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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ALDH4A1-CAPZB (FusionGDB2 ID:HG8659TG832)

Fusion Gene Summary for ALDH4A1-CAPZB

check button Fusion gene summary
Fusion gene informationFusion gene name: ALDH4A1-CAPZB
Fusion gene ID: hg8659tg832
HgeneTgene
Gene symbol

ALDH4A1

CAPZB

Gene ID

8659

832

Gene namealdehyde dehydrogenase 4 family member A1capping actin protein of muscle Z-line subunit beta
SynonymsALDH4|P5CD|P5CDhCAPB|CAPPB|CAPZ
Cytomap('ALDH4A1')('CAPZB')

1p36.13

1p36.13

Type of geneprotein-codingprotein-coding
Descriptiondelta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrialL-glutamate gamma-semialdehyde dehydrogenaseP5C dehydrogenasealdehyde dehydrogenase family 4 member A1epididymis secretory sperm binding proteinmitochondrial delta-1-pyrroline 5-carboxylate F-actin-capping protein subunit betacapZ betacapping actin protein of muscle Z-line beta subunitcapping protein (actin filament) muscle Z-line, betaepididymis secretory sperm binding protein
Modification date2020031320200320
UniProtAcc.

P47756

Ensembl transtripts involved in fusion geneENST00000290597, ENST00000375341, 
ENST00000538839, ENST00000454547, 
ENST00000538309, 
Fusion gene scores* DoF score2 X 2 X 2=823 X 15 X 8=2760
# samples 227
** MAII scorelog2(2/8*10)=1.32192809488736log2(27/2760*10)=-3.3536369546147
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ALDH4A1 [Title/Abstract] AND CAPZB [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointALDH4A1(19228956)-CAPZB(19712120), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ALDH4A1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across CAPZB (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-BR-A4QI-01AALDH4A1chr1

19228956

-CAPZBchr1

19712120

-


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Fusion Gene ORF analysis for ALDH4A1-CAPZB

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000290597ENST00000375144ALDH4A1chr1

19228956

-CAPZBchr1

19712120

-
5CDS-5UTRENST00000290597ENST00000482808ALDH4A1chr1

19228956

-CAPZBchr1

19712120

-
5CDS-5UTRENST00000375341ENST00000375144ALDH4A1chr1

19228956

-CAPZBchr1

19712120

-
5CDS-5UTRENST00000375341ENST00000482808ALDH4A1chr1

19228956

-CAPZBchr1

19712120

-
5CDS-5UTRENST00000538839ENST00000375144ALDH4A1chr1

19228956

-CAPZBchr1

19712120

-
5CDS-5UTRENST00000538839ENST00000482808ALDH4A1chr1

19228956

-CAPZBchr1

19712120

-
In-frameENST00000290597ENST00000264202ALDH4A1chr1

19228956

-CAPZBchr1

19712120

-
In-frameENST00000290597ENST00000264203ALDH4A1chr1

19228956

-CAPZBchr1

19712120

-
In-frameENST00000290597ENST00000375142ALDH4A1chr1

19228956

-CAPZBchr1

19712120

-
In-frameENST00000290597ENST00000401084ALDH4A1chr1

19228956

-CAPZBchr1

19712120

-
In-frameENST00000290597ENST00000433834ALDH4A1chr1

19228956

-CAPZBchr1

19712120

-
In-frameENST00000375341ENST00000264202ALDH4A1chr1

19228956

-CAPZBchr1

19712120

-
In-frameENST00000375341ENST00000264203ALDH4A1chr1

19228956

-CAPZBchr1

19712120

-
In-frameENST00000375341ENST00000375142ALDH4A1chr1

19228956

-CAPZBchr1

19712120

-
In-frameENST00000375341ENST00000401084ALDH4A1chr1

19228956

-CAPZBchr1

19712120

-
In-frameENST00000375341ENST00000433834ALDH4A1chr1

19228956

-CAPZBchr1

19712120

-
In-frameENST00000538839ENST00000264202ALDH4A1chr1

19228956

-CAPZBchr1

19712120

-
In-frameENST00000538839ENST00000264203ALDH4A1chr1

19228956

-CAPZBchr1

19712120

-
In-frameENST00000538839ENST00000375142ALDH4A1chr1

19228956

-CAPZBchr1

19712120

-
In-frameENST00000538839ENST00000401084ALDH4A1chr1

19228956

-CAPZBchr1

19712120

-
In-frameENST00000538839ENST00000433834ALDH4A1chr1

19228956

-CAPZBchr1

19712120

-
intron-3CDSENST00000454547ENST00000264202ALDH4A1chr1

19228956

-CAPZBchr1

19712120

-
intron-3CDSENST00000454547ENST00000264203ALDH4A1chr1

19228956

-CAPZBchr1

19712120

-
intron-3CDSENST00000454547ENST00000375142ALDH4A1chr1

19228956

-CAPZBchr1

19712120

-
intron-3CDSENST00000454547ENST00000401084ALDH4A1chr1

19228956

-CAPZBchr1

19712120

-
intron-3CDSENST00000454547ENST00000433834ALDH4A1chr1

19228956

-CAPZBchr1

19712120

-
intron-3CDSENST00000538309ENST00000264202ALDH4A1chr1

19228956

-CAPZBchr1

19712120

-
intron-3CDSENST00000538309ENST00000264203ALDH4A1chr1

19228956

-CAPZBchr1

19712120

-
intron-3CDSENST00000538309ENST00000375142ALDH4A1chr1

19228956

-CAPZBchr1

19712120

-
intron-3CDSENST00000538309ENST00000401084ALDH4A1chr1

19228956

-CAPZBchr1

19712120

-
intron-3CDSENST00000538309ENST00000433834ALDH4A1chr1

19228956

-CAPZBchr1

19712120

-
intron-5UTRENST00000454547ENST00000375144ALDH4A1chr1

19228956

-CAPZBchr1

19712120

-
intron-5UTRENST00000454547ENST00000482808ALDH4A1chr1

19228956

-CAPZBchr1

19712120

-
intron-5UTRENST00000538309ENST00000375144ALDH4A1chr1

19228956

-CAPZBchr1

19712120

-
intron-5UTRENST00000538309ENST00000482808ALDH4A1chr1

19228956

-CAPZBchr1

19712120

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000538839ALDH4A1chr119228956-ENST00000401084CAPZBchr119712120-15506752792246
ENST00000538839ALDH4A1chr119228956-ENST00000264203CAPZBchr119712120-14706752678208
ENST00000538839ALDH4A1chr119228956-ENST00000375142CAPZBchr119712120-16136752807251
ENST00000538839ALDH4A1chr119228956-ENST00000433834CAPZBchr119712120-9646752792246
ENST00000538839ALDH4A1chr119228956-ENST00000264202CAPZBchr119712120-8086752807252
ENST00000290597ALDH4A1chr119228956-ENST00000401084CAPZBchr119712120-15759277817246
ENST00000290597ALDH4A1chr119228956-ENST00000264203CAPZBchr119712120-14959277703208
ENST00000290597ALDH4A1chr119228956-ENST00000375142CAPZBchr119712120-16389277832251
ENST00000290597ALDH4A1chr119228956-ENST00000433834CAPZBchr119712120-9899277817246
ENST00000290597ALDH4A1chr119228956-ENST00000264202CAPZBchr119712120-8339277832252
ENST00000375341ALDH4A1chr119228956-ENST00000401084CAPZBchr119712120-18033201221045307
ENST00000375341ALDH4A1chr119228956-ENST00000264203CAPZBchr119712120-1723320122931269
ENST00000375341ALDH4A1chr119228956-ENST00000375142CAPZBchr119712120-18663201221060312
ENST00000375341ALDH4A1chr119228956-ENST00000433834CAPZBchr119712120-12173201221045307
ENST00000375341ALDH4A1chr119228956-ENST00000264202CAPZBchr119712120-10613201221060313

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000538839ENST00000401084ALDH4A1chr119228956-CAPZBchr119712120-0.0029988260.9970011
ENST00000538839ENST00000264203ALDH4A1chr119228956-CAPZBchr119712120-0.0169969070.9830031
ENST00000538839ENST00000375142ALDH4A1chr119228956-CAPZBchr119712120-0.0023918560.9976082
ENST00000538839ENST00000433834ALDH4A1chr119228956-CAPZBchr119712120-0.0023153820.9976846
ENST00000538839ENST00000264202ALDH4A1chr119228956-CAPZBchr119712120-0.0025928270.99740714
ENST00000290597ENST00000401084ALDH4A1chr119228956-CAPZBchr119712120-0.0031146640.99688536
ENST00000290597ENST00000264203ALDH4A1chr119228956-CAPZBchr119712120-0.015378960.98462105
ENST00000290597ENST00000375142ALDH4A1chr119228956-CAPZBchr119712120-0.0024440610.99755585
ENST00000290597ENST00000433834ALDH4A1chr119228956-CAPZBchr119712120-0.0026863510.9973137
ENST00000290597ENST00000264202ALDH4A1chr119228956-CAPZBchr119712120-0.0027176130.9972824
ENST00000375341ENST00000401084ALDH4A1chr119228956-CAPZBchr119712120-0.0034280010.996572
ENST00000375341ENST00000264203ALDH4A1chr119228956-CAPZBchr119712120-0.0182905030.98170954
ENST00000375341ENST00000375142ALDH4A1chr119228956-CAPZBchr119712120-0.002848070.99715185
ENST00000375341ENST00000433834ALDH4A1chr119228956-CAPZBchr119712120-0.0023876160.99761236
ENST00000375341ENST00000264202ALDH4A1chr119228956-CAPZBchr119712120-0.0027169390.9972831

