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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Diseases

Fusion gene:CIRH1A-ZFPM1 (FusionGDB2 ID:HG84916TG161882)

Fusion Gene Summary for CIRH1A-ZFPM1

check button Fusion gene summary
Fusion gene informationFusion gene name: CIRH1A-ZFPM1
Fusion gene ID: hg84916tg161882
HgeneTgene
Gene symbol

CIRH1A

ZFPM1

Gene ID

84916

161882

Gene nameUTP4 small subunit processome componentzinc finger protein, FOG family member 1
SynonymsCIRH1A|CIRHIN|NAIC|TEX292FOG|FOG1|ZC2HC11A|ZNF408|ZNF89A
Cytomap('CIRH1A')('ZFPM1')

16q22.1

16q24.2

Type of geneprotein-codingprotein-coding
DescriptionU3 small nucleolar RNA-associated protein 4 homologUTP4 small subunit (SSU) processome componentUTP4, small subunit (SSU) processome component, homologcirrhosis, autosomal recessive 1A (cirhin)testis expressed gene 292zinc finger protein ZFPM1FOG-1friend of GATA 1friend of GATA protein 1zinc finger protein 89Azinc finger protein, multitype 1
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000563094, ENST00000314423, 
ENST00000352319, ENST00000569615, 
Fusion gene scores* DoF score4 X 5 X 3=606 X 5 X 3=90
# samples 56
** MAII scorelog2(5/60*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(6/90*10)=-0.584962500721156
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CIRH1A [Title/Abstract] AND ZFPM1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCIRH1A(69201088)-ZFPM1(88593221), # samples:1
Anticipated loss of major functional domain due to fusion event.CIRH1A-ZFPM1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CIRH1A-ZFPM1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCIRH1A

GO:0006355

regulation of transcription, DNA-templated

19732766

TgeneZFPM1

GO:0010724

regulation of definitive erythrocyte differentiation

15920471

TgeneZFPM1

GO:0045078

positive regulation of interferon-gamma biosynthetic process

21646796

TgeneZFPM1

GO:0045403

negative regulation of interleukin-4 biosynthetic process

21646796


check buttonFusion gene breakpoints across CIRH1A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across ZFPM1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-BR-8588CIRH1Achr16

69201088

+ZFPM1chr16

88593221

+


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Fusion Gene ORF analysis for CIRH1A-ZFPM1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000563094ENST00000319555CIRH1Achr16

69201088

+ZFPM1chr16

88593221

+
3UTR-intronENST00000563094ENST00000569086CIRH1Achr16

69201088

+ZFPM1chr16

88593221

+
5CDS-intronENST00000314423ENST00000569086CIRH1Achr16

69201088

+ZFPM1chr16

88593221

+
5CDS-intronENST00000352319ENST00000569086CIRH1Achr16

69201088

+ZFPM1chr16

88593221

+
In-frameENST00000314423ENST00000319555CIRH1Achr16

69201088

+ZFPM1chr16

88593221

+
In-frameENST00000352319ENST00000319555CIRH1Achr16

69201088

+ZFPM1chr16

88593221

+
intron-3CDSENST00000569615ENST00000319555CIRH1Achr16

69201088

+ZFPM1chr16

88593221

+
intron-intronENST00000569615ENST00000569086CIRH1Achr16

69201088

+ZFPM1chr16

88593221

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000314423CIRH1Achr1669201088+ENST00000319555ZFPM1chr1688593221+677721215447391561
ENST00000352319CIRH1Achr1669201088+ENST00000319555ZFPM1chr1688593221+629716414242591405

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000314423ENST00000319555CIRH1Achr1669201088+ZFPM1chr1688593221+0.0041803560.99581957
ENST00000352319ENST00000319555CIRH1Achr1669201088+ZFPM1chr1688593221+0.0033015430.99669844

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Fusion Genomic Features for CIRH1A-ZFPM1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CIRH1Achr1669201088+ZFPM1chr1688593221+0.0014629650.99853706
CIRH1Achr1669201088+ZFPM1chr1688593221+0.0014629650.99853706

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for CIRH1A-ZFPM1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:69201088/chr16:88593221)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000314423+1617136_181648687.0RepeatNote=WD 4
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000314423+1617182_226648687.0RepeatNote=WD 5
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000314423+1617227_275648687.0RepeatNote=WD 6
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000314423+1617276_317648687.0RepeatNote=WD 7
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000314423+1617318_377648687.0RepeatNote=WD 8
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000314423+1617378_427648687.0RepeatNote=WD 9
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000314423+1617428_475648687.0RepeatNote=WD 10
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000314423+1617476_516648687.0RepeatNote=WD 11
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000314423+1617517_566648687.0RepeatNote=WD 12
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000314423+161751_92648687.0RepeatNote=WD 2
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000314423+1617567_627648687.0RepeatNote=WD 13
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000314423+16177_50648687.0RepeatNote=WD 1
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000314423+161793_135648687.0RepeatNote=WD 3
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000352319+1314136_181533572.0RepeatNote=WD 4
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000352319+1314182_226533572.0RepeatNote=WD 5
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000352319+1314227_275533572.0RepeatNote=WD 6
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000352319+1314276_317533572.0RepeatNote=WD 7
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000352319+1314318_377533572.0RepeatNote=WD 8
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000352319+1314378_427533572.0RepeatNote=WD 9
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000352319+1314428_475533572.0RepeatNote=WD 10
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000352319+1314476_516533572.0RepeatNote=WD 11
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000352319+131451_92533572.0RepeatNote=WD 2
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000352319+13147_50533572.0RepeatNote=WD 1
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000352319+131493_135533572.0RepeatNote=WD 3
TgeneZFPM1chr16:69201088chr16:88593221ENST00000319555310235_2681341007.0Zinc fingerCCHC FOG-type 1
TgeneZFPM1chr16:69201088chr16:88593221ENST00000319555310290_3141341007.0Zinc fingerC2H2-type 1
TgeneZFPM1chr16:69201088chr16:88593221ENST00000319555310320_3421341007.0Zinc fingerC2H2-type 2
TgeneZFPM1chr16:69201088chr16:88593221ENST00000319555310348_3711341007.0Zinc fingerC2H2-type 3
TgeneZFPM1chr16:69201088chr16:88593221ENST00000319555310571_6041341007.0Zinc fingerCCHC FOG-type 2
TgeneZFPM1chr16:69201088chr16:88593221ENST00000319555310677_7101341007.0Zinc fingerCCHC FOG-type 3
TgeneZFPM1chr16:69201088chr16:88593221ENST00000319555310811_8441341007.0Zinc fingerCCHC FOG-type 4
TgeneZFPM1chr16:69201088chr16:88593221ENST00000319555310854_8771341007.0Zinc fingerC2H2-type 4
TgeneZFPM1chr16:69201088chr16:88593221ENST00000319555310968_10011341007.0Zinc fingerCCHC FOG-type 5

