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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:ASH2L-CASS4 (FusionGDB2 ID:HG9070TG57091) |
Fusion Gene Summary for ASH2L-CASS4 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ASH2L-CASS4 | Fusion gene ID: hg9070tg57091 | Hgene | Tgene | Gene symbol | ASH2L | CASS4 | Gene ID | 9070 | 57091 |
| Gene name | ASH2 like, histone lysine methyltransferase complex subunit | Cas scaffold protein family member 4 | |
| Synonyms | ASH2|ASH2L1|ASH2L2|Bre2 | C20orf32|CAS4|HEFL|HEPL | |
| Cytomap | ('ASH2L')('CASS4') 8p11.23 | 20q13.31 | |
| Type of gene | protein-coding | protein-coding | |
| Description | set1/Ash2 histone methyltransferase complex subunit ASH2ASH2-like proteinash2 (absent, small, or homeotic)-like | cas scaffolding protein family member 4HEF-like proteinHEF1-EFS-p130Cas-like protein | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | . | . | |
| Ensembl transtripts involved in fusion gene | ENST00000250635, ENST00000343823, ENST00000428278, ENST00000521652, ENST00000545394, ENST00000524263, | ||
| Fusion gene scores | * DoF score | 13 X 10 X 6=780 | 7 X 5 X 4=140 |
| # samples | 14 | 8 | |
| ** MAII score | log2(14/780*10)=-2.47804729680464 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(8/140*10)=-0.807354922057604 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ASH2L [Title/Abstract] AND CASS4 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | ASH2L(37991064)-CASS4(55020956), # samples:3 | ||
| Anticipated loss of major functional domain due to fusion event. | ASH2L-CASS4 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. ASH2L-CASS4 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. ASH2L-CASS4 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. ASH2L-CASS4 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | ASH2L | GO:0006974 | cellular response to DNA damage stimulus | 17500065 |
| Hgene | ASH2L | GO:0043627 | response to estrogen | 16603732 |
| Hgene | ASH2L | GO:0051568 | histone H3-K4 methylation | 17355966|19556245 |
| Tgene | CASS4 | GO:0061098 | positive regulation of protein tyrosine kinase activity | 18256281 |
| Fusion gene breakpoints across ASH2L (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across CASS4 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | SARC | TCGA-DX-A3LS-01A | ASH2L | chr8 | 37991064 | - | CASS4 | chr20 | 55020956 | + |
| ChimerDB4 | SARC | TCGA-DX-A3LS-01A | ASH2L | chr8 | 37991064 | + | CASS4 | chr20 | 55020956 | + |
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Fusion Gene ORF analysis for ASH2L-CASS4 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000250635 | ENST00000360314 | ASH2L | chr8 | 37991064 | + | CASS4 | chr20 | 55020956 | + |
| In-frame | ENST00000250635 | ENST00000371336 | ASH2L | chr8 | 37991064 | + | CASS4 | chr20 | 55020956 | + |
| In-frame | ENST00000250635 | ENST00000434344 | ASH2L | chr8 | 37991064 | + | CASS4 | chr20 | 55020956 | + |
| In-frame | ENST00000343823 | ENST00000360314 | ASH2L | chr8 | 37991064 | + | CASS4 | chr20 | 55020956 | + |
| In-frame | ENST00000343823 | ENST00000371336 | ASH2L | chr8 | 37991064 | + | CASS4 | chr20 | 55020956 | + |
| In-frame | ENST00000343823 | ENST00000434344 | ASH2L | chr8 | 37991064 | + | CASS4 | chr20 | 55020956 | + |
| In-frame | ENST00000428278 | ENST00000360314 | ASH2L | chr8 | 37991064 | + | CASS4 | chr20 | 55020956 | + |
| In-frame | ENST00000428278 | ENST00000371336 | ASH2L | chr8 | 37991064 | + | CASS4 | chr20 | 55020956 | + |
| In-frame | ENST00000428278 | ENST00000434344 | ASH2L | chr8 | 37991064 | + | CASS4 | chr20 | 55020956 | + |
| In-frame | ENST00000521652 | ENST00000360314 | ASH2L | chr8 | 37991064 | + | CASS4 | chr20 | 55020956 | + |
| In-frame | ENST00000521652 | ENST00000371336 | ASH2L | chr8 | 37991064 | + | CASS4 | chr20 | 55020956 | + |
| In-frame | ENST00000521652 | ENST00000434344 | ASH2L | chr8 | 37991064 | + | CASS4 | chr20 | 55020956 | + |
| In-frame | ENST00000545394 | ENST00000360314 | ASH2L | chr8 | 37991064 | + | CASS4 | chr20 | 55020956 | + |
| In-frame | ENST00000545394 | ENST00000371336 | ASH2L | chr8 | 37991064 | + | CASS4 | chr20 | 55020956 | + |
| In-frame | ENST00000545394 | ENST00000434344 | ASH2L | chr8 | 37991064 | + | CASS4 | chr20 | 55020956 | + |
| intron-3CDS | ENST00000524263 | ENST00000360314 | ASH2L | chr8 | 37991064 | + | CASS4 | chr20 | 55020956 | + |
| intron-3CDS | ENST00000524263 | ENST00000371336 | ASH2L | chr8 | 37991064 | + | CASS4 | chr20 | 55020956 | + |
| intron-3CDS | ENST00000524263 | ENST00000434344 | ASH2L | chr8 | 37991064 | + | CASS4 | chr20 | 55020956 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000343823 | ASH2L | chr8 | 37991064 | + | ENST00000360314 | CASS4 | chr20 | 55020956 | + | 3864 | 1929 | 309 | 3830 | 1173 |
| ENST00000343823 | ASH2L | chr8 | 37991064 | + | ENST00000371336 | CASS4 | chr20 | 55020956 | + | 4424 | 1929 | 309 | 3830 | 1173 |
| ENST00000343823 | ASH2L | chr8 | 37991064 | + | ENST00000434344 | CASS4 | chr20 | 55020956 | + | 3112 | 1929 | 309 | 2519 | 736 |
| ENST00000250635 | ASH2L | chr8 | 37991064 | + | ENST00000360314 | CASS4 | chr20 | 55020956 | + | 3613 | 1678 | 58 | 3579 | 1173 |
| ENST00000250635 | ASH2L | chr8 | 37991064 | + | ENST00000371336 | CASS4 | chr20 | 55020956 | + | 4173 | 1678 | 58 | 3579 | 1173 |
| ENST00000250635 | ASH2L | chr8 | 37991064 | + | ENST00000434344 | CASS4 | chr20 | 55020956 | + | 2861 | 1678 | 58 | 2268 | 736 |
| ENST00000545394 | ASH2L | chr8 | 37991064 | + | ENST00000360314 | CASS4 | chr20 | 55020956 | + | 3410 | 1475 | 272 | 3376 | 1034 |
| ENST00000545394 | ASH2L | chr8 | 37991064 | + | ENST00000371336 | CASS4 | chr20 | 55020956 | + | 3970 | 1475 | 272 | 3376 | 1034 |
| ENST00000545394 | ASH2L | chr8 | 37991064 | + | ENST00000434344 | CASS4 | chr20 | 55020956 | + | 2658 | 1475 | 272 | 2065 | 597 |
| ENST00000428278 | ASH2L | chr8 | 37991064 | + | ENST00000360314 | CASS4 | chr20 | 55020956 | + | 3714 | 1779 | 357 | 3680 | 1107 |
| ENST00000428278 | ASH2L | chr8 | 37991064 | + | ENST00000371336 | CASS4 | chr20 | 55020956 | + | 4274 | 1779 | 357 | 3680 | 1107 |
| ENST00000428278 | ASH2L | chr8 | 37991064 | + | ENST00000434344 | CASS4 | chr20 | 55020956 | + | 2962 | 1779 | 357 | 2369 | 670 |
| ENST00000521652 | ASH2L | chr8 | 37991064 | + | ENST00000360314 | CASS4 | chr20 | 55020956 | + | 3568 | 1633 | 211 | 3534 | 1107 |
| ENST00000521652 | ASH2L | chr8 | 37991064 | + | ENST00000371336 | CASS4 | chr20 | 55020956 | + | 4128 | 1633 | 211 | 3534 | 1107 |
| ENST00000521652 | ASH2L | chr8 | 37991064 | + | ENST00000434344 | CASS4 | chr20 | 55020956 | + | 2816 | 1633 | 211 | 2223 | 670 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000343823 | ENST00000360314 | ASH2L | chr8 | 37991064 | + | CASS4 | chr20 | 55020956 | + | 0.001158774 | 0.9988412 |
| ENST00000343823 | ENST00000371336 | ASH2L | chr8 | 37991064 | + | CASS4 | chr20 | 55020956 | + | 0.000888876 | 0.9991111 |
| ENST00000343823 | ENST00000434344 | ASH2L | chr8 | 37991064 | + | CASS4 | chr20 | 55020956 | + | 0.005177649 | 0.9948224 |
| ENST00000250635 | ENST00000360314 | ASH2L | chr8 | 37991064 | + | CASS4 | chr20 | 55020956 | + | 0.000885526 | 0.99911445 |
| ENST00000250635 | ENST00000371336 | ASH2L | chr8 | 37991064 | + | CASS4 | chr20 | 55020956 | + | 0.000668422 | 0.9993316 |
| ENST00000250635 | ENST00000434344 | ASH2L | chr8 | 37991064 | + | CASS4 | chr20 | 55020956 | + | 0.005203725 | 0.99479634 |
| ENST00000545394 | ENST00000360314 | ASH2L | chr8 | 37991064 | + | CASS4 | chr20 | 55020956 | + | 0.001160101 | 0.9988399 |
| ENST00000545394 | ENST00000371336 | ASH2L | chr8 | 37991064 | + | CASS4 | chr20 | 55020956 | + | 0.000861284 | 0.9991387 |
| ENST00000545394 | ENST00000434344 | ASH2L | chr8 | 37991064 | + | CASS4 | chr20 | 55020956 | + | 0.003019933 | 0.99698 |
| ENST00000428278 | ENST00000360314 | ASH2L | chr8 | 37991064 | + | CASS4 | chr20 | 55020956 | + | 0.001229387 | 0.99877053 |
| ENST00000428278 | ENST00000371336 | ASH2L | chr8 | 37991064 | + | CASS4 | chr20 | 55020956 | + | 0.00096697 | 0.9990331 |
| ENST00000428278 | ENST00000434344 | ASH2L | chr8 | 37991064 | + | CASS4 | chr20 | 55020956 | + | 0.005401626 | 0.9945984 |
| ENST00000521652 | ENST00000360314 | ASH2L | chr8 | 37991064 | + | CASS4 | chr20 | 55020956 | + | 0.000935717 | 0.99906427 |
| ENST00000521652 | ENST00000371336 | ASH2L | chr8 | 37991064 | + | CASS4 | chr20 | 55020956 | + | 0.00074694 | 0.9992531 |
| ENST00000521652 | ENST00000434344 | ASH2L | chr8 | 37991064 | + | CASS4 | chr20 | 55020956 | + | 0.004800474 | 0.99519944 |
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Fusion Genomic Features for ASH2L-CASS4 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| ASH2L | chr8 | 37991064 | + | CASS4 | chr20 | 55020955 | + | 1.67E-07 | 0.9999999 |
| ASH2L | chr8 | 37991064 | + | CASS4 | chr20 | 55020955 | + | 1.67E-07 | 0.9999999 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for ASH2L-CASS4 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr8:37991064/chr20:55020956) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | . |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | ASH2L | chr8:37991064 | chr20:55020956 | ENST00000250635 | + | 13 | 15 | 67_177 | 446 | 502.0 | Region | Note=DNA-binding |
| Hgene | ASH2L | chr8:37991064 | chr20:55020956 | ENST00000343823 | + | 13 | 16 | 67_177 | 540 | 629.0 | Region | Note=DNA-binding |
| Hgene | ASH2L | chr8:37991064 | chr20:55020956 | ENST00000428278 | + | 13 | 16 | 67_177 | 446 | 535.0 | Region | Note=DNA-binding |
| Hgene | ASH2L | chr8:37991064 | chr20:55020956 | ENST00000521652 | + | 13 | 15 | 67_177 | 446 | 502.0 | Region | Note=DNA-binding |
| Hgene | ASH2L | chr8:37991064 | chr20:55020956 | ENST00000250635 | + | 13 | 15 | 117_150 | 446 | 502.0 | Zinc finger | Note=C4-type |
| Hgene | ASH2L | chr8:37991064 | chr20:55020956 | ENST00000250635 | + | 13 | 15 | 1_66 | 446 | 502.0 | Zinc finger | Note=PHD-type%3B atypical |
| Hgene | ASH2L | chr8:37991064 | chr20:55020956 | ENST00000343823 | + | 13 | 16 | 117_150 | 540 | 629.0 | Zinc finger | Note=C4-type |
| Hgene | ASH2L | chr8:37991064 | chr20:55020956 | ENST00000343823 | + | 13 | 16 | 1_66 | 540 | 629.0 | Zinc finger | Note=PHD-type%3B atypical |
| Hgene | ASH2L | chr8:37991064 | chr20:55020956 | ENST00000428278 | + | 13 | 16 | 117_150 | 446 | 535.0 | Zinc finger | Note=C4-type |
| Hgene | ASH2L | chr8:37991064 | chr20:55020956 | ENST00000428278 | + | 13 | 16 | 1_66 | 446 | 535.0 | Zinc finger | Note=PHD-type%3B atypical |
| Hgene | ASH2L | chr8:37991064 | chr20:55020956 | ENST00000521652 | + | 13 | 15 | 117_150 | 446 | 502.0 | Zinc finger | Note=C4-type |
| Hgene | ASH2L | chr8:37991064 | chr20:55020956 | ENST00000521652 | + | 13 | 15 | 1_66 | 446 | 502.0 | Zinc finger | Note=PHD-type%3B atypical |
| Tgene | CASS4 | chr8:37991064 | chr20:55020956 | ENST00000360314 | 2 | 7 | 274_277 | 153 | 787.0 | Compositional bias | Note=Poly-Ser | |