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Fusion Genomic Features for ALDH4A1-CAPZB


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for ALDH4A1-CAPZB


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:19228956/chr1:19712120)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.CAPZB

P47756

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization. {ECO:0000269|PubMed:21834987}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneALDH4A1chr1:19228956chr1:19712120ENST00000290597-116286_29020673.0Nucleotide bindingNAD
HgeneALDH4A1chr1:19228956chr1:19712120ENST00000375341-115286_29020564.0Nucleotide bindingNAD
HgeneALDH4A1chr1:19228956chr1:19712120ENST00000538309-115286_2900504.0Nucleotide bindingNAD
HgeneALDH4A1chr1:19228956chr1:19712120ENST00000538839-114286_29020513.0Nucleotide bindingNAD


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Fusion Gene Sequence for ALDH4A1-CAPZB


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>3913_3913_1_ALDH4A1-CAPZB_ALDH4A1_chr1_19228956_ENST00000290597_CAPZB_chr1_19712120_ENST00000264202_length(transcript)=833nt_BP=92nt
TCCAGCGAACAGCCCCGCTTCTAACCCGAGATGCTGCTGCCGGCGCCCGCGCTCCGCCGCGCCCTGCTGTCCCGCCCCTGGACCGGGGCC
GGGTCCCCAGTCTATGTGAGGATCTCCTGTCTTCTGTTGACCAGCCACTGAAAATTGCCAGAGACAAGGTGGTGGGAAAGGATTACCTTT
TGTGTGACTACAACAGAGATGGGGACTCCTATAGGTCACCATGGAGTAACAAGTATGACCCTCCCTTGGAGGATGGGGCCATGCCGTCAG
CTCGGCTGAGAAAGCTGGAGGTGGAAGCCAACAATGCCTTTGACCAGTATCGAGACCTGTATTTTGAAGGTGGCGTCTCATCTGTCTACC
TCTGGGATCTGGATCATGGCTTTGCTGGAGTGATCCTCATAAAGAAGGCTGGAGATGGATCAAAGAAGATCAAAGGCTGCTGGGATTCCA
TCCACGTGGTAGAAGTGCAGGAGAAATCCAGCGGTCGCACCGCCCATTACAAGTTGACCTCCACGGTGATGCTGTGGCTGCAGACCAACA
AATCTGGCTCTGGCACCATGAACCTCGGAGGCAGCCTTACCAGACAGATGGAGAAGGATGAAACTGTGAGTGACTGCTCCCCACACATAG
CCAACATCGGGCGCCTGGTAGAGGACATGGAAAATAAAATCAGAAGTACGCTGAACGAGATCTACTTTGGAAAAACAAAGGATATCGTCA
ATGGGCTGAGATCTATTGATGCTATCCCTGACAACCAAAAGTTTAAGCAGTTGCAGAGGGAGCTCTCTCAAGTGCTGACCCAGCGCCAGA
TCTACATCCAGCCTGATAATTAA

>3913_3913_1_ALDH4A1-CAPZB_ALDH4A1_chr1_19228956_ENST00000290597_CAPZB_chr1_19712120_ENST00000264202_length(amino acids)=252AA_BP=5
MDRGRVPSLCEDLLSSVDQPLKIARDKVVGKDYLLCDYNRDGDSYRSPWSNKYDPPLEDGAMPSARLRKLEVEANNAFDQYRDLYFEGGV
SSVYLWDLDHGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEKSSGRTAHYKLTSTVMLWLQTNKSGSGTMNLGGSLTRQMEKDETVSDC
SPHIANIGRLVEDMENKIRSTLNEIYFGKTKDIVNGLRSIDAIPDNQKFKQLQRELSQVLTQRQIYIQPDNX

--------------------------------------------------------------
>3913_3913_2_ALDH4A1-CAPZB_ALDH4A1_chr1_19228956_ENST00000290597_CAPZB_chr1_19712120_ENST00000264203_length(transcript)=1495nt_BP=92nt
TCCAGCGAACAGCCCCGCTTCTAACCCGAGATGCTGCTGCCGGCGCCCGCGCTCCGCCGCGCCCTGCTGTCCCGCCCCTGGACCGGGGCC
GGGTCCCCAGTCTATGTGAGGATCTCCTGTCTTCTGTTGACCAGCCACTGAAAATTGCCAGAGACAAGGTGGTGGGAAAGGATTACCTTT
TGTGTGACTACAACAGAGATGGGGACTCCTATAGGTCACCATGGAGTAACAAGTATGACCCTCCCTTGGAGGATGGGGCCATGCCGTCAG
CTCGGCTGAGAAAGCTGGAGGTGGAAGCCAACAATGCCTTTGACCAGTATCGAGACCTGTATTTTGAAGGTGGCGTCTCATCTGTCTACC
TCTGGGATCTGGATCATGGCTTTGCTGGAGTGATCCTCATAAAGAAGGCTGGAGATGGATCAAAGAAGATCAAAGGCTGCTGGGATTCCA
TCCACGTGGTAGAAGTGCAGGAGAAATCCAGCGGTCGCACCGCCCATTACAAGTTGACCTCCACGGTGATGCTGTGGCTGCAGACCAACA
AATCTGGCTCTGGCACCATGAACCTCGGAGGCAGCCTTACCAGACAGATGGAGAAGGATGAAACTGTGAGTGACTGCTCCCCACACATAG
CCAACATCGGGCGCCTGGTAGAGGTCTGTGCAGACTTTTGCAGACAAATCAAAACAAGAAGCTCTGAAGAATGACCTGGTGGAGGCTTTG
AAGAGAAAGCAGCAATGCTAAACCTCTGTTTCATGCTAACCAGACACGCCGTGCACTCGTTAGATTCCTTTCTTAGAAAACTCGTTTTCT
GCTCCCTTCCCTCGTCCCTTCCCTCCCCGACAGGTCACATAACAGCTGCATCATTGACCGCACAGCGCCATCTCTCCCTGAGAATAAAGC
CGATAGCCACCCTCCTCCGGCTCCGAGCCTGCTTCTGCCACACCTCGCTCTCAGTTCTCTCCACATTTCCATAGAGACCGTGTGGTTTTT
GTTCACCCGGGCCCCCCGTCTTCCTCCCTGTCCCCCCATTTATAGGCATAAAATCCACTGTCTGCCAGCCTCCCTTCCCTCCCACCTTTT
TGGTACATTGGTGTAAAAAATGTAAAACAAAAAAATTTTATGAACTAACTGTGGTGTGTGAAAGAGAGAAGAAAAACTGGAAATCTTATT
CCGTGTGTGTTTGGGAGTTGCTTGGGGTTGGGGGTCGTGGGGACAGGGGACAGCTCTGGGAGCAGAGGTGGCCCTCGGTGCCGTCCTGCG
CAGACTCTCCCGTCCCACGGAGGCCGCGGGGTGGGGGCTGGGGGGGGTGCCGCCGACCGTTCCGCTCTTCCGGCCAGGTGCTTTTCTGTC
AATTTCTATGGAATGCAAAAGGAGGTTTTTGTTTTATTTTGTTTTTTTGTAAAGCTTAAGAAAAAAATCTACATCTTATACTTGAGCCTC
CATACTTAAAAAAAGAAAAGAAAAGAAATCAATAAAAAGAAACTGGGGCGCAGTT

>3913_3913_2_ALDH4A1-CAPZB_ALDH4A1_chr1_19228956_ENST00000290597_CAPZB_chr1_19712120_ENST00000264203_length(amino acids)=208AA_BP=5
MDRGRVPSLCEDLLSSVDQPLKIARDKVVGKDYLLCDYNRDGDSYRSPWSNKYDPPLEDGAMPSARLRKLEVEANNAFDQYRDLYFEGGV
SSVYLWDLDHGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEKSSGRTAHYKLTSTVMLWLQTNKSGSGTMNLGGSLTRQMEKDETVSDC
SPHIANIGRLVEVCADFCRQIKTRSSEE