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000314423+1617628_666648687.0RepeatNote=WD 14
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000352319+1314517_566533572.0RepeatNote=WD 12
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000352319+1314567_627533572.0RepeatNote=WD 13
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000352319+1314628_666533572.0RepeatNote=WD 14
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000563094+115136_1810626.0RepeatNote=WD 4
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000563094+115182_2260626.0RepeatNote=WD 5
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000563094+115227_2750626.0RepeatNote=WD 6
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000563094+115276_3170626.0RepeatNote=WD 7
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000563094+115318_3770626.0RepeatNote=WD 8
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000563094+115378_4270626.0RepeatNote=WD 9
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000563094+115428_4750626.0RepeatNote=WD 10
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000563094+115476_5160626.0RepeatNote=WD 11
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000563094+115517_5660626.0RepeatNote=WD 12
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000563094+11551_920626.0RepeatNote=WD 2
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000563094+115567_6270626.0RepeatNote=WD 13
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000563094+115628_6660626.0RepeatNote=WD 14
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000563094+1157_500626.0RepeatNote=WD 1
HgeneCIRH1Achr16:69201088chr16:88593221ENST00000563094+11593_1350626.0RepeatNote=WD 3


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Fusion Gene Sequence for CIRH1A-ZFPM1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>16843_16843_1_CIRH1A-ZFPM1_CIRH1A_chr16_69201088_ENST00000314423_ZFPM1_chr16_88593221_ENST00000319555_length(transcript)=6777nt_BP=2121nt
GCGGCCAACGGGCGACAACCGAACCTCCCGCCGCCGTCGCCGCCGCCGCGAGCACTGCCTGCGCACTTCCGACTATGCGCCAGGAGCACT
TCCGGGGCAGAGCCTGAGAGCGCGCGCGCACGTGGGGCCGGGGCGGAGAGAGGCGAGCACCGGGAAGGGGAGCGTGGGGCCGCTGGAATG
GGTGAATTTAAGGTCCATCGAGTACGTTTCTTTAATTATGTTCCATCAGGAATCCGCTGTGTGGCTTACAATAACCAGTCAAACAGATTG
GCTGTTTCACGAACAGATGGCACTGTGGAAATTTATAACTTGTCAGCAAACTACTTTCAGGAGAAATTTTTCCCAGGTCATGAGTCTCGG
GCTACAGAAGCTTTGTGCTGGGCAGAAGGACAGCGACTCTTTAGTGCTGGGCTCAATGGCGAGATTATGGAGTATGATTTACAGGCGTTA
AACATCAAGTATGCTATGGATGCCTTTGGAGGACCTATTTGGAGCATGGCTGCCAGCCCCAGTGGCTCTCAACTTTTGGTTGGTTGTGAA
GATGGATCTGTGAAACTATTTCAAATTACCCCAGACAAAATCCAGTTTGAAAGAAATTTTGATCGGCAGAAAAGTCGCATCCTGAGTCTC
AGCTGGCATCCCTCTGGTACCCACATTGCAGCTGGTTCCATAGACTACATTAGTGTGTTTGATGTCAAATCAGGCAGCGCTGTTCATAAG
ATGATTGTGGACAGGCAGTATATGGGCGTGTCTAAGCGGAAGTGCATCGTGTGGGGTGTCGCCTTCTTGTCCGATGGCACTATCATAAGT
GTGGACTCTGCTGGGAAGGTGCAGTTCTGGGACTCAGCCACTGGGACGCTTGTGAAGAGCCATCTCATCGCTAATGCTGACGTGCAGTCC
