVAHRTDNKVHMGDL DVPLEQEMAKEDPVCAPESMGSEDMLFMLYTSGSTGMPKGIVHTQAGYLLYAALTHKLVFDHQPGDIFGCVADIGWITGHSYVVYGPLCN GATSVLFESTPVYPNAGRYWETVERLKINQFYGAPTAVRLLLKYGDAWVKKYDRSSLRTLGSAENTTEKKRDETRVMIFSSFRDSVQEIA EMLSQHQPIIRVMTFVGHASGKSTKGFTQKEQLEVVKQFRDGGYNTLVSTCVGEEGLDIGEVDLIICFDSQKSPIRLVQRMGRTGRKRQG RIVIILSEGREERIYNQSQSNKRSIYKAISSNRQVLHFYQRSPRMVPDGINPKLHKMFITHGVYEPEKPSRNLQRKSSIFSYRDGMRQSS LKKDWFLSEEEFKLWNRLYRLRDSDEIKEITLPQVQFSSLQNEENKPAQESTTGIHQLSLSEWRLWQDHPLPTHQVDHSDRCRHFIGLMQ MIEGMRHEEGECSYELEVESYLQMEDVTSTFIAPRNESNNLASDTFITHKKSSFIKNINQGSSSSVIESDEECAEIVKQTHIKPTKIVSL KKKVSKEIKKDQLKKENNHGIIDSVDNDRNSTVENIFQEDLPNDKRTSDTDEIAATCTINENVIKEPCVLLTECQFTNKSTSSLAGNVLD SGYNSFNDEKSVSSNLFLPFEEELYIVRTDDQFYNCHSLTKEVLANVERFLSYSPPPLSGLSDLEYEIAKGTALENLLFLPCAEHLRSDK CTCLLSHSAVNSQQNLELNSLKCINYPSEKSCLYDIPNDNISDEPSLCDCDVHKHNQNENLVPNNRVQIHRSPAQNLVGENNHDVDNSDL PVLSTDQDESLLLFEDVNTEFDDVSLSPLNSKSESLPVSDKTAISETPLVSQFLISDELLLDNNSELQDQITRDANSFKSRDQRGVQEEK VKNHEDIFDCSRDLFSVTFDLGFCSPDSDDEILEHTSDSNRPLDDLYGRYLEIKEISDANYVSNQALIPRDHSKNFTSGTVIIPSNEDMQ NPNYVHLPLSAAKNEELLSPGYSQFSLPVQKKVMSTPLSKSNTLNSFSKIRKEILKTPDSSKEKVNLQRFKEALNSTFDYSEFSLEKSKS SGPMYLHKSCHSVEDGQLLTSNESEDDEIFRRKVKRAKGNVLNSPEDQKNSEVDSPLHAVKKRRFPINRSELSSSDESENFPKPCSQLED FKVCNGNARRGIKVPKRQSHLKHVARKFLDDEAELSEEDAEYVSSDENDESENEQDSSLLDFLNDETQLSQAINDSEMRAIYMKSLRSPM MNNKYKMIHKTHKNINIFSQIPEQDETYLEDSFCVDEEESCKGQSSEEEVCVDFNLITDDCFANSKKYKTRRAVMLKEMMEQNCAHSKKK LSRIILPDDSSEEENNVNDKRESNIAVNPSTVKKNKQQDHCLNSVPSGSSAQSKVRSTPRVNPLAKQSKQTSLNLKDTISEVSDFKPQNH NEVQSTTPPFTTVDSQKDCRKFPVPQKDGSALEDSSTSGASCSKSRPHLAGTHTSLRLPQEGKGTCILVGGHEITSGLEVISSLRAIHGL QVEVCPLNGCDYIVSNRMVVERRSQSEMLNSVNKNKFIEQIQHLQSMFERICVIVEKDREKTGDTSRMFRRTKSYDSLLTTLIGAGIRIL FSSCQEETADLLKELSLVEQRKNVGIHVPTVVNSNKSEALQFYLSIPNISYITALNMCHQFSSVKRMANSSLQEISMYAQVTHQKAEEIY -------------------------------------------------------------- >1536_1536_9_ACSS1-FANCM_ACSS1_chr20_25000646_ENST00000537502_FANCM_chr14_45628299_ENST00000556036_length(transcript)=3395nt_BP=2529nt AGCTATGCAAACACGCTGCGAGCGGCCTTGAGAGCCCGAGGAGGGTCTGCTTTCTGGGCCCCTGCAGAGGGCAGGGGTCGCGGGCTGGTG GTCTGCCCCGCCCAGAGAGAAAGGGCCTTGGCTTCCCCTCATTCTTCGTTCTGTGTTAGCTCTTTTTATTGCAAATAATTAATTAAAGTC AGTACAGCAAGAGTGGGAAAGTGGTTAATGCAATTGCCAGGTCCAGATTCAGAGGGATGAGGCGCCGAAAGGAAAGACAACCTTGGGATC GCTTCCACTTCCTCCACTTCGCACCGCATGGCCGGCAAGTTGGCGGCTCTCGCCTGCTCCCAGTTTTCCCGGAGTTGAGTATGGTTGACT CTGACTGGACCAGGTTGGGTCACGTGTCGGCCCTGAGCCAATCAGCTTGCCCAGAGAGATGATGCGCCCTGAGTGGTGGGTGAACCTGGT GATAGGCCCCAGAGTGGCCAGAGAGGAAGGGCATGCGCACACCATAGACATAGGCAACGTGGTGGACGACATGGGGGCTGGGCGGGGGTG CTGCTCACCCACCTTGTGCCCAGTGCTTTCCCTTCCCCTTGTCCATGGTCCCCTAGCTTGGGGAGAAAGCAGGGTGCTTGCTCTACCCGC CAGTGCTGTCTCGGGGCTGCAGGGAGTTGTGGCTGCCCTGCTTGCGGTCTTCACTCCCAACTCACTGTGGCTTTGCAGAGCTGGAGTCCG CCCTATCTGGGCTTGGGGGTCTGCTCCCTGAGAGCATTATTTGGTGCCCCTCGACTGTGTTGATTCAGAAATCTGGGACCTGTTGTTTCT CGACTAAATGTCTTATGAGATCAGTCTTTCTTTTGGAGGCAAACATTTTCGGAAGTTTTGGAACCATGATGATCTATGCCTCAGACACTT GTGGTCCCTGAGAAGCTGCTGCTGGAAAAAGGGGTCCCCATCCGGATCCCAGGAGAGGGTTCTTGGATCATGCCGGGAAGGAATCCAAGG CGAGTGGCAGAGCGCAGTGAAAAGAGATAGTTTATTGAAAGCTTCTCAGTTACATAGTAGGGCATCCTCAGCAAGAGGAGGAATGCCTCT GTTTTGTTTCTTTCTTATATAGGGGTCTTATCTATGTAAAAGCTAAGCTATGTCTCCCTGCGGGTAGGCTGACGAAGTGACATTTATTAC TTTGTTGATTGAAAGAAAGCTATCCTTGGCATTTTAGTGCATAAGTACATCAAAGCATGCCTATAATCATCTTAAAAGCATATATTATGC AATATTGGGGCATCTGGACATTCTGTTGTTGCAAGAGTTTGTCTTTGCAGGTATTAAGCTACTTCGTCAGCTGTAAACATCTTATGACTG TGGGTCATGACTGGCAAGGAATGTGCCTTGCTAGTTTTAAGATGGAATTGATTCTAAAATGGTGTCACCATGGCTCCCCTACGCTCCTGT