--------------------------------------------------------------
>3913_3913_3_ALDH4A1-CAPZB_ALDH4A1_chr1_19228956_ENST00000290597_CAPZB_chr1_19712120_ENST00000375142_length(transcript)=1638nt_BP=92nt
TCCAGCGAACAGCCCCGCTTCTAACCCGAGATGCTGCTGCCGGCGCCCGCGCTCCGCCGCGCCCTGCTGTCCCGCCCCTGGACCGGGGCC
GGGTCCCCAGTCTATGTGAGGATCTCCTGTCTTCTGTTGACCAGCCACTGAAAATTGCCAGAGACAAGGTGGTGGGAAAGGATTACCTTT
TGTGTGACTACAACAGAGATGGGGACTCCTATAGGTCACCATGGAGTAACAAGTATGACCCTCCCTTGGAGGATGGGGCCATGCCGTCAG
CTCGGCTGAGAAAGCTGGAGGTGGAAGCCAACAATGCCTTTGACCAGTATCGAGACCTGTATTTTGAAGGTGGCGTCTCATCTGTCTACC
TCTGGGATCTGGATCATGGCTTTGCTGGAGTGATCCTCATAAAGAAGGCTGGAGATGGATCAAAGAAGATCAAAGGCTGCTGGGATTCCA
TCCACGTGGTAGAAGTGCAGGAGAAATCCAGCGGTCGCACCGCCCATTACAAGTTGACCTCCACGGTGATGCTGTGGCTGCAGACCAACA
AATCTGGCTCTGGCACCATGAACCTCGGAGGCAGCCTTACCAGACAGATGGAGAAGGATGAAACTGTGAGTGACTGCTCCCCACACATAG
CCAACATCGGGCGCCTGGTAGAGGACATGGAAAATAAAATCAGAAGTACGCTGAACGAGATCTACTTTGGAAAAACAAAGGATATCGTCA
ATGGGCTGAGATCTATTGATGCTATCCCTGACAACCAAAAGTTTAAGCAGTTGCAGAGGGAGCTCTCTCAAGTGCTGACCCAGCGCCAGA
TCTACATCCAGCCTGATAATTAAGCCGATCCAGGTCTGTGCAGACTTTTGCAGACAAATCAAAACAAGAAGCTCTGAAGAATGACCTGGT
GGAGGCTTTGAAGAGAAAGCAGCAATGCTAAACCTCTGTTTCATGCTAACCAGACACGCCGTGCACTCGTTAGATTCCTTTCTTAGAAAA
CTCGTTTTCTGCTCCCTTCCCTCGTCCCTTCCCTCCCCGACAGGTCACATAACAGCTGCATCATTGACCGCACAGCGCCATCTCTCCCTG
AGAATAAAGCCGATAGCCACCCTCCTCCGGCTCCGAGCCTGCTTCTGCCACACCTCGCTCTCAGTTCTCTCCACATTTCCATAGAGACCG
TGTGGTTTTTGTTCACCCGGGCCCCCCGTCTTCCTCCCTGTCCCCCCATTTATAGGCATAAAATCCACTGTCTGCCAGCCTCCCTTCCCT
CCCACCTTTTTGGTACATTGGTGTAAAAAATGTAAAACAAAAAAATTTTATGAACTAACTGTGGTGTGTGAAAGAGAGAAGAAAAACTGG
AAATCTTATTCCGTGTGTGTTTGGGAGTTGCTTGGGGTTGGGGGTCGTGGGGACAGGGGACAGCTCTGGGAGCAGAGGTGGCCCTCGGTG
CCGTCCTGCGCAGACTCTCCCGTCCCACGGAGGCCGCGGGGTGGGGGCTGGGGGGGGTGCCGCCGACCGTTCCGCTCTTCCGGCCAGGTG
CTTTTCTGTCAATTTCTATGGAATGCAAAAGGAGGTTTTTGTTTTATTTTGTTTTTTTGTAAAGCTTAAGAAAAAAATCTACATCTTATA
CTTGAGCCTCCATACTTA

>3913_3913_3_ALDH4A1-CAPZB_ALDH4A1_chr1_19228956_ENST00000290597_CAPZB_chr1_19712120_ENST00000375142_length(amino acids)=251AA_BP=5
MDRGRVPSLCEDLLSSVDQPLKIARDKVVGKDYLLCDYNRDGDSYRSPWSNKYDPPLEDGAMPSARLRKLEVEANNAFDQYRDLYFEGGV
SSVYLWDLDHGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEKSSGRTAHYKLTSTVMLWLQTNKSGSGTMNLGGSLTRQMEKDETVSDC
SPHIANIGRLVEDMENKIRSTLNEIYFGKTKDIVNGLRSIDAIPDNQKFKQLQRELSQVLTQRQIYIQPDN

--------------------------------------------------------------
>3913_3913_4_ALDH4A1-CAPZB_ALDH4A1_chr1_19228956_ENST00000290597_CAPZB_chr1_19712120_ENST00000401084_length(transcript)=1575nt_BP=92nt
TCCAGCGAACAGCCCCGCTTCTAACCCGAGATGCTGCTGCCGGCGCCCGCGCTCCGCCGCGCCCTGCTGTCCCGCCCCTGGACCGGGGCC
GGGTCCCCAGTCTATGTGAGGATCTCCTGTCTTCTGTTGACCAGCCACTGAAAATTGCCAGAGACAAGGTGGTGGGAAAGGATTACCTTT
TGTGTGACTACAACAGAGATGGGGACTCCTATAGGTCACCATGGAGTAACAAGTATGACCCTCCCTTGGAGGATGGGGCCATGCCGTCAG
CTCGGCTGAGAAAGCTGGAGGTGGAAGCCAACAATGCCTTTGACCAGTATCGAGACCTGTATTTTGAAGGTGGCGTCTCATCTGTCTACC
TCTGGGATCTGGATCATGGCTTTGCTGGAGTGATCCTCATAAAGAAGGCTGGAGATGGATCAAAGAAGATCAAAGGCTGCTGGGATTCCA
TCCACGTGGTAGAAGTGCAGGAGAAATCCAGCGGTCGCACCGCCCATTACAAGTTGACCTCCACGGTGATGCTGTGGCTGCAGACCAACA
AATCTGGCTCTGGCACCATGAACCTCGGAGGCAGCCTTACCAGACAGATGGAGAAGGATGAAACTGTGAGTGACTGCTCCCCACACATAG
CCAACATCGGGCGCCTGGTAGAGGACATGGAAAATAAAATCAGAAGTACGCTGAACGAGATCTACTTTGGAAAAACAAAGGATATCGTCA
ATGGGCTGAGGTCTGTGCAGACTTTTGCAGACAAATCAAAACAAGAAGCTCTGAAGAATGACCTGGTGGAGGCTTTGAAGAGAAAGCAGC
AATGCTAAACCTCTGTTTCATGCTAACCAGACACGCCGTGCACTCGTTAGATTCCTTTCTTAGAAAACTCGTTTTCTGCTCCCTTCCCTC
GTCCCTTCCCTCCCCGACAGGTCACATAACAGCTGCATCATTGACCGCACAGCGCCATCTCTCCCTGAGAATAAAGCCGATAGCCACCCT
CCTCCGGCTCCGAGCCTGCTTCTGCCACACCTCGCTCTCAGTTCTCTCCACATTTCCATAGAGACCGTGTGGTTTTTGTTCACCCGGGCC
CCCCGTCTTCCTCCCTGTCCCCCCATTTATAGGCATAAAATCCACTGTCTGCCAGCCTCCCTTCCCTCCCACCTTTTTGGTACATTGGTG
TAAAAAATGTAAAACAAAAAAATTTTATGAACTAACTGTGGTGTGTGAAAGAGAGAAGAAAAACTGGAAATCTTATTCCGTGTGTGTTTG
GGAGTTGCTTGGGGTTGGGGGTCGTGGGGACAGGGGACAGCTCTGGGAGCAGAGGTGGCCCTCGGTGCCGTCCTGCGCAGACTCTCCCGT
CCCACGGAGGCCGCGGGGTGGGGGCTGGGGGGGGTGCCGCCGACCGTTCCGCTCTTCCGGCCAGGTGCTTTTCTGTCAATTTCTATGGAA
TGCAAAAGGAGGTTTTTGTTTTATTTTGTTTTTTTGTAAAGCTTAAGAAAAAAATCTACATCTTATACTTGAGCCTCCATACTTAAAAAA
AGAAAAGAAAAGAAATCAATAAAAAGAAACTGGGGCGCAGTTAGC

>3913_3913_4_ALDH4A1-CAPZB_ALDH4A1_chr1_19228956_ENST00000290597_CAPZB_chr1_19712120_ENST00000401084_length(amino acids)=246AA_BP=5
MDRGRVPSLCEDLLSSVDQPLKIARDKVVGKDYLLCDYNRDGDSYRSPWSNKYDPPLEDGAMPSARLRKLEVEANNAFDQYRDLYFEGGV
SSVYLWDLDHGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEKSSGRTAHYKLTSTVMLWLQTNKSGSGTMNLGGSLTRQMEKDETVSDC
SPHIANIGRLVEDMENKIRSTLNEIYFGKTKDIVNGLRSVQTFADKSKQEALKNDLVEALKRKQQC