ATTGCTGTAGCTGACCAAGAAGACAGTTTCGTGGTGGGCACAGCCGAGGGAACAGTCTTCCATTTTCAGCTGGTCCCTGTGACATCTAAC
AGCAGTGAGAAGCAGTGGGTGCGGACAAAACCGTTCCAGCATCACACTCATGACGTGCGCACTGTGGCCCACAGCCCAACAGCGCTGATA
TCTGGAGGCACTGACACCCACTTAGTCTTTCGTCCTCTCATGGAGAAGGTGGAAGTAAAGAATTACGATGCCGCTCTCCGAAAAATCACC
TTTCCCCACCGATGTCTCATCTCCTGTTCTAAAAAGAGGCAGCTTCTCCTCTTCCAGTTTGCTCATCACTTAGAACTTTGGCGACTGGGA
TCCACAGTTGCAACAGGCAAGAATGGGGATACTCTTCCACTCTCTAAAAATGCAGATCATTTACTGCACCTAAAGACAAAGGGTCCTGAG
AACATTATCTGTAGCTGTATCTCCCCATGTGGAAGTTGGATAGCCTATTCTACAGTTTCTCGGTTTTTTCTCTATCGGCTGAATTATGAA
CATGACAACATAAGCCTCAAAAGGGTTTCCAAAATGCCAGCATTCCTTCGCTCTGCCCTTCAGATTTTGTTTTCTGAAGATTCAACAAAG
CTCTTTGTAGCATCAAATCAAGGAGCTCTGCATATTGTTCAGCTGTCAGGAGGAAGCTTCAAGCACCTGCATGCTTTCCAGCCTCAGTCA
GGAACAGTGGAGGCCATGTGTCTTTTGGCAGTCAGTCCAGATGGGAATTGGCTAGCTGCATCAGGTACCAGTGCTGGAGTCCATGTCTAC
AACGTAAAACAGCTAAAGCTTCACTGCACGGTGCCTGCTTACAATTTCCCAGTGACTGCTATGGCTATTGCCCCCAATACCAACAACCTT
GTCATCGCTCATTCGGACCAGCAGGTATTTGAGTACAGCATCCCAGACAAACAGTATACAGATTGGAGCCGGACTGTCCAGAAGCAGGGC
TTTCACCACCTTTGGCTCCAAAGGGATACTCCTATCACACACATCAGTTTTCATCCCAAGAGACCGATGCACATCCTTCTCCATGATGCC
TACATGTTCTGCATCATTGACAAGTCATTGCCCCTTCCAAATGACAAAACCTTACTCTACAATCCATTTCCTCCCACGAATGAATCAGAT
GTCATCCGGAGGCGCACAGCTCATGCTTTTAAAATTTCTAAGATATATAAGAGCCCAGCCCTGACCCTGCTGCTGGTGGACGAGGCCTGC
TGGCTGAGGACGCTGCCCCAGGCCCTGACTGAGGCCGAGGCCAACACAGAGATCCACAGGAAGGATGACGCACTCTGGTGCAGGGTCACC
AAGCCGGTGCCTGCGGGGGGACTCCTGAGCGTGCTCCTCACGGCCGAGCCCCACAGCACCCCCGGCCACCCTGTGAAGAAGGAGCCAGCA
GAGCCCACGTGCCCGGCCCCTGCACACGACCTCCAGCTCCTGCCCCAGCAGGCCGGGATGGCCTCCATCCTTGCCACCGCAGTGATCAAC
AAAGACGTCTTCCCCTGCAAGGACTGTGGCATCTGGTACCGCAGCGAGCGCAACCTGCAGGCGCACCTGCTCTACTACTGCGCCAGCCGC
CAGGGCACCGGCTCCCCGGCCGCAGCCGCCACAGACGAGAAGCCCAAAGAGACCTACCCCAACGAGCGCGTCTGCCCCTTCCCCCAGTGC
CGCAAGAGCTGCCCCAGCGCCAGCTCCCTGGAGATCCACATGCGCAGCCACAGCGGAGAGCGGCCCTTCGTGTGCCTGATCTGCCTGTCG
GCCTTCACCACCAAGGCCAACTGCGAGCGGCACCTCAAGGTGCACACGGACACGCTGAGCGGTGTCTGCCACAGCTGTGGCTTCATCTCC
ACCACAAGGGACATCCTCTACAGCCACTTGGTCACCAACCACATGGTCTGCCAGCCTGGCTCCAAGGGTGAGATCTACTCGCCAGGGGCC
GGACACCCAGCAACCAAGCTGCCCCCAGACAGTCTGGGCAGCTTCCAGCAGCAGCACACGGCCCTGCAAGGCCCCCTGGCCTCCGCGGAC
CTGGGCCTGGCGCCCACCCCATCGCCAGGACTGGACAGAAAGGCCCTGGCCGAGGCCACCAACGGAGAGGCCAGAGCGGAGCCTCTGGCC
CAGAATGGAGGCAGCAGCGAGCCCCCGGCGGCCCCCAGGAGCATCAAGGTGGAGGCGGTGGAGGAGCCGGAGGCGGCCCCCATCCTGGGC
CCCGGAGAGCCTGGGCCCCAGGCCCCGTCGCGGACGCCGTCGCCGCGCAGCCCCGCCCCGGCCAGGGTCAAGGCCGAGCTGTCCAGCCCC
ACGCCGGGCTCCAGCCCGGTGCCCGGCGAGCTGGGCCTGGCCGGGGCCCTGTTCCTTCCGCAGTACGTGTTCGGGCCCGACGCGGCGCCC
CCCGCCTCGGAGATCCTGGCCAAGATGTCCGAGCTGGTGCACAGCCGGCTGCAGCAGGGCGCGGGCGCGGGCGCCGGCGGCGCGCAGACC
GGGCTCTTCCCCGGGGCCCCCAAGGGCGCTACGTGCTTCGAGTGCGAGATCACCTTCAGCAACGTCAACAACTACTACGTGCACAAGCGC
CTCTACTGTTCAGGCCGCCGTGCGCCCGAGGACGCGCCTGCCGCGCGCAGGCCCAAGGCGCCCCCCGGCCCGGCCCGCGCGCCCCCCGGC
CAGCCCGCCGAACCCGACGCGCCGCGCTCGTCCCCGGGCCCCGGAGCGCGCGAGGAGGGGGCTGGGGGCGCGGCCACGCCCGAGGACGGC
GCGGGCGGCCGGGGCAGCGAGGGCAGCCAGAGCCCGGGTAGCTCCGTGGACGACGCGGAGGACGACCCCAGCCGCACGCTGTGCGAGGCC
TGCAACATCCGCTTCAGCCGCCACGAGACCTACACCGTGCACAAGCGGTACTACTGCGCCTCGCGCCACGACCCGCCGCCGCGCCGACCG