TCCCCTAAAAAAACCCTGCCGTAAGCGGACTTAAGGATAGCCTTGTCACCCTAGCAATGTGGCAGTGAATCTCTGCCAATAGCAATCTAC AAATGTTAAAAACTTTTCTTTTTCTGGAAAAGTACTTTCCATGCATTAAGTATTCAAGTGCCTGTTTTCCTGGCACTGGGCTGGATGTAT ATGACATAAAATTTGCAGTATTGCTCCACCCCCAAACTGCTCTGCATTTTGGCCCTCCTCCATCTCTGATGGCTTTCTCTTCCCTGTGCT GCAGGGAACTACTGGAGACCACGTGCCGCCTGGCCAACACGCTGAAGAGGCATGGAGTCCACCGTGGGGACCGTGTTGCCATCTACATGC CCGTGTCCCCATTGGCTGTGGCAGCAATGCTGGCCTGTGCCAGGATCGGAGCTGTCCACACAGTCATCTTTGCTGGCTTCAGTGCAGAGT CCTTGGCTGGGAGGATCAATGATGCCAAGTGCAAGGTGGTTATCACCTTCAACCAAGGACTCCGGGGTGGGCGCGTGGTGGAGCTGAAGA AAATAGTGGATGAGGCTGTGAAGCACTGCCCCACCGTGCAGCATGTCCTGGTGGCTCACAGGACAGACAACAAGGTCCACATGGGGGATC TGGACGTCCCGCTGGAGCAGGAAATGGCCAAGGAGGACCCTGTTTGCGCCCCAGAGAGCATGGGCAGTGAGGACATGCTCTTCATGCTGT ACACCTCAGGGAGCACCGGAATGCCCAAGGGCATCGTCCATACCCAGGCAGGCTACCTGCTCTATGCCGCCCTGACTCACAAGCTTGTGT TTGACCACCAGCCAGGTGACATCTTTGGCTGTGTGGCCGACATCGGTTGGATTACAGGACACAGCTACGTGGTGTATGGGCCTCTCTGCA ATGGTGCCACCAGCGTCCTTTTTGAGAGCACCCCAGTTTATCCCAATGCTGGTCGGTACTGGGAGACAGTAGAGAGGTTGAAGATCAATC AGTTCTATGGCGCCCCAACGGCTGTCCGGCTGTTGCTGAAATACGGTGATGCCTGGGTGAAGAAGTATGATCGCTCCTCCCTGCGGACCC TGGGGTCAGCTGAAAACACTACTGAAAAGAAACGTGATGAGACCCGAGTTATGATCTTCTCTTCATTTCGAGATAGTGTTCAAGAAATTG CAGAAATGCTTTCACAGCATCAGCCAATTATTAGAGTAATGACTTTTGTCGGCCATGCCTCAGGGAAAAGCACGAAGGGTTTTACCCAGA AGGAGCAACTGGAGGTAGTGAAACAGTTTCGTGACGGTGGTTACAACACGCTGGTTTCTACCTGTGTGGGTGAAGAAGGTTTGGATATAG GAGAAGTTGATCTTATAATATGTTTTGATTCCCAGAAGAGCCCAATTCGTCTTGTACAACGAATGGGTAGAACTGGCCGTAAACGTCAAG GCAGGATAGTTATTATCCTTTCTGAAGGACGAGAGGAACGTATTTATAATCAGAGTCAGTCCAACAAAAGAAGTATATATAAAGCTATTT CAAGTAACAGGCAGGTCCTTCATTTTTACCAAAGAAGTCCACGAATGGTTCCTGATGGAATCAACCCAAAATTACACAAAATGTTCATCA CACATGGTGTCTATGAACCAGAGAAGCCTTCTCGGAACTTGCAGCGAAAGTCATCTATCTTTTCCTATAGGGATGGTAAATAAATTTTGC ATTTGACACATGCATTTTTCCCCTGTTCTTACTTAGCAGGTCGTATCTTGATATAATATTTCTTGTTTGAAAAACTGAATATATGTTCTA ATTAATATATTATAGGCATTCTCTTTGGAAAGGCTGTACGAGATTATTCATGTGGCAAATGGAGAGACACTGGTAGTATAGAGTGACAGA >1536_1536_9_ACSS1-FANCM_ACSS1_chr20_25000646_ENST00000537502_FANCM_chr14_45628299_ENST00000556036_length(amino acids)=536AA_BP=332 MLKTFLFLEKYFPCIKYSSACFPGTGLDVYDIKFAVLLHPQTALHFGPPPSLMAFSSLCCRELLETTCRLANTLKRHGVHRGDRVAIYMP VSPLAVAAMLACARIGAVHTVIFAGFSAESLAGRINDAKCKVVITFNQGLRGGRVVELKKIVDEAVKHCPTVQHVLVAHRTDNKVHMGDL DVPLEQEMAKEDPVCAPESMGSEDMLFMLYTSGSTGMPKGIVHTQAGYLLYAALTHKLVFDHQPGDIFGCVADIGWITGHSYVVYGPLCN GATSVLFESTPVYPNAGRYWETVERLKINQFYGAPTAVRLLLKYGDAWVKKYDRSSLRTLGSAENTTEKKRDETRVMIFSSFRDSVQEIA EMLSQHQPIIRVMTFVGHASGKSTKGFTQKEQLEVVKQFRDGGYNTLVSTCVGEEGLDIGEVDLIICFDSQKSPIRLVQRMGRTGRKRQG -------------------------------------------------------------- >1536_1536_10_ACSS1-FANCM_ACSS1_chr20_25000646_ENST00000542618_FANCM_chr14_45628299_ENST00000267430_length(transcript)=6780nt_BP=1150nt CCTTTCCTTGACTACCCTTTGAACAGAGGAGAGCTATGCAAACACGCTGCGAGCGGCCTTGAGAGCCCGAGGAGGGTCTGCTTTCTGGGC CCCTGCAGAGGGCAGGGGTCGCGGGCTGGTGGTCTGCCCCGCCCAGAGAGAAAGGGCCTTGGCTTCCCCTCATTCTTCGTTCTGTGTTAG CTCTTTTTATTGCAAATAATTAATTAAAGTCAGTACAGCAAGAGTGGGAAAGTGGTTAATGCAATTGCCAGGTCCAGATTCAGAGGGATG AGGCGCCGAAAGGAAAGACAACCTTGGGATCGCTTCCACTTCCTCCACTTCGCACCGCATGGCCGGGAACTACTGGAGACCACGTGCCGC CTGGCCAACACGCTGAAGAGGCATGGAGTCCACCGTGGGGACCGTGTTGCCATCTACATGCCCGTGTCCCCATTGGCTGTGGCAGCAATG CTGGCCTGTGCCAGGATCGGAGCTGTCCACACAGTCATCTTTGCTGGCTTCAGTGCAGAGTCCTTGGCTGGGAGGATCAATGATGCCAAG TGCAAGGTGGTTATCACCTTCAACCAAGGACTCCGGGGTGGGCGCGTGGTGGAGCTGAAGAAAATAGTGGATGAGGCTGTGAAGCACTGC CCCACCGTGCAGCATGTCCTGGTGGCTCACAGGACAGACAACAAGGTCCACATGGGGGATCTGGACGTCCCGCTGGAGCAGGAAATGGCC