--------------------------------------------------------------
>3913_3913_5_ALDH4A1-CAPZB_ALDH4A1_chr1_19228956_ENST00000290597_CAPZB_chr1_19712120_ENST00000433834_length(transcript)=989nt_BP=92nt
TCCAGCGAACAGCCCCGCTTCTAACCCGAGATGCTGCTGCCGGCGCCCGCGCTCCGCCGCGCCCTGCTGTCCCGCCCCTGGACCGGGGCC
GGGTCCCCAGTCTATGTGAGGATCTCCTGTCTTCTGTTGACCAGCCACTGAAAATTGCCAGAGACAAGGTGGTGGGAAAGGATTACCTTT
TGTGTGACTACAACAGAGATGGGGACTCCTATAGGTCACCATGGAGTAACAAGTATGACCCTCCCTTGGAGGATGGGGCCATGCCGTCAG
CTCGGCTGAGAAAGCTGGAGGTGGAAGCCAACAATGCCTTTGACCAGTATCGAGACCTGTATTTTGAAGGTGGCGTCTCATCTGTCTACC
TCTGGGATCTGGATCATGGCTTTGCTGGAGTGATCCTCATAAAGAAGGCTGGAGATGGATCAAAGAAGATCAAAGGCTGCTGGGATTCCA
TCCACGTGGTAGAAGTGCAGGAGAAATCCAGCGGTCGCACCGCCCATTACAAGTTGACCTCCACGGTGATGCTGTGGCTGCAGACCAACA
AATCTGGCTCTGGCACCATGAACCTCGGAGGCAGCCTTACCAGACAGATGGAGAAGGATGAAACTGTGAGTGACTGCTCCCCACACATAG
CCAACATCGGGCGCCTGGTAGAGGACATGGAAAATAAAATCAGAAGTACGCTGAACGAGATCTACTTTGGAAAAACAAAGGATATCGTCA
ATGGGCTGAGGTCTGTGCAGACTTTTGCAGACAAATCAAAACAAGAAGCTCTGAAGAATGACCTGGTGGAGGCTTTGAAGAGAAAGCAGC
AATGCTAAACCTCTGTTTCATGCTAACCAGACACGCCGTGCACTCGTTAGATTCCTTTCTTAGAAAACTCGTTTTCTGCTCCCTTCCCTC
GTCCCTTCCCTCCCCGACAGGTCACATAACAGCTGCATCATTGACCGCACAGCGCCATCTCTCCCTGAGAATAAAGCCGATAGCCACCC

>3913_3913_5_ALDH4A1-CAPZB_ALDH4A1_chr1_19228956_ENST00000290597_CAPZB_chr1_19712120_ENST00000433834_length(amino acids)=246AA_BP=5
MDRGRVPSLCEDLLSSVDQPLKIARDKVVGKDYLLCDYNRDGDSYRSPWSNKYDPPLEDGAMPSARLRKLEVEANNAFDQYRDLYFEGGV
SSVYLWDLDHGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEKSSGRTAHYKLTSTVMLWLQTNKSGSGTMNLGGSLTRQMEKDETVSDC
SPHIANIGRLVEDMENKIRSTLNEIYFGKTKDIVNGLRSVQTFADKSKQEALKNDLVEALKRKQQC

--------------------------------------------------------------
>3913_3913_6_ALDH4A1-CAPZB_ALDH4A1_chr1_19228956_ENST00000375341_CAPZB_chr1_19712120_ENST00000264202_length(transcript)=1061nt_BP=320nt
GGGAAAACGCATGCATTTCAGGACTTCGCTTTCGGGTTCCCTTGTCCTGTGTTGTGTAATGCCCCCGTTATGGCACTAGAAATATTTTTT
ATTAGCCGAAGCTAAATATAGTGGGACTTTGGCTGATCCCGAGCTCGGAGGACAGCCGGGGTGATCCGTTTCCCCCCGAGGATCGAGGTG
GTGCGCTCTGGACGGGGTTGTGCATTCTCGCCGCGCCCGGGCGGACGATCCAGCGAACAGCCCCGCTTCTAACCCGAGATGCTGCTGCCG
GCGCCCGCGCTCCGCCGCGCCCTGCTGTCCCGCCCCTGGACCGGGGCCGGGTCCCCAGTCTATGTGAGGATCTCCTGTCTTCTGTTGACC
AGCCACTGAAAATTGCCAGAGACAAGGTGGTGGGAAAGGATTACCTTTTGTGTGACTACAACAGAGATGGGGACTCCTATAGGTCACCAT
GGAGTAACAAGTATGACCCTCCCTTGGAGGATGGGGCCATGCCGTCAGCTCGGCTGAGAAAGCTGGAGGTGGAAGCCAACAATGCCTTTG
ACCAGTATCGAGACCTGTATTTTGAAGGTGGCGTCTCATCTGTCTACCTCTGGGATCTGGATCATGGCTTTGCTGGAGTGATCCTCATAA
AGAAGGCTGGAGATGGATCAAAGAAGATCAAAGGCTGCTGGGATTCCATCCACGTGGTAGAAGTGCAGGAGAAATCCAGCGGTCGCACCG
CCCATTACAAGTTGACCTCCACGGTGATGCTGTGGCTGCAGACCAACAAATCTGGCTCTGGCACCATGAACCTCGGAGGCAGCCTTACCA
GACAGATGGAGAAGGATGAAACTGTGAGTGACTGCTCCCCACACATAGCCAACATCGGGCGCCTGGTAGAGGACATGGAAAATAAAATCA
GAAGTACGCTGAACGAGATCTACTTTGGAAAAACAAAGGATATCGTCAATGGGCTGAGATCTATTGATGCTATCCCTGACAACCAAAAGT
TTAAGCAGTTGCAGAGGGAGCTCTCTCAAGTGCTGACCCAGCGCCAGATCTACATCCAGCCTGATAATTAA

>3913_3913_6_ALDH4A1-CAPZB_ALDH4A1_chr1_19228956_ENST00000375341_CAPZB_chr1_19712120_ENST00000264202_length(amino acids)=313AA_BP=66
MIPSSEDSRGDPFPPEDRGGALWTGLCILAAPGRTIQRTAPLLTRDAAAGARAPPRPAVPPLDRGRVPSLCEDLLSSVDQPLKIARDKVV
GKDYLLCDYNRDGDSYRSPWSNKYDPPLEDGAMPSARLRKLEVEANNAFDQYRDLYFEGGVSSVYLWDLDHGFAGVILIKKAGDGSKKIK
GCWDSIHVVEVQEKSSGRTAHYKLTSTVMLWLQTNKSGSGTMNLGGSLTRQMEKDETVSDCSPHIANIGRLVEDMENKIRSTLNEIYFGK
TKDIVNGLRSIDAIPDNQKFKQLQRELSQVLTQRQIYIQPDNX

--------------------------------------------------------------
>3913_3913_7_ALDH4A1-CAPZB_ALDH4A1_chr1_19228956_ENST00000375341_CAPZB_chr1_19712120_ENST00000264203_length(transcript)=1723nt_BP=320nt
GGGAAAACGCATGCATTTCAGGACTTCGCTTTCGGGTTCCCTTGTCCTGTGTTGTGTAATGCCCCCGTTATGGCACTAGAAATATTTTTT
ATTAGCCGAAGCTAAATATAGTGGGACTTTGGCTGATCCCGAGCTCGGAGGACAGCCGGGGTGATCCGTTTCCCCCCGAGGATCGAGGTG
GTGCGCTCTGGACGGGGTTGTGCATTCTCGCCGCGCCCGGGCGGACGATCCAGCGAACAGCCCCGCTTCTAACCCGAGATGCTGCTGCCG
GCGCCCGCGCTCCGCCGCGCCCTGCTGTCCCGCCCCTGGACCGGGGCCGGGTCCCCAGTCTATGTGAGGATCTCCTGTCTTCTGTTGACC
AGCCACTGAAAATTGCCAGAGACAAGGTGGTGGGAAAGGATTACCTTTTGTGTGACTACAACAGAGATGGGGACTCCTATAGGTCACCAT
GGAGTAACAAGTATGACCCTCCCTTGGAGGATGGGGCCATGCCGTCAGCTCGGCTGAGAAAGCTGGAGGTGGAAGCCAACAATGCCTTTG
ACCAGTATCGAGACCTGTATTTTGAAGGTGGCGTCTCATCTGTCTACCTCTGGGATCTGGATCATGGCTTTGCTGGAGTGATCCTCATAA
AGAAGGCTGGAGATGGATCAAAGAAGATCAAAGGCTGCTGGGATTCCATCCACGTGGTAGAAGTGCAGGAGAAATCCAGCGGTCGCACCG
CCCATTACAAGTTGACCTCCACGGTGATGCTGTGGCTGCAGACCAACAAATCTGGCTCTGGCACCATGAACCTCGGAGGCAGCCTTACCA
GACAGATGGAGAAGGATGAAACTGTGAGTGACTGCTCCCCACACATAGCCAACATCGGGCGCCTGGTAGAGGTCTGTGCAGACTTTTGCA
GACAAATCAAAACAAGAAGCTCTGAAGAATGACCTGGTGGAGGCTTTGAAGAGAAAGCAGCAATGCTAAACCTCTGTTTCATGCTAACCA
GACACGCCGTGCACTCGTTAGATTCCTTTCTTAGAAAACTCGTTTTCTGCTCCCTTCCCTCGTCCCTTCCCTCCCCGACAGGTCACATAA
CAGCTGCATCATTGACCGCACAGCGCCATCTCTCCCTGAGAATAAAGCCGATAGCCACCCTCCTCCGGCTCCGAGCCTGCTTCTGCCACA
CCTCGCTCTCAGTTCTCTCCACATTTCCATAGAGACCGTGTGGTTTTTGTTCACCCGGGCCCCCCGTCTTCCTCCCTGTCCCCCCATTTA
TAGGCATAAAATCCACTGTCTGCCAGCCTCCCTTCCCTCCCACCTTTTTGGTACATTGGTGTAAAAAATGTAAAACAAAAAAATTTTATG
AACTAACTGTGGTGTGTGAAAGAGAGAAGAAAAACTGGAAATCTTATTCCGTGTGTGTTTGGGAGTTGCTTGGGGTTGGGGGTCGTGGGG
ACAGGGGACAGCTCTGGGAGCAGAGGTGGCCCTCGGTGCCGTCCTGCGCAGACTCTCCCGTCCCACGGAGGCCGCGGGGTGGGGGCTGGG
GGGGGTGCCGCCGACCGTTCCGCTCTTCCGGCCAGGTGCTTTTCTGTCAATTTCTATGGAATGCAAAAGGAGGTTTTTGTTTTATTTTGT
TTTTTTGTAAAGCTTAAGAAAAAAATCTACATCTTATACTTGAGCCTCCATACTTAAAAAAAGAAAAGAAAAGAAATCAATAAAAAGAAA
CTGGGGCGCAGTT

