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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:GTPBP10-CDK14 (FusionGDB2 ID:HG85865TG5218)

Fusion Gene Summary for GTPBP10-CDK14

check button Fusion gene summary
Fusion gene informationFusion gene name: GTPBP10-CDK14
Fusion gene ID: hg85865tg5218
HgeneTgene
Gene symbol

GTPBP10

CDK14

Gene ID

85865

5218

Gene nameGTP binding protein 10cyclin dependent kinase 14
SynonymsObgH2|UG0751c10PFTAIRE1|PFTK1
Cytomap('GTPBP10')('CDK14')

7q21.13

7q21.13

Type of geneprotein-codingprotein-coding
DescriptionGTP-binding protein 10GTP binding protein 10 (putative)protein obg homolog 2cyclin-dependent kinase 14PFTAIRE protein kinase 1cell division protein kinase 14serine/threonine-protein kinase PFTAIRE-1
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000222511, ENST00000257659, 
ENST00000469675, 
Fusion gene scores* DoF score4 X 4 X 5=8022 X 24 X 12=6336
# samples 632
** MAII scorelog2(6/80*10)=-0.415037499278844
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(32/6336*10)=-4.30742852519225
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: GTPBP10 [Title/Abstract] AND CDK14 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointGTPBP10(90003668)-CDK14(90836479), # samples:1
GTPBP10(89976088)-CDK14(90376996), # samples:1
GTPBP10(90003668)-CDK14(90836480), # samples:1
Anticipated loss of major functional domain due to fusion event.GTPBP10-CDK14 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
GTPBP10-CDK14 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
GTPBP10-CDK14 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
GTPBP10-CDK14 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneCDK14

GO:0000086

G2/M transition of mitotic cell cycle

20059949

TgeneCDK14

GO:0060828

regulation of canonical Wnt signaling pathway

20059949


check buttonFusion gene breakpoints across GTPBP10 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across CDK14 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4COADTCGA-CA-5254-01AGTPBP10chr7

89976088

+CDK14chr7

90376996

+
ChimerDB4OVTCGA-36-1581-01AGTPBP10chr7

90003668

+CDK14chr7

90836480

+
ChimerDB4OVTCGA-36-1581GTPBP10chr7

90003668

+CDK14chr7

90836479

+


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Fusion Gene ORF analysis for GTPBP10-CDK14

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000222511ENST00000265741GTPBP10chr7

90003668

+CDK14chr7

90836480

+
5CDS-3UTRENST00000222511ENST00000265741GTPBP10chr7

90003668

+CDK14chr7

90836479

+
5CDS-3UTRENST00000222511ENST00000380050GTPBP10chr7

90003668

+CDK14chr7

90836480

+
5CDS-3UTRENST00000222511ENST00000380050GTPBP10chr7

90003668

+CDK14chr7

90836479

+
5CDS-3UTRENST00000222511ENST00000406263GTPBP10chr7

90003668

+CDK14chr7

90836480

+
5CDS-3UTRENST00000222511ENST00000406263GTPBP10chr7

90003668

+CDK14chr7

90836479

+
5CDS-3UTRENST00000222511ENST00000436577GTPBP10chr7

90003668

+CDK14chr7

90836480

+
5CDS-3UTRENST00000222511ENST00000436577GTPBP10chr7

90003668

+CDK14chr7

90836479

+
5CDS-3UTRENST00000257659ENST00000265741GTPBP10chr7

90003668

+CDK14chr7

90836480

+
5CDS-3UTRENST00000257659ENST00000265741GTPBP10chr7

90003668

+CDK14chr7

90836479

+
5CDS-3UTRENST00000257659ENST00000380050GTPBP10chr7

90003668

+CDK14chr7

90836480

+
5CDS-3UTRENST00000257659ENST00000380050GTPBP10chr7

90003668

+CDK14chr7

90836479

+
5CDS-3UTRENST00000257659ENST00000406263GTPBP10chr7

90003668

+CDK14chr7

90836480

+
5CDS-3UTRENST00000257659ENST00000406263GTPBP10chr7

90003668

+CDK14chr7

90836479

+
5CDS-3UTRENST00000257659ENST00000436577GTPBP10chr7

90003668

+CDK14chr7

90836480

+
5CDS-3UTRENST00000257659ENST00000436577GTPBP10chr7

90003668

+CDK14chr7

90836479

+
5CDS-intronENST00000222511ENST00000436577GTPBP10chr7

89976088

+CDK14chr7

90376996

+
5CDS-intronENST00000222511ENST00000496279GTPBP10chr7

89976088

+CDK14chr7

90376996

+
5CDS-intronENST00000222511ENST00000496279GTPBP10chr7

90003668

+CDK14chr7

90836480

+
5CDS-intronENST00000222511ENST00000496279GTPBP10chr7

90003668

+CDK14chr7

90836479

+
5CDS-intronENST00000257659ENST00000436577GTPBP10chr7

89976088

+CDK14chr7

90376996

+
5CDS-intronENST00000257659ENST00000496279GTPBP10chr7

89976088

+CDK14chr7

90376996

+
5CDS-intronENST00000257659ENST00000496279GTPBP10chr7

90003668

+CDK14chr7

90836480

+
5CDS-intronENST00000257659ENST00000496279GTPBP10chr7

90003668

+CDK14chr7

90836479

+
In-frameENST00000222511ENST00000265741GTPBP10chr7

89976088

+CDK14chr7

90376996

+
In-frameENST00000222511ENST00000380050GTPBP10chr7

89976088

+CDK14chr7

90376996

+
In-frameENST00000222511ENST00000406263GTPBP10chr7

89976088

+CDK14chr7

90376996

+
In-frameENST00000257659ENST00000265741GTPBP10chr7

89976088

+CDK14chr7

90376996

+
In-frameENST00000257659ENST00000380050GTPBP10chr7

89976088

+CDK14chr7

90376996

+
In-frameENST00000257659ENST00000406263GTPBP10chr7

89976088

+CDK14chr7

90376996

+
intron-3CDSENST00000469675ENST00000265741GTPBP10chr7

89976088

+CDK14chr7

90376996

+
intron-3CDSENST00000469675ENST00000380050GTPBP10chr7

89976088

+CDK14chr7

90376996

+
intron-3CDSENST00000469675ENST00000406263GTPBP10chr7

89976088

+CDK14chr7

90376996

+
intron-3UTRENST00000469675ENST00000265741GTPBP10chr7

90003668

+CDK14chr7

90836480

+
intron-3UTRENST00000469675ENST00000265741GTPBP10chr7

90003668

+CDK14chr7

90836479

+
intron-3UTRENST00000469675ENST00000380050GTPBP10chr7

90003668

+CDK14chr7

90836480

+
intron-3UTRENST00000469675ENST00000380050GTPBP10chr7

90003668

+CDK14chr7

90836479

+
intron-3UTRENST00000469675ENST00000406263GTPBP10chr7

90003668

+CDK14chr7

90836480

+
intron-3UTRENST00000469675ENST00000406263GTPBP10chr7

90003668

+CDK14chr7

90836479

+
intron-3UTRENST00000469675ENST00000436577GTPBP10chr7

90003668

+CDK14chr7

90836480

+
intron-3UTRENST00000469675ENST00000436577GTPBP10chr7

90003668

+CDK14chr7

90836479

+
intron-intronENST00000469675ENST00000436577GTPBP10chr7

89976088

+CDK14chr7

90376996

+
intron-intronENST00000469675ENST00000496279GTPBP10chr7

89976088

+CDK14chr7

90376996

+
intron-intronENST00000469675ENST00000496279GTPBP10chr7

90003668

+CDK14chr7

90836480

+
intron-intronENST00000469675ENST00000496279GTPBP10chr7

90003668

+CDK14chr7

90836479

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000257659GTPBP10chr789976088+ENST00000380050CDK14chr790376996+4605110231150375
ENST00000257659GTPBP10chr789976088+ENST00000265741CDK14chr790376996+4604110231150375
ENST00000257659GTPBP10chr789976088+ENST00000406263CDK14chr790376996+4600110231150375
ENST00000222511GTPBP10chr789976088+ENST00000380050CDK14chr790376996+459499121139375
ENST00000222511GTPBP10chr789976088+ENST00000265741CDK14chr790376996+459399121139375
ENST00000222511GTPBP10chr789976088+ENST00000406263CDK14chr790376996+458999121139375

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000257659ENST00000380050GTPBP10chr789976088+CDK14chr790376996+0.0002122220.99978775
ENST00000257659ENST00000265741GTPBP10chr789976088+CDK14chr790376996+0.0002138790.9997861
ENST00000257659ENST00000406263GTPBP10chr789976088+CDK14chr790376996+0.0002135310.99978644
ENST00000222511ENST00000380050GTPBP10chr789976088+CDK14chr790376996+0.0002139550.9997861
ENST00000222511ENST00000265741GTPBP10chr789976088+CDK14chr790376996+0.0002156260.9997844
ENST00000222511ENST00000406263GTPBP10chr789976088+CDK14chr790376996+0.0002152990.99978477

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Fusion Genomic Features for GTPBP10-CDK14


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
GTPBP10chr789976088+CDK14chr790376995+0.0196754760.98032457
GTPBP10chr790003668+CDK14chr790836479+5.30E-050.99994695
GTPBP10chr790003668+CDK14chr790836479+5.30E-050.99994695
GTPBP10chr789976088+CDK14chr790376995+0.0196754760.98032457
GTPBP10chr790003668+CDK14chr790836479+5.30E-050.99994695
GTPBP10chr790003668+CDK14chr790836479+5.30E-050.99994695