| Tgene | CASS4 | chr8:37991064 | chr20:55020956 | ENST00000360314 | 2 | 7 | 373_429 | 153 | 787.0 | Compositional bias | Note=Ser-rich | |
| Tgene | CASS4 | chr8:37991064 | chr20:55020956 | ENST00000371336 | 1 | 6 | 274_277 | 153 | 787.0 | Compositional bias | Note=Poly-Ser | |
| Tgene | CASS4 | chr8:37991064 | chr20:55020956 | ENST00000371336 | 1 | 6 | 373_429 | 153 | 787.0 | Compositional bias | Note=Ser-rich | |
| Tgene | CASS4 | chr8:37991064 | chr20:55020956 | ENST00000434344 | 1 | 5 | 274_277 | 153 | 350.0 | Compositional bias | Note=Poly-Ser | |
| Tgene | CASS4 | chr8:37991064 | chr20:55020956 | ENST00000434344 | 1 | 5 | 373_429 | 153 | 350.0 | Compositional bias | Note=Ser-rich |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | ASH2L | chr8:37991064 | chr20:55020956 | ENST00000250635 | + | 13 | 15 | 360_583 | 446 | 502.0 | Domain | B30.2/SPRY |
| Hgene | ASH2L | chr8:37991064 | chr20:55020956 | ENST00000343823 | + | 13 | 16 | 360_583 | 540 | 629.0 | Domain | B30.2/SPRY |
| Hgene | ASH2L | chr8:37991064 | chr20:55020956 | ENST00000428278 | + | 13 | 16 | 360_583 | 446 | 535.0 | Domain | B30.2/SPRY |
| Hgene | ASH2L | chr8:37991064 | chr20:55020956 | ENST00000521652 | + | 13 | 15 | 360_583 | 446 | 502.0 | Domain | B30.2/SPRY |
| Tgene | CASS4 | chr8:37991064 | chr20:55020956 | ENST00000360314 | 2 | 7 | 11_73 | 153 | 787.0 | Domain | SH3 | |
| Tgene | CASS4 | chr8:37991064 | chr20:55020956 | ENST00000371336 | 1 | 6 | 11_73 | 153 | 787.0 | Domain | SH3 | |
| Tgene | CASS4 | chr8:37991064 | chr20:55020956 | ENST00000434344 | 1 | 5 | 11_73 | 153 | 350.0 | Domain | SH3 |
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Fusion Gene Sequence for ASH2L-CASS4 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >7125_7125_1_ASH2L-CASS4_ASH2L_chr8_37991064_ENST00000250635_CASS4_chr20_55020956_ENST00000360314_length(transcript)=3613nt_BP=1678nt CACAGCAACGCGCGCGAGAGAAGAGAGTATTCTCGCGAGAAGTCCAGGGGTGGCCGTGATGGCGGCGGCAGGAGCAGGACCTGGCCAGGA AGCGGGTGCCGGGCCTGGCCCAGGAGCGGTCGCAAATGCAACAGGGGCAGAAGAGGGGGAGATGAAGCCGGTGGCAGCGGGAGCAGCCGC TCCTCCTGGAGAGGGGATCTCTGCTGCTCCGACAGTTGAGCCCAGTTCCGGGGAGGCTGAAGGCGGGGAGGCAAACTTGGTCGATGTAAG CGGTGGCTTGGAGACAGAATCATCTAATGGAAAAGATACACTAGAAGGTGCTGGGGATACATCAGAGGTGATGGATACTCAGGCGGGCTC CGTGGATGAAGAGAATGGCCGACAGTTGGGTGAGGTAGAGCTGCAATGTGGGATTTGTACAAAATGGTTCACGGCTGACACATTTGGCAT AGATACCTCATCCTGTCTACCTTTCATGACCAACTACAGTTTTCATTGCAACGTCTGCCATCACAGTGGGAATACCTATTTCCTCCGGAA GCAAGCAAACTTGAAGGAAATGTGCCTTAGTGCTTTGGCCAACCTGACATGGCAGTCCCGAACACAGGATGAACATCCGAAGACAATGTT CTCCAAAGATAAGGATATTATACCATTTATTGATAAATACTGGGAGTGCATGACAACCAGACAGAGACCTGGGAAAATGACTTGGCCAAA TAACATTGTTAAAACAATGAGTAAAGAAAGAGATGTATTCTTGGTAAAGGAACACCCAGATCCAGGCAGTAAAGATCCAGAAGAAGATTA CCCCAAATTTGGACTTTTGGATCAGGACCTTAGTAACATTGGTCCTGCTTATGACAACCAAAAACAGAGCAGTGCTGTGTCTACTAGTGG GAATTTAAATGGGGGAATTGCAGCAGGAAGCAGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCAC CAAGAAGGCCCGGAGTGACCCTTTGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGCTA TCGGTATATTCTAGCTGAGCCTGATCCGCACGCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGA CCTCTACAGAGCCTGCTTGTATGAACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACTGT GGTTGGAGAGAAGGGCTACTCTATGGTGAGGGCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCC ACCAGATACCGCTGCCAGACTGGGTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGGCG GAGCAAAAAGGGAACCAAGTTCCACCAGTCCATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAA TCTTCCTGAAGACACAGAGACAGCCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTTGA GGAAAAAGACTTTGTGGATAAAGCAGAGAAGAGCCTGAAGCAGACTCCCCATAGTGAGGCCATCCTCACGCTTCCCAGACCTGTCCGGGC CTCACTGCCGACTCTGCCTTCCCAGGTGTATGACGTGCCTACCCAGCACCGGGGCCCCGTGGTCCTGAAGGAGCCAGAGAAGCAGCAGTT ATATGACATACCAGCCAGCCCCAAGAAGGCAGGACTCCATCCCCCAGACAGCCAAGCAAGTGGGCAGGGTGTTCCCCTGATATCAGTGAC TACCTTAAGAAGAGGCGGTTACAGCACATTACCAAATCCTCAGAAATCGGAATGGATTTATGACACTCCAGTGTCTCCAGGAAAGGCCAG CGTCAGAAACACGCCTCTCACCAGCTTTGCGGAAGAATCAAGGCCCCACGCTCTCCCCAGTTCCAGCTCCACTTTCTACAATCCTCCAAG TGGCAGATCCAGGTCCCTCACTCCACAACTGAATAACAATGTGCCCATGCAGAAAAAACTCAGCCTTCCAGAAATTCCTTCTTATGGCTT TCTTGTACCCAGAGGCACATTTCCTTTGGATGAAGATGTCAGCTACAAGGTTCCTTCAAGCTTTCTGATTCCCCGAGTGGAACAGCAGAA CACCAAGCCCAATATTTATGACATCCCTAAAGCAACGTCGAGTGTTTCTCAGGCTGGGAAGGAGCTGGAGAAAGCCAAGGAGGTGTCAGA GAATTCCGCGGGCCATAATTCCTCATGGTTCTCCAGACGGACAACTTCCCCATCTCCTGAACCGGACAGATTATCAGGTTCCAGTTCTGA CAGCAGAGCTAGCATCGTTTCCTCGTGCTCCACCACATCCACCGACGACTCCTCCAGCTCTTCCTCGGAGGAGTCAGCAAAGGAGCTCTC CTTGGACCTGGATGTGGCCAAGGAGACAGTGATGGCTCTGCAGCACAAGGTGGTCAGCTCTGTCGCTGGCCTGATGCTCTTTGTCAGCAG GAAGTGGAGATTCCGAGACTATCTGGAGGCCAACATTGATGCAATCCACAGGTCCACTGATCACATAGAAGAATCTGTAAGAGAATTTCT GGATTTTGCCCGAGGAGTCCATGGGACTGCCTGTAACCTCACTGACAGTAACCTTCAGAACAGAATTCGGGACCAGATGCAGACCATCTC CAACTCCTACCGCATCCTGCTTGAAACAAAGGAAAGCTTGGATAATCGCAATTGGCCTCTGGAAGTTCTTGTGACTGACAGTGTCCAGAA CAGCCCAGATGACCTTGAGAGGTTTGTCATGGTGGCACGGATGCTTCCAGAAGACATCAAGAGGTTTGCCTCCATTGTCATTGCCAATGG AAGGCTCCTTTTTAAGCGGAACTGTGAAAAGGAAGAGACTGTGCAGTTGACCCCAAATGCAGAATTTAAGTGTGAAAAATACATCCAGCC TCCCCAAAGAGAAACTGAATCACACCAAAAGAGTACCCCTTCCACTAAGCAAAGGGAAGATGAACACTCTTCTGAACTATTAAAGAAAAA TAGGGCAAATATCTGTGGACAGAATCCTGGCCCTCTTATACCTCAGCCTTCGAGTCAACAGACTCCTGAGAGGAAACCCCGCTTATCTGA ACACTGCCGGCTCTACTTTGGGGCGCTCTTCAAAGCCATCAGCGCATTTCACGGCAGCCTCAGCAGCAGCCAGCCCGCGGAGATCATCAC TCAGAGCAAGCTGGTCATCATGGTGGGACAGAAGCTGGTGGACACGCTGTGCATGGAGACCCAGGAGAGGGACGTGCGCAACGAGATCCT CCGTGGCAGCAGTCACCTCTGCAGCCTGCTCAAGGACGTAGCGCTGGCCACTAAGAATGCCGTGCTCACGTACCCCAGCCCTGCCGCGCT GGGGCACCTCCAGGCGGAGGCTGAGAAGCTGGAGCAACACACGCGGCAGTTCAGAGGGACACTGGGATGAGGACTGTCTACCTCCCTTCC TCCTCTGCTCACC >7125_7125_1_ASH2L-CASS4_ASH2L_chr8_37991064_ENST00000250635_CASS4_chr20_55020956_ENST00000360314_length(amino acids)=1173AA_BP=538 MAAAGAGPGQEAGAGPGPGAVANATGAEEGEMKPVAAGAAAPPGEGISAAPTVEPSSGEAEGGEANLVDVSGGLETESSNGKDTLEGAGD TSEVMDTQAGSVDEENGRQLGEVELQCGICTKWFTADTFGIDTSSCLPFMTNYSFHCNVCHHSGNTYFLRKQANLKEMCLSALANLTWQS RTQDEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMSKERDVFLVKEHPDPGSKDPEEDYPKFGLLDQDLSNIGPAYDN QKQSSAVSTSGNLNGGIAAGSSGKGRGAKRKQQDGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLEL DCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEITVDEMPPDTAARLGWSQPLGNLQAP LGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEKSLKQTPHSE AILTLPRPVRASLPTLPSQVYDVPTQHRGPVVLKEPEKQQLYDIPASPKKAGLHPPDSQASGQGVPLISVTTLRRGGYSTLPNPQKSEWI YDTPVSPGKASVRNTPLTSFAEESRPHALPSSSSTFYNPPSGRSRSLTPQLNNNVPMQKKLSLPEIPSYGFLVPRGTFPLDEDVSYKVPS SFLIPRVEQQNTKPNIYDIPKATSSVSQAGKELEKAKEVSENSAGHNSSWFSRRTTSPSPEPDRLSGSSSDSRASIVSSCSTTSTDDSSS SSSEESAKELSLDLDVAKETVMALQHKVVSSVAGLMLFVSRKWRFRDYLEANIDAIHRSTDHIEESVREFLDFARGVHGTACNLTDSNLQ NRIRDQMQTISNSYRILLETKESLDNRNWPLEVLVTDSVQNSPDDLERFVMVARMLPEDIKRFASIVIANGRLLFKRNCEKEETVQLTPN AEFKCEKYIQPPQRETESHQKSTPSTKQREDEHSSELLKKNRANICGQNPGPLIPQPSSQQTPERKPRLSEHCRLYFGALFKAISAFHGS LSSSQPAEIITQSKLVIMVGQKLVDTLCMETQERDVRNEILRGSSHLCSLLKDVALATKNAVLTYPSPAALGHLQAEAEKLEQHTRQFRG TLG -------------------------------------------------------------- >7125_7125_2_ASH2L-CASS4_ASH2L_chr8_37991064_ENST00000250635_CASS4_chr20_55020956_ENST00000371336_length(transcript)=4173nt_BP=1678nt CACAGCAACGCGCGCGAGAGAAGAGAGTATTCTCGCGAGAAGTCCAGGGGTGGCCGTGATGGCGGCGGCAGGAGCAGGACCTGGCCAGGA AGCGGGTGCCGGGCCTGGCCCAGGAGCGGTCGCAAATGCAACAGGGGCAGAAGAGGGGGAGATGAAGCCGGTGGCAGCGGGAGCAGCCGC TCCTCCTGGAGAGGGGATCTCTGCTGCTCCGACAGTTGAGCCCAGTTCCGGGGAGGCTGAAGGCGGGGAGGCAAACTTGGTCGATGTAAG CGGTGGCTTGGAGACAGAATCATCTAATGGAAAAGATACACTAGAAGGTGCTGGGGATACATCAGAGGTGATGGATACTCAGGCGGGCTC CGTGGATGAAGAGAATGGCCGACAGTTGGGTGAGGTAGAGCTGCAATGTGGGATTTGTACAAAATGGTTCACGGCTGACACATTTGGCAT AGATACCTCATCCTGTCTACCTTTCATGACCAACTACAGTTTTCATTGCAACGTCTGCCATCACAGTGGGAATACCTATTTCCTCCGGAA GCAAGCAAACTTGAAGGAAATGTGCCTTAGTGCTTTGGCCAACCTGACATGGCAGTCCCGAACACAGGATGAACATCCGAAGACAATGTT CTCCAAAGATAAGGATATTATACCATTTATTGATAAATACTGGGAGTGCATGACAACCAGACAGAGACCTGGGAAAATGACTTGGCCAAA TAACATTGTTAAAACAATGAGTAAAGAAAGAGATGTATTCTTGGTAAAGGAACACCCAGATCCAGGCAGTAAAGATCCAGAAGAAGATTA CCCCAAATTTGGACTTTTGGATCAGGACCTTAGTAACATTGGTCCTGCTTATGACAACCAAAAACAGAGCAGTGCTGTGTCTACTAGTGG GAATTTAAATGGGGGAATTGCAGCAGGAAGCAGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCAC CAAGAAGGCCCGGAGTGACCCTTTGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGCTA TCGGTATATTCTAGCTGAGCCTGATCCGCACGCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGA CCTCTACAGAGCCTGCTTGTATGAACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACTGT GGTTGGAGAGAAGGGCTACTCTATGGTGAGGGCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCC ACCAGATACCGCTGCCAGACTGGGTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGGCG GAGCAAAAAGGGAACCAAGTTCCACCAGTCCATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAA TCTTCCTGAAGACACAGAGACAGCCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTTGA GGAAAAAGACTTTGTGGATAAAGCAGAGAAGAGCCTGAAGCAGACTCCCCATAGTGAGGCCATCCTCACGCTTCCCAGACCTGTCCGGGC CTCACTGCCGACTCTGCCTTCCCAGGTGTATGACGTGCCTACCCAGCACCGGGGCCCCGTGGTCCTGAAGGAGCCAGAGAAGCAGCAGTT ATATGACATACCAGCCAGCCCCAAGAAGGCAGGACTCCATCCCCCAGACAGCCAAGCAAGTGGGCAGGGTGTTCCCCTGATATCAGTGAC TACCTTAAGAAGAGGCGGTTACAGCACATTACCAAATCCTCAGAAATCGGAATGGATTTATGACACTCCAGTGTCTCCAGGAAAGGCCAG CGTCAGAAACACGCCTCTCACCAGCTTTGCGGAAGAATCAAGGCCCCACGCTCTCCCCAGTTCCAGCTCCACTTTCTACAATCCTCCAAG TGGCAGATCCAGGTCCCTCACTCCACAACTGAATAACAATGTGCCCATGCAGAAAAAACTCAGCCTTCCAGAAATTCCTTCTTATGGCTT TCTTGTACCCAGAGGCACATTTCCTTTGGATGAAGATGTCAGCTACAAGGTTCCTTCAAGCTTTCTGATTCCCCGAGTGGAACAGCAGAA CACCAAGCCCAATATTTATGACATCCCTAAAGCAACGTCGAGTGTTTCTCAGGCTGGGAAGGAGCTGGAGAAAGCCAAGGAGGTGTCAGA GAATTCCGCGGGCCATAATTCCTCATGGTTCTCCAGACGGACAACTTCCCCATCTCCTGAACCGGACAGATTATCAGGTTCCAGTTCTGA CAGCAGAGCTAGCATCGTTTCCTCGTGCTCCACCACATCCACCGACGACTCCTCCAGCTCTTCCTCGGAGGAGTCAGCAAAGGAGCTCTC CTTGGACCTGGATGTGGCCAAGGAGACAGTGATGGCTCTGCAGCACAAGGTGGTCAGCTCTGTCGCTGGCCTGATGCTCTTTGTCAGCAG GAAGTGGAGATTCCGAGACTATCTGGAGGCCAACATTGATGCAATCCACAGGTCCACTGATCACATAGAAGAATCTGTAAGAGAATTTCT GGATTTTGCCCGAGGAGTCCATGGGACTGCCTGTAACCTCACTGACAGTAACCTTCAGAACAGAATTCGGGACCAGATGCAGACCATCTC CAACTCCTACCGCATCCTGCTTGAAACAAAGGAAAGCTTGGATAATCGCAATTGGCCTCTGGAAGTTCTTGTGACTGACAGTGTCCAGAA CAGCCCAGATGACCTTGAGAGGTTTGTCATGGTGGCACGGATGCTTCCAGAAGACATCAAGAGGTTTGCCTCCATTGTCATTGCCAATGG AAGGCTCCTTTTTAAGCGGAACTGTGAAAAGGAAGAGACTGTGCAGTTGACCCCAAATGCAGAATTTAAGTGTGAAAAATACATCCAGCC TCCCCAAAGAGAAACTGAATCACACCAAAAGAGTACCCCTTCCACTAAGCAAAGGGAAGATGAACACTCTTCTGAACTATTAAAGAAAAA TAGGGCAAATATCTGTGGACAGAATCCTGGCCCTCTTATACCTCAGCCTTCGAGTCAACAGACTCCTGAGAGGAAACCCCGCTTATCTGA ACACTGCCGGCTCTACTTTGGGGCGCTCTTCAAAGCCATCAGCGCATTTCACGGCAGCCTCAGCAGCAGCCAGCCCGCGGAGATCATCAC TCAGAGCAAGCTGGTCATCATGGTGGGACAGAAGCTGGTGGACACGCTGTGCATGGAGACCCAGGAGAGGGACGTGCGCAACGAGATCCT CCGTGGCAGCAGTCACCTCTGCAGCCTGCTCAAGGACGTAGCGCTGGCCACTAAGAATGCCGTGCTCACGTACCCCAGCCCTGCCGCGCT GGGGCACCTCCAGGCGGAGGCTGAGAAGCTGGAGCAACACACGCGGCAGTTCAGAGGGACACTGGGATGAGGACTGTCTACCTCCCTTCC TCCTCTGCTCACCTCTCAGCTTCACACCCACAACTTGTGCAACTCTGCCCTATGGGAAAAGCCAGCCGGGGCATACACCAATGAGCTGAA ACAGACCTGGTGCCCAAAGCTGGTAGTACCAAGTGGCTAAGCAACCCCAGGGCATTGACTTACCCCGCAGGGGGTCAGGAAAGAGAGTCA GGTATGAGGTAAAGACCTTGTGAAGTTTAGCATATATGGAGTATGCAGTATCAGCTTGAAGTGACTTCGCAGAAATAATATTTTATATTG ATTAAATGTGTGCATGTTTTGTTTGTTTTTTGAGACAAAGTCTCACTCTGTCACACAGGCTGGAGTGCAGTGGCGCGATCTCAGCTCACT