AAGGAGGACCCTGTTTGCGCCCCAGAGAGCATGGGCAGTGAGGACATGCTCTTCATGCTGTACACCTCAGGGAGCACCGGAATGCCCAAG GGCATCGTCCATACCCAGGCAGGCTACCTGCTCTATGCCGCCCTGACTCACAAGCTTGTGTTTGACCACCAGCCAGGTGACATCTTTGGC TGTGTGGCCGACATCGGTTGGATTACAGGACACAGCTACGTGGTGTATGGGCCTCTCTGCAATGGTGCCACCAGCGTCCTTTTTGAGAGC ACCCCAGTTTATCCCAATGCTGGTCGGTACTGGGAGACAGTAGAGAGGTTGAAGATCAATCAGTTCTATGGCGCCCCAACGGCTGTCCGG CTGTTGCTGAAATACGGTGATGCCTGGGTGAAGAAGTATGATCGCTCCTCCCTGCGGACCCTGGGGTCAGCTGAAAACACTACTGAAAAG AAACGTGATGAGACCCGAGTTATGATCTTCTCTTCATTTCGAGATAGTGTTCAAGAAATTGCAGAAATGCTTTCACAGCATCAGCCAATT ATTAGAGTAATGACTTTTGTCGGCCATGCCTCAGGGAAAAGCACGAAGGGTTTTACCCAGAAGGAGCAACTGGAGGTAGTGAAACAGTTT CGTGACGGTGGTTACAACACGCTGGTTTCTACCTGTGTGGGTGAAGAAGGTTTGGATATAGGAGAAGTTGATCTTATAATATGTTTTGAT TCCCAGAAGAGCCCAATTCGTCTTGTACAACGAATGGGTAGAACTGGCCGTAAACGTCAAGGCAGGATAGTTATTATCCTTTCTGAAGGA CGAGAGGAACGTATTTATAATCAGAGTCAGTCCAACAAAAGAAGTATATATAAAGCTATTTCAAGTAACAGGCAGGTCCTTCATTTTTAC CAAAGAAGTCCACGAATGGTTCCTGATGGAATCAACCCAAAATTACACAAAATGTTCATCACACATGGTGTCTATGAACCAGAGAAGCCT TCTCGGAACTTGCAGCGAAAGTCATCTATCTTTTCCTATAGGGATGGAATGAGGCAAAGTAGCCTAAAGAAAGATTGGTTCTTATCAGAA GAAGAATTTAAATTATGGAACAGACTTTATAGATTAAGGGACAGTGATGAAATTAAAGAGATAACATTGCCTCAAGTTCAGTTTTCTTCT TTACAAAATGAGGAAAACAAACCAGCTCAAGAATCAACCACTGGAATTCATCAACTCTCTCTCTCTGAATGGAGACTGTGGCAAGATCAT CCTTTGCCTACACATCAAGTTGATCACTCAGATCGATGCCGCCATTTTATAGGCCTTATGCAAATGATAGAGGGAATGAGACACGAAGAG GGAGAATGCAGCTATGAATTGGAAGTTGAATCTTATTTACAAATGGAAGATGTTACCTCAACATTTATTGCTCCCAGGAATGAATCTAAT AATCTTGCCAGTGACACCTTTATCACTCACAAGAAATCGTCATTTATAAAGAACATAAATCAAGGCAGTTCATCCTCAGTGATAGAATCT GATGAAGAATGTGCTGAAATTGTTAAACAAACTCATATCAAACCTACTAAAATTGTTTCTTTAAAGAAAAAAGTGTCTAAAGAAATAAAA AAAGATCAGCTTAAAAAAGAAAATAATCACGGTATTATAGATTCTGTAGATAATGACAGAAATTCCACTGTTGAAAATATTTTTCAAGAA GACCTACCAAATGATAAAAGGACATCAGATACAGATGAAATTGCTGCCACATGTACTATTAATGAAAATGTTATTAAAGAACCGTGTGTG TTATTAACAGAGTGTCAGTTTACAAATAAATCCACTAGTTCACTTGCTGGAAATGTTTTAGATTCTGGTTATAACAGTTTCAATGATGAA AAATCTGTTTCATCTAACTTATTTCTTCCATTCGAAGAAGAGCTTTATATTGTTAGAACAGATGACCAATTTTATAATTGTCACTCATTG ACAAAAGAGGTACTAGCTAATGTAGAGAGATTTTTATCTTATTCTCCTCCGCCTCTCAGTGGACTCTCAGACTTGGAATATGAAATTGCT AAGGGTACTGCACTTGAGAATTTGCTTTTCTTACCCTGTGCAGAGCATTTACGAAGTGATAAATGCACCTGTTTGCTGTCACATTCAGCT GTGAATTCTCAACAGAATTTAGAATTGAATTCACTTAAATGTATAAATTATCCATCTGAAAAAAGTTGCCTTTATGATATACCTAATGAT AATATTTCTGATGAGCCAAGTCTCTGTGACTGTGATGTACATAAACATAATCAAAATGAAAATTTAGTACCTAACAATCGTGTTCAAATA CACAGAAGCCCTGCACAGAATTTAGTTGGAGAGAACAATCATGATGTTGATAACAGTGACCTCCCAGTATTGTCCACTGATCAAGATGAA AGTTTGCTGTTATTTGAAGATGTTAATACAGAGTTCGACGATGTGAGTCTTTCACCCTTGAACAGTAAAAGCGAATCTTTACCTGTGTCA GACAAAACTGCTATTAGTGAAACGCCTCTGGTCTCTCAGTTCTTAATTTCTGATGAACTTTTGTTGGACAATAATTCTGAACTCCAAGAT CAAATCACCCGTGATGCTAATAGTTTTAAATCTCGTGATCAGAGAGGTGTACAGGAAGAAAAAGTGAAGAATCATGAGGATATTTTTGAT TGCTCTAGGGATTTATTTTCTGTTACCTTTGATTTAGGATTCTGTAGTCCAGATTCTGATGATGAAATATTGGAACATACATCAGATAGC AATAGACCTCTAGATGATCTATATGGAAGGTATTTGGAAATTAAGGAGATAAGTGATGCAAATTATGTTTCGAATCAAGCACTAATACCA AGAGATCATAGTAAAAATTTTACTAGTGGAACTGTTATTATCCCATCAAATGAAGATATGCAGAATCCAAATTATGTACATTTGCCACTG AGTGCAGCAAAAAATGAAGAATTGTTATCTCCTGGTTATTCTCAGTTTTCTTTACCAGTGCAAAAAAAAGTTATGAGTACACCACTCTCT AAATCAAACACATTGAACTCATTTTCTAAGATAAGAAAGGAAATACTTAAGACACCAGATTCTAGTAAGGAAAAAGTAAACCTACAAAGA TTCAAAGAAGCATTGAATTCAACTTTTGATTATTCAGAATTTTCTCTAGAAAAGTCTAAAAGCAGTGGTCCAATGTATCTGCATAAATCC TGTCATTCTGTTGAAGATGGACAATTATTAACAAGTAACGAAAGTGAAGATGACGAGATTTTCCGAAGAAAAGTTAAAAGAGCAAAAGGA