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for GTPBP10-CDK14


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:90003668/chr7:90836479)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneCDK14chr7:89976088chr7:90376996ENST00000265741114135_4191051522.6666666666667DomainProtein kinase
TgeneCDK14chr7:89976088chr7:90376996ENST00000380050215135_4191231538.0DomainProtein kinase
TgeneCDK14chr7:89976088chr7:90376996ENST00000406263114135_419771422.0DomainProtein kinase
TgeneCDK14chr7:89976088chr7:90376996ENST00000265741114141_1491051522.6666666666667Nucleotide bindingATP
TgeneCDK14chr7:89976088chr7:90376996ENST00000380050215141_1491231538.0Nucleotide bindingATP
TgeneCDK14chr7:89976088chr7:90376996ENST00000406263114141_149771422.0Nucleotide bindingATP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneGTPBP10chr7:89976088chr7:90376996ENST00000222511+11013_14811388.0DomainObg
HgeneGTPBP10chr7:89976088chr7:90376996ENST00000222511+110149_34411388.0DomainOBG-type G
HgeneGTPBP10chr7:89976088chr7:90376996ENST00000257659+1813_14811309.0DomainObg
HgeneGTPBP10chr7:89976088chr7:90376996ENST00000257659+18149_34411309.0DomainOBG-type G
HgeneGTPBP10chr7:89976088chr7:90376996ENST00000222511+110155_16211388.0Nucleotide bindingGTP
HgeneGTPBP10chr7:89976088chr7:90376996ENST00000222511+110202_20611388.0Nucleotide bindingGTP
HgeneGTPBP10chr7:89976088chr7:90376996ENST00000222511+110278_28111388.0Nucleotide bindingGTP
HgeneGTPBP10chr7:89976088chr7:90376996ENST00000257659+18155_16211309.0Nucleotide bindingGTP
HgeneGTPBP10chr7:89976088chr7:90376996ENST00000257659+18202_20611309.0Nucleotide bindingGTP
HgeneGTPBP10chr7:89976088chr7:90376996ENST00000257659+18278_28111309.0Nucleotide bindingGTP


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Fusion Gene Sequence for GTPBP10-CDK14


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>35293_35293_1_GTPBP10-CDK14_GTPBP10_chr7_89976088_ENST00000222511_CDK14_chr7_90376996_ENST00000265741_length(transcript)=4593nt_BP=99nt
AAAAAGGCCGCGCTGTACTGCGGCTTGTGCCGCTTCCGCAAGAAGGTTTCCTGGCCTGTTGCAGCCATGGTGCATTGCAGTTGCGTGTTG
TTCAGAAAGCCAACAAGTCCCAAATTTGGAAAAGCTGACTCATATGAAAAGCTGGAAAAACTAGGGGAAGGATCTTATGCTACAGTATAC
AAAGGGAAAAGCAAGGTAAATGGGAAGTTGGTAGCTCTGAAGGTGATCAGGCTGCAGGAAGAAGAAGGGACACCTTTCACAGCTATCAGG
GAAGCTTCTCTTTTAAAAGGACTAAAACATGCTAACATAGTGCTACTTCATGACATCATCCATACCAAGGAGACGCTGACACTTGTGTTT
GAATATGTGCACACTGATTTATGTCAGTACATGGACAAGCACCCTGGGGGGCTGCATCCAGATAATGTGAAGTTGTTTTTATTTCAGTTG
CTGCGAGGTCTGTCTTACATCCACCAGCGTTATATTTTGCACAGAGACCTGAAACCACAGAACCTTCTGATCAGTGACACGGGGGAGTTA
AAGCTGGCAGATTTCGGTCTTGCAAGAGCAAAATCCGTCCCTAGCCACACATACTCCAACGAAGTGGTTACCTTGTGGTACAGACCTCCA
GATGTCCTTCTAGGCTCAACAGAATATTCCACCTGCCTTGACATGTGGGGAGTAGGTTGCATCTTTGTTGAAATGATCCAAGGAGTTGCT
GCTTTTCCAGGAATGAAAGACATTCAGGATCAACTTGAACGAATATTTCTGGTTCTTGGAACACCAAATGAGGACACATGGCCTGGAGTT
CATTCTTTACCACATTTTAAGCCAGAACGCTTTACCCTGTACAGCTCTAAAAACCTTAGACAAGCATGGAATAAGCTCAGCTATGTGAAC
CATGCAGAGGACCTGGCCTCCAAGCTCCTACAATGTTCCCCAAAGAACAGACTGTCGGCACAGGCTGCCTTGAGCCACGAGTATTTTAGT
GACCTGCCGCCACGGCTATGGGAACTCACCGACATGTCTTCTATTTTTACTGTCCCAAATGTGAGATTGCAACCAGAAGCTGGAGAAAGC
ATGCGGGCCTTTGGGAAAAACAATAGTTATGGCAAAAGTCTATCAAACAGCAAGCACTGACAAGCAGCACATTCTCAAGAGCACACAGGA
TTAAGTTGTCATCATTCTGGGAAGAAAAAAAAAACATTAATGAAGAGGCCAATAATATGAAGGGAATCATGGATCAGTTTTCTTTCGCTC
CCTGTGGTGGATTTCACTTACAAGAAAATTGAAGCTGGCAAGACCCTGTTTTCTCTGCAATTTATTTAAAACCTTGCACGCATTTGGATA