GCCGCGCCCCCGGGACCCCCTGGGCCGGCCGCGCCCCCGGCCCCCTCTCCCGCCGCGCCTGTGCGCACGCGCAGACGCCGCAAGCTCTAC
GAGCTGCACGCGGCCGGCGCCCCGCCCCCCCCGCCGCCCGGCCACGCCCCCGCGCCCGAGTCGCCGCGGCCCGGAAGCGGAAGCGGAAGC
GGCCCCGGCCTCGCCCCTGCGCGCTCGCCCGGCCCCGCGGCCGACGGCCCCATCGACCTGAGCAAGAAGCCGCGGCGCCCGCTCCCCGGA
GCCCCGGCACCGGCGCTGGCCGACTACCACGAGTGCACGGCCTGCCGCGTGAGCTTCCACAGCCTCGAGGCCTACCTGGCGCACAAGAAG
TACTCGTGCCCCGCTGCGCCACCGCCCGGCGCGCTCGGCCTGCCCGCCGCCGCCTGCCCCTACTGCCCCCCGAACGGCCCGGTGCGCGGG
GACCTGCTGGAGCATTTCCGCCTGGCGCACGGCCTGCTGCTCGGCGCGCCCCTGGCCGGCCCGGGGGTCGAGGCCCGGACGCCGGCCGAC
CGCGGCCCCTCGCCCGCTCCCGCCCCCGCCGCCTCCCCGCAGCCCGGGTCCCGTGGCCCCCGGGACGGCCTCGGCCCGGAGCCCCAGGAG
CCGCCGCCCGGCCCGCCCCCGTCCCCGGCCGCCGCGCCCGAGGCCGTGCCGCCCCCGCCGGCGCCCCCCTCCTACTCGGACAAGGGCGTC
CAGACTCCCAGCAAGGGCACGCCGGCGCCGCTGCCCAACGGCAACCACCGGTACTGCCGTCTTTGCAACATCAAGTTCAGCAGCCTGTCC
ACCTTCATCGCCCACAAGAAGTATTACTGCTCCTCGCACGCCGCCGAGCACGTGAAGTGAGCGCCCACACTACAGCCGCAGACGCTTTGC
ACGCCCCGCTGCGATGCGGGGAGGGGGCCGCCCCCAGGCCGCACGGACTGCCGCTCCTGGGAACCCCGCCACGCACAGGCCTCGGCGGAG
GGGGCCGCAGGGGGCAGCGCCCGCCTGGACCCTTGGCACTTAATAAAGAAGTTCAGTTTGATGAGCATGGTGGTGGGCCAGCCTAGTTCT
CTGAGCCAGCAGGCACACGCAGCCAGTGTCACATCCAGCCCTGCTGTGTACACAGGCCACTGCGGCCCGGAGTGGCTGGGCCCCTGCCGG
AGTTACACCACTGGGTGCTAAGAGCTAGACCGAGCGTCAGGTCGGAGGCCACAGCACACACTGAACCACTGCAGGGCCAGCCGCTCTGGG
CCTACCCCACCCCAGCCCTGTCCATACCCCCCTAGGGAGAGCAGCCTCCACACTGCTGACCCTCTCCACGGTCTACTTGGCCGCCAGACA
CGGAAGAGAGGGGCACTGACCTGGCTGGCCATCCCCCAACCCTGCATGGTCCTGGGGGTCCGATGTCCCCCATCCAGTCACAGACCACCA
GGGATGGCAGGGGTGGGGGCGCCCTGGGGAGGATGAAGCCCTGTGGTGGCCAAGGCTGGGGGAAGAACAGGCGAGTAGGTGGACAGGAGA
GGGAGACCGAGGCCGAAGCATTCCCTGGCCTCGAGGGGGTCCTGATGCTCACTGGTGGGTGCATCTCTCCCTCAGAGCCAGGGCTGAGGA
CAACCGTGTGGTGGAGTCACCTGTGGTGGCTGAGTCGGTGCAAGGGTCAGGGCACCCCCACCCCCCGTCTTCCCTGCCCTGCTGGGCTGT
ATGGGCCGGCCACACTGAGGGAGTACTTGGCTGACCGCGTTCAGCCACGGTGTCACCGTGCCGTTTGCAGCTGGGTGGCTGTGGGCAGCC
TCCAGCGTGCTTTCTCACTGGAGAACAAAAACACTCTTCTATTCCCAACGTCACTTTATTTTTTTATTTTTGGGTCTCACTCTCTTGCCC
AGGCTGGAGTCCCTGGGATACTCACGGCTCATTGCAGCCTTGACCTCGTGAGCTCAAGTGATCTTCCCACCTCAGTTTCCTCAGTAGCTG
GGGCTACAGGTGTACACCACCATGCCCAGCTAGTTTTTGTGTTTTTTGTAGAAATGGTGTCTCCCTATGTTGCCCAGGCTGGGCAACCCT
ATATTTTTTAGAGCTAAGGTCTTGTTCGGTTCCCCAGGCTGAAGTTCAGTGGCACGATCATAAGTCACTGCAGCCTCAAACTCCTGAGCT
GAAACCATCTTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGCTTGACCCACCACACCTGGCTAACTTTTAAAACATTTTTATAGA
GACAGGGTCTTCCTGTGTTGCCCAAGATGGTCTCAAACTCCTGACCTCCAGTGCTCCTGCAGCCTCAGCCTCCCAGAACATTAGGATGAC
AGGCGCGAGCTACCATTCCCAGCCCATTTCCAACTCTACTTGAACTAGCTGCATTTTTTTCAGCTTTGCCCAGCAGCCCTGGTGAGTGCA
GGCAAAGAAGGCAGCGGCCTCTTGCCTCAGAAGCCCGAGGCACTTCCCAGCCAGTCCAGGGCTCGCTCTCCTGCCCGCAGCTCGTGGGCC
TGGGTCTGCAGCGCTTTCAGTGGTCTCTGATGTCTTTGTCCACCTGCCCACTAGGGTCTGGCCAGATGGGGCCCGTAGCCAAGGCCAATG
GACAGACATGGCTTCCACCCCCTCCCAGGGACCTGAGCTCCAGGGAAGGCAAGCAGCCTTTTCCTCACAGACACCCCTTCTGTTGAAGAC
CAGGTGATAGCGGGGACGGGAGGCACGGACCCCTCAAGTCTGCTCATCATTTGCATTGTTGTGCATGAATTTGCGTGGAGGGTTCAGGAG
GCTCTGCCCCCAAGTCCTCCCCAGGTGCGGGCGCAGGGTACAAGATGTTCTAAAAAATAGAAACCTGGTGGGGGGTTGTCACTGTGTGTA