AATGTTTTAAACTCTCCTGAGGATCAGAAAAATAGTGAAGTTGATTCTCCACTTCATGCTGTCAAAAAGCGCAGATTTCCTATAAACAGA TCAGAATTATCATCTAGTGATGAGAGTGAGAATTTTCCCAAACCATGTTCACAATTAGAAGACTTCAAGGTTTGTAACGGGAATGCCAGA AGAGGCATCAAAGTCCCAAAGAGACAGAGTCACTTAAAGCATGTAGCTAGGAAGTTTTTAGATGATGAAGCAGAACTTTCTGAAGAAGAT GCAGAATATGTTTCATCAGATGAAAATGATGAGTCAGAAAATGAACAAGATTCCTCATTACTTGACTTTTTAAATGATGAAACTCAACTT TCACAGGCTATAAATGATTCTGAAATGAGAGCTATTTACATGAAATCTTTGCGTAGTCCAATGATGAACAATAAGTACAAAATGATTCAT AAGACACATAAAAACATAAACATTTTCTCGCAGATTCCTGAACAAGATGAAACCTATTTAGAGGATAGTTTTTGTGTTGATGAAGAGGAG TCTTGCAAAGGCCAATCAAGTGAAGAAGAAGTTTGTGTTGATTTTAACTTAATAACTGATGATTGCTTTGCAAATAGTAAAAAGTATAAA ACTCGACGTGCAGTAATGCTAAAAGAAATGATGGAACAAAATTGTGCACATTCAAAAAAGAAATTATCCAGAATTATTTTACCAGATGAT TCAAGTGAGGAGGAGAACAATGTAAATGATAAAAGAGAATCTAATATTGCGGTTAACCCAAGCACTGTTAAGAAGAACAAACAACAGGAC CATTGTTTAAATTCAGTGCCTTCTGGATCTTCTGCGCAGTCCAAGGTGCGTTCTACTCCAAGAGTTAATCCATTAGCAAAGCAGAGCAAA CAGACATCGCTGAATTTAAAGGATACAATTTCCGAAGTCTCAGACTTCAAACCTCAGAATCATAATGAAGTCCAGTCTACCACACCACCC TTCACTACTGTTGATTCACAGAAAGACTGTAGAAAATTTCCAGTTCCACAGAAGGATGGTAGTGCTTTGGAGGATTCTAGCACTTCAGGG GCATCCTGTTCCAAGTCAAGACCACATTTAGCTGGGACACATACTTCTCTTAGACTTCCGCAGGAAGGAAAAGGAACCTGTATTCTTGTA GGTGGTCATGAAATCACTTCTGGATTAGAAGTAATTTCTTCCCTAAGAGCAATTCATGGGTTGCAAGTAGAAGTTTGTCCTCTTAATGGC TGTGATTACATCGTGAGTAATCGCATGGTGGTGGAAAGGAGGTCTCAATCTGAGATGTTAAATAGTGTCAATAAGAACAAGTTCATTGAG CAGATCCAGCACCTGCAGAGTATGTTTGAAAGAATATGTGTGATTGTGGAAAAGGACAGAGAAAAAACAGGAGACACATCAAGGATGTTT AGGAGAACAAAGAGCTATGACAGCCTGCTGACTACCTTAATTGGCGCTGGAATCCGAATTCTTTTCAGTTCCTGCCAAGAAGAAACCGCA GATTTGCTAAAGGAACTGTCTTTAGTGGAACAAAGAAAGAATGTTGGTATTCATGTTCCAACAGTGGTGAATAGTAATAAAAGTGAGGCA CTCCAGTTTTATTTAAGTATTCCCAATATAAGTTATATAACTGCATTAAATATGTGTCACCAGTTTTCATCTGTGAAAAGGATGGCTAAC AGCTCACTTCAAGAAATCTCCATGTATGCACAAGTAACTCATCAGAAGGCTGAGGAGATCTATAGATATATTCACTATGTATTTGACATA CAAATGTTACCAAATGATCTTAACCAAGATAGACTGAAATCTGATATATAATCAAGCTGCTCAAGATGGGGTTTTCAAAGACCTCTCACA ATATTAAATGCACTTCAATAATCATTGCTGTTTTATGTTTATTTGTAAATAAGAGAATATTTTATTTAAATATTTTATATTGTATACATT TTTATTTATAGATTATAGAAATTATTAAAAAAGAAAAATCTGATGTTCAGTGATCATTTTGACTAGATTATAAAACTAATTTTTCTTATT AAATAAAACAAGGTTTATTAAAAGTGTTACTAAGGATAGTTTAAGAAAGTAAAAGCTAAGCTAGAGATATACTTTGGAATGTTTCCCAAA ATTAAAGTTGTACTGTTGTGATAAATAGTAAAGTTGACATGTCTATGACTACAGCCAACTTGTCGATTTTCCCTATGTGTAGATAGTATA CTTTTAAGTGTACTGATTCTAAATACATGTACTTGGTAAGGTGTGGGTGATGGGTGGGTTGTGAGATAAATGACCCAGTAACTAGGAAAG TAGAAAACTTAACTGAATGTTTATCTGACCAAAGGTGTGTCCCAGTTAAGTACTGTCAAATCTATTAATATGAACTCTGATATGGTTTGG CTGTGTCCCCAACCAAAATCTCATCTTGACTTGTAATCTGAATTATAATCCCAATATATTGGGGAGGGACCTCCTGGAACGTGATTAGCT CATGGGGGCGGTTCCCCCATGCTGTTCTAGTGATAGTTCTCAGAGGATCTGATGGTTTTATAAGCTTTTCCTCTGTTCACTCTGCAGTTC TCTTGCCTACTGCCATGTGGAAAAGGAAACGTTTGCTTCCCCTCCACCATGATTGTAAGTTCCCGAGGCCTCCCCAGCCATGCAGGACTG >1536_1536_10_ACSS1-FANCM_ACSS1_chr20_25000646_ENST00000542618_FANCM_chr14_45628299_ENST00000267430_length(amino acids)=1877AA_BP=294 MRRRKERQPWDRFHFLHFAPHGRELLETTCRLANTLKRHGVHRGDRVAIYMPVSPLAVAAMLACARIGAVHTVIFAGFSAESLAGRINDA KCKVVITFNQGLRGGRVVELKKIVDEAVKHCPTVQHVLVAHRTDNKVHMGDLDVPLEQEMAKEDPVCAPESMGSEDMLFMLYTSGSTGMP KGIVHTQAGYLLYAALTHKLVFDHQPGDIFGCVADIGWITGHSYVVYGPLCNGATSVLFESTPVYPNAGRYWETVERLKINQFYGAPTAV RLLLKYGDAWVKKYDRSSLRTLGSAENTTEKKRDETRVMIFSSFRDSVQEIAEMLSQHQPIIRVMTFVGHASGKSTKGFTQKEQLEVVKQ FRDGGYNTLVSTCVGEEGLDIGEVDLIICFDSQKSPIRLVQRMGRTGRKRQGRIVIILSEGREERIYNQSQSNKRSIYKAISSNRQVLHF YQRSPRMVPDGINPKLHKMFITHGVYEPEKPSRNLQRKSSIFSYRDGMRQSSLKKDWFLSEEEFKLWNRLYRLRDSDEIKEITLPQVQFS