GCAACCTCCGCCTTCTGGGTTGAAGCAATTCTCCCGCCTCAGCCTCCAGAGTAGCTGGTACTACAGGTGTGCGCCACCATGCCCAGCTAA TTTTTGTATTTTTTTTTAATGAAAGGTCTCACATATTTATTACTGAACCCAGCCAACCAATGCATTCATAACAGATTCAGAAAGAAAAAA TATATTCCCAATAAAACATGTACAATTCTCCAG >7125_7125_2_ASH2L-CASS4_ASH2L_chr8_37991064_ENST00000250635_CASS4_chr20_55020956_ENST00000371336_length(amino acids)=1173AA_BP=538 MAAAGAGPGQEAGAGPGPGAVANATGAEEGEMKPVAAGAAAPPGEGISAAPTVEPSSGEAEGGEANLVDVSGGLETESSNGKDTLEGAGD TSEVMDTQAGSVDEENGRQLGEVELQCGICTKWFTADTFGIDTSSCLPFMTNYSFHCNVCHHSGNTYFLRKQANLKEMCLSALANLTWQS RTQDEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMSKERDVFLVKEHPDPGSKDPEEDYPKFGLLDQDLSNIGPAYDN QKQSSAVSTSGNLNGGIAAGSSGKGRGAKRKQQDGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLEL DCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEITVDEMPPDTAARLGWSQPLGNLQAP LGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEKSLKQTPHSE AILTLPRPVRASLPTLPSQVYDVPTQHRGPVVLKEPEKQQLYDIPASPKKAGLHPPDSQASGQGVPLISVTTLRRGGYSTLPNPQKSEWI YDTPVSPGKASVRNTPLTSFAEESRPHALPSSSSTFYNPPSGRSRSLTPQLNNNVPMQKKLSLPEIPSYGFLVPRGTFPLDEDVSYKVPS SFLIPRVEQQNTKPNIYDIPKATSSVSQAGKELEKAKEVSENSAGHNSSWFSRRTTSPSPEPDRLSGSSSDSRASIVSSCSTTSTDDSSS SSSEESAKELSLDLDVAKETVMALQHKVVSSVAGLMLFVSRKWRFRDYLEANIDAIHRSTDHIEESVREFLDFARGVHGTACNLTDSNLQ NRIRDQMQTISNSYRILLETKESLDNRNWPLEVLVTDSVQNSPDDLERFVMVARMLPEDIKRFASIVIANGRLLFKRNCEKEETVQLTPN AEFKCEKYIQPPQRETESHQKSTPSTKQREDEHSSELLKKNRANICGQNPGPLIPQPSSQQTPERKPRLSEHCRLYFGALFKAISAFHGS LSSSQPAEIITQSKLVIMVGQKLVDTLCMETQERDVRNEILRGSSHLCSLLKDVALATKNAVLTYPSPAALGHLQAEAEKLEQHTRQFRG TLG -------------------------------------------------------------- >7125_7125_3_ASH2L-CASS4_ASH2L_chr8_37991064_ENST00000250635_CASS4_chr20_55020956_ENST00000434344_length(transcript)=2861nt_BP=1678nt CACAGCAACGCGCGCGAGAGAAGAGAGTATTCTCGCGAGAAGTCCAGGGGTGGCCGTGATGGCGGCGGCAGGAGCAGGACCTGGCCAGGA AGCGGGTGCCGGGCCTGGCCCAGGAGCGGTCGCAAATGCAACAGGGGCAGAAGAGGGGGAGATGAAGCCGGTGGCAGCGGGAGCAGCCGC TCCTCCTGGAGAGGGGATCTCTGCTGCTCCGACAGTTGAGCCCAGTTCCGGGGAGGCTGAAGGCGGGGAGGCAAACTTGGTCGATGTAAG CGGTGGCTTGGAGACAGAATCATCTAATGGAAAAGATACACTAGAAGGTGCTGGGGATACATCAGAGGTGATGGATACTCAGGCGGGCTC CGTGGATGAAGAGAATGGCCGACAGTTGGGTGAGGTAGAGCTGCAATGTGGGATTTGTACAAAATGGTTCACGGCTGACACATTTGGCAT AGATACCTCATCCTGTCTACCTTTCATGACCAACTACAGTTTTCATTGCAACGTCTGCCATCACAGTGGGAATACCTATTTCCTCCGGAA GCAAGCAAACTTGAAGGAAATGTGCCTTAGTGCTTTGGCCAACCTGACATGGCAGTCCCGAACACAGGATGAACATCCGAAGACAATGTT CTCCAAAGATAAGGATATTATACCATTTATTGATAAATACTGGGAGTGCATGACAACCAGACAGAGACCTGGGAAAATGACTTGGCCAAA TAACATTGTTAAAACAATGAGTAAAGAAAGAGATGTATTCTTGGTAAAGGAACACCCAGATCCAGGCAGTAAAGATCCAGAAGAAGATTA CCCCAAATTTGGACTTTTGGATCAGGACCTTAGTAACATTGGTCCTGCTTATGACAACCAAAAACAGAGCAGTGCTGTGTCTACTAGTGG GAATTTAAATGGGGGAATTGCAGCAGGAAGCAGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCAC CAAGAAGGCCCGGAGTGACCCTTTGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGCTA TCGGTATATTCTAGCTGAGCCTGATCCGCACGCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGA CCTCTACAGAGCCTGCTTGTATGAACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACTGT GGTTGGAGAGAAGGGCTACTCTATGGTGAGGGCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCC ACCAGATACCGCTGCCAGACTGGGTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGGCG GAGCAAAAAGGGAACCAAGTTCCACCAGTCCATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAA TCTTCCTGAAGACACAGAGACAGCCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTTGA GGAAAAAGACTTTGTGGATAAAGCAGAGAAGAGCCTGAAGCAGACTCCCCATAGTGAGGCCATCCTCACGCTTCCCAGACCTGTCCGGGC CTCACTGCCGACTCTGCCTTCCCAGGTGTATGACGTGCCTACCCAGCACCGGGGCCCCGTGGTCCTGAAGGAGCCAGAGAAGCAGCAGTT ATATGACATACCAGCCAGCCCCAAGAAGGCAGGACTCCATCCCCCAGACAGCCAAGCAAGTAATCCTGGCCCTCTTATACCTCAGCCTTC GAGTCAACAGACTCCTGAGAGGAAACCCCGCTTATCTGAACACTGCCGGCTCTACTTTGGGGCGCTCTTCAAAGCCATCAGCGCATTTCA CGGCAGCCTCAGCAGCAGCCAGCCCGCGGAGATCATCACTCAGAGCAAGCTGGTCATCATGGTGGGACAGAAGCTGGTGGACACGCTGTG CATGGAGACCCAGGAGAGGGACGTGCGCAACGAGATCCTCCGTGGCAGCAGTCACCTCTGCAGCCTGCTCAAGGACGTAGCGCTGGCCAC TAAGAATGCCGTGCTCACGTACCCCAGCCCTGCCGCGCTGGGGCACCTCCAGGCGGAGGCTGAGAAGCTGGAGCAACACACGCGGCAGTT CAGAGGGACACTGGGATGAGGACTGTCTACCTCCCTTCCTCCTCTGCTCACCTCTCAGCTTCACACCCACAACTTGTGCAACTCTGCCCT ATGGGAAAAGCCAGCCGGGGCATACACCAATGAGCTGAAACAGACCTGGTGCCCAAAGCTGGTAGTACCAAGTGGCTAAGCAACCCCAGG GCATTGACTTACCCCGCAGGGGGTCAGGAAAGAGAGTCAGGTATGAGGTAAAGACCTTGTGAAGTTTAGCATATATGGAGTATGCAGTAT CAGCTTGAAGTGACTTCGCAGAAATAATATTTTATATTGATTAAATGTGTGCATGTTTTGTTTGTTTTTTGAGACAAAGTCTCACTCTGT CACACAGGCTGGAGTGCAGTGGCGCGATCTCAGCTCACTGCAACCTCCGCCTTCTGGGTTGAAGCAATTCTCCCGCCTCAGCCTCCAGAG TAGCTGGTACTACAGGTGTGCGCCACCATGCCCAGCTAATTTTTGTATTTTTTTTTAATGAAAGGTCTCACATATTTATTACTGAACCCA GCCAACCAATGCATTCATAACAGATTCAGAAAGAAAAAATATATTCCCAATAAAACATGTACAATTCTCCA >7125_7125_3_ASH2L-CASS4_ASH2L_chr8_37991064_ENST00000250635_CASS4_chr20_55020956_ENST00000434344_length(amino acids)=736AA_BP=538 MAAAGAGPGQEAGAGPGPGAVANATGAEEGEMKPVAAGAAAPPGEGISAAPTVEPSSGEAEGGEANLVDVSGGLETESSNGKDTLEGAGD TSEVMDTQAGSVDEENGRQLGEVELQCGICTKWFTADTFGIDTSSCLPFMTNYSFHCNVCHHSGNTYFLRKQANLKEMCLSALANLTWQS RTQDEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMSKERDVFLVKEHPDPGSKDPEEDYPKFGLLDQDLSNIGPAYDN QKQSSAVSTSGNLNGGIAAGSSGKGRGAKRKQQDGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLEL DCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEITVDEMPPDTAARLGWSQPLGNLQAP LGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEKSLKQTPHSE AILTLPRPVRASLPTLPSQVYDVPTQHRGPVVLKEPEKQQLYDIPASPKKAGLHPPDSQASNPGPLIPQPSSQQTPERKPRLSEHCRLYF GALFKAISAFHGSLSSSQPAEIITQSKLVIMVGQKLVDTLCMETQERDVRNEILRGSSHLCSLLKDVALATKNAVLTYPSPAALGHLQAE AEKLEQHTRQFRGTLG -------------------------------------------------------------- >7125_7125_4_ASH2L-CASS4_ASH2L_chr8_37991064_ENST00000343823_CASS4_chr20_55020956_ENST00000360314_length(transcript)=3864nt_BP=1929nt GCAGAATATCCAGTCGTAGCCACGAAAATACGCCGCGTCAGTCCCTGACTCGAAAGGAAGTCCTCCAGAGAGCCGCACTAACCATCTAGC TTCCTCCACCTTCAGCCTGCCAGGCCCGCGGCCACCGCCGGCGCGGGAGGCCGGCCCACCTCTGCCCGCGCGCCTGGCCTTAAAGCGGTC GTGGAATTATGCTTCCTCAGGCAGGCGGTGGACGCACCGCGGGCTTTTTCTGTTTGAAGACTACAGCGTCACACAGCAACGCGCGCGAGA GAAGAGAGTATTCTCGCGAGAAGTCCAGGGGTGGCCGTGATGGCGGCGGCAGGAGCAGGACCTGGCCAGGAAGCGGGTGCCGGGCCTGGC CCAGGAGCGGTCGCAAATGCAACAGGGGCAGAAGAGGGGGAGATGAAGCCGGTGGCAGCGGGAGCAGCCGCTCCTCCTGGAGAGGGGATC TCTGCTGCTCCGACAGTTGAGCCCAGTTCCGGGGAGGCTGAAGGCGGGGAGGCAAACTTGGTCGATGTAAGCGGTGGCTTGGAGACAGAA TCATCTAATGGAAAAGATACACTAGAAGGTGCTGGGGATACATCAGAGGTGATGGATACTCAGGCGGGCTCCGTGGATGAAGAGAATGGC CGACAGTTGGGTGAGGTAGAGCTGCAATGTGGGATTTGTACAAAATGGTTCACGGCTGACACATTTGGCATAGATACCTCATCCTGTCTA CCTTTCATGACCAACTACAGTTTTCATTGCAACGTCTGCCATCACAGTGGGAATACCTATTTCCTCCGGAAGCAAGCAAACTTGAAGGAA ATGTGCCTTAGTGCTTTGGCCAACCTGACATGGCAGTCCCGAACACAGGATGAACATCCGAAGACAATGTTCTCCAAAGATAAGGATATT ATACCATTTATTGATAAATACTGGGAGTGCATGACAACCAGACAGAGACCTGGGAAAATGACTTGGCCAAATAACATTGTTAAAACAATG AGTAAAGAAAGAGATGTATTCTTGGTAAAGGAACACCCAGATCCAGGCAGTAAAGATCCAGAAGAAGATTACCCCAAATTTGGACTTTTG GATCAGGACCTTAGTAACATTGGTCCTGCTTATGACAACCAAAAACAGAGCAGTGCTGTGTCTACTAGTGGGAATTTAAATGGGGGAATT GCAGCAGGAAGCAGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCACCAAGAAGGCCCGGAGTGAC CCTTTGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGCTATCGGTATATTCTAGCTGAG CCTGATCCGCACGCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGACCTCTACAGAGCCTGCTTG TATGAACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACTGTGGTTGGAGAGAAGGGCTAC TCTATGGTGAGGGCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCCACCAGATACCGCTGCCAGA CTGGGTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGGCGGAGCAAAAAGGGAACCAAG TTCCACCAGTCCATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAATCTTCCTGAAGACACAGAG ACAGCCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTTGAGGAAAAAGACTTTGTGGAT AAAGCAGAGAAGAGCCTGAAGCAGACTCCCCATAGTGAGGCCATCCTCACGCTTCCCAGACCTGTCCGGGCCTCACTGCCGACTCTGCCT TCCCAGGTGTATGACGTGCCTACCCAGCACCGGGGCCCCGTGGTCCTGAAGGAGCCAGAGAAGCAGCAGTTATATGACATACCAGCCAGC CCCAAGAAGGCAGGACTCCATCCCCCAGACAGCCAAGCAAGTGGGCAGGGTGTTCCCCTGATATCAGTGACTACCTTAAGAAGAGGCGGT TACAGCACATTACCAAATCCTCAGAAATCGGAATGGATTTATGACACTCCAGTGTCTCCAGGAAAGGCCAGCGTCAGAAACACGCCTCTC ACCAGCTTTGCGGAAGAATCAAGGCCCCACGCTCTCCCCAGTTCCAGCTCCACTTTCTACAATCCTCCAAGTGGCAGATCCAGGTCCCTC ACTCCACAACTGAATAACAATGTGCCCATGCAGAAAAAACTCAGCCTTCCAGAAATTCCTTCTTATGGCTTTCTTGTACCCAGAGGCACA TTTCCTTTGGATGAAGATGTCAGCTACAAGGTTCCTTCAAGCTTTCTGATTCCCCGAGTGGAACAGCAGAACACCAAGCCCAATATTTAT GACATCCCTAAAGCAACGTCGAGTGTTTCTCAGGCTGGGAAGGAGCTGGAGAAAGCCAAGGAGGTGTCAGAGAATTCCGCGGGCCATAAT TCCTCATGGTTCTCCAGACGGACAACTTCCCCATCTCCTGAACCGGACAGATTATCAGGTTCCAGTTCTGACAGCAGAGCTAGCATCGTT TCCTCGTGCTCCACCACATCCACCGACGACTCCTCCAGCTCTTCCTCGGAGGAGTCAGCAAAGGAGCTCTCCTTGGACCTGGATGTGGCC AAGGAGACAGTGATGGCTCTGCAGCACAAGGTGGTCAGCTCTGTCGCTGGCCTGATGCTCTTTGTCAGCAGGAAGTGGAGATTCCGAGAC TATCTGGAGGCCAACATTGATGCAATCCACAGGTCCACTGATCACATAGAAGAATCTGTAAGAGAATTTCTGGATTTTGCCCGAGGAGTC CATGGGACTGCCTGTAACCTCACTGACAGTAACCTTCAGAACAGAATTCGGGACCAGATGCAGACCATCTCCAACTCCTACCGCATCCTG CTTGAAACAAAGGAAAGCTTGGATAATCGCAATTGGCCTCTGGAAGTTCTTGTGACTGACAGTGTCCAGAACAGCCCAGATGACCTTGAG AGGTTTGTCATGGTGGCACGGATGCTTCCAGAAGACATCAAGAGGTTTGCCTCCATTGTCATTGCCAATGGAAGGCTCCTTTTTAAGCGG AACTGTGAAAAGGAAGAGACTGTGCAGTTGACCCCAAATGCAGAATTTAAGTGTGAAAAATACATCCAGCCTCCCCAAAGAGAAACTGAA TCACACCAAAAGAGTACCCCTTCCACTAAGCAAAGGGAAGATGAACACTCTTCTGAACTATTAAAGAAAAATAGGGCAAATATCTGTGGA CAGAATCCTGGCCCTCTTATACCTCAGCCTTCGAGTCAACAGACTCCTGAGAGGAAACCCCGCTTATCTGAACACTGCCGGCTCTACTTT GGGGCGCTCTTCAAAGCCATCAGCGCATTTCACGGCAGCCTCAGCAGCAGCCAGCCCGCGGAGATCATCACTCAGAGCAAGCTGGTCATC ATGGTGGGACAGAAGCTGGTGGACACGCTGTGCATGGAGACCCAGGAGAGGGACGTGCGCAACGAGATCCTCCGTGGCAGCAGTCACCTC TGCAGCCTGCTCAAGGACGTAGCGCTGGCCACTAAGAATGCCGTGCTCACGTACCCCAGCCCTGCCGCGCTGGGGCACCTCCAGGCGGAG GCTGAGAAGCTGGAGCAACACACGCGGCAGTTCAGAGGGACACTGGGATGAGGACTGTCTACCTCCCTTCCTCCTCTGCTCACC >7125_7125_4_ASH2L-CASS4_ASH2L_chr8_37991064_ENST00000343823_CASS4_chr20_55020956_ENST00000360314_length(amino acids)=1173AA_BP=538 MAAAGAGPGQEAGAGPGPGAVANATGAEEGEMKPVAAGAAAPPGEGISAAPTVEPSSGEAEGGEANLVDVSGGLETESSNGKDTLEGAGD TSEVMDTQAGSVDEENGRQLGEVELQCGICTKWFTADTFGIDTSSCLPFMTNYSFHCNVCHHSGNTYFLRKQANLKEMCLSALANLTWQS RTQDEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMSKERDVFLVKEHPDPGSKDPEEDYPKFGLLDQDLSNIGPAYDN QKQSSAVSTSGNLNGGIAAGSSGKGRGAKRKQQDGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLEL DCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEITVDEMPPDTAARLGWSQPLGNLQAP LGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEKSLKQTPHSE AILTLPRPVRASLPTLPSQVYDVPTQHRGPVVLKEPEKQQLYDIPASPKKAGLHPPDSQASGQGVPLISVTTLRRGGYSTLPNPQKSEWI YDTPVSPGKASVRNTPLTSFAEESRPHALPSSSSTFYNPPSGRSRSLTPQLNNNVPMQKKLSLPEIPSYGFLVPRGTFPLDEDVSYKVPS SFLIPRVEQQNTKPNIYDIPKATSSVSQAGKELEKAKEVSENSAGHNSSWFSRRTTSPSPEPDRLSGSSSDSRASIVSSCSTTSTDDSSS SSSEESAKELSLDLDVAKETVMALQHKVVSSVAGLMLFVSRKWRFRDYLEANIDAIHRSTDHIEESVREFLDFARGVHGTACNLTDSNLQ NRIRDQMQTISNSYRILLETKESLDNRNWPLEVLVTDSVQNSPDDLERFVMVARMLPEDIKRFASIVIANGRLLFKRNCEKEETVQLTPN AEFKCEKYIQPPQRETESHQKSTPSTKQREDEHSSELLKKNRANICGQNPGPLIPQPSSQQTPERKPRLSEHCRLYFGALFKAISAFHGS LSSSQPAEIITQSKLVIMVGQKLVDTLCMETQERDVRNEILRGSSHLCSLLKDVALATKNAVLTYPSPAALGHLQAEAEKLEQHTRQFRG TLG -------------------------------------------------------------- >7125_7125_5_ASH2L-CASS4_ASH2L_chr8_37991064_ENST00000343823_CASS4_chr20_55020956_ENST00000371336_length(transcript)=4424nt_BP=1929nt