CCTTGTGATTTCCAAGAACTACGTGAAGATTAAGCTTTGCTTACTGATACATGGCATGTATTCTTTTCAGTCTTTTGTGTTTGATTTTGT
TTGATTTCCCTCTGCAGCACAGCGTCTCTGTAAAGGTTTTTATGCTTTCACCAGCCATGTCTTAAATACATTAAGACAACACATTTGGTG
TTCACACTTCTTCAGTAATGTCTGAACTTGAAAGCCACAGAGTGGCATAAAACAATGTGTGTTTTCTTTGAGAGCAGTGCACATTTTGCA
ACCACTAGGAAGGAAATTTTCTGCTAAAGCAAACCCCTGTTCTCTGACTTGACAACTTGGCCCCGGACTGTGGGGCCCCACCTGTTGCTT
ACCTTTTGAGGTAATTTTGCAAATGTGGTTTTTTTACTTGGAAATAACTGCACATTTATATATAGGATATTGGACTCTGCTTAGCATTTT
CAAGCCACATAGCATGACTGTTTTTTGAATAGGTTGGAATTGAAAAAACAATTATCAAACGTTAAGAACAAAGACAGGGATAAATTGCTT
ACATTTCAACCTCTGGAGATTGAGGTAACTTTTTGTGTCTGGGTCTTGTCAACATCTAATTTTTTTCCATCCATTCTGTTACACTTTGTA
TTTTCTAACTGGAGAAAAGAGTGAGGAACAGAATGTTTTAAATCTGGTGCAAAAGAACTATATCTGCTGGATGAGCCTTGAAAGCAGTCT
TGGCCTGTTAGGGCTTACAAAGTAAATTACAAAGTGATCCAGTTCAAAGTTTGCTTAGTTACAACAAAGCACCTTTAAAAAAAATACATT
TTAAAAAAACATTCCAAGCCAATTGGAAGACATCATTGGGTTCTTACTTTAAGACATCTCCTGGAATAACTGTTCAAATGCAGGTTTTAG
AAACAATGCAGGAATCTTGCTTTAAAGATGAAAAAGGGAATGGGCCAGCTTCCCTTACTCAAGGAGTTGAGGGACCTTGGAGGATGAAGG
CGAGTATGTGACACTGGAGAAAAGTGGACCAGGCATGTCTTTTGCTTTGATCTGGAGGGAGGGCTGCCTGATGCAGGCCGGCTCCCAGTG
GGGCAGGCCTCGCTGCAGAATGCCCAGTAGTACTGCGGCCAAGGGGACAGTTAGGAGACTTCATCTAAAGCATGAAACCTAGCTCCTCTA
CACACAAATTCCTATGGAAATACCTTTGTGTACAGTGTCTTACATTTTCCTATTAGTCAGAAAGAAGGAGAGAATGAGTGAGTGCTTGAA
ATGTGTCATACTGTTTTAGGATCAAGACTAGGAATTAGGAGCCAGGTTGACAAGGACTTTTTCTGAGAGTTGGGTGAGGGTAAAGCTTTT
CTATAATCAAGCTCAATACACCAAGGAAACTGGATCCAGAATTCCTAAACTTTAAAATGGTACTGTCTGCGGAGTGGAGTATGGATGGTT
ATGTCAAAGTCATAGTTCATCCTATCCAGATGTAGCATTCATGGTAAACTTTTAAGTGCTAAGCAAGGAATTATTTACTGATTGGTTTTA
AAGAGAGCAGAAAACACCCAAGTGTAGAATGTCTACTGTTTGCTACCTAGAAATCTTTTCCATTCCTCTTTCATACATTCCAACCCACTG
GAAGTCTTTAGAGGTATTTTGATTTAAAGTATACTTAAATTAGGATTTCTTAAAGAAAACATAGGGAGAAAACTTTACATGCAATTAAAA
ATGGACTTTCCTGTGATTTGTTTTTAATCATTCATTTGGAGAAGAGGCATGACCTTTGTATTTCACTAAGTTTAAAGCAAGAGCAACTGA
TGATTAAATGTTGCTTTTTAATAAGGTTTTTAACTTGAAAATTTGAAAATATTTAATGTTGAAAGACTTCAATTAGGGCTATTAGAGTTA
TATCTCCCTGTCGTAGGCAGCTTCTTCGGAGAAGTGAAATATAACATTACTCAGTGGACGGAGAAATCTGTTTTGTTACAGAGACATGCC
TCTCAGAAGGTCAGGAGGTTTTGAGTACCTATCCTTGCCACCCATACAGGAAATCCAAAGTTTGGTGTCTCTCTCTCTCTGTCTCTTTCT
TTCTCTTTCTCCCCCCAAACCCCTCTCACTCCCTCCCTCCCTCTCTCCTTCCCCTATTTGCAATCATATTCTCCCTCTGCTTCTTTTCTC
TTCTGCCCTCCTTGTGGGCAGTCATGAAAATCAATTCAGACTGTGTTGATTAGCAGATTTATTATTCTATTGAGAAAGCACTGGAATGTT
TTGTGAGATTATTTTTATATGAAGGAATAGCCTGAACTCAAACAGATGGTAAGAATAGTACAAACACCTTAGCACATCACTGCACACACA
GTATTCTGAAAGGAGATTTGACACTTAATTCCCATTTTCTTAAAATAACAGTTTTGTTGACTTAAAAATATGAGATACATAGGATGTGAA
AAAAAATGTTTGCAGTACTCAGCAAAAAATAGGGTACATAAAGCAGGGTGGCTGTCCATCCACTGATTCTGGGGTGAGAAGCGATTTCTA
CCTCGCAAGAGTGACTAGAAAGTTTCTAGGAGCACCTCCAGGCTTGCAAAGAAAGTGAGGCCTCTTGGTATCCTTTCCTCAGTGTGTATA
TGACAGCCAGTATAATCAATACCCTAGGTTATGCGTCTATATGATACTCATCTGTGAATATTATTGGTTTTGTAATCTTTGTTATATAAG
AGGATGTTTAGGCTGTATATACTGGGGTAGATTATTGCCTGCCCCTTATACATAGGAATATGCTGCATAATTGCGCATAACTTCCATCTC
CCTTACTGGCTTGTAGGCAGAGGAAACTGTATATGTTACTGCCTTGTACTTTTCTCATACACCAAAAACACACCAAAAAAATCAATAAAA
TAAGCAATCTTCTATTCTCATTCCTTTTCCCACAGCAGCATATTTTAGAGGCACATACAAAACCTACATTCTCTAGTTGGGAGTGGATTT
TTAAAGTTTTCCTTTTATCTTTTATTTTTTTTTGTATGATGCACTGAGATGTGTACTTTCTAACAGGGGATTGGTACCTAAGAAATGTGG
TAGCATTATTCAGAAAACTATTATACTTTCAAATGACACATAGTAAGGAGAATGGAATAATACATGTTGCATATTTGTTACCAGTTGTAA
TTTGTCTGTATTATGAAAGATGTAATGGTTTGTCAGCTGTCACTGTTGTTTTCTTGTAACATGATATGGAATAAAGTATAGCAGAATCTC
CGT