>3913_3913_7_ALDH4A1-CAPZB_ALDH4A1_chr1_19228956_ENST00000375341_CAPZB_chr1_19712120_ENST00000264203_length(amino acids)=269AA_BP=66
MIPSSEDSRGDPFPPEDRGGALWTGLCILAAPGRTIQRTAPLLTRDAAAGARAPPRPAVPPLDRGRVPSLCEDLLSSVDQPLKIARDKVV
GKDYLLCDYNRDGDSYRSPWSNKYDPPLEDGAMPSARLRKLEVEANNAFDQYRDLYFEGGVSSVYLWDLDHGFAGVILIKKAGDGSKKIK
GCWDSIHVVEVQEKSSGRTAHYKLTSTVMLWLQTNKSGSGTMNLGGSLTRQMEKDETVSDCSPHIANIGRLVEVCADFCRQIKTRSSEE

--------------------------------------------------------------
>3913_3913_8_ALDH4A1-CAPZB_ALDH4A1_chr1_19228956_ENST00000375341_CAPZB_chr1_19712120_ENST00000375142_length(transcript)=1866nt_BP=320nt
GGGAAAACGCATGCATTTCAGGACTTCGCTTTCGGGTTCCCTTGTCCTGTGTTGTGTAATGCCCCCGTTATGGCACTAGAAATATTTTTT
ATTAGCCGAAGCTAAATATAGTGGGACTTTGGCTGATCCCGAGCTCGGAGGACAGCCGGGGTGATCCGTTTCCCCCCGAGGATCGAGGTG
GTGCGCTCTGGACGGGGTTGTGCATTCTCGCCGCGCCCGGGCGGACGATCCAGCGAACAGCCCCGCTTCTAACCCGAGATGCTGCTGCCG
GCGCCCGCGCTCCGCCGCGCCCTGCTGTCCCGCCCCTGGACCGGGGCCGGGTCCCCAGTCTATGTGAGGATCTCCTGTCTTCTGTTGACC
AGCCACTGAAAATTGCCAGAGACAAGGTGGTGGGAAAGGATTACCTTTTGTGTGACTACAACAGAGATGGGGACTCCTATAGGTCACCAT
GGAGTAACAAGTATGACCCTCCCTTGGAGGATGGGGCCATGCCGTCAGCTCGGCTGAGAAAGCTGGAGGTGGAAGCCAACAATGCCTTTG
ACCAGTATCGAGACCTGTATTTTGAAGGTGGCGTCTCATCTGTCTACCTCTGGGATCTGGATCATGGCTTTGCTGGAGTGATCCTCATAA
AGAAGGCTGGAGATGGATCAAAGAAGATCAAAGGCTGCTGGGATTCCATCCACGTGGTAGAAGTGCAGGAGAAATCCAGCGGTCGCACCG
CCCATTACAAGTTGACCTCCACGGTGATGCTGTGGCTGCAGACCAACAAATCTGGCTCTGGCACCATGAACCTCGGAGGCAGCCTTACCA
GACAGATGGAGAAGGATGAAACTGTGAGTGACTGCTCCCCACACATAGCCAACATCGGGCGCCTGGTAGAGGACATGGAAAATAAAATCA
GAAGTACGCTGAACGAGATCTACTTTGGAAAAACAAAGGATATCGTCAATGGGCTGAGATCTATTGATGCTATCCCTGACAACCAAAAGT
TTAAGCAGTTGCAGAGGGAGCTCTCTCAAGTGCTGACCCAGCGCCAGATCTACATCCAGCCTGATAATTAAGCCGATCCAGGTCTGTGCA
GACTTTTGCAGACAAATCAAAACAAGAAGCTCTGAAGAATGACCTGGTGGAGGCTTTGAAGAGAAAGCAGCAATGCTAAACCTCTGTTTC
ATGCTAACCAGACACGCCGTGCACTCGTTAGATTCCTTTCTTAGAAAACTCGTTTTCTGCTCCCTTCCCTCGTCCCTTCCCTCCCCGACA
GGTCACATAACAGCTGCATCATTGACCGCACAGCGCCATCTCTCCCTGAGAATAAAGCCGATAGCCACCCTCCTCCGGCTCCGAGCCTGC
TTCTGCCACACCTCGCTCTCAGTTCTCTCCACATTTCCATAGAGACCGTGTGGTTTTTGTTCACCCGGGCCCCCCGTCTTCCTCCCTGTC
CCCCCATTTATAGGCATAAAATCCACTGTCTGCCAGCCTCCCTTCCCTCCCACCTTTTTGGTACATTGGTGTAAAAAATGTAAAACAAAA
AAATTTTATGAACTAACTGTGGTGTGTGAAAGAGAGAAGAAAAACTGGAAATCTTATTCCGTGTGTGTTTGGGAGTTGCTTGGGGTTGGG
GGTCGTGGGGACAGGGGACAGCTCTGGGAGCAGAGGTGGCCCTCGGTGCCGTCCTGCGCAGACTCTCCCGTCCCACGGAGGCCGCGGGGT
GGGGGCTGGGGGGGGTGCCGCCGACCGTTCCGCTCTTCCGGCCAGGTGCTTTTCTGTCAATTTCTATGGAATGCAAAAGGAGGTTTTTGT
TTTATTTTGTTTTTTTGTAAAGCTTAAGAAAAAAATCTACATCTTATACTTGAGCCTCCATACTTA

>3913_3913_8_ALDH4A1-CAPZB_ALDH4A1_chr1_19228956_ENST00000375341_CAPZB_chr1_19712120_ENST00000375142_length(amino acids)=312AA_BP=66
MIPSSEDSRGDPFPPEDRGGALWTGLCILAAPGRTIQRTAPLLTRDAAAGARAPPRPAVPPLDRGRVPSLCEDLLSSVDQPLKIARDKVV
GKDYLLCDYNRDGDSYRSPWSNKYDPPLEDGAMPSARLRKLEVEANNAFDQYRDLYFEGGVSSVYLWDLDHGFAGVILIKKAGDGSKKIK
GCWDSIHVVEVQEKSSGRTAHYKLTSTVMLWLQTNKSGSGTMNLGGSLTRQMEKDETVSDCSPHIANIGRLVEDMENKIRSTLNEIYFGK
TKDIVNGLRSIDAIPDNQKFKQLQRELSQVLTQRQIYIQPDN