GCAGAATATCCAGTCGTAGCCACGAAAATACGCCGCGTCAGTCCCTGACTCGAAAGGAAGTCCTCCAGAGAGCCGCACTAACCATCTAGC TTCCTCCACCTTCAGCCTGCCAGGCCCGCGGCCACCGCCGGCGCGGGAGGCCGGCCCACCTCTGCCCGCGCGCCTGGCCTTAAAGCGGTC GTGGAATTATGCTTCCTCAGGCAGGCGGTGGACGCACCGCGGGCTTTTTCTGTTTGAAGACTACAGCGTCACACAGCAACGCGCGCGAGA GAAGAGAGTATTCTCGCGAGAAGTCCAGGGGTGGCCGTGATGGCGGCGGCAGGAGCAGGACCTGGCCAGGAAGCGGGTGCCGGGCCTGGC CCAGGAGCGGTCGCAAATGCAACAGGGGCAGAAGAGGGGGAGATGAAGCCGGTGGCAGCGGGAGCAGCCGCTCCTCCTGGAGAGGGGATC TCTGCTGCTCCGACAGTTGAGCCCAGTTCCGGGGAGGCTGAAGGCGGGGAGGCAAACTTGGTCGATGTAAGCGGTGGCTTGGAGACAGAA TCATCTAATGGAAAAGATACACTAGAAGGTGCTGGGGATACATCAGAGGTGATGGATACTCAGGCGGGCTCCGTGGATGAAGAGAATGGC CGACAGTTGGGTGAGGTAGAGCTGCAATGTGGGATTTGTACAAAATGGTTCACGGCTGACACATTTGGCATAGATACCTCATCCTGTCTA CCTTTCATGACCAACTACAGTTTTCATTGCAACGTCTGCCATCACAGTGGGAATACCTATTTCCTCCGGAAGCAAGCAAACTTGAAGGAA ATGTGCCTTAGTGCTTTGGCCAACCTGACATGGCAGTCCCGAACACAGGATGAACATCCGAAGACAATGTTCTCCAAAGATAAGGATATT ATACCATTTATTGATAAATACTGGGAGTGCATGACAACCAGACAGAGACCTGGGAAAATGACTTGGCCAAATAACATTGTTAAAACAATG AGTAAAGAAAGAGATGTATTCTTGGTAAAGGAACACCCAGATCCAGGCAGTAAAGATCCAGAAGAAGATTACCCCAAATTTGGACTTTTG GATCAGGACCTTAGTAACATTGGTCCTGCTTATGACAACCAAAAACAGAGCAGTGCTGTGTCTACTAGTGGGAATTTAAATGGGGGAATT GCAGCAGGAAGCAGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCACCAAGAAGGCCCGGAGTGAC CCTTTGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGCTATCGGTATATTCTAGCTGAG CCTGATCCGCACGCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGACCTCTACAGAGCCTGCTTG TATGAACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACTGTGGTTGGAGAGAAGGGCTAC TCTATGGTGAGGGCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCCACCAGATACCGCTGCCAGA CTGGGTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGGCGGAGCAAAAAGGGAACCAAG TTCCACCAGTCCATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAATCTTCCTGAAGACACAGAG ACAGCCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTTGAGGAAAAAGACTTTGTGGAT AAAGCAGAGAAGAGCCTGAAGCAGACTCCCCATAGTGAGGCCATCCTCACGCTTCCCAGACCTGTCCGGGCCTCACTGCCGACTCTGCCT TCCCAGGTGTATGACGTGCCTACCCAGCACCGGGGCCCCGTGGTCCTGAAGGAGCCAGAGAAGCAGCAGTTATATGACATACCAGCCAGC CCCAAGAAGGCAGGACTCCATCCCCCAGACAGCCAAGCAAGTGGGCAGGGTGTTCCCCTGATATCAGTGACTACCTTAAGAAGAGGCGGT TACAGCACATTACCAAATCCTCAGAAATCGGAATGGATTTATGACACTCCAGTGTCTCCAGGAAAGGCCAGCGTCAGAAACACGCCTCTC ACCAGCTTTGCGGAAGAATCAAGGCCCCACGCTCTCCCCAGTTCCAGCTCCACTTTCTACAATCCTCCAAGTGGCAGATCCAGGTCCCTC ACTCCACAACTGAATAACAATGTGCCCATGCAGAAAAAACTCAGCCTTCCAGAAATTCCTTCTTATGGCTTTCTTGTACCCAGAGGCACA TTTCCTTTGGATGAAGATGTCAGCTACAAGGTTCCTTCAAGCTTTCTGATTCCCCGAGTGGAACAGCAGAACACCAAGCCCAATATTTAT GACATCCCTAAAGCAACGTCGAGTGTTTCTCAGGCTGGGAAGGAGCTGGAGAAAGCCAAGGAGGTGTCAGAGAATTCCGCGGGCCATAAT TCCTCATGGTTCTCCAGACGGACAACTTCCCCATCTCCTGAACCGGACAGATTATCAGGTTCCAGTTCTGACAGCAGAGCTAGCATCGTT TCCTCGTGCTCCACCACATCCACCGACGACTCCTCCAGCTCTTCCTCGGAGGAGTCAGCAAAGGAGCTCTCCTTGGACCTGGATGTGGCC AAGGAGACAGTGATGGCTCTGCAGCACAAGGTGGTCAGCTCTGTCGCTGGCCTGATGCTCTTTGTCAGCAGGAAGTGGAGATTCCGAGAC TATCTGGAGGCCAACATTGATGCAATCCACAGGTCCACTGATCACATAGAAGAATCTGTAAGAGAATTTCTGGATTTTGCCCGAGGAGTC CATGGGACTGCCTGTAACCTCACTGACAGTAACCTTCAGAACAGAATTCGGGACCAGATGCAGACCATCTCCAACTCCTACCGCATCCTG CTTGAAACAAAGGAAAGCTTGGATAATCGCAATTGGCCTCTGGAAGTTCTTGTGACTGACAGTGTCCAGAACAGCCCAGATGACCTTGAG AGGTTTGTCATGGTGGCACGGATGCTTCCAGAAGACATCAAGAGGTTTGCCTCCATTGTCATTGCCAATGGAAGGCTCCTTTTTAAGCGG AACTGTGAAAAGGAAGAGACTGTGCAGTTGACCCCAAATGCAGAATTTAAGTGTGAAAAATACATCCAGCCTCCCCAAAGAGAAACTGAA TCACACCAAAAGAGTACCCCTTCCACTAAGCAAAGGGAAGATGAACACTCTTCTGAACTATTAAAGAAAAATAGGGCAAATATCTGTGGA CAGAATCCTGGCCCTCTTATACCTCAGCCTTCGAGTCAACAGACTCCTGAGAGGAAACCCCGCTTATCTGAACACTGCCGGCTCTACTTT GGGGCGCTCTTCAAAGCCATCAGCGCATTTCACGGCAGCCTCAGCAGCAGCCAGCCCGCGGAGATCATCACTCAGAGCAAGCTGGTCATC ATGGTGGGACAGAAGCTGGTGGACACGCTGTGCATGGAGACCCAGGAGAGGGACGTGCGCAACGAGATCCTCCGTGGCAGCAGTCACCTC TGCAGCCTGCTCAAGGACGTAGCGCTGGCCACTAAGAATGCCGTGCTCACGTACCCCAGCCCTGCCGCGCTGGGGCACCTCCAGGCGGAG GCTGAGAAGCTGGAGCAACACACGCGGCAGTTCAGAGGGACACTGGGATGAGGACTGTCTACCTCCCTTCCTCCTCTGCTCACCTCTCAG CTTCACACCCACAACTTGTGCAACTCTGCCCTATGGGAAAAGCCAGCCGGGGCATACACCAATGAGCTGAAACAGACCTGGTGCCCAAAG CTGGTAGTACCAAGTGGCTAAGCAACCCCAGGGCATTGACTTACCCCGCAGGGGGTCAGGAAAGAGAGTCAGGTATGAGGTAAAGACCTT GTGAAGTTTAGCATATATGGAGTATGCAGTATCAGCTTGAAGTGACTTCGCAGAAATAATATTTTATATTGATTAAATGTGTGCATGTTT TGTTTGTTTTTTGAGACAAAGTCTCACTCTGTCACACAGGCTGGAGTGCAGTGGCGCGATCTCAGCTCACTGCAACCTCCGCCTTCTGGG TTGAAGCAATTCTCCCGCCTCAGCCTCCAGAGTAGCTGGTACTACAGGTGTGCGCCACCATGCCCAGCTAATTTTTGTATTTTTTTTTAA TGAAAGGTCTCACATATTTATTACTGAACCCAGCCAACCAATGCATTCATAACAGATTCAGAAAGAAAAAATATATTCCCAATAAAACAT GTACAATTCTCCAG >7125_7125_5_ASH2L-CASS4_ASH2L_chr8_37991064_ENST00000343823_CASS4_chr20_55020956_ENST00000371336_length(amino acids)=1173AA_BP=538 MAAAGAGPGQEAGAGPGPGAVANATGAEEGEMKPVAAGAAAPPGEGISAAPTVEPSSGEAEGGEANLVDVSGGLETESSNGKDTLEGAGD TSEVMDTQAGSVDEENGRQLGEVELQCGICTKWFTADTFGIDTSSCLPFMTNYSFHCNVCHHSGNTYFLRKQANLKEMCLSALANLTWQS RTQDEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMSKERDVFLVKEHPDPGSKDPEEDYPKFGLLDQDLSNIGPAYDN QKQSSAVSTSGNLNGGIAAGSSGKGRGAKRKQQDGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLEL DCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEITVDEMPPDTAARLGWSQPLGNLQAP LGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEKSLKQTPHSE AILTLPRPVRASLPTLPSQVYDVPTQHRGPVVLKEPEKQQLYDIPASPKKAGLHPPDSQASGQGVPLISVTTLRRGGYSTLPNPQKSEWI YDTPVSPGKASVRNTPLTSFAEESRPHALPSSSSTFYNPPSGRSRSLTPQLNNNVPMQKKLSLPEIPSYGFLVPRGTFPLDEDVSYKVPS SFLIPRVEQQNTKPNIYDIPKATSSVSQAGKELEKAKEVSENSAGHNSSWFSRRTTSPSPEPDRLSGSSSDSRASIVSSCSTTSTDDSSS SSSEESAKELSLDLDVAKETVMALQHKVVSSVAGLMLFVSRKWRFRDYLEANIDAIHRSTDHIEESVREFLDFARGVHGTACNLTDSNLQ NRIRDQMQTISNSYRILLETKESLDNRNWPLEVLVTDSVQNSPDDLERFVMVARMLPEDIKRFASIVIANGRLLFKRNCEKEETVQLTPN AEFKCEKYIQPPQRETESHQKSTPSTKQREDEHSSELLKKNRANICGQNPGPLIPQPSSQQTPERKPRLSEHCRLYFGALFKAISAFHGS LSSSQPAEIITQSKLVIMVGQKLVDTLCMETQERDVRNEILRGSSHLCSLLKDVALATKNAVLTYPSPAALGHLQAEAEKLEQHTRQFRG TLG -------------------------------------------------------------- >7125_7125_6_ASH2L-CASS4_ASH2L_chr8_37991064_ENST00000343823_CASS4_chr20_55020956_ENST00000434344_length(transcript)=3112nt_BP=1929nt GCAGAATATCCAGTCGTAGCCACGAAAATACGCCGCGTCAGTCCCTGACTCGAAAGGAAGTCCTCCAGAGAGCCGCACTAACCATCTAGC TTCCTCCACCTTCAGCCTGCCAGGCCCGCGGCCACCGCCGGCGCGGGAGGCCGGCCCACCTCTGCCCGCGCGCCTGGCCTTAAAGCGGTC GTGGAATTATGCTTCCTCAGGCAGGCGGTGGACGCACCGCGGGCTTTTTCTGTTTGAAGACTACAGCGTCACACAGCAACGCGCGCGAGA GAAGAGAGTATTCTCGCGAGAAGTCCAGGGGTGGCCGTGATGGCGGCGGCAGGAGCAGGACCTGGCCAGGAAGCGGGTGCCGGGCCTGGC CCAGGAGCGGTCGCAAATGCAACAGGGGCAGAAGAGGGGGAGATGAAGCCGGTGGCAGCGGGAGCAGCCGCTCCTCCTGGAGAGGGGATC TCTGCTGCTCCGACAGTTGAGCCCAGTTCCGGGGAGGCTGAAGGCGGGGAGGCAAACTTGGTCGATGTAAGCGGTGGCTTGGAGACAGAA TCATCTAATGGAAAAGATACACTAGAAGGTGCTGGGGATACATCAGAGGTGATGGATACTCAGGCGGGCTCCGTGGATGAAGAGAATGGC CGACAGTTGGGTGAGGTAGAGCTGCAATGTGGGATTTGTACAAAATGGTTCACGGCTGACACATTTGGCATAGATACCTCATCCTGTCTA CCTTTCATGACCAACTACAGTTTTCATTGCAACGTCTGCCATCACAGTGGGAATACCTATTTCCTCCGGAAGCAAGCAAACTTGAAGGAA ATGTGCCTTAGTGCTTTGGCCAACCTGACATGGCAGTCCCGAACACAGGATGAACATCCGAAGACAATGTTCTCCAAAGATAAGGATATT ATACCATTTATTGATAAATACTGGGAGTGCATGACAACCAGACAGAGACCTGGGAAAATGACTTGGCCAAATAACATTGTTAAAACAATG AGTAAAGAAAGAGATGTATTCTTGGTAAAGGAACACCCAGATCCAGGCAGTAAAGATCCAGAAGAAGATTACCCCAAATTTGGACTTTTG GATCAGGACCTTAGTAACATTGGTCCTGCTTATGACAACCAAAAACAGAGCAGTGCTGTGTCTACTAGTGGGAATTTAAATGGGGGAATT GCAGCAGGAAGCAGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCACCAAGAAGGCCCGGAGTGAC CCTTTGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGCTATCGGTATATTCTAGCTGAG CCTGATCCGCACGCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGACCTCTACAGAGCCTGCTTG TATGAACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACTGTGGTTGGAGAGAAGGGCTAC TCTATGGTGAGGGCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCCACCAGATACCGCTGCCAGA CTGGGTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGGCGGAGCAAAAAGGGAACCAAG TTCCACCAGTCCATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAATCTTCCTGAAGACACAGAG ACAGCCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTTGAGGAAAAAGACTTTGTGGAT AAAGCAGAGAAGAGCCTGAAGCAGACTCCCCATAGTGAGGCCATCCTCACGCTTCCCAGACCTGTCCGGGCCTCACTGCCGACTCTGCCT TCCCAGGTGTATGACGTGCCTACCCAGCACCGGGGCCCCGTGGTCCTGAAGGAGCCAGAGAAGCAGCAGTTATATGACATACCAGCCAGC CCCAAGAAGGCAGGACTCCATCCCCCAGACAGCCAAGCAAGTAATCCTGGCCCTCTTATACCTCAGCCTTCGAGTCAACAGACTCCTGAG AGGAAACCCCGCTTATCTGAACACTGCCGGCTCTACTTTGGGGCGCTCTTCAAAGCCATCAGCGCATTTCACGGCAGCCTCAGCAGCAGC CAGCCCGCGGAGATCATCACTCAGAGCAAGCTGGTCATCATGGTGGGACAGAAGCTGGTGGACACGCTGTGCATGGAGACCCAGGAGAGG GACGTGCGCAACGAGATCCTCCGTGGCAGCAGTCACCTCTGCAGCCTGCTCAAGGACGTAGCGCTGGCCACTAAGAATGCCGTGCTCACG TACCCCAGCCCTGCCGCGCTGGGGCACCTCCAGGCGGAGGCTGAGAAGCTGGAGCAACACACGCGGCAGTTCAGAGGGACACTGGGATGA GGACTGTCTACCTCCCTTCCTCCTCTGCTCACCTCTCAGCTTCACACCCACAACTTGTGCAACTCTGCCCTATGGGAAAAGCCAGCCGGG GCATACACCAATGAGCTGAAACAGACCTGGTGCCCAAAGCTGGTAGTACCAAGTGGCTAAGCAACCCCAGGGCATTGACTTACCCCGCAG GGGGTCAGGAAAGAGAGTCAGGTATGAGGTAAAGACCTTGTGAAGTTTAGCATATATGGAGTATGCAGTATCAGCTTGAAGTGACTTCGC AGAAATAATATTTTATATTGATTAAATGTGTGCATGTTTTGTTTGTTTTTTGAGACAAAGTCTCACTCTGTCACACAGGCTGGAGTGCAG TGGCGCGATCTCAGCTCACTGCAACCTCCGCCTTCTGGGTTGAAGCAATTCTCCCGCCTCAGCCTCCAGAGTAGCTGGTACTACAGGTGT GCGCCACCATGCCCAGCTAATTTTTGTATTTTTTTTTAATGAAAGGTCTCACATATTTATTACTGAACCCAGCCAACCAATGCATTCATA ACAGATTCAGAAAGAAAAAATATATTCCCAATAAAACATGTACAATTCTCCA >7125_7125_6_ASH2L-CASS4_ASH2L_chr8_37991064_ENST00000343823_CASS4_chr20_55020956_ENST00000434344_length(amino acids)=736AA_BP=538 MAAAGAGPGQEAGAGPGPGAVANATGAEEGEMKPVAAGAAAPPGEGISAAPTVEPSSGEAEGGEANLVDVSGGLETESSNGKDTLEGAGD TSEVMDTQAGSVDEENGRQLGEVELQCGICTKWFTADTFGIDTSSCLPFMTNYSFHCNVCHHSGNTYFLRKQANLKEMCLSALANLTWQS RTQDEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMSKERDVFLVKEHPDPGSKDPEEDYPKFGLLDQDLSNIGPAYDN QKQSSAVSTSGNLNGGIAAGSSGKGRGAKRKQQDGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLEL DCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEITVDEMPPDTAARLGWSQPLGNLQAP LGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKSYLYFEEKDFVDKAEKSLKQTPHSE AILTLPRPVRASLPTLPSQVYDVPTQHRGPVVLKEPEKQQLYDIPASPKKAGLHPPDSQASNPGPLIPQPSSQQTPERKPRLSEHCRLYF GALFKAISAFHGSLSSSQPAEIITQSKLVIMVGQKLVDTLCMETQERDVRNEILRGSSHLCSLLKDVALATKNAVLTYPSPAALGHLQAE AEKLEQHTRQFRGTLG -------------------------------------------------------------- >7125_7125_7_ASH2L-CASS4_ASH2L_chr8_37991064_ENST00000428278_CASS4_chr20_55020956_ENST00000360314_length(transcript)=3714nt_BP=1779nt ATCCCGCGGCTCCTGGAGCCCTGCCGCCCGCCCCCTGCGAACCCAGGCCCCGCCGCCAATGGCTCGCCCTGCCTCTGCGCCGCTTGGCCC GTCCCCTCTCAAGCATATCTCGGATAACGCCCCTTCCGCACCTTTCACGGGCGGTGGGAGCTGAGGCTCCTGTCGTTATCTCTGATCCTT GCACCCTGGCAGGAAGCTGGTAGCTCACACTTTAACGGGAGGCCTTCACATATTCCAGAAAAGAAACCACTTTGCAGTGCCAGACTGGAA GAAGTAACGGTCACTCTGAAAACAGGGTGGGAGAGCTGCCTCTCTTTGAACCTCTCCCAGGACCAACTCTAACCCAGGGAGGCAAACTTG GTCGATGTAAGCGGTGGCTTGGAGACAGAATCATCTAATGGAAAAGATACACTAGAAGGTGCTGGGGATACATCAGAGGTGATGGATACT CAGGCGGGCTCCGTGGATGAAGAGAATGGCCGACAGTTGGGTGAGGTAGAGCTGCAATGTGGGATTTGTACAAAATGGTTCACGGCTGAC ACATTTGGCATAGATACCTCATCCTGTCTACCTTTCATGACCAACTACAGTTTTCATTGCAACGTCTGCCATCACAGTGGGAATACCTAT TTCCTCCGGAAGCAAGCAAACTTGAAGGAAATGTGCCTTAGTGCTTTGGCCAACCTGACATGGCAGTCCCGAACACAGGATGAACATCCG AAGACAATGTTCTCCAAAGATAAGGATATTATACCATTTATTGATAAATACTGGGAGTGCATGACAACCAGACAGAGACCTGGGAAAATG