>35293_35293_1_GTPBP10-CDK14_GTPBP10_chr7_89976088_ENST00000222511_CDK14_chr7_90376996_ENST00000265741_length(amino acids)=375AA_BP=1
MYCGLCRFRKKVSWPVAAMVHCSCVLFRKPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASL
LKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLAD
FGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLP
HFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQPEAGESMRAF
GKNNSYGKSLSNSKH

--------------------------------------------------------------
>35293_35293_2_GTPBP10-CDK14_GTPBP10_chr7_89976088_ENST00000222511_CDK14_chr7_90376996_ENST00000380050_length(transcript)=4594nt_BP=99nt
AAAAAGGCCGCGCTGTACTGCGGCTTGTGCCGCTTCCGCAAGAAGGTTTCCTGGCCTGTTGCAGCCATGGTGCATTGCAGTTGCGTGTTG
TTCAGAAAGCCAACAAGTCCCAAATTTGGAAAAGCTGACTCATATGAAAAGCTGGAAAAACTAGGGGAAGGATCTTATGCTACAGTATAC
AAAGGGAAAAGCAAGGTAAATGGGAAGTTGGTAGCTCTGAAGGTGATCAGGCTGCAGGAAGAAGAAGGGACACCTTTCACAGCTATCAGG
GAAGCTTCTCTTTTAAAAGGACTAAAACATGCTAACATAGTGCTACTTCATGACATCATCCATACCAAGGAGACGCTGACACTTGTGTTT
GAATATGTGCACACTGATTTATGTCAGTACATGGACAAGCACCCTGGGGGGCTGCATCCAGATAATGTGAAGTTGTTTTTATTTCAGTTG
CTGCGAGGTCTGTCTTACATCCACCAGCGTTATATTTTGCACAGAGACCTGAAACCACAGAACCTTCTGATCAGTGACACGGGGGAGTTA
AAGCTGGCAGATTTCGGTCTTGCAAGAGCAAAATCCGTCCCTAGCCACACATACTCCAACGAAGTGGTTACCTTGTGGTACAGACCTCCA
GATGTCCTTCTAGGCTCAACAGAATATTCCACCTGCCTTGACATGTGGGGAGTAGGTTGCATCTTTGTTGAAATGATCCAAGGAGTTGCT
GCTTTTCCAGGAATGAAAGACATTCAGGATCAACTTGAACGAATATTTCTGGTTCTTGGAACACCAAATGAGGACACATGGCCTGGAGTT
CATTCTTTACCACATTTTAAGCCAGAACGCTTTACCCTGTACAGCTCTAAAAACCTTAGACAAGCATGGAATAAGCTCAGCTATGTGAAC
CATGCAGAGGACCTGGCCTCCAAGCTCCTACAATGTTCCCCAAAGAACAGACTGTCGGCACAGGCTGCCTTGAGCCACGAGTATTTTAGT
GACCTGCCGCCACGGCTATGGGAACTCACCGACATGTCTTCTATTTTTACTGTCCCAAATGTGAGATTGCAACCAGAAGCTGGAGAAAGC
ATGCGGGCCTTTGGGAAAAACAATAGTTATGGCAAAAGTCTATCAAACAGCAAGCACTGACAAGCAGCACATTCTCAAGAGCACACAGGA
TTAAGTTGTCATCATTCTGGGAAGAAAAAAAAAACATTAATGAAGAGGCCAATAATATGAAGGGAATCATGGATCAGTTTTCTTTCGCTC
CCTGTGGTGGATTTCACTTACAAGAAAATTGAAGCTGGCAAGACCCTGTTTTCTCTGCAATTTATTTAAAACCTTGCACGCATTTGGATA
CCTTGTGATTTCCAAGAACTACGTGAAGATTAAGCTTTGCTTACTGATACATGGCATGTATTCTTTTCAGTCTTTTGTGTTTGATTTTGT
TTGATTTCCCTCTGCAGCACAGCGTCTCTGTAAAGGTTTTTATGCTTTCACCAGCCATGTCTTAAATACATTAAGACAACACATTTGGTG
TTCACACTTCTTCAGTAATGTCTGAACTTGAAAGCCACAGAGTGGCATAAAACAATGTGTGTTTTCTTTGAGAGCAGTGCACATTTTGCA
ACCACTAGGAAGGAAATTTTCTGCTAAAGCAAACCCCTGTTCTCTGACTTGACAACTTGGCCCCGGACTGTGGGGCCCCACCTGTTGCTT
ACCTTTTGAGGTAATTTTGCAAATGTGGTTTTTTTACTTGGAAATAACTGCACATTTATATATAGGATATTGGACTCTGCTTAGCATTTT
CAAGCCACATAGCATGACTGTTTTTTGAATAGGTTGGAATTGAAAAAACAATTATCAAACGTTAAGAACAAAGACAGGGATAAATTGCTT
ACATTTCAACCTCTGGAGATTGAGGTAACTTTTTGTGTCTGGGTCTTGTCAACATCTAATTTTTTTCCATCCATTCTGTTACACTTTGTA
TTTTCTAACTGGAGAAAAGAGTGAGGAACAGAATGTTTTAAATCTGGTGCAAAAGAACTATATCTGCTGGATGAGCCTTGAAAGCAGTCT
TGGCCTGTTAGGGCTTACAAAGTAAATTACAAAGTGATCCAGTTCAAAGTTTGCTTAGTTACAACAAAGCACCTTTAAAAAAAATACATT
TTAAAAAAACATTCCAAGCCAATTGGAAGACATCATTGGGTTCTTACTTTAAGACATCTCCTGGAATAACTGTTCAAATGCAGGTTTTAG
AAACAATGCAGGAATCTTGCTTTAAAGATGAAAAAGGGAATGGGCCAGCTTCCCTTACTCAAGGAGTTGAGGGACCTTGGAGGATGAAGG
CGAGTATGTGACACTGGAGAAAAGTGGACCAGGCATGTCTTTTGCTTTGATCTGGAGGGAGGGCTGCCTGATGCAGGCCGGCTCCCAGTG
GGGCAGGCCTCGCTGCAGAATGCCCAGTAGTACTGCGGCCAAGGGGACAGTTAGGAGACTTCATCTAAAGCATGAAACCTAGCTCCTCTA
CACACAAATTCCTATGGAAATACCTTTGTGTACAGTGTCTTACATTTTCCTATTAGTCAGAAAGAAGGAGAGAATGAGTGAGTGCTTGAA
ATGTGTCATACTGTTTTAGGATCAAGACTAGGAATTAGGAGCCAGGTTGACAAGGACTTTTTCTGAGAGTTGGGTGAGGGTAAAGCTTTT
CTATAATCAAGCTCAATACACCAAGGAAACTGGATCCAGAATTCCTAAACTTTAAAATGGTACTGTCTGCGGAGTGGAGTATGGATGGTT
ATGTCAAAGTCATAGTTCATCCTATCCAGATGTAGCATTCATGGTAAACTTTTAAGTGCTAAGCAAGGAATTATTTACTGATTGGTTTTA
AAGAGAGCAGAAAACACCCAAGTGTAGAATGTCTACTGTTTGCTACCTAGAAATCTTTTCCATTCCTCTTTCATACATTCCAACCCACTG
GAAGTCTTTAGAGGTATTTTGATTTAAAGTATACTTAAATTAGGATTTCTTAAAGAAAACATAGGGAGAAAACTTTACATGCAATTAAAA
ATGGACTTTCCTGTGATTTGTTTTTAATCATTCATTTGGAGAAGAGGCATGACCTTTGTATTTCACTAAGTTTAAAGCAAGAGCAACTGA
TGATTAAATGTTGCTTTTTAATAAGGTTTTTAACTTGAAAATTTGAAAATATTTAATGTTGAAAGACTTCAATTAGGGCTATTAGAGTTA
TATCTCCCTGTCGTAGGCAGCTTCTTCGGAGAAGTGAAATATAACATTACTCAGTGGACGGAGAAATCTGTTTTGTTACAGAGACATGCC
TCTCAGAAGGTCAGGAGGTTTTGAGTACCTATCCTTGCCACCCATACAGGAAATCCAAAGTTTGGTGTCTCTCTCTCTCTGTCTCTTTCT
TTCTCTTTCTCCCCCCAAACCCCTCTCACTCCCTCCCTCCCTCTCTCCTTCCCCTATTTGCAATCATATTCTCCCTCTGCTTCTTTTCTC
TTCTGCCCTCCTTGTGGGCAGTCATGAAAATCAATTCAGACTGTGTTGATTAGCAGATTTATTATTCTATTGAGAAAGCACTGGAATGTT
TTGTGAGATTATTTTTATATGAAGGAATAGCCTGAACTCAAACAGATGGTAAGAATAGTACAAACACCTTAGCACATCACTGCACACACA
GTATTCTGAAAGGAGATTTGACACTTAATTCCCATTTTCTTAAAATAACAGTTTTGTTGACTTAAAAATATGAGATACATAGGATGTGAA
AAAAAATGTTTGCAGTACTCAGCAAAAAATAGGGTACATAAAGCAGGGTGGCTGTCCATCCACTGATTCTGGGGTGAGAAGCGATTTCTA
CCTCGCAAGAGTGACTAGAAAGTTTCTAGGAGCACCTCCAGGCTTGCAAAGAAAGTGAGGCCTCTTGGTATCCTTTCCTCAGTGTGTATA
TGACAGCCAGTATAATCAATACCCTAGGTTATGCGTCTATATGATACTCATCTGTGAATATTATTGGTTTTGTAATCTTTGTTATATAAG
AGGATGTTTAGGCTGTATATACTGGGGTAGATTATTGCCTGCCCCTTATACATAGGAATATGCTGCATAATTGCGCATAACTTCCATCTC
CCTTACTGGCTTGTAGGCAGAGGAAACTGTATATGTTACTGCCTTGTACTTTTCTCATACACCAAAAACACACCAAAAAAATCAATAAAA
TAAGCAATCTTCTATTCTCATTCCTTTTCCCACAGCAGCATATTTTAGAGGCACATACAAAACCTACATTCTCTAGTTGGGAGTGGATTT
TTAAAGTTTTCCTTTTATCTTTTATTTTTTTTTGTATGATGCACTGAGATGTGTACTTTCTAACAGGGGATTGGTACCTAAGAAATGTGG
TAGCATTATTCAGAAAACTATTATACTTTCAAATGACACATAGTAAGGAGAATGGAATAATACATGTTGCATATTTGTTACCAGTTGTAA
TTTGTCTGTATTATGAAAGATGTAATGGTTTGTCAGCTGTCACTGTTGTTTTCTTGTAACATGATATGGAATAAAGTATAGCAGAATCTC
CGTA