SLQNEENKPAQESTTGIHQLSLSEWRLWQDHPLPTHQVDHSDRCRHFIGLMQMIEGMRHEEGECSYELEVESYLQMEDVTSTFIAPRNES NNLASDTFITHKKSSFIKNINQGSSSSVIESDEECAEIVKQTHIKPTKIVSLKKKVSKEIKKDQLKKENNHGIIDSVDNDRNSTVENIFQ EDLPNDKRTSDTDEIAATCTINENVIKEPCVLLTECQFTNKSTSSLAGNVLDSGYNSFNDEKSVSSNLFLPFEEELYIVRTDDQFYNCHS LTKEVLANVERFLSYSPPPLSGLSDLEYEIAKGTALENLLFLPCAEHLRSDKCTCLLSHSAVNSQQNLELNSLKCINYPSEKSCLYDIPN DNISDEPSLCDCDVHKHNQNENLVPNNRVQIHRSPAQNLVGENNHDVDNSDLPVLSTDQDESLLLFEDVNTEFDDVSLSPLNSKSESLPV SDKTAISETPLVSQFLISDELLLDNNSELQDQITRDANSFKSRDQRGVQEEKVKNHEDIFDCSRDLFSVTFDLGFCSPDSDDEILEHTSD SNRPLDDLYGRYLEIKEISDANYVSNQALIPRDHSKNFTSGTVIIPSNEDMQNPNYVHLPLSAAKNEELLSPGYSQFSLPVQKKVMSTPL SKSNTLNSFSKIRKEILKTPDSSKEKVNLQRFKEALNSTFDYSEFSLEKSKSSGPMYLHKSCHSVEDGQLLTSNESEDDEIFRRKVKRAK GNVLNSPEDQKNSEVDSPLHAVKKRRFPINRSELSSSDESENFPKPCSQLEDFKVCNGNARRGIKVPKRQSHLKHVARKFLDDEAELSEE DAEYVSSDENDESENEQDSSLLDFLNDETQLSQAINDSEMRAIYMKSLRSPMMNNKYKMIHKTHKNINIFSQIPEQDETYLEDSFCVDEE ESCKGQSSEEEVCVDFNLITDDCFANSKKYKTRRAVMLKEMMEQNCAHSKKKLSRIILPDDSSEEENNVNDKRESNIAVNPSTVKKNKQQ DHCLNSVPSGSSAQSKVRSTPRVNPLAKQSKQTSLNLKDTISEVSDFKPQNHNEVQSTTPPFTTVDSQKDCRKFPVPQKDGSALEDSSTS GASCSKSRPHLAGTHTSLRLPQEGKGTCILVGGHEITSGLEVISSLRAIHGLQVEVCPLNGCDYIVSNRMVVERRSQSEMLNSVNKNKFI EQIQHLQSMFERICVIVEKDREKTGDTSRMFRRTKSYDSLLTTLIGAGIRILFSSCQEETADLLKELSLVEQRKNVGIHVPTVVNSNKSE -------------------------------------------------------------- >1536_1536_11_ACSS1-FANCM_ACSS1_chr20_25000646_ENST00000542618_FANCM_chr14_45628299_ENST00000542564_length(transcript)=5921nt_BP=1150nt CCTTTCCTTGACTACCCTTTGAACAGAGGAGAGCTATGCAAACACGCTGCGAGCGGCCTTGAGAGCCCGAGGAGGGTCTGCTTTCTGGGC CCCTGCAGAGGGCAGGGGTCGCGGGCTGGTGGTCTGCCCCGCCCAGAGAGAAAGGGCCTTGGCTTCCCCTCATTCTTCGTTCTGTGTTAG CTCTTTTTATTGCAAATAATTAATTAAAGTCAGTACAGCAAGAGTGGGAAAGTGGTTAATGCAATTGCCAGGTCCAGATTCAGAGGGATG AGGCGCCGAAAGGAAAGACAACCTTGGGATCGCTTCCACTTCCTCCACTTCGCACCGCATGGCCGGGAACTACTGGAGACCACGTGCCGC CTGGCCAACACGCTGAAGAGGCATGGAGTCCACCGTGGGGACCGTGTTGCCATCTACATGCCCGTGTCCCCATTGGCTGTGGCAGCAATG CTGGCCTGTGCCAGGATCGGAGCTGTCCACACAGTCATCTTTGCTGGCTTCAGTGCAGAGTCCTTGGCTGGGAGGATCAATGATGCCAAG TGCAAGGTGGTTATCACCTTCAACCAAGGACTCCGGGGTGGGCGCGTGGTGGAGCTGAAGAAAATAGTGGATGAGGCTGTGAAGCACTGC CCCACCGTGCAGCATGTCCTGGTGGCTCACAGGACAGACAACAAGGTCCACATGGGGGATCTGGACGTCCCGCTGGAGCAGGAAATGGCC AAGGAGGACCCTGTTTGCGCCCCAGAGAGCATGGGCAGTGAGGACATGCTCTTCATGCTGTACACCTCAGGGAGCACCGGAATGCCCAAG GGCATCGTCCATACCCAGGCAGGCTACCTGCTCTATGCCGCCCTGACTCACAAGCTTGTGTTTGACCACCAGCCAGGTGACATCTTTGGC TGTGTGGCCGACATCGGTTGGATTACAGGACACAGCTACGTGGTGTATGGGCCTCTCTGCAATGGTGCCACCAGCGTCCTTTTTGAGAGC ACCCCAGTTTATCCCAATGCTGGTCGGTACTGGGAGACAGTAGAGAGGTTGAAGATCAATCAGTTCTATGGCGCCCCAACGGCTGTCCGG CTGTTGCTGAAATACGGTGATGCCTGGGTGAAGAAGTATGATCGCTCCTCCCTGCGGACCCTGGGGTCAGCTGAAAACACTACTGAAAAG AAACGTGATGAGACCCGAGTTATGATCTTCTCTTCATTTCGAGATAGTGTTCAAGAAATTGCAGAAATGCTTTCACAGCATCAGCCAATT ATTAGAGTAATGACTTTTGTCGGCCATGCCTCAGGGAAAAGCACGAAGGGTTTTACCCAGAAGGAGCAACTGGAGGTAGTGAAACAGTTT CGTGACGGTGGTTACAACACGCTGGTTTCTACCTGTGTGGGTGAAGAAGGTTTGGATATAGGAGAAGTTGATCTTATAATATGTTTTGAT TCCCAGAAGAGCCCAATTCGTCTTGTACAACGAATGGGTAGAACTGGCCGTAAACGTCAAGGCAGGATAGTTATTATCCTTTCTGAAGGA CGAGAGGAACGTATTTATAATCAGAGTCAGTCCAACAAAAGAAGTATATATAAAGCTATTTCAAGTAACAGGCAGGTCCTTCATTTTTAC CAAAGAAGTCCACGAATGGTTCCTGATGGAATCAACCCAAAATTACACAAAATGTTCATCACACATGGTGTCTATGAACCAGAGAAGCCT TCTCGGAACTTGCAGCGAAAGTCATCTATCTTTTCCTATAGGGATGGAATGAGGCAAAGTAGCCTAAAGAAAGATTGGTTCTTATCAGAA GAAGAATTTAAATTATGGAACAGACTTTATAGATTAAGGGACAGTGATGAAATTAAAGAGATAACATTGCCTCAAGTTCAGTTTTCTTCT TTACAAAATGAGGAAAACAAACCAGCTCAAGAATCAACCACTGGAATTCATCAACTCTCTCTCTCTGAATGGAGACTGTGGCAAGATCAT