ACTTGGCCAAATAACATTGTTAAAACAATGAGTAAAGAAAGAGATGTATTCTTGGTAAAGGAACACCCAGATCCAGGCAGTAAAGATCCA GAAGAAGATTACCCCAAATTTGGACTTTTGGATCAGGACCTTAGTAACATTGGTCCTGCTTATGACAACCAAAAACAGAGCAGTGCTGTG TCTACTAGTGGGAATTTAAATGGGGGAATTGCAGCAGGAAGCAGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACC ACAGGGACCACCAAGAAGGCCCGGAGTGACCCTTTGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAAC AAAGATGGCTATCGGTATATTCTAGCTGAGCCTGATCCGCACGCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCT ATTCCTGGAGACCTCTACAGAGCCTGCTTGTATGAACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGAC CGGCTGACTGTGGTTGGAGAGAAGGGCTACTCTATGGTGAGGGCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTG GATGAGATGCCACCAGATACCGCTGCCAGACTGGGTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGC TATTCTTGGCGGAGCAAAAAGGGAACCAAGTTCCACCAGTCCATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGA TTTTATATTAATCTTCCTGAAGACACAGAGACAGCCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTAT TTGTATTTTGAGGAAAAAGACTTTGTGGATAAAGCAGAGAAGAGCCTGAAGCAGACTCCCCATAGTGAGGCCATCCTCACGCTTCCCAGA CCTGTCCGGGCCTCACTGCCGACTCTGCCTTCCCAGGTGTATGACGTGCCTACCCAGCACCGGGGCCCCGTGGTCCTGAAGGAGCCAGAG AAGCAGCAGTTATATGACATACCAGCCAGCCCCAAGAAGGCAGGACTCCATCCCCCAGACAGCCAAGCAAGTGGGCAGGGTGTTCCCCTG ATATCAGTGACTACCTTAAGAAGAGGCGGTTACAGCACATTACCAAATCCTCAGAAATCGGAATGGATTTATGACACTCCAGTGTCTCCA GGAAAGGCCAGCGTCAGAAACACGCCTCTCACCAGCTTTGCGGAAGAATCAAGGCCCCACGCTCTCCCCAGTTCCAGCTCCACTTTCTAC AATCCTCCAAGTGGCAGATCCAGGTCCCTCACTCCACAACTGAATAACAATGTGCCCATGCAGAAAAAACTCAGCCTTCCAGAAATTCCT TCTTATGGCTTTCTTGTACCCAGAGGCACATTTCCTTTGGATGAAGATGTCAGCTACAAGGTTCCTTCAAGCTTTCTGATTCCCCGAGTG GAACAGCAGAACACCAAGCCCAATATTTATGACATCCCTAAAGCAACGTCGAGTGTTTCTCAGGCTGGGAAGGAGCTGGAGAAAGCCAAG GAGGTGTCAGAGAATTCCGCGGGCCATAATTCCTCATGGTTCTCCAGACGGACAACTTCCCCATCTCCTGAACCGGACAGATTATCAGGT TCCAGTTCTGACAGCAGAGCTAGCATCGTTTCCTCGTGCTCCACCACATCCACCGACGACTCCTCCAGCTCTTCCTCGGAGGAGTCAGCA AAGGAGCTCTCCTTGGACCTGGATGTGGCCAAGGAGACAGTGATGGCTCTGCAGCACAAGGTGGTCAGCTCTGTCGCTGGCCTGATGCTC TTTGTCAGCAGGAAGTGGAGATTCCGAGACTATCTGGAGGCCAACATTGATGCAATCCACAGGTCCACTGATCACATAGAAGAATCTGTA AGAGAATTTCTGGATTTTGCCCGAGGAGTCCATGGGACTGCCTGTAACCTCACTGACAGTAACCTTCAGAACAGAATTCGGGACCAGATG CAGACCATCTCCAACTCCTACCGCATCCTGCTTGAAACAAAGGAAAGCTTGGATAATCGCAATTGGCCTCTGGAAGTTCTTGTGACTGAC AGTGTCCAGAACAGCCCAGATGACCTTGAGAGGTTTGTCATGGTGGCACGGATGCTTCCAGAAGACATCAAGAGGTTTGCCTCCATTGTC ATTGCCAATGGAAGGCTCCTTTTTAAGCGGAACTGTGAAAAGGAAGAGACTGTGCAGTTGACCCCAAATGCAGAATTTAAGTGTGAAAAA TACATCCAGCCTCCCCAAAGAGAAACTGAATCACACCAAAAGAGTACCCCTTCCACTAAGCAAAGGGAAGATGAACACTCTTCTGAACTA TTAAAGAAAAATAGGGCAAATATCTGTGGACAGAATCCTGGCCCTCTTATACCTCAGCCTTCGAGTCAACAGACTCCTGAGAGGAAACCC CGCTTATCTGAACACTGCCGGCTCTACTTTGGGGCGCTCTTCAAAGCCATCAGCGCATTTCACGGCAGCCTCAGCAGCAGCCAGCCCGCG GAGATCATCACTCAGAGCAAGCTGGTCATCATGGTGGGACAGAAGCTGGTGGACACGCTGTGCATGGAGACCCAGGAGAGGGACGTGCGC AACGAGATCCTCCGTGGCAGCAGTCACCTCTGCAGCCTGCTCAAGGACGTAGCGCTGGCCACTAAGAATGCCGTGCTCACGTACCCCAGC CCTGCCGCGCTGGGGCACCTCCAGGCGGAGGCTGAGAAGCTGGAGCAACACACGCGGCAGTTCAGAGGGACACTGGGATGAGGACTGTCT ACCTCCCTTCCTCCTCTGCTCACC >7125_7125_7_ASH2L-CASS4_ASH2L_chr8_37991064_ENST00000428278_CASS4_chr20_55020956_ENST00000360314_length(amino acids)=1107AA_BP=472 MVDVSGGLETESSNGKDTLEGAGDTSEVMDTQAGSVDEENGRQLGEVELQCGICTKWFTADTFGIDTSSCLPFMTNYSFHCNVCHHSGNT YFLRKQANLKEMCLSALANLTWQSRTQDEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMSKERDVFLVKEHPDPGSKD PEEDYPKFGLLDQDLSNIGPAYDNQKQSSAVSTSGNLNGGIAAGSSGKGRGAKRKQQDGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPF NKDGYRYILAEPDPHAPDPEKLELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEIT VDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKS YLYFEEKDFVDKAEKSLKQTPHSEAILTLPRPVRASLPTLPSQVYDVPTQHRGPVVLKEPEKQQLYDIPASPKKAGLHPPDSQASGQGVP LISVTTLRRGGYSTLPNPQKSEWIYDTPVSPGKASVRNTPLTSFAEESRPHALPSSSSTFYNPPSGRSRSLTPQLNNNVPMQKKLSLPEI PSYGFLVPRGTFPLDEDVSYKVPSSFLIPRVEQQNTKPNIYDIPKATSSVSQAGKELEKAKEVSENSAGHNSSWFSRRTTSPSPEPDRLS GSSSDSRASIVSSCSTTSTDDSSSSSSEESAKELSLDLDVAKETVMALQHKVVSSVAGLMLFVSRKWRFRDYLEANIDAIHRSTDHIEES VREFLDFARGVHGTACNLTDSNLQNRIRDQMQTISNSYRILLETKESLDNRNWPLEVLVTDSVQNSPDDLERFVMVARMLPEDIKRFASI VIANGRLLFKRNCEKEETVQLTPNAEFKCEKYIQPPQRETESHQKSTPSTKQREDEHSSELLKKNRANICGQNPGPLIPQPSSQQTPERK PRLSEHCRLYFGALFKAISAFHGSLSSSQPAEIITQSKLVIMVGQKLVDTLCMETQERDVRNEILRGSSHLCSLLKDVALATKNAVLTYP SPAALGHLQAEAEKLEQHTRQFRGTLG -------------------------------------------------------------- >7125_7125_8_ASH2L-CASS4_ASH2L_chr8_37991064_ENST00000428278_CASS4_chr20_55020956_ENST00000371336_length(transcript)=4274nt_BP=1779nt ATCCCGCGGCTCCTGGAGCCCTGCCGCCCGCCCCCTGCGAACCCAGGCCCCGCCGCCAATGGCTCGCCCTGCCTCTGCGCCGCTTGGCCC GTCCCCTCTCAAGCATATCTCGGATAACGCCCCTTCCGCACCTTTCACGGGCGGTGGGAGCTGAGGCTCCTGTCGTTATCTCTGATCCTT GCACCCTGGCAGGAAGCTGGTAGCTCACACTTTAACGGGAGGCCTTCACATATTCCAGAAAAGAAACCACTTTGCAGTGCCAGACTGGAA GAAGTAACGGTCACTCTGAAAACAGGGTGGGAGAGCTGCCTCTCTTTGAACCTCTCCCAGGACCAACTCTAACCCAGGGAGGCAAACTTG GTCGATGTAAGCGGTGGCTTGGAGACAGAATCATCTAATGGAAAAGATACACTAGAAGGTGCTGGGGATACATCAGAGGTGATGGATACT CAGGCGGGCTCCGTGGATGAAGAGAATGGCCGACAGTTGGGTGAGGTAGAGCTGCAATGTGGGATTTGTACAAAATGGTTCACGGCTGAC ACATTTGGCATAGATACCTCATCCTGTCTACCTTTCATGACCAACTACAGTTTTCATTGCAACGTCTGCCATCACAGTGGGAATACCTAT TTCCTCCGGAAGCAAGCAAACTTGAAGGAAATGTGCCTTAGTGCTTTGGCCAACCTGACATGGCAGTCCCGAACACAGGATGAACATCCG AAGACAATGTTCTCCAAAGATAAGGATATTATACCATTTATTGATAAATACTGGGAGTGCATGACAACCAGACAGAGACCTGGGAAAATG ACTTGGCCAAATAACATTGTTAAAACAATGAGTAAAGAAAGAGATGTATTCTTGGTAAAGGAACACCCAGATCCAGGCAGTAAAGATCCA GAAGAAGATTACCCCAAATTTGGACTTTTGGATCAGGACCTTAGTAACATTGGTCCTGCTTATGACAACCAAAAACAGAGCAGTGCTGTG TCTACTAGTGGGAATTTAAATGGGGGAATTGCAGCAGGAAGCAGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACC ACAGGGACCACCAAGAAGGCCCGGAGTGACCCTTTGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAAC AAAGATGGCTATCGGTATATTCTAGCTGAGCCTGATCCGCACGCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCT ATTCCTGGAGACCTCTACAGAGCCTGCTTGTATGAACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGAC CGGCTGACTGTGGTTGGAGAGAAGGGCTACTCTATGGTGAGGGCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTG GATGAGATGCCACCAGATACCGCTGCCAGACTGGGTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGC TATTCTTGGCGGAGCAAAAAGGGAACCAAGTTCCACCAGTCCATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGA TTTTATATTAATCTTCCTGAAGACACAGAGACAGCCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTAT TTGTATTTTGAGGAAAAAGACTTTGTGGATAAAGCAGAGAAGAGCCTGAAGCAGACTCCCCATAGTGAGGCCATCCTCACGCTTCCCAGA CCTGTCCGGGCCTCACTGCCGACTCTGCCTTCCCAGGTGTATGACGTGCCTACCCAGCACCGGGGCCCCGTGGTCCTGAAGGAGCCAGAG AAGCAGCAGTTATATGACATACCAGCCAGCCCCAAGAAGGCAGGACTCCATCCCCCAGACAGCCAAGCAAGTGGGCAGGGTGTTCCCCTG ATATCAGTGACTACCTTAAGAAGAGGCGGTTACAGCACATTACCAAATCCTCAGAAATCGGAATGGATTTATGACACTCCAGTGTCTCCA GGAAAGGCCAGCGTCAGAAACACGCCTCTCACCAGCTTTGCGGAAGAATCAAGGCCCCACGCTCTCCCCAGTTCCAGCTCCACTTTCTAC AATCCTCCAAGTGGCAGATCCAGGTCCCTCACTCCACAACTGAATAACAATGTGCCCATGCAGAAAAAACTCAGCCTTCCAGAAATTCCT TCTTATGGCTTTCTTGTACCCAGAGGCACATTTCCTTTGGATGAAGATGTCAGCTACAAGGTTCCTTCAAGCTTTCTGATTCCCCGAGTG GAACAGCAGAACACCAAGCCCAATATTTATGACATCCCTAAAGCAACGTCGAGTGTTTCTCAGGCTGGGAAGGAGCTGGAGAAAGCCAAG GAGGTGTCAGAGAATTCCGCGGGCCATAATTCCTCATGGTTCTCCAGACGGACAACTTCCCCATCTCCTGAACCGGACAGATTATCAGGT TCCAGTTCTGACAGCAGAGCTAGCATCGTTTCCTCGTGCTCCACCACATCCACCGACGACTCCTCCAGCTCTTCCTCGGAGGAGTCAGCA AAGGAGCTCTCCTTGGACCTGGATGTGGCCAAGGAGACAGTGATGGCTCTGCAGCACAAGGTGGTCAGCTCTGTCGCTGGCCTGATGCTC TTTGTCAGCAGGAAGTGGAGATTCCGAGACTATCTGGAGGCCAACATTGATGCAATCCACAGGTCCACTGATCACATAGAAGAATCTGTA AGAGAATTTCTGGATTTTGCCCGAGGAGTCCATGGGACTGCCTGTAACCTCACTGACAGTAACCTTCAGAACAGAATTCGGGACCAGATG CAGACCATCTCCAACTCCTACCGCATCCTGCTTGAAACAAAGGAAAGCTTGGATAATCGCAATTGGCCTCTGGAAGTTCTTGTGACTGAC AGTGTCCAGAACAGCCCAGATGACCTTGAGAGGTTTGTCATGGTGGCACGGATGCTTCCAGAAGACATCAAGAGGTTTGCCTCCATTGTC ATTGCCAATGGAAGGCTCCTTTTTAAGCGGAACTGTGAAAAGGAAGAGACTGTGCAGTTGACCCCAAATGCAGAATTTAAGTGTGAAAAA TACATCCAGCCTCCCCAAAGAGAAACTGAATCACACCAAAAGAGTACCCCTTCCACTAAGCAAAGGGAAGATGAACACTCTTCTGAACTA TTAAAGAAAAATAGGGCAAATATCTGTGGACAGAATCCTGGCCCTCTTATACCTCAGCCTTCGAGTCAACAGACTCCTGAGAGGAAACCC CGCTTATCTGAACACTGCCGGCTCTACTTTGGGGCGCTCTTCAAAGCCATCAGCGCATTTCACGGCAGCCTCAGCAGCAGCCAGCCCGCG GAGATCATCACTCAGAGCAAGCTGGTCATCATGGTGGGACAGAAGCTGGTGGACACGCTGTGCATGGAGACCCAGGAGAGGGACGTGCGC AACGAGATCCTCCGTGGCAGCAGTCACCTCTGCAGCCTGCTCAAGGACGTAGCGCTGGCCACTAAGAATGCCGTGCTCACGTACCCCAGC CCTGCCGCGCTGGGGCACCTCCAGGCGGAGGCTGAGAAGCTGGAGCAACACACGCGGCAGTTCAGAGGGACACTGGGATGAGGACTGTCT ACCTCCCTTCCTCCTCTGCTCACCTCTCAGCTTCACACCCACAACTTGTGCAACTCTGCCCTATGGGAAAAGCCAGCCGGGGCATACACC AATGAGCTGAAACAGACCTGGTGCCCAAAGCTGGTAGTACCAAGTGGCTAAGCAACCCCAGGGCATTGACTTACCCCGCAGGGGGTCAGG AAAGAGAGTCAGGTATGAGGTAAAGACCTTGTGAAGTTTAGCATATATGGAGTATGCAGTATCAGCTTGAAGTGACTTCGCAGAAATAAT ATTTTATATTGATTAAATGTGTGCATGTTTTGTTTGTTTTTTGAGACAAAGTCTCACTCTGTCACACAGGCTGGAGTGCAGTGGCGCGAT CTCAGCTCACTGCAACCTCCGCCTTCTGGGTTGAAGCAATTCTCCCGCCTCAGCCTCCAGAGTAGCTGGTACTACAGGTGTGCGCCACCA TGCCCAGCTAATTTTTGTATTTTTTTTTAATGAAAGGTCTCACATATTTATTACTGAACCCAGCCAACCAATGCATTCATAACAGATTCA GAAAGAAAAAATATATTCCCAATAAAACATGTACAATTCTCCAG >7125_7125_8_ASH2L-CASS4_ASH2L_chr8_37991064_ENST00000428278_CASS4_chr20_55020956_ENST00000371336_length(amino acids)=1107AA_BP=472 MVDVSGGLETESSNGKDTLEGAGDTSEVMDTQAGSVDEENGRQLGEVELQCGICTKWFTADTFGIDTSSCLPFMTNYSFHCNVCHHSGNT YFLRKQANLKEMCLSALANLTWQSRTQDEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMSKERDVFLVKEHPDPGSKD PEEDYPKFGLLDQDLSNIGPAYDNQKQSSAVSTSGNLNGGIAAGSSGKGRGAKRKQQDGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPF NKDGYRYILAEPDPHAPDPEKLELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEIT VDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKS YLYFEEKDFVDKAEKSLKQTPHSEAILTLPRPVRASLPTLPSQVYDVPTQHRGPVVLKEPEKQQLYDIPASPKKAGLHPPDSQASGQGVP LISVTTLRRGGYSTLPNPQKSEWIYDTPVSPGKASVRNTPLTSFAEESRPHALPSSSSTFYNPPSGRSRSLTPQLNNNVPMQKKLSLPEI PSYGFLVPRGTFPLDEDVSYKVPSSFLIPRVEQQNTKPNIYDIPKATSSVSQAGKELEKAKEVSENSAGHNSSWFSRRTTSPSPEPDRLS GSSSDSRASIVSSCSTTSTDDSSSSSSEESAKELSLDLDVAKETVMALQHKVVSSVAGLMLFVSRKWRFRDYLEANIDAIHRSTDHIEES VREFLDFARGVHGTACNLTDSNLQNRIRDQMQTISNSYRILLETKESLDNRNWPLEVLVTDSVQNSPDDLERFVMVARMLPEDIKRFASI VIANGRLLFKRNCEKEETVQLTPNAEFKCEKYIQPPQRETESHQKSTPSTKQREDEHSSELLKKNRANICGQNPGPLIPQPSSQQTPERK PRLSEHCRLYFGALFKAISAFHGSLSSSQPAEIITQSKLVIMVGQKLVDTLCMETQERDVRNEILRGSSHLCSLLKDVALATKNAVLTYP SPAALGHLQAEAEKLEQHTRQFRGTLG -------------------------------------------------------------- >7125_7125_9_ASH2L-CASS4_ASH2L_chr8_37991064_ENST00000428278_CASS4_chr20_55020956_ENST00000434344_length(transcript)=2962nt_BP=1779nt ATCCCGCGGCTCCTGGAGCCCTGCCGCCCGCCCCCTGCGAACCCAGGCCCCGCCGCCAATGGCTCGCCCTGCCTCTGCGCCGCTTGGCCC GTCCCCTCTCAAGCATATCTCGGATAACGCCCCTTCCGCACCTTTCACGGGCGGTGGGAGCTGAGGCTCCTGTCGTTATCTCTGATCCTT GCACCCTGGCAGGAAGCTGGTAGCTCACACTTTAACGGGAGGCCTTCACATATTCCAGAAAAGAAACCACTTTGCAGTGCCAGACTGGAA GAAGTAACGGTCACTCTGAAAACAGGGTGGGAGAGCTGCCTCTCTTTGAACCTCTCCCAGGACCAACTCTAACCCAGGGAGGCAAACTTG GTCGATGTAAGCGGTGGCTTGGAGACAGAATCATCTAATGGAAAAGATACACTAGAAGGTGCTGGGGATACATCAGAGGTGATGGATACT CAGGCGGGCTCCGTGGATGAAGAGAATGGCCGACAGTTGGGTGAGGTAGAGCTGCAATGTGGGATTTGTACAAAATGGTTCACGGCTGAC ACATTTGGCATAGATACCTCATCCTGTCTACCTTTCATGACCAACTACAGTTTTCATTGCAACGTCTGCCATCACAGTGGGAATACCTAT TTCCTCCGGAAGCAAGCAAACTTGAAGGAAATGTGCCTTAGTGCTTTGGCCAACCTGACATGGCAGTCCCGAACACAGGATGAACATCCG AAGACAATGTTCTCCAAAGATAAGGATATTATACCATTTATTGATAAATACTGGGAGTGCATGACAACCAGACAGAGACCTGGGAAAATG