--------------------------------------------------------------
>3913_3913_9_ALDH4A1-CAPZB_ALDH4A1_chr1_19228956_ENST00000375341_CAPZB_chr1_19712120_ENST00000401084_length(transcript)=1803nt_BP=320nt
GGGAAAACGCATGCATTTCAGGACTTCGCTTTCGGGTTCCCTTGTCCTGTGTTGTGTAATGCCCCCGTTATGGCACTAGAAATATTTTTT
ATTAGCCGAAGCTAAATATAGTGGGACTTTGGCTGATCCCGAGCTCGGAGGACAGCCGGGGTGATCCGTTTCCCCCCGAGGATCGAGGTG
GTGCGCTCTGGACGGGGTTGTGCATTCTCGCCGCGCCCGGGCGGACGATCCAGCGAACAGCCCCGCTTCTAACCCGAGATGCTGCTGCCG
GCGCCCGCGCTCCGCCGCGCCCTGCTGTCCCGCCCCTGGACCGGGGCCGGGTCCCCAGTCTATGTGAGGATCTCCTGTCTTCTGTTGACC
AGCCACTGAAAATTGCCAGAGACAAGGTGGTGGGAAAGGATTACCTTTTGTGTGACTACAACAGAGATGGGGACTCCTATAGGTCACCAT
GGAGTAACAAGTATGACCCTCCCTTGGAGGATGGGGCCATGCCGTCAGCTCGGCTGAGAAAGCTGGAGGTGGAAGCCAACAATGCCTTTG
ACCAGTATCGAGACCTGTATTTTGAAGGTGGCGTCTCATCTGTCTACCTCTGGGATCTGGATCATGGCTTTGCTGGAGTGATCCTCATAA
AGAAGGCTGGAGATGGATCAAAGAAGATCAAAGGCTGCTGGGATTCCATCCACGTGGTAGAAGTGCAGGAGAAATCCAGCGGTCGCACCG
CCCATTACAAGTTGACCTCCACGGTGATGCTGTGGCTGCAGACCAACAAATCTGGCTCTGGCACCATGAACCTCGGAGGCAGCCTTACCA
GACAGATGGAGAAGGATGAAACTGTGAGTGACTGCTCCCCACACATAGCCAACATCGGGCGCCTGGTAGAGGACATGGAAAATAAAATCA
GAAGTACGCTGAACGAGATCTACTTTGGAAAAACAAAGGATATCGTCAATGGGCTGAGGTCTGTGCAGACTTTTGCAGACAAATCAAAAC
AAGAAGCTCTGAAGAATGACCTGGTGGAGGCTTTGAAGAGAAAGCAGCAATGCTAAACCTCTGTTTCATGCTAACCAGACACGCCGTGCA
CTCGTTAGATTCCTTTCTTAGAAAACTCGTTTTCTGCTCCCTTCCCTCGTCCCTTCCCTCCCCGACAGGTCACATAACAGCTGCATCATT
GACCGCACAGCGCCATCTCTCCCTGAGAATAAAGCCGATAGCCACCCTCCTCCGGCTCCGAGCCTGCTTCTGCCACACCTCGCTCTCAGT
TCTCTCCACATTTCCATAGAGACCGTGTGGTTTTTGTTCACCCGGGCCCCCCGTCTTCCTCCCTGTCCCCCCATTTATAGGCATAAAATC
CACTGTCTGCCAGCCTCCCTTCCCTCCCACCTTTTTGGTACATTGGTGTAAAAAATGTAAAACAAAAAAATTTTATGAACTAACTGTGGT
GTGTGAAAGAGAGAAGAAAAACTGGAAATCTTATTCCGTGTGTGTTTGGGAGTTGCTTGGGGTTGGGGGTCGTGGGGACAGGGGACAGCT
CTGGGAGCAGAGGTGGCCCTCGGTGCCGTCCTGCGCAGACTCTCCCGTCCCACGGAGGCCGCGGGGTGGGGGCTGGGGGGGGTGCCGCCG
ACCGTTCCGCTCTTCCGGCCAGGTGCTTTTCTGTCAATTTCTATGGAATGCAAAAGGAGGTTTTTGTTTTATTTTGTTTTTTTGTAAAGC
TTAAGAAAAAAATCTACATCTTATACTTGAGCCTCCATACTTAAAAAAAGAAAAGAAAAGAAATCAATAAAAAGAAACTGGGGCGCAGTT
AGC

>3913_3913_9_ALDH4A1-CAPZB_ALDH4A1_chr1_19228956_ENST00000375341_CAPZB_chr1_19712120_ENST00000401084_length(amino acids)=307AA_BP=66
MIPSSEDSRGDPFPPEDRGGALWTGLCILAAPGRTIQRTAPLLTRDAAAGARAPPRPAVPPLDRGRVPSLCEDLLSSVDQPLKIARDKVV
GKDYLLCDYNRDGDSYRSPWSNKYDPPLEDGAMPSARLRKLEVEANNAFDQYRDLYFEGGVSSVYLWDLDHGFAGVILIKKAGDGSKKIK
GCWDSIHVVEVQEKSSGRTAHYKLTSTVMLWLQTNKSGSGTMNLGGSLTRQMEKDETVSDCSPHIANIGRLVEDMENKIRSTLNEIYFGK
TKDIVNGLRSVQTFADKSKQEALKNDLVEALKRKQQC

--------------------------------------------------------------
>3913_3913_10_ALDH4A1-CAPZB_ALDH4A1_chr1_19228956_ENST00000375341_CAPZB_chr1_19712120_ENST00000433834_length(transcript)=1217nt_BP=320nt
GGGAAAACGCATGCATTTCAGGACTTCGCTTTCGGGTTCCCTTGTCCTGTGTTGTGTAATGCCCCCGTTATGGCACTAGAAATATTTTTT
ATTAGCCGAAGCTAAATATAGTGGGACTTTGGCTGATCCCGAGCTCGGAGGACAGCCGGGGTGATCCGTTTCCCCCCGAGGATCGAGGTG
GTGCGCTCTGGACGGGGTTGTGCATTCTCGCCGCGCCCGGGCGGACGATCCAGCGAACAGCCCCGCTTCTAACCCGAGATGCTGCTGCCG
GCGCCCGCGCTCCGCCGCGCCCTGCTGTCCCGCCCCTGGACCGGGGCCGGGTCCCCAGTCTATGTGAGGATCTCCTGTCTTCTGTTGACC
AGCCACTGAAAATTGCCAGAGACAAGGTGGTGGGAAAGGATTACCTTTTGTGTGACTACAACAGAGATGGGGACTCCTATAGGTCACCAT
GGAGTAACAAGTATGACCCTCCCTTGGAGGATGGGGCCATGCCGTCAGCTCGGCTGAGAAAGCTGGAGGTGGAAGCCAACAATGCCTTTG
ACCAGTATCGAGACCTGTATTTTGAAGGTGGCGTCTCATCTGTCTACCTCTGGGATCTGGATCATGGCTTTGCTGGAGTGATCCTCATAA
AGAAGGCTGGAGATGGATCAAAGAAGATCAAAGGCTGCTGGGATTCCATCCACGTGGTAGAAGTGCAGGAGAAATCCAGCGGTCGCACCG
CCCATTACAAGTTGACCTCCACGGTGATGCTGTGGCTGCAGACCAACAAATCTGGCTCTGGCACCATGAACCTCGGAGGCAGCCTTACCA
GACAGATGGAGAAGGATGAAACTGTGAGTGACTGCTCCCCACACATAGCCAACATCGGGCGCCTGGTAGAGGACATGGAAAATAAAATCA
GAAGTACGCTGAACGAGATCTACTTTGGAAAAACAAAGGATATCGTCAATGGGCTGAGGTCTGTGCAGACTTTTGCAGACAAATCAAAAC
AAGAAGCTCTGAAGAATGACCTGGTGGAGGCTTTGAAGAGAAAGCAGCAATGCTAAACCTCTGTTTCATGCTAACCAGACACGCCGTGCA
CTCGTTAGATTCCTTTCTTAGAAAACTCGTTTTCTGCTCCCTTCCCTCGTCCCTTCCCTCCCCGACAGGTCACATAACAGCTGCATCATT
GACCGCACAGCGCCATCTCTCCCTGAGAATAAAGCCGATAGCCACCC

>3913_3913_10_ALDH4A1-CAPZB_ALDH4A1_chr1_19228956_ENST00000375341_CAPZB_chr1_19712120_ENST00000433834_length(amino acids)=307AA_BP=66
MIPSSEDSRGDPFPPEDRGGALWTGLCILAAPGRTIQRTAPLLTRDAAAGARAPPRPAVPPLDRGRVPSLCEDLLSSVDQPLKIARDKVV
GKDYLLCDYNRDGDSYRSPWSNKYDPPLEDGAMPSARLRKLEVEANNAFDQYRDLYFEGGVSSVYLWDLDHGFAGVILIKKAGDGSKKIK
GCWDSIHVVEVQEKSSGRTAHYKLTSTVMLWLQTNKSGSGTMNLGGSLTRQMEKDETVSDCSPHIANIGRLVEDMENKIRSTLNEIYFGK
TKDIVNGLRSVQTFADKSKQEALKNDLVEALKRKQQC

--------------------------------------------------------------
>3913_3913_11_ALDH4A1-CAPZB_ALDH4A1_chr1_19228956_ENST00000538839_CAPZB_chr1_19712120_ENST00000264202_length(transcript)=808nt_BP=67nt
CCGAGATGCTGCTGCCGGCGCCCGCGCTCCGCCGCGCCCTGCTGTCCCGCCCCTGGACCGGGGCCGGGTCCCCAGTCTATGTGAGGATCT
CCTGTCTTCTGTTGACCAGCCACTGAAAATTGCCAGAGACAAGGTGGTGGGAAAGGATTACCTTTTGTGTGACTACAACAGAGATGGGGA
CTCCTATAGGTCACCATGGAGTAACAAGTATGACCCTCCCTTGGAGGATGGGGCCATGCCGTCAGCTCGGCTGAGAAAGCTGGAGGTGGA
AGCCAACAATGCCTTTGACCAGTATCGAGACCTGTATTTTGAAGGTGGCGTCTCATCTGTCTACCTCTGGGATCTGGATCATGGCTTTGC
TGGAGTGATCCTCATAAAGAAGGCTGGAGATGGATCAAAGAAGATCAAAGGCTGCTGGGATTCCATCCACGTGGTAGAAGTGCAGGAGAA
ATCCAGCGGTCGCACCGCCCATTACAAGTTGACCTCCACGGTGATGCTGTGGCTGCAGACCAACAAATCTGGCTCTGGCACCATGAACCT
CGGAGGCAGCCTTACCAGACAGATGGAGAAGGATGAAACTGTGAGTGACTGCTCCCCACACATAGCCAACATCGGGCGCCTGGTAGAGGA
CATGGAAAATAAAATCAGAAGTACGCTGAACGAGATCTACTTTGGAAAAACAAAGGATATCGTCAATGGGCTGAGATCTATTGATGCTAT
CCCTGACAACCAAAAGTTTAAGCAGTTGCAGAGGGAGCTCTCTCAAGTGCTGACCCAGCGCCAGATCTACATCCAGCCTGATAATTAA