>16843_16843_1_CIRH1A-ZFPM1_CIRH1A_chr16_69201088_ENST00000314423_ZFPM1_chr16_88593221_ENST00000319555_length(amino acids)=1561AA_BP=1191
MPAHFRLCARSTSGAEPESARARGAGAERGEHREGERGAAGMGEFKVHRVRFFNYVPSGIRCVAYNNQSNRLAVSRTDGTVEIYNLSANY
FQEKFFPGHESRATEALCWAEGQRLFSAGLNGEIMEYDLQALNIKYAMDAFGGPIWSMAASPSGSQLLVGCEDGSVKLFQITPDKIQFER
NFDRQKSRILSLSWHPSGTHIAAGSIDYISVFDVKSGSAVHKMIVDRQYMGVSKRKCIVWGVAFLSDGTIISVDSAGKVQFWDSATGTLV
KSHLIANADVQSIAVADQEDSFVVGTAEGTVFHFQLVPVTSNSSEKQWVRTKPFQHHTHDVRTVAHSPTALISGGTDTHLVFRPLMEKVE
VKNYDAALRKITFPHRCLISCSKKRQLLLFQFAHHLELWRLGSTVATGKNGDTLPLSKNADHLLHLKTKGPENIICSCISPCGSWIAYST
VSRFFLYRLNYEHDNISLKRVSKMPAFLRSALQILFSEDSTKLFVASNQGALHIVQLSGGSFKHLHAFQPQSGTVEAMCLLAVSPDGNWL
AASGTSAGVHVYNVKQLKLHCTVPAYNFPVTAMAIAPNTNNLVIAHSDQQVFEYSIPDKQYTDWSRTVQKQGFHHLWLQRDTPITHISFH
PKRPMHILLHDAYMFCIIDKSLPLPNDKTLLYNPFPPTNESDVIRRRTAHAFKISKIYKSPALTLLLVDEACWLRTLPQALTEAEANTEI
HRKDDALWCRVTKPVPAGGLLSVLLTAEPHSTPGHPVKKEPAEPTCPAPAHDLQLLPQQAGMASILATAVINKDVFPCKDCGIWYRSERN
LQAHLLYYCASRQGTGSPAAAATDEKPKETYPNERVCPFPQCRKSCPSASSLEIHMRSHSGERPFVCLICLSAFTTKANCERHLKVHTDT
LSGVCHSCGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGAGHPATKLPPDSLGSFQQQHTALQGPLASADLGLAPTPSPGLDRKALAE
ATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQAPSRTPSPRSPAPARVKAELSSPTPGSSPVPGELGLAGALF
LPQYVFGPDAAPPASEILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNNYYVHKRLYCSGRRAPEDAPAARRP
KAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGGRGSEGSQSPGSSVDDAEDDPSRTLCEACNIRFSRHETYTVHKRYY
CASRHDPPPRRPAAPPGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRPGSGSGSGPGLAPARSPGPAADGPI
DLSKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPPNGPVRGDLLEHFRLAHGLLLGAPL
AGPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPSYSDKGVQTPSKGTPAPLPNGNHRY