ACTTGGCCAAATAACATTGTTAAAACAATGAGTAAAGAAAGAGATGTATTCTTGGTAAAGGAACACCCAGATCCAGGCAGTAAAGATCCA GAAGAAGATTACCCCAAATTTGGACTTTTGGATCAGGACCTTAGTAACATTGGTCCTGCTTATGACAACCAAAAACAGAGCAGTGCTGTG TCTACTAGTGGGAATTTAAATGGGGGAATTGCAGCAGGAAGCAGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACC ACAGGGACCACCAAGAAGGCCCGGAGTGACCCTTTGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAAC AAAGATGGCTATCGGTATATTCTAGCTGAGCCTGATCCGCACGCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCT ATTCCTGGAGACCTCTACAGAGCCTGCTTGTATGAACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGAC CGGCTGACTGTGGTTGGAGAGAAGGGCTACTCTATGGTGAGGGCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTG GATGAGATGCCACCAGATACCGCTGCCAGACTGGGTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGC TATTCTTGGCGGAGCAAAAAGGGAACCAAGTTCCACCAGTCCATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGA TTTTATATTAATCTTCCTGAAGACACAGAGACAGCCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTAT TTGTATTTTGAGGAAAAAGACTTTGTGGATAAAGCAGAGAAGAGCCTGAAGCAGACTCCCCATAGTGAGGCCATCCTCACGCTTCCCAGA CCTGTCCGGGCCTCACTGCCGACTCTGCCTTCCCAGGTGTATGACGTGCCTACCCAGCACCGGGGCCCCGTGGTCCTGAAGGAGCCAGAG AAGCAGCAGTTATATGACATACCAGCCAGCCCCAAGAAGGCAGGACTCCATCCCCCAGACAGCCAAGCAAGTAATCCTGGCCCTCTTATA CCTCAGCCTTCGAGTCAACAGACTCCTGAGAGGAAACCCCGCTTATCTGAACACTGCCGGCTCTACTTTGGGGCGCTCTTCAAAGCCATC AGCGCATTTCACGGCAGCCTCAGCAGCAGCCAGCCCGCGGAGATCATCACTCAGAGCAAGCTGGTCATCATGGTGGGACAGAAGCTGGTG GACACGCTGTGCATGGAGACCCAGGAGAGGGACGTGCGCAACGAGATCCTCCGTGGCAGCAGTCACCTCTGCAGCCTGCTCAAGGACGTA GCGCTGGCCACTAAGAATGCCGTGCTCACGTACCCCAGCCCTGCCGCGCTGGGGCACCTCCAGGCGGAGGCTGAGAAGCTGGAGCAACAC ACGCGGCAGTTCAGAGGGACACTGGGATGAGGACTGTCTACCTCCCTTCCTCCTCTGCTCACCTCTCAGCTTCACACCCACAACTTGTGC AACTCTGCCCTATGGGAAAAGCCAGCCGGGGCATACACCAATGAGCTGAAACAGACCTGGTGCCCAAAGCTGGTAGTACCAAGTGGCTAA GCAACCCCAGGGCATTGACTTACCCCGCAGGGGGTCAGGAAAGAGAGTCAGGTATGAGGTAAAGACCTTGTGAAGTTTAGCATATATGGA GTATGCAGTATCAGCTTGAAGTGACTTCGCAGAAATAATATTTTATATTGATTAAATGTGTGCATGTTTTGTTTGTTTTTTGAGACAAAG TCTCACTCTGTCACACAGGCTGGAGTGCAGTGGCGCGATCTCAGCTCACTGCAACCTCCGCCTTCTGGGTTGAAGCAATTCTCCCGCCTC AGCCTCCAGAGTAGCTGGTACTACAGGTGTGCGCCACCATGCCCAGCTAATTTTTGTATTTTTTTTTAATGAAAGGTCTCACATATTTAT TACTGAACCCAGCCAACCAATGCATTCATAACAGATTCAGAAAGAAAAAATATATTCCCAATAAAACATGTACAATTCTCCA >7125_7125_9_ASH2L-CASS4_ASH2L_chr8_37991064_ENST00000428278_CASS4_chr20_55020956_ENST00000434344_length(amino acids)=670AA_BP=472 MVDVSGGLETESSNGKDTLEGAGDTSEVMDTQAGSVDEENGRQLGEVELQCGICTKWFTADTFGIDTSSCLPFMTNYSFHCNVCHHSGNT YFLRKQANLKEMCLSALANLTWQSRTQDEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMSKERDVFLVKEHPDPGSKD PEEDYPKFGLLDQDLSNIGPAYDNQKQSSAVSTSGNLNGGIAAGSSGKGRGAKRKQQDGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPF NKDGYRYILAEPDPHAPDPEKLELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEIT VDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKS YLYFEEKDFVDKAEKSLKQTPHSEAILTLPRPVRASLPTLPSQVYDVPTQHRGPVVLKEPEKQQLYDIPASPKKAGLHPPDSQASNPGPL IPQPSSQQTPERKPRLSEHCRLYFGALFKAISAFHGSLSSSQPAEIITQSKLVIMVGQKLVDTLCMETQERDVRNEILRGSSHLCSLLKD VALATKNAVLTYPSPAALGHLQAEAEKLEQHTRQFRGTLG -------------------------------------------------------------- >7125_7125_10_ASH2L-CASS4_ASH2L_chr8_37991064_ENST00000521652_CASS4_chr20_55020956_ENST00000360314_length(transcript)=3568nt_BP=1633nt GGAGCTGAGGCTCCTGTCGTTATCTCTGATCCTTGCACCCTGGCAGGAAGCTGGTAGCTCACACTTTAACGGGAGGCCTTCACATATTCC AGAAAAGAAACCACTTTGCAGTGCCAGACTGGAAGAAGTAACGGTCACTCTGAAAACAGGGTGGGAGAGCTGCCTCTCTTTGAACCTCTC CCAGGACCAACTCTAACCCAGGGAGGCAAACTTGGTCGATGTAAGCGGTGGCTTGGAGACAGAATCATCTAATGGAAAAGATACACTAGA AGGTGCTGGGGATACATCAGAGGTGATGGATACTCAGGCGGGCTCCGTGGATGAAGAGAATGGCCGACAGTTGGGTGAGGTAGAGCTGCA ATGTGGGATTTGTACAAAATGGTTCACGGCTGACACATTTGGCATAGATACCTCATCCTGTCTACCTTTCATGACCAACTACAGTTTTCA TTGCAACGTCTGCCATCACAGTGGGAATACCTATTTCCTCCGGAAGCAAGCAAACTTGAAGGAAATGTGCCTTAGTGCTTTGGCCAACCT GACATGGCAGTCCCGAACACAGGATGAACATCCGAAGACAATGTTCTCCAAAGATAAGGATATTATACCATTTATTGATAAATACTGGGA GTGCATGACAACCAGACAGAGACCTGGGAAAATGACTTGGCCAAATAACATTGTTAAAACAATGAGTAAAGAAAGAGATGTATTCTTGGT AAAGGAACACCCAGATCCAGGCAGTAAAGATCCAGAAGAAGATTACCCCAAATTTGGACTTTTGGATCAGGACCTTAGTAACATTGGTCC TGCTTATGACAACCAAAAACAGAGCAGTGCTGTGTCTACTAGTGGGAATTTAAATGGGGGAATTGCAGCAGGAAGCAGCGGAAAAGGACG AGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCACCAAGAAGGCCCGGAGTGACCCTTTGTTTTCTGCTCAGCGCCTTCC CCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGCTATCGGTATATTCTAGCTGAGCCTGATCCGCACGCCCCTGACCCCGA GAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGACCTCTACAGAGCCTGCTTGTATGAACGGGTTTTGTTAGCCCTACA TGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACTGTGGTTGGAGAGAAGGGCTACTCTATGGTGAGGGCCTCTCATGGAGT ACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCCACCAGATACCGCTGCCAGACTGGGTTGGTCCCAGCCCCTAGGAAA CCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGGCGGAGCAAAAAGGGAACCAAGTTCCACCAGTCCATTGGCAAACACTA CTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAATCTTCCTGAAGACACAGAGACAGCCAAGTCATTGCCAGACACATA CAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTTGAGGAAAAAGACTTTGTGGATAAAGCAGAGAAGAGCCTGAAGCAGAC TCCCCATAGTGAGGCCATCCTCACGCTTCCCAGACCTGTCCGGGCCTCACTGCCGACTCTGCCTTCCCAGGTGTATGACGTGCCTACCCA GCACCGGGGCCCCGTGGTCCTGAAGGAGCCAGAGAAGCAGCAGTTATATGACATACCAGCCAGCCCCAAGAAGGCAGGACTCCATCCCCC AGACAGCCAAGCAAGTGGGCAGGGTGTTCCCCTGATATCAGTGACTACCTTAAGAAGAGGCGGTTACAGCACATTACCAAATCCTCAGAA ATCGGAATGGATTTATGACACTCCAGTGTCTCCAGGAAAGGCCAGCGTCAGAAACACGCCTCTCACCAGCTTTGCGGAAGAATCAAGGCC CCACGCTCTCCCCAGTTCCAGCTCCACTTTCTACAATCCTCCAAGTGGCAGATCCAGGTCCCTCACTCCACAACTGAATAACAATGTGCC CATGCAGAAAAAACTCAGCCTTCCAGAAATTCCTTCTTATGGCTTTCTTGTACCCAGAGGCACATTTCCTTTGGATGAAGATGTCAGCTA CAAGGTTCCTTCAAGCTTTCTGATTCCCCGAGTGGAACAGCAGAACACCAAGCCCAATATTTATGACATCCCTAAAGCAACGTCGAGTGT TTCTCAGGCTGGGAAGGAGCTGGAGAAAGCCAAGGAGGTGTCAGAGAATTCCGCGGGCCATAATTCCTCATGGTTCTCCAGACGGACAAC TTCCCCATCTCCTGAACCGGACAGATTATCAGGTTCCAGTTCTGACAGCAGAGCTAGCATCGTTTCCTCGTGCTCCACCACATCCACCGA CGACTCCTCCAGCTCTTCCTCGGAGGAGTCAGCAAAGGAGCTCTCCTTGGACCTGGATGTGGCCAAGGAGACAGTGATGGCTCTGCAGCA CAAGGTGGTCAGCTCTGTCGCTGGCCTGATGCTCTTTGTCAGCAGGAAGTGGAGATTCCGAGACTATCTGGAGGCCAACATTGATGCAAT CCACAGGTCCACTGATCACATAGAAGAATCTGTAAGAGAATTTCTGGATTTTGCCCGAGGAGTCCATGGGACTGCCTGTAACCTCACTGA CAGTAACCTTCAGAACAGAATTCGGGACCAGATGCAGACCATCTCCAACTCCTACCGCATCCTGCTTGAAACAAAGGAAAGCTTGGATAA TCGCAATTGGCCTCTGGAAGTTCTTGTGACTGACAGTGTCCAGAACAGCCCAGATGACCTTGAGAGGTTTGTCATGGTGGCACGGATGCT TCCAGAAGACATCAAGAGGTTTGCCTCCATTGTCATTGCCAATGGAAGGCTCCTTTTTAAGCGGAACTGTGAAAAGGAAGAGACTGTGCA GTTGACCCCAAATGCAGAATTTAAGTGTGAAAAATACATCCAGCCTCCCCAAAGAGAAACTGAATCACACCAAAAGAGTACCCCTTCCAC TAAGCAAAGGGAAGATGAACACTCTTCTGAACTATTAAAGAAAAATAGGGCAAATATCTGTGGACAGAATCCTGGCCCTCTTATACCTCA GCCTTCGAGTCAACAGACTCCTGAGAGGAAACCCCGCTTATCTGAACACTGCCGGCTCTACTTTGGGGCGCTCTTCAAAGCCATCAGCGC ATTTCACGGCAGCCTCAGCAGCAGCCAGCCCGCGGAGATCATCACTCAGAGCAAGCTGGTCATCATGGTGGGACAGAAGCTGGTGGACAC GCTGTGCATGGAGACCCAGGAGAGGGACGTGCGCAACGAGATCCTCCGTGGCAGCAGTCACCTCTGCAGCCTGCTCAAGGACGTAGCGCT GGCCACTAAGAATGCCGTGCTCACGTACCCCAGCCCTGCCGCGCTGGGGCACCTCCAGGCGGAGGCTGAGAAGCTGGAGCAACACACGCG GCAGTTCAGAGGGACACTGGGATGAGGACTGTCTACCTCCCTTCCTCCTCTGCTCACC >7125_7125_10_ASH2L-CASS4_ASH2L_chr8_37991064_ENST00000521652_CASS4_chr20_55020956_ENST00000360314_length(amino acids)=1107AA_BP=472 MVDVSGGLETESSNGKDTLEGAGDTSEVMDTQAGSVDEENGRQLGEVELQCGICTKWFTADTFGIDTSSCLPFMTNYSFHCNVCHHSGNT YFLRKQANLKEMCLSALANLTWQSRTQDEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMSKERDVFLVKEHPDPGSKD PEEDYPKFGLLDQDLSNIGPAYDNQKQSSAVSTSGNLNGGIAAGSSGKGRGAKRKQQDGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPF NKDGYRYILAEPDPHAPDPEKLELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEIT VDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKS YLYFEEKDFVDKAEKSLKQTPHSEAILTLPRPVRASLPTLPSQVYDVPTQHRGPVVLKEPEKQQLYDIPASPKKAGLHPPDSQASGQGVP LISVTTLRRGGYSTLPNPQKSEWIYDTPVSPGKASVRNTPLTSFAEESRPHALPSSSSTFYNPPSGRSRSLTPQLNNNVPMQKKLSLPEI PSYGFLVPRGTFPLDEDVSYKVPSSFLIPRVEQQNTKPNIYDIPKATSSVSQAGKELEKAKEVSENSAGHNSSWFSRRTTSPSPEPDRLS GSSSDSRASIVSSCSTTSTDDSSSSSSEESAKELSLDLDVAKETVMALQHKVVSSVAGLMLFVSRKWRFRDYLEANIDAIHRSTDHIEES VREFLDFARGVHGTACNLTDSNLQNRIRDQMQTISNSYRILLETKESLDNRNWPLEVLVTDSVQNSPDDLERFVMVARMLPEDIKRFASI VIANGRLLFKRNCEKEETVQLTPNAEFKCEKYIQPPQRETESHQKSTPSTKQREDEHSSELLKKNRANICGQNPGPLIPQPSSQQTPERK PRLSEHCRLYFGALFKAISAFHGSLSSSQPAEIITQSKLVIMVGQKLVDTLCMETQERDVRNEILRGSSHLCSLLKDVALATKNAVLTYP SPAALGHLQAEAEKLEQHTRQFRGTLG -------------------------------------------------------------- >7125_7125_11_ASH2L-CASS4_ASH2L_chr8_37991064_ENST00000521652_CASS4_chr20_55020956_ENST00000371336_length(transcript)=4128nt_BP=1633nt GGAGCTGAGGCTCCTGTCGTTATCTCTGATCCTTGCACCCTGGCAGGAAGCTGGTAGCTCACACTTTAACGGGAGGCCTTCACATATTCC AGAAAAGAAACCACTTTGCAGTGCCAGACTGGAAGAAGTAACGGTCACTCTGAAAACAGGGTGGGAGAGCTGCCTCTCTTTGAACCTCTC CCAGGACCAACTCTAACCCAGGGAGGCAAACTTGGTCGATGTAAGCGGTGGCTTGGAGACAGAATCATCTAATGGAAAAGATACACTAGA AGGTGCTGGGGATACATCAGAGGTGATGGATACTCAGGCGGGCTCCGTGGATGAAGAGAATGGCCGACAGTTGGGTGAGGTAGAGCTGCA ATGTGGGATTTGTACAAAATGGTTCACGGCTGACACATTTGGCATAGATACCTCATCCTGTCTACCTTTCATGACCAACTACAGTTTTCA TTGCAACGTCTGCCATCACAGTGGGAATACCTATTTCCTCCGGAAGCAAGCAAACTTGAAGGAAATGTGCCTTAGTGCTTTGGCCAACCT GACATGGCAGTCCCGAACACAGGATGAACATCCGAAGACAATGTTCTCCAAAGATAAGGATATTATACCATTTATTGATAAATACTGGGA GTGCATGACAACCAGACAGAGACCTGGGAAAATGACTTGGCCAAATAACATTGTTAAAACAATGAGTAAAGAAAGAGATGTATTCTTGGT AAAGGAACACCCAGATCCAGGCAGTAAAGATCCAGAAGAAGATTACCCCAAATTTGGACTTTTGGATCAGGACCTTAGTAACATTGGTCC TGCTTATGACAACCAAAAACAGAGCAGTGCTGTGTCTACTAGTGGGAATTTAAATGGGGGAATTGCAGCAGGAAGCAGCGGAAAAGGACG AGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCACCAAGAAGGCCCGGAGTGACCCTTTGTTTTCTGCTCAGCGCCTTCC CCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGCTATCGGTATATTCTAGCTGAGCCTGATCCGCACGCCCCTGACCCCGA GAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGACCTCTACAGAGCCTGCTTGTATGAACGGGTTTTGTTAGCCCTACA TGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACTGTGGTTGGAGAGAAGGGCTACTCTATGGTGAGGGCCTCTCATGGAGT ACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCCACCAGATACCGCTGCCAGACTGGGTTGGTCCCAGCCCCTAGGAAA CCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGGCGGAGCAAAAAGGGAACCAAGTTCCACCAGTCCATTGGCAAACACTA CTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAATCTTCCTGAAGACACAGAGACAGCCAAGTCATTGCCAGACACATA CAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTTGAGGAAAAAGACTTTGTGGATAAAGCAGAGAAGAGCCTGAAGCAGAC TCCCCATAGTGAGGCCATCCTCACGCTTCCCAGACCTGTCCGGGCCTCACTGCCGACTCTGCCTTCCCAGGTGTATGACGTGCCTACCCA GCACCGGGGCCCCGTGGTCCTGAAGGAGCCAGAGAAGCAGCAGTTATATGACATACCAGCCAGCCCCAAGAAGGCAGGACTCCATCCCCC AGACAGCCAAGCAAGTGGGCAGGGTGTTCCCCTGATATCAGTGACTACCTTAAGAAGAGGCGGTTACAGCACATTACCAAATCCTCAGAA ATCGGAATGGATTTATGACACTCCAGTGTCTCCAGGAAAGGCCAGCGTCAGAAACACGCCTCTCACCAGCTTTGCGGAAGAATCAAGGCC CCACGCTCTCCCCAGTTCCAGCTCCACTTTCTACAATCCTCCAAGTGGCAGATCCAGGTCCCTCACTCCACAACTGAATAACAATGTGCC CATGCAGAAAAAACTCAGCCTTCCAGAAATTCCTTCTTATGGCTTTCTTGTACCCAGAGGCACATTTCCTTTGGATGAAGATGTCAGCTA CAAGGTTCCTTCAAGCTTTCTGATTCCCCGAGTGGAACAGCAGAACACCAAGCCCAATATTTATGACATCCCTAAAGCAACGTCGAGTGT TTCTCAGGCTGGGAAGGAGCTGGAGAAAGCCAAGGAGGTGTCAGAGAATTCCGCGGGCCATAATTCCTCATGGTTCTCCAGACGGACAAC TTCCCCATCTCCTGAACCGGACAGATTATCAGGTTCCAGTTCTGACAGCAGAGCTAGCATCGTTTCCTCGTGCTCCACCACATCCACCGA