>3913_3913_11_ALDH4A1-CAPZB_ALDH4A1_chr1_19228956_ENST00000538839_CAPZB_chr1_19712120_ENST00000264202_length(amino acids)=252AA_BP=5
MDRGRVPSLCEDLLSSVDQPLKIARDKVVGKDYLLCDYNRDGDSYRSPWSNKYDPPLEDGAMPSARLRKLEVEANNAFDQYRDLYFEGGV
SSVYLWDLDHGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEKSSGRTAHYKLTSTVMLWLQTNKSGSGTMNLGGSLTRQMEKDETVSDC
SPHIANIGRLVEDMENKIRSTLNEIYFGKTKDIVNGLRSIDAIPDNQKFKQLQRELSQVLTQRQIYIQPDNX

--------------------------------------------------------------
>3913_3913_12_ALDH4A1-CAPZB_ALDH4A1_chr1_19228956_ENST00000538839_CAPZB_chr1_19712120_ENST00000264203_length(transcript)=1470nt_BP=67nt
CCGAGATGCTGCTGCCGGCGCCCGCGCTCCGCCGCGCCCTGCTGTCCCGCCCCTGGACCGGGGCCGGGTCCCCAGTCTATGTGAGGATCT
CCTGTCTTCTGTTGACCAGCCACTGAAAATTGCCAGAGACAAGGTGGTGGGAAAGGATTACCTTTTGTGTGACTACAACAGAGATGGGGA
CTCCTATAGGTCACCATGGAGTAACAAGTATGACCCTCCCTTGGAGGATGGGGCCATGCCGTCAGCTCGGCTGAGAAAGCTGGAGGTGGA
AGCCAACAATGCCTTTGACCAGTATCGAGACCTGTATTTTGAAGGTGGCGTCTCATCTGTCTACCTCTGGGATCTGGATCATGGCTTTGC
TGGAGTGATCCTCATAAAGAAGGCTGGAGATGGATCAAAGAAGATCAAAGGCTGCTGGGATTCCATCCACGTGGTAGAAGTGCAGGAGAA
ATCCAGCGGTCGCACCGCCCATTACAAGTTGACCTCCACGGTGATGCTGTGGCTGCAGACCAACAAATCTGGCTCTGGCACCATGAACCT
CGGAGGCAGCCTTACCAGACAGATGGAGAAGGATGAAACTGTGAGTGACTGCTCCCCACACATAGCCAACATCGGGCGCCTGGTAGAGGT
CTGTGCAGACTTTTGCAGACAAATCAAAACAAGAAGCTCTGAAGAATGACCTGGTGGAGGCTTTGAAGAGAAAGCAGCAATGCTAAACCT
CTGTTTCATGCTAACCAGACACGCCGTGCACTCGTTAGATTCCTTTCTTAGAAAACTCGTTTTCTGCTCCCTTCCCTCGTCCCTTCCCTC
CCCGACAGGTCACATAACAGCTGCATCATTGACCGCACAGCGCCATCTCTCCCTGAGAATAAAGCCGATAGCCACCCTCCTCCGGCTCCG
AGCCTGCTTCTGCCACACCTCGCTCTCAGTTCTCTCCACATTTCCATAGAGACCGTGTGGTTTTTGTTCACCCGGGCCCCCCGTCTTCCT
CCCTGTCCCCCCATTTATAGGCATAAAATCCACTGTCTGCCAGCCTCCCTTCCCTCCCACCTTTTTGGTACATTGGTGTAAAAAATGTAA
AACAAAAAAATTTTATGAACTAACTGTGGTGTGTGAAAGAGAGAAGAAAAACTGGAAATCTTATTCCGTGTGTGTTTGGGAGTTGCTTGG
GGTTGGGGGTCGTGGGGACAGGGGACAGCTCTGGGAGCAGAGGTGGCCCTCGGTGCCGTCCTGCGCAGACTCTCCCGTCCCACGGAGGCC
GCGGGGTGGGGGCTGGGGGGGGTGCCGCCGACCGTTCCGCTCTTCCGGCCAGGTGCTTTTCTGTCAATTTCTATGGAATGCAAAAGGAGG
TTTTTGTTTTATTTTGTTTTTTTGTAAAGCTTAAGAAAAAAATCTACATCTTATACTTGAGCCTCCATACTTAAAAAAAGAAAAGAAAAG
AAATCAATAAAAAGAAACTGGGGCGCAGTT

>3913_3913_12_ALDH4A1-CAPZB_ALDH4A1_chr1_19228956_ENST00000538839_CAPZB_chr1_19712120_ENST00000264203_length(amino acids)=208AA_BP=5
MDRGRVPSLCEDLLSSVDQPLKIARDKVVGKDYLLCDYNRDGDSYRSPWSNKYDPPLEDGAMPSARLRKLEVEANNAFDQYRDLYFEGGV
SSVYLWDLDHGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEKSSGRTAHYKLTSTVMLWLQTNKSGSGTMNLGGSLTRQMEKDETVSDC
SPHIANIGRLVEVCADFCRQIKTRSSEE

--------------------------------------------------------------
>3913_3913_13_ALDH4A1-CAPZB_ALDH4A1_chr1_19228956_ENST00000538839_CAPZB_chr1_19712120_ENST00000375142_length(transcript)=1613nt_BP=67nt
CCGAGATGCTGCTGCCGGCGCCCGCGCTCCGCCGCGCCCTGCTGTCCCGCCCCTGGACCGGGGCCGGGTCCCCAGTCTATGTGAGGATCT
CCTGTCTTCTGTTGACCAGCCACTGAAAATTGCCAGAGACAAGGTGGTGGGAAAGGATTACCTTTTGTGTGACTACAACAGAGATGGGGA
CTCCTATAGGTCACCATGGAGTAACAAGTATGACCCTCCCTTGGAGGATGGGGCCATGCCGTCAGCTCGGCTGAGAAAGCTGGAGGTGGA
AGCCAACAATGCCTTTGACCAGTATCGAGACCTGTATTTTGAAGGTGGCGTCTCATCTGTCTACCTCTGGGATCTGGATCATGGCTTTGC
TGGAGTGATCCTCATAAAGAAGGCTGGAGATGGATCAAAGAAGATCAAAGGCTGCTGGGATTCCATCCACGTGGTAGAAGTGCAGGAGAA
ATCCAGCGGTCGCACCGCCCATTACAAGTTGACCTCCACGGTGATGCTGTGGCTGCAGACCAACAAATCTGGCTCTGGCACCATGAACCT
CGGAGGCAGCCTTACCAGACAGATGGAGAAGGATGAAACTGTGAGTGACTGCTCCCCACACATAGCCAACATCGGGCGCCTGGTAGAGGA
CATGGAAAATAAAATCAGAAGTACGCTGAACGAGATCTACTTTGGAAAAACAAAGGATATCGTCAATGGGCTGAGATCTATTGATGCTAT
CCCTGACAACCAAAAGTTTAAGCAGTTGCAGAGGGAGCTCTCTCAAGTGCTGACCCAGCGCCAGATCTACATCCAGCCTGATAATTAAGC
CGATCCAGGTCTGTGCAGACTTTTGCAGACAAATCAAAACAAGAAGCTCTGAAGAATGACCTGGTGGAGGCTTTGAAGAGAAAGCAGCAA
TGCTAAACCTCTGTTTCATGCTAACCAGACACGCCGTGCACTCGTTAGATTCCTTTCTTAGAAAACTCGTTTTCTGCTCCCTTCCCTCGT
CCCTTCCCTCCCCGACAGGTCACATAACAGCTGCATCATTGACCGCACAGCGCCATCTCTCCCTGAGAATAAAGCCGATAGCCACCCTCC
TCCGGCTCCGAGCCTGCTTCTGCCACACCTCGCTCTCAGTTCTCTCCACATTTCCATAGAGACCGTGTGGTTTTTGTTCACCCGGGCCCC
CCGTCTTCCTCCCTGTCCCCCCATTTATAGGCATAAAATCCACTGTCTGCCAGCCTCCCTTCCCTCCCACCTTTTTGGTACATTGGTGTA
AAAAATGTAAAACAAAAAAATTTTATGAACTAACTGTGGTGTGTGAAAGAGAGAAGAAAAACTGGAAATCTTATTCCGTGTGTGTTTGGG
AGTTGCTTGGGGTTGGGGGTCGTGGGGACAGGGGACAGCTCTGGGAGCAGAGGTGGCCCTCGGTGCCGTCCTGCGCAGACTCTCCCGTCC
CACGGAGGCCGCGGGGTGGGGGCTGGGGGGGGTGCCGCCGACCGTTCCGCTCTTCCGGCCAGGTGCTTTTCTGTCAATTTCTATGGAATG
CAAAAGGAGGTTTTTGTTTTATTTTGTTTTTTTGTAAAGCTTAAGAAAAAAATCTACATCTTATACTTGAGCCTCCATACTTA

>3913_3913_13_ALDH4A1-CAPZB_ALDH4A1_chr1_19228956_ENST00000538839_CAPZB_chr1_19712120_ENST00000375142_length(amino acids)=251AA_BP=5
MDRGRVPSLCEDLLSSVDQPLKIARDKVVGKDYLLCDYNRDGDSYRSPWSNKYDPPLEDGAMPSARLRKLEVEANNAFDQYRDLYFEGGV
SSVYLWDLDHGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEKSSGRTAHYKLTSTVMLWLQTNKSGSGTMNLGGSLTRQMEKDETVSDC
SPHIANIGRLVEDMENKIRSTLNEIYFGKTKDIVNGLRSIDAIPDNQKFKQLQRELSQVLTQRQIYIQPDN