CCTTTGCCTACACATCAAGTTGATCACTCAGATCGATGCCGCCATTTTATAGGCCTTATGCAAATGATAGAGGGAATGAGACACGAAGAG GGAGAATGCAGCTATGAATTGGAAGTTGAATCTTATTTACAAATGGAAGATGTTACCTCAACATTTATTGCTCCCAGGAATGAATCTAAT AATCTTGCCAGTGACACCTTTATCACTCACAAGAAATCGTCATTTATAAAGAACATAAATCAAGGCAGTTCATCCTCAGTGATAGAATCT GATGAAGAATGTGCTGAAATTGTTAAACAAACTCATATCAAACCTACTAAAATTGTTTCTTTAAAGAAAAAAGTGTCTAAAGAAATAAAA AAAGATCAGCTTAAAAAAGAAAATAATCACGGTATTATAGATTCTGTAGATAATGACAGAAATTCCACTGTTGAAAATATTTTTCAAGAA GACCTACCAAATGATAAAAGGACATCAGATACAGATGAAATTGCTGCCACATGTACTATTAATGAAAATGTTATTAAAGAACCGTGTGTG TTATTAACAGAGTGTCAGTTTACAAATAAATCCACTAGTTCACTTGCTGGAAATGTTTTAGATTCTGGTTATAACAGTTTCAATGATGAA AAATCTGTTTCATCTAACTTATTTCTTCCATTCGAAGAAGAGCTTTATATTGTTAGAACAGATGACCAATTTTATAATTGTCACTCATTG ACAAAAGAGGTACTAGCTAATGTAGAGAGATTTTTATCTTATTCTCCTCCGCCTCTCAGTGGACTCTCAGACTTGGAATATGAAATTGCT AAGGGTACTGCACTTGAGAATTTGCTTTTCTTACCCTGTGCAGAGCATTTACGAAGTGATAAATGCACCTGTTTGCTGTCACATTCAGCT GTGAATTCTCAACAGAATTTAGAATTGAATTCACTTAAATGTATAAATTATCCATCTGAAAAAAGTTGCCTTTATGATATACCTAATGAT AATATTTCTGATGAGCCAAGTCTCTGTGACTGTGATGTACATAAACATAATCAAAATGAAAATTTAGTACCTAACAATCGTGTTCAAATA CACAGAAGCCCTGCACAGAATTTAGTTGGAGAGAACAATCATGATGTTGATAACAGTGACCTCCCAGTATTGTCCACTGATCAAGATGAA AGTTTGCTGTTATTTGAAGATGTTAATACAGAGTTCGACGATGTGAGTCTTTCACCCTTGAACAGTAAAAGCGAATCTTTACCTGTGTCA GACAAAACTGCTATTAGTGAAACGCCTCTGGTCTCTCAGTTCTTAATTTCTGATGAACTTTTGTTGGACAATAATTCTGAACTCCAAGAT CAAATCACCCGTGATGCTAATAGTTTTAAATCTCGTGATCAGAGAGGTGTACAGGAAGAAAAAGTGAAGAATCATGAGGATATTTTTGAT TGCTCTAGGGATTTATTTTCTGTTACCTTTGATTTAGGATTCTGTAGTCCAGATTCTGATGATGAAATATTGGAACATACATCAGATAGC AATAGACCTCTAGATGATCTATATGGAAGGTATTTGGAAATTAAGGAGATAAGTGATGCAAATTATGTTTCGAATCAAGCACTAATACCA AGAGATCATAGTAAAAATTTTACTAGTGGAACTGTTATTATCCCATCAAATGAAGATATGCAGAATCCAAATTATGTACATTTGCCACTG AGTGCAGCAAAAAATGAAGAATTGTTATCTCCTGGTTATTCTCAGTTTTCTTTACCAGTGCAAAAAAAAGTTATGAGTACACCACTCTCT AAATCAAACACATTGAACTCATTTTCTAAGATAAGAAAGGAAATACTTAAGACACCAGATTCTAGTAAGGAAAAAGTAAACCTACAAAGA TTCAAAGAAGCATTGAATTCAACTTTTGATTATTCAGAATTTTCTCTAGAAAAGTCTAAAAGCAGTGGTCCAATGTATCTGCATAAATCC TGTCATTCTGTTGAAGATGGACAATTATTAACAAGTAACGAAAGTGAAGATGACGAGATTTTCCGAAGAAAAGTTAAAAGAGCAAAAGGA AATGTTTTAAACTCTCCTGAGGATCAGAAAAATAGTGAAGTTGATTCTCCACTTCATGCTGTCAAAAAGCGCAGATTTCCTATAAACAGA TCAGAATTATCATCTAGTGATGAGAGTGAGAATTTTCCCAAACCATGTTCACAATTAGAAGACTTCAAGGTTTGTAACGGGAATGCCAGA AGAGGCATCAAAGTCCCAAAGAGACAGAGTCACTTAAAGCATGTAGCTAGGAAGTTTTTAGATGATGAAGCAGAACTTTCTGAAGAAGAT GCAGAATATGTTTCATCAGATGAAAATGATGAGTCAGAAAATGAACAAGATTCCTCATTACTTGACTTTTTAAATGATGAAACTCAACTT TCACAGGCTATAAATGATTCTGAAATGAGAGCTATTTACATGAAATCTTTGCGTAGTCCAATGATGAACAATAAGTACAAAATGATTCAT AAGACACATAAAAACATAAACATTTTCTCGCAGATTCCTGAACAAGATGAAACCTATTTAGAGGATAGTTTTTGTGTTGATGAAGAGGAG TCTTGCAAAGGCCAATCAAGTGAAGAAGAAGTTTGTGTTGATTTTAACTTAATAACTGATGATTGCTTTGCAAATAGTAAAAAGTATAAA ACTCGACGTGCAGTAATGCTAAAAGAAATGATGGAACAAAATTGTGCACATTCAAAAAAGAAATTATCCAGAATTATTTTACCAGATGAT TCAAGTGAGGAGGAGAACAATGTAAATGATAAAAGAGAATCTAATATTGCGGTTAACCCAAGCACTGTTAAGAAGAACAAACAACAGGAC CATTGTTTAAATTCAGTGCCTTCTGGATCTTCTGCGCAGTCCAAGGTGCGTTCTACTCCAAGAGTTAATCCATTAGCAAAGCAGAGCAAA CAGACATCGCTGAATTTAAAGGATACAATTTCCGAAGTCTCAGACTTCAAACCTCAGAATCATAATGAAGTCCAGTCTACCACACCACCC TTCACTACTGTTGATTCACAGAAAGACTGTAGAAAATTTCCAGTTCCACAGAAGGATGGTAGTGCTTTGGAGGATTCTAGCACTTCAGGG GCATCCTGTTCCAAGTCAAGACCACATTTAGCTGGGACACATACTTCTCTTAGACTTCCGCAGGAAGGAAAAGGAACCTGTATTCTTGTA GGTGGTCATGAAATCACTTCTGGATTAGAAGTAATTTCTTCCCTAAGAGCAATTCATGGGTTGCAAGTAGAAGTTTGTCCTCTTAATGGC