CGACTCCTCCAGCTCTTCCTCGGAGGAGTCAGCAAAGGAGCTCTCCTTGGACCTGGATGTGGCCAAGGAGACAGTGATGGCTCTGCAGCA CAAGGTGGTCAGCTCTGTCGCTGGCCTGATGCTCTTTGTCAGCAGGAAGTGGAGATTCCGAGACTATCTGGAGGCCAACATTGATGCAAT CCACAGGTCCACTGATCACATAGAAGAATCTGTAAGAGAATTTCTGGATTTTGCCCGAGGAGTCCATGGGACTGCCTGTAACCTCACTGA CAGTAACCTTCAGAACAGAATTCGGGACCAGATGCAGACCATCTCCAACTCCTACCGCATCCTGCTTGAAACAAAGGAAAGCTTGGATAA TCGCAATTGGCCTCTGGAAGTTCTTGTGACTGACAGTGTCCAGAACAGCCCAGATGACCTTGAGAGGTTTGTCATGGTGGCACGGATGCT TCCAGAAGACATCAAGAGGTTTGCCTCCATTGTCATTGCCAATGGAAGGCTCCTTTTTAAGCGGAACTGTGAAAAGGAAGAGACTGTGCA GTTGACCCCAAATGCAGAATTTAAGTGTGAAAAATACATCCAGCCTCCCCAAAGAGAAACTGAATCACACCAAAAGAGTACCCCTTCCAC TAAGCAAAGGGAAGATGAACACTCTTCTGAACTATTAAAGAAAAATAGGGCAAATATCTGTGGACAGAATCCTGGCCCTCTTATACCTCA GCCTTCGAGTCAACAGACTCCTGAGAGGAAACCCCGCTTATCTGAACACTGCCGGCTCTACTTTGGGGCGCTCTTCAAAGCCATCAGCGC ATTTCACGGCAGCCTCAGCAGCAGCCAGCCCGCGGAGATCATCACTCAGAGCAAGCTGGTCATCATGGTGGGACAGAAGCTGGTGGACAC GCTGTGCATGGAGACCCAGGAGAGGGACGTGCGCAACGAGATCCTCCGTGGCAGCAGTCACCTCTGCAGCCTGCTCAAGGACGTAGCGCT GGCCACTAAGAATGCCGTGCTCACGTACCCCAGCCCTGCCGCGCTGGGGCACCTCCAGGCGGAGGCTGAGAAGCTGGAGCAACACACGCG GCAGTTCAGAGGGACACTGGGATGAGGACTGTCTACCTCCCTTCCTCCTCTGCTCACCTCTCAGCTTCACACCCACAACTTGTGCAACTC TGCCCTATGGGAAAAGCCAGCCGGGGCATACACCAATGAGCTGAAACAGACCTGGTGCCCAAAGCTGGTAGTACCAAGTGGCTAAGCAAC CCCAGGGCATTGACTTACCCCGCAGGGGGTCAGGAAAGAGAGTCAGGTATGAGGTAAAGACCTTGTGAAGTTTAGCATATATGGAGTATG CAGTATCAGCTTGAAGTGACTTCGCAGAAATAATATTTTATATTGATTAAATGTGTGCATGTTTTGTTTGTTTTTTGAGACAAAGTCTCA CTCTGTCACACAGGCTGGAGTGCAGTGGCGCGATCTCAGCTCACTGCAACCTCCGCCTTCTGGGTTGAAGCAATTCTCCCGCCTCAGCCT CCAGAGTAGCTGGTACTACAGGTGTGCGCCACCATGCCCAGCTAATTTTTGTATTTTTTTTTAATGAAAGGTCTCACATATTTATTACTG AACCCAGCCAACCAATGCATTCATAACAGATTCAGAAAGAAAAAATATATTCCCAATAAAACATGTACAATTCTCCAG >7125_7125_11_ASH2L-CASS4_ASH2L_chr8_37991064_ENST00000521652_CASS4_chr20_55020956_ENST00000371336_length(amino acids)=1107AA_BP=472 MVDVSGGLETESSNGKDTLEGAGDTSEVMDTQAGSVDEENGRQLGEVELQCGICTKWFTADTFGIDTSSCLPFMTNYSFHCNVCHHSGNT YFLRKQANLKEMCLSALANLTWQSRTQDEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMSKERDVFLVKEHPDPGSKD PEEDYPKFGLLDQDLSNIGPAYDNQKQSSAVSTSGNLNGGIAAGSSGKGRGAKRKQQDGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPF NKDGYRYILAEPDPHAPDPEKLELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEIT VDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKS YLYFEEKDFVDKAEKSLKQTPHSEAILTLPRPVRASLPTLPSQVYDVPTQHRGPVVLKEPEKQQLYDIPASPKKAGLHPPDSQASGQGVP LISVTTLRRGGYSTLPNPQKSEWIYDTPVSPGKASVRNTPLTSFAEESRPHALPSSSSTFYNPPSGRSRSLTPQLNNNVPMQKKLSLPEI PSYGFLVPRGTFPLDEDVSYKVPSSFLIPRVEQQNTKPNIYDIPKATSSVSQAGKELEKAKEVSENSAGHNSSWFSRRTTSPSPEPDRLS GSSSDSRASIVSSCSTTSTDDSSSSSSEESAKELSLDLDVAKETVMALQHKVVSSVAGLMLFVSRKWRFRDYLEANIDAIHRSTDHIEES VREFLDFARGVHGTACNLTDSNLQNRIRDQMQTISNSYRILLETKESLDNRNWPLEVLVTDSVQNSPDDLERFVMVARMLPEDIKRFASI VIANGRLLFKRNCEKEETVQLTPNAEFKCEKYIQPPQRETESHQKSTPSTKQREDEHSSELLKKNRANICGQNPGPLIPQPSSQQTPERK PRLSEHCRLYFGALFKAISAFHGSLSSSQPAEIITQSKLVIMVGQKLVDTLCMETQERDVRNEILRGSSHLCSLLKDVALATKNAVLTYP SPAALGHLQAEAEKLEQHTRQFRGTLG -------------------------------------------------------------- >7125_7125_12_ASH2L-CASS4_ASH2L_chr8_37991064_ENST00000521652_CASS4_chr20_55020956_ENST00000434344_length(transcript)=2816nt_BP=1633nt GGAGCTGAGGCTCCTGTCGTTATCTCTGATCCTTGCACCCTGGCAGGAAGCTGGTAGCTCACACTTTAACGGGAGGCCTTCACATATTCC AGAAAAGAAACCACTTTGCAGTGCCAGACTGGAAGAAGTAACGGTCACTCTGAAAACAGGGTGGGAGAGCTGCCTCTCTTTGAACCTCTC CCAGGACCAACTCTAACCCAGGGAGGCAAACTTGGTCGATGTAAGCGGTGGCTTGGAGACAGAATCATCTAATGGAAAAGATACACTAGA AGGTGCTGGGGATACATCAGAGGTGATGGATACTCAGGCGGGCTCCGTGGATGAAGAGAATGGCCGACAGTTGGGTGAGGTAGAGCTGCA ATGTGGGATTTGTACAAAATGGTTCACGGCTGACACATTTGGCATAGATACCTCATCCTGTCTACCTTTCATGACCAACTACAGTTTTCA TTGCAACGTCTGCCATCACAGTGGGAATACCTATTTCCTCCGGAAGCAAGCAAACTTGAAGGAAATGTGCCTTAGTGCTTTGGCCAACCT GACATGGCAGTCCCGAACACAGGATGAACATCCGAAGACAATGTTCTCCAAAGATAAGGATATTATACCATTTATTGATAAATACTGGGA GTGCATGACAACCAGACAGAGACCTGGGAAAATGACTTGGCCAAATAACATTGTTAAAACAATGAGTAAAGAAAGAGATGTATTCTTGGT AAAGGAACACCCAGATCCAGGCAGTAAAGATCCAGAAGAAGATTACCCCAAATTTGGACTTTTGGATCAGGACCTTAGTAACATTGGTCC TGCTTATGACAACCAAAAACAGAGCAGTGCTGTGTCTACTAGTGGGAATTTAAATGGGGGAATTGCAGCAGGAAGCAGCGGAAAAGGACG AGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCACCAAGAAGGCCCGGAGTGACCCTTTGTTTTCTGCTCAGCGCCTTCC CCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGCTATCGGTATATTCTAGCTGAGCCTGATCCGCACGCCCCTGACCCCGA GAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGACCTCTACAGAGCCTGCTTGTATGAACGGGTTTTGTTAGCCCTACA TGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACTGTGGTTGGAGAGAAGGGCTACTCTATGGTGAGGGCCTCTCATGGAGT ACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCCACCAGATACCGCTGCCAGACTGGGTTGGTCCCAGCCCCTAGGAAA CCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGGCGGAGCAAAAAGGGAACCAAGTTCCACCAGTCCATTGGCAAACACTA CTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAATCTTCCTGAAGACACAGAGACAGCCAAGTCATTGCCAGACACATA CAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTTGAGGAAAAAGACTTTGTGGATAAAGCAGAGAAGAGCCTGAAGCAGAC TCCCCATAGTGAGGCCATCCTCACGCTTCCCAGACCTGTCCGGGCCTCACTGCCGACTCTGCCTTCCCAGGTGTATGACGTGCCTACCCA GCACCGGGGCCCCGTGGTCCTGAAGGAGCCAGAGAAGCAGCAGTTATATGACATACCAGCCAGCCCCAAGAAGGCAGGACTCCATCCCCC AGACAGCCAAGCAAGTAATCCTGGCCCTCTTATACCTCAGCCTTCGAGTCAACAGACTCCTGAGAGGAAACCCCGCTTATCTGAACACTG CCGGCTCTACTTTGGGGCGCTCTTCAAAGCCATCAGCGCATTTCACGGCAGCCTCAGCAGCAGCCAGCCCGCGGAGATCATCACTCAGAG CAAGCTGGTCATCATGGTGGGACAGAAGCTGGTGGACACGCTGTGCATGGAGACCCAGGAGAGGGACGTGCGCAACGAGATCCTCCGTGG CAGCAGTCACCTCTGCAGCCTGCTCAAGGACGTAGCGCTGGCCACTAAGAATGCCGTGCTCACGTACCCCAGCCCTGCCGCGCTGGGGCA CCTCCAGGCGGAGGCTGAGAAGCTGGAGCAACACACGCGGCAGTTCAGAGGGACACTGGGATGAGGACTGTCTACCTCCCTTCCTCCTCT GCTCACCTCTCAGCTTCACACCCACAACTTGTGCAACTCTGCCCTATGGGAAAAGCCAGCCGGGGCATACACCAATGAGCTGAAACAGAC CTGGTGCCCAAAGCTGGTAGTACCAAGTGGCTAAGCAACCCCAGGGCATTGACTTACCCCGCAGGGGGTCAGGAAAGAGAGTCAGGTATG AGGTAAAGACCTTGTGAAGTTTAGCATATATGGAGTATGCAGTATCAGCTTGAAGTGACTTCGCAGAAATAATATTTTATATTGATTAAA TGTGTGCATGTTTTGTTTGTTTTTTGAGACAAAGTCTCACTCTGTCACACAGGCTGGAGTGCAGTGGCGCGATCTCAGCTCACTGCAACC TCCGCCTTCTGGGTTGAAGCAATTCTCCCGCCTCAGCCTCCAGAGTAGCTGGTACTACAGGTGTGCGCCACCATGCCCAGCTAATTTTTG TATTTTTTTTTAATGAAAGGTCTCACATATTTATTACTGAACCCAGCCAACCAATGCATTCATAACAGATTCAGAAAGAAAAAATATATT CCCAATAAAACATGTACAATTCTCCA >7125_7125_12_ASH2L-CASS4_ASH2L_chr8_37991064_ENST00000521652_CASS4_chr20_55020956_ENST00000434344_length(amino acids)=670AA_BP=472 MVDVSGGLETESSNGKDTLEGAGDTSEVMDTQAGSVDEENGRQLGEVELQCGICTKWFTADTFGIDTSSCLPFMTNYSFHCNVCHHSGNT YFLRKQANLKEMCLSALANLTWQSRTQDEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMSKERDVFLVKEHPDPGSKD PEEDYPKFGLLDQDLSNIGPAYDNQKQSSAVSTSGNLNGGIAAGSSGKGRGAKRKQQDGGTTGTTKKARSDPLFSAQRLPPHGYPLEHPF NKDGYRYILAEPDPHAPDPEKLELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEIT VDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETAKSLPDTYKDKALIKFKS YLYFEEKDFVDKAEKSLKQTPHSEAILTLPRPVRASLPTLPSQVYDVPTQHRGPVVLKEPEKQQLYDIPASPKKAGLHPPDSQASNPGPL IPQPSSQQTPERKPRLSEHCRLYFGALFKAISAFHGSLSSSQPAEIITQSKLVIMVGQKLVDTLCMETQERDVRNEILRGSSHLCSLLKD VALATKNAVLTYPSPAALGHLQAEAEKLEQHTRQFRGTLG -------------------------------------------------------------- >7125_7125_13_ASH2L-CASS4_ASH2L_chr8_37991064_ENST00000545394_CASS4_chr20_55020956_ENST00000360314_length(transcript)=3410nt_BP=1475nt GATGGCGGCGGCAGGAGCAGGACCTGGCCAGGAAGCGGGTGCCGGGCCTGGCCCAGGAGCGGTCGCAAATGCAACAGGGGCAGAAGAGGG GGAGATGAAGCCGGTGGCAGCGGGAGCAGCCGCTCCTCCTGGAGAGGGGATCTCTGCTGCTCCGACAGTTGAGCCCAGTTCCGGGGAGGC TGAAGGCGGGGAGGCAAACTTGGTCGATGTAAGCGGTGGCTTGGAGACAGAATCATCTAATGGAAAAGATACACTAATCCTGTCTACCTT TCATGACCAACTACAGTTTTCATTGCAACGTCTGCCATCACAGTGGGAATACCTATTTCCTCCGGAAGCAAGCAAACTTGAAGGAAATGT GCCTTAGTGCTTTGGCCAACCTGACATGGCAGTCCCGAACACAGGATGAACATCCGAAGACAATGTTCTCCAAAGATAAGGATATTATAC CATTTATTGATAAATACTGGGAGTGCATGACAACCAGACAGAGACCTGGGAAAATGACTTGGCCAAATAACATTGTTAAAACAATGAGTA AAGAAAGAGATGTATTCTTGGTAAAGGAACACCCAGATCCAGGCAGTAAAGATCCAGAAGAAGATTACCCCAAATTTGGACTTTTGGATC AGGACCTTAGTAACATTGGTCCTGCTTATGACAACCAAAAACAGAGCAGTGCTGTGTCTACTAGTGGGAATTTAAATGGGGGAATTGCAG CAGGAAGCAGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCACCAAGAAGGCCCGGAGTGACCCTT TGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGCTATCGGTATATTCTAGCTGAGCCTG ATCCGCACGCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGACCTCTACAGAGCCTGCTTGTATG AACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACTGTGGTTGGAGAGAAGGGCTACTCTA TGGTGAGGGCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCCACCAGATACCGCTGCCAGACTGG GTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGGCGGAGCAAAAAGGGAACCAAGTTCC ACCAGTCCATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAATCTTCCTGAAGACACAGAGACAG CCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTTGAGGAAAAAGACTTTGTGGATAAAG CAGAGAAGAGCCTGAAGCAGACTCCCCATAGTGAGGCCATCCTCACGCTTCCCAGACCTGTCCGGGCCTCACTGCCGACTCTGCCTTCCC AGGTGTATGACGTGCCTACCCAGCACCGGGGCCCCGTGGTCCTGAAGGAGCCAGAGAAGCAGCAGTTATATGACATACCAGCCAGCCCCA AGAAGGCAGGACTCCATCCCCCAGACAGCCAAGCAAGTGGGCAGGGTGTTCCCCTGATATCAGTGACTACCTTAAGAAGAGGCGGTTACA GCACATTACCAAATCCTCAGAAATCGGAATGGATTTATGACACTCCAGTGTCTCCAGGAAAGGCCAGCGTCAGAAACACGCCTCTCACCA GCTTTGCGGAAGAATCAAGGCCCCACGCTCTCCCCAGTTCCAGCTCCACTTTCTACAATCCTCCAAGTGGCAGATCCAGGTCCCTCACTC CACAACTGAATAACAATGTGCCCATGCAGAAAAAACTCAGCCTTCCAGAAATTCCTTCTTATGGCTTTCTTGTACCCAGAGGCACATTTC CTTTGGATGAAGATGTCAGCTACAAGGTTCCTTCAAGCTTTCTGATTCCCCGAGTGGAACAGCAGAACACCAAGCCCAATATTTATGACA TCCCTAAAGCAACGTCGAGTGTTTCTCAGGCTGGGAAGGAGCTGGAGAAAGCCAAGGAGGTGTCAGAGAATTCCGCGGGCCATAATTCCT CATGGTTCTCCAGACGGACAACTTCCCCATCTCCTGAACCGGACAGATTATCAGGTTCCAGTTCTGACAGCAGAGCTAGCATCGTTTCCT CGTGCTCCACCACATCCACCGACGACTCCTCCAGCTCTTCCTCGGAGGAGTCAGCAAAGGAGCTCTCCTTGGACCTGGATGTGGCCAAGG AGACAGTGATGGCTCTGCAGCACAAGGTGGTCAGCTCTGTCGCTGGCCTGATGCTCTTTGTCAGCAGGAAGTGGAGATTCCGAGACTATC TGGAGGCCAACATTGATGCAATCCACAGGTCCACTGATCACATAGAAGAATCTGTAAGAGAATTTCTGGATTTTGCCCGAGGAGTCCATG GGACTGCCTGTAACCTCACTGACAGTAACCTTCAGAACAGAATTCGGGACCAGATGCAGACCATCTCCAACTCCTACCGCATCCTGCTTG AAACAAAGGAAAGCTTGGATAATCGCAATTGGCCTCTGGAAGTTCTTGTGACTGACAGTGTCCAGAACAGCCCAGATGACCTTGAGAGGT TTGTCATGGTGGCACGGATGCTTCCAGAAGACATCAAGAGGTTTGCCTCCATTGTCATTGCCAATGGAAGGCTCCTTTTTAAGCGGAACT GTGAAAAGGAAGAGACTGTGCAGTTGACCCCAAATGCAGAATTTAAGTGTGAAAAATACATCCAGCCTCCCCAAAGAGAAACTGAATCAC ACCAAAAGAGTACCCCTTCCACTAAGCAAAGGGAAGATGAACACTCTTCTGAACTATTAAAGAAAAATAGGGCAAATATCTGTGGACAGA ATCCTGGCCCTCTTATACCTCAGCCTTCGAGTCAACAGACTCCTGAGAGGAAACCCCGCTTATCTGAACACTGCCGGCTCTACTTTGGGG CGCTCTTCAAAGCCATCAGCGCATTTCACGGCAGCCTCAGCAGCAGCCAGCCCGCGGAGATCATCACTCAGAGCAAGCTGGTCATCATGG TGGGACAGAAGCTGGTGGACACGCTGTGCATGGAGACCCAGGAGAGGGACGTGCGCAACGAGATCCTCCGTGGCAGCAGTCACCTCTGCA GCCTGCTCAAGGACGTAGCGCTGGCCACTAAGAATGCCGTGCTCACGTACCCCAGCCCTGCCGCGCTGGGGCACCTCCAGGCGGAGGCTG AGAAGCTGGAGCAACACACGCGGCAGTTCAGAGGGACACTGGGATGAGGACTGTCTACCTCCCTTCCTCCTCTGCTCACC >7125_7125_13_ASH2L-CASS4_ASH2L_chr8_37991064_ENST00000545394_CASS4_chr20_55020956_ENST00000360314_length(amino acids)=1034AA_BP=399 MTNYSFHCNVCHHSGNTYFLRKQANLKEMCLSALANLTWQSRTQDEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMSK ERDVFLVKEHPDPGSKDPEEDYPKFGLLDQDLSNIGPAYDNQKQSSAVSTSGNLNGGIAAGSSGKGRGAKRKQQDGGTTGTTKKARSDPL FSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSM VRASHGVRKGAWYFEITVDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETA KSLPDTYKDKALIKFKSYLYFEEKDFVDKAEKSLKQTPHSEAILTLPRPVRASLPTLPSQVYDVPTQHRGPVVLKEPEKQQLYDIPASPK KAGLHPPDSQASGQGVPLISVTTLRRGGYSTLPNPQKSEWIYDTPVSPGKASVRNTPLTSFAEESRPHALPSSSSTFYNPPSGRSRSLTP QLNNNVPMQKKLSLPEIPSYGFLVPRGTFPLDEDVSYKVPSSFLIPRVEQQNTKPNIYDIPKATSSVSQAGKELEKAKEVSENSAGHNSS WFSRRTTSPSPEPDRLSGSSSDSRASIVSSCSTTSTDDSSSSSSEESAKELSLDLDVAKETVMALQHKVVSSVAGLMLFVSRKWRFRDYL EANIDAIHRSTDHIEESVREFLDFARGVHGTACNLTDSNLQNRIRDQMQTISNSYRILLETKESLDNRNWPLEVLVTDSVQNSPDDLERF VMVARMLPEDIKRFASIVIANGRLLFKRNCEKEETVQLTPNAEFKCEKYIQPPQRETESHQKSTPSTKQREDEHSSELLKKNRANICGQN PGPLIPQPSSQQTPERKPRLSEHCRLYFGALFKAISAFHGSLSSSQPAEIITQSKLVIMVGQKLVDTLCMETQERDVRNEILRGSSHLCS LLKDVALATKNAVLTYPSPAALGHLQAEAEKLEQHTRQFRGTLG -------------------------------------------------------------- >7125_7125_14_ASH2L-CASS4_ASH2L_chr8_37991064_ENST00000545394_CASS4_chr20_55020956_ENST00000371336_length(transcript)=3970nt_BP=1475nt GATGGCGGCGGCAGGAGCAGGACCTGGCCAGGAAGCGGGTGCCGGGCCTGGCCCAGGAGCGGTCGCAAATGCAACAGGGGCAGAAGAGGG GGAGATGAAGCCGGTGGCAGCGGGAGCAGCCGCTCCTCCTGGAGAGGGGATCTCTGCTGCTCCGACAGTTGAGCCCAGTTCCGGGGAGGC TGAAGGCGGGGAGGCAAACTTGGTCGATGTAAGCGGTGGCTTGGAGACAGAATCATCTAATGGAAAAGATACACTAATCCTGTCTACCTT TCATGACCAACTACAGTTTTCATTGCAACGTCTGCCATCACAGTGGGAATACCTATTTCCTCCGGAAGCAAGCAAACTTGAAGGAAATGT GCCTTAGTGCTTTGGCCAACCTGACATGGCAGTCCCGAACACAGGATGAACATCCGAAGACAATGTTCTCCAAAGATAAGGATATTATAC CATTTATTGATAAATACTGGGAGTGCATGACAACCAGACAGAGACCTGGGAAAATGACTTGGCCAAATAACATTGTTAAAACAATGAGTA AAGAAAGAGATGTATTCTTGGTAAAGGAACACCCAGATCCAGGCAGTAAAGATCCAGAAGAAGATTACCCCAAATTTGGACTTTTGGATC AGGACCTTAGTAACATTGGTCCTGCTTATGACAACCAAAAACAGAGCAGTGCTGTGTCTACTAGTGGGAATTTAAATGGGGGAATTGCAG CAGGAAGCAGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCACCAAGAAGGCCCGGAGTGACCCTT TGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGCTATCGGTATATTCTAGCTGAGCCTG ATCCGCACGCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGACCTCTACAGAGCCTGCTTGTATG AACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACTGTGGTTGGAGAGAAGGGCTACTCTA TGGTGAGGGCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCCACCAGATACCGCTGCCAGACTGG GTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGGCGGAGCAAAAAGGGAACCAAGTTCC ACCAGTCCATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAATCTTCCTGAAGACACAGAGACAG CCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTTGAGGAAAAAGACTTTGTGGATAAAG CAGAGAAGAGCCTGAAGCAGACTCCCCATAGTGAGGCCATCCTCACGCTTCCCAGACCTGTCCGGGCCTCACTGCCGACTCTGCCTTCCC AGGTGTATGACGTGCCTACCCAGCACCGGGGCCCCGTGGTCCTGAAGGAGCCAGAGAAGCAGCAGTTATATGACATACCAGCCAGCCCCA AGAAGGCAGGACTCCATCCCCCAGACAGCCAAGCAAGTGGGCAGGGTGTTCCCCTGATATCAGTGACTACCTTAAGAAGAGGCGGTTACA GCACATTACCAAATCCTCAGAAATCGGAATGGATTTATGACACTCCAGTGTCTCCAGGAAAGGCCAGCGTCAGAAACACGCCTCTCACCA GCTTTGCGGAAGAATCAAGGCCCCACGCTCTCCCCAGTTCCAGCTCCACTTTCTACAATCCTCCAAGTGGCAGATCCAGGTCCCTCACTC CACAACTGAATAACAATGTGCCCATGCAGAAAAAACTCAGCCTTCCAGAAATTCCTTCTTATGGCTTTCTTGTACCCAGAGGCACATTTC CTTTGGATGAAGATGTCAGCTACAAGGTTCCTTCAAGCTTTCTGATTCCCCGAGTGGAACAGCAGAACACCAAGCCCAATATTTATGACA TCCCTAAAGCAACGTCGAGTGTTTCTCAGGCTGGGAAGGAGCTGGAGAAAGCCAAGGAGGTGTCAGAGAATTCCGCGGGCCATAATTCCT CATGGTTCTCCAGACGGACAACTTCCCCATCTCCTGAACCGGACAGATTATCAGGTTCCAGTTCTGACAGCAGAGCTAGCATCGTTTCCT CGTGCTCCACCACATCCACCGACGACTCCTCCAGCTCTTCCTCGGAGGAGTCAGCAAAGGAGCTCTCCTTGGACCTGGATGTGGCCAAGG AGACAGTGATGGCTCTGCAGCACAAGGTGGTCAGCTCTGTCGCTGGCCTGATGCTCTTTGTCAGCAGGAAGTGGAGATTCCGAGACTATC TGGAGGCCAACATTGATGCAATCCACAGGTCCACTGATCACATAGAAGAATCTGTAAGAGAATTTCTGGATTTTGCCCGAGGAGTCCATG GGACTGCCTGTAACCTCACTGACAGTAACCTTCAGAACAGAATTCGGGACCAGATGCAGACCATCTCCAACTCCTACCGCATCCTGCTTG AAACAAAGGAAAGCTTGGATAATCGCAATTGGCCTCTGGAAGTTCTTGTGACTGACAGTGTCCAGAACAGCCCAGATGACCTTGAGAGGT TTGTCATGGTGGCACGGATGCTTCCAGAAGACATCAAGAGGTTTGCCTCCATTGTCATTGCCAATGGAAGGCTCCTTTTTAAGCGGAACT GTGAAAAGGAAGAGACTGTGCAGTTGACCCCAAATGCAGAATTTAAGTGTGAAAAATACATCCAGCCTCCCCAAAGAGAAACTGAATCAC ACCAAAAGAGTACCCCTTCCACTAAGCAAAGGGAAGATGAACACTCTTCTGAACTATTAAAGAAAAATAGGGCAAATATCTGTGGACAGA ATCCTGGCCCTCTTATACCTCAGCCTTCGAGTCAACAGACTCCTGAGAGGAAACCCCGCTTATCTGAACACTGCCGGCTCTACTTTGGGG CGCTCTTCAAAGCCATCAGCGCATTTCACGGCAGCCTCAGCAGCAGCCAGCCCGCGGAGATCATCACTCAGAGCAAGCTGGTCATCATGG TGGGACAGAAGCTGGTGGACACGCTGTGCATGGAGACCCAGGAGAGGGACGTGCGCAACGAGATCCTCCGTGGCAGCAGTCACCTCTGCA GCCTGCTCAAGGACGTAGCGCTGGCCACTAAGAATGCCGTGCTCACGTACCCCAGCCCTGCCGCGCTGGGGCACCTCCAGGCGGAGGCTG AGAAGCTGGAGCAACACACGCGGCAGTTCAGAGGGACACTGGGATGAGGACTGTCTACCTCCCTTCCTCCTCTGCTCACCTCTCAGCTTC ACACCCACAACTTGTGCAACTCTGCCCTATGGGAAAAGCCAGCCGGGGCATACACCAATGAGCTGAAACAGACCTGGTGCCCAAAGCTGG TAGTACCAAGTGGCTAAGCAACCCCAGGGCATTGACTTACCCCGCAGGGGGTCAGGAAAGAGAGTCAGGTATGAGGTAAAGACCTTGTGA AGTTTAGCATATATGGAGTATGCAGTATCAGCTTGAAGTGACTTCGCAGAAATAATATTTTATATTGATTAAATGTGTGCATGTTTTGTT TGTTTTTTGAGACAAAGTCTCACTCTGTCACACAGGCTGGAGTGCAGTGGCGCGATCTCAGCTCACTGCAACCTCCGCCTTCTGGGTTGA AGCAATTCTCCCGCCTCAGCCTCCAGAGTAGCTGGTACTACAGGTGTGCGCCACCATGCCCAGCTAATTTTTGTATTTTTTTTTAATGAA AGGTCTCACATATTTATTACTGAACCCAGCCAACCAATGCATTCATAACAGATTCAGAAAGAAAAAATATATTCCCAATAAAACATGTAC AATTCTCCAG >7125_7125_14_ASH2L-CASS4_ASH2L_chr8_37991064_ENST00000545394_CASS4_chr20_55020956_ENST00000371336_length(amino acids)=1034AA_BP=399 MTNYSFHCNVCHHSGNTYFLRKQANLKEMCLSALANLTWQSRTQDEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMSK ERDVFLVKEHPDPGSKDPEEDYPKFGLLDQDLSNIGPAYDNQKQSSAVSTSGNLNGGIAAGSSGKGRGAKRKQQDGGTTGTTKKARSDPL FSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSM VRASHGVRKGAWYFEITVDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETA KSLPDTYKDKALIKFKSYLYFEEKDFVDKAEKSLKQTPHSEAILTLPRPVRASLPTLPSQVYDVPTQHRGPVVLKEPEKQQLYDIPASPK KAGLHPPDSQASGQGVPLISVTTLRRGGYSTLPNPQKSEWIYDTPVSPGKASVRNTPLTSFAEESRPHALPSSSSTFYNPPSGRSRSLTP QLNNNVPMQKKLSLPEIPSYGFLVPRGTFPLDEDVSYKVPSSFLIPRVEQQNTKPNIYDIPKATSSVSQAGKELEKAKEVSENSAGHNSS WFSRRTTSPSPEPDRLSGSSSDSRASIVSSCSTTSTDDSSSSSSEESAKELSLDLDVAKETVMALQHKVVSSVAGLMLFVSRKWRFRDYL EANIDAIHRSTDHIEESVREFLDFARGVHGTACNLTDSNLQNRIRDQMQTISNSYRILLETKESLDNRNWPLEVLVTDSVQNSPDDLERF VMVARMLPEDIKRFASIVIANGRLLFKRNCEKEETVQLTPNAEFKCEKYIQPPQRETESHQKSTPSTKQREDEHSSELLKKNRANICGQN PGPLIPQPSSQQTPERKPRLSEHCRLYFGALFKAISAFHGSLSSSQPAEIITQSKLVIMVGQKLVDTLCMETQERDVRNEILRGSSHLCS LLKDVALATKNAVLTYPSPAALGHLQAEAEKLEQHTRQFRGTLG -------------------------------------------------------------- >7125_7125_15_ASH2L-CASS4_ASH2L_chr8_37991064_ENST00000545394_CASS4_chr20_55020956_ENST00000434344_length(transcript)=2658nt_BP=1475nt GATGGCGGCGGCAGGAGCAGGACCTGGCCAGGAAGCGGGTGCCGGGCCTGGCCCAGGAGCGGTCGCAAATGCAACAGGGGCAGAAGAGGG GGAGATGAAGCCGGTGGCAGCGGGAGCAGCCGCTCCTCCTGGAGAGGGGATCTCTGCTGCTCCGACAGTTGAGCCCAGTTCCGGGGAGGC TGAAGGCGGGGAGGCAAACTTGGTCGATGTAAGCGGTGGCTTGGAGACAGAATCATCTAATGGAAAAGATACACTAATCCTGTCTACCTT TCATGACCAACTACAGTTTTCATTGCAACGTCTGCCATCACAGTGGGAATACCTATTTCCTCCGGAAGCAAGCAAACTTGAAGGAAATGT GCCTTAGTGCTTTGGCCAACCTGACATGGCAGTCCCGAACACAGGATGAACATCCGAAGACAATGTTCTCCAAAGATAAGGATATTATAC CATTTATTGATAAATACTGGGAGTGCATGACAACCAGACAGAGACCTGGGAAAATGACTTGGCCAAATAACATTGTTAAAACAATGAGTA AAGAAAGAGATGTATTCTTGGTAAAGGAACACCCAGATCCAGGCAGTAAAGATCCAGAAGAAGATTACCCCAAATTTGGACTTTTGGATC AGGACCTTAGTAACATTGGTCCTGCTTATGACAACCAAAAACAGAGCAGTGCTGTGTCTACTAGTGGGAATTTAAATGGGGGAATTGCAG CAGGAAGCAGCGGAAAAGGACGAGGAGCCAAGCGCAAACAGCAGGATGGAGGGACCACAGGGACCACCAAGAAGGCCCGGAGTGACCCTT TGTTTTCTGCTCAGCGCCTTCCCCCTCATGGCTACCCATTGGAACACCCGTTTAACAAAGATGGCTATCGGTATATTCTAGCTGAGCCTG ATCCGCACGCCCCTGACCCCGAGAAGCTGGAACTTGACTGCTGGGCAGGAAAACCTATTCCTGGAGACCTCTACAGAGCCTGCTTGTATG AACGGGTTTTGTTAGCCCTACATGATCGAGCTCCCCAGTTAAAGATCTCAGATGACCGGCTGACTGTGGTTGGAGAGAAGGGCTACTCTA TGGTGAGGGCCTCTCATGGAGTACGGAAAGGTGCCTGGTATTTTGAAATCACTGTGGATGAGATGCCACCAGATACCGCTGCCAGACTGG GTTGGTCCCAGCCCCTAGGAAACCTTCAAGCTCCTTTAGGTTATGATAAATTTAGCTATTCTTGGCGGAGCAAAAAGGGAACCAAGTTCC ACCAGTCCATTGGCAAACACTACTCTTCTGGCTATGGACAGGGAGACGTCCTGGGATTTTATATTAATCTTCCTGAAGACACAGAGACAG CCAAGTCATTGCCAGACACATACAAAGATAAGGCTTTGATAAAATTCAAGAGTTATTTGTATTTTGAGGAAAAAGACTTTGTGGATAAAG CAGAGAAGAGCCTGAAGCAGACTCCCCATAGTGAGGCCATCCTCACGCTTCCCAGACCTGTCCGGGCCTCACTGCCGACTCTGCCTTCCC AGGTGTATGACGTGCCTACCCAGCACCGGGGCCCCGTGGTCCTGAAGGAGCCAGAGAAGCAGCAGTTATATGACATACCAGCCAGCCCCA AGAAGGCAGGACTCCATCCCCCAGACAGCCAAGCAAGTAATCCTGGCCCTCTTATACCTCAGCCTTCGAGTCAACAGACTCCTGAGAGGA AACCCCGCTTATCTGAACACTGCCGGCTCTACTTTGGGGCGCTCTTCAAAGCCATCAGCGCATTTCACGGCAGCCTCAGCAGCAGCCAGC CCGCGGAGATCATCACTCAGAGCAAGCTGGTCATCATGGTGGGACAGAAGCTGGTGGACACGCTGTGCATGGAGACCCAGGAGAGGGACG TGCGCAACGAGATCCTCCGTGGCAGCAGTCACCTCTGCAGCCTGCTCAAGGACGTAGCGCTGGCCACTAAGAATGCCGTGCTCACGTACC CCAGCCCTGCCGCGCTGGGGCACCTCCAGGCGGAGGCTGAGAAGCTGGAGCAACACACGCGGCAGTTCAGAGGGACACTGGGATGAGGAC TGTCTACCTCCCTTCCTCCTCTGCTCACCTCTCAGCTTCACACCCACAACTTGTGCAACTCTGCCCTATGGGAAAAGCCAGCCGGGGCAT ACACCAATGAGCTGAAACAGACCTGGTGCCCAAAGCTGGTAGTACCAAGTGGCTAAGCAACCCCAGGGCATTGACTTACCCCGCAGGGGG TCAGGAAAGAGAGTCAGGTATGAGGTAAAGACCTTGTGAAGTTTAGCATATATGGAGTATGCAGTATCAGCTTGAAGTGACTTCGCAGAA ATAATATTTTATATTGATTAAATGTGTGCATGTTTTGTTTGTTTTTTGAGACAAAGTCTCACTCTGTCACACAGGCTGGAGTGCAGTGGC GCGATCTCAGCTCACTGCAACCTCCGCCTTCTGGGTTGAAGCAATTCTCCCGCCTCAGCCTCCAGAGTAGCTGGTACTACAGGTGTGCGC CACCATGCCCAGCTAATTTTTGTATTTTTTTTTAATGAAAGGTCTCACATATTTATTACTGAACCCAGCCAACCAATGCATTCATAACAG ATTCAGAAAGAAAAAATATATTCCCAATAAAACATGTACAATTCTCCA >7125_7125_15_ASH2L-CASS4_ASH2L_chr8_37991064_ENST00000545394_CASS4_chr20_55020956_ENST00000434344_length(amino acids)=597AA_BP=399 MTNYSFHCNVCHHSGNTYFLRKQANLKEMCLSALANLTWQSRTQDEHPKTMFSKDKDIIPFIDKYWECMTTRQRPGKMTWPNNIVKTMSK ERDVFLVKEHPDPGSKDPEEDYPKFGLLDQDLSNIGPAYDNQKQSSAVSTSGNLNGGIAAGSSGKGRGAKRKQQDGGTTGTTKKARSDPL FSAQRLPPHGYPLEHPFNKDGYRYILAEPDPHAPDPEKLELDCWAGKPIPGDLYRACLYERVLLALHDRAPQLKISDDRLTVVGEKGYSM VRASHGVRKGAWYFEITVDEMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSSGYGQGDVLGFYINLPEDTETA KSLPDTYKDKALIKFKSYLYFEEKDFVDKAEKSLKQTPHSEAILTLPRPVRASLPTLPSQVYDVPTQHRGPVVLKEPEKQQLYDIPASPK KAGLHPPDSQASNPGPLIPQPSSQQTPERKPRLSEHCRLYFGALFKAISAFHGSLSSSQPAEIITQSKLVIMVGQKLVDTLCMETQERDV RNEILRGSSHLCSLLKDVALATKNAVLTYPSPAALGHLQAEAEKLEQHTRQFRGTLG -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for ASH2L-CASS4 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | ASH2L | chr8:37991064 | chr20:55020956 | ENST00000250635 | + | 13 | 15 | 316_628 | 446.0 | 502.0 | RBBP5 |
| Hgene | ASH2L | chr8:37991064 | chr20:55020956 | ENST00000343823 | + | 13 | 16 | 316_628 | 540.0 | 629.0 | RBBP5 |
| Hgene | ASH2L | chr8:37991064 | chr20:55020956 | ENST00000428278 | + | 13 | 16 | 316_628 | 446.0 | 535.0 | RBBP5 |
| Hgene | ASH2L | chr8:37991064 | chr20:55020956 | ENST00000521652 | + | 13 | 15 | 316_628 | 446.0 | 502.0 | RBBP5 |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for ASH2L-CASS4 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for ASH2L-CASS4 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | C0002395 | Alzheimer's Disease | 1 | CTD_human | |
| Tgene | C0011265 | Presenile dementia | 1 | CTD_human | |
| Tgene | C0276496 | Familial Alzheimer Disease (FAD) | 1 | CTD_human | |
| Tgene | C0494463 | Alzheimer Disease, Late Onset | 1 | CTD_human | |
| Tgene | C0546126 | Acute Confusional Senile Dementia | 1 | CTD_human | |
| Tgene | C0750900 | Alzheimer's Disease, Focal Onset | 1 | CTD_human | |
| Tgene | C0750901 | Alzheimer Disease, Early Onset | 1 | CTD_human |
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