--------------------------------------------------------------
>16843_16843_2_CIRH1A-ZFPM1_CIRH1A_chr16_69201088_ENST00000352319_ZFPM1_chr16_88593221_ENST00000319555_length(transcript)=6297nt_BP=1641nt
GAGAGAGGCGAGCACCGGGAAGGGGAGCGTGGGGCCGCTGGAATGGGTGAATTTAAGGTCCATCGAGTACGTTTCTTTAATTATGTTCCA
TCAGGAATCCGCTGTGTGGCTTACAATAACCAGTCAAACAGATTGGCTGTTTCACGAACAGATGGCACTGTGGAAATTTATAACTTGTCA
GCAAACTACTTTCAGGAGAAATTTTTCCCAGGTCATGAGTCTCGGGCTACAGAAGCTTTGTGCTGGGCAGAAGGACAGCGACTCTTTAGT
GCTGGGCTCAATGGCGAGATTATGGAGTATGATTTACAGGCGTTAAACATCAAGTATGCTATGGATGCCTTTGGAGGACCTATTTGGAGC
ATGGCTGCCAGCCCCAGTGGCTCTCAACTTTTGGTTGGTTGTGAAGATGGATCTGTGAAACTATTTCAAATTACCCCAGACAAAATCCAG
TTTGAAAGAAATTTTGATCGGCAGAAAAGTCGCATCCTGAGTCTCAGCTGGCATCCCTCTGGTACCCACATTGCAGCTGGTTCCATAGAC
TACATTAGTGTGTTTGATGTCAAATCAGGCAGCGCTGTTCATAAGATGATTGTGGACAGGCAGTATATGGGCGTGTCTAAGCGGAAGTGC
ATCGTGTGGGGTGTCGCCTTCTTGTCCGATGGCACTATCATAAGTGTGGACTCTGCTGGGAAGGTGCAGTTCTGGGACTCAGCCACTGGG
ACGCTTGTGAAGAGCCATCTCATCGCTAATGCTGACGTGCAGTCCATTGCTGTAGCTGACCAAGAAGACAGTTTCGTGGTGGGCACAGCC
GAGGGAACAGTCTTCCATTTTCAGCTGGTCCCTGTGACATCTAACAGCAGTGAGAAGCAGTGGGTGCGGACAAAACCGTTCCAGCATCAC
ACTCATGACGTGCGCACTGTGGCCCACAGCCCAACAGCGCTGATATCTGGAGGCACTGACACCCACTTAGTCTTTCGTCCTCTCATGGAG
AAGGTGGAAGTAAAGAATTACGATGCCGCTCTCCGAAAAATCACCTTTCCCCACCGATGTCTCATCTCCTGTTCTAAAAAGAGGCAGCTT
CTCCTCTTCCAGTTTGCTCATCACTTAGAACTTTGGCGACTGGGATCCACAGTTGCAACAGGAACAGTGGAGGCCATGTGTCTTTTGGCA
GTCAGTCCAGATGGGAATTGGCTAGCTGCATCAGGTACCAGTGCTGGAGTCCATGTCTACAACGTAAAACAGCTAAAGCTTCACTGCACG
GTGCCTGCTTACAATTTCCCAGTGACTGCTATGGCTATTGCCCCCAATACCAACAACCTTGTCATCGCTCATTCGGACCAGCAGGTATTT
GAGTACAGCATCCCAGACAAACAGTATACAGATTGGAGCCGGACTGTCCAGAAGCAGGGCTTTCACCACCTTTGGCTCCAAAGGGATACT
CCTATCACACACATCAGTTTTCATCCCAAGAGACCGATGCACATCCTTCTCCATGATGCCTACATGTTCTGCATCATTGACAAGTCATTG
CCCCTTCCAAATGACAAAACCTTACTCTACAATCCATTTCCTCCCACGAATGAATCAGATGTCATCCGGAGGCGCACAGCTCATGCTTTT
AAAATTTCTAAGATATATAAGAGCCCAGCCCTGACCCTGCTGCTGGTGGACGAGGCCTGCTGGCTGAGGACGCTGCCCCAGGCCCTGACT
GAGGCCGAGGCCAACACAGAGATCCACAGGAAGGATGACGCACTCTGGTGCAGGGTCACCAAGCCGGTGCCTGCGGGGGGACTCCTGAGC
GTGCTCCTCACGGCCGAGCCCCACAGCACCCCCGGCCACCCTGTGAAGAAGGAGCCAGCAGAGCCCACGTGCCCGGCCCCTGCACACGAC
CTCCAGCTCCTGCCCCAGCAGGCCGGGATGGCCTCCATCCTTGCCACCGCAGTGATCAACAAAGACGTCTTCCCCTGCAAGGACTGTGGC
ATCTGGTACCGCAGCGAGCGCAACCTGCAGGCGCACCTGCTCTACTACTGCGCCAGCCGCCAGGGCACCGGCTCCCCGGCCGCAGCCGCC
ACAGACGAGAAGCCCAAAGAGACCTACCCCAACGAGCGCGTCTGCCCCTTCCCCCAGTGCCGCAAGAGCTGCCCCAGCGCCAGCTCCCTG
GAGATCCACATGCGCAGCCACAGCGGAGAGCGGCCCTTCGTGTGCCTGATCTGCCTGTCGGCCTTCACCACCAAGGCCAACTGCGAGCGG
CACCTCAAGGTGCACACGGACACGCTGAGCGGTGTCTGCCACAGCTGTGGCTTCATCTCCACCACAAGGGACATCCTCTACAGCCACTTG
GTCACCAACCACATGGTCTGCCAGCCTGGCTCCAAGGGTGAGATCTACTCGCCAGGGGCCGGACACCCAGCAACCAAGCTGCCCCCAGAC
AGTCTGGGCAGCTTCCAGCAGCAGCACACGGCCCTGCAAGGCCCCCTGGCCTCCGCGGACCTGGGCCTGGCGCCCACCCCATCGCCAGGA
CTGGACAGAAAGGCCCTGGCCGAGGCCACCAACGGAGAGGCCAGAGCGGAGCCTCTGGCCCAGAATGGAGGCAGCAGCGAGCCCCCGGCG
GCCCCCAGGAGCATCAAGGTGGAGGCGGTGGAGGAGCCGGAGGCGGCCCCCATCCTGGGCCCCGGAGAGCCTGGGCCCCAGGCCCCGTCG
CGGACGCCGTCGCCGCGCAGCCCCGCCCCGGCCAGGGTCAAGGCCGAGCTGTCCAGCCCCACGCCGGGCTCCAGCCCGGTGCCCGGCGAG
CTGGGCCTGGCCGGGGCCCTGTTCCTTCCGCAGTACGTGTTCGGGCCCGACGCGGCGCCCCCCGCCTCGGAGATCCTGGCCAAGATGTCC
GAGCTGGTGCACAGCCGGCTGCAGCAGGGCGCGGGCGCGGGCGCCGGCGGCGCGCAGACCGGGCTCTTCCCCGGGGCCCCCAAGGGCGCT