TGTGATTACATCGTGAGTAATCGCATGGTGGTGGAAAGGAGGTCTCAATCTGAGATGTTAAATAGTGTCAATAAGAACAAGTTCATTGAG CAGATCCAGCACCTGCAGAGTATGTTTGAAAGAATATGTGTGATTGTGGAAAAGGACAGAGAAAAAACAGGAGACACATCAAGGATGTTT AGGAGAACAAAGAGCTATGACAGCCTGCTGACTACCTTAATTGGCGCTGGAATCCGAATTCTTTTCAGTTCCTGCCAAGAAGAAACCGCA GATTTGCTAAAGGAACTGTCTTTAGTGGAACAAAGAAAGAATGTTGGTATTCATGTTCCAACAGTGGTGAATAGTAATAAAAGTGAGGCA CTCCAGTTTTATTTAAGTATTCCCAATATAAGTTATATAACTGCATTAAATATGTGTCACCAGTTTTCATCTGTGAAAAGGATGGCTAAC AGCTCACTTCAAGAAATCTCCATGTATGCACAAGTAACTCATCAGAAGGCTGAGGAGATCTATAGATATATTCACTATGTATTTGACATA >1536_1536_11_ACSS1-FANCM_ACSS1_chr20_25000646_ENST00000542618_FANCM_chr14_45628299_ENST00000542564_length(amino acids)=1877AA_BP=294 MRRRKERQPWDRFHFLHFAPHGRELLETTCRLANTLKRHGVHRGDRVAIYMPVSPLAVAAMLACARIGAVHTVIFAGFSAESLAGRINDA KCKVVITFNQGLRGGRVVELKKIVDEAVKHCPTVQHVLVAHRTDNKVHMGDLDVPLEQEMAKEDPVCAPESMGSEDMLFMLYTSGSTGMP KGIVHTQAGYLLYAALTHKLVFDHQPGDIFGCVADIGWITGHSYVVYGPLCNGATSVLFESTPVYPNAGRYWETVERLKINQFYGAPTAV RLLLKYGDAWVKKYDRSSLRTLGSAENTTEKKRDETRVMIFSSFRDSVQEIAEMLSQHQPIIRVMTFVGHASGKSTKGFTQKEQLEVVKQ FRDGGYNTLVSTCVGEEGLDIGEVDLIICFDSQKSPIRLVQRMGRTGRKRQGRIVIILSEGREERIYNQSQSNKRSIYKAISSNRQVLHF YQRSPRMVPDGINPKLHKMFITHGVYEPEKPSRNLQRKSSIFSYRDGMRQSSLKKDWFLSEEEFKLWNRLYRLRDSDEIKEITLPQVQFS SLQNEENKPAQESTTGIHQLSLSEWRLWQDHPLPTHQVDHSDRCRHFIGLMQMIEGMRHEEGECSYELEVESYLQMEDVTSTFIAPRNES NNLASDTFITHKKSSFIKNINQGSSSSVIESDEECAEIVKQTHIKPTKIVSLKKKVSKEIKKDQLKKENNHGIIDSVDNDRNSTVENIFQ EDLPNDKRTSDTDEIAATCTINENVIKEPCVLLTECQFTNKSTSSLAGNVLDSGYNSFNDEKSVSSNLFLPFEEELYIVRTDDQFYNCHS LTKEVLANVERFLSYSPPPLSGLSDLEYEIAKGTALENLLFLPCAEHLRSDKCTCLLSHSAVNSQQNLELNSLKCINYPSEKSCLYDIPN DNISDEPSLCDCDVHKHNQNENLVPNNRVQIHRSPAQNLVGENNHDVDNSDLPVLSTDQDESLLLFEDVNTEFDDVSLSPLNSKSESLPV SDKTAISETPLVSQFLISDELLLDNNSELQDQITRDANSFKSRDQRGVQEEKVKNHEDIFDCSRDLFSVTFDLGFCSPDSDDEILEHTSD SNRPLDDLYGRYLEIKEISDANYVSNQALIPRDHSKNFTSGTVIIPSNEDMQNPNYVHLPLSAAKNEELLSPGYSQFSLPVQKKVMSTPL SKSNTLNSFSKIRKEILKTPDSSKEKVNLQRFKEALNSTFDYSEFSLEKSKSSGPMYLHKSCHSVEDGQLLTSNESEDDEIFRRKVKRAK GNVLNSPEDQKNSEVDSPLHAVKKRRFPINRSELSSSDESENFPKPCSQLEDFKVCNGNARRGIKVPKRQSHLKHVARKFLDDEAELSEE DAEYVSSDENDESENEQDSSLLDFLNDETQLSQAINDSEMRAIYMKSLRSPMMNNKYKMIHKTHKNINIFSQIPEQDETYLEDSFCVDEE ESCKGQSSEEEVCVDFNLITDDCFANSKKYKTRRAVMLKEMMEQNCAHSKKKLSRIILPDDSSEEENNVNDKRESNIAVNPSTVKKNKQQ DHCLNSVPSGSSAQSKVRSTPRVNPLAKQSKQTSLNLKDTISEVSDFKPQNHNEVQSTTPPFTTVDSQKDCRKFPVPQKDGSALEDSSTS GASCSKSRPHLAGTHTSLRLPQEGKGTCILVGGHEITSGLEVISSLRAIHGLQVEVCPLNGCDYIVSNRMVVERRSQSEMLNSVNKNKFI EQIQHLQSMFERICVIVEKDREKTGDTSRMFRRTKSYDSLLTTLIGAGIRILFSSCQEETADLLKELSLVEQRKNVGIHVPTVVNSNKSE -------------------------------------------------------------- >1536_1536_12_ACSS1-FANCM_ACSS1_chr20_25000646_ENST00000542618_FANCM_chr14_45628299_ENST00000556036_length(transcript)=2016nt_BP=1150nt CCTTTCCTTGACTACCCTTTGAACAGAGGAGAGCTATGCAAACACGCTGCGAGCGGCCTTGAGAGCCCGAGGAGGGTCTGCTTTCTGGGC CCCTGCAGAGGGCAGGGGTCGCGGGCTGGTGGTCTGCCCCGCCCAGAGAGAAAGGGCCTTGGCTTCCCCTCATTCTTCGTTCTGTGTTAG CTCTTTTTATTGCAAATAATTAATTAAAGTCAGTACAGCAAGAGTGGGAAAGTGGTTAATGCAATTGCCAGGTCCAGATTCAGAGGGATG AGGCGCCGAAAGGAAAGACAACCTTGGGATCGCTTCCACTTCCTCCACTTCGCACCGCATGGCCGGGAACTACTGGAGACCACGTGCCGC CTGGCCAACACGCTGAAGAGGCATGGAGTCCACCGTGGGGACCGTGTTGCCATCTACATGCCCGTGTCCCCATTGGCTGTGGCAGCAATG CTGGCCTGTGCCAGGATCGGAGCTGTCCACACAGTCATCTTTGCTGGCTTCAGTGCAGAGTCCTTGGCTGGGAGGATCAATGATGCCAAG TGCAAGGTGGTTATCACCTTCAACCAAGGACTCCGGGGTGGGCGCGTGGTGGAGCTGAAGAAAATAGTGGATGAGGCTGTGAAGCACTGC CCCACCGTGCAGCATGTCCTGGTGGCTCACAGGACAGACAACAAGGTCCACATGGGGGATCTGGACGTCCCGCTGGAGCAGGAAATGGCC