--------------------------------------------------------------
>3913_3913_14_ALDH4A1-CAPZB_ALDH4A1_chr1_19228956_ENST00000538839_CAPZB_chr1_19712120_ENST00000401084_length(transcript)=1550nt_BP=67nt
CCGAGATGCTGCTGCCGGCGCCCGCGCTCCGCCGCGCCCTGCTGTCCCGCCCCTGGACCGGGGCCGGGTCCCCAGTCTATGTGAGGATCT
CCTGTCTTCTGTTGACCAGCCACTGAAAATTGCCAGAGACAAGGTGGTGGGAAAGGATTACCTTTTGTGTGACTACAACAGAGATGGGGA
CTCCTATAGGTCACCATGGAGTAACAAGTATGACCCTCCCTTGGAGGATGGGGCCATGCCGTCAGCTCGGCTGAGAAAGCTGGAGGTGGA
AGCCAACAATGCCTTTGACCAGTATCGAGACCTGTATTTTGAAGGTGGCGTCTCATCTGTCTACCTCTGGGATCTGGATCATGGCTTTGC
TGGAGTGATCCTCATAAAGAAGGCTGGAGATGGATCAAAGAAGATCAAAGGCTGCTGGGATTCCATCCACGTGGTAGAAGTGCAGGAGAA
ATCCAGCGGTCGCACCGCCCATTACAAGTTGACCTCCACGGTGATGCTGTGGCTGCAGACCAACAAATCTGGCTCTGGCACCATGAACCT
CGGAGGCAGCCTTACCAGACAGATGGAGAAGGATGAAACTGTGAGTGACTGCTCCCCACACATAGCCAACATCGGGCGCCTGGTAGAGGA
CATGGAAAATAAAATCAGAAGTACGCTGAACGAGATCTACTTTGGAAAAACAAAGGATATCGTCAATGGGCTGAGGTCTGTGCAGACTTT
TGCAGACAAATCAAAACAAGAAGCTCTGAAGAATGACCTGGTGGAGGCTTTGAAGAGAAAGCAGCAATGCTAAACCTCTGTTTCATGCTA
ACCAGACACGCCGTGCACTCGTTAGATTCCTTTCTTAGAAAACTCGTTTTCTGCTCCCTTCCCTCGTCCCTTCCCTCCCCGACAGGTCAC
ATAACAGCTGCATCATTGACCGCACAGCGCCATCTCTCCCTGAGAATAAAGCCGATAGCCACCCTCCTCCGGCTCCGAGCCTGCTTCTGC
CACACCTCGCTCTCAGTTCTCTCCACATTTCCATAGAGACCGTGTGGTTTTTGTTCACCCGGGCCCCCCGTCTTCCTCCCTGTCCCCCCA
TTTATAGGCATAAAATCCACTGTCTGCCAGCCTCCCTTCCCTCCCACCTTTTTGGTACATTGGTGTAAAAAATGTAAAACAAAAAAATTT
TATGAACTAACTGTGGTGTGTGAAAGAGAGAAGAAAAACTGGAAATCTTATTCCGTGTGTGTTTGGGAGTTGCTTGGGGTTGGGGGTCGT
GGGGACAGGGGACAGCTCTGGGAGCAGAGGTGGCCCTCGGTGCCGTCCTGCGCAGACTCTCCCGTCCCACGGAGGCCGCGGGGTGGGGGC
TGGGGGGGGTGCCGCCGACCGTTCCGCTCTTCCGGCCAGGTGCTTTTCTGTCAATTTCTATGGAATGCAAAAGGAGGTTTTTGTTTTATT
TTGTTTTTTTGTAAAGCTTAAGAAAAAAATCTACATCTTATACTTGAGCCTCCATACTTAAAAAAAGAAAAGAAAAGAAATCAATAAAAA
GAAACTGGGGCGCAGTTAGC

>3913_3913_14_ALDH4A1-CAPZB_ALDH4A1_chr1_19228956_ENST00000538839_CAPZB_chr1_19712120_ENST00000401084_length(amino acids)=246AA_BP=5
MDRGRVPSLCEDLLSSVDQPLKIARDKVVGKDYLLCDYNRDGDSYRSPWSNKYDPPLEDGAMPSARLRKLEVEANNAFDQYRDLYFEGGV
SSVYLWDLDHGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEKSSGRTAHYKLTSTVMLWLQTNKSGSGTMNLGGSLTRQMEKDETVSDC
SPHIANIGRLVEDMENKIRSTLNEIYFGKTKDIVNGLRSVQTFADKSKQEALKNDLVEALKRKQQC

--------------------------------------------------------------
>3913_3913_15_ALDH4A1-CAPZB_ALDH4A1_chr1_19228956_ENST00000538839_CAPZB_chr1_19712120_ENST00000433834_length(transcript)=964nt_BP=67nt
CCGAGATGCTGCTGCCGGCGCCCGCGCTCCGCCGCGCCCTGCTGTCCCGCCCCTGGACCGGGGCCGGGTCCCCAGTCTATGTGAGGATCT
CCTGTCTTCTGTTGACCAGCCACTGAAAATTGCCAGAGACAAGGTGGTGGGAAAGGATTACCTTTTGTGTGACTACAACAGAGATGGGGA
CTCCTATAGGTCACCATGGAGTAACAAGTATGACCCTCCCTTGGAGGATGGGGCCATGCCGTCAGCTCGGCTGAGAAAGCTGGAGGTGGA
AGCCAACAATGCCTTTGACCAGTATCGAGACCTGTATTTTGAAGGTGGCGTCTCATCTGTCTACCTCTGGGATCTGGATCATGGCTTTGC
TGGAGTGATCCTCATAAAGAAGGCTGGAGATGGATCAAAGAAGATCAAAGGCTGCTGGGATTCCATCCACGTGGTAGAAGTGCAGGAGAA
ATCCAGCGGTCGCACCGCCCATTACAAGTTGACCTCCACGGTGATGCTGTGGCTGCAGACCAACAAATCTGGCTCTGGCACCATGAACCT
CGGAGGCAGCCTTACCAGACAGATGGAGAAGGATGAAACTGTGAGTGACTGCTCCCCACACATAGCCAACATCGGGCGCCTGGTAGAGGA
CATGGAAAATAAAATCAGAAGTACGCTGAACGAGATCTACTTTGGAAAAACAAAGGATATCGTCAATGGGCTGAGGTCTGTGCAGACTTT
TGCAGACAAATCAAAACAAGAAGCTCTGAAGAATGACCTGGTGGAGGCTTTGAAGAGAAAGCAGCAATGCTAAACCTCTGTTTCATGCTA
ACCAGACACGCCGTGCACTCGTTAGATTCCTTTCTTAGAAAACTCGTTTTCTGCTCCCTTCCCTCGTCCCTTCCCTCCCCGACAGGTCAC
ATAACAGCTGCATCATTGACCGCACAGCGCCATCTCTCCCTGAGAATAAAGCCGATAGCCACCC

>3913_3913_15_ALDH4A1-CAPZB_ALDH4A1_chr1_19228956_ENST00000538839_CAPZB_chr1_19712120_ENST00000433834_length(amino acids)=246AA_BP=5
MDRGRVPSLCEDLLSSVDQPLKIARDKVVGKDYLLCDYNRDGDSYRSPWSNKYDPPLEDGAMPSARLRKLEVEANNAFDQYRDLYFEGGV
SSVYLWDLDHGFAGVILIKKAGDGSKKIKGCWDSIHVVEVQEKSSGRTAHYKLTSTVMLWLQTNKSGSGTMNLGGSLTRQMEKDETVSDC
SPHIANIGRLVEDMENKIRSTLNEIYFGKTKDIVNGLRSVQTFADKSKQEALKNDLVEALKRKQQC

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ALDH4A1-CAPZB


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ALDH4A1-CAPZB


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ALDH4A1-CAPZB


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneALDH4A1C2931835Hyperprolinemia type 26CLINGEN;CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
HgeneALDH4A1C0032927Precancerous Conditions1CTD_human
HgeneALDH4A1C0282313Condition, Preneoplastic1CTD_human
HgeneALDH4A1C0400966Non-alcoholic Fatty Liver Disease1CTD_human
HgeneALDH4A1C3241937Nonalcoholic Steatohepatitis1CTD_human
HgeneALDH4A1C3714756Intellectual Disability1GENOMICS_ENGLAND
TgeneC0007097Carcinoma1CTD_human
TgeneC0024667Animal Mammary Neoplasms1CTD_human
TgeneC0024668Mammary Neoplasms, Experimental1CTD_human
TgeneC0205696Anaplastic carcinoma1CTD_human
TgeneC0205697Carcinoma, Spindle-Cell1CTD_human
TgeneC0205698Undifferentiated carcinoma1CTD_human
TgeneC0205699Carcinomatosis1CTD_human
TgeneC0948089Acute Coronary Syndrome1CTD_human
TgeneC1257925Mammary Carcinoma, Animal1CTD_human