ACGTGCTTCGAGTGCGAGATCACCTTCAGCAACGTCAACAACTACTACGTGCACAAGCGCCTCTACTGTTCAGGCCGCCGTGCGCCCGAG
GACGCGCCTGCCGCGCGCAGGCCCAAGGCGCCCCCCGGCCCGGCCCGCGCGCCCCCCGGCCAGCCCGCCGAACCCGACGCGCCGCGCTCG
TCCCCGGGCCCCGGAGCGCGCGAGGAGGGGGCTGGGGGCGCGGCCACGCCCGAGGACGGCGCGGGCGGCCGGGGCAGCGAGGGCAGCCAG
AGCCCGGGTAGCTCCGTGGACGACGCGGAGGACGACCCCAGCCGCACGCTGTGCGAGGCCTGCAACATCCGCTTCAGCCGCCACGAGACC
TACACCGTGCACAAGCGGTACTACTGCGCCTCGCGCCACGACCCGCCGCCGCGCCGACCGGCCGCGCCCCCGGGACCCCCTGGGCCGGCC
GCGCCCCCGGCCCCCTCTCCCGCCGCGCCTGTGCGCACGCGCAGACGCCGCAAGCTCTACGAGCTGCACGCGGCCGGCGCCCCGCCCCCC
CCGCCGCCCGGCCACGCCCCCGCGCCCGAGTCGCCGCGGCCCGGAAGCGGAAGCGGAAGCGGCCCCGGCCTCGCCCCTGCGCGCTCGCCC
GGCCCCGCGGCCGACGGCCCCATCGACCTGAGCAAGAAGCCGCGGCGCCCGCTCCCCGGAGCCCCGGCACCGGCGCTGGCCGACTACCAC
GAGTGCACGGCCTGCCGCGTGAGCTTCCACAGCCTCGAGGCCTACCTGGCGCACAAGAAGTACTCGTGCCCCGCTGCGCCACCGCCCGGC
GCGCTCGGCCTGCCCGCCGCCGCCTGCCCCTACTGCCCCCCGAACGGCCCGGTGCGCGGGGACCTGCTGGAGCATTTCCGCCTGGCGCAC
GGCCTGCTGCTCGGCGCGCCCCTGGCCGGCCCGGGGGTCGAGGCCCGGACGCCGGCCGACCGCGGCCCCTCGCCCGCTCCCGCCCCCGCC
GCCTCCCCGCAGCCCGGGTCCCGTGGCCCCCGGGACGGCCTCGGCCCGGAGCCCCAGGAGCCGCCGCCCGGCCCGCCCCCGTCCCCGGCC
GCCGCGCCCGAGGCCGTGCCGCCCCCGCCGGCGCCCCCCTCCTACTCGGACAAGGGCGTCCAGACTCCCAGCAAGGGCACGCCGGCGCCG
CTGCCCAACGGCAACCACCGGTACTGCCGTCTTTGCAACATCAAGTTCAGCAGCCTGTCCACCTTCATCGCCCACAAGAAGTATTACTGC
TCCTCGCACGCCGCCGAGCACGTGAAGTGAGCGCCCACACTACAGCCGCAGACGCTTTGCACGCCCCGCTGCGATGCGGGGAGGGGGCCG
CCCCCAGGCCGCACGGACTGCCGCTCCTGGGAACCCCGCCACGCACAGGCCTCGGCGGAGGGGGCCGCAGGGGGCAGCGCCCGCCTGGAC
CCTTGGCACTTAATAAAGAAGTTCAGTTTGATGAGCATGGTGGTGGGCCAGCCTAGTTCTCTGAGCCAGCAGGCACACGCAGCCAGTGTC
ACATCCAGCCCTGCTGTGTACACAGGCCACTGCGGCCCGGAGTGGCTGGGCCCCTGCCGGAGTTACACCACTGGGTGCTAAGAGCTAGAC
CGAGCGTCAGGTCGGAGGCCACAGCACACACTGAACCACTGCAGGGCCAGCCGCTCTGGGCCTACCCCACCCCAGCCCTGTCCATACCCC
CCTAGGGAGAGCAGCCTCCACACTGCTGACCCTCTCCACGGTCTACTTGGCCGCCAGACACGGAAGAGAGGGGCACTGACCTGGCTGGCC
ATCCCCCAACCCTGCATGGTCCTGGGGGTCCGATGTCCCCCATCCAGTCACAGACCACCAGGGATGGCAGGGGTGGGGGCGCCCTGGGGA
GGATGAAGCCCTGTGGTGGCCAAGGCTGGGGGAAGAACAGGCGAGTAGGTGGACAGGAGAGGGAGACCGAGGCCGAAGCATTCCCTGGCC
TCGAGGGGGTCCTGATGCTCACTGGTGGGTGCATCTCTCCCTCAGAGCCAGGGCTGAGGACAACCGTGTGGTGGAGTCACCTGTGGTGGC
TGAGTCGGTGCAAGGGTCAGGGCACCCCCACCCCCCGTCTTCCCTGCCCTGCTGGGCTGTATGGGCCGGCCACACTGAGGGAGTACTTGG
CTGACCGCGTTCAGCCACGGTGTCACCGTGCCGTTTGCAGCTGGGTGGCTGTGGGCAGCCTCCAGCGTGCTTTCTCACTGGAGAACAAAA
ACACTCTTCTATTCCCAACGTCACTTTATTTTTTTATTTTTGGGTCTCACTCTCTTGCCCAGGCTGGAGTCCCTGGGATACTCACGGCTC
ATTGCAGCCTTGACCTCGTGAGCTCAAGTGATCTTCCCACCTCAGTTTCCTCAGTAGCTGGGGCTACAGGTGTACACCACCATGCCCAGC
TAGTTTTTGTGTTTTTTGTAGAAATGGTGTCTCCCTATGTTGCCCAGGCTGGGCAACCCTATATTTTTTAGAGCTAAGGTCTTGTTCGGT
TCCCCAGGCTGAAGTTCAGTGGCACGATCATAAGTCACTGCAGCCTCAAACTCCTGAGCTGAAACCATCTTCCTGCCTCAGCCTCCCAAG
TAGCTGGGACTACAGGCTTGACCCACCACACCTGGCTAACTTTTAAAACATTTTTATAGAGACAGGGTCTTCCTGTGTTGCCCAAGATGG
TCTCAAACTCCTGACCTCCAGTGCTCCTGCAGCCTCAGCCTCCCAGAACATTAGGATGACAGGCGCGAGCTACCATTCCCAGCCCATTTC
CAACTCTACTTGAACTAGCTGCATTTTTTTCAGCTTTGCCCAGCAGCCCTGGTGAGTGCAGGCAAAGAAGGCAGCGGCCTCTTGCCTCAG
AAGCCCGAGGCACTTCCCAGCCAGTCCAGGGCTCGCTCTCCTGCCCGCAGCTCGTGGGCCTGGGTCTGCAGCGCTTTCAGTGGTCTCTGA
TGTCTTTGTCCACCTGCCCACTAGGGTCTGGCCAGATGGGGCCCGTAGCCAAGGCCAATGGACAGACATGGCTTCCACCCCCTCCCAGGG
ACCTGAGCTCCAGGGAAGGCAAGCAGCCTTTTCCTCACAGACACCCCTTCTGTTGAAGACCAGGTGATAGCGGGGACGGGAGGCACGGAC
CCCTCAAGTCTGCTCATCATTTGCATTGTTGTGCATGAATTTGCGTGGAGGGTTCAGGAGGCTCTGCCCCCAAGTCCTCCCCAGGTGCGG