AAGGAGGACCCTGTTTGCGCCCCAGAGAGCATGGGCAGTGAGGACATGCTCTTCATGCTGTACACCTCAGGGAGCACCGGAATGCCCAAG GGCATCGTCCATACCCAGGCAGGCTACCTGCTCTATGCCGCCCTGACTCACAAGCTTGTGTTTGACCACCAGCCAGGTGACATCTTTGGC TGTGTGGCCGACATCGGTTGGATTACAGGACACAGCTACGTGGTGTATGGGCCTCTCTGCAATGGTGCCACCAGCGTCCTTTTTGAGAGC ACCCCAGTTTATCCCAATGCTGGTCGGTACTGGGAGACAGTAGAGAGGTTGAAGATCAATCAGTTCTATGGCGCCCCAACGGCTGTCCGG CTGTTGCTGAAATACGGTGATGCCTGGGTGAAGAAGTATGATCGCTCCTCCCTGCGGACCCTGGGGTCAGCTGAAAACACTACTGAAAAG AAACGTGATGAGACCCGAGTTATGATCTTCTCTTCATTTCGAGATAGTGTTCAAGAAATTGCAGAAATGCTTTCACAGCATCAGCCAATT ATTAGAGTAATGACTTTTGTCGGCCATGCCTCAGGGAAAAGCACGAAGGGTTTTACCCAGAAGGAGCAACTGGAGGTAGTGAAACAGTTT CGTGACGGTGGTTACAACACGCTGGTTTCTACCTGTGTGGGTGAAGAAGGTTTGGATATAGGAGAAGTTGATCTTATAATATGTTTTGAT TCCCAGAAGAGCCCAATTCGTCTTGTACAACGAATGGGTAGAACTGGCCGTAAACGTCAAGGCAGGATAGTTATTATCCTTTCTGAAGGA CGAGAGGAACGTATTTATAATCAGAGTCAGTCCAACAAAAGAAGTATATATAAAGCTATTTCAAGTAACAGGCAGGTCCTTCATTTTTAC CAAAGAAGTCCACGAATGGTTCCTGATGGAATCAACCCAAAATTACACAAAATGTTCATCACACATGGTGTCTATGAACCAGAGAAGCCT TCTCGGAACTTGCAGCGAAAGTCATCTATCTTTTCCTATAGGGATGGTAAATAAATTTTGCATTTGACACATGCATTTTTCCCCTGTTCT TACTTAGCAGGTCGTATCTTGATATAATATTTCTTGTTTGAAAAACTGAATATATGTTCTAATTAATATATTATAGGCATTCTCTTTGGA AAGGCTGTACGAGATTATTCATGTGGCAAATGGAGAGACACTGGTAGTATAGAGTGACAGAAACTCAGTGTTGGGGAAAATTAAACATAC >1536_1536_12_ACSS1-FANCM_ACSS1_chr20_25000646_ENST00000542618_FANCM_chr14_45628299_ENST00000556036_length(amino acids)=498AA_BP=294 MRRRKERQPWDRFHFLHFAPHGRELLETTCRLANTLKRHGVHRGDRVAIYMPVSPLAVAAMLACARIGAVHTVIFAGFSAESLAGRINDA KCKVVITFNQGLRGGRVVELKKIVDEAVKHCPTVQHVLVAHRTDNKVHMGDLDVPLEQEMAKEDPVCAPESMGSEDMLFMLYTSGSTGMP KGIVHTQAGYLLYAALTHKLVFDHQPGDIFGCVADIGWITGHSYVVYGPLCNGATSVLFESTPVYPNAGRYWETVERLKINQFYGAPTAV RLLLKYGDAWVKKYDRSSLRTLGSAENTTEKKRDETRVMIFSSFRDSVQEIAEMLSQHQPIIRVMTFVGHASGKSTKGFTQKEQLEVVKQ FRDGGYNTLVSTCVGEEGLDIGEVDLIICFDSQKSPIRLVQRMGRTGRKRQGRIVIILSEGREERIYNQSQSNKRSIYKAISSNRQVLHF -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for ACSS1-FANCM |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| Tgene | FANCM | chr20:25000646 | chr14:45628299 | ENST00000267430 | 7 | 23 | 661_800 | 465.3333333333333 | 2049.0 | CENPS/CENPSX | |
| Tgene | FANCM | chr20:25000646 | chr14:45628299 | ENST00000556036 | 7 | 11 | 661_800 | 465.3333333333333 | 670.0 | CENPS/CENPSX | |
| Tgene | FANCM | chr20:25000646 | chr14:45628299 | ENST00000267430 | 7 | 23 | 1727_2048 | 465.3333333333333 | 2049.0 | FAAP24 | |
| Tgene | FANCM | chr20:25000646 | chr14:45628299 | ENST00000556036 | 7 | 11 | 1727_2048 | 465.3333333333333 | 670.0 | FAAP24 |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for ACSS1-FANCM |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for ACSS1-FANCM |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | C0015625 | Fanconi Anemia | 6 | CTD_human;GENOMICS_ENGLAND | |
| Tgene | C0023465 | Acute monocytic leukemia | 1 | GENOMICS_ENGLAND | |
| Tgene | C0023467 | Leukemia, Myelocytic, Acute | 1 | GENOMICS_ENGLAND | |
| Tgene | C0030312 | Pancytopenia | 1 | GENOMICS_ENGLAND | |
| Tgene | C0265219 | Miller Dieker syndrome | 1 | GENOMICS_ENGLAND | |
| Tgene | C0278996 | Malignant Head and Neck Neoplasm | 1 | GENOMICS_ENGLAND | |
| Tgene | C1855710 | Bone marrow hypocellularity | 1 | GENOMICS_ENGLAND | |
| Tgene | C3463824 | MYELODYSPLASTIC SYNDROME | 1 | GENOMICS_ENGLAND | |
| Tgene | C4228778 | Abnormality of radial ray | 1 | GENOMICS_ENGLAND |
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