>35293_35293_2_GTPBP10-CDK14_GTPBP10_chr7_89976088_ENST00000222511_CDK14_chr7_90376996_ENST00000380050_length(amino acids)=375AA_BP=1
MYCGLCRFRKKVSWPVAAMVHCSCVLFRKPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASL
LKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLAD
FGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLP
HFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQPEAGESMRAF
GKNNSYGKSLSNSKH

--------------------------------------------------------------
>35293_35293_3_GTPBP10-CDK14_GTPBP10_chr7_89976088_ENST00000222511_CDK14_chr7_90376996_ENST00000406263_length(transcript)=4589nt_BP=99nt
AAAAAGGCCGCGCTGTACTGCGGCTTGTGCCGCTTCCGCAAGAAGGTTTCCTGGCCTGTTGCAGCCATGGTGCATTGCAGTTGCGTGTTG
TTCAGAAAGCCAACAAGTCCCAAATTTGGAAAAGCTGACTCATATGAAAAGCTGGAAAAACTAGGGGAAGGATCTTATGCTACAGTATAC
AAAGGGAAAAGCAAGGTAAATGGGAAGTTGGTAGCTCTGAAGGTGATCAGGCTGCAGGAAGAAGAAGGGACACCTTTCACAGCTATCAGG
GAAGCTTCTCTTTTAAAAGGACTAAAACATGCTAACATAGTGCTACTTCATGACATCATCCATACCAAGGAGACGCTGACACTTGTGTTT
GAATATGTGCACACTGATTTATGTCAGTACATGGACAAGCACCCTGGGGGGCTGCATCCAGATAATGTGAAGTTGTTTTTATTTCAGTTG
CTGCGAGGTCTGTCTTACATCCACCAGCGTTATATTTTGCACAGAGACCTGAAACCACAGAACCTTCTGATCAGTGACACGGGGGAGTTA
AAGCTGGCAGATTTCGGTCTTGCAAGAGCAAAATCCGTCCCTAGCCACACATACTCCAACGAAGTGGTTACCTTGTGGTACAGACCTCCA
GATGTCCTTCTAGGCTCAACAGAATATTCCACCTGCCTTGACATGTGGGGAGTAGGTTGCATCTTTGTTGAAATGATCCAAGGAGTTGCT
GCTTTTCCAGGAATGAAAGACATTCAGGATCAACTTGAACGAATATTTCTGGTTCTTGGAACACCAAATGAGGACACATGGCCTGGAGTT
CATTCTTTACCACATTTTAAGCCAGAACGCTTTACCCTGTACAGCTCTAAAAACCTTAGACAAGCATGGAATAAGCTCAGCTATGTGAAC
CATGCAGAGGACCTGGCCTCCAAGCTCCTACAATGTTCCCCAAAGAACAGACTGTCGGCACAGGCTGCCTTGAGCCACGAGTATTTTAGT
GACCTGCCGCCACGGCTATGGGAACTCACCGACATGTCTTCTATTTTTACTGTCCCAAATGTGAGATTGCAACCAGAAGCTGGAGAAAGC
ATGCGGGCCTTTGGGAAAAACAATAGTTATGGCAAAAGTCTATCAAACAGCAAGCACTGACAAGCAGCACATTCTCAAGAGCACACAGGA
TTAAGTTGTCATCATTCTGGGAAGAAAAAAAAAACATTAATGAAGAGGCCAATAATATGAAGGGAATCATGGATCAGTTTTCTTTCGCTC
CCTGTGGTGGATTTCACTTACAAGAAAATTGAAGCTGGCAAGACCCTGTTTTCTCTGCAATTTATTTAAAACCTTGCACGCATTTGGATA
CCTTGTGATTTCCAAGAACTACGTGAAGATTAAGCTTTGCTTACTGATACATGGCATGTATTCTTTTCAGTCTTTTGTGTTTGATTTTGT
TTGATTTCCCTCTGCAGCACAGCGTCTCTGTAAAGGTTTTTATGCTTTCACCAGCCATGTCTTAAATACATTAAGACAACACATTTGGTG
TTCACACTTCTTCAGTAATGTCTGAACTTGAAAGCCACAGAGTGGCATAAAACAATGTGTGTTTTCTTTGAGAGCAGTGCACATTTTGCA
ACCACTAGGAAGGAAATTTTCTGCTAAAGCAAACCCCTGTTCTCTGACTTGACAACTTGGCCCCGGACTGTGGGGCCCCACCTGTTGCTT
ACCTTTTGAGGTAATTTTGCAAATGTGGTTTTTTTACTTGGAAATAACTGCACATTTATATATAGGATATTGGACTCTGCTTAGCATTTT
CAAGCCACATAGCATGACTGTTTTTTGAATAGGTTGGAATTGAAAAAACAATTATCAAACGTTAAGAACAAAGACAGGGATAAATTGCTT
ACATTTCAACCTCTGGAGATTGAGGTAACTTTTTGTGTCTGGGTCTTGTCAACATCTAATTTTTTTCCATCCATTCTGTTACACTTTGTA
TTTTCTAACTGGAGAAAAGAGTGAGGAACAGAATGTTTTAAATCTGGTGCAAAAGAACTATATCTGCTGGATGAGCCTTGAAAGCAGTCT
TGGCCTGTTAGGGCTTACAAAGTAAATTACAAAGTGATCCAGTTCAAAGTTTGCTTAGTTACAACAAAGCACCTTTAAAAAAAATACATT
TTAAAAAAACATTCCAAGCCAATTGGAAGACATCATTGGGTTCTTACTTTAAGACATCTCCTGGAATAACTGTTCAAATGCAGGTTTTAG
AAACAATGCAGGAATCTTGCTTTAAAGATGAAAAAGGGAATGGGCCAGCTTCCCTTACTCAAGGAGTTGAGGGACCTTGGAGGATGAAGG
CGAGTATGTGACACTGGAGAAAAGTGGACCAGGCATGTCTTTTGCTTTGATCTGGAGGGAGGGCTGCCTGATGCAGGCCGGCTCCCAGTG
GGGCAGGCCTCGCTGCAGAATGCCCAGTAGTACTGCGGCCAAGGGGACAGTTAGGAGACTTCATCTAAAGCATGAAACCTAGCTCCTCTA
CACACAAATTCCTATGGAAATACCTTTGTGTACAGTGTCTTACATTTTCCTATTAGTCAGAAAGAAGGAGAGAATGAGTGAGTGCTTGAA
ATGTGTCATACTGTTTTAGGATCAAGACTAGGAATTAGGAGCCAGGTTGACAAGGACTTTTTCTGAGAGTTGGGTGAGGGTAAAGCTTTT
CTATAATCAAGCTCAATACACCAAGGAAACTGGATCCAGAATTCCTAAACTTTAAAATGGTACTGTCTGCGGAGTGGAGTATGGATGGTT
ATGTCAAAGTCATAGTTCATCCTATCCAGATGTAGCATTCATGGTAAACTTTTAAGTGCTAAGCAAGGAATTATTTACTGATTGGTTTTA
AAGAGAGCAGAAAACACCCAAGTGTAGAATGTCTACTGTTTGCTACCTAGAAATCTTTTCCATTCCTCTTTCATACATTCCAACCCACTG
GAAGTCTTTAGAGGTATTTTGATTTAAAGTATACTTAAATTAGGATTTCTTAAAGAAAACATAGGGAGAAAACTTTACATGCAATTAAAA
ATGGACTTTCCTGTGATTTGTTTTTAATCATTCATTTGGAGAAGAGGCATGACCTTTGTATTTCACTAAGTTTAAAGCAAGAGCAACTGA
TGATTAAATGTTGCTTTTTAATAAGGTTTTTAACTTGAAAATTTGAAAATATTTAATGTTGAAAGACTTCAATTAGGGCTATTAGAGTTA
TATCTCCCTGTCGTAGGCAGCTTCTTCGGAGAAGTGAAATATAACATTACTCAGTGGACGGAGAAATCTGTTTTGTTACAGAGACATGCC
TCTCAGAAGGTCAGGAGGTTTTGAGTACCTATCCTTGCCACCCATACAGGAAATCCAAAGTTTGGTGTCTCTCTCTCTCTGTCTCTTTCT
TTCTCTTTCTCCCCCCAAACCCCTCTCACTCCCTCCCTCCCTCTCTCCTTCCCCTATTTGCAATCATATTCTCCCTCTGCTTCTTTTCTC
TTCTGCCCTCCTTGTGGGCAGTCATGAAAATCAATTCAGACTGTGTTGATTAGCAGATTTATTATTCTATTGAGAAAGCACTGGAATGTT
TTGTGAGATTATTTTTATATGAAGGAATAGCCTGAACTCAAACAGATGGTAAGAATAGTACAAACACCTTAGCACATCACTGCACACACA
GTATTCTGAAAGGAGATTTGACACTTAATTCCCATTTTCTTAAAATAACAGTTTTGTTGACTTAAAAATATGAGATACATAGGATGTGAA
AAAAAATGTTTGCAGTACTCAGCAAAAAATAGGGTACATAAAGCAGGGTGGCTGTCCATCCACTGATTCTGGGGTGAGAAGCGATTTCTA
CCTCGCAAGAGTGACTAGAAAGTTTCTAGGAGCACCTCCAGGCTTGCAAAGAAAGTGAGGCCTCTTGGTATCCTTTCCTCAGTGTGTATA
TGACAGCCAGTATAATCAATACCCTAGGTTATGCGTCTATATGATACTCATCTGTGAATATTATTGGTTTTGTAATCTTTGTTATATAAG
AGGATGTTTAGGCTGTATATACTGGGGTAGATTATTGCCTGCCCCTTATACATAGGAATATGCTGCATAATTGCGCATAACTTCCATCTC
CCTTACTGGCTTGTAGGCAGAGGAAACTGTATATGTTACTGCCTTGTACTTTTCTCATACACCAAAAACACACCAAAAAAATCAATAAAA
TAAGCAATCTTCTATTCTCATTCCTTTTCCCACAGCAGCATATTTTAGAGGCACATACAAAACCTACATTCTCTAGTTGGGAGTGGATTT
TTAAAGTTTTCCTTTTATCTTTTATTTTTTTTTGTATGATGCACTGAGATGTGTACTTTCTAACAGGGGATTGGTACCTAAGAAATGTGG
TAGCATTATTCAGAAAACTATTATACTTTCAAATGACACATAGTAAGGAGAATGGAATAATACATGTTGCATATTTGTTACCAGTTGTAA
TTTGTCTGTATTATGAAAGATGTAATGGTTTGTCAGCTGTCACTGTTGTTTTCTTGTAACATGATATGGAATAAAGTATAGCAGAATCT

>35293_35293_3_GTPBP10-CDK14_GTPBP10_chr7_89976088_ENST00000222511_CDK14_chr7_90376996_ENST00000406263_length(amino acids)=375AA_BP=1
MYCGLCRFRKKVSWPVAAMVHCSCVLFRKPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASL
LKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLAD
FGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLP
HFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQPEAGESMRAF
GKNNSYGKSLSNSKH

--------------------------------------------------------------
>35293_35293_4_GTPBP10-CDK14_GTPBP10_chr7_89976088_ENST00000257659_CDK14_chr7_90376996_ENST00000265741_length(transcript)=4604nt_BP=110nt
GGGGATGACGTAAAAAGGCCGCGCTGTACTGCGGCTTGTGCCGCTTCCGCAAGAAGGTTTCCTGGCCTGTTGCAGCCATGGTGCATTGCA
GTTGCGTGTTGTTCAGAAAGCCAACAAGTCCCAAATTTGGAAAAGCTGACTCATATGAAAAGCTGGAAAAACTAGGGGAAGGATCTTATG
CTACAGTATACAAAGGGAAAAGCAAGGTAAATGGGAAGTTGGTAGCTCTGAAGGTGATCAGGCTGCAGGAAGAAGAAGGGACACCTTTCA
CAGCTATCAGGGAAGCTTCTCTTTTAAAAGGACTAAAACATGCTAACATAGTGCTACTTCATGACATCATCCATACCAAGGAGACGCTGA
CACTTGTGTTTGAATATGTGCACACTGATTTATGTCAGTACATGGACAAGCACCCTGGGGGGCTGCATCCAGATAATGTGAAGTTGTTTT
TATTTCAGTTGCTGCGAGGTCTGTCTTACATCCACCAGCGTTATATTTTGCACAGAGACCTGAAACCACAGAACCTTCTGATCAGTGACA
CGGGGGAGTTAAAGCTGGCAGATTTCGGTCTTGCAAGAGCAAAATCCGTCCCTAGCCACACATACTCCAACGAAGTGGTTACCTTGTGGT
ACAGACCTCCAGATGTCCTTCTAGGCTCAACAGAATATTCCACCTGCCTTGACATGTGGGGAGTAGGTTGCATCTTTGTTGAAATGATCC
AAGGAGTTGCTGCTTTTCCAGGAATGAAAGACATTCAGGATCAACTTGAACGAATATTTCTGGTTCTTGGAACACCAAATGAGGACACAT
GGCCTGGAGTTCATTCTTTACCACATTTTAAGCCAGAACGCTTTACCCTGTACAGCTCTAAAAACCTTAGACAAGCATGGAATAAGCTCA
GCTATGTGAACCATGCAGAGGACCTGGCCTCCAAGCTCCTACAATGTTCCCCAAAGAACAGACTGTCGGCACAGGCTGCCTTGAGCCACG
AGTATTTTAGTGACCTGCCGCCACGGCTATGGGAACTCACCGACATGTCTTCTATTTTTACTGTCCCAAATGTGAGATTGCAACCAGAAG
CTGGAGAAAGCATGCGGGCCTTTGGGAAAAACAATAGTTATGGCAAAAGTCTATCAAACAGCAAGCACTGACAAGCAGCACATTCTCAAG
AGCACACAGGATTAAGTTGTCATCATTCTGGGAAGAAAAAAAAAACATTAATGAAGAGGCCAATAATATGAAGGGAATCATGGATCAGTT
TTCTTTCGCTCCCTGTGGTGGATTTCACTTACAAGAAAATTGAAGCTGGCAAGACCCTGTTTTCTCTGCAATTTATTTAAAACCTTGCAC
GCATTTGGATACCTTGTGATTTCCAAGAACTACGTGAAGATTAAGCTTTGCTTACTGATACATGGCATGTATTCTTTTCAGTCTTTTGTG
TTTGATTTTGTTTGATTTCCCTCTGCAGCACAGCGTCTCTGTAAAGGTTTTTATGCTTTCACCAGCCATGTCTTAAATACATTAAGACAA
CACATTTGGTGTTCACACTTCTTCAGTAATGTCTGAACTTGAAAGCCACAGAGTGGCATAAAACAATGTGTGTTTTCTTTGAGAGCAGTG
CACATTTTGCAACCACTAGGAAGGAAATTTTCTGCTAAAGCAAACCCCTGTTCTCTGACTTGACAACTTGGCCCCGGACTGTGGGGCCCC
ACCTGTTGCTTACCTTTTGAGGTAATTTTGCAAATGTGGTTTTTTTACTTGGAAATAACTGCACATTTATATATAGGATATTGGACTCTG
CTTAGCATTTTCAAGCCACATAGCATGACTGTTTTTTGAATAGGTTGGAATTGAAAAAACAATTATCAAACGTTAAGAACAAAGACAGGG
ATAAATTGCTTACATTTCAACCTCTGGAGATTGAGGTAACTTTTTGTGTCTGGGTCTTGTCAACATCTAATTTTTTTCCATCCATTCTGT
TACACTTTGTATTTTCTAACTGGAGAAAAGAGTGAGGAACAGAATGTTTTAAATCTGGTGCAAAAGAACTATATCTGCTGGATGAGCCTT
GAAAGCAGTCTTGGCCTGTTAGGGCTTACAAAGTAAATTACAAAGTGATCCAGTTCAAAGTTTGCTTAGTTACAACAAAGCACCTTTAAA
AAAAATACATTTTAAAAAAACATTCCAAGCCAATTGGAAGACATCATTGGGTTCTTACTTTAAGACATCTCCTGGAATAACTGTTCAAAT
GCAGGTTTTAGAAACAATGCAGGAATCTTGCTTTAAAGATGAAAAAGGGAATGGGCCAGCTTCCCTTACTCAAGGAGTTGAGGGACCTTG
GAGGATGAAGGCGAGTATGTGACACTGGAGAAAAGTGGACCAGGCATGTCTTTTGCTTTGATCTGGAGGGAGGGCTGCCTGATGCAGGCC
GGCTCCCAGTGGGGCAGGCCTCGCTGCAGAATGCCCAGTAGTACTGCGGCCAAGGGGACAGTTAGGAGACTTCATCTAAAGCATGAAACC
TAGCTCCTCTACACACAAATTCCTATGGAAATACCTTTGTGTACAGTGTCTTACATTTTCCTATTAGTCAGAAAGAAGGAGAGAATGAGT
GAGTGCTTGAAATGTGTCATACTGTTTTAGGATCAAGACTAGGAATTAGGAGCCAGGTTGACAAGGACTTTTTCTGAGAGTTGGGTGAGG
GTAAAGCTTTTCTATAATCAAGCTCAATACACCAAGGAAACTGGATCCAGAATTCCTAAACTTTAAAATGGTACTGTCTGCGGAGTGGAG
TATGGATGGTTATGTCAAAGTCATAGTTCATCCTATCCAGATGTAGCATTCATGGTAAACTTTTAAGTGCTAAGCAAGGAATTATTTACT
GATTGGTTTTAAAGAGAGCAGAAAACACCCAAGTGTAGAATGTCTACTGTTTGCTACCTAGAAATCTTTTCCATTCCTCTTTCATACATT
CCAACCCACTGGAAGTCTTTAGAGGTATTTTGATTTAAAGTATACTTAAATTAGGATTTCTTAAAGAAAACATAGGGAGAAAACTTTACA
TGCAATTAAAAATGGACTTTCCTGTGATTTGTTTTTAATCATTCATTTGGAGAAGAGGCATGACCTTTGTATTTCACTAAGTTTAAAGCA
AGAGCAACTGATGATTAAATGTTGCTTTTTAATAAGGTTTTTAACTTGAAAATTTGAAAATATTTAATGTTGAAAGACTTCAATTAGGGC
TATTAGAGTTATATCTCCCTGTCGTAGGCAGCTTCTTCGGAGAAGTGAAATATAACATTACTCAGTGGACGGAGAAATCTGTTTTGTTAC
AGAGACATGCCTCTCAGAAGGTCAGGAGGTTTTGAGTACCTATCCTTGCCACCCATACAGGAAATCCAAAGTTTGGTGTCTCTCTCTCTC
TGTCTCTTTCTTTCTCTTTCTCCCCCCAAACCCCTCTCACTCCCTCCCTCCCTCTCTCCTTCCCCTATTTGCAATCATATTCTCCCTCTG
CTTCTTTTCTCTTCTGCCCTCCTTGTGGGCAGTCATGAAAATCAATTCAGACTGTGTTGATTAGCAGATTTATTATTCTATTGAGAAAGC
ACTGGAATGTTTTGTGAGATTATTTTTATATGAAGGAATAGCCTGAACTCAAACAGATGGTAAGAATAGTACAAACACCTTAGCACATCA
CTGCACACACAGTATTCTGAAAGGAGATTTGACACTTAATTCCCATTTTCTTAAAATAACAGTTTTGTTGACTTAAAAATATGAGATACA
TAGGATGTGAAAAAAAATGTTTGCAGTACTCAGCAAAAAATAGGGTACATAAAGCAGGGTGGCTGTCCATCCACTGATTCTGGGGTGAGA
AGCGATTTCTACCTCGCAAGAGTGACTAGAAAGTTTCTAGGAGCACCTCCAGGCTTGCAAAGAAAGTGAGGCCTCTTGGTATCCTTTCCT
CAGTGTGTATATGACAGCCAGTATAATCAATACCCTAGGTTATGCGTCTATATGATACTCATCTGTGAATATTATTGGTTTTGTAATCTT
TGTTATATAAGAGGATGTTTAGGCTGTATATACTGGGGTAGATTATTGCCTGCCCCTTATACATAGGAATATGCTGCATAATTGCGCATA
ACTTCCATCTCCCTTACTGGCTTGTAGGCAGAGGAAACTGTATATGTTACTGCCTTGTACTTTTCTCATACACCAAAAACACACCAAAAA
AATCAATAAAATAAGCAATCTTCTATTCTCATTCCTTTTCCCACAGCAGCATATTTTAGAGGCACATACAAAACCTACATTCTCTAGTTG
GGAGTGGATTTTTAAAGTTTTCCTTTTATCTTTTATTTTTTTTTGTATGATGCACTGAGATGTGTACTTTCTAACAGGGGATTGGTACCT
AAGAAATGTGGTAGCATTATTCAGAAAACTATTATACTTTCAAATGACACATAGTAAGGAGAATGGAATAATACATGTTGCATATTTGTT
ACCAGTTGTAATTTGTCTGTATTATGAAAGATGTAATGGTTTGTCAGCTGTCACTGTTGTTTTCTTGTAACATGATATGGAATAAAGTAT
AGCAGAATCTCCGT

>35293_35293_4_GTPBP10-CDK14_GTPBP10_chr7_89976088_ENST00000257659_CDK14_chr7_90376996_ENST00000265741_length(amino acids)=375AA_BP=1
MYCGLCRFRKKVSWPVAAMVHCSCVLFRKPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASL
LKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLAD
FGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLP
HFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQPEAGESMRAF
GKNNSYGKSLSNSKH

--------------------------------------------------------------
>35293_35293_5_GTPBP10-CDK14_GTPBP10_chr7_89976088_ENST00000257659_CDK14_chr7_90376996_ENST00000380050_length(transcript)=4605nt_BP=110nt
GGGGATGACGTAAAAAGGCCGCGCTGTACTGCGGCTTGTGCCGCTTCCGCAAGAAGGTTTCCTGGCCTGTTGCAGCCATGGTGCATTGCA
GTTGCGTGTTGTTCAGAAAGCCAACAAGTCCCAAATTTGGAAAAGCTGACTCATATGAAAAGCTGGAAAAACTAGGGGAAGGATCTTATG
CTACAGTATACAAAGGGAAAAGCAAGGTAAATGGGAAGTTGGTAGCTCTGAAGGTGATCAGGCTGCAGGAAGAAGAAGGGACACCTTTCA
CAGCTATCAGGGAAGCTTCTCTTTTAAAAGGACTAAAACATGCTAACATAGTGCTACTTCATGACATCATCCATACCAAGGAGACGCTGA
CACTTGTGTTTGAATATGTGCACACTGATTTATGTCAGTACATGGACAAGCACCCTGGGGGGCTGCATCCAGATAATGTGAAGTTGTTTT
TATTTCAGTTGCTGCGAGGTCTGTCTTACATCCACCAGCGTTATATTTTGCACAGAGACCTGAAACCACAGAACCTTCTGATCAGTGACA
CGGGGGAGTTAAAGCTGGCAGATTTCGGTCTTGCAAGAGCAAAATCCGTCCCTAGCCACACATACTCCAACGAAGTGGTTACCTTGTGGT
ACAGACCTCCAGATGTCCTTCTAGGCTCAACAGAATATTCCACCTGCCTTGACATGTGGGGAGTAGGTTGCATCTTTGTTGAAATGATCC
AAGGAGTTGCTGCTTTTCCAGGAATGAAAGACATTCAGGATCAACTTGAACGAATATTTCTGGTTCTTGGAACACCAAATGAGGACACAT
GGCCTGGAGTTCATTCTTTACCACATTTTAAGCCAGAACGCTTTACCCTGTACAGCTCTAAAAACCTTAGACAAGCATGGAATAAGCTCA
GCTATGTGAACCATGCAGAGGACCTGGCCTCCAAGCTCCTACAATGTTCCCCAAAGAACAGACTGTCGGCACAGGCTGCCTTGAGCCACG
AGTATTTTAGTGACCTGCCGCCACGGCTATGGGAACTCACCGACATGTCTTCTATTTTTACTGTCCCAAATGTGAGATTGCAACCAGAAG
CTGGAGAAAGCATGCGGGCCTTTGGGAAAAACAATAGTTATGGCAAAAGTCTATCAAACAGCAAGCACTGACAAGCAGCACATTCTCAAG
AGCACACAGGATTAAGTTGTCATCATTCTGGGAAGAAAAAAAAAACATTAATGAAGAGGCCAATAATATGAAGGGAATCATGGATCAGTT
TTCTTTCGCTCCCTGTGGTGGATTTCACTTACAAGAAAATTGAAGCTGGCAAGACCCTGTTTTCTCTGCAATTTATTTAAAACCTTGCAC
GCATTTGGATACCTTGTGATTTCCAAGAACTACGTGAAGATTAAGCTTTGCTTACTGATACATGGCATGTATTCTTTTCAGTCTTTTGTG
TTTGATTTTGTTTGATTTCCCTCTGCAGCACAGCGTCTCTGTAAAGGTTTTTATGCTTTCACCAGCCATGTCTTAAATACATTAAGACAA
CACATTTGGTGTTCACACTTCTTCAGTAATGTCTGAACTTGAAAGCCACAGAGTGGCATAAAACAATGTGTGTTTTCTTTGAGAGCAGTG
CACATTTTGCAACCACTAGGAAGGAAATTTTCTGCTAAAGCAAACCCCTGTTCTCTGACTTGACAACTTGGCCCCGGACTGTGGGGCCCC
ACCTGTTGCTTACCTTTTGAGGTAATTTTGCAAATGTGGTTTTTTTACTTGGAAATAACTGCACATTTATATATAGGATATTGGACTCTG
CTTAGCATTTTCAAGCCACATAGCATGACTGTTTTTTGAATAGGTTGGAATTGAAAAAACAATTATCAAACGTTAAGAACAAAGACAGGG
ATAAATTGCTTACATTTCAACCTCTGGAGATTGAGGTAACTTTTTGTGTCTGGGTCTTGTCAACATCTAATTTTTTTCCATCCATTCTGT
TACACTTTGTATTTTCTAACTGGAGAAAAGAGTGAGGAACAGAATGTTTTAAATCTGGTGCAAAAGAACTATATCTGCTGGATGAGCCTT
GAAAGCAGTCTTGGCCTGTTAGGGCTTACAAAGTAAATTACAAAGTGATCCAGTTCAAAGTTTGCTTAGTTACAACAAAGCACCTTTAAA
AAAAATACATTTTAAAAAAACATTCCAAGCCAATTGGAAGACATCATTGGGTTCTTACTTTAAGACATCTCCTGGAATAACTGTTCAAAT
GCAGGTTTTAGAAACAATGCAGGAATCTTGCTTTAAAGATGAAAAAGGGAATGGGCCAGCTTCCCTTACTCAAGGAGTTGAGGGACCTTG
GAGGATGAAGGCGAGTATGTGACACTGGAGAAAAGTGGACCAGGCATGTCTTTTGCTTTGATCTGGAGGGAGGGCTGCCTGATGCAGGCC
GGCTCCCAGTGGGGCAGGCCTCGCTGCAGAATGCCCAGTAGTACTGCGGCCAAGGGGACAGTTAGGAGACTTCATCTAAAGCATGAAACC
TAGCTCCTCTACACACAAATTCCTATGGAAATACCTTTGTGTACAGTGTCTTACATTTTCCTATTAGTCAGAAAGAAGGAGAGAATGAGT
GAGTGCTTGAAATGTGTCATACTGTTTTAGGATCAAGACTAGGAATTAGGAGCCAGGTTGACAAGGACTTTTTCTGAGAGTTGGGTGAGG
GTAAAGCTTTTCTATAATCAAGCTCAATACACCAAGGAAACTGGATCCAGAATTCCTAAACTTTAAAATGGTACTGTCTGCGGAGTGGAG
TATGGATGGTTATGTCAAAGTCATAGTTCATCCTATCCAGATGTAGCATTCATGGTAAACTTTTAAGTGCTAAGCAAGGAATTATTTACT
GATTGGTTTTAAAGAGAGCAGAAAACACCCAAGTGTAGAATGTCTACTGTTTGCTACCTAGAAATCTTTTCCATTCCTCTTTCATACATT
CCAACCCACTGGAAGTCTTTAGAGGTATTTTGATTTAAAGTATACTTAAATTAGGATTTCTTAAAGAAAACATAGGGAGAAAACTTTACA
TGCAATTAAAAATGGACTTTCCTGTGATTTGTTTTTAATCATTCATTTGGAGAAGAGGCATGACCTTTGTATTTCACTAAGTTTAAAGCA
AGAGCAACTGATGATTAAATGTTGCTTTTTAATAAGGTTTTTAACTTGAAAATTTGAAAATATTTAATGTTGAAAGACTTCAATTAGGGC
TATTAGAGTTATATCTCCCTGTCGTAGGCAGCTTCTTCGGAGAAGTGAAATATAACATTACTCAGTGGACGGAGAAATCTGTTTTGTTAC
AGAGACATGCCTCTCAGAAGGTCAGGAGGTTTTGAGTACCTATCCTTGCCACCCATACAGGAAATCCAAAGTTTGGTGTCTCTCTCTCTC
TGTCTCTTTCTTTCTCTTTCTCCCCCCAAACCCCTCTCACTCCCTCCCTCCCTCTCTCCTTCCCCTATTTGCAATCATATTCTCCCTCTG
CTTCTTTTCTCTTCTGCCCTCCTTGTGGGCAGTCATGAAAATCAATTCAGACTGTGTTGATTAGCAGATTTATTATTCTATTGAGAAAGC
ACTGGAATGTTTTGTGAGATTATTTTTATATGAAGGAATAGCCTGAACTCAAACAGATGGTAAGAATAGTACAAACACCTTAGCACATCA
CTGCACACACAGTATTCTGAAAGGAGATTTGACACTTAATTCCCATTTTCTTAAAATAACAGTTTTGTTGACTTAAAAATATGAGATACA
TAGGATGTGAAAAAAAATGTTTGCAGTACTCAGCAAAAAATAGGGTACATAAAGCAGGGTGGCTGTCCATCCACTGATTCTGGGGTGAGA
AGCGATTTCTACCTCGCAAGAGTGACTAGAAAGTTTCTAGGAGCACCTCCAGGCTTGCAAAGAAAGTGAGGCCTCTTGGTATCCTTTCCT
CAGTGTGTATATGACAGCCAGTATAATCAATACCCTAGGTTATGCGTCTATATGATACTCATCTGTGAATATTATTGGTTTTGTAATCTT
TGTTATATAAGAGGATGTTTAGGCTGTATATACTGGGGTAGATTATTGCCTGCCCCTTATACATAGGAATATGCTGCATAATTGCGCATA
ACTTCCATCTCCCTTACTGGCTTGTAGGCAGAGGAAACTGTATATGTTACTGCCTTGTACTTTTCTCATACACCAAAAACACACCAAAAA
AATCAATAAAATAAGCAATCTTCTATTCTCATTCCTTTTCCCACAGCAGCATATTTTAGAGGCACATACAAAACCTACATTCTCTAGTTG
GGAGTGGATTTTTAAAGTTTTCCTTTTATCTTTTATTTTTTTTTGTATGATGCACTGAGATGTGTACTTTCTAACAGGGGATTGGTACCT
AAGAAATGTGGTAGCATTATTCAGAAAACTATTATACTTTCAAATGACACATAGTAAGGAGAATGGAATAATACATGTTGCATATTTGTT
ACCAGTTGTAATTTGTCTGTATTATGAAAGATGTAATGGTTTGTCAGCTGTCACTGTTGTTTTCTTGTAACATGATATGGAATAAAGTAT
AGCAGAATCTCCGTA

>35293_35293_5_GTPBP10-CDK14_GTPBP10_chr7_89976088_ENST00000257659_CDK14_chr7_90376996_ENST00000380050_length(amino acids)=375AA_BP=1
MYCGLCRFRKKVSWPVAAMVHCSCVLFRKPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASL
LKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLAD
FGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLP
HFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQPEAGESMRAF
GKNNSYGKSLSNSKH

--------------------------------------------------------------
>35293_35293_6_GTPBP10-CDK14_GTPBP10_chr7_89976088_ENST00000257659_CDK14_chr7_90376996_ENST00000406263_length(transcript)=4600nt_BP=110nt
GGGGATGACGTAAAAAGGCCGCGCTGTACTGCGGCTTGTGCCGCTTCCGCAAGAAGGTTTCCTGGCCTGTTGCAGCCATGGTGCATTGCA
GTTGCGTGTTGTTCAGAAAGCCAACAAGTCCCAAATTTGGAAAAGCTGACTCATATGAAAAGCTGGAAAAACTAGGGGAAGGATCTTATG
CTACAGTATACAAAGGGAAAAGCAAGGTAAATGGGAAGTTGGTAGCTCTGAAGGTGATCAGGCTGCAGGAAGAAGAAGGGACACCTTTCA
CAGCTATCAGGGAAGCTTCTCTTTTAAAAGGACTAAAACATGCTAACATAGTGCTACTTCATGACATCATCCATACCAAGGAGACGCTGA
CACTTGTGTTTGAATATGTGCACACTGATTTATGTCAGTACATGGACAAGCACCCTGGGGGGCTGCATCCAGATAATGTGAAGTTGTTTT
TATTTCAGTTGCTGCGAGGTCTGTCTTACATCCACCAGCGTTATATTTTGCACAGAGACCTGAAACCACAGAACCTTCTGATCAGTGACA
CGGGGGAGTTAAAGCTGGCAGATTTCGGTCTTGCAAGAGCAAAATCCGTCCCTAGCCACACATACTCCAACGAAGTGGTTACCTTGTGGT
ACAGACCTCCAGATGTCCTTCTAGGCTCAACAGAATATTCCACCTGCCTTGACATGTGGGGAGTAGGTTGCATCTTTGTTGAAATGATCC
AAGGAGTTGCTGCTTTTCCAGGAATGAAAGACATTCAGGATCAACTTGAACGAATATTTCTGGTTCTTGGAACACCAAATGAGGACACAT
GGCCTGGAGTTCATTCTTTACCACATTTTAAGCCAGAACGCTTTACCCTGTACAGCTCTAAAAACCTTAGACAAGCATGGAATAAGCTCA
GCTATGTGAACCATGCAGAGGACCTGGCCTCCAAGCTCCTACAATGTTCCCCAAAGAACAGACTGTCGGCACAGGCTGCCTTGAGCCACG
AGTATTTTAGTGACCTGCCGCCACGGCTATGGGAACTCACCGACATGTCTTCTATTTTTACTGTCCCAAATGTGAGATTGCAACCAGAAG
CTGGAGAAAGCATGCGGGCCTTTGGGAAAAACAATAGTTATGGCAAAAGTCTATCAAACAGCAAGCACTGACAAGCAGCACATTCTCAAG
AGCACACAGGATTAAGTTGTCATCATTCTGGGAAGAAAAAAAAAACATTAATGAAGAGGCCAATAATATGAAGGGAATCATGGATCAGTT
TTCTTTCGCTCCCTGTGGTGGATTTCACTTACAAGAAAATTGAAGCTGGCAAGACCCTGTTTTCTCTGCAATTTATTTAAAACCTTGCAC
GCATTTGGATACCTTGTGATTTCCAAGAACTACGTGAAGATTAAGCTTTGCTTACTGATACATGGCATGTATTCTTTTCAGTCTTTTGTG
TTTGATTTTGTTTGATTTCCCTCTGCAGCACAGCGTCTCTGTAAAGGTTTTTATGCTTTCACCAGCCATGTCTTAAATACATTAAGACAA
CACATTTGGTGTTCACACTTCTTCAGTAATGTCTGAACTTGAAAGCCACAGAGTGGCATAAAACAATGTGTGTTTTCTTTGAGAGCAGTG
CACATTTTGCAACCACTAGGAAGGAAATTTTCTGCTAAAGCAAACCCCTGTTCTCTGACTTGACAACTTGGCCCCGGACTGTGGGGCCCC
ACCTGTTGCTTACCTTTTGAGGTAATTTTGCAAATGTGGTTTTTTTACTTGGAAATAACTGCACATTTATATATAGGATATTGGACTCTG
CTTAGCATTTTCAAGCCACATAGCATGACTGTTTTTTGAATAGGTTGGAATTGAAAAAACAATTATCAAACGTTAAGAACAAAGACAGGG
ATAAATTGCTTACATTTCAACCTCTGGAGATTGAGGTAACTTTTTGTGTCTGGGTCTTGTCAACATCTAATTTTTTTCCATCCATTCTGT
TACACTTTGTATTTTCTAACTGGAGAAAAGAGTGAGGAACAGAATGTTTTAAATCTGGTGCAAAAGAACTATATCTGCTGGATGAGCCTT
GAAAGCAGTCTTGGCCTGTTAGGGCTTACAAAGTAAATTACAAAGTGATCCAGTTCAAAGTTTGCTTAGTTACAACAAAGCACCTTTAAA
AAAAATACATTTTAAAAAAACATTCCAAGCCAATTGGAAGACATCATTGGGTTCTTACTTTAAGACATCTCCTGGAATAACTGTTCAAAT
GCAGGTTTTAGAAACAATGCAGGAATCTTGCTTTAAAGATGAAAAAGGGAATGGGCCAGCTTCCCTTACTCAAGGAGTTGAGGGACCTTG
GAGGATGAAGGCGAGTATGTGACACTGGAGAAAAGTGGACCAGGCATGTCTTTTGCTTTGATCTGGAGGGAGGGCTGCCTGATGCAGGCC
GGCTCCCAGTGGGGCAGGCCTCGCTGCAGAATGCCCAGTAGTACTGCGGCCAAGGGGACAGTTAGGAGACTTCATCTAAAGCATGAAACC
TAGCTCCTCTACACACAAATTCCTATGGAAATACCTTTGTGTACAGTGTCTTACATTTTCCTATTAGTCAGAAAGAAGGAGAGAATGAGT
GAGTGCTTGAAATGTGTCATACTGTTTTAGGATCAAGACTAGGAATTAGGAGCCAGGTTGACAAGGACTTTTTCTGAGAGTTGGGTGAGG
GTAAAGCTTTTCTATAATCAAGCTCAATACACCAAGGAAACTGGATCCAGAATTCCTAAACTTTAAAATGGTACTGTCTGCGGAGTGGAG
TATGGATGGTTATGTCAAAGTCATAGTTCATCCTATCCAGATGTAGCATTCATGGTAAACTTTTAAGTGCTAAGCAAGGAATTATTTACT
GATTGGTTTTAAAGAGAGCAGAAAACACCCAAGTGTAGAATGTCTACTGTTTGCTACCTAGAAATCTTTTCCATTCCTCTTTCATACATT
CCAACCCACTGGAAGTCTTTAGAGGTATTTTGATTTAAAGTATACTTAAATTAGGATTTCTTAAAGAAAACATAGGGAGAAAACTTTACA
TGCAATTAAAAATGGACTTTCCTGTGATTTGTTTTTAATCATTCATTTGGAGAAGAGGCATGACCTTTGTATTTCACTAAGTTTAAAGCA
AGAGCAACTGATGATTAAATGTTGCTTTTTAATAAGGTTTTTAACTTGAAAATTTGAAAATATTTAATGTTGAAAGACTTCAATTAGGGC
TATTAGAGTTATATCTCCCTGTCGTAGGCAGCTTCTTCGGAGAAGTGAAATATAACATTACTCAGTGGACGGAGAAATCTGTTTTGTTAC
AGAGACATGCCTCTCAGAAGGTCAGGAGGTTTTGAGTACCTATCCTTGCCACCCATACAGGAAATCCAAAGTTTGGTGTCTCTCTCTCTC
TGTCTCTTTCTTTCTCTTTCTCCCCCCAAACCCCTCTCACTCCCTCCCTCCCTCTCTCCTTCCCCTATTTGCAATCATATTCTCCCTCTG
CTTCTTTTCTCTTCTGCCCTCCTTGTGGGCAGTCATGAAAATCAATTCAGACTGTGTTGATTAGCAGATTTATTATTCTATTGAGAAAGC
ACTGGAATGTTTTGTGAGATTATTTTTATATGAAGGAATAGCCTGAACTCAAACAGATGGTAAGAATAGTACAAACACCTTAGCACATCA
CTGCACACACAGTATTCTGAAAGGAGATTTGACACTTAATTCCCATTTTCTTAAAATAACAGTTTTGTTGACTTAAAAATATGAGATACA
TAGGATGTGAAAAAAAATGTTTGCAGTACTCAGCAAAAAATAGGGTACATAAAGCAGGGTGGCTGTCCATCCACTGATTCTGGGGTGAGA
AGCGATTTCTACCTCGCAAGAGTGACTAGAAAGTTTCTAGGAGCACCTCCAGGCTTGCAAAGAAAGTGAGGCCTCTTGGTATCCTTTCCT
CAGTGTGTATATGACAGCCAGTATAATCAATACCCTAGGTTATGCGTCTATATGATACTCATCTGTGAATATTATTGGTTTTGTAATCTT
TGTTATATAAGAGGATGTTTAGGCTGTATATACTGGGGTAGATTATTGCCTGCCCCTTATACATAGGAATATGCTGCATAATTGCGCATA
ACTTCCATCTCCCTTACTGGCTTGTAGGCAGAGGAAACTGTATATGTTACTGCCTTGTACTTTTCTCATACACCAAAAACACACCAAAAA
AATCAATAAAATAAGCAATCTTCTATTCTCATTCCTTTTCCCACAGCAGCATATTTTAGAGGCACATACAAAACCTACATTCTCTAGTTG
GGAGTGGATTTTTAAAGTTTTCCTTTTATCTTTTATTTTTTTTTGTATGATGCACTGAGATGTGTACTTTCTAACAGGGGATTGGTACCT
AAGAAATGTGGTAGCATTATTCAGAAAACTATTATACTTTCAAATGACACATAGTAAGGAGAATGGAATAATACATGTTGCATATTTGTT
ACCAGTTGTAATTTGTCTGTATTATGAAAGATGTAATGGTTTGTCAGCTGTCACTGTTGTTTTCTTGTAACATGATATGGAATAAAGTAT
AGCAGAATCT

>35293_35293_6_GTPBP10-CDK14_GTPBP10_chr7_89976088_ENST00000257659_CDK14_chr7_90376996_ENST00000406263_length(amino acids)=375AA_BP=1
MYCGLCRFRKKVSWPVAAMVHCSCVLFRKPTSPKFGKADSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEEEGTPFTAIREASL
LKGLKHANIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYILHRDLKPQNLLISDTGELKLAD
FGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLP
HFKPERFTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPPRLWELTDMSSIFTVPNVRLQPEAGESMRAF
GKNNSYGKSLSNSKH

--------------------------------------------------------------

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Fusion Gene PPI Analysis for GTPBP10-CDK14


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for GTPBP10-CDK14


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for GTPBP10-CDK14


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneC2239176Liver carcinoma1CTD_human