>16843_16843_2_CIRH1A-ZFPM1_CIRH1A_chr16_69201088_ENST00000352319_ZFPM1_chr16_88593221_ENST00000319555_length(amino acids)=1405AA_BP=1035
MGEFKVHRVRFFNYVPSGIRCVAYNNQSNRLAVSRTDGTVEIYNLSANYFQEKFFPGHESRATEALCWAEGQRLFSAGLNGEIMEYDLQA
LNIKYAMDAFGGPIWSMAASPSGSQLLVGCEDGSVKLFQITPDKIQFERNFDRQKSRILSLSWHPSGTHIAAGSIDYISVFDVKSGSAVH
KMIVDRQYMGVSKRKCIVWGVAFLSDGTIISVDSAGKVQFWDSATGTLVKSHLIANADVQSIAVADQEDSFVVGTAEGTVFHFQLVPVTS
NSSEKQWVRTKPFQHHTHDVRTVAHSPTALISGGTDTHLVFRPLMEKVEVKNYDAALRKITFPHRCLISCSKKRQLLLFQFAHHLELWRL
GSTVATGTVEAMCLLAVSPDGNWLAASGTSAGVHVYNVKQLKLHCTVPAYNFPVTAMAIAPNTNNLVIAHSDQQVFEYSIPDKQYTDWSR
TVQKQGFHHLWLQRDTPITHISFHPKRPMHILLHDAYMFCIIDKSLPLPNDKTLLYNPFPPTNESDVIRRRTAHAFKISKIYKSPALTLL
LVDEACWLRTLPQALTEAEANTEIHRKDDALWCRVTKPVPAGGLLSVLLTAEPHSTPGHPVKKEPAEPTCPAPAHDLQLLPQQAGMASIL
ATAVINKDVFPCKDCGIWYRSERNLQAHLLYYCASRQGTGSPAAAATDEKPKETYPNERVCPFPQCRKSCPSASSLEIHMRSHSGERPFV
CLICLSAFTTKANCERHLKVHTDTLSGVCHSCGFISTTRDILYSHLVTNHMVCQPGSKGEIYSPGAGHPATKLPPDSLGSFQQQHTALQG
PLASADLGLAPTPSPGLDRKALAEATNGEARAEPLAQNGGSSEPPAAPRSIKVEAVEEPEAAPILGPGEPGPQAPSRTPSPRSPAPARVK
AELSSPTPGSSPVPGELGLAGALFLPQYVFGPDAAPPASEILAKMSELVHSRLQQGAGAGAGGAQTGLFPGAPKGATCFECEITFSNVNN
YYVHKRLYCSGRRAPEDAPAARRPKAPPGPARAPPGQPAEPDAPRSSPGPGAREEGAGGAATPEDGAGGRGSEGSQSPGSSVDDAEDDPS
RTLCEACNIRFSRHETYTVHKRYYCASRHDPPPRRPAAPPGPPGPAAPPAPSPAAPVRTRRRRKLYELHAAGAPPPPPPGHAPAPESPRP
GSGSGSGPGLAPARSPGPAADGPIDLSKKPRRPLPGAPAPALADYHECTACRVSFHSLEAYLAHKKYSCPAAPPPGALGLPAAACPYCPP
NGPVRGDLLEHFRLAHGLLLGAPLAGPGVEARTPADRGPSPAPAPAASPQPGSRGPRDGLGPEPQEPPPGPPPSPAAAPEAVPPPPAPPS

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CIRH1A-ZFPM1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneZFPM1chr16:69201088chr16:88593221ENST00000319555310794_800134.01007.0CTBP2
TgeneZFPM1chr16:69201088chr16:88593221ENST00000319555310330_341134.01007.0TACC3


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CIRH1A-ZFPM1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CIRH1A-ZFPM1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource