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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:ARHGEF2-EIF2C3 (FusionGDB2 ID:HG9181TG192669) |
Fusion Gene Summary for ARHGEF2-EIF2C3 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ARHGEF2-EIF2C3 | Fusion gene ID: hg9181tg192669 | Hgene | Tgene | Gene symbol | ARHGEF2 | EIF2C3 | Gene ID | 9181 | 192669 |
| Gene name | Rho/Rac guanine nucleotide exchange factor 2 | argonaute RISC catalytic component 3 | |
| Synonyms | GEF|GEF-H1|GEFH1|LFP40|Lfc|NEDMHM|P40 | EIF2C3 | |
| Cytomap | ('ARHGEF2','ARHGEF2')('AGO3','EIF2C3') 1q22 | 1p34.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | rho guanine nucleotide exchange factor 2Rho/Rac guanine nucleotide exchange factor (GEF) 2guanine nucleotide exchange factor H1microtubule-regulated Rho-GEFproliferating cell nucleolar antigen p40 | protein argonaute-3argonaute 3, RISC catalytic componenteukaryotic translation initiation factor 2C, 3hAgo3 | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | . | . | |
| Ensembl transtripts involved in fusion gene | ENST00000313667, ENST00000313695, ENST00000361247, ENST00000368315, ENST00000368316, ENST00000462460, ENST00000477754, | ||
| Fusion gene scores | * DoF score | 12 X 15 X 10=1800 | 10 X 6 X 9=540 |
| # samples | 16 | 11 | |
| ** MAII score | log2(16/1800*10)=-3.49185309632968 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(11/540*10)=-2.29545588352617 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ARHGEF2 [Title/Abstract] AND EIF2C3 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | ARHGEF2(155927504)-AGO3(36432556), # samples:1 ARHGEF2(155927504)-EIF2C3(36432556), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | ARHGEF2-AGO3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. ARHGEF2-AGO3 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. ARHGEF2-AGO3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. ARHGEF2-AGO3 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. ARHGEF2-AGO3 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF. ARHGEF2-AGO3 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | ARHGEF2 | GO:0032755 | positive regulation of interleukin-6 production | 21887730 |
| Hgene | ARHGEF2 | GO:0032760 | positive regulation of tumor necrosis factor production | 21887730 |
| Hgene | ARHGEF2 | GO:0045666 | positive regulation of neuron differentiation | 28453519 |
| Hgene | ARHGEF2 | GO:0045944 | positive regulation of transcription by RNA polymerase II | 21887730 |
| Hgene | ARHGEF2 | GO:0050731 | positive regulation of peptidyl-tyrosine phosphorylation | 21887730 |
| Hgene | ARHGEF2 | GO:0051092 | positive regulation of NF-kappaB transcription factor activity | 19043560|21887730 |
| Hgene | ARHGEF2 | GO:0055059 | asymmetric neuroblast division | 28453519 |
| Hgene | ARHGEF2 | GO:0071225 | cellular response to muramyl dipeptide | 21887730 |
| Tgene | EIF2C3 | GO:0006402 | mRNA catabolic process | 18771919 |
| Tgene | EIF2C3 | GO:0010501 | RNA secondary structure unwinding | 19966796 |
| Tgene | EIF2C3 | GO:0031054 | pre-miRNA processing | 19966796 |
| Tgene | EIF2C3 | GO:0035278 | miRNA mediated inhibition of translation | 18771919 |
| Tgene | EIF2C3 | GO:0035279 | mRNA cleavage involved in gene silencing by miRNA | 15260970 |
| Tgene | EIF2C3 | GO:0035280 | miRNA loading onto RISC involved in gene silencing by miRNA | 19966796 |
| Tgene | EIF2C3 | GO:0090625 | mRNA cleavage involved in gene silencing by siRNA | 15260970 |
| Fusion gene breakpoints across ARHGEF2 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across EIF2C3 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | KIRC | TCGA-CW-6097-01A | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + |
| ChimerDB4 | KIRC | TCGA-CW-6097-01A | ARHGEF2 | chr1 | 155927504 | - | EIF2C3 | chr1 | 36432556 | + |
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Fusion Gene ORF analysis for ARHGEF2-EIF2C3 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000313667 | ENST00000246314 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + |
| 5CDS-intron | ENST00000313667 | ENST00000471099 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + |
| 5CDS-intron | ENST00000313695 | ENST00000246314 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + |
| 5CDS-intron | ENST00000313695 | ENST00000471099 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + |
| 5CDS-intron | ENST00000361247 | ENST00000246314 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + |
| 5CDS-intron | ENST00000361247 | ENST00000471099 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + |
| 5CDS-intron | ENST00000368315 | ENST00000246314 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + |
| 5CDS-intron | ENST00000368315 | ENST00000471099 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + |
| 5CDS-intron | ENST00000368316 | ENST00000246314 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + |
| 5CDS-intron | ENST00000368316 | ENST00000471099 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + |
| 5CDS-intron | ENST00000462460 | ENST00000246314 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + |
| 5CDS-intron | ENST00000462460 | ENST00000471099 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + |
| Frame-shift | ENST00000368316 | ENST00000324350 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + |
| Frame-shift | ENST00000368316 | ENST00000373191 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + |
| Frame-shift | ENST00000368316 | ENST00000397828 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + |
| Frame-shift | ENST00000462460 | ENST00000324350 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + |
| Frame-shift | ENST00000462460 | ENST00000373191 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + |
| Frame-shift | ENST00000462460 | ENST00000397828 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + |
| In-frame | ENST00000313667 | ENST00000324350 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + |
| In-frame | ENST00000313667 | ENST00000373191 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + |
| In-frame | ENST00000313667 | ENST00000397828 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + |
| In-frame | ENST00000313695 | ENST00000324350 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + |
| In-frame | ENST00000313695 | ENST00000373191 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + |
| In-frame | ENST00000313695 | ENST00000397828 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + |
| In-frame | ENST00000361247 | ENST00000324350 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + |
| In-frame | ENST00000361247 | ENST00000373191 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + |
| In-frame | ENST00000361247 | ENST00000397828 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + |
| In-frame | ENST00000368315 | ENST00000324350 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + |
| In-frame | ENST00000368315 | ENST00000373191 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + |
| In-frame | ENST00000368315 | ENST00000397828 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + |
| intron-3CDS | ENST00000477754 | ENST00000324350 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + |
| intron-3CDS | ENST00000477754 | ENST00000373191 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + |
| intron-3CDS | ENST00000477754 | ENST00000397828 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + |
| intron-intron | ENST00000477754 | ENST00000246314 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + |
| intron-intron | ENST00000477754 | ENST00000471099 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000368315 | ARHGEF2 | chr1 | 155927504 | - | ENST00000324350 | AGO3 | chr1 | 36432556 | + | 2974 | 1718 | 0 | 2216 | 738 |
| ENST00000368315 | ARHGEF2 | chr1 | 155927504 | - | ENST00000373191 | AGO3 | chr1 | 36432556 | + | 20865 | 1718 | 0 | 4109 | 1369 |
| ENST00000368315 | ARHGEF2 | chr1 | 155927504 | - | ENST00000397828 | AGO3 | chr1 | 36432556 | + | 2586 | 1718 | 0 | 2216 | 738 |
| ENST00000313695 | ARHGEF2 | chr1 | 155927504 | - | ENST00000324350 | AGO3 | chr1 | 36432556 | + | 2999 | 1743 | 112 | 2241 | 709 |
| ENST00000313695 | ARHGEF2 | chr1 | 155927504 | - | ENST00000373191 | AGO3 | chr1 | 36432556 | + | 20890 | 1743 | 112 | 4134 | 1340 |
| ENST00000313695 | ARHGEF2 | chr1 | 155927504 | - | ENST00000397828 | AGO3 | chr1 | 36432556 | + | 2611 | 1743 | 112 | 2241 | 709 |
| ENST00000361247 | ARHGEF2 | chr1 | 155927504 | - | ENST00000324350 | AGO3 | chr1 | 36432556 | + | 3071 | 1815 | 100 | 2313 | 737 |
| ENST00000361247 | ARHGEF2 | chr1 | 155927504 | - | ENST00000373191 | AGO3 | chr1 | 36432556 | + | 20962 | 1815 | 100 | 4206 | 1368 |
| ENST00000361247 | ARHGEF2 | chr1 | 155927504 | - | ENST00000397828 | AGO3 | chr1 | 36432556 | + | 2683 | 1815 | 100 | 2313 | 737 |
| ENST00000313667 | ARHGEF2 | chr1 | 155927504 | - | ENST00000324350 | AGO3 | chr1 | 36432556 | + | 2968 | 1712 | 0 | 2210 | 736 |
| ENST00000313667 | ARHGEF2 | chr1 | 155927504 | - | ENST00000373191 | AGO3 | chr1 | 36432556 | + | 20859 | 1712 | 0 | 4103 | 1367 |
| ENST00000313667 | ARHGEF2 | chr1 | 155927504 | - | ENST00000397828 | AGO3 | chr1 | 36432556 | + | 2580 | 1712 | 0 | 2210 | 736 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000368315 | ENST00000324350 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + | 0.006647962 | 0.99335206 |
| ENST00000368315 | ENST00000373191 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + | 8.26E-05 | 0.9999174 |
| ENST00000368315 | ENST00000397828 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + | 0.006545044 | 0.9934549 |
| ENST00000313695 | ENST00000324350 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + | 0.004006254 | 0.99599373 |
| ENST00000313695 | ENST00000373191 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + | 8.97E-05 | 0.99991024 |
| ENST00000313695 | ENST00000397828 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + | 0.004310294 | 0.9956897 |
| ENST00000361247 | ENST00000324350 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + | 0.006735757 | 0.9932642 |
| ENST00000361247 | ENST00000373191 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + | 9.01E-05 | 0.9999099 |
| ENST00000361247 | ENST00000397828 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + | 0.007218152 | 0.9927819 |
| ENST00000313667 | ENST00000324350 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + | 0.006548363 | 0.9934516 |
| ENST00000313667 | ENST00000373191 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + | 8.00E-05 | 0.99992 |
| ENST00000313667 | ENST00000397828 | ARHGEF2 | chr1 | 155927504 | - | AGO3 | chr1 | 36432556 | + | 0.006951049 | 0.9930489 |
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Fusion Genomic Features for ARHGEF2-EIF2C3 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| ARHGEF2 | chr1 | 155927503 | - | AGO3 | chr1 | 36432555 | + | 5.94E-07 | 0.9999994 |
| ARHGEF2 | chr1 | 155927503 | - | AGO3 | chr1 | 36432555 | + | 5.94E-07 | 0.9999994 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for ARHGEF2-EIF2C3 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/:155927504/:36432556) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | . |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | ARHGEF2 | chr1:155927504 | chr1:36432556 | ENST00000313667 | - | 13 | 22 | 235_432 | 570 | 986.0 | Domain | DH |
| Hgene | ARHGEF2 | chr1:155927504 | chr1:36432556 | ENST00000313667 | - | 13 | 22 | 472_571 | 570 | 986.0 | Domain | PH |
| Hgene | ARHGEF2 | chr1:155927504 | chr1:36432556 | ENST00000313695 | - | 13 | 22 | 235_432 | 543 | 959.0 | Domain | DH |
| Hgene | ARHGEF2 | chr1:155927504 | chr1:36432556 | ENST00000361247 | - | 13 | 22 | 235_432 | 571 | 987.0 | Domain | DH |
| Hgene | ARHGEF2 | chr1:155927504 | chr1:36432556 | ENST00000361247 | - | 13 | 22 | 472_571 | 571 | 987.0 | Domain | PH |
| Hgene | ARHGEF2 | chr1:155927504 | chr1:36432556 | ENST00000368316 | - | 17 | 26 | 235_432 | 543 | 959.0 | Domain | DH |
| Hgene | ARHGEF2 | chr1:155927504 | chr1:36432556 | ENST00000313667 | - | 13 | 22 | 39_86 | 570 | 986.0 | Zinc finger | Phorbol-ester/DAG-type |
| Hgene | ARHGEF2 | chr1:155927504 | chr1:36432556 | ENST00000313695 | - | 13 | 22 | 39_86 | 543 | 959.0 | Zinc finger | Phorbol-ester/DAG-type |
| Hgene | ARHGEF2 | chr1:155927504 | chr1:36432556 | ENST00000361247 | - | 13 | 22 | 39_86 | 571 | 987.0 | Zinc finger | Phorbol-ester/DAG-type |
| Hgene | ARHGEF2 | chr1:155927504 | chr1:36432556 | ENST00000368316 | - | 17 | 26 | 39_86 | 543 | 959.0 | Zinc finger | Phorbol-ester/DAG-type |
| Tgene | AGO3 | chr1:155927504 | chr1:36432556 | ENST00000246314 | 0 | 17 | 236_349 | 0 | 627.0 | Domain | PAZ | |
| Tgene | AGO3 | chr1:155927504 | chr1:36432556 | ENST00000246314 | 0 | 17 | 518_819 | 0 | 627.0 | Domain | Piwi | |
| Tgene | AGO3 | chr1:155927504 | chr1:36432556 | ENST00000373191 | 1 | 19 | 236_349 | 63 | 861.0 | Domain | PAZ | |
| Tgene | AGO3 | chr1:155927504 | chr1:36432556 | ENST00000373191 | 1 | 19 | 518_819 | 63 | 861.0 | Domain | Piwi |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | ARHGEF2 | chr1:155927504 | chr1:36432556 | ENST00000313667 | - | 13 | 22 | 587_611 | 570 | 986.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | ARHGEF2 | chr1:155927504 | chr1:36432556 | ENST00000313667 | - | 13 | 22 | 798_867 | 570 | 986.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | ARHGEF2 | chr1:155927504 | chr1:36432556 | ENST00000313695 | - | 13 | 22 | 587_611 | 543 | 959.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | ARHGEF2 | chr1:155927504 | chr1:36432556 | ENST00000313695 | - | 13 | 22 | 798_867 | 543 | 959.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | ARHGEF2 | chr1:155927504 | chr1:36432556 | ENST00000361247 | - | 13 | 22 | 587_611 | 571 | 987.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | ARHGEF2 | chr1:155927504 | chr1:36432556 | ENST00000361247 | - | 13 | 22 | 798_867 | 571 | 987.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | ARHGEF2 | chr1:155927504 | chr1:36432556 | ENST00000368316 | - | 17 | 26 | 587_611 | 543 | 959.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | ARHGEF2 | chr1:155927504 | chr1:36432556 | ENST00000368316 | - | 17 | 26 | 798_867 | 543 | 959.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | ARHGEF2 | chr1:155927504 | chr1:36432556 | ENST00000313695 | - | 13 | 22 | 472_571 | 543 | 959.0 | Domain | PH |
| Hgene | ARHGEF2 | chr1:155927504 | chr1:36432556 | ENST00000368316 | - | 17 | 26 | 472_571 | 543 | 959.0 | Domain | PH |
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Fusion Gene Sequence for ARHGEF2-EIF2C3 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >6279_6279_1_ARHGEF2-AGO3_ARHGEF2_chr1_155927504_ENST00000313667_AGO3_chr1_36432556_ENST00000324350_length(transcript)=2968nt_BP=1712nt ATGTCTCGGATCGAATCCCTCACGCGGGCGCGGATCGACCGGAGCAGAGAGCTGGCGAGCAAGACCCGGGAAAAGGAGAAGATGAAGGAA GCCAAGGATGCCCGCTATACCAATGGGCACCTCTTCACCACCATTTCAGTTTCAGGCATGACCATGTGCTATGCCTGTAACAAGAGCATC ACAGCCAAGGAAGCCCTCATCTGCCCAACCTGCAATGTGACTATCCACAACCGCTGTAAAGACACCCTCGCCAACTGTACCAAGGTCAAG CAGAAGCAACAGAAAGCGGCCCTGCTGAAGAACAACACCGCCTTGCAGTCCGTTTCTCTTCGAAGTAAGACAACCATCCGGGAGCGGCCA AGCTCGGCCATCTACCCCTCCGACAGCTTCCGGCAGTCCCTCCTGGGCTCCCGCCGTGGCCGCTCCTCCTTGTCTTTAGCCAAGAGTGTT TCTACCACCAACATTGCTGGACATTTCAATGATGAGTCTCCCCTGGGGCTGCGCCGGATCCTCTCACAGTCCACAGACTCCCTCAACATG CGGAACCGAACCCTATCCGTGGAATCCCTCATTGACGAAGAGGTAATCTACAGTGAGCTGATGAGTGACTTTGAGATGGATGAGAAGGAC TTTGCAGCTGACTCTTGGAGTCTTGCTGTGGACAGCAGCTTCCTGCAGCAGCATAAAAAGGAGGTGATGAAGCAGCAAGATGTCATCTAT GAGCTAATCCAGACAGAGCTGCACCATGTGAGGACACTGAAGATCATGACCCGCCTCTTCCGCACGGGGATGCTGGAAGAGCTACACTTG GAGCCAGGAGTGGTCCAGGGCCTGTTCCCCTGCGTGGACGAGCTCAGTGACATCCATACACGCTTCCTCAGCCAGCTATTAGAACGCCGA CGCCAGGCCCTGTGCCCTGGCAGCACCCGGAACTTTGTCATCCATCGCTTGGGTGATCTGCTCATCAGCCAGTTCTCAGGTCCTAGTGCG GAGCAGATGTGTAAGACCTACTCGGAGTTCTGCAGCCGCCACAGCAAGGCCTTAAAGCTCTATAAGGAGCTGTACGCCCGAGACAAACGC TTCCAGCAATTCATCCGGAAAGTGACCCGCCCCGCCGTGCTCAAGCGGCACGGGGTACAGGAGTGCATCCTGCTGGTGACTCAGCGCATC ACCAAGTACCCGTTACTCATCAGCCGCATCCTGCAGCATTCCCACGGGATCGAGGAGGAGCGCCAGGACCTGACCACAGCACTGGGGCTA GTGAAGGAGCTGCTGTCCAATGTGGACGAGGGTATTTATCAGCTGGAGAAAGGGGCCCGTCTGCAGGAGATCTACAACCGCATGGACCCT CGGGCCCAAACCCCAGTGCCTGGCAAGGGCCCCTTTGGCCGAGAGGAACTTCTGAGGCGCAAACTCATCCACGATGGCTGCCTGCTCTGG AAGACAGCGACGGGGCGCTTCAAAGATGTGCTAGTGCTGCTGATGACAGATGTACTGGTGTTTCTCCAGGAAAAGGACCAGAAGTACATC TTTCCTACCCTGGACAAGCCTTCAGTGGTATCGCTGCAGAATCTAATCGTACGAGACATTGCCAACCAGGAGAAAGGGATGTTTCTGATC AGCGCAGCCCCACCTGAGATGTACGAGGTGCACACAGCATCCCGGGATGACCGGAGCACCTGGATCCGGGTCATTCAGCAGAGCGTGCGC ACGGAGGTGGTTGACTCAATGGTTCAGCATTTTAAAGTAACTATATTTGGAGACCGTAGACCAGTTTATGATGGAAAAAGAAGTCTTTAC ACCGCCAATCCACTTCCTGTGGCAACTACAGGGGTAGATTTAGACGTTACTTTACCTGGGGAAGGTGGAAAAGATCGACCTTTCAAGGTG TCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACGGACCTTGCCTGAGCCACTGGAATTAGACAAG CCAATCAGCACTAACCCTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCATGAAATACACACCTGTGGGGCGTTCATTTTTC TCCGCTCCAGAAGGATATGACCACCCTCTGGGAGGGGGCAGGGAAGTGTGGTTTGGATTCCATCAGTCTGTTCGGCCTGCCATGTGGAAA ATGATGCTTAATATCGATGAAAGAGACCTCTGGCAGCAGTGTGGAGAATAGATAGAGGAGAAAAAACTAATCTGAGAAGCCAGTTAGGAG GCTTTTCAATCACTAGTTCAGGTAAGAGATGGTGATGGTCTAATGTGGGATGGAGAGGAAGGATTAAGCTGAAAAAATAGGTTTAAGAAC CATGTCCAGAAAAAAAAAACTTTGGGTGTAGTACTGGTACATGGAACGGATTGGAAAAAAATAGACCAGAGCTTTACTAGATTTTTGAAA GAATTGTTTTTGCAAATAAACTACAAGCCTGGCATATCAGTCAAGGTTCAGAACCTAGAGAAGCAGAACCAGTACGAAGTATAGAGAGAG AGTTTATGCAATTGTAGGGGCTAGCTAGGCAAGTCTGAAATTTTGGGGGCAGGCTGTCAGGAAGGGCAGGGAAATTCAGGCATGGGCTGA AGCAGTTATCTATAAGTGGAATTTCTTGCTCTCAGGGAAGCTTCAGCCCTACTTTTAAGACCTTTCACCTAATTGAATCAGGCCCATCCA CATTATTCAGGATAATCTCCATTACTTAAAGTCAACAGATTATGGATTTTAATTACATCTACAAAATACCTTCATAGCAACACCTAGATT AGTGTTTGATTAAACAAATGGCAGCTGGTAGCCTAGCAAGTTAACACATTAAAAACAACACCTGCCATGATGGCTTACACTTGTAATCCC >6279_6279_1_ARHGEF2-AGO3_ARHGEF2_chr1_155927504_ENST00000313667_AGO3_chr1_36432556_ENST00000324350_length(amino acids)=736AA_BP=571 MSRIESLTRARIDRSRELASKTREKEKMKEAKDARYTNGHLFTTISVSGMTMCYACNKSITAKEALICPTCNVTIHNRCKDTLANCTKVK QKQQKAALLKNNTALQSVSLRSKTTIRERPSSAIYPSDSFRQSLLGSRRGRSSLSLAKSVSTTNIAGHFNDESPLGLRRILSQSTDSLNM RNRTLSVESLIDEEVIYSELMSDFEMDEKDFAADSWSLAVDSSFLQQHKKEVMKQQDVIYELIQTELHHVRTLKIMTRLFRTGMLEELHL EPGVVQGLFPCVDELSDIHTRFLSQLLERRRQALCPGSTRNFVIHRLGDLLISQFSGPSAEQMCKTYSEFCSRHSKALKLYKELYARDKR FQQFIRKVTRPAVLKRHGVQECILLVTQRITKYPLLISRILQHSHGIEEERQDLTTALGLVKELLSNVDEGIYQLEKGARLQEIYNRMDP RAQTPVPGKGPFGREELLRRKLIHDGCLLWKTATGRFKDVLVLLMTDVLVFLQEKDQKYIFPTLDKPSVVSLQNLIVRDIANQEKGMFLI SAAPPEMYEVHTASRDDRSTWIRVIQQSVRTEVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFKV SIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWK -------------------------------------------------------------- >6279_6279_2_ARHGEF2-AGO3_ARHGEF2_chr1_155927504_ENST00000313667_AGO3_chr1_36432556_ENST00000373191_length(transcript)=20859nt_BP=1712nt ATGTCTCGGATCGAATCCCTCACGCGGGCGCGGATCGACCGGAGCAGAGAGCTGGCGAGCAAGACCCGGGAAAAGGAGAAGATGAAGGAA GCCAAGGATGCCCGCTATACCAATGGGCACCTCTTCACCACCATTTCAGTTTCAGGCATGACCATGTGCTATGCCTGTAACAAGAGCATC ACAGCCAAGGAAGCCCTCATCTGCCCAACCTGCAATGTGACTATCCACAACCGCTGTAAAGACACCCTCGCCAACTGTACCAAGGTCAAG CAGAAGCAACAGAAAGCGGCCCTGCTGAAGAACAACACCGCCTTGCAGTCCGTTTCTCTTCGAAGTAAGACAACCATCCGGGAGCGGCCA AGCTCGGCCATCTACCCCTCCGACAGCTTCCGGCAGTCCCTCCTGGGCTCCCGCCGTGGCCGCTCCTCCTTGTCTTTAGCCAAGAGTGTT TCTACCACCAACATTGCTGGACATTTCAATGATGAGTCTCCCCTGGGGCTGCGCCGGATCCTCTCACAGTCCACAGACTCCCTCAACATG CGGAACCGAACCCTATCCGTGGAATCCCTCATTGACGAAGAGGTAATCTACAGTGAGCTGATGAGTGACTTTGAGATGGATGAGAAGGAC TTTGCAGCTGACTCTTGGAGTCTTGCTGTGGACAGCAGCTTCCTGCAGCAGCATAAAAAGGAGGTGATGAAGCAGCAAGATGTCATCTAT GAGCTAATCCAGACAGAGCTGCACCATGTGAGGACACTGAAGATCATGACCCGCCTCTTCCGCACGGGGATGCTGGAAGAGCTACACTTG GAGCCAGGAGTGGTCCAGGGCCTGTTCCCCTGCGTGGACGAGCTCAGTGACATCCATACACGCTTCCTCAGCCAGCTATTAGAACGCCGA CGCCAGGCCCTGTGCCCTGGCAGCACCCGGAACTTTGTCATCCATCGCTTGGGTGATCTGCTCATCAGCCAGTTCTCAGGTCCTAGTGCG GAGCAGATGTGTAAGACCTACTCGGAGTTCTGCAGCCGCCACAGCAAGGCCTTAAAGCTCTATAAGGAGCTGTACGCCCGAGACAAACGC TTCCAGCAATTCATCCGGAAAGTGACCCGCCCCGCCGTGCTCAAGCGGCACGGGGTACAGGAGTGCATCCTGCTGGTGACTCAGCGCATC ACCAAGTACCCGTTACTCATCAGCCGCATCCTGCAGCATTCCCACGGGATCGAGGAGGAGCGCCAGGACCTGACCACAGCACTGGGGCTA GTGAAGGAGCTGCTGTCCAATGTGGACGAGGGTATTTATCAGCTGGAGAAAGGGGCCCGTCTGCAGGAGATCTACAACCGCATGGACCCT CGGGCCCAAACCCCAGTGCCTGGCAAGGGCCCCTTTGGCCGAGAGGAACTTCTGAGGCGCAAACTCATCCACGATGGCTGCCTGCTCTGG AAGACAGCGACGGGGCGCTTCAAAGATGTGCTAGTGCTGCTGATGACAGATGTACTGGTGTTTCTCCAGGAAAAGGACCAGAAGTACATC TTTCCTACCCTGGACAAGCCTTCAGTGGTATCGCTGCAGAATCTAATCGTACGAGACATTGCCAACCAGGAGAAAGGGATGTTTCTGATC AGCGCAGCCCCACCTGAGATGTACGAGGTGCACACAGCATCCCGGGATGACCGGAGCACCTGGATCCGGGTCATTCAGCAGAGCGTGCGC ACGGAGGTGGTTGACTCAATGGTTCAGCATTTTAAAGTAACTATATTTGGAGACCGTAGACCAGTTTATGATGGAAAAAGAAGTCTTTAC ACCGCCAATCCACTTCCTGTGGCAACTACAGGGGTAGATTTAGACGTTACTTTACCTGGGGAAGGTGGAAAAGATCGACCTTTCAAGGTG TCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACGGACCTTGCCTGAGCCACTGGAATTAGACAAG CCAATCAGCACTAACCCTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCATGAAATACACACCTGTGGGGCGTTCATTTTTC TCCGCTCCAGAAGGATATGACCACCCTCTGGGAGGGGGCAGGGAAGTGTGGTTTGGATTCCATCAGTCTGTTCGGCCTGCCATGTGGAAA ATGATGCTTAATATCGATGTTTCTGCCACTGCCTTCTACAAAGCACAACCTGTAATTCAGTTCATGTGTGAAGTTCTTGATATTCATAAT ATTGATGAGCAACCAAGACCTCTGACTGATTCTCATCGGGTAAAATTCACCAAAGAGATAAAAGGTTTGAAGGTTGAAGTGACTCATTGT GGAACAATGAGACGGAAATACCGTGTTTGTAATGTAACAAGGAGGCCTGCCAGTCATCAAACCTTTCCTTTACAGTTAGAAAACGGCCAA ACTGTGGAGAGAACAGTAGCGCAGTATTTCAGAGAAAAGTATACTCTTCAGCTGAAGTACCCGCACCTTCCCTGTCTGCAAGTCGGGCAG GAACAGAAACACACCTACCTGCCACTAGAAGTCTGTAATATTGTGGCAGGGCAACGATGTATCAAGAAGCTAACAGACAATCAGACTTCC ACTATGATCAAGGCAACAGCAAGATCTGCACCAGATAGACAAGAGGAAATTAGCAGATTGGTAAGAAGTGCAAATTATGAAACAGATCCA TTTGTTCAGGAGTTTCAATTTAAAGTTCGGGATGAAATGGCTCATGTAACTGGACGCGTACTTCCAGCACCTATGCTCCAGTATGGAGGA CGGAATCGGACAGTAGCAACACCGAGCCATGGAGTATGGGACATGCGAGGGAAACAATTCCACACAGGAGTTGAAATCAAAATGTGGGCT ATCGCTTGTTTTGCCACACAGAGGCAGTGCAGAGAAGAAATATTGAAGGGTTTCACAGACCAGCTGCGTAAGATTTCTAAGGATGCAGGG ATGCCCATCCAGGGCCAGCCATGCTTCTGCAAATATGCACAGGGGGCAGACAGCGTAGAGCCCATGTTCCGGCATCTCAAGAACACATAT TCTGGCCTACAGCTTATTATCGTCATCCTGCCGGGGAAGACACCAGTGTATGCGGAAGTGAAACGTGTAGGAGACACACTTTTGGGTATG GCTACACAATGTGTTCAAGTCAAGAATGTAATAAAAACATCTCCTCAAACTCTGTCAAACTTGTGCCTAAAGATAAATGTTAAACTCGGA GGGATCAATAATATTCTTGTACCTCATCAAAGACCTTCTGTGTTCCAGCAACCAGTGATCTTTTTGGGAGCCGATGTCACTCATCCACCT GCTGGTGATGGAAAGAAGCCTTCTATTGCTGCTGTTGTAGGTAGTATGGATGCACACCCAAGCAGATACTGTGCCACAGTAAGAGTTCAG AGACCCCGACAGGAGATCATCCAGGACTTGGCCTCCATGGTCCGGGAACTTCTTATTCAATTTTATAAGTCAACTCGGTTCAAGCCTACT CGTATCATCTTTTATCGGGATGGTGTTTCAGAGGGGCAGTTTAGGCAGGTATTATATTATGAACTACTAGCAATTCGAGAAGCCTGCATC AGTTTGGAGAAAGACTATCAACCTGGAATAACCTACATTGTAGTTCAGAAGAGACATCACACTCGATTATTTTGTGCTGATAGGACAGAA AGGGTTGGAAGAAGTGGCAATATCCCAGCTGGAACAACAGTTGATACAGACATTACACACCCATATGAGTTCGATTTTTACCTCTGTAGC CATGCTGGAATACAGGGTACCAGTCGTCCTTCACACTATCATGTTTTATGGGATGATAACTGCTTTACTGCAGATGAACTTCAGCTGCTA ACTTACCAGCTCTGCCACACTTACGTACGCTGTACACGATCTGTTTCTATACCTGCACCAGCGTATTATGCTCACCTGGTAGCATTTAGA GCCAGATATCATCTTGTGGACAAAGAACATGACAGTGCTGAAGGAAGTCACGTTTCAGGACAAAGCAATGGGCGAGATCCACAAGCTCTT GCCAAGGCTGTACAGATTCACCAAGATACCTTACGCACAATGTACTTCGCTTAAATAGTCCAAGTATATTCTCTGAGAGGAAGTACTGAA AGATGAATTGACATACAACGTATGTTTCCAGTGAAGTCAATTGAGTAAGGACACCTCCAGCCATACAGAAACCAACACTGTGTGGGGGCC AAGGTCTGATCCTTATGTTAATACAAGGAAGATTGTTTACTTCATCAAGGAACACAGCATCATTATGCAATATGAAACCAGCCAACTGCT TTTTGTGCGGTCTCCTATAGGAAGTATCGCAATTGTTTTGTTTTCATTTCTTGTAGTCTAACCCTTTTAATGCCTTTACCTCAAGTTGCT TGGCAGCACAACTATCTTTGCAAAAAAAAGTAAAGAAAAAGTAAATGATGGTTTAAAAAATACACACCTTCATGAATAATCAAAGTGATT TTTCAGAATTATGTGTGCAAAAAATTAATGTGCATTCATATATTCTTGTAAAAGGTGTCTGTGTATTTTTAAAATATATACATCCATACT TCATATGCATATATATCTAGATCTGGATTGATAATAGATATATATGTGTCTGTTATATATTTTAGAGTTCATTCCATTGGGGAATTTTCT TTCCCTTTTATTCTACCCCCACTACCGCCTTTATTTCTCTATTTCCCTTGCCTTCATCACCTACATTTTTTTCCCAGTCCTACCAGTGAC ATTCAAATGTTGATGTATCTGGTTCGTTTGAATATAAAATATGGCAAACTAGAATTCTACTTTTATTTTGCATACCCTACTCCTGACTCC TATCTCATACACAATTCTGAGTTCTCAACTCTTGATATTGCTGTCTTAAGAAACAAAATTTTATATATATATGTATACATACATACACAG ACACAGACACACACATATATATACATAAAATAACTTTCTGTGAGAGTGCGTCTCTCCCCTCCCACTCAGAACATACATTTACCATTTGCG CAATTTGTATATAAGCAGTAGCAACCTGAACTATTCTTTTTCTTTTTTCTTTTTCTTTTCTTTCTTTTTTTTTTTTAATGAGACAGAGCC TCGCTCTGTCACCAGGCTGGAGTGCAGTGGCGAGATCTCGGCTCACTGCAACTTCCGCCTCTCGGGTTCAAGCAATTCTCCTGCCTCAGC CTCCCGAGTAGCTGGGTTTACAGGCATGTGCCACCACACCCAGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCGTGTTGGCCA GGATGGTCTCGATCTCTTGACCTTGTGATCCACCCGCCTCGACCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCACCCGGCCTA CTATTCTTTTTCTTTAGTGAGTTTGTTAAAGCTGCTATAAATATAAAACCTGTCAGAAGTTGTAACTTTCTCTCTGGTAAGTGATGTGTA TTCTGAAGCCTTCTGTTTCTATGGGTTATACATGGAAATTCTTTAAAGGTTTTATAAAGGGTAAATATTTTAAAAGATTAGAGCTCTGTA GGGTTGAGACCTCTGAAATTGAGTAGAGAGAAGAGTTTGTTGAGGGATTTTTTTGTTTTGTTTTTTGATAGTTTACTTGCTGCCTCTCAT ACCTTAATGTGATTTTCATATATTTTTTATATATATATATGTATGTGTGTGTATATAAACACATATGTATGTGTTTGGAAGTATAGCTTC CTTTTCTTTTATATTTATTAGAATAGTGCTTTAATAATTATAGAATTGTATTGGCAGCATCTTTTATAGAAATATAATCATGTTTATTTT AAGAACTGACAACTTGTTTTTGCTATCTTTTAGTGCAATAAGCAGTTTTAAAGGAAAGTTGTGTCTGCATCTTTACCATGGATAGTAGGA GGAACAGGCACCTCCATAGTTTAAAAGGGCAAAGAATACAGCCTTAATTTCAGAAGGAAAGTTTTGTAATTTTCAGTTTTAAAGCATATC TTTTAAAATTCATCATGATAAAAGGCTGGACGCGGTGGCTCATGCCTGTAATCCTAGCACTTTGGGAGGCTGAGACAGGTATATCACCGG AGCTCAGGAGTTTGAGACCAGCCTGGCCAACGTGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCTGGGCGTGGTAGTGGGCAC CTCTAATCCCAGCTACTCGGGAGGCTGAGGCAGGATTGCTTGAACCTAGGAGGCGGAAGTTACAGTGAGCCAAGACTGCACCATTGCACT CCAGCCTGGGCAACAAAACCAAAACTCCGTCTCAAAAGAAAAAAAAATCATAATGAAAATGAAGTGAAATTGCCTAAATGAGTCCAACTT GAATATTAGAAATAAAGTTGAACTTTTATATAATTGTGAATAGCTTAACATATTTAAATTATTTGCAAATAGATTGTGTTTATTGAAGAA TCATATTGGCTAGATGCCCATTTTCATTTACTAAAATGAATCAGGAAAATGCAAGATGATATTTTAAAACTTTTGCTAATGTATCACCAG TATAACTTTCCTTTTAAAATTAAGGTGATAGTAACAAAGGAAGTTAGGACTTTGATCATTTTAAATCAGTTAAATCACTGAAACGTGGGA AATTGTTTTACAAAACTTTTATTGATTACACTTTAAGGTATTAAAAAGTACTATAAAGCTATCAAAACTGAGTTTATCAGTAACATTGGA TTCAGGGGAGCTTTGCACTTTGTAACTCATGAAAATTGCATTTTGATTTTTTTTTTTTTTGCACTGGTTCAGAGTATAGATACTACAGAT TGTTTCCAGTGGGCATTGTTGTTAGCCTTTCAGAATTCCATCTGCACGTGAAACCTAATGGATTTAGATCTTTAGTTTCTCTCTTACCTG TAATCCACTATTATTGCCAATTCACTGTATTTTGAGCCTAAAATCTGAGCCCATGTCCTCTGACAGGCATGAAATCTTTTGTCCCTCTGC CAGAAAACTAAGAAAGTACTGTATTTTGTATGTTTATTATTTTGAAGTGTCTGAAATGCAATTTACAACACTGTTGCAAAGAACTTTACA AAAGGTAATATTTGTATCGTATATACATTTTTTCTCCCAGCCTTCTCCCATCTCCTCCAGAAAAATTTCCTATAAAGATGGATTTTTTTA CACTGAAATTTTACTGAATATAGTCAGGATCATGGGCAAGAGAAGAAAATAGTATACCCAAGATGATAAAAATTTAATTCGTCTATGCTT GATCAGTGTGAGTAAAACATCTTCCTTTATCATGGGAGCTGCACAGATTCATGTGGGAAACTTTAGGGAATGACTGTAGATACCCTTTCT CTATGTACTCTCTCACCTAATTTTCAGTCACTCATATATGCTAGAGTGGAGCCCTTAATTTAAATCTATTTGGAAGGACTTTTTTAAGAG GAAAAATATTTTTTCTAAATTATAAAGCTTTACCTTTTGAGTGATTTCTTTTTTAGAGTGCTCTTACACTAGTCAGCATTGCTAGTTTAA AGTTGATTAACTTGAAAGAGTATGTATACTATATTTCTATTTTGCTAACAAATTGGTATATTAATTACCATTGGTTCTTAATTACAAGAA AACTTGTGCTTAGAATTTTAAGATAAAAGGCTAAGTGACAAATGCTTCTTGAAATTTGTCCTATTTATTGTTGCATTTCTGGTGTAGAAT TTCTAATCTTTTTTATTTTAAAAAAGTTTTTTTTTTTAAGTTAAACATGAAATTCACAGTGACCCTTCTGCTCCTGCCCTTGCTCACTAA CTATATCATGAATGCTAGATTTTGGTCTTCTTTTTTCTGTGATGTATCTTACGAGACTGACTGTAAAATATCAGTCTGGCAACTAGATAA TTGATTTTCATATGAAGAAGAGTTGGGAGTTTAATGTATATTCTTGATGGTTAATGTGTCTACATAAAGTGCTGATACATGTATTATATC ACAGTATCAGGTTACTGGCATGGAGGACCATACACTTACAATATTGTAGCTGCTATATTTATTTAAGTAGATTCTGACAGTTACTGCACT AAACAGTAAGGAGATAAGCAGGATTCAAGGCTAGTGTTAGACCCTTTTTTTTCCTAAGAGTAAGGACACGGAATATCAAAGTAACAAAGG GTGCTGCCATTTTAGTTTCAATTTAATATCAGGATATTCTTTGTTTTAGAAATGTAGATTTTGACTTTTACAGTTTGAAAAAGGGTACCT CAGCCTCTTCAGTACTGGTTTTTTGGCACATTTCAACAGAAATATTAGATTCCCTTTCTTTTTCTTAATAGTGATCTTCTAACAAGTTTC TTGGAAAAACTATCATTCTAAGGGAAATCCCTGTTTATAACCTATTAATATATTTCTATTCCTAGAAGAGAGTCTAGCAGGGATTCTAGT AGGAATTACTGAGTGTTTTGGAAGGCACTTGATAGAGGCATCTCTGCTTTCCAGCACAGGGATTCTCAGCCTTCTAAAGATCTAGACCAG TTTCCAAGCTAGCTTCTCCACAGCCCACCACTGCCTAGTGTTTGCTTGTGTATTCTCTAATGGATTTTAGGAGGATAGGCCTTCTGACAG AGTCATGAAAGACTGAAGGCATGTCTAGGGAAATAAAACCTGACTTGCCCTTCAGCAGGAATGACTGGCAGCGGATCTCTGTGTTCAAGG AAAGGGTGAGCGCTAAGCATGCCAGTGATGGATCCGAAGTATTTAGATGGATTGCAGACCAGGAATTAGAGACCGTTTGTGACTCAAGGA ACTTGATGGATCTGTTTAGAGCCCTACATGAATTTGCCAAGGGCAGTGATTTTTATGAAATTCAAGAAGCAAACGACTTCGATACAGCTA GAATATGTTGCAGTCTTCCTATTTCAAACTTGATTTTAATATTTTTACCAAGAAGTTTAACTGACAACTCTGCAAAATTTTCATTCAGTA TCATTAAACCTGAGTTAAATGTTTGCTTAGCTTATCCTCTTAGATGTTCTTCTGTTGAACAGGCAGGTTGCCCTTAACAGTAACTTGCTA CTTAAATTACCTTTTATTAGTTAGTCAAGCTGCAAAAATATCATTAGTGTGGCGTCTTTATTTTGGCTTTATCCATATGAAGTATTCATT ATTTTCATTCTTTTTGAGAATTCATAAATGTCTTAAAGCTTCAGTAAGAATTGTTGGGAGGTTTGACATCAAGTAACGCCTTCCTGTGTA GCAGTATAACCCTAATTTAGAACTCTTGTTTTCCTATTTCAGTCCTCATATTTGATCATAGAAAAGCACTTTTGTGATTCTATAGGAGTC AAAAAATCAGCCAAGAGTAGGTAAGTCAGTCAGCACAGAAATCAGAAAGTGAGAATTTTCTCCAAAAAATCTTTTTAAAAAAGTCCTGCT TATACTAAGAACATTCTTGATCCGTTGCAGTGTTAGAAATGACACTGTGATTAGTGAAAGCCAAGCTGAGTCCCAGGAAGCAGGGAGGGG GAGTGTGTGTGTGTGTATATGTATGAGTGTGTATATATATAATCTCACACACACACACAAAGGGAAAAATTATTTTGACTTTTTTCCTAC TTTTAAAATGGTACATTTAAGTTTATAATTTTCCATGTCAGTCAACATAATTTTTTAAACTAAGGTATAATGGTCAAGGCTTGTGCTAAT ATTACCTACTACTCATTGAAATTTATATTACTTTACCCATCAAAACTAGTACTCCAGATGTTTACATCATTGATTAAATCTCAAGAATCT TTTGTTCTTAAAATATGGAAGTTAAAGATTTTAATTTGAATTAAAGATAGAAGGATGGTAAATTCAATATAGAGGGTTGAGATTTACCAG TGAGAAACCCTGTTGAAGTATCAGGTAAATGGTGTGACAAAATTAGAATCCTGTCAAATCACCTATCCAGCCATCGGGGTCCCTTCCTTT TTTAGACTAATTTCTAAGGTAACCAGAATCTAATGTATCTATGTTAGGGTCTCAGTAAAGCAAAGACGTTTGTCAGGGCGTAGACTCTTG AGTTAAATTTTTTAATCATTTTTTAAAGCAAGGCGGTTCTTAGAAAGTGCCTTTTCAGAAGATGGTGCTGTAGATTTTTATTTTTCAAGT AGCACGAAGCTAAGAATTTTAAAGATAAATTATTTTAGAACTCCAAGAGTGTGACAGTTTCATAAAAATAATGTTAGTTGTTGTCTTGAA TCTCGTCCAAGGGAACCAAGGAAAGCTTTTATGCAGTAAAGTATCTAGGTAAATGCTCACCAAATTTATTTTGTAAATTTGAAAACAAAA TATTTAGTAGAATTACCTCTTTTAATTCCCAACTGTGTTGGAGGAAATCCATAATGCACATAAAACAGCAAACCTACTTAACTTTTTAAC AAGATTATGGGTATAGTACCAATGTCCAAAGGGAAATGTAACTTGCCTGGAATCATAGGCAACATTTTCTAATTAATCTTTTTTTTTTTT TTTTTTTTTGAGACAAAGTCTTGCTCTGTCACCTAGGCTGGAGTGCAGTGGCTCAATCTCAGCTTACTGCAAACTCCGCCTCCCGGGTTC AAGTGATTCTCGTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCATGCACCACCACACCCGGCCCTAATTAGTCATTATTAAGGAGGA CTGCTCATAAAGGCAGTACCAAATCATCATTCAGATCAGCTTAAGTGAGAAAGCAAAATGATAATCTCTATTGTTAGAGAAATTTTCTTT TCTAGACACCAAGGAATATTTTAAATGATTTTTTATTTTTTCTAGGATGCAGGAACTATGAAAAATGATGACAAGGCATTTAAAAGGGTA TGATCAGTTAAATAGAAGTAGGGTCTGCAAATTGTGCTTAAGGGGAAATAAGCAAAAGAAAGGAAAATAGTAGAACCTTTCATACTAATT AGAAATGTAGTTACCTACCAGAGGGCAATTTTGCTCCATACCAGGAAGCAGTAAATAGCAGTAAATGATCACCTAGGCACTTCTTTCCTG TGAATTTGGTGAGCATTCTTCCAGAAAAGAAGACTAAAAGCAAACAACAACAACAACAAAAAATACCACACCTCAGTAACCTTGTATGCT GCATTATATAATAATGATAGTAAAATTATATTGTTTGGAGTGTACTGTGTCTGTTTGCAAATATACATGCACATTAAACTTTTTTGTTTT TATAATGTCTTAATAGCAATTATGAGTTTATTTTTGTTAAGATTAATTTTTCTATTGTGATGTTTATATTTATTGGCAATTTGTATGCAA CTTTTATATTTTGCTTGTCGGTTTTAAGGTATTTTATTTTTATAGATATTTCTAGCTTTCCTCATTCTTTGTAATAGCAGCAAAGATTAA GATGGAGTGTTAATATACCAACCAAACTACGAATTCCATAAACTCTAGAGTTTGGATTTTTACCAATAAACCATTAACACTATTTTGTAA CTTAGAATATTTAATGTTGTTTATATAGTGGGCATTAAAGACAGTCTTTAGACAGATTTCTACATGTGGAGGGGAGGTGGGGCTTTCCTG TAAGTTTGATCCTTTTTTTCCCCTTTAGTAGCAAACTAACATAACAGATTGGATTTATTTTACCTGACTACAGTTTTGGGGAAACCTGTC AAATAAATAATTGTTACATGCCTTTTTTTTTTAAATTTAAGCACATTGAAACTGCTTAAATGGTCACATTTTTCAGCATTAGGATTAAGA TACCATTTTTGTAGGCCTGGAAAACAAATAGCAAATGATTCAAAATTCATTGAATTGACTTTGAAATGAAACTTTTCCCCCATAATTTGT TATATGGAAGATTTGCTACCCTGATCTTTTCCCTAGCATACTTCTAAAGTTGATTGAATCCCTGAGTATCAATGAAGAAATCAGAGTTTA AGTGGCTAGGGAGAGCCAGGTATAAAGACTGATTAATAGAGTACTTCAGCTAATTAAAAATTTAAATAGTAATAATTTATGAATGTGAAT AAATTGGAAGGCAGCAAAAAGCATGATTATAGAATATTAAGTTCAATTATATATAGACAGTCCAGTTTCCTAGTGAATAGGTCAAGATTA TTTGTTTTGTTTTGTGGCACTATCATAGTTCACTATAACTTCAAACTCCTGGGCTCAGGCTATCCTCCCACCTCAGCCTCTGAAGTAGCT GGGACTACTCACATGCGCCACCATGCCCAGCTAATGGTTTTTTTCTTTAGAGATGGGGGTCACTATACTGCCCAGGCTGGTCTTGAACTC CTAAGCTCAAGTGCTTCTCCCACATCAGCCTCCCAAAGTGCTGGGATTACAGCCATGAGCCACTGCATCTGGCCAAGATCAAGATTATGG ATATTGGTATGTTAACTTTTAAAATAAAAGTACATGGGCTGGGCGCAGTGGCTAACGCCTGTAATCCCAGCAATTTGGGAGGCCGAGGCA GGCAGACCACCTGAGGTCAGGGGTTCGTGACCAGCCTGGCCAACATGGCGAAACCCCGTCTCTACTAAACATACAAAAATTAGCTGGGCA TGGTGGCACATGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCACTTGAACTCGGGAGGCGGAGGTTGCAGTGAGCCAAG ATCGCGCCATTGCACTCCAGCCTGGGCAACAAGAGTGAAACTCCATCTCAGAAAATAAAAATAAAAATAAATAAAAGTACATGAAAAAAG TATATTCCCTTAAGCAGGTAAAATACTTGCATTGTATTTTTACATCATGAATTTGCTTGTTAAGAAATTTCTTTTCTGTAAGTGGTTAAA AGATAAACTGTATTCCATCCTCTGGGTTTTCAATTCTAAATTATTGGAGCTCAATGTATGACATTTTACTGTAGTGTATTCCACTGAGAG GCAAGGAAATGGGAAAGTGTCAGGTAATTATAAATGGGAAAATTTTATTTTTATATGATGTAAAGTTTTACAGTTTAAAATAGATCAGCA TGTGATTTCTTGTAGAGATTAGCCATTTCATTTCTTTTTGCATTTTTGCCAGTTACATTAGTTTGCCCTATGATATACTATTCTGAGATA CTTCAGCCCCGCACACATCAAGTACTAATTGTATACAGATAGTACAGATTTGTACTCTGATTATAAGAATTTGTTACTACTAATTAAAAG CAAATTAATGTGGCTGGGCGTGGTAGCTCACACCTGTAATCCCAGCACTTTGGGTGGGCGGCTGAGGCGGGCGGATCACGAGGTCAGGAG TTGGAGACCAGCCTGCCCAATATGGTGAAACCCTGTCTCTACTAAAATTACAAAAATTAGCTGGGCTTGGCGGTACGTGCCTGTAATCCC AGCTACTGGGAAGGCCGAGGCAGGAGAATGGCTTGAACCCAGGAGGCGGAGGTTGCAGTGAGCCAAGATCACACCACTGCACTCCAGCCT GGGCGACAGAGCAAGACTCCGTCTCAAAAAAAAAAAAAGCAAAATATTTTTGCTGTGATTGTATGTCCCCTTTTAAGGATATTTATTGCG CTTATAACCTTAATAGTTGTATTCATTACATTTCAACATGTCCAAGGTTAGCAGACATGTAGTTCCTGAAAACCAACATTTTAAAAGTTG CCTCTGGGCTGGGCATGGTGGCTCACGCCTGTAATCCCTGCACTTTGGGAGGCCGAGGTGGGCGGATCACGAGGTCAAGAGATGGAGACC ATCCTGGCCAACATGCTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCTGGGTGTGGTGGCACACGCCTGTAGTCCCAGCTACTTG GGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGAGGCGGAGGTTGCAGTGAGCCAAGATTGCACCGCTGCACTCCAGCCTGGCAACAGA GCAAGACTCCATCTCAAAACAAACATACAAACAAAAAAAGGTGCCTCTGGTCCTGTGTTTTCTTTTTCCTTCTGAAAGTTCATAGAAACC TGGCATATAGAGCTTATTTTGCTGTTTTAACTGGTTGGCTCCACAAATCCTGCTACCTGACATCAGTACAGCTTGACCGCAGTGAAGTAC TTGATGGCTTGTTCATGTTTAGTTCACCTCTTTAGAAAGAAAGCTTTGTGGCCAGGTGCAGTGGCTCACACCTGTAATCCCAACACTTTG GGCAGCTGAGGTGAGCAGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGCAAAACCCTGTCTCTTCTAAAAATACAAA AATTAGCCGGGTGTGGTGGCGGAGGATGCAGTGAGCCAAGATCGTGCCACTGCACTCCAGCCTGGGCAACAGAGTGAGACTCTGTCTCAA AAAAAAAAAAAAATCGTTGTGCAGTAATAGATCATCCCAAAAAAGAATTGCCATGAACAGCGTTATGCGTAGAAAACAGATGGAAGTGTT GGTCATTAGAGCCTTGCTTTTTAAATTTTATTCTTTCCAAAAATTGGCGGTATGCTATCTATAATTTTATGTTTGATGTTGAAGAGGCAA CACCAGAGACTAGAGAGGGAGATTACTCTGATATTTAGTGCCTAAAACTTTCATCTTGGCCGGGCACGGTGGCTCACACCTGTAATCCCA GCACTTCGGGAGGCCGAGGCAGGCTGATTACCTGAGGTCAGGAGTTCGAGACCAGCCTGGACAACATGGCAAAACCCGTCTCTACTAAAA ATACAAAAATTAGCCAGGCATGGTGGTGGGCGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCGAGAGAATCGTTTGAACCCGGTAGGC GGAGGTTGCAGTGAGCCGAGATCATGCCACTGCACTCCAGCCTGGGCGACAAGAGTGAAACTCCGTCTCAAAAAATAATAATAATTTTAA AAATAAAAGACAAAACTTTCATCTTTATTTCATGGCTTTATTTCATCTTTATTTCATTTTTGGTTGGGAAAACAAACAAAAATCTCTTAA GTTAGTCCTTTAATAGTCTTTTTAGAACCAAAGAAGGAAAGACTGCAAAAATGTTGCATACGTGACTCTTTATTGTCAGAATCTGTAGAA ACTGGAGGTCTTTGTAAAGAAATAGACTAGTAGGATTGTGAGAATATATAGTGAGGGGGGATTTAGGATAAGGCTTCCTTGCTGGGATCC TTGGACAGAAACCTTACAATTGTTTAATATTTGCAGAGTAAAAGAGCAGCTATTGCTATTTGAACCTACAGAAGAGACCTAAGACGAGCG TCTCTGTAATCTAAATTTATATGATAATGTTGTCCCAGACCCAAAGGCACACCTATTCTCAGTAACTTAGAGAAGTCTTGGAAGTTGCTT CTGAATTACAGTAAAGAAATTAAATGAAGTCTTTATCCTTAAATAGGGCCAGGCATTGCTATCAACATAGTGTCTTTGGTTTTCCCCTTT AAATAGAAAACACCAAGCAGGGCCTTTCCAGACAATGTAGTCTTTCCTGTAAAGAAAATGGTTTTGGTGTGGGATTTGGTAAAAACACTG GTTAGTTTGTAATGAAGAAAGAATTTTGGCATAGACAGTCCGACCCAGTTCATGGATACAGTTTGATCCCAGGGAGTTTAACAAAAGGAA GCTTTGGTTTTGCTAGCAACAGACTTGATCTTCTATAGTAATTAATTGCAATTAAGGTTTTCCAGGAGCTTTCTCATTTCTTAGCCCAGG GTCCAACCCCATTCCCTCTTTAAAAAAGAAAGAATAGGCCGGGAGCAGTGGCTCATGCCTGCAATCCCAGCACTTTGGGAGGCCAAGGCA GGTGGATCACAAGGTCAGGAGTTTGAGACCAGCGTGGCCAATATGGTGAAACCCTGTCTCTACTAAAAATACAAAATTAGCTAGGCGTGG TGGCAGGCGCCTGAGGCTGAGGCAGGAGAATCCTGCTAGTCTGAATTACAATAAGGAAATTAAATGAAGGATTTATCTTTAATAGAGCCA GGCATTGCTATCAACATAACATGTTTGGTTTTCCCCTTTAAATAGAAAACACCAAGCAGGGCCTTTCCAGACAAGGTAGTCTGGAACCCA GGAGGCGGAGGTTGCAGTGAGCCGAGATCCCACCATTGCACTCCAGCCTGGGTGGCAGAGTGAGACTCCGTCTCAAAAAAAAAAAAAAGA AGGAATAGGAAAAGGACTTAGAGGCAGTTGATATAGAATTCTACTGGGGGTAAATGACACTCTCAAAATACTTGGGAAAGAAGAATCACA TGCCACAAGCTATAGCTTGATTAATATTTTAGCATGTTTTCCATGTTTGTATTCTAAAGTTTGTTTCCTTTGACATTCCATTATCTTACT TACTAGAGTGCCACCATTCTTATTTGTAATACAATCAGTGTTTTATGCCATTTGTGAATCACACAATTGTTCTTTTTTCCCCATCACACA CACTCACACACAAACACACACACTGTTAAAAATAAAAGAGGGGAAGGATAAAACAAAAATAGATAGAATGATGATTATTACAATGTAACT TTAACATATATGAAGAGAAATTCTAACTCAGTTAAGTGAGAATTAAGATTGAAAGTATTAATGTTGCAAGTATTATCTCTAGCCATGGAA TTTTTTGCTGGCTATAGAATGCTAATGTGAACAGAGTATATATCAGGAATATGATGTATTATGGCACAGTGATAATATTATTGTTGATAT TAGCCAGATGTGGTGGTTTGCACCTGTAGTCCGAACTTCTCAGGAGGATGAGGCAGGAGGATAGTTGAGCCCAGGAGTTTAAAGCAAGCC TGGGCAATACAGCAAGACCCCAATCTTTAAAATAAATAAATAAATAAGAATTATTCTTGAAAGTAATATTCTAACCTTCTGCCAACCAAC AGAGATCCTCATATTCTTAAAGAAAATTAATATAGCTTATGGTTTTGATAAATTGGACTCTGATTTAAACTTTAAAATGTTATGACTTTT ATTCTGATACATGGCTTCTAAAATATGTAAAAAATTATATTGAATGAATTAATACTTAACCTGTTCATTTCTCTTAATTTATGTATTTAT TCTGACTTTATTATACAGCTTATGTCTCACATCTGCCTTCTTGATATGTGCAAAATATTGTGTAAAAATAGTTTAAAACTCATCCCAGTT CCTAGTCAAGCGTGGGCTATAAGAGAGAAGGCTTAAGGTGTTCTTTAATGGAGGAACTTTTGAAAGATCACAAATGGAAAAAGCCTATTG AGAATTTATTGCCTTTGAGAGTAGAAAGGGCTCTAGAATATGAGCCAGAGACTTGGAATTTAGTAATAGGTCTCCCACTGATTTGCTCCG TGTCCTTAGGCAATTCGTTTAATCTCTGTGTGCCTAGTTTCCCCTTGTAAATAAGAGTGGTAATACCTGTCCTCACCTACCTCACTAAAT TGTTGGAGTTCTTTTGTTCTGAGTCAGGGTCTCACTCTGTTGCCCAGGCTGAACTACAGTAGTGTGATCATAGCTCACTACAGCCTCCAA CTCCTGGGCCCAAACTATCCTCCTGCTTCAGCCTCCCAAGTAGCTGGGACTAGAGGTACATGCCACCACACCCAGCTAATTATTTTCTTT TATTGCAGAGATGGGGTCTCACATGTTGCCAAGGCTGATCTCTAACTCCTGAGCTCAAGCAGTCCTCCTGCCTCAGCCACCCAAAGTGCT GGGATTATAGGCATGATCACTAAATTGTTGTAAGAATAAGATAATGTTTGCGGAAGCATTTGAGTTCTCCAAAGGAAAAGCTATTCAGAC GTTCAAGATAATAGAAGAGTGTTGTGTGAAGGATTCCTTTCCAGTTTGCCTCTGTGAAAATGTCTTTGTTGTAGATCATTTTATGAAATA GGAATAAGAGAAACATAGGCCTTATCATGGTGTAGTGTTCACTTACAAACATATCCTGTTGTTTCTTCCCTGCAAGATATCCAGCACACA GGCTGAATTTTTCTTTATAATAATCCTTGGCAAAAGCATAACTTTTCAAAAACCAAATGATTTTAGTGGTGCTATGGCAGCTGCAGTTTT GAGTTAGATTAATGTGGTGAAAACCATCAAATACTTAGAAATTGACTGGGTGCGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGC CGAGGTAGGTGGATCACTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGCAAAACCCCGTCTCTACTAAAGATACAAAAATTAG CTGGGCACGATGGAGGGTGCCTGTAATCCCAGCTACTCGGGAGGCTAAGGTGGGAGAATTGCTTGGACCCAGGTGGCAGAGGTTGCAGTG AGCCAAGATTGTGCCACTGCACTCCAGCCTGGGCAACAAAGCGAAGCTCTGTCTCAATAAAAAAAAAAATAATAATAATAAAATACAAAT ACTTAGAAATTAACTTCGCCTTTGCCTTCAGGCACTTTTGCTACATGTTAGCATCAGAGGCTATTGTACAACTAGATGGTTATTCCCTGT TTCTTGGCCGATTTTTGGTACCTTTCTTTGAAGAAGAGGGTTAGATTTTAAGAAAGAAAGTGTGCTTATTTCACTCATGTCTTTGCAGAA TTTAACTTTGCTTTACTTTAAAAATTCCAATCATCATGTACCTATAAAGGTTAAAATATAGTGAAAGTTTCTGCTTCATGTGAATTCAAT TCTGAGCACCTGCAGGTCATATCAGGTGTCTGATGCAGTTACCTTTATAGATCGTGGCAGGTCCTTACATTTCAACAGGCTTATGCATTT CCATGGGGGGAAGAGATTCTGTTTCTAGGAAATTACAAAGGGCACACCACTGCAGGGAGTGTAAACAATTCTTTGTTGCAACAGACAAGA TTTTTTTTAAAAAAAGAAAAAAGGATGCATTTTAGGTACACAGGGTATGGACGCATTCAACATTTACTTTTATCTCCACAGATGCCAACC TCCCCTTGTTGCAGGCAGTTGGGCTTTTCCAACTCATTGCTAACAAAGCTGGCATCTGCATTAATTTCAATGAGAATTTCAAGTACTGAA GATGAAAAGTTGGGGAGATTCATGTTTGAAAAATGAAAAATGAACAAAAAATCCACCTTGTGCAGTGAGATAGCTAACGCTGATATATCA GGAATAATTTTAAACTATTTTTGCTGTAATGTGTAGCTTTAATGTCTCTTTTCAGTTATGGACCCATAAAAGTATTCCTATATCTTGTGA ATAAAGATCATTCTTGTGGACTAGTACGTGGATGCATTCATAGGCTTTGGGAAGCAGTGGTGTGCGTATGTGTGTCTATATCAATATTTT ATGTTTATAACTCTGCGTATTAAGTTTATATAGAAAAAAATAATGTCTTTCTTTAGTGTTTGGGGGACTCAATGGTAATATGACCATTGC AGTGTAATCTGACTGCTCACTCTAGAGAACACTTCTGTTATACACAATGCACATACAAACATACACCCCTAAAGCGTAGCTAACTGCTCC CACTAGATAATTGCTGCTAAAAACAAAACAAAACAAAACAATACAAAACAAAAAAAACCCTAAGTAATGGAGGAAGAAATAGCATTCTTT TAAAAGGGGCTTTTCTGAAGAGTAAAATGTAAATACAGGACATGTGGGGAGGGTGGGGCCGCCTGCAAAATGTCCTGAAGATGGACAAAT AGCCTTTTAAATTCTACTTTTTAACCATCTTTACCGTGTGTGCCTATTTGTATTGCAGATGTGAACTACTATTTTTGGAGGTTGATATCA GTATGTTTTGAAACTGAATTATTACATAAAATCAGAGTAACCTCTTTCTCCATCCTCCTTTTCCACACTATTCTTGCCAAATATTTCTAC TGAAACCCAGTTTCAGCAAGGCAAAATGATGGGACTCTCAAACCTCCCTCCTCATCTTCCCTTCCCCTCTGTCTTATGCCTGGCCTGGCC TTTTTTGTTGTTGTTGGCTTTTCATAAGTAAGAAAAATTTATTGTAGTATTTCAAGACTGCAGAATTTCAAGTGTATATCTATAAATCTT TTTTTAAAATCTTCGGCTACACAGTAACATCAATTAAAACAGAAGAGTGAGTCTAAGTCTGTAATATGCTGTAGGACCAGATAAGATTTT GAATGAGACTAAACTTGACTGCCATATTTTAAGAGGAAATTGAAACTTTATGGTGGAGAATGGATGAGAGCAAGTCTATGATATATATGT AGTCATTGTATAATTAGAAACACCAAATGCTGAATCCTATCACTGTGTTCTTGGGGGCCAGGCCTTGGATTTGGTTGTCATTTAAACTCC TTGAAGATTATATGTAATTATAATGAGCAGAAGGCAAATAAAGTTTTTGAACAAAAGTCCTTGTTTTCAGTATTTAAAATTTGGTAATAT ATTTTCTTTTTCAGTTAAACTATCTTCCCCACAAAAAATATTATACTTCAGTTAAACTATCTTCCCCACAGAAATTATTATACTACGAAC AAGTTATGAGTGAGACTGAGAAGCTTGAAGAAGCTGGTTTTTAAGCAGCTCATATAATATTTTGTGTTAAAGAAAGTGTCATTGTTTCCT GTTGGGAGGCAAATAACAACAACAACAAAAGAAATTGTCATGATTCTTTCTGAGCCAAACTGTCACGAAATGTTCTGTGACAGAACCACT ACTCTTTTTTCTGCCATTCTGCCTACTGGAGAGTTCTATGTTGTATTTGTTTTTAATCCTTGATTTTAAAAATATTAATGGTTTTAGTGT >6279_6279_2_ARHGEF2-AGO3_ARHGEF2_chr1_155927504_ENST00000313667_AGO3_chr1_36432556_ENST00000373191_length(amino acids)=1367AA_BP=571 MSRIESLTRARIDRSRELASKTREKEKMKEAKDARYTNGHLFTTISVSGMTMCYACNKSITAKEALICPTCNVTIHNRCKDTLANCTKVK QKQQKAALLKNNTALQSVSLRSKTTIRERPSSAIYPSDSFRQSLLGSRRGRSSLSLAKSVSTTNIAGHFNDESPLGLRRILSQSTDSLNM RNRTLSVESLIDEEVIYSELMSDFEMDEKDFAADSWSLAVDSSFLQQHKKEVMKQQDVIYELIQTELHHVRTLKIMTRLFRTGMLEELHL EPGVVQGLFPCVDELSDIHTRFLSQLLERRRQALCPGSTRNFVIHRLGDLLISQFSGPSAEQMCKTYSEFCSRHSKALKLYKELYARDKR FQQFIRKVTRPAVLKRHGVQECILLVTQRITKYPLLISRILQHSHGIEEERQDLTTALGLVKELLSNVDEGIYQLEKGARLQEIYNRMDP RAQTPVPGKGPFGREELLRRKLIHDGCLLWKTATGRFKDVLVLLMTDVLVFLQEKDQKYIFPTLDKPSVVSLQNLIVRDIANQEKGMFLI SAAPPEMYEVHTASRDDRSTWIRVIQQSVRTEVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFKV SIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWK MMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQ TVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDP FVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAG MPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLG GINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPT RIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCS HAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQAL -------------------------------------------------------------- >6279_6279_3_ARHGEF2-AGO3_ARHGEF2_chr1_155927504_ENST00000313667_AGO3_chr1_36432556_ENST00000397828_length(transcript)=2580nt_BP=1712nt ATGTCTCGGATCGAATCCCTCACGCGGGCGCGGATCGACCGGAGCAGAGAGCTGGCGAGCAAGACCCGGGAAAAGGAGAAGATGAAGGAA GCCAAGGATGCCCGCTATACCAATGGGCACCTCTTCACCACCATTTCAGTTTCAGGCATGACCATGTGCTATGCCTGTAACAAGAGCATC ACAGCCAAGGAAGCCCTCATCTGCCCAACCTGCAATGTGACTATCCACAACCGCTGTAAAGACACCCTCGCCAACTGTACCAAGGTCAAG CAGAAGCAACAGAAAGCGGCCCTGCTGAAGAACAACACCGCCTTGCAGTCCGTTTCTCTTCGAAGTAAGACAACCATCCGGGAGCGGCCA AGCTCGGCCATCTACCCCTCCGACAGCTTCCGGCAGTCCCTCCTGGGCTCCCGCCGTGGCCGCTCCTCCTTGTCTTTAGCCAAGAGTGTT TCTACCACCAACATTGCTGGACATTTCAATGATGAGTCTCCCCTGGGGCTGCGCCGGATCCTCTCACAGTCCACAGACTCCCTCAACATG CGGAACCGAACCCTATCCGTGGAATCCCTCATTGACGAAGAGGTAATCTACAGTGAGCTGATGAGTGACTTTGAGATGGATGAGAAGGAC TTTGCAGCTGACTCTTGGAGTCTTGCTGTGGACAGCAGCTTCCTGCAGCAGCATAAAAAGGAGGTGATGAAGCAGCAAGATGTCATCTAT GAGCTAATCCAGACAGAGCTGCACCATGTGAGGACACTGAAGATCATGACCCGCCTCTTCCGCACGGGGATGCTGGAAGAGCTACACTTG GAGCCAGGAGTGGTCCAGGGCCTGTTCCCCTGCGTGGACGAGCTCAGTGACATCCATACACGCTTCCTCAGCCAGCTATTAGAACGCCGA CGCCAGGCCCTGTGCCCTGGCAGCACCCGGAACTTTGTCATCCATCGCTTGGGTGATCTGCTCATCAGCCAGTTCTCAGGTCCTAGTGCG GAGCAGATGTGTAAGACCTACTCGGAGTTCTGCAGCCGCCACAGCAAGGCCTTAAAGCTCTATAAGGAGCTGTACGCCCGAGACAAACGC TTCCAGCAATTCATCCGGAAAGTGACCCGCCCCGCCGTGCTCAAGCGGCACGGGGTACAGGAGTGCATCCTGCTGGTGACTCAGCGCATC ACCAAGTACCCGTTACTCATCAGCCGCATCCTGCAGCATTCCCACGGGATCGAGGAGGAGCGCCAGGACCTGACCACAGCACTGGGGCTA GTGAAGGAGCTGCTGTCCAATGTGGACGAGGGTATTTATCAGCTGGAGAAAGGGGCCCGTCTGCAGGAGATCTACAACCGCATGGACCCT CGGGCCCAAACCCCAGTGCCTGGCAAGGGCCCCTTTGGCCGAGAGGAACTTCTGAGGCGCAAACTCATCCACGATGGCTGCCTGCTCTGG AAGACAGCGACGGGGCGCTTCAAAGATGTGCTAGTGCTGCTGATGACAGATGTACTGGTGTTTCTCCAGGAAAAGGACCAGAAGTACATC TTTCCTACCCTGGACAAGCCTTCAGTGGTATCGCTGCAGAATCTAATCGTACGAGACATTGCCAACCAGGAGAAAGGGATGTTTCTGATC AGCGCAGCCCCACCTGAGATGTACGAGGTGCACACAGCATCCCGGGATGACCGGAGCACCTGGATCCGGGTCATTCAGCAGAGCGTGCGC ACGGAGGTGGTTGACTCAATGGTTCAGCATTTTAAAGTAACTATATTTGGAGACCGTAGACCAGTTTATGATGGAAAAAGAAGTCTTTAC ACCGCCAATCCACTTCCTGTGGCAACTACAGGGGTAGATTTAGACGTTACTTTACCTGGGGAAGGTGGAAAAGATCGACCTTTCAAGGTG TCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACGGACCTTGCCTGAGCCACTGGAATTAGACAAG CCAATCAGCACTAACCCTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCATGAAATACACACCTGTGGGGCGTTCATTTTTC TCCGCTCCAGAAGGATATGACCACCCTCTGGGAGGGGGCAGGGAAGTGTGGTTTGGATTCCATCAGTCTGTTCGGCCTGCCATGTGGAAA ATGATGCTTAATATCGATGAAAGAGACCTCTGGCAGCAGTGTGGAGAATAGATAGAGGAGAAAAAACTAATCTGAGAAGCCAGTTAGGAG GCTTTTCAATCACTAGTTCAGGTTTCAGTCTACATGTTACTTCCTTGAGAAGCAGTGTTTGACACCCTTCTCCCCCAATCCAGCCATCCC CCAAGTCTGAGTTAGGTATTTCTCTTCTGTATTCCCATAGCACAGTGTAATTCCCCTATAATAGCATGTATCACCTTGAATTATGGGTGT TTATTGTTCTGTCTCTCCTGTTAGAACGAAAGCTCCATGAAGGGATTGTCATTTTATTCACCAGTGTACCCTCTATGCCCAGCACAACTT >6279_6279_3_ARHGEF2-AGO3_ARHGEF2_chr1_155927504_ENST00000313667_AGO3_chr1_36432556_ENST00000397828_length(amino acids)=736AA_BP=571 MSRIESLTRARIDRSRELASKTREKEKMKEAKDARYTNGHLFTTISVSGMTMCYACNKSITAKEALICPTCNVTIHNRCKDTLANCTKVK QKQQKAALLKNNTALQSVSLRSKTTIRERPSSAIYPSDSFRQSLLGSRRGRSSLSLAKSVSTTNIAGHFNDESPLGLRRILSQSTDSLNM RNRTLSVESLIDEEVIYSELMSDFEMDEKDFAADSWSLAVDSSFLQQHKKEVMKQQDVIYELIQTELHHVRTLKIMTRLFRTGMLEELHL EPGVVQGLFPCVDELSDIHTRFLSQLLERRRQALCPGSTRNFVIHRLGDLLISQFSGPSAEQMCKTYSEFCSRHSKALKLYKELYARDKR FQQFIRKVTRPAVLKRHGVQECILLVTQRITKYPLLISRILQHSHGIEEERQDLTTALGLVKELLSNVDEGIYQLEKGARLQEIYNRMDP RAQTPVPGKGPFGREELLRRKLIHDGCLLWKTATGRFKDVLVLLMTDVLVFLQEKDQKYIFPTLDKPSVVSLQNLIVRDIANQEKGMFLI SAAPPEMYEVHTASRDDRSTWIRVIQQSVRTEVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFKV SIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWK -------------------------------------------------------------- >6279_6279_4_ARHGEF2-AGO3_ARHGEF2_chr1_155927504_ENST00000313695_AGO3_chr1_36432556_ENST00000324350_length(transcript)=2999nt_BP=1743nt GGGATCCCGGGAGGGAGCGGAGCGGACCTGGGCTTGGTCGCCTCCAAGCCGGCGGGACCGAGTGCTTTAGGCCGCTTGAAAGAAAGTTGC TCCGACCCGGGAAAAGGAGAAGATGAAGGAAGCCAAGGATGCCCGCTATACCAATGGGCACCTCTTCACCACCATTTCAGTTTCAGGCAT GACCATGTGCTATGCCTGTAACAAGAGCATCACAGCCAAGGAAGCCCTCATCTGCCCAACCTGCAATGTGACTATCCACAACCGCTGTAA AGACACCCTCGCCAACTGTACCAAGGTCAAGCAGAAGCAACAGAAAGCGGCCCTGCTGAAGAACAACACCGCCTTGCAGTCCGTTTCTCT TCGAAGTAAGACAACCATCCGGGAGCGGCCAAGCTCGGCCATCTACCCCTCCGACAGCTTCCGGCAGTCCCTCCTGGGCTCCCGCCGTGG CCGCTCCTCCTTGTCTTTAGCCAAGAGTGTTTCTACCACCAACATTGCTGGACATTTCAATGATGAGTCTCCCCTGGGGCTGCGCCGGAT CCTCTCACAGTCCACAGACTCCCTCAACATGCGGAACCGAACCCTATCCGTGGAATCCCTCATTGACGAAGAGGTAATCTACAGTGAGCT GATGAGTGACTTTGAGATGGATGAGAAGGACTTTGCAGCTGACTCTTGGAGTCTTGCTGTGGACAGCAGCTTCCTGCAGCAGCATAAAAA GGAGGTGATGAAGCAGCAAGATGTCATCTATGAGCTAATCCAGACAGAGCTGCACCATGTGAGGACACTGAAGATCATGACCCGCCTCTT CCGCACGGGGATGCTGGAAGAGCTACACTTGGAGCCAGGAGTGGTCCAGGGCCTGTTCCCCTGCGTGGACGAGCTCAGTGACATCCATAC ACGCTTCCTCAGCCAGCTATTAGAACGCCGACGCCAGGCCCTGTGCCCTGGCAGCACCCGGAACTTTGTCATCCATCGCTTGGGTGATCT GCTCATCAGCCAGTTCTCAGGTCCTAGTGCGGAGCAGATGTGTAAGACCTACTCGGAGTTCTGCAGCCGCCACAGCAAGGCCTTAAAGCT CTATAAGGAGCTGTACGCCCGAGACAAACGCTTCCAGCAATTCATCCGGAAAGTGACCCGCCCCGCCGTGCTCAAGCGGCACGGGGTACA GGAGTGCATCCTGCTGGTGACTCAGCGCATCACCAAGTACCCGTTACTCATCAGCCGCATCCTGCAGCATTCCCACGGGATCGAGGAGGA GCGCCAGGACCTGACCACAGCACTGGGGCTAGTGAAGGAGCTGCTGTCCAATGTGGACGAGGGTATTTATCAGCTGGAGAAAGGGGCCCG TCTGCAGGAGATCTACAACCGCATGGACCCTCGGGCCCAAACCCCAGTGCCTGGCAAGGGCCCCTTTGGCCGAGAGGAACTTCTGAGGCG CAAACTCATCCACGATGGCTGCCTGCTCTGGAAGACAGCGACGGGGCGCTTCAAAGATGTGCTAGTGCTGCTGATGACAGATGTACTGGT GTTTCTCCAGGAAAAGGACCAGAAGTACATCTTTCCTACCCTGGACAAGCCTTCAGTGGTATCGCTGCAGAATCTAATCGTACGAGACAT TGCCAACCAGGAGAAAGGGATGTTTCTGATCAGCGCAGCCCCACCTGAGATGTACGAGGTGCACACAGCATCCCGGGATGACCGGAGCAC CTGGATCCGGGTCATTCAGCAGAGCGTGCGCACGGAGGTGGTTGACTCAATGGTTCAGCATTTTAAAGTAACTATATTTGGAGACCGTAG ACCAGTTTATGATGGAAAAAGAAGTCTTTACACCGCCAATCCACTTCCTGTGGCAACTACAGGGGTAGATTTAGACGTTACTTTACCTGG GGAAGGTGGAAAAGATCGACCTTTCAAGGTGTCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACG GACCTTGCCTGAGCCACTGGAATTAGACAAGCCAATCAGCACTAACCCTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCAT GAAATACACACCTGTGGGGCGTTCATTTTTCTCCGCTCCAGAAGGATATGACCACCCTCTGGGAGGGGGCAGGGAAGTGTGGTTTGGATT CCATCAGTCTGTTCGGCCTGCCATGTGGAAAATGATGCTTAATATCGATGAAAGAGACCTCTGGCAGCAGTGTGGAGAATAGATAGAGGA GAAAAAACTAATCTGAGAAGCCAGTTAGGAGGCTTTTCAATCACTAGTTCAGGTAAGAGATGGTGATGGTCTAATGTGGGATGGAGAGGA AGGATTAAGCTGAAAAAATAGGTTTAAGAACCATGTCCAGAAAAAAAAAACTTTGGGTGTAGTACTGGTACATGGAACGGATTGGAAAAA AATAGACCAGAGCTTTACTAGATTTTTGAAAGAATTGTTTTTGCAAATAAACTACAAGCCTGGCATATCAGTCAAGGTTCAGAACCTAGA GAAGCAGAACCAGTACGAAGTATAGAGAGAGAGTTTATGCAATTGTAGGGGCTAGCTAGGCAAGTCTGAAATTTTGGGGGCAGGCTGTCA GGAAGGGCAGGGAAATTCAGGCATGGGCTGAAGCAGTTATCTATAAGTGGAATTTCTTGCTCTCAGGGAAGCTTCAGCCCTACTTTTAAG ACCTTTCACCTAATTGAATCAGGCCCATCCACATTATTCAGGATAATCTCCATTACTTAAAGTCAACAGATTATGGATTTTAATTACATC TACAAAATACCTTCATAGCAACACCTAGATTAGTGTTTGATTAAACAAATGGCAGCTGGTAGCCTAGCAAGTTAACACATTAAAAACAAC ACCTGCCATGATGGCTTACACTTGTAATCCCAGCACTTTGGGAGGCCAAAGTGGGAGGATCACTTGAGATTAGGAGTTTGCGATCAGGCT >6279_6279_4_ARHGEF2-AGO3_ARHGEF2_chr1_155927504_ENST00000313695_AGO3_chr1_36432556_ENST00000324350_length(amino acids)=709AA_BP=544 MKEAKDARYTNGHLFTTISVSGMTMCYACNKSITAKEALICPTCNVTIHNRCKDTLANCTKVKQKQQKAALLKNNTALQSVSLRSKTTIR ERPSSAIYPSDSFRQSLLGSRRGRSSLSLAKSVSTTNIAGHFNDESPLGLRRILSQSTDSLNMRNRTLSVESLIDEEVIYSELMSDFEMD EKDFAADSWSLAVDSSFLQQHKKEVMKQQDVIYELIQTELHHVRTLKIMTRLFRTGMLEELHLEPGVVQGLFPCVDELSDIHTRFLSQLL ERRRQALCPGSTRNFVIHRLGDLLISQFSGPSAEQMCKTYSEFCSRHSKALKLYKELYARDKRFQQFIRKVTRPAVLKRHGVQECILLVT QRITKYPLLISRILQHSHGIEEERQDLTTALGLVKELLSNVDEGIYQLEKGARLQEIYNRMDPRAQTPVPGKGPFGREELLRRKLIHDGC LLWKTATGRFKDVLVLLMTDVLVFLQEKDQKYIFPTLDKPSVVSLQNLIVRDIANQEKGMFLISAAPPEMYEVHTASRDDRSTWIRVIQQ SVRTEVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLE -------------------------------------------------------------- >6279_6279_5_ARHGEF2-AGO3_ARHGEF2_chr1_155927504_ENST00000313695_AGO3_chr1_36432556_ENST00000373191_length(transcript)=20890nt_BP=1743nt GGGATCCCGGGAGGGAGCGGAGCGGACCTGGGCTTGGTCGCCTCCAAGCCGGCGGGACCGAGTGCTTTAGGCCGCTTGAAAGAAAGTTGC TCCGACCCGGGAAAAGGAGAAGATGAAGGAAGCCAAGGATGCCCGCTATACCAATGGGCACCTCTTCACCACCATTTCAGTTTCAGGCAT GACCATGTGCTATGCCTGTAACAAGAGCATCACAGCCAAGGAAGCCCTCATCTGCCCAACCTGCAATGTGACTATCCACAACCGCTGTAA AGACACCCTCGCCAACTGTACCAAGGTCAAGCAGAAGCAACAGAAAGCGGCCCTGCTGAAGAACAACACCGCCTTGCAGTCCGTTTCTCT TCGAAGTAAGACAACCATCCGGGAGCGGCCAAGCTCGGCCATCTACCCCTCCGACAGCTTCCGGCAGTCCCTCCTGGGCTCCCGCCGTGG CCGCTCCTCCTTGTCTTTAGCCAAGAGTGTTTCTACCACCAACATTGCTGGACATTTCAATGATGAGTCTCCCCTGGGGCTGCGCCGGAT CCTCTCACAGTCCACAGACTCCCTCAACATGCGGAACCGAACCCTATCCGTGGAATCCCTCATTGACGAAGAGGTAATCTACAGTGAGCT GATGAGTGACTTTGAGATGGATGAGAAGGACTTTGCAGCTGACTCTTGGAGTCTTGCTGTGGACAGCAGCTTCCTGCAGCAGCATAAAAA GGAGGTGATGAAGCAGCAAGATGTCATCTATGAGCTAATCCAGACAGAGCTGCACCATGTGAGGACACTGAAGATCATGACCCGCCTCTT CCGCACGGGGATGCTGGAAGAGCTACACTTGGAGCCAGGAGTGGTCCAGGGCCTGTTCCCCTGCGTGGACGAGCTCAGTGACATCCATAC ACGCTTCCTCAGCCAGCTATTAGAACGCCGACGCCAGGCCCTGTGCCCTGGCAGCACCCGGAACTTTGTCATCCATCGCTTGGGTGATCT GCTCATCAGCCAGTTCTCAGGTCCTAGTGCGGAGCAGATGTGTAAGACCTACTCGGAGTTCTGCAGCCGCCACAGCAAGGCCTTAAAGCT CTATAAGGAGCTGTACGCCCGAGACAAACGCTTCCAGCAATTCATCCGGAAAGTGACCCGCCCCGCCGTGCTCAAGCGGCACGGGGTACA GGAGTGCATCCTGCTGGTGACTCAGCGCATCACCAAGTACCCGTTACTCATCAGCCGCATCCTGCAGCATTCCCACGGGATCGAGGAGGA GCGCCAGGACCTGACCACAGCACTGGGGCTAGTGAAGGAGCTGCTGTCCAATGTGGACGAGGGTATTTATCAGCTGGAGAAAGGGGCCCG TCTGCAGGAGATCTACAACCGCATGGACCCTCGGGCCCAAACCCCAGTGCCTGGCAAGGGCCCCTTTGGCCGAGAGGAACTTCTGAGGCG CAAACTCATCCACGATGGCTGCCTGCTCTGGAAGACAGCGACGGGGCGCTTCAAAGATGTGCTAGTGCTGCTGATGACAGATGTACTGGT GTTTCTCCAGGAAAAGGACCAGAAGTACATCTTTCCTACCCTGGACAAGCCTTCAGTGGTATCGCTGCAGAATCTAATCGTACGAGACAT TGCCAACCAGGAGAAAGGGATGTTTCTGATCAGCGCAGCCCCACCTGAGATGTACGAGGTGCACACAGCATCCCGGGATGACCGGAGCAC CTGGATCCGGGTCATTCAGCAGAGCGTGCGCACGGAGGTGGTTGACTCAATGGTTCAGCATTTTAAAGTAACTATATTTGGAGACCGTAG ACCAGTTTATGATGGAAAAAGAAGTCTTTACACCGCCAATCCACTTCCTGTGGCAACTACAGGGGTAGATTTAGACGTTACTTTACCTGG GGAAGGTGGAAAAGATCGACCTTTCAAGGTGTCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACG GACCTTGCCTGAGCCACTGGAATTAGACAAGCCAATCAGCACTAACCCTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCAT GAAATACACACCTGTGGGGCGTTCATTTTTCTCCGCTCCAGAAGGATATGACCACCCTCTGGGAGGGGGCAGGGAAGTGTGGTTTGGATT CCATCAGTCTGTTCGGCCTGCCATGTGGAAAATGATGCTTAATATCGATGTTTCTGCCACTGCCTTCTACAAAGCACAACCTGTAATTCA GTTCATGTGTGAAGTTCTTGATATTCATAATATTGATGAGCAACCAAGACCTCTGACTGATTCTCATCGGGTAAAATTCACCAAAGAGAT AAAAGGTTTGAAGGTTGAAGTGACTCATTGTGGAACAATGAGACGGAAATACCGTGTTTGTAATGTAACAAGGAGGCCTGCCAGTCATCA AACCTTTCCTTTACAGTTAGAAAACGGCCAAACTGTGGAGAGAACAGTAGCGCAGTATTTCAGAGAAAAGTATACTCTTCAGCTGAAGTA CCCGCACCTTCCCTGTCTGCAAGTCGGGCAGGAACAGAAACACACCTACCTGCCACTAGAAGTCTGTAATATTGTGGCAGGGCAACGATG TATCAAGAAGCTAACAGACAATCAGACTTCCACTATGATCAAGGCAACAGCAAGATCTGCACCAGATAGACAAGAGGAAATTAGCAGATT GGTAAGAAGTGCAAATTATGAAACAGATCCATTTGTTCAGGAGTTTCAATTTAAAGTTCGGGATGAAATGGCTCATGTAACTGGACGCGT ACTTCCAGCACCTATGCTCCAGTATGGAGGACGGAATCGGACAGTAGCAACACCGAGCCATGGAGTATGGGACATGCGAGGGAAACAATT CCACACAGGAGTTGAAATCAAAATGTGGGCTATCGCTTGTTTTGCCACACAGAGGCAGTGCAGAGAAGAAATATTGAAGGGTTTCACAGA CCAGCTGCGTAAGATTTCTAAGGATGCAGGGATGCCCATCCAGGGCCAGCCATGCTTCTGCAAATATGCACAGGGGGCAGACAGCGTAGA GCCCATGTTCCGGCATCTCAAGAACACATATTCTGGCCTACAGCTTATTATCGTCATCCTGCCGGGGAAGACACCAGTGTATGCGGAAGT GAAACGTGTAGGAGACACACTTTTGGGTATGGCTACACAATGTGTTCAAGTCAAGAATGTAATAAAAACATCTCCTCAAACTCTGTCAAA CTTGTGCCTAAAGATAAATGTTAAACTCGGAGGGATCAATAATATTCTTGTACCTCATCAAAGACCTTCTGTGTTCCAGCAACCAGTGAT CTTTTTGGGAGCCGATGTCACTCATCCACCTGCTGGTGATGGAAAGAAGCCTTCTATTGCTGCTGTTGTAGGTAGTATGGATGCACACCC AAGCAGATACTGTGCCACAGTAAGAGTTCAGAGACCCCGACAGGAGATCATCCAGGACTTGGCCTCCATGGTCCGGGAACTTCTTATTCA ATTTTATAAGTCAACTCGGTTCAAGCCTACTCGTATCATCTTTTATCGGGATGGTGTTTCAGAGGGGCAGTTTAGGCAGGTATTATATTA TGAACTACTAGCAATTCGAGAAGCCTGCATCAGTTTGGAGAAAGACTATCAACCTGGAATAACCTACATTGTAGTTCAGAAGAGACATCA CACTCGATTATTTTGTGCTGATAGGACAGAAAGGGTTGGAAGAAGTGGCAATATCCCAGCTGGAACAACAGTTGATACAGACATTACACA CCCATATGAGTTCGATTTTTACCTCTGTAGCCATGCTGGAATACAGGGTACCAGTCGTCCTTCACACTATCATGTTTTATGGGATGATAA CTGCTTTACTGCAGATGAACTTCAGCTGCTAACTTACCAGCTCTGCCACACTTACGTACGCTGTACACGATCTGTTTCTATACCTGCACC AGCGTATTATGCTCACCTGGTAGCATTTAGAGCCAGATATCATCTTGTGGACAAAGAACATGACAGTGCTGAAGGAAGTCACGTTTCAGG ACAAAGCAATGGGCGAGATCCACAAGCTCTTGCCAAGGCTGTACAGATTCACCAAGATACCTTACGCACAATGTACTTCGCTTAAATAGT CCAAGTATATTCTCTGAGAGGAAGTACTGAAAGATGAATTGACATACAACGTATGTTTCCAGTGAAGTCAATTGAGTAAGGACACCTCCA GCCATACAGAAACCAACACTGTGTGGGGGCCAAGGTCTGATCCTTATGTTAATACAAGGAAGATTGTTTACTTCATCAAGGAACACAGCA TCATTATGCAATATGAAACCAGCCAACTGCTTTTTGTGCGGTCTCCTATAGGAAGTATCGCAATTGTTTTGTTTTCATTTCTTGTAGTCT AACCCTTTTAATGCCTTTACCTCAAGTTGCTTGGCAGCACAACTATCTTTGCAAAAAAAAGTAAAGAAAAAGTAAATGATGGTTTAAAAA ATACACACCTTCATGAATAATCAAAGTGATTTTTCAGAATTATGTGTGCAAAAAATTAATGTGCATTCATATATTCTTGTAAAAGGTGTC TGTGTATTTTTAAAATATATACATCCATACTTCATATGCATATATATCTAGATCTGGATTGATAATAGATATATATGTGTCTGTTATATA TTTTAGAGTTCATTCCATTGGGGAATTTTCTTTCCCTTTTATTCTACCCCCACTACCGCCTTTATTTCTCTATTTCCCTTGCCTTCATCA CCTACATTTTTTTCCCAGTCCTACCAGTGACATTCAAATGTTGATGTATCTGGTTCGTTTGAATATAAAATATGGCAAACTAGAATTCTA CTTTTATTTTGCATACCCTACTCCTGACTCCTATCTCATACACAATTCTGAGTTCTCAACTCTTGATATTGCTGTCTTAAGAAACAAAAT TTTATATATATATGTATACATACATACACAGACACAGACACACACATATATATACATAAAATAACTTTCTGTGAGAGTGCGTCTCTCCCC TCCCACTCAGAACATACATTTACCATTTGCGCAATTTGTATATAAGCAGTAGCAACCTGAACTATTCTTTTTCTTTTTTCTTTTTCTTTT CTTTCTTTTTTTTTTTTAATGAGACAGAGCCTCGCTCTGTCACCAGGCTGGAGTGCAGTGGCGAGATCTCGGCTCACTGCAACTTCCGCC TCTCGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGTTTACAGGCATGTGCCACCACACCCAGCTAATTTTTGTATTTT TAGTAGAGACGGGGTTTCACCGTGTTGGCCAGGATGGTCTCGATCTCTTGACCTTGTGATCCACCCGCCTCGACCTCCCAAAGTGCTGGG ATTACAGGCATGAGCCACCGCACCCGGCCTACTATTCTTTTTCTTTAGTGAGTTTGTTAAAGCTGCTATAAATATAAAACCTGTCAGAAG TTGTAACTTTCTCTCTGGTAAGTGATGTGTATTCTGAAGCCTTCTGTTTCTATGGGTTATACATGGAAATTCTTTAAAGGTTTTATAAAG GGTAAATATTTTAAAAGATTAGAGCTCTGTAGGGTTGAGACCTCTGAAATTGAGTAGAGAGAAGAGTTTGTTGAGGGATTTTTTTGTTTT GTTTTTTGATAGTTTACTTGCTGCCTCTCATACCTTAATGTGATTTTCATATATTTTTTATATATATATATGTATGTGTGTGTATATAAA CACATATGTATGTGTTTGGAAGTATAGCTTCCTTTTCTTTTATATTTATTAGAATAGTGCTTTAATAATTATAGAATTGTATTGGCAGCA TCTTTTATAGAAATATAATCATGTTTATTTTAAGAACTGACAACTTGTTTTTGCTATCTTTTAGTGCAATAAGCAGTTTTAAAGGAAAGT TGTGTCTGCATCTTTACCATGGATAGTAGGAGGAACAGGCACCTCCATAGTTTAAAAGGGCAAAGAATACAGCCTTAATTTCAGAAGGAA AGTTTTGTAATTTTCAGTTTTAAAGCATATCTTTTAAAATTCATCATGATAAAAGGCTGGACGCGGTGGCTCATGCCTGTAATCCTAGCA CTTTGGGAGGCTGAGACAGGTATATCACCGGAGCTCAGGAGTTTGAGACCAGCCTGGCCAACGTGGTGAAACCCCGTCTCTACTAAAAAT ACAAAAATTAGCTGGGCGTGGTAGTGGGCACCTCTAATCCCAGCTACTCGGGAGGCTGAGGCAGGATTGCTTGAACCTAGGAGGCGGAAG TTACAGTGAGCCAAGACTGCACCATTGCACTCCAGCCTGGGCAACAAAACCAAAACTCCGTCTCAAAAGAAAAAAAAATCATAATGAAAA TGAAGTGAAATTGCCTAAATGAGTCCAACTTGAATATTAGAAATAAAGTTGAACTTTTATATAATTGTGAATAGCTTAACATATTTAAAT TATTTGCAAATAGATTGTGTTTATTGAAGAATCATATTGGCTAGATGCCCATTTTCATTTACTAAAATGAATCAGGAAAATGCAAGATGA TATTTTAAAACTTTTGCTAATGTATCACCAGTATAACTTTCCTTTTAAAATTAAGGTGATAGTAACAAAGGAAGTTAGGACTTTGATCAT TTTAAATCAGTTAAATCACTGAAACGTGGGAAATTGTTTTACAAAACTTTTATTGATTACACTTTAAGGTATTAAAAAGTACTATAAAGC TATCAAAACTGAGTTTATCAGTAACATTGGATTCAGGGGAGCTTTGCACTTTGTAACTCATGAAAATTGCATTTTGATTTTTTTTTTTTT TGCACTGGTTCAGAGTATAGATACTACAGATTGTTTCCAGTGGGCATTGTTGTTAGCCTTTCAGAATTCCATCTGCACGTGAAACCTAAT GGATTTAGATCTTTAGTTTCTCTCTTACCTGTAATCCACTATTATTGCCAATTCACTGTATTTTGAGCCTAAAATCTGAGCCCATGTCCT CTGACAGGCATGAAATCTTTTGTCCCTCTGCCAGAAAACTAAGAAAGTACTGTATTTTGTATGTTTATTATTTTGAAGTGTCTGAAATGC AATTTACAACACTGTTGCAAAGAACTTTACAAAAGGTAATATTTGTATCGTATATACATTTTTTCTCCCAGCCTTCTCCCATCTCCTCCA GAAAAATTTCCTATAAAGATGGATTTTTTTACACTGAAATTTTACTGAATATAGTCAGGATCATGGGCAAGAGAAGAAAATAGTATACCC AAGATGATAAAAATTTAATTCGTCTATGCTTGATCAGTGTGAGTAAAACATCTTCCTTTATCATGGGAGCTGCACAGATTCATGTGGGAA ACTTTAGGGAATGACTGTAGATACCCTTTCTCTATGTACTCTCTCACCTAATTTTCAGTCACTCATATATGCTAGAGTGGAGCCCTTAAT TTAAATCTATTTGGAAGGACTTTTTTAAGAGGAAAAATATTTTTTCTAAATTATAAAGCTTTACCTTTTGAGTGATTTCTTTTTTAGAGT GCTCTTACACTAGTCAGCATTGCTAGTTTAAAGTTGATTAACTTGAAAGAGTATGTATACTATATTTCTATTTTGCTAACAAATTGGTAT ATTAATTACCATTGGTTCTTAATTACAAGAAAACTTGTGCTTAGAATTTTAAGATAAAAGGCTAAGTGACAAATGCTTCTTGAAATTTGT CCTATTTATTGTTGCATTTCTGGTGTAGAATTTCTAATCTTTTTTATTTTAAAAAAGTTTTTTTTTTTAAGTTAAACATGAAATTCACAG TGACCCTTCTGCTCCTGCCCTTGCTCACTAACTATATCATGAATGCTAGATTTTGGTCTTCTTTTTTCTGTGATGTATCTTACGAGACTG ACTGTAAAATATCAGTCTGGCAACTAGATAATTGATTTTCATATGAAGAAGAGTTGGGAGTTTAATGTATATTCTTGATGGTTAATGTGT CTACATAAAGTGCTGATACATGTATTATATCACAGTATCAGGTTACTGGCATGGAGGACCATACACTTACAATATTGTAGCTGCTATATT TATTTAAGTAGATTCTGACAGTTACTGCACTAAACAGTAAGGAGATAAGCAGGATTCAAGGCTAGTGTTAGACCCTTTTTTTTCCTAAGA GTAAGGACACGGAATATCAAAGTAACAAAGGGTGCTGCCATTTTAGTTTCAATTTAATATCAGGATATTCTTTGTTTTAGAAATGTAGAT TTTGACTTTTACAGTTTGAAAAAGGGTACCTCAGCCTCTTCAGTACTGGTTTTTTGGCACATTTCAACAGAAATATTAGATTCCCTTTCT TTTTCTTAATAGTGATCTTCTAACAAGTTTCTTGGAAAAACTATCATTCTAAGGGAAATCCCTGTTTATAACCTATTAATATATTTCTAT TCCTAGAAGAGAGTCTAGCAGGGATTCTAGTAGGAATTACTGAGTGTTTTGGAAGGCACTTGATAGAGGCATCTCTGCTTTCCAGCACAG GGATTCTCAGCCTTCTAAAGATCTAGACCAGTTTCCAAGCTAGCTTCTCCACAGCCCACCACTGCCTAGTGTTTGCTTGTGTATTCTCTA ATGGATTTTAGGAGGATAGGCCTTCTGACAGAGTCATGAAAGACTGAAGGCATGTCTAGGGAAATAAAACCTGACTTGCCCTTCAGCAGG AATGACTGGCAGCGGATCTCTGTGTTCAAGGAAAGGGTGAGCGCTAAGCATGCCAGTGATGGATCCGAAGTATTTAGATGGATTGCAGAC CAGGAATTAGAGACCGTTTGTGACTCAAGGAACTTGATGGATCTGTTTAGAGCCCTACATGAATTTGCCAAGGGCAGTGATTTTTATGAA ATTCAAGAAGCAAACGACTTCGATACAGCTAGAATATGTTGCAGTCTTCCTATTTCAAACTTGATTTTAATATTTTTACCAAGAAGTTTA ACTGACAACTCTGCAAAATTTTCATTCAGTATCATTAAACCTGAGTTAAATGTTTGCTTAGCTTATCCTCTTAGATGTTCTTCTGTTGAA CAGGCAGGTTGCCCTTAACAGTAACTTGCTACTTAAATTACCTTTTATTAGTTAGTCAAGCTGCAAAAATATCATTAGTGTGGCGTCTTT ATTTTGGCTTTATCCATATGAAGTATTCATTATTTTCATTCTTTTTGAGAATTCATAAATGTCTTAAAGCTTCAGTAAGAATTGTTGGGA GGTTTGACATCAAGTAACGCCTTCCTGTGTAGCAGTATAACCCTAATTTAGAACTCTTGTTTTCCTATTTCAGTCCTCATATTTGATCAT AGAAAAGCACTTTTGTGATTCTATAGGAGTCAAAAAATCAGCCAAGAGTAGGTAAGTCAGTCAGCACAGAAATCAGAAAGTGAGAATTTT CTCCAAAAAATCTTTTTAAAAAAGTCCTGCTTATACTAAGAACATTCTTGATCCGTTGCAGTGTTAGAAATGACACTGTGATTAGTGAAA GCCAAGCTGAGTCCCAGGAAGCAGGGAGGGGGAGTGTGTGTGTGTGTATATGTATGAGTGTGTATATATATAATCTCACACACACACACA AAGGGAAAAATTATTTTGACTTTTTTCCTACTTTTAAAATGGTACATTTAAGTTTATAATTTTCCATGTCAGTCAACATAATTTTTTAAA CTAAGGTATAATGGTCAAGGCTTGTGCTAATATTACCTACTACTCATTGAAATTTATATTACTTTACCCATCAAAACTAGTACTCCAGAT GTTTACATCATTGATTAAATCTCAAGAATCTTTTGTTCTTAAAATATGGAAGTTAAAGATTTTAATTTGAATTAAAGATAGAAGGATGGT AAATTCAATATAGAGGGTTGAGATTTACCAGTGAGAAACCCTGTTGAAGTATCAGGTAAATGGTGTGACAAAATTAGAATCCTGTCAAAT CACCTATCCAGCCATCGGGGTCCCTTCCTTTTTTAGACTAATTTCTAAGGTAACCAGAATCTAATGTATCTATGTTAGGGTCTCAGTAAA GCAAAGACGTTTGTCAGGGCGTAGACTCTTGAGTTAAATTTTTTAATCATTTTTTAAAGCAAGGCGGTTCTTAGAAAGTGCCTTTTCAGA AGATGGTGCTGTAGATTTTTATTTTTCAAGTAGCACGAAGCTAAGAATTTTAAAGATAAATTATTTTAGAACTCCAAGAGTGTGACAGTT TCATAAAAATAATGTTAGTTGTTGTCTTGAATCTCGTCCAAGGGAACCAAGGAAAGCTTTTATGCAGTAAAGTATCTAGGTAAATGCTCA CCAAATTTATTTTGTAAATTTGAAAACAAAATATTTAGTAGAATTACCTCTTTTAATTCCCAACTGTGTTGGAGGAAATCCATAATGCAC ATAAAACAGCAAACCTACTTAACTTTTTAACAAGATTATGGGTATAGTACCAATGTCCAAAGGGAAATGTAACTTGCCTGGAATCATAGG CAACATTTTCTAATTAATCTTTTTTTTTTTTTTTTTTTTTGAGACAAAGTCTTGCTCTGTCACCTAGGCTGGAGTGCAGTGGCTCAATCT CAGCTTACTGCAAACTCCGCCTCCCGGGTTCAAGTGATTCTCGTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCATGCACCACCACA CCCGGCCCTAATTAGTCATTATTAAGGAGGACTGCTCATAAAGGCAGTACCAAATCATCATTCAGATCAGCTTAAGTGAGAAAGCAAAAT GATAATCTCTATTGTTAGAGAAATTTTCTTTTCTAGACACCAAGGAATATTTTAAATGATTTTTTATTTTTTCTAGGATGCAGGAACTAT GAAAAATGATGACAAGGCATTTAAAAGGGTATGATCAGTTAAATAGAAGTAGGGTCTGCAAATTGTGCTTAAGGGGAAATAAGCAAAAGA AAGGAAAATAGTAGAACCTTTCATACTAATTAGAAATGTAGTTACCTACCAGAGGGCAATTTTGCTCCATACCAGGAAGCAGTAAATAGC AGTAAATGATCACCTAGGCACTTCTTTCCTGTGAATTTGGTGAGCATTCTTCCAGAAAAGAAGACTAAAAGCAAACAACAACAACAACAA AAAATACCACACCTCAGTAACCTTGTATGCTGCATTATATAATAATGATAGTAAAATTATATTGTTTGGAGTGTACTGTGTCTGTTTGCA AATATACATGCACATTAAACTTTTTTGTTTTTATAATGTCTTAATAGCAATTATGAGTTTATTTTTGTTAAGATTAATTTTTCTATTGTG ATGTTTATATTTATTGGCAATTTGTATGCAACTTTTATATTTTGCTTGTCGGTTTTAAGGTATTTTATTTTTATAGATATTTCTAGCTTT CCTCATTCTTTGTAATAGCAGCAAAGATTAAGATGGAGTGTTAATATACCAACCAAACTACGAATTCCATAAACTCTAGAGTTTGGATTT TTACCAATAAACCATTAACACTATTTTGTAACTTAGAATATTTAATGTTGTTTATATAGTGGGCATTAAAGACAGTCTTTAGACAGATTT CTACATGTGGAGGGGAGGTGGGGCTTTCCTGTAAGTTTGATCCTTTTTTTCCCCTTTAGTAGCAAACTAACATAACAGATTGGATTTATT TTACCTGACTACAGTTTTGGGGAAACCTGTCAAATAAATAATTGTTACATGCCTTTTTTTTTTAAATTTAAGCACATTGAAACTGCTTAA ATGGTCACATTTTTCAGCATTAGGATTAAGATACCATTTTTGTAGGCCTGGAAAACAAATAGCAAATGATTCAAAATTCATTGAATTGAC TTTGAAATGAAACTTTTCCCCCATAATTTGTTATATGGAAGATTTGCTACCCTGATCTTTTCCCTAGCATACTTCTAAAGTTGATTGAAT CCCTGAGTATCAATGAAGAAATCAGAGTTTAAGTGGCTAGGGAGAGCCAGGTATAAAGACTGATTAATAGAGTACTTCAGCTAATTAAAA ATTTAAATAGTAATAATTTATGAATGTGAATAAATTGGAAGGCAGCAAAAAGCATGATTATAGAATATTAAGTTCAATTATATATAGACA GTCCAGTTTCCTAGTGAATAGGTCAAGATTATTTGTTTTGTTTTGTGGCACTATCATAGTTCACTATAACTTCAAACTCCTGGGCTCAGG CTATCCTCCCACCTCAGCCTCTGAAGTAGCTGGGACTACTCACATGCGCCACCATGCCCAGCTAATGGTTTTTTTCTTTAGAGATGGGGG TCACTATACTGCCCAGGCTGGTCTTGAACTCCTAAGCTCAAGTGCTTCTCCCACATCAGCCTCCCAAAGTGCTGGGATTACAGCCATGAG CCACTGCATCTGGCCAAGATCAAGATTATGGATATTGGTATGTTAACTTTTAAAATAAAAGTACATGGGCTGGGCGCAGTGGCTAACGCC TGTAATCCCAGCAATTTGGGAGGCCGAGGCAGGCAGACCACCTGAGGTCAGGGGTTCGTGACCAGCCTGGCCAACATGGCGAAACCCCGT CTCTACTAAACATACAAAAATTAGCTGGGCATGGTGGCACATGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCACTTGA ACTCGGGAGGCGGAGGTTGCAGTGAGCCAAGATCGCGCCATTGCACTCCAGCCTGGGCAACAAGAGTGAAACTCCATCTCAGAAAATAAA AATAAAAATAAATAAAAGTACATGAAAAAAGTATATTCCCTTAAGCAGGTAAAATACTTGCATTGTATTTTTACATCATGAATTTGCTTG TTAAGAAATTTCTTTTCTGTAAGTGGTTAAAAGATAAACTGTATTCCATCCTCTGGGTTTTCAATTCTAAATTATTGGAGCTCAATGTAT GACATTTTACTGTAGTGTATTCCACTGAGAGGCAAGGAAATGGGAAAGTGTCAGGTAATTATAAATGGGAAAATTTTATTTTTATATGAT GTAAAGTTTTACAGTTTAAAATAGATCAGCATGTGATTTCTTGTAGAGATTAGCCATTTCATTTCTTTTTGCATTTTTGCCAGTTACATT AGTTTGCCCTATGATATACTATTCTGAGATACTTCAGCCCCGCACACATCAAGTACTAATTGTATACAGATAGTACAGATTTGTACTCTG ATTATAAGAATTTGTTACTACTAATTAAAAGCAAATTAATGTGGCTGGGCGTGGTAGCTCACACCTGTAATCCCAGCACTTTGGGTGGGC GGCTGAGGCGGGCGGATCACGAGGTCAGGAGTTGGAGACCAGCCTGCCCAATATGGTGAAACCCTGTCTCTACTAAAATTACAAAAATTA GCTGGGCTTGGCGGTACGTGCCTGTAATCCCAGCTACTGGGAAGGCCGAGGCAGGAGAATGGCTTGAACCCAGGAGGCGGAGGTTGCAGT GAGCCAAGATCACACCACTGCACTCCAGCCTGGGCGACAGAGCAAGACTCCGTCTCAAAAAAAAAAAAAGCAAAATATTTTTGCTGTGAT TGTATGTCCCCTTTTAAGGATATTTATTGCGCTTATAACCTTAATAGTTGTATTCATTACATTTCAACATGTCCAAGGTTAGCAGACATG TAGTTCCTGAAAACCAACATTTTAAAAGTTGCCTCTGGGCTGGGCATGGTGGCTCACGCCTGTAATCCCTGCACTTTGGGAGGCCGAGGT GGGCGGATCACGAGGTCAAGAGATGGAGACCATCCTGGCCAACATGCTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCTGGGTGT GGTGGCACACGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGAGGCGGAGGTTGCAGTGAGCCAAGA TTGCACCGCTGCACTCCAGCCTGGCAACAGAGCAAGACTCCATCTCAAAACAAACATACAAACAAAAAAAGGTGCCTCTGGTCCTGTGTT TTCTTTTTCCTTCTGAAAGTTCATAGAAACCTGGCATATAGAGCTTATTTTGCTGTTTTAACTGGTTGGCTCCACAAATCCTGCTACCTG ACATCAGTACAGCTTGACCGCAGTGAAGTACTTGATGGCTTGTTCATGTTTAGTTCACCTCTTTAGAAAGAAAGCTTTGTGGCCAGGTGC AGTGGCTCACACCTGTAATCCCAACACTTTGGGCAGCTGAGGTGAGCAGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACAT GGCAAAACCCTGTCTCTTCTAAAAATACAAAAATTAGCCGGGTGTGGTGGCGGAGGATGCAGTGAGCCAAGATCGTGCCACTGCACTCCA GCCTGGGCAACAGAGTGAGACTCTGTCTCAAAAAAAAAAAAAAATCGTTGTGCAGTAATAGATCATCCCAAAAAAGAATTGCCATGAACA GCGTTATGCGTAGAAAACAGATGGAAGTGTTGGTCATTAGAGCCTTGCTTTTTAAATTTTATTCTTTCCAAAAATTGGCGGTATGCTATC TATAATTTTATGTTTGATGTTGAAGAGGCAACACCAGAGACTAGAGAGGGAGATTACTCTGATATTTAGTGCCTAAAACTTTCATCTTGG CCGGGCACGGTGGCTCACACCTGTAATCCCAGCACTTCGGGAGGCCGAGGCAGGCTGATTACCTGAGGTCAGGAGTTCGAGACCAGCCTG GACAACATGGCAAAACCCGTCTCTACTAAAAATACAAAAATTAGCCAGGCATGGTGGTGGGCGCCTGTAATCCCAGCTACTCGGGAGGCT GAGGCGAGAGAATCGTTTGAACCCGGTAGGCGGAGGTTGCAGTGAGCCGAGATCATGCCACTGCACTCCAGCCTGGGCGACAAGAGTGAA ACTCCGTCTCAAAAAATAATAATAATTTTAAAAATAAAAGACAAAACTTTCATCTTTATTTCATGGCTTTATTTCATCTTTATTTCATTT TTGGTTGGGAAAACAAACAAAAATCTCTTAAGTTAGTCCTTTAATAGTCTTTTTAGAACCAAAGAAGGAAAGACTGCAAAAATGTTGCAT ACGTGACTCTTTATTGTCAGAATCTGTAGAAACTGGAGGTCTTTGTAAAGAAATAGACTAGTAGGATTGTGAGAATATATAGTGAGGGGG GATTTAGGATAAGGCTTCCTTGCTGGGATCCTTGGACAGAAACCTTACAATTGTTTAATATTTGCAGAGTAAAAGAGCAGCTATTGCTAT TTGAACCTACAGAAGAGACCTAAGACGAGCGTCTCTGTAATCTAAATTTATATGATAATGTTGTCCCAGACCCAAAGGCACACCTATTCT CAGTAACTTAGAGAAGTCTTGGAAGTTGCTTCTGAATTACAGTAAAGAAATTAAATGAAGTCTTTATCCTTAAATAGGGCCAGGCATTGC TATCAACATAGTGTCTTTGGTTTTCCCCTTTAAATAGAAAACACCAAGCAGGGCCTTTCCAGACAATGTAGTCTTTCCTGTAAAGAAAAT GGTTTTGGTGTGGGATTTGGTAAAAACACTGGTTAGTTTGTAATGAAGAAAGAATTTTGGCATAGACAGTCCGACCCAGTTCATGGATAC AGTTTGATCCCAGGGAGTTTAACAAAAGGAAGCTTTGGTTTTGCTAGCAACAGACTTGATCTTCTATAGTAATTAATTGCAATTAAGGTT TTCCAGGAGCTTTCTCATTTCTTAGCCCAGGGTCCAACCCCATTCCCTCTTTAAAAAAGAAAGAATAGGCCGGGAGCAGTGGCTCATGCC TGCAATCCCAGCACTTTGGGAGGCCAAGGCAGGTGGATCACAAGGTCAGGAGTTTGAGACCAGCGTGGCCAATATGGTGAAACCCTGTCT CTACTAAAAATACAAAATTAGCTAGGCGTGGTGGCAGGCGCCTGAGGCTGAGGCAGGAGAATCCTGCTAGTCTGAATTACAATAAGGAAA TTAAATGAAGGATTTATCTTTAATAGAGCCAGGCATTGCTATCAACATAACATGTTTGGTTTTCCCCTTTAAATAGAAAACACCAAGCAG GGCCTTTCCAGACAAGGTAGTCTGGAACCCAGGAGGCGGAGGTTGCAGTGAGCCGAGATCCCACCATTGCACTCCAGCCTGGGTGGCAGA GTGAGACTCCGTCTCAAAAAAAAAAAAAAGAAGGAATAGGAAAAGGACTTAGAGGCAGTTGATATAGAATTCTACTGGGGGTAAATGACA CTCTCAAAATACTTGGGAAAGAAGAATCACATGCCACAAGCTATAGCTTGATTAATATTTTAGCATGTTTTCCATGTTTGTATTCTAAAG TTTGTTTCCTTTGACATTCCATTATCTTACTTACTAGAGTGCCACCATTCTTATTTGTAATACAATCAGTGTTTTATGCCATTTGTGAAT CACACAATTGTTCTTTTTTCCCCATCACACACACTCACACACAAACACACACACTGTTAAAAATAAAAGAGGGGAAGGATAAAACAAAAA TAGATAGAATGATGATTATTACAATGTAACTTTAACATATATGAAGAGAAATTCTAACTCAGTTAAGTGAGAATTAAGATTGAAAGTATT AATGTTGCAAGTATTATCTCTAGCCATGGAATTTTTTGCTGGCTATAGAATGCTAATGTGAACAGAGTATATATCAGGAATATGATGTAT TATGGCACAGTGATAATATTATTGTTGATATTAGCCAGATGTGGTGGTTTGCACCTGTAGTCCGAACTTCTCAGGAGGATGAGGCAGGAG GATAGTTGAGCCCAGGAGTTTAAAGCAAGCCTGGGCAATACAGCAAGACCCCAATCTTTAAAATAAATAAATAAATAAGAATTATTCTTG AAAGTAATATTCTAACCTTCTGCCAACCAACAGAGATCCTCATATTCTTAAAGAAAATTAATATAGCTTATGGTTTTGATAAATTGGACT CTGATTTAAACTTTAAAATGTTATGACTTTTATTCTGATACATGGCTTCTAAAATATGTAAAAAATTATATTGAATGAATTAATACTTAA CCTGTTCATTTCTCTTAATTTATGTATTTATTCTGACTTTATTATACAGCTTATGTCTCACATCTGCCTTCTTGATATGTGCAAAATATT GTGTAAAAATAGTTTAAAACTCATCCCAGTTCCTAGTCAAGCGTGGGCTATAAGAGAGAAGGCTTAAGGTGTTCTTTAATGGAGGAACTT TTGAAAGATCACAAATGGAAAAAGCCTATTGAGAATTTATTGCCTTTGAGAGTAGAAAGGGCTCTAGAATATGAGCCAGAGACTTGGAAT TTAGTAATAGGTCTCCCACTGATTTGCTCCGTGTCCTTAGGCAATTCGTTTAATCTCTGTGTGCCTAGTTTCCCCTTGTAAATAAGAGTG GTAATACCTGTCCTCACCTACCTCACTAAATTGTTGGAGTTCTTTTGTTCTGAGTCAGGGTCTCACTCTGTTGCCCAGGCTGAACTACAG TAGTGTGATCATAGCTCACTACAGCCTCCAACTCCTGGGCCCAAACTATCCTCCTGCTTCAGCCTCCCAAGTAGCTGGGACTAGAGGTAC ATGCCACCACACCCAGCTAATTATTTTCTTTTATTGCAGAGATGGGGTCTCACATGTTGCCAAGGCTGATCTCTAACTCCTGAGCTCAAG CAGTCCTCCTGCCTCAGCCACCCAAAGTGCTGGGATTATAGGCATGATCACTAAATTGTTGTAAGAATAAGATAATGTTTGCGGAAGCAT TTGAGTTCTCCAAAGGAAAAGCTATTCAGACGTTCAAGATAATAGAAGAGTGTTGTGTGAAGGATTCCTTTCCAGTTTGCCTCTGTGAAA ATGTCTTTGTTGTAGATCATTTTATGAAATAGGAATAAGAGAAACATAGGCCTTATCATGGTGTAGTGTTCACTTACAAACATATCCTGT TGTTTCTTCCCTGCAAGATATCCAGCACACAGGCTGAATTTTTCTTTATAATAATCCTTGGCAAAAGCATAACTTTTCAAAAACCAAATG ATTTTAGTGGTGCTATGGCAGCTGCAGTTTTGAGTTAGATTAATGTGGTGAAAACCATCAAATACTTAGAAATTGACTGGGTGCGGTGGC TCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTAGGTGGATCACTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGCAAA ACCCCGTCTCTACTAAAGATACAAAAATTAGCTGGGCACGATGGAGGGTGCCTGTAATCCCAGCTACTCGGGAGGCTAAGGTGGGAGAAT TGCTTGGACCCAGGTGGCAGAGGTTGCAGTGAGCCAAGATTGTGCCACTGCACTCCAGCCTGGGCAACAAAGCGAAGCTCTGTCTCAATA AAAAAAAAAATAATAATAATAAAATACAAATACTTAGAAATTAACTTCGCCTTTGCCTTCAGGCACTTTTGCTACATGTTAGCATCAGAG GCTATTGTACAACTAGATGGTTATTCCCTGTTTCTTGGCCGATTTTTGGTACCTTTCTTTGAAGAAGAGGGTTAGATTTTAAGAAAGAAA GTGTGCTTATTTCACTCATGTCTTTGCAGAATTTAACTTTGCTTTACTTTAAAAATTCCAATCATCATGTACCTATAAAGGTTAAAATAT AGTGAAAGTTTCTGCTTCATGTGAATTCAATTCTGAGCACCTGCAGGTCATATCAGGTGTCTGATGCAGTTACCTTTATAGATCGTGGCA GGTCCTTACATTTCAACAGGCTTATGCATTTCCATGGGGGGAAGAGATTCTGTTTCTAGGAAATTACAAAGGGCACACCACTGCAGGGAG TGTAAACAATTCTTTGTTGCAACAGACAAGATTTTTTTTAAAAAAAGAAAAAAGGATGCATTTTAGGTACACAGGGTATGGACGCATTCA ACATTTACTTTTATCTCCACAGATGCCAACCTCCCCTTGTTGCAGGCAGTTGGGCTTTTCCAACTCATTGCTAACAAAGCTGGCATCTGC ATTAATTTCAATGAGAATTTCAAGTACTGAAGATGAAAAGTTGGGGAGATTCATGTTTGAAAAATGAAAAATGAACAAAAAATCCACCTT GTGCAGTGAGATAGCTAACGCTGATATATCAGGAATAATTTTAAACTATTTTTGCTGTAATGTGTAGCTTTAATGTCTCTTTTCAGTTAT GGACCCATAAAAGTATTCCTATATCTTGTGAATAAAGATCATTCTTGTGGACTAGTACGTGGATGCATTCATAGGCTTTGGGAAGCAGTG GTGTGCGTATGTGTGTCTATATCAATATTTTATGTTTATAACTCTGCGTATTAAGTTTATATAGAAAAAAATAATGTCTTTCTTTAGTGT TTGGGGGACTCAATGGTAATATGACCATTGCAGTGTAATCTGACTGCTCACTCTAGAGAACACTTCTGTTATACACAATGCACATACAAA CATACACCCCTAAAGCGTAGCTAACTGCTCCCACTAGATAATTGCTGCTAAAAACAAAACAAAACAAAACAATACAAAACAAAAAAAACC CTAAGTAATGGAGGAAGAAATAGCATTCTTTTAAAAGGGGCTTTTCTGAAGAGTAAAATGTAAATACAGGACATGTGGGGAGGGTGGGGC CGCCTGCAAAATGTCCTGAAGATGGACAAATAGCCTTTTAAATTCTACTTTTTAACCATCTTTACCGTGTGTGCCTATTTGTATTGCAGA TGTGAACTACTATTTTTGGAGGTTGATATCAGTATGTTTTGAAACTGAATTATTACATAAAATCAGAGTAACCTCTTTCTCCATCCTCCT TTTCCACACTATTCTTGCCAAATATTTCTACTGAAACCCAGTTTCAGCAAGGCAAAATGATGGGACTCTCAAACCTCCCTCCTCATCTTC CCTTCCCCTCTGTCTTATGCCTGGCCTGGCCTTTTTTGTTGTTGTTGGCTTTTCATAAGTAAGAAAAATTTATTGTAGTATTTCAAGACT GCAGAATTTCAAGTGTATATCTATAAATCTTTTTTTAAAATCTTCGGCTACACAGTAACATCAATTAAAACAGAAGAGTGAGTCTAAGTC TGTAATATGCTGTAGGACCAGATAAGATTTTGAATGAGACTAAACTTGACTGCCATATTTTAAGAGGAAATTGAAACTTTATGGTGGAGA ATGGATGAGAGCAAGTCTATGATATATATGTAGTCATTGTATAATTAGAAACACCAAATGCTGAATCCTATCACTGTGTTCTTGGGGGCC AGGCCTTGGATTTGGTTGTCATTTAAACTCCTTGAAGATTATATGTAATTATAATGAGCAGAAGGCAAATAAAGTTTTTGAACAAAAGTC CTTGTTTTCAGTATTTAAAATTTGGTAATATATTTTCTTTTTCAGTTAAACTATCTTCCCCACAAAAAATATTATACTTCAGTTAAACTA TCTTCCCCACAGAAATTATTATACTACGAACAAGTTATGAGTGAGACTGAGAAGCTTGAAGAAGCTGGTTTTTAAGCAGCTCATATAATA TTTTGTGTTAAAGAAAGTGTCATTGTTTCCTGTTGGGAGGCAAATAACAACAACAACAAAAGAAATTGTCATGATTCTTTCTGAGCCAAA CTGTCACGAAATGTTCTGTGACAGAACCACTACTCTTTTTTCTGCCATTCTGCCTACTGGAGAGTTCTATGTTGTATTTGTTTTTAATCC TTGATTTTAAAAATATTAATGGTTTTAGTGTTGCTTAGCTTCAGTTTGAAGTATAACTTTCACTAATAACTGCAATAAAAAGAAAAGCTT >6279_6279_5_ARHGEF2-AGO3_ARHGEF2_chr1_155927504_ENST00000313695_AGO3_chr1_36432556_ENST00000373191_length(amino acids)=1340AA_BP=544 MKEAKDARYTNGHLFTTISVSGMTMCYACNKSITAKEALICPTCNVTIHNRCKDTLANCTKVKQKQQKAALLKNNTALQSVSLRSKTTIR ERPSSAIYPSDSFRQSLLGSRRGRSSLSLAKSVSTTNIAGHFNDESPLGLRRILSQSTDSLNMRNRTLSVESLIDEEVIYSELMSDFEMD EKDFAADSWSLAVDSSFLQQHKKEVMKQQDVIYELIQTELHHVRTLKIMTRLFRTGMLEELHLEPGVVQGLFPCVDELSDIHTRFLSQLL ERRRQALCPGSTRNFVIHRLGDLLISQFSGPSAEQMCKTYSEFCSRHSKALKLYKELYARDKRFQQFIRKVTRPAVLKRHGVQECILLVT QRITKYPLLISRILQHSHGIEEERQDLTTALGLVKELLSNVDEGIYQLEKGARLQEIYNRMDPRAQTPVPGKGPFGREELLRRKLIHDGC LLWKTATGRFKDVLVLLMTDVLVFLQEKDQKYIFPTLDKPSVVSLQNLIVRDIANQEKGMFLISAAPPEMYEVHTASRDDRSTWIRVIQQ SVRTEVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLE LDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLD IHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQ VGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQ YGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLK NTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVT HPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIRE ACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADEL -------------------------------------------------------------- >6279_6279_6_ARHGEF2-AGO3_ARHGEF2_chr1_155927504_ENST00000313695_AGO3_chr1_36432556_ENST00000397828_length(transcript)=2611nt_BP=1743nt GGGATCCCGGGAGGGAGCGGAGCGGACCTGGGCTTGGTCGCCTCCAAGCCGGCGGGACCGAGTGCTTTAGGCCGCTTGAAAGAAAGTTGC TCCGACCCGGGAAAAGGAGAAGATGAAGGAAGCCAAGGATGCCCGCTATACCAATGGGCACCTCTTCACCACCATTTCAGTTTCAGGCAT GACCATGTGCTATGCCTGTAACAAGAGCATCACAGCCAAGGAAGCCCTCATCTGCCCAACCTGCAATGTGACTATCCACAACCGCTGTAA AGACACCCTCGCCAACTGTACCAAGGTCAAGCAGAAGCAACAGAAAGCGGCCCTGCTGAAGAACAACACCGCCTTGCAGTCCGTTTCTCT TCGAAGTAAGACAACCATCCGGGAGCGGCCAAGCTCGGCCATCTACCCCTCCGACAGCTTCCGGCAGTCCCTCCTGGGCTCCCGCCGTGG CCGCTCCTCCTTGTCTTTAGCCAAGAGTGTTTCTACCACCAACATTGCTGGACATTTCAATGATGAGTCTCCCCTGGGGCTGCGCCGGAT CCTCTCACAGTCCACAGACTCCCTCAACATGCGGAACCGAACCCTATCCGTGGAATCCCTCATTGACGAAGAGGTAATCTACAGTGAGCT GATGAGTGACTTTGAGATGGATGAGAAGGACTTTGCAGCTGACTCTTGGAGTCTTGCTGTGGACAGCAGCTTCCTGCAGCAGCATAAAAA GGAGGTGATGAAGCAGCAAGATGTCATCTATGAGCTAATCCAGACAGAGCTGCACCATGTGAGGACACTGAAGATCATGACCCGCCTCTT CCGCACGGGGATGCTGGAAGAGCTACACTTGGAGCCAGGAGTGGTCCAGGGCCTGTTCCCCTGCGTGGACGAGCTCAGTGACATCCATAC ACGCTTCCTCAGCCAGCTATTAGAACGCCGACGCCAGGCCCTGTGCCCTGGCAGCACCCGGAACTTTGTCATCCATCGCTTGGGTGATCT GCTCATCAGCCAGTTCTCAGGTCCTAGTGCGGAGCAGATGTGTAAGACCTACTCGGAGTTCTGCAGCCGCCACAGCAAGGCCTTAAAGCT CTATAAGGAGCTGTACGCCCGAGACAAACGCTTCCAGCAATTCATCCGGAAAGTGACCCGCCCCGCCGTGCTCAAGCGGCACGGGGTACA GGAGTGCATCCTGCTGGTGACTCAGCGCATCACCAAGTACCCGTTACTCATCAGCCGCATCCTGCAGCATTCCCACGGGATCGAGGAGGA GCGCCAGGACCTGACCACAGCACTGGGGCTAGTGAAGGAGCTGCTGTCCAATGTGGACGAGGGTATTTATCAGCTGGAGAAAGGGGCCCG TCTGCAGGAGATCTACAACCGCATGGACCCTCGGGCCCAAACCCCAGTGCCTGGCAAGGGCCCCTTTGGCCGAGAGGAACTTCTGAGGCG CAAACTCATCCACGATGGCTGCCTGCTCTGGAAGACAGCGACGGGGCGCTTCAAAGATGTGCTAGTGCTGCTGATGACAGATGTACTGGT GTTTCTCCAGGAAAAGGACCAGAAGTACATCTTTCCTACCCTGGACAAGCCTTCAGTGGTATCGCTGCAGAATCTAATCGTACGAGACAT TGCCAACCAGGAGAAAGGGATGTTTCTGATCAGCGCAGCCCCACCTGAGATGTACGAGGTGCACACAGCATCCCGGGATGACCGGAGCAC CTGGATCCGGGTCATTCAGCAGAGCGTGCGCACGGAGGTGGTTGACTCAATGGTTCAGCATTTTAAAGTAACTATATTTGGAGACCGTAG ACCAGTTTATGATGGAAAAAGAAGTCTTTACACCGCCAATCCACTTCCTGTGGCAACTACAGGGGTAGATTTAGACGTTACTTTACCTGG GGAAGGTGGAAAAGATCGACCTTTCAAGGTGTCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACG GACCTTGCCTGAGCCACTGGAATTAGACAAGCCAATCAGCACTAACCCTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCAT GAAATACACACCTGTGGGGCGTTCATTTTTCTCCGCTCCAGAAGGATATGACCACCCTCTGGGAGGGGGCAGGGAAGTGTGGTTTGGATT CCATCAGTCTGTTCGGCCTGCCATGTGGAAAATGATGCTTAATATCGATGAAAGAGACCTCTGGCAGCAGTGTGGAGAATAGATAGAGGA GAAAAAACTAATCTGAGAAGCCAGTTAGGAGGCTTTTCAATCACTAGTTCAGGTTTCAGTCTACATGTTACTTCCTTGAGAAGCAGTGTT TGACACCCTTCTCCCCCAATCCAGCCATCCCCCAAGTCTGAGTTAGGTATTTCTCTTCTGTATTCCCATAGCACAGTGTAATTCCCCTAT AATAGCATGTATCACCTTGAATTATGGGTGTTTATTGTTCTGTCTCTCCTGTTAGAACGAAAGCTCCATGAAGGGATTGTCATTTTATTC ACCAGTGTACCCTCTATGCCCAGCACAACTTTTGGTCATATTAAACAAAGAATGAATAAATAAATCCAAGAGCATAGGAGGAGGAGCATC >6279_6279_6_ARHGEF2-AGO3_ARHGEF2_chr1_155927504_ENST00000313695_AGO3_chr1_36432556_ENST00000397828_length(amino acids)=709AA_BP=544 MKEAKDARYTNGHLFTTISVSGMTMCYACNKSITAKEALICPTCNVTIHNRCKDTLANCTKVKQKQQKAALLKNNTALQSVSLRSKTTIR ERPSSAIYPSDSFRQSLLGSRRGRSSLSLAKSVSTTNIAGHFNDESPLGLRRILSQSTDSLNMRNRTLSVESLIDEEVIYSELMSDFEMD EKDFAADSWSLAVDSSFLQQHKKEVMKQQDVIYELIQTELHHVRTLKIMTRLFRTGMLEELHLEPGVVQGLFPCVDELSDIHTRFLSQLL ERRRQALCPGSTRNFVIHRLGDLLISQFSGPSAEQMCKTYSEFCSRHSKALKLYKELYARDKRFQQFIRKVTRPAVLKRHGVQECILLVT QRITKYPLLISRILQHSHGIEEERQDLTTALGLVKELLSNVDEGIYQLEKGARLQEIYNRMDPRAQTPVPGKGPFGREELLRRKLIHDGC LLWKTATGRFKDVLVLLMTDVLVFLQEKDQKYIFPTLDKPSVVSLQNLIVRDIANQEKGMFLISAAPPEMYEVHTASRDDRSTWIRVIQQ SVRTEVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEPLE -------------------------------------------------------------- >6279_6279_7_ARHGEF2-AGO3_ARHGEF2_chr1_155927504_ENST00000361247_AGO3_chr1_36432556_ENST00000324350_length(transcript)=3071nt_BP=1815nt GAGACCAACGCGTGCGGGCCGAACCCCTCCCCCCGCCTTCCCCCAACAATACAGGACGCCGGGGTCCGCGCCGCGTCCTCCCTGGTCCCC CCGTCCGATTATGTCTCGGATCGAATCCCTCACGCGGGCGCGGATCGACCGGAGCAGAGAGCTGGCGAGCAAGACCCGGGAAAAGGAGAA GATGAAGGAAGCCAAGGATGCCCGCTATACCAATGGGCACCTCTTCACCACCATTTCAGTTTCAGGCATGACCATGTGCTATGCCTGTAA CAAGAGCATCACAGCCAAGGAAGCCCTCATCTGCCCAACCTGCAATGTGACTATCCACAACCGCTGTAAAGACACCCTCGCCAACTGTAC CAAGGTCAAGCAGAAGCAACAGAAAGCGGCCCTGCTGAAGAACAACACCGCCTTGCAGTCCGTTTCTCTTCGAAGTAAGACAACCATCCG GGAGCGGCCAAGCTCGGCCATCTACCCCTCCGACAGCTTCCGGCAGTCCCTCCTGGGCTCCCGCCGTGGCCGCTCCTCCTTGTCTTTAGC CAAGAGTGTTTCTACCACCAACATTGCTGGACATTTCAATGATGAGTCTCCCCTGGGGCTGCGCCGGATCCTCTCACAGTCCACAGACTC CCTCAACATGCGGAACCGAACCCTATCCGTGGAATCCCTCATTGACGAAGCAGAGGTAATCTACAGTGAGCTGATGAGTGACTTTGAGAT GGATGAGAAGGACTTTGCAGCTGACTCTTGGAGTCTTGCTGTGGACAGCAGCTTCCTGCAGCAGCATAAAAAGGAGGTGATGAAGCAGCA AGATGTCATCTATGAGCTAATCCAGACAGAGCTGCACCATGTGAGGACACTGAAGATCATGACCCGCCTCTTCCGCACGGGGATGCTGGA AGAGCTACACTTGGAGCCAGGAGTGGTCCAGGGCCTGTTCCCCTGCGTGGACGAGCTCAGTGACATCCATACACGCTTCCTCAGCCAGCT ATTAGAACGCCGACGCCAGGCCCTGTGCCCTGGCAGCACCCGGAACTTTGTCATCCATCGCTTGGGTGATCTGCTCATCAGCCAGTTCTC AGGTCCTAGTGCGGAGCAGATGTGTAAGACCTACTCGGAGTTCTGCAGCCGCCACAGCAAGGCCTTAAAGCTCTATAAGGAGCTGTACGC CCGAGACAAACGCTTCCAGCAATTCATCCGGAAAGTGACCCGCCCCGCCGTGCTCAAGCGGCACGGGGTACAGGAGTGCATCCTGCTGGT GACTCAGCGCATCACCAAGTACCCGTTACTCATCAGCCGCATCCTGCAGCATTCCCACGGGATCGAGGAGGAGCGCCAGGACCTGACCAC AGCACTGGGGCTAGTGAAGGAGCTGCTGTCCAATGTGGACGAGGGTATTTATCAGCTGGAGAAAGGGGCCCGTCTGCAGGAGATCTACAA CCGCATGGACCCTCGGGCCCAAACCCCAGTGCCTGGCAAGGGCCCCTTTGGCCGAGAGGAACTTCTGAGGCGCAAACTCATCCACGATGG CTGCCTGCTCTGGAAGACAGCGACGGGGCGCTTCAAAGATGTGCTAGTGCTGCTGATGACAGATGTACTGGTGTTTCTCCAGGAAAAGGA CCAGAAGTACATCTTTCCTACCCTGGACAAGCCTTCAGTGGTATCGCTGCAGAATCTAATCGTACGAGACATTGCCAACCAGGAGAAAGG GATGTTTCTGATCAGCGCAGCCCCACCTGAGATGTACGAGGTGCACACAGCATCCCGGGATGACCGGAGCACCTGGATCCGGGTCATTCA GCAGAGCGTGCGCACGGAGGTGGTTGACTCAATGGTTCAGCATTTTAAAGTAACTATATTTGGAGACCGTAGACCAGTTTATGATGGAAA AAGAAGTCTTTACACCGCCAATCCACTTCCTGTGGCAACTACAGGGGTAGATTTAGACGTTACTTTACCTGGGGAAGGTGGAAAAGATCG ACCTTTCAAGGTGTCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACGGACCTTGCCTGAGCCACT GGAATTAGACAAGCCAATCAGCACTAACCCTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCATGAAATACACACCTGTGGG GCGTTCATTTTTCTCCGCTCCAGAAGGATATGACCACCCTCTGGGAGGGGGCAGGGAAGTGTGGTTTGGATTCCATCAGTCTGTTCGGCC TGCCATGTGGAAAATGATGCTTAATATCGATGAAAGAGACCTCTGGCAGCAGTGTGGAGAATAGATAGAGGAGAAAAAACTAATCTGAGA AGCCAGTTAGGAGGCTTTTCAATCACTAGTTCAGGTAAGAGATGGTGATGGTCTAATGTGGGATGGAGAGGAAGGATTAAGCTGAAAAAA TAGGTTTAAGAACCATGTCCAGAAAAAAAAAACTTTGGGTGTAGTACTGGTACATGGAACGGATTGGAAAAAAATAGACCAGAGCTTTAC TAGATTTTTGAAAGAATTGTTTTTGCAAATAAACTACAAGCCTGGCATATCAGTCAAGGTTCAGAACCTAGAGAAGCAGAACCAGTACGA AGTATAGAGAGAGAGTTTATGCAATTGTAGGGGCTAGCTAGGCAAGTCTGAAATTTTGGGGGCAGGCTGTCAGGAAGGGCAGGGAAATTC AGGCATGGGCTGAAGCAGTTATCTATAAGTGGAATTTCTTGCTCTCAGGGAAGCTTCAGCCCTACTTTTAAGACCTTTCACCTAATTGAA TCAGGCCCATCCACATTATTCAGGATAATCTCCATTACTTAAAGTCAACAGATTATGGATTTTAATTACATCTACAAAATACCTTCATAG CAACACCTAGATTAGTGTTTGATTAAACAAATGGCAGCTGGTAGCCTAGCAAGTTAACACATTAAAAACAACACCTGCCATGATGGCTTA CACTTGTAATCCCAGCACTTTGGGAGGCCAAAGTGGGAGGATCACTTGAGATTAGGAGTTTGCGATCAGGCTGAACAACATAGTGAGACC >6279_6279_7_ARHGEF2-AGO3_ARHGEF2_chr1_155927504_ENST00000361247_AGO3_chr1_36432556_ENST00000324350_length(amino acids)=737AA_BP=572 MSRIESLTRARIDRSRELASKTREKEKMKEAKDARYTNGHLFTTISVSGMTMCYACNKSITAKEALICPTCNVTIHNRCKDTLANCTKVK QKQQKAALLKNNTALQSVSLRSKTTIRERPSSAIYPSDSFRQSLLGSRRGRSSLSLAKSVSTTNIAGHFNDESPLGLRRILSQSTDSLNM RNRTLSVESLIDEAEVIYSELMSDFEMDEKDFAADSWSLAVDSSFLQQHKKEVMKQQDVIYELIQTELHHVRTLKIMTRLFRTGMLEELH LEPGVVQGLFPCVDELSDIHTRFLSQLLERRRQALCPGSTRNFVIHRLGDLLISQFSGPSAEQMCKTYSEFCSRHSKALKLYKELYARDK RFQQFIRKVTRPAVLKRHGVQECILLVTQRITKYPLLISRILQHSHGIEEERQDLTTALGLVKELLSNVDEGIYQLEKGARLQEIYNRMD PRAQTPVPGKGPFGREELLRRKLIHDGCLLWKTATGRFKDVLVLLMTDVLVFLQEKDQKYIFPTLDKPSVVSLQNLIVRDIANQEKGMFL ISAAPPEMYEVHTASRDDRSTWIRVIQQSVRTEVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFK VSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMW -------------------------------------------------------------- >6279_6279_8_ARHGEF2-AGO3_ARHGEF2_chr1_155927504_ENST00000361247_AGO3_chr1_36432556_ENST00000373191_length(transcript)=20962nt_BP=1815nt GAGACCAACGCGTGCGGGCCGAACCCCTCCCCCCGCCTTCCCCCAACAATACAGGACGCCGGGGTCCGCGCCGCGTCCTCCCTGGTCCCC CCGTCCGATTATGTCTCGGATCGAATCCCTCACGCGGGCGCGGATCGACCGGAGCAGAGAGCTGGCGAGCAAGACCCGGGAAAAGGAGAA GATGAAGGAAGCCAAGGATGCCCGCTATACCAATGGGCACCTCTTCACCACCATTTCAGTTTCAGGCATGACCATGTGCTATGCCTGTAA CAAGAGCATCACAGCCAAGGAAGCCCTCATCTGCCCAACCTGCAATGTGACTATCCACAACCGCTGTAAAGACACCCTCGCCAACTGTAC CAAGGTCAAGCAGAAGCAACAGAAAGCGGCCCTGCTGAAGAACAACACCGCCTTGCAGTCCGTTTCTCTTCGAAGTAAGACAACCATCCG GGAGCGGCCAAGCTCGGCCATCTACCCCTCCGACAGCTTCCGGCAGTCCCTCCTGGGCTCCCGCCGTGGCCGCTCCTCCTTGTCTTTAGC CAAGAGTGTTTCTACCACCAACATTGCTGGACATTTCAATGATGAGTCTCCCCTGGGGCTGCGCCGGATCCTCTCACAGTCCACAGACTC CCTCAACATGCGGAACCGAACCCTATCCGTGGAATCCCTCATTGACGAAGCAGAGGTAATCTACAGTGAGCTGATGAGTGACTTTGAGAT GGATGAGAAGGACTTTGCAGCTGACTCTTGGAGTCTTGCTGTGGACAGCAGCTTCCTGCAGCAGCATAAAAAGGAGGTGATGAAGCAGCA AGATGTCATCTATGAGCTAATCCAGACAGAGCTGCACCATGTGAGGACACTGAAGATCATGACCCGCCTCTTCCGCACGGGGATGCTGGA AGAGCTACACTTGGAGCCAGGAGTGGTCCAGGGCCTGTTCCCCTGCGTGGACGAGCTCAGTGACATCCATACACGCTTCCTCAGCCAGCT ATTAGAACGCCGACGCCAGGCCCTGTGCCCTGGCAGCACCCGGAACTTTGTCATCCATCGCTTGGGTGATCTGCTCATCAGCCAGTTCTC AGGTCCTAGTGCGGAGCAGATGTGTAAGACCTACTCGGAGTTCTGCAGCCGCCACAGCAAGGCCTTAAAGCTCTATAAGGAGCTGTACGC CCGAGACAAACGCTTCCAGCAATTCATCCGGAAAGTGACCCGCCCCGCCGTGCTCAAGCGGCACGGGGTACAGGAGTGCATCCTGCTGGT GACTCAGCGCATCACCAAGTACCCGTTACTCATCAGCCGCATCCTGCAGCATTCCCACGGGATCGAGGAGGAGCGCCAGGACCTGACCAC AGCACTGGGGCTAGTGAAGGAGCTGCTGTCCAATGTGGACGAGGGTATTTATCAGCTGGAGAAAGGGGCCCGTCTGCAGGAGATCTACAA CCGCATGGACCCTCGGGCCCAAACCCCAGTGCCTGGCAAGGGCCCCTTTGGCCGAGAGGAACTTCTGAGGCGCAAACTCATCCACGATGG CTGCCTGCTCTGGAAGACAGCGACGGGGCGCTTCAAAGATGTGCTAGTGCTGCTGATGACAGATGTACTGGTGTTTCTCCAGGAAAAGGA CCAGAAGTACATCTTTCCTACCCTGGACAAGCCTTCAGTGGTATCGCTGCAGAATCTAATCGTACGAGACATTGCCAACCAGGAGAAAGG GATGTTTCTGATCAGCGCAGCCCCACCTGAGATGTACGAGGTGCACACAGCATCCCGGGATGACCGGAGCACCTGGATCCGGGTCATTCA GCAGAGCGTGCGCACGGAGGTGGTTGACTCAATGGTTCAGCATTTTAAAGTAACTATATTTGGAGACCGTAGACCAGTTTATGATGGAAA AAGAAGTCTTTACACCGCCAATCCACTTCCTGTGGCAACTACAGGGGTAGATTTAGACGTTACTTTACCTGGGGAAGGTGGAAAAGATCG ACCTTTCAAGGTGTCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACGGACCTTGCCTGAGCCACT GGAATTAGACAAGCCAATCAGCACTAACCCTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCATGAAATACACACCTGTGGG GCGTTCATTTTTCTCCGCTCCAGAAGGATATGACCACCCTCTGGGAGGGGGCAGGGAAGTGTGGTTTGGATTCCATCAGTCTGTTCGGCC TGCCATGTGGAAAATGATGCTTAATATCGATGTTTCTGCCACTGCCTTCTACAAAGCACAACCTGTAATTCAGTTCATGTGTGAAGTTCT TGATATTCATAATATTGATGAGCAACCAAGACCTCTGACTGATTCTCATCGGGTAAAATTCACCAAAGAGATAAAAGGTTTGAAGGTTGA AGTGACTCATTGTGGAACAATGAGACGGAAATACCGTGTTTGTAATGTAACAAGGAGGCCTGCCAGTCATCAAACCTTTCCTTTACAGTT AGAAAACGGCCAAACTGTGGAGAGAACAGTAGCGCAGTATTTCAGAGAAAAGTATACTCTTCAGCTGAAGTACCCGCACCTTCCCTGTCT GCAAGTCGGGCAGGAACAGAAACACACCTACCTGCCACTAGAAGTCTGTAATATTGTGGCAGGGCAACGATGTATCAAGAAGCTAACAGA CAATCAGACTTCCACTATGATCAAGGCAACAGCAAGATCTGCACCAGATAGACAAGAGGAAATTAGCAGATTGGTAAGAAGTGCAAATTA TGAAACAGATCCATTTGTTCAGGAGTTTCAATTTAAAGTTCGGGATGAAATGGCTCATGTAACTGGACGCGTACTTCCAGCACCTATGCT CCAGTATGGAGGACGGAATCGGACAGTAGCAACACCGAGCCATGGAGTATGGGACATGCGAGGGAAACAATTCCACACAGGAGTTGAAAT CAAAATGTGGGCTATCGCTTGTTTTGCCACACAGAGGCAGTGCAGAGAAGAAATATTGAAGGGTTTCACAGACCAGCTGCGTAAGATTTC TAAGGATGCAGGGATGCCCATCCAGGGCCAGCCATGCTTCTGCAAATATGCACAGGGGGCAGACAGCGTAGAGCCCATGTTCCGGCATCT CAAGAACACATATTCTGGCCTACAGCTTATTATCGTCATCCTGCCGGGGAAGACACCAGTGTATGCGGAAGTGAAACGTGTAGGAGACAC ACTTTTGGGTATGGCTACACAATGTGTTCAAGTCAAGAATGTAATAAAAACATCTCCTCAAACTCTGTCAAACTTGTGCCTAAAGATAAA TGTTAAACTCGGAGGGATCAATAATATTCTTGTACCTCATCAAAGACCTTCTGTGTTCCAGCAACCAGTGATCTTTTTGGGAGCCGATGT CACTCATCCACCTGCTGGTGATGGAAAGAAGCCTTCTATTGCTGCTGTTGTAGGTAGTATGGATGCACACCCAAGCAGATACTGTGCCAC AGTAAGAGTTCAGAGACCCCGACAGGAGATCATCCAGGACTTGGCCTCCATGGTCCGGGAACTTCTTATTCAATTTTATAAGTCAACTCG GTTCAAGCCTACTCGTATCATCTTTTATCGGGATGGTGTTTCAGAGGGGCAGTTTAGGCAGGTATTATATTATGAACTACTAGCAATTCG AGAAGCCTGCATCAGTTTGGAGAAAGACTATCAACCTGGAATAACCTACATTGTAGTTCAGAAGAGACATCACACTCGATTATTTTGTGC TGATAGGACAGAAAGGGTTGGAAGAAGTGGCAATATCCCAGCTGGAACAACAGTTGATACAGACATTACACACCCATATGAGTTCGATTT TTACCTCTGTAGCCATGCTGGAATACAGGGTACCAGTCGTCCTTCACACTATCATGTTTTATGGGATGATAACTGCTTTACTGCAGATGA ACTTCAGCTGCTAACTTACCAGCTCTGCCACACTTACGTACGCTGTACACGATCTGTTTCTATACCTGCACCAGCGTATTATGCTCACCT GGTAGCATTTAGAGCCAGATATCATCTTGTGGACAAAGAACATGACAGTGCTGAAGGAAGTCACGTTTCAGGACAAAGCAATGGGCGAGA TCCACAAGCTCTTGCCAAGGCTGTACAGATTCACCAAGATACCTTACGCACAATGTACTTCGCTTAAATAGTCCAAGTATATTCTCTGAG AGGAAGTACTGAAAGATGAATTGACATACAACGTATGTTTCCAGTGAAGTCAATTGAGTAAGGACACCTCCAGCCATACAGAAACCAACA CTGTGTGGGGGCCAAGGTCTGATCCTTATGTTAATACAAGGAAGATTGTTTACTTCATCAAGGAACACAGCATCATTATGCAATATGAAA CCAGCCAACTGCTTTTTGTGCGGTCTCCTATAGGAAGTATCGCAATTGTTTTGTTTTCATTTCTTGTAGTCTAACCCTTTTAATGCCTTT ACCTCAAGTTGCTTGGCAGCACAACTATCTTTGCAAAAAAAAGTAAAGAAAAAGTAAATGATGGTTTAAAAAATACACACCTTCATGAAT AATCAAAGTGATTTTTCAGAATTATGTGTGCAAAAAATTAATGTGCATTCATATATTCTTGTAAAAGGTGTCTGTGTATTTTTAAAATAT ATACATCCATACTTCATATGCATATATATCTAGATCTGGATTGATAATAGATATATATGTGTCTGTTATATATTTTAGAGTTCATTCCAT TGGGGAATTTTCTTTCCCTTTTATTCTACCCCCACTACCGCCTTTATTTCTCTATTTCCCTTGCCTTCATCACCTACATTTTTTTCCCAG TCCTACCAGTGACATTCAAATGTTGATGTATCTGGTTCGTTTGAATATAAAATATGGCAAACTAGAATTCTACTTTTATTTTGCATACCC TACTCCTGACTCCTATCTCATACACAATTCTGAGTTCTCAACTCTTGATATTGCTGTCTTAAGAAACAAAATTTTATATATATATGTATA CATACATACACAGACACAGACACACACATATATATACATAAAATAACTTTCTGTGAGAGTGCGTCTCTCCCCTCCCACTCAGAACATACA TTTACCATTTGCGCAATTTGTATATAAGCAGTAGCAACCTGAACTATTCTTTTTCTTTTTTCTTTTTCTTTTCTTTCTTTTTTTTTTTTA ATGAGACAGAGCCTCGCTCTGTCACCAGGCTGGAGTGCAGTGGCGAGATCTCGGCTCACTGCAACTTCCGCCTCTCGGGTTCAAGCAATT CTCCTGCCTCAGCCTCCCGAGTAGCTGGGTTTACAGGCATGTGCCACCACACCCAGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTC ACCGTGTTGGCCAGGATGGTCTCGATCTCTTGACCTTGTGATCCACCCGCCTCGACCTCCCAAAGTGCTGGGATTACAGGCATGAGCCAC CGCACCCGGCCTACTATTCTTTTTCTTTAGTGAGTTTGTTAAAGCTGCTATAAATATAAAACCTGTCAGAAGTTGTAACTTTCTCTCTGG TAAGTGATGTGTATTCTGAAGCCTTCTGTTTCTATGGGTTATACATGGAAATTCTTTAAAGGTTTTATAAAGGGTAAATATTTTAAAAGA TTAGAGCTCTGTAGGGTTGAGACCTCTGAAATTGAGTAGAGAGAAGAGTTTGTTGAGGGATTTTTTTGTTTTGTTTTTTGATAGTTTACT TGCTGCCTCTCATACCTTAATGTGATTTTCATATATTTTTTATATATATATATGTATGTGTGTGTATATAAACACATATGTATGTGTTTG GAAGTATAGCTTCCTTTTCTTTTATATTTATTAGAATAGTGCTTTAATAATTATAGAATTGTATTGGCAGCATCTTTTATAGAAATATAA TCATGTTTATTTTAAGAACTGACAACTTGTTTTTGCTATCTTTTAGTGCAATAAGCAGTTTTAAAGGAAAGTTGTGTCTGCATCTTTACC ATGGATAGTAGGAGGAACAGGCACCTCCATAGTTTAAAAGGGCAAAGAATACAGCCTTAATTTCAGAAGGAAAGTTTTGTAATTTTCAGT TTTAAAGCATATCTTTTAAAATTCATCATGATAAAAGGCTGGACGCGGTGGCTCATGCCTGTAATCCTAGCACTTTGGGAGGCTGAGACA GGTATATCACCGGAGCTCAGGAGTTTGAGACCAGCCTGGCCAACGTGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCTGGGCG TGGTAGTGGGCACCTCTAATCCCAGCTACTCGGGAGGCTGAGGCAGGATTGCTTGAACCTAGGAGGCGGAAGTTACAGTGAGCCAAGACT GCACCATTGCACTCCAGCCTGGGCAACAAAACCAAAACTCCGTCTCAAAAGAAAAAAAAATCATAATGAAAATGAAGTGAAATTGCCTAA ATGAGTCCAACTTGAATATTAGAAATAAAGTTGAACTTTTATATAATTGTGAATAGCTTAACATATTTAAATTATTTGCAAATAGATTGT GTTTATTGAAGAATCATATTGGCTAGATGCCCATTTTCATTTACTAAAATGAATCAGGAAAATGCAAGATGATATTTTAAAACTTTTGCT AATGTATCACCAGTATAACTTTCCTTTTAAAATTAAGGTGATAGTAACAAAGGAAGTTAGGACTTTGATCATTTTAAATCAGTTAAATCA CTGAAACGTGGGAAATTGTTTTACAAAACTTTTATTGATTACACTTTAAGGTATTAAAAAGTACTATAAAGCTATCAAAACTGAGTTTAT CAGTAACATTGGATTCAGGGGAGCTTTGCACTTTGTAACTCATGAAAATTGCATTTTGATTTTTTTTTTTTTTGCACTGGTTCAGAGTAT AGATACTACAGATTGTTTCCAGTGGGCATTGTTGTTAGCCTTTCAGAATTCCATCTGCACGTGAAACCTAATGGATTTAGATCTTTAGTT TCTCTCTTACCTGTAATCCACTATTATTGCCAATTCACTGTATTTTGAGCCTAAAATCTGAGCCCATGTCCTCTGACAGGCATGAAATCT TTTGTCCCTCTGCCAGAAAACTAAGAAAGTACTGTATTTTGTATGTTTATTATTTTGAAGTGTCTGAAATGCAATTTACAACACTGTTGC AAAGAACTTTACAAAAGGTAATATTTGTATCGTATATACATTTTTTCTCCCAGCCTTCTCCCATCTCCTCCAGAAAAATTTCCTATAAAG ATGGATTTTTTTACACTGAAATTTTACTGAATATAGTCAGGATCATGGGCAAGAGAAGAAAATAGTATACCCAAGATGATAAAAATTTAA TTCGTCTATGCTTGATCAGTGTGAGTAAAACATCTTCCTTTATCATGGGAGCTGCACAGATTCATGTGGGAAACTTTAGGGAATGACTGT AGATACCCTTTCTCTATGTACTCTCTCACCTAATTTTCAGTCACTCATATATGCTAGAGTGGAGCCCTTAATTTAAATCTATTTGGAAGG ACTTTTTTAAGAGGAAAAATATTTTTTCTAAATTATAAAGCTTTACCTTTTGAGTGATTTCTTTTTTAGAGTGCTCTTACACTAGTCAGC ATTGCTAGTTTAAAGTTGATTAACTTGAAAGAGTATGTATACTATATTTCTATTTTGCTAACAAATTGGTATATTAATTACCATTGGTTC TTAATTACAAGAAAACTTGTGCTTAGAATTTTAAGATAAAAGGCTAAGTGACAAATGCTTCTTGAAATTTGTCCTATTTATTGTTGCATT TCTGGTGTAGAATTTCTAATCTTTTTTATTTTAAAAAAGTTTTTTTTTTTAAGTTAAACATGAAATTCACAGTGACCCTTCTGCTCCTGC CCTTGCTCACTAACTATATCATGAATGCTAGATTTTGGTCTTCTTTTTTCTGTGATGTATCTTACGAGACTGACTGTAAAATATCAGTCT GGCAACTAGATAATTGATTTTCATATGAAGAAGAGTTGGGAGTTTAATGTATATTCTTGATGGTTAATGTGTCTACATAAAGTGCTGATA CATGTATTATATCACAGTATCAGGTTACTGGCATGGAGGACCATACACTTACAATATTGTAGCTGCTATATTTATTTAAGTAGATTCTGA CAGTTACTGCACTAAACAGTAAGGAGATAAGCAGGATTCAAGGCTAGTGTTAGACCCTTTTTTTTCCTAAGAGTAAGGACACGGAATATC AAAGTAACAAAGGGTGCTGCCATTTTAGTTTCAATTTAATATCAGGATATTCTTTGTTTTAGAAATGTAGATTTTGACTTTTACAGTTTG AAAAAGGGTACCTCAGCCTCTTCAGTACTGGTTTTTTGGCACATTTCAACAGAAATATTAGATTCCCTTTCTTTTTCTTAATAGTGATCT TCTAACAAGTTTCTTGGAAAAACTATCATTCTAAGGGAAATCCCTGTTTATAACCTATTAATATATTTCTATTCCTAGAAGAGAGTCTAG CAGGGATTCTAGTAGGAATTACTGAGTGTTTTGGAAGGCACTTGATAGAGGCATCTCTGCTTTCCAGCACAGGGATTCTCAGCCTTCTAA AGATCTAGACCAGTTTCCAAGCTAGCTTCTCCACAGCCCACCACTGCCTAGTGTTTGCTTGTGTATTCTCTAATGGATTTTAGGAGGATA GGCCTTCTGACAGAGTCATGAAAGACTGAAGGCATGTCTAGGGAAATAAAACCTGACTTGCCCTTCAGCAGGAATGACTGGCAGCGGATC TCTGTGTTCAAGGAAAGGGTGAGCGCTAAGCATGCCAGTGATGGATCCGAAGTATTTAGATGGATTGCAGACCAGGAATTAGAGACCGTT TGTGACTCAAGGAACTTGATGGATCTGTTTAGAGCCCTACATGAATTTGCCAAGGGCAGTGATTTTTATGAAATTCAAGAAGCAAACGAC TTCGATACAGCTAGAATATGTTGCAGTCTTCCTATTTCAAACTTGATTTTAATATTTTTACCAAGAAGTTTAACTGACAACTCTGCAAAA TTTTCATTCAGTATCATTAAACCTGAGTTAAATGTTTGCTTAGCTTATCCTCTTAGATGTTCTTCTGTTGAACAGGCAGGTTGCCCTTAA CAGTAACTTGCTACTTAAATTACCTTTTATTAGTTAGTCAAGCTGCAAAAATATCATTAGTGTGGCGTCTTTATTTTGGCTTTATCCATA TGAAGTATTCATTATTTTCATTCTTTTTGAGAATTCATAAATGTCTTAAAGCTTCAGTAAGAATTGTTGGGAGGTTTGACATCAAGTAAC GCCTTCCTGTGTAGCAGTATAACCCTAATTTAGAACTCTTGTTTTCCTATTTCAGTCCTCATATTTGATCATAGAAAAGCACTTTTGTGA TTCTATAGGAGTCAAAAAATCAGCCAAGAGTAGGTAAGTCAGTCAGCACAGAAATCAGAAAGTGAGAATTTTCTCCAAAAAATCTTTTTA AAAAAGTCCTGCTTATACTAAGAACATTCTTGATCCGTTGCAGTGTTAGAAATGACACTGTGATTAGTGAAAGCCAAGCTGAGTCCCAGG AAGCAGGGAGGGGGAGTGTGTGTGTGTGTATATGTATGAGTGTGTATATATATAATCTCACACACACACACAAAGGGAAAAATTATTTTG ACTTTTTTCCTACTTTTAAAATGGTACATTTAAGTTTATAATTTTCCATGTCAGTCAACATAATTTTTTAAACTAAGGTATAATGGTCAA GGCTTGTGCTAATATTACCTACTACTCATTGAAATTTATATTACTTTACCCATCAAAACTAGTACTCCAGATGTTTACATCATTGATTAA ATCTCAAGAATCTTTTGTTCTTAAAATATGGAAGTTAAAGATTTTAATTTGAATTAAAGATAGAAGGATGGTAAATTCAATATAGAGGGT TGAGATTTACCAGTGAGAAACCCTGTTGAAGTATCAGGTAAATGGTGTGACAAAATTAGAATCCTGTCAAATCACCTATCCAGCCATCGG GGTCCCTTCCTTTTTTAGACTAATTTCTAAGGTAACCAGAATCTAATGTATCTATGTTAGGGTCTCAGTAAAGCAAAGACGTTTGTCAGG GCGTAGACTCTTGAGTTAAATTTTTTAATCATTTTTTAAAGCAAGGCGGTTCTTAGAAAGTGCCTTTTCAGAAGATGGTGCTGTAGATTT TTATTTTTCAAGTAGCACGAAGCTAAGAATTTTAAAGATAAATTATTTTAGAACTCCAAGAGTGTGACAGTTTCATAAAAATAATGTTAG TTGTTGTCTTGAATCTCGTCCAAGGGAACCAAGGAAAGCTTTTATGCAGTAAAGTATCTAGGTAAATGCTCACCAAATTTATTTTGTAAA TTTGAAAACAAAATATTTAGTAGAATTACCTCTTTTAATTCCCAACTGTGTTGGAGGAAATCCATAATGCACATAAAACAGCAAACCTAC TTAACTTTTTAACAAGATTATGGGTATAGTACCAATGTCCAAAGGGAAATGTAACTTGCCTGGAATCATAGGCAACATTTTCTAATTAAT CTTTTTTTTTTTTTTTTTTTTTGAGACAAAGTCTTGCTCTGTCACCTAGGCTGGAGTGCAGTGGCTCAATCTCAGCTTACTGCAAACTCC GCCTCCCGGGTTCAAGTGATTCTCGTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCATGCACCACCACACCCGGCCCTAATTAGTCA TTATTAAGGAGGACTGCTCATAAAGGCAGTACCAAATCATCATTCAGATCAGCTTAAGTGAGAAAGCAAAATGATAATCTCTATTGTTAG AGAAATTTTCTTTTCTAGACACCAAGGAATATTTTAAATGATTTTTTATTTTTTCTAGGATGCAGGAACTATGAAAAATGATGACAAGGC ATTTAAAAGGGTATGATCAGTTAAATAGAAGTAGGGTCTGCAAATTGTGCTTAAGGGGAAATAAGCAAAAGAAAGGAAAATAGTAGAACC TTTCATACTAATTAGAAATGTAGTTACCTACCAGAGGGCAATTTTGCTCCATACCAGGAAGCAGTAAATAGCAGTAAATGATCACCTAGG CACTTCTTTCCTGTGAATTTGGTGAGCATTCTTCCAGAAAAGAAGACTAAAAGCAAACAACAACAACAACAAAAAATACCACACCTCAGT AACCTTGTATGCTGCATTATATAATAATGATAGTAAAATTATATTGTTTGGAGTGTACTGTGTCTGTTTGCAAATATACATGCACATTAA ACTTTTTTGTTTTTATAATGTCTTAATAGCAATTATGAGTTTATTTTTGTTAAGATTAATTTTTCTATTGTGATGTTTATATTTATTGGC AATTTGTATGCAACTTTTATATTTTGCTTGTCGGTTTTAAGGTATTTTATTTTTATAGATATTTCTAGCTTTCCTCATTCTTTGTAATAG CAGCAAAGATTAAGATGGAGTGTTAATATACCAACCAAACTACGAATTCCATAAACTCTAGAGTTTGGATTTTTACCAATAAACCATTAA CACTATTTTGTAACTTAGAATATTTAATGTTGTTTATATAGTGGGCATTAAAGACAGTCTTTAGACAGATTTCTACATGTGGAGGGGAGG TGGGGCTTTCCTGTAAGTTTGATCCTTTTTTTCCCCTTTAGTAGCAAACTAACATAACAGATTGGATTTATTTTACCTGACTACAGTTTT GGGGAAACCTGTCAAATAAATAATTGTTACATGCCTTTTTTTTTTAAATTTAAGCACATTGAAACTGCTTAAATGGTCACATTTTTCAGC ATTAGGATTAAGATACCATTTTTGTAGGCCTGGAAAACAAATAGCAAATGATTCAAAATTCATTGAATTGACTTTGAAATGAAACTTTTC CCCCATAATTTGTTATATGGAAGATTTGCTACCCTGATCTTTTCCCTAGCATACTTCTAAAGTTGATTGAATCCCTGAGTATCAATGAAG AAATCAGAGTTTAAGTGGCTAGGGAGAGCCAGGTATAAAGACTGATTAATAGAGTACTTCAGCTAATTAAAAATTTAAATAGTAATAATT TATGAATGTGAATAAATTGGAAGGCAGCAAAAAGCATGATTATAGAATATTAAGTTCAATTATATATAGACAGTCCAGTTTCCTAGTGAA TAGGTCAAGATTATTTGTTTTGTTTTGTGGCACTATCATAGTTCACTATAACTTCAAACTCCTGGGCTCAGGCTATCCTCCCACCTCAGC CTCTGAAGTAGCTGGGACTACTCACATGCGCCACCATGCCCAGCTAATGGTTTTTTTCTTTAGAGATGGGGGTCACTATACTGCCCAGGC TGGTCTTGAACTCCTAAGCTCAAGTGCTTCTCCCACATCAGCCTCCCAAAGTGCTGGGATTACAGCCATGAGCCACTGCATCTGGCCAAG ATCAAGATTATGGATATTGGTATGTTAACTTTTAAAATAAAAGTACATGGGCTGGGCGCAGTGGCTAACGCCTGTAATCCCAGCAATTTG GGAGGCCGAGGCAGGCAGACCACCTGAGGTCAGGGGTTCGTGACCAGCCTGGCCAACATGGCGAAACCCCGTCTCTACTAAACATACAAA AATTAGCTGGGCATGGTGGCACATGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCACTTGAACTCGGGAGGCGGAGGTT GCAGTGAGCCAAGATCGCGCCATTGCACTCCAGCCTGGGCAACAAGAGTGAAACTCCATCTCAGAAAATAAAAATAAAAATAAATAAAAG TACATGAAAAAAGTATATTCCCTTAAGCAGGTAAAATACTTGCATTGTATTTTTACATCATGAATTTGCTTGTTAAGAAATTTCTTTTCT GTAAGTGGTTAAAAGATAAACTGTATTCCATCCTCTGGGTTTTCAATTCTAAATTATTGGAGCTCAATGTATGACATTTTACTGTAGTGT ATTCCACTGAGAGGCAAGGAAATGGGAAAGTGTCAGGTAATTATAAATGGGAAAATTTTATTTTTATATGATGTAAAGTTTTACAGTTTA AAATAGATCAGCATGTGATTTCTTGTAGAGATTAGCCATTTCATTTCTTTTTGCATTTTTGCCAGTTACATTAGTTTGCCCTATGATATA CTATTCTGAGATACTTCAGCCCCGCACACATCAAGTACTAATTGTATACAGATAGTACAGATTTGTACTCTGATTATAAGAATTTGTTAC TACTAATTAAAAGCAAATTAATGTGGCTGGGCGTGGTAGCTCACACCTGTAATCCCAGCACTTTGGGTGGGCGGCTGAGGCGGGCGGATC ACGAGGTCAGGAGTTGGAGACCAGCCTGCCCAATATGGTGAAACCCTGTCTCTACTAAAATTACAAAAATTAGCTGGGCTTGGCGGTACG TGCCTGTAATCCCAGCTACTGGGAAGGCCGAGGCAGGAGAATGGCTTGAACCCAGGAGGCGGAGGTTGCAGTGAGCCAAGATCACACCAC TGCACTCCAGCCTGGGCGACAGAGCAAGACTCCGTCTCAAAAAAAAAAAAAGCAAAATATTTTTGCTGTGATTGTATGTCCCCTTTTAAG GATATTTATTGCGCTTATAACCTTAATAGTTGTATTCATTACATTTCAACATGTCCAAGGTTAGCAGACATGTAGTTCCTGAAAACCAAC ATTTTAAAAGTTGCCTCTGGGCTGGGCATGGTGGCTCACGCCTGTAATCCCTGCACTTTGGGAGGCCGAGGTGGGCGGATCACGAGGTCA AGAGATGGAGACCATCCTGGCCAACATGCTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCTGGGTGTGGTGGCACACGCCTGTAG TCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGAGGCGGAGGTTGCAGTGAGCCAAGATTGCACCGCTGCACTCCA GCCTGGCAACAGAGCAAGACTCCATCTCAAAACAAACATACAAACAAAAAAAGGTGCCTCTGGTCCTGTGTTTTCTTTTTCCTTCTGAAA GTTCATAGAAACCTGGCATATAGAGCTTATTTTGCTGTTTTAACTGGTTGGCTCCACAAATCCTGCTACCTGACATCAGTACAGCTTGAC CGCAGTGAAGTACTTGATGGCTTGTTCATGTTTAGTTCACCTCTTTAGAAAGAAAGCTTTGTGGCCAGGTGCAGTGGCTCACACCTGTAA TCCCAACACTTTGGGCAGCTGAGGTGAGCAGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGCAAAACCCTGTCTCTT CTAAAAATACAAAAATTAGCCGGGTGTGGTGGCGGAGGATGCAGTGAGCCAAGATCGTGCCACTGCACTCCAGCCTGGGCAACAGAGTGA GACTCTGTCTCAAAAAAAAAAAAAAATCGTTGTGCAGTAATAGATCATCCCAAAAAAGAATTGCCATGAACAGCGTTATGCGTAGAAAAC AGATGGAAGTGTTGGTCATTAGAGCCTTGCTTTTTAAATTTTATTCTTTCCAAAAATTGGCGGTATGCTATCTATAATTTTATGTTTGAT GTTGAAGAGGCAACACCAGAGACTAGAGAGGGAGATTACTCTGATATTTAGTGCCTAAAACTTTCATCTTGGCCGGGCACGGTGGCTCAC ACCTGTAATCCCAGCACTTCGGGAGGCCGAGGCAGGCTGATTACCTGAGGTCAGGAGTTCGAGACCAGCCTGGACAACATGGCAAAACCC GTCTCTACTAAAAATACAAAAATTAGCCAGGCATGGTGGTGGGCGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCGAGAGAATCGTTT GAACCCGGTAGGCGGAGGTTGCAGTGAGCCGAGATCATGCCACTGCACTCCAGCCTGGGCGACAAGAGTGAAACTCCGTCTCAAAAAATA ATAATAATTTTAAAAATAAAAGACAAAACTTTCATCTTTATTTCATGGCTTTATTTCATCTTTATTTCATTTTTGGTTGGGAAAACAAAC AAAAATCTCTTAAGTTAGTCCTTTAATAGTCTTTTTAGAACCAAAGAAGGAAAGACTGCAAAAATGTTGCATACGTGACTCTTTATTGTC AGAATCTGTAGAAACTGGAGGTCTTTGTAAAGAAATAGACTAGTAGGATTGTGAGAATATATAGTGAGGGGGGATTTAGGATAAGGCTTC CTTGCTGGGATCCTTGGACAGAAACCTTACAATTGTTTAATATTTGCAGAGTAAAAGAGCAGCTATTGCTATTTGAACCTACAGAAGAGA CCTAAGACGAGCGTCTCTGTAATCTAAATTTATATGATAATGTTGTCCCAGACCCAAAGGCACACCTATTCTCAGTAACTTAGAGAAGTC TTGGAAGTTGCTTCTGAATTACAGTAAAGAAATTAAATGAAGTCTTTATCCTTAAATAGGGCCAGGCATTGCTATCAACATAGTGTCTTT GGTTTTCCCCTTTAAATAGAAAACACCAAGCAGGGCCTTTCCAGACAATGTAGTCTTTCCTGTAAAGAAAATGGTTTTGGTGTGGGATTT GGTAAAAACACTGGTTAGTTTGTAATGAAGAAAGAATTTTGGCATAGACAGTCCGACCCAGTTCATGGATACAGTTTGATCCCAGGGAGT TTAACAAAAGGAAGCTTTGGTTTTGCTAGCAACAGACTTGATCTTCTATAGTAATTAATTGCAATTAAGGTTTTCCAGGAGCTTTCTCAT TTCTTAGCCCAGGGTCCAACCCCATTCCCTCTTTAAAAAAGAAAGAATAGGCCGGGAGCAGTGGCTCATGCCTGCAATCCCAGCACTTTG GGAGGCCAAGGCAGGTGGATCACAAGGTCAGGAGTTTGAGACCAGCGTGGCCAATATGGTGAAACCCTGTCTCTACTAAAAATACAAAAT TAGCTAGGCGTGGTGGCAGGCGCCTGAGGCTGAGGCAGGAGAATCCTGCTAGTCTGAATTACAATAAGGAAATTAAATGAAGGATTTATC TTTAATAGAGCCAGGCATTGCTATCAACATAACATGTTTGGTTTTCCCCTTTAAATAGAAAACACCAAGCAGGGCCTTTCCAGACAAGGT AGTCTGGAACCCAGGAGGCGGAGGTTGCAGTGAGCCGAGATCCCACCATTGCACTCCAGCCTGGGTGGCAGAGTGAGACTCCGTCTCAAA AAAAAAAAAAAGAAGGAATAGGAAAAGGACTTAGAGGCAGTTGATATAGAATTCTACTGGGGGTAAATGACACTCTCAAAATACTTGGGA AAGAAGAATCACATGCCACAAGCTATAGCTTGATTAATATTTTAGCATGTTTTCCATGTTTGTATTCTAAAGTTTGTTTCCTTTGACATT CCATTATCTTACTTACTAGAGTGCCACCATTCTTATTTGTAATACAATCAGTGTTTTATGCCATTTGTGAATCACACAATTGTTCTTTTT TCCCCATCACACACACTCACACACAAACACACACACTGTTAAAAATAAAAGAGGGGAAGGATAAAACAAAAATAGATAGAATGATGATTA TTACAATGTAACTTTAACATATATGAAGAGAAATTCTAACTCAGTTAAGTGAGAATTAAGATTGAAAGTATTAATGTTGCAAGTATTATC TCTAGCCATGGAATTTTTTGCTGGCTATAGAATGCTAATGTGAACAGAGTATATATCAGGAATATGATGTATTATGGCACAGTGATAATA TTATTGTTGATATTAGCCAGATGTGGTGGTTTGCACCTGTAGTCCGAACTTCTCAGGAGGATGAGGCAGGAGGATAGTTGAGCCCAGGAG TTTAAAGCAAGCCTGGGCAATACAGCAAGACCCCAATCTTTAAAATAAATAAATAAATAAGAATTATTCTTGAAAGTAATATTCTAACCT TCTGCCAACCAACAGAGATCCTCATATTCTTAAAGAAAATTAATATAGCTTATGGTTTTGATAAATTGGACTCTGATTTAAACTTTAAAA TGTTATGACTTTTATTCTGATACATGGCTTCTAAAATATGTAAAAAATTATATTGAATGAATTAATACTTAACCTGTTCATTTCTCTTAA TTTATGTATTTATTCTGACTTTATTATACAGCTTATGTCTCACATCTGCCTTCTTGATATGTGCAAAATATTGTGTAAAAATAGTTTAAA ACTCATCCCAGTTCCTAGTCAAGCGTGGGCTATAAGAGAGAAGGCTTAAGGTGTTCTTTAATGGAGGAACTTTTGAAAGATCACAAATGG AAAAAGCCTATTGAGAATTTATTGCCTTTGAGAGTAGAAAGGGCTCTAGAATATGAGCCAGAGACTTGGAATTTAGTAATAGGTCTCCCA CTGATTTGCTCCGTGTCCTTAGGCAATTCGTTTAATCTCTGTGTGCCTAGTTTCCCCTTGTAAATAAGAGTGGTAATACCTGTCCTCACC TACCTCACTAAATTGTTGGAGTTCTTTTGTTCTGAGTCAGGGTCTCACTCTGTTGCCCAGGCTGAACTACAGTAGTGTGATCATAGCTCA CTACAGCCTCCAACTCCTGGGCCCAAACTATCCTCCTGCTTCAGCCTCCCAAGTAGCTGGGACTAGAGGTACATGCCACCACACCCAGCT AATTATTTTCTTTTATTGCAGAGATGGGGTCTCACATGTTGCCAAGGCTGATCTCTAACTCCTGAGCTCAAGCAGTCCTCCTGCCTCAGC CACCCAAAGTGCTGGGATTATAGGCATGATCACTAAATTGTTGTAAGAATAAGATAATGTTTGCGGAAGCATTTGAGTTCTCCAAAGGAA AAGCTATTCAGACGTTCAAGATAATAGAAGAGTGTTGTGTGAAGGATTCCTTTCCAGTTTGCCTCTGTGAAAATGTCTTTGTTGTAGATC ATTTTATGAAATAGGAATAAGAGAAACATAGGCCTTATCATGGTGTAGTGTTCACTTACAAACATATCCTGTTGTTTCTTCCCTGCAAGA TATCCAGCACACAGGCTGAATTTTTCTTTATAATAATCCTTGGCAAAAGCATAACTTTTCAAAAACCAAATGATTTTAGTGGTGCTATGG CAGCTGCAGTTTTGAGTTAGATTAATGTGGTGAAAACCATCAAATACTTAGAAATTGACTGGGTGCGGTGGCTCATGCCTGTAATCCCAG CACTTTGGGAGGCCGAGGTAGGTGGATCACTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGCAAAACCCCGTCTCTACTAAAG ATACAAAAATTAGCTGGGCACGATGGAGGGTGCCTGTAATCCCAGCTACTCGGGAGGCTAAGGTGGGAGAATTGCTTGGACCCAGGTGGC AGAGGTTGCAGTGAGCCAAGATTGTGCCACTGCACTCCAGCCTGGGCAACAAAGCGAAGCTCTGTCTCAATAAAAAAAAAAATAATAATA ATAAAATACAAATACTTAGAAATTAACTTCGCCTTTGCCTTCAGGCACTTTTGCTACATGTTAGCATCAGAGGCTATTGTACAACTAGAT GGTTATTCCCTGTTTCTTGGCCGATTTTTGGTACCTTTCTTTGAAGAAGAGGGTTAGATTTTAAGAAAGAAAGTGTGCTTATTTCACTCA TGTCTTTGCAGAATTTAACTTTGCTTTACTTTAAAAATTCCAATCATCATGTACCTATAAAGGTTAAAATATAGTGAAAGTTTCTGCTTC ATGTGAATTCAATTCTGAGCACCTGCAGGTCATATCAGGTGTCTGATGCAGTTACCTTTATAGATCGTGGCAGGTCCTTACATTTCAACA GGCTTATGCATTTCCATGGGGGGAAGAGATTCTGTTTCTAGGAAATTACAAAGGGCACACCACTGCAGGGAGTGTAAACAATTCTTTGTT GCAACAGACAAGATTTTTTTTAAAAAAAGAAAAAAGGATGCATTTTAGGTACACAGGGTATGGACGCATTCAACATTTACTTTTATCTCC ACAGATGCCAACCTCCCCTTGTTGCAGGCAGTTGGGCTTTTCCAACTCATTGCTAACAAAGCTGGCATCTGCATTAATTTCAATGAGAAT TTCAAGTACTGAAGATGAAAAGTTGGGGAGATTCATGTTTGAAAAATGAAAAATGAACAAAAAATCCACCTTGTGCAGTGAGATAGCTAA CGCTGATATATCAGGAATAATTTTAAACTATTTTTGCTGTAATGTGTAGCTTTAATGTCTCTTTTCAGTTATGGACCCATAAAAGTATTC CTATATCTTGTGAATAAAGATCATTCTTGTGGACTAGTACGTGGATGCATTCATAGGCTTTGGGAAGCAGTGGTGTGCGTATGTGTGTCT ATATCAATATTTTATGTTTATAACTCTGCGTATTAAGTTTATATAGAAAAAAATAATGTCTTTCTTTAGTGTTTGGGGGACTCAATGGTA ATATGACCATTGCAGTGTAATCTGACTGCTCACTCTAGAGAACACTTCTGTTATACACAATGCACATACAAACATACACCCCTAAAGCGT AGCTAACTGCTCCCACTAGATAATTGCTGCTAAAAACAAAACAAAACAAAACAATACAAAACAAAAAAAACCCTAAGTAATGGAGGAAGA AATAGCATTCTTTTAAAAGGGGCTTTTCTGAAGAGTAAAATGTAAATACAGGACATGTGGGGAGGGTGGGGCCGCCTGCAAAATGTCCTG AAGATGGACAAATAGCCTTTTAAATTCTACTTTTTAACCATCTTTACCGTGTGTGCCTATTTGTATTGCAGATGTGAACTACTATTTTTG GAGGTTGATATCAGTATGTTTTGAAACTGAATTATTACATAAAATCAGAGTAACCTCTTTCTCCATCCTCCTTTTCCACACTATTCTTGC CAAATATTTCTACTGAAACCCAGTTTCAGCAAGGCAAAATGATGGGACTCTCAAACCTCCCTCCTCATCTTCCCTTCCCCTCTGTCTTAT GCCTGGCCTGGCCTTTTTTGTTGTTGTTGGCTTTTCATAAGTAAGAAAAATTTATTGTAGTATTTCAAGACTGCAGAATTTCAAGTGTAT ATCTATAAATCTTTTTTTAAAATCTTCGGCTACACAGTAACATCAATTAAAACAGAAGAGTGAGTCTAAGTCTGTAATATGCTGTAGGAC CAGATAAGATTTTGAATGAGACTAAACTTGACTGCCATATTTTAAGAGGAAATTGAAACTTTATGGTGGAGAATGGATGAGAGCAAGTCT ATGATATATATGTAGTCATTGTATAATTAGAAACACCAAATGCTGAATCCTATCACTGTGTTCTTGGGGGCCAGGCCTTGGATTTGGTTG TCATTTAAACTCCTTGAAGATTATATGTAATTATAATGAGCAGAAGGCAAATAAAGTTTTTGAACAAAAGTCCTTGTTTTCAGTATTTAA AATTTGGTAATATATTTTCTTTTTCAGTTAAACTATCTTCCCCACAAAAAATATTATACTTCAGTTAAACTATCTTCCCCACAGAAATTA TTATACTACGAACAAGTTATGAGTGAGACTGAGAAGCTTGAAGAAGCTGGTTTTTAAGCAGCTCATATAATATTTTGTGTTAAAGAAAGT GTCATTGTTTCCTGTTGGGAGGCAAATAACAACAACAACAAAAGAAATTGTCATGATTCTTTCTGAGCCAAACTGTCACGAAATGTTCTG TGACAGAACCACTACTCTTTTTTCTGCCATTCTGCCTACTGGAGAGTTCTATGTTGTATTTGTTTTTAATCCTTGATTTTAAAAATATTA >6279_6279_8_ARHGEF2-AGO3_ARHGEF2_chr1_155927504_ENST00000361247_AGO3_chr1_36432556_ENST00000373191_length(amino acids)=1368AA_BP=572 MSRIESLTRARIDRSRELASKTREKEKMKEAKDARYTNGHLFTTISVSGMTMCYACNKSITAKEALICPTCNVTIHNRCKDTLANCTKVK QKQQKAALLKNNTALQSVSLRSKTTIRERPSSAIYPSDSFRQSLLGSRRGRSSLSLAKSVSTTNIAGHFNDESPLGLRRILSQSTDSLNM RNRTLSVESLIDEAEVIYSELMSDFEMDEKDFAADSWSLAVDSSFLQQHKKEVMKQQDVIYELIQTELHHVRTLKIMTRLFRTGMLEELH LEPGVVQGLFPCVDELSDIHTRFLSQLLERRRQALCPGSTRNFVIHRLGDLLISQFSGPSAEQMCKTYSEFCSRHSKALKLYKELYARDK RFQQFIRKVTRPAVLKRHGVQECILLVTQRITKYPLLISRILQHSHGIEEERQDLTTALGLVKELLSNVDEGIYQLEKGARLQEIYNRMD PRAQTPVPGKGPFGREELLRRKLIHDGCLLWKTATGRFKDVLVLLMTDVLVFLQEKDQKYIFPTLDKPSVVSLQNLIVRDIANQEKGMFL ISAAPPEMYEVHTASRDDRSTWIRVIQQSVRTEVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFK VSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMW KMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENG QTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETD PFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDA GMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKL GGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKP TRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLC SHAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQA -------------------------------------------------------------- >6279_6279_9_ARHGEF2-AGO3_ARHGEF2_chr1_155927504_ENST00000361247_AGO3_chr1_36432556_ENST00000397828_length(transcript)=2683nt_BP=1815nt GAGACCAACGCGTGCGGGCCGAACCCCTCCCCCCGCCTTCCCCCAACAATACAGGACGCCGGGGTCCGCGCCGCGTCCTCCCTGGTCCCC CCGTCCGATTATGTCTCGGATCGAATCCCTCACGCGGGCGCGGATCGACCGGAGCAGAGAGCTGGCGAGCAAGACCCGGGAAAAGGAGAA GATGAAGGAAGCCAAGGATGCCCGCTATACCAATGGGCACCTCTTCACCACCATTTCAGTTTCAGGCATGACCATGTGCTATGCCTGTAA CAAGAGCATCACAGCCAAGGAAGCCCTCATCTGCCCAACCTGCAATGTGACTATCCACAACCGCTGTAAAGACACCCTCGCCAACTGTAC CAAGGTCAAGCAGAAGCAACAGAAAGCGGCCCTGCTGAAGAACAACACCGCCTTGCAGTCCGTTTCTCTTCGAAGTAAGACAACCATCCG GGAGCGGCCAAGCTCGGCCATCTACCCCTCCGACAGCTTCCGGCAGTCCCTCCTGGGCTCCCGCCGTGGCCGCTCCTCCTTGTCTTTAGC CAAGAGTGTTTCTACCACCAACATTGCTGGACATTTCAATGATGAGTCTCCCCTGGGGCTGCGCCGGATCCTCTCACAGTCCACAGACTC CCTCAACATGCGGAACCGAACCCTATCCGTGGAATCCCTCATTGACGAAGCAGAGGTAATCTACAGTGAGCTGATGAGTGACTTTGAGAT GGATGAGAAGGACTTTGCAGCTGACTCTTGGAGTCTTGCTGTGGACAGCAGCTTCCTGCAGCAGCATAAAAAGGAGGTGATGAAGCAGCA AGATGTCATCTATGAGCTAATCCAGACAGAGCTGCACCATGTGAGGACACTGAAGATCATGACCCGCCTCTTCCGCACGGGGATGCTGGA AGAGCTACACTTGGAGCCAGGAGTGGTCCAGGGCCTGTTCCCCTGCGTGGACGAGCTCAGTGACATCCATACACGCTTCCTCAGCCAGCT ATTAGAACGCCGACGCCAGGCCCTGTGCCCTGGCAGCACCCGGAACTTTGTCATCCATCGCTTGGGTGATCTGCTCATCAGCCAGTTCTC AGGTCCTAGTGCGGAGCAGATGTGTAAGACCTACTCGGAGTTCTGCAGCCGCCACAGCAAGGCCTTAAAGCTCTATAAGGAGCTGTACGC CCGAGACAAACGCTTCCAGCAATTCATCCGGAAAGTGACCCGCCCCGCCGTGCTCAAGCGGCACGGGGTACAGGAGTGCATCCTGCTGGT GACTCAGCGCATCACCAAGTACCCGTTACTCATCAGCCGCATCCTGCAGCATTCCCACGGGATCGAGGAGGAGCGCCAGGACCTGACCAC AGCACTGGGGCTAGTGAAGGAGCTGCTGTCCAATGTGGACGAGGGTATTTATCAGCTGGAGAAAGGGGCCCGTCTGCAGGAGATCTACAA CCGCATGGACCCTCGGGCCCAAACCCCAGTGCCTGGCAAGGGCCCCTTTGGCCGAGAGGAACTTCTGAGGCGCAAACTCATCCACGATGG CTGCCTGCTCTGGAAGACAGCGACGGGGCGCTTCAAAGATGTGCTAGTGCTGCTGATGACAGATGTACTGGTGTTTCTCCAGGAAAAGGA CCAGAAGTACATCTTTCCTACCCTGGACAAGCCTTCAGTGGTATCGCTGCAGAATCTAATCGTACGAGACATTGCCAACCAGGAGAAAGG GATGTTTCTGATCAGCGCAGCCCCACCTGAGATGTACGAGGTGCACACAGCATCCCGGGATGACCGGAGCACCTGGATCCGGGTCATTCA GCAGAGCGTGCGCACGGAGGTGGTTGACTCAATGGTTCAGCATTTTAAAGTAACTATATTTGGAGACCGTAGACCAGTTTATGATGGAAA AAGAAGTCTTTACACCGCCAATCCACTTCCTGTGGCAACTACAGGGGTAGATTTAGACGTTACTTTACCTGGGGAAGGTGGAAAAGATCG ACCTTTCAAGGTGTCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACGGACCTTGCCTGAGCCACT GGAATTAGACAAGCCAATCAGCACTAACCCTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCATGAAATACACACCTGTGGG GCGTTCATTTTTCTCCGCTCCAGAAGGATATGACCACCCTCTGGGAGGGGGCAGGGAAGTGTGGTTTGGATTCCATCAGTCTGTTCGGCC TGCCATGTGGAAAATGATGCTTAATATCGATGAAAGAGACCTCTGGCAGCAGTGTGGAGAATAGATAGAGGAGAAAAAACTAATCTGAGA AGCCAGTTAGGAGGCTTTTCAATCACTAGTTCAGGTTTCAGTCTACATGTTACTTCCTTGAGAAGCAGTGTTTGACACCCTTCTCCCCCA ATCCAGCCATCCCCCAAGTCTGAGTTAGGTATTTCTCTTCTGTATTCCCATAGCACAGTGTAATTCCCCTATAATAGCATGTATCACCTT GAATTATGGGTGTTTATTGTTCTGTCTCTCCTGTTAGAACGAAAGCTCCATGAAGGGATTGTCATTTTATTCACCAGTGTACCCTCTATG >6279_6279_9_ARHGEF2-AGO3_ARHGEF2_chr1_155927504_ENST00000361247_AGO3_chr1_36432556_ENST00000397828_length(amino acids)=737AA_BP=572 MSRIESLTRARIDRSRELASKTREKEKMKEAKDARYTNGHLFTTISVSGMTMCYACNKSITAKEALICPTCNVTIHNRCKDTLANCTKVK QKQQKAALLKNNTALQSVSLRSKTTIRERPSSAIYPSDSFRQSLLGSRRGRSSLSLAKSVSTTNIAGHFNDESPLGLRRILSQSTDSLNM RNRTLSVESLIDEAEVIYSELMSDFEMDEKDFAADSWSLAVDSSFLQQHKKEVMKQQDVIYELIQTELHHVRTLKIMTRLFRTGMLEELH LEPGVVQGLFPCVDELSDIHTRFLSQLLERRRQALCPGSTRNFVIHRLGDLLISQFSGPSAEQMCKTYSEFCSRHSKALKLYKELYARDK RFQQFIRKVTRPAVLKRHGVQECILLVTQRITKYPLLISRILQHSHGIEEERQDLTTALGLVKELLSNVDEGIYQLEKGARLQEIYNRMD PRAQTPVPGKGPFGREELLRRKLIHDGCLLWKTATGRFKDVLVLLMTDVLVFLQEKDQKYIFPTLDKPSVVSLQNLIVRDIANQEKGMFL ISAAPPEMYEVHTASRDDRSTWIRVIQQSVRTEVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFK VSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAMW -------------------------------------------------------------- >6279_6279_10_ARHGEF2-AGO3_ARHGEF2_chr1_155927504_ENST00000368315_AGO3_chr1_36432556_ENST00000324350_length(transcript)=2974nt_BP=1718nt ATGTGCTGCTGCTGTGGCTGCTGCCCGCTGCTGGCCCACCTAGAGCAGGGGTCACTTCGAGAGAGGACCCGGGAAAAGGAGAAGATGAAG GAAGCCAAGGATGCCCGCTATACCAATGGGCACCTCTTCACCACCATTTCAGTTTCAGGCATGACCATGTGCTATGCCTGTAACAAGAGC ATCACAGCCAAGGAAGCCCTCATCTGCCCAACCTGCAATGTGACTATCCACAACCGCTGTAAAGACACCCTCGCCAACTGTACCAAGGTC AAGCAGAAGCAACAGAAAGCGGCCCTGCTGAAGAACAACACCGCCTTGCAGTCCGTTTCTCTTCGAAGTAAGACAACCATCCGGGAGCGG CCAAGCTCGGCCATCTACCCCTCCGACAGCTTCCGGCAGTCCCTCCTGGGCTCCCGCCGTGGCCGCTCCTCCTTGTCTTTAGCCAAGAGT GTTTCTACCACCAACATTGCTGGACATTTCAATGATGAGTCTCCCCTGGGGCTGCGCCGGATCCTCTCACAGTCCACAGACTCCCTCAAC ATGCGGAACCGAACCCTATCCGTGGAATCCCTCATTGACGAAGCAGAGGTAATCTACAGTGAGCTGATGAGTGACTTTGAGATGGATGAG AAGGACTTTGCAGCTGACTCTTGGAGTCTTGCTGTGGACAGCAGCTTCCTGCAGCAGCATAAAAAGGAGGTGATGAAGCAGCAAGATGTC ATCTATGAGCTAATCCAGACAGAGCTGCACCATGTGAGGACACTGAAGATCATGACCCGCCTCTTCCGCACGGGGATGCTGGAAGAGCTA CACTTGGAGCCAGGAGTGGTCCAGGGCCTGTTCCCCTGCGTGGACGAGCTCAGTGACATCCATACACGCTTCCTCAGCCAGCTATTAGAA CGCCGACGCCAGGCCCTGTGCCCTGGCAGCACCCGGAACTTTGTCATCCATCGCTTGGGTGATCTGCTCATCAGCCAGTTCTCAGGTCCT AGTGCGGAGCAGATGTGTAAGACCTACTCGGAGTTCTGCAGCCGCCACAGCAAGGCCTTAAAGCTCTATAAGGAGCTGTACGCCCGAGAC AAACGCTTCCAGCAATTCATCCGGAAAGTGACCCGCCCCGCCGTGCTCAAGCGGCACGGGGTACAGGAGTGCATCCTGCTGGTGACTCAG CGCATCACCAAGTACCCGTTACTCATCAGCCGCATCCTGCAGCATTCCCACGGGATCGAGGAGGAGCGCCAGGACCTGACCACAGCACTG GGGCTAGTGAAGGAGCTGCTGTCCAATGTGGACGAGGGTATTTATCAGCTGGAGAAAGGGGCCCGTCTGCAGGAGATCTACAACCGCATG GACCCTCGGGCCCAAACCCCAGTGCCTGGCAAGGGCCCCTTTGGCCGAGAGGAACTTCTGAGGCGCAAACTCATCCACGATGGCTGCCTG CTCTGGAAGACAGCGACGGGGCGCTTCAAAGATGTGCTAGTGCTGCTGATGACAGATGTACTGGTGTTTCTCCAGGAAAAGGACCAGAAG TACATCTTTCCTACCCTGGACAAGCCTTCAGTGGTATCGCTGCAGAATCTAATCGTACGAGACATTGCCAACCAGGAGAAAGGGATGTTT CTGATCAGCGCAGCCCCACCTGAGATGTACGAGGTGCACACAGCATCCCGGGATGACCGGAGCACCTGGATCCGGGTCATTCAGCAGAGC GTGCGCACGGAGGTGGTTGACTCAATGGTTCAGCATTTTAAAGTAACTATATTTGGAGACCGTAGACCAGTTTATGATGGAAAAAGAAGT CTTTACACCGCCAATCCACTTCCTGTGGCAACTACAGGGGTAGATTTAGACGTTACTTTACCTGGGGAAGGTGGAAAAGATCGACCTTTC AAGGTGTCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACGGACCTTGCCTGAGCCACTGGAATTA GACAAGCCAATCAGCACTAACCCTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCATGAAATACACACCTGTGGGGCGTTCA TTTTTCTCCGCTCCAGAAGGATATGACCACCCTCTGGGAGGGGGCAGGGAAGTGTGGTTTGGATTCCATCAGTCTGTTCGGCCTGCCATG TGGAAAATGATGCTTAATATCGATGAAAGAGACCTCTGGCAGCAGTGTGGAGAATAGATAGAGGAGAAAAAACTAATCTGAGAAGCCAGT TAGGAGGCTTTTCAATCACTAGTTCAGGTAAGAGATGGTGATGGTCTAATGTGGGATGGAGAGGAAGGATTAAGCTGAAAAAATAGGTTT AAGAACCATGTCCAGAAAAAAAAAACTTTGGGTGTAGTACTGGTACATGGAACGGATTGGAAAAAAATAGACCAGAGCTTTACTAGATTT TTGAAAGAATTGTTTTTGCAAATAAACTACAAGCCTGGCATATCAGTCAAGGTTCAGAACCTAGAGAAGCAGAACCAGTACGAAGTATAG AGAGAGAGTTTATGCAATTGTAGGGGCTAGCTAGGCAAGTCTGAAATTTTGGGGGCAGGCTGTCAGGAAGGGCAGGGAAATTCAGGCATG GGCTGAAGCAGTTATCTATAAGTGGAATTTCTTGCTCTCAGGGAAGCTTCAGCCCTACTTTTAAGACCTTTCACCTAATTGAATCAGGCC CATCCACATTATTCAGGATAATCTCCATTACTTAAAGTCAACAGATTATGGATTTTAATTACATCTACAAAATACCTTCATAGCAACACC TAGATTAGTGTTTGATTAAACAAATGGCAGCTGGTAGCCTAGCAAGTTAACACATTAAAAACAACACCTGCCATGATGGCTTACACTTGT AATCCCAGCACTTTGGGAGGCCAAAGTGGGAGGATCACTTGAGATTAGGAGTTTGCGATCAGGCTGAACAACATAGTGAGACCTGATCTC >6279_6279_10_ARHGEF2-AGO3_ARHGEF2_chr1_155927504_ENST00000368315_AGO3_chr1_36432556_ENST00000324350_length(amino acids)=738AA_BP=573 MCCCCGCCPLLAHLEQGSLRERTREKEKMKEAKDARYTNGHLFTTISVSGMTMCYACNKSITAKEALICPTCNVTIHNRCKDTLANCTKV KQKQQKAALLKNNTALQSVSLRSKTTIRERPSSAIYPSDSFRQSLLGSRRGRSSLSLAKSVSTTNIAGHFNDESPLGLRRILSQSTDSLN MRNRTLSVESLIDEAEVIYSELMSDFEMDEKDFAADSWSLAVDSSFLQQHKKEVMKQQDVIYELIQTELHHVRTLKIMTRLFRTGMLEEL HLEPGVVQGLFPCVDELSDIHTRFLSQLLERRRQALCPGSTRNFVIHRLGDLLISQFSGPSAEQMCKTYSEFCSRHSKALKLYKELYARD KRFQQFIRKVTRPAVLKRHGVQECILLVTQRITKYPLLISRILQHSHGIEEERQDLTTALGLVKELLSNVDEGIYQLEKGARLQEIYNRM DPRAQTPVPGKGPFGREELLRRKLIHDGCLLWKTATGRFKDVLVLLMTDVLVFLQEKDQKYIFPTLDKPSVVSLQNLIVRDIANQEKGMF LISAAPPEMYEVHTASRDDRSTWIRVIQQSVRTEVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPF KVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAM -------------------------------------------------------------- >6279_6279_11_ARHGEF2-AGO3_ARHGEF2_chr1_155927504_ENST00000368315_AGO3_chr1_36432556_ENST00000373191_length(transcript)=20865nt_BP=1718nt ATGTGCTGCTGCTGTGGCTGCTGCCCGCTGCTGGCCCACCTAGAGCAGGGGTCACTTCGAGAGAGGACCCGGGAAAAGGAGAAGATGAAG GAAGCCAAGGATGCCCGCTATACCAATGGGCACCTCTTCACCACCATTTCAGTTTCAGGCATGACCATGTGCTATGCCTGTAACAAGAGC ATCACAGCCAAGGAAGCCCTCATCTGCCCAACCTGCAATGTGACTATCCACAACCGCTGTAAAGACACCCTCGCCAACTGTACCAAGGTC AAGCAGAAGCAACAGAAAGCGGCCCTGCTGAAGAACAACACCGCCTTGCAGTCCGTTTCTCTTCGAAGTAAGACAACCATCCGGGAGCGG CCAAGCTCGGCCATCTACCCCTCCGACAGCTTCCGGCAGTCCCTCCTGGGCTCCCGCCGTGGCCGCTCCTCCTTGTCTTTAGCCAAGAGT GTTTCTACCACCAACATTGCTGGACATTTCAATGATGAGTCTCCCCTGGGGCTGCGCCGGATCCTCTCACAGTCCACAGACTCCCTCAAC ATGCGGAACCGAACCCTATCCGTGGAATCCCTCATTGACGAAGCAGAGGTAATCTACAGTGAGCTGATGAGTGACTTTGAGATGGATGAG AAGGACTTTGCAGCTGACTCTTGGAGTCTTGCTGTGGACAGCAGCTTCCTGCAGCAGCATAAAAAGGAGGTGATGAAGCAGCAAGATGTC ATCTATGAGCTAATCCAGACAGAGCTGCACCATGTGAGGACACTGAAGATCATGACCCGCCTCTTCCGCACGGGGATGCTGGAAGAGCTA CACTTGGAGCCAGGAGTGGTCCAGGGCCTGTTCCCCTGCGTGGACGAGCTCAGTGACATCCATACACGCTTCCTCAGCCAGCTATTAGAA CGCCGACGCCAGGCCCTGTGCCCTGGCAGCACCCGGAACTTTGTCATCCATCGCTTGGGTGATCTGCTCATCAGCCAGTTCTCAGGTCCT AGTGCGGAGCAGATGTGTAAGACCTACTCGGAGTTCTGCAGCCGCCACAGCAAGGCCTTAAAGCTCTATAAGGAGCTGTACGCCCGAGAC AAACGCTTCCAGCAATTCATCCGGAAAGTGACCCGCCCCGCCGTGCTCAAGCGGCACGGGGTACAGGAGTGCATCCTGCTGGTGACTCAG CGCATCACCAAGTACCCGTTACTCATCAGCCGCATCCTGCAGCATTCCCACGGGATCGAGGAGGAGCGCCAGGACCTGACCACAGCACTG GGGCTAGTGAAGGAGCTGCTGTCCAATGTGGACGAGGGTATTTATCAGCTGGAGAAAGGGGCCCGTCTGCAGGAGATCTACAACCGCATG GACCCTCGGGCCCAAACCCCAGTGCCTGGCAAGGGCCCCTTTGGCCGAGAGGAACTTCTGAGGCGCAAACTCATCCACGATGGCTGCCTG CTCTGGAAGACAGCGACGGGGCGCTTCAAAGATGTGCTAGTGCTGCTGATGACAGATGTACTGGTGTTTCTCCAGGAAAAGGACCAGAAG TACATCTTTCCTACCCTGGACAAGCCTTCAGTGGTATCGCTGCAGAATCTAATCGTACGAGACATTGCCAACCAGGAGAAAGGGATGTTT CTGATCAGCGCAGCCCCACCTGAGATGTACGAGGTGCACACAGCATCCCGGGATGACCGGAGCACCTGGATCCGGGTCATTCAGCAGAGC GTGCGCACGGAGGTGGTTGACTCAATGGTTCAGCATTTTAAAGTAACTATATTTGGAGACCGTAGACCAGTTTATGATGGAAAAAGAAGT CTTTACACCGCCAATCCACTTCCTGTGGCAACTACAGGGGTAGATTTAGACGTTACTTTACCTGGGGAAGGTGGAAAAGATCGACCTTTC AAGGTGTCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACGGACCTTGCCTGAGCCACTGGAATTA GACAAGCCAATCAGCACTAACCCTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCATGAAATACACACCTGTGGGGCGTTCA TTTTTCTCCGCTCCAGAAGGATATGACCACCCTCTGGGAGGGGGCAGGGAAGTGTGGTTTGGATTCCATCAGTCTGTTCGGCCTGCCATG TGGAAAATGATGCTTAATATCGATGTTTCTGCCACTGCCTTCTACAAAGCACAACCTGTAATTCAGTTCATGTGTGAAGTTCTTGATATT CATAATATTGATGAGCAACCAAGACCTCTGACTGATTCTCATCGGGTAAAATTCACCAAAGAGATAAAAGGTTTGAAGGTTGAAGTGACT CATTGTGGAACAATGAGACGGAAATACCGTGTTTGTAATGTAACAAGGAGGCCTGCCAGTCATCAAACCTTTCCTTTACAGTTAGAAAAC GGCCAAACTGTGGAGAGAACAGTAGCGCAGTATTTCAGAGAAAAGTATACTCTTCAGCTGAAGTACCCGCACCTTCCCTGTCTGCAAGTC GGGCAGGAACAGAAACACACCTACCTGCCACTAGAAGTCTGTAATATTGTGGCAGGGCAACGATGTATCAAGAAGCTAACAGACAATCAG ACTTCCACTATGATCAAGGCAACAGCAAGATCTGCACCAGATAGACAAGAGGAAATTAGCAGATTGGTAAGAAGTGCAAATTATGAAACA GATCCATTTGTTCAGGAGTTTCAATTTAAAGTTCGGGATGAAATGGCTCATGTAACTGGACGCGTACTTCCAGCACCTATGCTCCAGTAT GGAGGACGGAATCGGACAGTAGCAACACCGAGCCATGGAGTATGGGACATGCGAGGGAAACAATTCCACACAGGAGTTGAAATCAAAATG TGGGCTATCGCTTGTTTTGCCACACAGAGGCAGTGCAGAGAAGAAATATTGAAGGGTTTCACAGACCAGCTGCGTAAGATTTCTAAGGAT GCAGGGATGCCCATCCAGGGCCAGCCATGCTTCTGCAAATATGCACAGGGGGCAGACAGCGTAGAGCCCATGTTCCGGCATCTCAAGAAC ACATATTCTGGCCTACAGCTTATTATCGTCATCCTGCCGGGGAAGACACCAGTGTATGCGGAAGTGAAACGTGTAGGAGACACACTTTTG GGTATGGCTACACAATGTGTTCAAGTCAAGAATGTAATAAAAACATCTCCTCAAACTCTGTCAAACTTGTGCCTAAAGATAAATGTTAAA CTCGGAGGGATCAATAATATTCTTGTACCTCATCAAAGACCTTCTGTGTTCCAGCAACCAGTGATCTTTTTGGGAGCCGATGTCACTCAT CCACCTGCTGGTGATGGAAAGAAGCCTTCTATTGCTGCTGTTGTAGGTAGTATGGATGCACACCCAAGCAGATACTGTGCCACAGTAAGA GTTCAGAGACCCCGACAGGAGATCATCCAGGACTTGGCCTCCATGGTCCGGGAACTTCTTATTCAATTTTATAAGTCAACTCGGTTCAAG CCTACTCGTATCATCTTTTATCGGGATGGTGTTTCAGAGGGGCAGTTTAGGCAGGTATTATATTATGAACTACTAGCAATTCGAGAAGCC TGCATCAGTTTGGAGAAAGACTATCAACCTGGAATAACCTACATTGTAGTTCAGAAGAGACATCACACTCGATTATTTTGTGCTGATAGG ACAGAAAGGGTTGGAAGAAGTGGCAATATCCCAGCTGGAACAACAGTTGATACAGACATTACACACCCATATGAGTTCGATTTTTACCTC TGTAGCCATGCTGGAATACAGGGTACCAGTCGTCCTTCACACTATCATGTTTTATGGGATGATAACTGCTTTACTGCAGATGAACTTCAG CTGCTAACTTACCAGCTCTGCCACACTTACGTACGCTGTACACGATCTGTTTCTATACCTGCACCAGCGTATTATGCTCACCTGGTAGCA TTTAGAGCCAGATATCATCTTGTGGACAAAGAACATGACAGTGCTGAAGGAAGTCACGTTTCAGGACAAAGCAATGGGCGAGATCCACAA GCTCTTGCCAAGGCTGTACAGATTCACCAAGATACCTTACGCACAATGTACTTCGCTTAAATAGTCCAAGTATATTCTCTGAGAGGAAGT ACTGAAAGATGAATTGACATACAACGTATGTTTCCAGTGAAGTCAATTGAGTAAGGACACCTCCAGCCATACAGAAACCAACACTGTGTG GGGGCCAAGGTCTGATCCTTATGTTAATACAAGGAAGATTGTTTACTTCATCAAGGAACACAGCATCATTATGCAATATGAAACCAGCCA ACTGCTTTTTGTGCGGTCTCCTATAGGAAGTATCGCAATTGTTTTGTTTTCATTTCTTGTAGTCTAACCCTTTTAATGCCTTTACCTCAA GTTGCTTGGCAGCACAACTATCTTTGCAAAAAAAAGTAAAGAAAAAGTAAATGATGGTTTAAAAAATACACACCTTCATGAATAATCAAA GTGATTTTTCAGAATTATGTGTGCAAAAAATTAATGTGCATTCATATATTCTTGTAAAAGGTGTCTGTGTATTTTTAAAATATATACATC CATACTTCATATGCATATATATCTAGATCTGGATTGATAATAGATATATATGTGTCTGTTATATATTTTAGAGTTCATTCCATTGGGGAA TTTTCTTTCCCTTTTATTCTACCCCCACTACCGCCTTTATTTCTCTATTTCCCTTGCCTTCATCACCTACATTTTTTTCCCAGTCCTACC AGTGACATTCAAATGTTGATGTATCTGGTTCGTTTGAATATAAAATATGGCAAACTAGAATTCTACTTTTATTTTGCATACCCTACTCCT GACTCCTATCTCATACACAATTCTGAGTTCTCAACTCTTGATATTGCTGTCTTAAGAAACAAAATTTTATATATATATGTATACATACAT ACACAGACACAGACACACACATATATATACATAAAATAACTTTCTGTGAGAGTGCGTCTCTCCCCTCCCACTCAGAACATACATTTACCA TTTGCGCAATTTGTATATAAGCAGTAGCAACCTGAACTATTCTTTTTCTTTTTTCTTTTTCTTTTCTTTCTTTTTTTTTTTTAATGAGAC AGAGCCTCGCTCTGTCACCAGGCTGGAGTGCAGTGGCGAGATCTCGGCTCACTGCAACTTCCGCCTCTCGGGTTCAAGCAATTCTCCTGC CTCAGCCTCCCGAGTAGCTGGGTTTACAGGCATGTGCCACCACACCCAGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCGTGT TGGCCAGGATGGTCTCGATCTCTTGACCTTGTGATCCACCCGCCTCGACCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCACCC GGCCTACTATTCTTTTTCTTTAGTGAGTTTGTTAAAGCTGCTATAAATATAAAACCTGTCAGAAGTTGTAACTTTCTCTCTGGTAAGTGA TGTGTATTCTGAAGCCTTCTGTTTCTATGGGTTATACATGGAAATTCTTTAAAGGTTTTATAAAGGGTAAATATTTTAAAAGATTAGAGC TCTGTAGGGTTGAGACCTCTGAAATTGAGTAGAGAGAAGAGTTTGTTGAGGGATTTTTTTGTTTTGTTTTTTGATAGTTTACTTGCTGCC TCTCATACCTTAATGTGATTTTCATATATTTTTTATATATATATATGTATGTGTGTGTATATAAACACATATGTATGTGTTTGGAAGTAT AGCTTCCTTTTCTTTTATATTTATTAGAATAGTGCTTTAATAATTATAGAATTGTATTGGCAGCATCTTTTATAGAAATATAATCATGTT TATTTTAAGAACTGACAACTTGTTTTTGCTATCTTTTAGTGCAATAAGCAGTTTTAAAGGAAAGTTGTGTCTGCATCTTTACCATGGATA GTAGGAGGAACAGGCACCTCCATAGTTTAAAAGGGCAAAGAATACAGCCTTAATTTCAGAAGGAAAGTTTTGTAATTTTCAGTTTTAAAG CATATCTTTTAAAATTCATCATGATAAAAGGCTGGACGCGGTGGCTCATGCCTGTAATCCTAGCACTTTGGGAGGCTGAGACAGGTATAT CACCGGAGCTCAGGAGTTTGAGACCAGCCTGGCCAACGTGGTGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCTGGGCGTGGTAGT GGGCACCTCTAATCCCAGCTACTCGGGAGGCTGAGGCAGGATTGCTTGAACCTAGGAGGCGGAAGTTACAGTGAGCCAAGACTGCACCAT TGCACTCCAGCCTGGGCAACAAAACCAAAACTCCGTCTCAAAAGAAAAAAAAATCATAATGAAAATGAAGTGAAATTGCCTAAATGAGTC CAACTTGAATATTAGAAATAAAGTTGAACTTTTATATAATTGTGAATAGCTTAACATATTTAAATTATTTGCAAATAGATTGTGTTTATT GAAGAATCATATTGGCTAGATGCCCATTTTCATTTACTAAAATGAATCAGGAAAATGCAAGATGATATTTTAAAACTTTTGCTAATGTAT CACCAGTATAACTTTCCTTTTAAAATTAAGGTGATAGTAACAAAGGAAGTTAGGACTTTGATCATTTTAAATCAGTTAAATCACTGAAAC GTGGGAAATTGTTTTACAAAACTTTTATTGATTACACTTTAAGGTATTAAAAAGTACTATAAAGCTATCAAAACTGAGTTTATCAGTAAC ATTGGATTCAGGGGAGCTTTGCACTTTGTAACTCATGAAAATTGCATTTTGATTTTTTTTTTTTTTGCACTGGTTCAGAGTATAGATACT ACAGATTGTTTCCAGTGGGCATTGTTGTTAGCCTTTCAGAATTCCATCTGCACGTGAAACCTAATGGATTTAGATCTTTAGTTTCTCTCT TACCTGTAATCCACTATTATTGCCAATTCACTGTATTTTGAGCCTAAAATCTGAGCCCATGTCCTCTGACAGGCATGAAATCTTTTGTCC CTCTGCCAGAAAACTAAGAAAGTACTGTATTTTGTATGTTTATTATTTTGAAGTGTCTGAAATGCAATTTACAACACTGTTGCAAAGAAC TTTACAAAAGGTAATATTTGTATCGTATATACATTTTTTCTCCCAGCCTTCTCCCATCTCCTCCAGAAAAATTTCCTATAAAGATGGATT TTTTTACACTGAAATTTTACTGAATATAGTCAGGATCATGGGCAAGAGAAGAAAATAGTATACCCAAGATGATAAAAATTTAATTCGTCT ATGCTTGATCAGTGTGAGTAAAACATCTTCCTTTATCATGGGAGCTGCACAGATTCATGTGGGAAACTTTAGGGAATGACTGTAGATACC CTTTCTCTATGTACTCTCTCACCTAATTTTCAGTCACTCATATATGCTAGAGTGGAGCCCTTAATTTAAATCTATTTGGAAGGACTTTTT TAAGAGGAAAAATATTTTTTCTAAATTATAAAGCTTTACCTTTTGAGTGATTTCTTTTTTAGAGTGCTCTTACACTAGTCAGCATTGCTA GTTTAAAGTTGATTAACTTGAAAGAGTATGTATACTATATTTCTATTTTGCTAACAAATTGGTATATTAATTACCATTGGTTCTTAATTA CAAGAAAACTTGTGCTTAGAATTTTAAGATAAAAGGCTAAGTGACAAATGCTTCTTGAAATTTGTCCTATTTATTGTTGCATTTCTGGTG TAGAATTTCTAATCTTTTTTATTTTAAAAAAGTTTTTTTTTTTAAGTTAAACATGAAATTCACAGTGACCCTTCTGCTCCTGCCCTTGCT CACTAACTATATCATGAATGCTAGATTTTGGTCTTCTTTTTTCTGTGATGTATCTTACGAGACTGACTGTAAAATATCAGTCTGGCAACT AGATAATTGATTTTCATATGAAGAAGAGTTGGGAGTTTAATGTATATTCTTGATGGTTAATGTGTCTACATAAAGTGCTGATACATGTAT TATATCACAGTATCAGGTTACTGGCATGGAGGACCATACACTTACAATATTGTAGCTGCTATATTTATTTAAGTAGATTCTGACAGTTAC TGCACTAAACAGTAAGGAGATAAGCAGGATTCAAGGCTAGTGTTAGACCCTTTTTTTTCCTAAGAGTAAGGACACGGAATATCAAAGTAA CAAAGGGTGCTGCCATTTTAGTTTCAATTTAATATCAGGATATTCTTTGTTTTAGAAATGTAGATTTTGACTTTTACAGTTTGAAAAAGG GTACCTCAGCCTCTTCAGTACTGGTTTTTTGGCACATTTCAACAGAAATATTAGATTCCCTTTCTTTTTCTTAATAGTGATCTTCTAACA AGTTTCTTGGAAAAACTATCATTCTAAGGGAAATCCCTGTTTATAACCTATTAATATATTTCTATTCCTAGAAGAGAGTCTAGCAGGGAT TCTAGTAGGAATTACTGAGTGTTTTGGAAGGCACTTGATAGAGGCATCTCTGCTTTCCAGCACAGGGATTCTCAGCCTTCTAAAGATCTA GACCAGTTTCCAAGCTAGCTTCTCCACAGCCCACCACTGCCTAGTGTTTGCTTGTGTATTCTCTAATGGATTTTAGGAGGATAGGCCTTC TGACAGAGTCATGAAAGACTGAAGGCATGTCTAGGGAAATAAAACCTGACTTGCCCTTCAGCAGGAATGACTGGCAGCGGATCTCTGTGT TCAAGGAAAGGGTGAGCGCTAAGCATGCCAGTGATGGATCCGAAGTATTTAGATGGATTGCAGACCAGGAATTAGAGACCGTTTGTGACT CAAGGAACTTGATGGATCTGTTTAGAGCCCTACATGAATTTGCCAAGGGCAGTGATTTTTATGAAATTCAAGAAGCAAACGACTTCGATA CAGCTAGAATATGTTGCAGTCTTCCTATTTCAAACTTGATTTTAATATTTTTACCAAGAAGTTTAACTGACAACTCTGCAAAATTTTCAT TCAGTATCATTAAACCTGAGTTAAATGTTTGCTTAGCTTATCCTCTTAGATGTTCTTCTGTTGAACAGGCAGGTTGCCCTTAACAGTAAC TTGCTACTTAAATTACCTTTTATTAGTTAGTCAAGCTGCAAAAATATCATTAGTGTGGCGTCTTTATTTTGGCTTTATCCATATGAAGTA TTCATTATTTTCATTCTTTTTGAGAATTCATAAATGTCTTAAAGCTTCAGTAAGAATTGTTGGGAGGTTTGACATCAAGTAACGCCTTCC TGTGTAGCAGTATAACCCTAATTTAGAACTCTTGTTTTCCTATTTCAGTCCTCATATTTGATCATAGAAAAGCACTTTTGTGATTCTATA GGAGTCAAAAAATCAGCCAAGAGTAGGTAAGTCAGTCAGCACAGAAATCAGAAAGTGAGAATTTTCTCCAAAAAATCTTTTTAAAAAAGT CCTGCTTATACTAAGAACATTCTTGATCCGTTGCAGTGTTAGAAATGACACTGTGATTAGTGAAAGCCAAGCTGAGTCCCAGGAAGCAGG GAGGGGGAGTGTGTGTGTGTGTATATGTATGAGTGTGTATATATATAATCTCACACACACACACAAAGGGAAAAATTATTTTGACTTTTT TCCTACTTTTAAAATGGTACATTTAAGTTTATAATTTTCCATGTCAGTCAACATAATTTTTTAAACTAAGGTATAATGGTCAAGGCTTGT GCTAATATTACCTACTACTCATTGAAATTTATATTACTTTACCCATCAAAACTAGTACTCCAGATGTTTACATCATTGATTAAATCTCAA GAATCTTTTGTTCTTAAAATATGGAAGTTAAAGATTTTAATTTGAATTAAAGATAGAAGGATGGTAAATTCAATATAGAGGGTTGAGATT TACCAGTGAGAAACCCTGTTGAAGTATCAGGTAAATGGTGTGACAAAATTAGAATCCTGTCAAATCACCTATCCAGCCATCGGGGTCCCT TCCTTTTTTAGACTAATTTCTAAGGTAACCAGAATCTAATGTATCTATGTTAGGGTCTCAGTAAAGCAAAGACGTTTGTCAGGGCGTAGA CTCTTGAGTTAAATTTTTTAATCATTTTTTAAAGCAAGGCGGTTCTTAGAAAGTGCCTTTTCAGAAGATGGTGCTGTAGATTTTTATTTT TCAAGTAGCACGAAGCTAAGAATTTTAAAGATAAATTATTTTAGAACTCCAAGAGTGTGACAGTTTCATAAAAATAATGTTAGTTGTTGT CTTGAATCTCGTCCAAGGGAACCAAGGAAAGCTTTTATGCAGTAAAGTATCTAGGTAAATGCTCACCAAATTTATTTTGTAAATTTGAAA ACAAAATATTTAGTAGAATTACCTCTTTTAATTCCCAACTGTGTTGGAGGAAATCCATAATGCACATAAAACAGCAAACCTACTTAACTT TTTAACAAGATTATGGGTATAGTACCAATGTCCAAAGGGAAATGTAACTTGCCTGGAATCATAGGCAACATTTTCTAATTAATCTTTTTT TTTTTTTTTTTTTTTGAGACAAAGTCTTGCTCTGTCACCTAGGCTGGAGTGCAGTGGCTCAATCTCAGCTTACTGCAAACTCCGCCTCCC GGGTTCAAGTGATTCTCGTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCATGCACCACCACACCCGGCCCTAATTAGTCATTATTAA GGAGGACTGCTCATAAAGGCAGTACCAAATCATCATTCAGATCAGCTTAAGTGAGAAAGCAAAATGATAATCTCTATTGTTAGAGAAATT TTCTTTTCTAGACACCAAGGAATATTTTAAATGATTTTTTATTTTTTCTAGGATGCAGGAACTATGAAAAATGATGACAAGGCATTTAAA AGGGTATGATCAGTTAAATAGAAGTAGGGTCTGCAAATTGTGCTTAAGGGGAAATAAGCAAAAGAAAGGAAAATAGTAGAACCTTTCATA CTAATTAGAAATGTAGTTACCTACCAGAGGGCAATTTTGCTCCATACCAGGAAGCAGTAAATAGCAGTAAATGATCACCTAGGCACTTCT TTCCTGTGAATTTGGTGAGCATTCTTCCAGAAAAGAAGACTAAAAGCAAACAACAACAACAACAAAAAATACCACACCTCAGTAACCTTG TATGCTGCATTATATAATAATGATAGTAAAATTATATTGTTTGGAGTGTACTGTGTCTGTTTGCAAATATACATGCACATTAAACTTTTT TGTTTTTATAATGTCTTAATAGCAATTATGAGTTTATTTTTGTTAAGATTAATTTTTCTATTGTGATGTTTATATTTATTGGCAATTTGT ATGCAACTTTTATATTTTGCTTGTCGGTTTTAAGGTATTTTATTTTTATAGATATTTCTAGCTTTCCTCATTCTTTGTAATAGCAGCAAA GATTAAGATGGAGTGTTAATATACCAACCAAACTACGAATTCCATAAACTCTAGAGTTTGGATTTTTACCAATAAACCATTAACACTATT TTGTAACTTAGAATATTTAATGTTGTTTATATAGTGGGCATTAAAGACAGTCTTTAGACAGATTTCTACATGTGGAGGGGAGGTGGGGCT TTCCTGTAAGTTTGATCCTTTTTTTCCCCTTTAGTAGCAAACTAACATAACAGATTGGATTTATTTTACCTGACTACAGTTTTGGGGAAA CCTGTCAAATAAATAATTGTTACATGCCTTTTTTTTTTAAATTTAAGCACATTGAAACTGCTTAAATGGTCACATTTTTCAGCATTAGGA TTAAGATACCATTTTTGTAGGCCTGGAAAACAAATAGCAAATGATTCAAAATTCATTGAATTGACTTTGAAATGAAACTTTTCCCCCATA ATTTGTTATATGGAAGATTTGCTACCCTGATCTTTTCCCTAGCATACTTCTAAAGTTGATTGAATCCCTGAGTATCAATGAAGAAATCAG AGTTTAAGTGGCTAGGGAGAGCCAGGTATAAAGACTGATTAATAGAGTACTTCAGCTAATTAAAAATTTAAATAGTAATAATTTATGAAT GTGAATAAATTGGAAGGCAGCAAAAAGCATGATTATAGAATATTAAGTTCAATTATATATAGACAGTCCAGTTTCCTAGTGAATAGGTCA AGATTATTTGTTTTGTTTTGTGGCACTATCATAGTTCACTATAACTTCAAACTCCTGGGCTCAGGCTATCCTCCCACCTCAGCCTCTGAA GTAGCTGGGACTACTCACATGCGCCACCATGCCCAGCTAATGGTTTTTTTCTTTAGAGATGGGGGTCACTATACTGCCCAGGCTGGTCTT GAACTCCTAAGCTCAAGTGCTTCTCCCACATCAGCCTCCCAAAGTGCTGGGATTACAGCCATGAGCCACTGCATCTGGCCAAGATCAAGA TTATGGATATTGGTATGTTAACTTTTAAAATAAAAGTACATGGGCTGGGCGCAGTGGCTAACGCCTGTAATCCCAGCAATTTGGGAGGCC GAGGCAGGCAGACCACCTGAGGTCAGGGGTTCGTGACCAGCCTGGCCAACATGGCGAAACCCCGTCTCTACTAAACATACAAAAATTAGC TGGGCATGGTGGCACATGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCACTTGAACTCGGGAGGCGGAGGTTGCAGTGA GCCAAGATCGCGCCATTGCACTCCAGCCTGGGCAACAAGAGTGAAACTCCATCTCAGAAAATAAAAATAAAAATAAATAAAAGTACATGA AAAAAGTATATTCCCTTAAGCAGGTAAAATACTTGCATTGTATTTTTACATCATGAATTTGCTTGTTAAGAAATTTCTTTTCTGTAAGTG GTTAAAAGATAAACTGTATTCCATCCTCTGGGTTTTCAATTCTAAATTATTGGAGCTCAATGTATGACATTTTACTGTAGTGTATTCCAC TGAGAGGCAAGGAAATGGGAAAGTGTCAGGTAATTATAAATGGGAAAATTTTATTTTTATATGATGTAAAGTTTTACAGTTTAAAATAGA TCAGCATGTGATTTCTTGTAGAGATTAGCCATTTCATTTCTTTTTGCATTTTTGCCAGTTACATTAGTTTGCCCTATGATATACTATTCT GAGATACTTCAGCCCCGCACACATCAAGTACTAATTGTATACAGATAGTACAGATTTGTACTCTGATTATAAGAATTTGTTACTACTAAT TAAAAGCAAATTAATGTGGCTGGGCGTGGTAGCTCACACCTGTAATCCCAGCACTTTGGGTGGGCGGCTGAGGCGGGCGGATCACGAGGT CAGGAGTTGGAGACCAGCCTGCCCAATATGGTGAAACCCTGTCTCTACTAAAATTACAAAAATTAGCTGGGCTTGGCGGTACGTGCCTGT AATCCCAGCTACTGGGAAGGCCGAGGCAGGAGAATGGCTTGAACCCAGGAGGCGGAGGTTGCAGTGAGCCAAGATCACACCACTGCACTC CAGCCTGGGCGACAGAGCAAGACTCCGTCTCAAAAAAAAAAAAAGCAAAATATTTTTGCTGTGATTGTATGTCCCCTTTTAAGGATATTT ATTGCGCTTATAACCTTAATAGTTGTATTCATTACATTTCAACATGTCCAAGGTTAGCAGACATGTAGTTCCTGAAAACCAACATTTTAA AAGTTGCCTCTGGGCTGGGCATGGTGGCTCACGCCTGTAATCCCTGCACTTTGGGAGGCCGAGGTGGGCGGATCACGAGGTCAAGAGATG GAGACCATCCTGGCCAACATGCTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCTGGGTGTGGTGGCACACGCCTGTAGTCCCAGC TACTTGGGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGAGGCGGAGGTTGCAGTGAGCCAAGATTGCACCGCTGCACTCCAGCCTGGC AACAGAGCAAGACTCCATCTCAAAACAAACATACAAACAAAAAAAGGTGCCTCTGGTCCTGTGTTTTCTTTTTCCTTCTGAAAGTTCATA GAAACCTGGCATATAGAGCTTATTTTGCTGTTTTAACTGGTTGGCTCCACAAATCCTGCTACCTGACATCAGTACAGCTTGACCGCAGTG AAGTACTTGATGGCTTGTTCATGTTTAGTTCACCTCTTTAGAAAGAAAGCTTTGTGGCCAGGTGCAGTGGCTCACACCTGTAATCCCAAC ACTTTGGGCAGCTGAGGTGAGCAGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGCAAAACCCTGTCTCTTCTAAAAA TACAAAAATTAGCCGGGTGTGGTGGCGGAGGATGCAGTGAGCCAAGATCGTGCCACTGCACTCCAGCCTGGGCAACAGAGTGAGACTCTG TCTCAAAAAAAAAAAAAAATCGTTGTGCAGTAATAGATCATCCCAAAAAAGAATTGCCATGAACAGCGTTATGCGTAGAAAACAGATGGA AGTGTTGGTCATTAGAGCCTTGCTTTTTAAATTTTATTCTTTCCAAAAATTGGCGGTATGCTATCTATAATTTTATGTTTGATGTTGAAG AGGCAACACCAGAGACTAGAGAGGGAGATTACTCTGATATTTAGTGCCTAAAACTTTCATCTTGGCCGGGCACGGTGGCTCACACCTGTA ATCCCAGCACTTCGGGAGGCCGAGGCAGGCTGATTACCTGAGGTCAGGAGTTCGAGACCAGCCTGGACAACATGGCAAAACCCGTCTCTA CTAAAAATACAAAAATTAGCCAGGCATGGTGGTGGGCGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCGAGAGAATCGTTTGAACCCG GTAGGCGGAGGTTGCAGTGAGCCGAGATCATGCCACTGCACTCCAGCCTGGGCGACAAGAGTGAAACTCCGTCTCAAAAAATAATAATAA TTTTAAAAATAAAAGACAAAACTTTCATCTTTATTTCATGGCTTTATTTCATCTTTATTTCATTTTTGGTTGGGAAAACAAACAAAAATC TCTTAAGTTAGTCCTTTAATAGTCTTTTTAGAACCAAAGAAGGAAAGACTGCAAAAATGTTGCATACGTGACTCTTTATTGTCAGAATCT GTAGAAACTGGAGGTCTTTGTAAAGAAATAGACTAGTAGGATTGTGAGAATATATAGTGAGGGGGGATTTAGGATAAGGCTTCCTTGCTG GGATCCTTGGACAGAAACCTTACAATTGTTTAATATTTGCAGAGTAAAAGAGCAGCTATTGCTATTTGAACCTACAGAAGAGACCTAAGA CGAGCGTCTCTGTAATCTAAATTTATATGATAATGTTGTCCCAGACCCAAAGGCACACCTATTCTCAGTAACTTAGAGAAGTCTTGGAAG TTGCTTCTGAATTACAGTAAAGAAATTAAATGAAGTCTTTATCCTTAAATAGGGCCAGGCATTGCTATCAACATAGTGTCTTTGGTTTTC CCCTTTAAATAGAAAACACCAAGCAGGGCCTTTCCAGACAATGTAGTCTTTCCTGTAAAGAAAATGGTTTTGGTGTGGGATTTGGTAAAA ACACTGGTTAGTTTGTAATGAAGAAAGAATTTTGGCATAGACAGTCCGACCCAGTTCATGGATACAGTTTGATCCCAGGGAGTTTAACAA AAGGAAGCTTTGGTTTTGCTAGCAACAGACTTGATCTTCTATAGTAATTAATTGCAATTAAGGTTTTCCAGGAGCTTTCTCATTTCTTAG CCCAGGGTCCAACCCCATTCCCTCTTTAAAAAAGAAAGAATAGGCCGGGAGCAGTGGCTCATGCCTGCAATCCCAGCACTTTGGGAGGCC AAGGCAGGTGGATCACAAGGTCAGGAGTTTGAGACCAGCGTGGCCAATATGGTGAAACCCTGTCTCTACTAAAAATACAAAATTAGCTAG GCGTGGTGGCAGGCGCCTGAGGCTGAGGCAGGAGAATCCTGCTAGTCTGAATTACAATAAGGAAATTAAATGAAGGATTTATCTTTAATA GAGCCAGGCATTGCTATCAACATAACATGTTTGGTTTTCCCCTTTAAATAGAAAACACCAAGCAGGGCCTTTCCAGACAAGGTAGTCTGG AACCCAGGAGGCGGAGGTTGCAGTGAGCCGAGATCCCACCATTGCACTCCAGCCTGGGTGGCAGAGTGAGACTCCGTCTCAAAAAAAAAA AAAAGAAGGAATAGGAAAAGGACTTAGAGGCAGTTGATATAGAATTCTACTGGGGGTAAATGACACTCTCAAAATACTTGGGAAAGAAGA ATCACATGCCACAAGCTATAGCTTGATTAATATTTTAGCATGTTTTCCATGTTTGTATTCTAAAGTTTGTTTCCTTTGACATTCCATTAT CTTACTTACTAGAGTGCCACCATTCTTATTTGTAATACAATCAGTGTTTTATGCCATTTGTGAATCACACAATTGTTCTTTTTTCCCCAT CACACACACTCACACACAAACACACACACTGTTAAAAATAAAAGAGGGGAAGGATAAAACAAAAATAGATAGAATGATGATTATTACAAT GTAACTTTAACATATATGAAGAGAAATTCTAACTCAGTTAAGTGAGAATTAAGATTGAAAGTATTAATGTTGCAAGTATTATCTCTAGCC ATGGAATTTTTTGCTGGCTATAGAATGCTAATGTGAACAGAGTATATATCAGGAATATGATGTATTATGGCACAGTGATAATATTATTGT TGATATTAGCCAGATGTGGTGGTTTGCACCTGTAGTCCGAACTTCTCAGGAGGATGAGGCAGGAGGATAGTTGAGCCCAGGAGTTTAAAG CAAGCCTGGGCAATACAGCAAGACCCCAATCTTTAAAATAAATAAATAAATAAGAATTATTCTTGAAAGTAATATTCTAACCTTCTGCCA ACCAACAGAGATCCTCATATTCTTAAAGAAAATTAATATAGCTTATGGTTTTGATAAATTGGACTCTGATTTAAACTTTAAAATGTTATG ACTTTTATTCTGATACATGGCTTCTAAAATATGTAAAAAATTATATTGAATGAATTAATACTTAACCTGTTCATTTCTCTTAATTTATGT ATTTATTCTGACTTTATTATACAGCTTATGTCTCACATCTGCCTTCTTGATATGTGCAAAATATTGTGTAAAAATAGTTTAAAACTCATC CCAGTTCCTAGTCAAGCGTGGGCTATAAGAGAGAAGGCTTAAGGTGTTCTTTAATGGAGGAACTTTTGAAAGATCACAAATGGAAAAAGC CTATTGAGAATTTATTGCCTTTGAGAGTAGAAAGGGCTCTAGAATATGAGCCAGAGACTTGGAATTTAGTAATAGGTCTCCCACTGATTT GCTCCGTGTCCTTAGGCAATTCGTTTAATCTCTGTGTGCCTAGTTTCCCCTTGTAAATAAGAGTGGTAATACCTGTCCTCACCTACCTCA CTAAATTGTTGGAGTTCTTTTGTTCTGAGTCAGGGTCTCACTCTGTTGCCCAGGCTGAACTACAGTAGTGTGATCATAGCTCACTACAGC CTCCAACTCCTGGGCCCAAACTATCCTCCTGCTTCAGCCTCCCAAGTAGCTGGGACTAGAGGTACATGCCACCACACCCAGCTAATTATT TTCTTTTATTGCAGAGATGGGGTCTCACATGTTGCCAAGGCTGATCTCTAACTCCTGAGCTCAAGCAGTCCTCCTGCCTCAGCCACCCAA AGTGCTGGGATTATAGGCATGATCACTAAATTGTTGTAAGAATAAGATAATGTTTGCGGAAGCATTTGAGTTCTCCAAAGGAAAAGCTAT TCAGACGTTCAAGATAATAGAAGAGTGTTGTGTGAAGGATTCCTTTCCAGTTTGCCTCTGTGAAAATGTCTTTGTTGTAGATCATTTTAT GAAATAGGAATAAGAGAAACATAGGCCTTATCATGGTGTAGTGTTCACTTACAAACATATCCTGTTGTTTCTTCCCTGCAAGATATCCAG CACACAGGCTGAATTTTTCTTTATAATAATCCTTGGCAAAAGCATAACTTTTCAAAAACCAAATGATTTTAGTGGTGCTATGGCAGCTGC AGTTTTGAGTTAGATTAATGTGGTGAAAACCATCAAATACTTAGAAATTGACTGGGTGCGGTGGCTCATGCCTGTAATCCCAGCACTTTG GGAGGCCGAGGTAGGTGGATCACTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGCAAAACCCCGTCTCTACTAAAGATACAAA AATTAGCTGGGCACGATGGAGGGTGCCTGTAATCCCAGCTACTCGGGAGGCTAAGGTGGGAGAATTGCTTGGACCCAGGTGGCAGAGGTT GCAGTGAGCCAAGATTGTGCCACTGCACTCCAGCCTGGGCAACAAAGCGAAGCTCTGTCTCAATAAAAAAAAAAATAATAATAATAAAAT ACAAATACTTAGAAATTAACTTCGCCTTTGCCTTCAGGCACTTTTGCTACATGTTAGCATCAGAGGCTATTGTACAACTAGATGGTTATT CCCTGTTTCTTGGCCGATTTTTGGTACCTTTCTTTGAAGAAGAGGGTTAGATTTTAAGAAAGAAAGTGTGCTTATTTCACTCATGTCTTT GCAGAATTTAACTTTGCTTTACTTTAAAAATTCCAATCATCATGTACCTATAAAGGTTAAAATATAGTGAAAGTTTCTGCTTCATGTGAA TTCAATTCTGAGCACCTGCAGGTCATATCAGGTGTCTGATGCAGTTACCTTTATAGATCGTGGCAGGTCCTTACATTTCAACAGGCTTAT GCATTTCCATGGGGGGAAGAGATTCTGTTTCTAGGAAATTACAAAGGGCACACCACTGCAGGGAGTGTAAACAATTCTTTGTTGCAACAG ACAAGATTTTTTTTAAAAAAAGAAAAAAGGATGCATTTTAGGTACACAGGGTATGGACGCATTCAACATTTACTTTTATCTCCACAGATG CCAACCTCCCCTTGTTGCAGGCAGTTGGGCTTTTCCAACTCATTGCTAACAAAGCTGGCATCTGCATTAATTTCAATGAGAATTTCAAGT ACTGAAGATGAAAAGTTGGGGAGATTCATGTTTGAAAAATGAAAAATGAACAAAAAATCCACCTTGTGCAGTGAGATAGCTAACGCTGAT ATATCAGGAATAATTTTAAACTATTTTTGCTGTAATGTGTAGCTTTAATGTCTCTTTTCAGTTATGGACCCATAAAAGTATTCCTATATC TTGTGAATAAAGATCATTCTTGTGGACTAGTACGTGGATGCATTCATAGGCTTTGGGAAGCAGTGGTGTGCGTATGTGTGTCTATATCAA TATTTTATGTTTATAACTCTGCGTATTAAGTTTATATAGAAAAAAATAATGTCTTTCTTTAGTGTTTGGGGGACTCAATGGTAATATGAC CATTGCAGTGTAATCTGACTGCTCACTCTAGAGAACACTTCTGTTATACACAATGCACATACAAACATACACCCCTAAAGCGTAGCTAAC TGCTCCCACTAGATAATTGCTGCTAAAAACAAAACAAAACAAAACAATACAAAACAAAAAAAACCCTAAGTAATGGAGGAAGAAATAGCA TTCTTTTAAAAGGGGCTTTTCTGAAGAGTAAAATGTAAATACAGGACATGTGGGGAGGGTGGGGCCGCCTGCAAAATGTCCTGAAGATGG ACAAATAGCCTTTTAAATTCTACTTTTTAACCATCTTTACCGTGTGTGCCTATTTGTATTGCAGATGTGAACTACTATTTTTGGAGGTTG ATATCAGTATGTTTTGAAACTGAATTATTACATAAAATCAGAGTAACCTCTTTCTCCATCCTCCTTTTCCACACTATTCTTGCCAAATAT TTCTACTGAAACCCAGTTTCAGCAAGGCAAAATGATGGGACTCTCAAACCTCCCTCCTCATCTTCCCTTCCCCTCTGTCTTATGCCTGGC CTGGCCTTTTTTGTTGTTGTTGGCTTTTCATAAGTAAGAAAAATTTATTGTAGTATTTCAAGACTGCAGAATTTCAAGTGTATATCTATA AATCTTTTTTTAAAATCTTCGGCTACACAGTAACATCAATTAAAACAGAAGAGTGAGTCTAAGTCTGTAATATGCTGTAGGACCAGATAA GATTTTGAATGAGACTAAACTTGACTGCCATATTTTAAGAGGAAATTGAAACTTTATGGTGGAGAATGGATGAGAGCAAGTCTATGATAT ATATGTAGTCATTGTATAATTAGAAACACCAAATGCTGAATCCTATCACTGTGTTCTTGGGGGCCAGGCCTTGGATTTGGTTGTCATTTA AACTCCTTGAAGATTATATGTAATTATAATGAGCAGAAGGCAAATAAAGTTTTTGAACAAAAGTCCTTGTTTTCAGTATTTAAAATTTGG TAATATATTTTCTTTTTCAGTTAAACTATCTTCCCCACAAAAAATATTATACTTCAGTTAAACTATCTTCCCCACAGAAATTATTATACT ACGAACAAGTTATGAGTGAGACTGAGAAGCTTGAAGAAGCTGGTTTTTAAGCAGCTCATATAATATTTTGTGTTAAAGAAAGTGTCATTG TTTCCTGTTGGGAGGCAAATAACAACAACAACAAAAGAAATTGTCATGATTCTTTCTGAGCCAAACTGTCACGAAATGTTCTGTGACAGA ACCACTACTCTTTTTTCTGCCATTCTGCCTACTGGAGAGTTCTATGTTGTATTTGTTTTTAATCCTTGATTTTAAAAATATTAATGGTTT >6279_6279_11_ARHGEF2-AGO3_ARHGEF2_chr1_155927504_ENST00000368315_AGO3_chr1_36432556_ENST00000373191_length(amino acids)=1369AA_BP=573 MCCCCGCCPLLAHLEQGSLRERTREKEKMKEAKDARYTNGHLFTTISVSGMTMCYACNKSITAKEALICPTCNVTIHNRCKDTLANCTKV KQKQQKAALLKNNTALQSVSLRSKTTIRERPSSAIYPSDSFRQSLLGSRRGRSSLSLAKSVSTTNIAGHFNDESPLGLRRILSQSTDSLN MRNRTLSVESLIDEAEVIYSELMSDFEMDEKDFAADSWSLAVDSSFLQQHKKEVMKQQDVIYELIQTELHHVRTLKIMTRLFRTGMLEEL HLEPGVVQGLFPCVDELSDIHTRFLSQLLERRRQALCPGSTRNFVIHRLGDLLISQFSGPSAEQMCKTYSEFCSRHSKALKLYKELYARD KRFQQFIRKVTRPAVLKRHGVQECILLVTQRITKYPLLISRILQHSHGIEEERQDLTTALGLVKELLSNVDEGIYQLEKGARLQEIYNRM DPRAQTPVPGKGPFGREELLRRKLIHDGCLLWKTATGRFKDVLVLLMTDVLVFLQEKDQKYIFPTLDKPSVVSLQNLIVRDIANQEKGMF LISAAPPEMYEVHTASRDDRSTWIRVIQQSVRTEVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPF KVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAM WKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLEN GQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYET DPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKD AGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVK LGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFK PTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYL CSHAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQ -------------------------------------------------------------- >6279_6279_12_ARHGEF2-AGO3_ARHGEF2_chr1_155927504_ENST00000368315_AGO3_chr1_36432556_ENST00000397828_length(transcript)=2586nt_BP=1718nt ATGTGCTGCTGCTGTGGCTGCTGCCCGCTGCTGGCCCACCTAGAGCAGGGGTCACTTCGAGAGAGGACCCGGGAAAAGGAGAAGATGAAG GAAGCCAAGGATGCCCGCTATACCAATGGGCACCTCTTCACCACCATTTCAGTTTCAGGCATGACCATGTGCTATGCCTGTAACAAGAGC ATCACAGCCAAGGAAGCCCTCATCTGCCCAACCTGCAATGTGACTATCCACAACCGCTGTAAAGACACCCTCGCCAACTGTACCAAGGTC AAGCAGAAGCAACAGAAAGCGGCCCTGCTGAAGAACAACACCGCCTTGCAGTCCGTTTCTCTTCGAAGTAAGACAACCATCCGGGAGCGG CCAAGCTCGGCCATCTACCCCTCCGACAGCTTCCGGCAGTCCCTCCTGGGCTCCCGCCGTGGCCGCTCCTCCTTGTCTTTAGCCAAGAGT GTTTCTACCACCAACATTGCTGGACATTTCAATGATGAGTCTCCCCTGGGGCTGCGCCGGATCCTCTCACAGTCCACAGACTCCCTCAAC ATGCGGAACCGAACCCTATCCGTGGAATCCCTCATTGACGAAGCAGAGGTAATCTACAGTGAGCTGATGAGTGACTTTGAGATGGATGAG AAGGACTTTGCAGCTGACTCTTGGAGTCTTGCTGTGGACAGCAGCTTCCTGCAGCAGCATAAAAAGGAGGTGATGAAGCAGCAAGATGTC ATCTATGAGCTAATCCAGACAGAGCTGCACCATGTGAGGACACTGAAGATCATGACCCGCCTCTTCCGCACGGGGATGCTGGAAGAGCTA CACTTGGAGCCAGGAGTGGTCCAGGGCCTGTTCCCCTGCGTGGACGAGCTCAGTGACATCCATACACGCTTCCTCAGCCAGCTATTAGAA CGCCGACGCCAGGCCCTGTGCCCTGGCAGCACCCGGAACTTTGTCATCCATCGCTTGGGTGATCTGCTCATCAGCCAGTTCTCAGGTCCT AGTGCGGAGCAGATGTGTAAGACCTACTCGGAGTTCTGCAGCCGCCACAGCAAGGCCTTAAAGCTCTATAAGGAGCTGTACGCCCGAGAC AAACGCTTCCAGCAATTCATCCGGAAAGTGACCCGCCCCGCCGTGCTCAAGCGGCACGGGGTACAGGAGTGCATCCTGCTGGTGACTCAG CGCATCACCAAGTACCCGTTACTCATCAGCCGCATCCTGCAGCATTCCCACGGGATCGAGGAGGAGCGCCAGGACCTGACCACAGCACTG GGGCTAGTGAAGGAGCTGCTGTCCAATGTGGACGAGGGTATTTATCAGCTGGAGAAAGGGGCCCGTCTGCAGGAGATCTACAACCGCATG GACCCTCGGGCCCAAACCCCAGTGCCTGGCAAGGGCCCCTTTGGCCGAGAGGAACTTCTGAGGCGCAAACTCATCCACGATGGCTGCCTG CTCTGGAAGACAGCGACGGGGCGCTTCAAAGATGTGCTAGTGCTGCTGATGACAGATGTACTGGTGTTTCTCCAGGAAAAGGACCAGAAG TACATCTTTCCTACCCTGGACAAGCCTTCAGTGGTATCGCTGCAGAATCTAATCGTACGAGACATTGCCAACCAGGAGAAAGGGATGTTT CTGATCAGCGCAGCCCCACCTGAGATGTACGAGGTGCACACAGCATCCCGGGATGACCGGAGCACCTGGATCCGGGTCATTCAGCAGAGC GTGCGCACGGAGGTGGTTGACTCAATGGTTCAGCATTTTAAAGTAACTATATTTGGAGACCGTAGACCAGTTTATGATGGAAAAAGAAGT CTTTACACCGCCAATCCACTTCCTGTGGCAACTACAGGGGTAGATTTAGACGTTACTTTACCTGGGGAAGGTGGAAAAGATCGACCTTTC AAGGTGTCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACGGACCTTGCCTGAGCCACTGGAATTA GACAAGCCAATCAGCACTAACCCTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCATGAAATACACACCTGTGGGGCGTTCA TTTTTCTCCGCTCCAGAAGGATATGACCACCCTCTGGGAGGGGGCAGGGAAGTGTGGTTTGGATTCCATCAGTCTGTTCGGCCTGCCATG TGGAAAATGATGCTTAATATCGATGAAAGAGACCTCTGGCAGCAGTGTGGAGAATAGATAGAGGAGAAAAAACTAATCTGAGAAGCCAGT TAGGAGGCTTTTCAATCACTAGTTCAGGTTTCAGTCTACATGTTACTTCCTTGAGAAGCAGTGTTTGACACCCTTCTCCCCCAATCCAGC CATCCCCCAAGTCTGAGTTAGGTATTTCTCTTCTGTATTCCCATAGCACAGTGTAATTCCCCTATAATAGCATGTATCACCTTGAATTAT GGGTGTTTATTGTTCTGTCTCTCCTGTTAGAACGAAAGCTCCATGAAGGGATTGTCATTTTATTCACCAGTGTACCCTCTATGCCCAGCA >6279_6279_12_ARHGEF2-AGO3_ARHGEF2_chr1_155927504_ENST00000368315_AGO3_chr1_36432556_ENST00000397828_length(amino acids)=738AA_BP=573 MCCCCGCCPLLAHLEQGSLRERTREKEKMKEAKDARYTNGHLFTTISVSGMTMCYACNKSITAKEALICPTCNVTIHNRCKDTLANCTKV KQKQQKAALLKNNTALQSVSLRSKTTIRERPSSAIYPSDSFRQSLLGSRRGRSSLSLAKSVSTTNIAGHFNDESPLGLRRILSQSTDSLN MRNRTLSVESLIDEAEVIYSELMSDFEMDEKDFAADSWSLAVDSSFLQQHKKEVMKQQDVIYELIQTELHHVRTLKIMTRLFRTGMLEEL HLEPGVVQGLFPCVDELSDIHTRFLSQLLERRRQALCPGSTRNFVIHRLGDLLISQFSGPSAEQMCKTYSEFCSRHSKALKLYKELYARD KRFQQFIRKVTRPAVLKRHGVQECILLVTQRITKYPLLISRILQHSHGIEEERQDLTTALGLVKELLSNVDEGIYQLEKGARLQEIYNRM DPRAQTPVPGKGPFGREELLRRKLIHDGCLLWKTATGRFKDVLVLLMTDVLVFLQEKDQKYIFPTLDKPSVVSLQNLIVRDIANQEKGMF LISAAPPEMYEVHTASRDDRSTWIRVIQQSVRTEVVDSMVQHFKVTIFGDRRPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPF KVSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPISTNPVHAVDVVLRHLPSMKYTPVGRSFFSAPEGYDHPLGGGREVWFGFHQSVRPAM -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for ARHGEF2-EIF2C3 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| Hgene | ARHGEF2 | chr1:155927504 | chr1:36432556 | ENST00000313667 | - | 13 | 22 | 131_161 | 570.6666666666666 | 986.0 | DYNLT1 |
| Hgene | ARHGEF2 | chr1:155927504 | chr1:36432556 | ENST00000313695 | - | 13 | 22 | 131_161 | 543.6666666666666 | 959.0 | DYNLT1 |
| Hgene | ARHGEF2 | chr1:155927504 | chr1:36432556 | ENST00000361247 | - | 13 | 22 | 131_161 | 571.6666666666666 | 987.0 | DYNLT1 |
| Hgene | ARHGEF2 | chr1:155927504 | chr1:36432556 | ENST00000368316 | - | 17 | 26 | 131_161 | 543.6666666666666 | 959.0 | DYNLT1 |
| Tgene | AGO3 | chr1:155927504 | chr1:36432556 | ENST00000246314 | 0 | 17 | 530_567 | 0 | 627.0 | guide RNA | |
| Tgene | AGO3 | chr1:155927504 | chr1:36432556 | ENST00000246314 | 0 | 17 | 758_805 | 0 | 627.0 | guide RNA | |
| Tgene | AGO3 | chr1:155927504 | chr1:36432556 | ENST00000373191 | 1 | 19 | 530_567 | 63.666666666666664 | 861.0 | guide RNA | |
| Tgene | AGO3 | chr1:155927504 | chr1:36432556 | ENST00000373191 | 1 | 19 | 758_805 | 63.666666666666664 | 861.0 | guide RNA |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for ARHGEF2-EIF2C3 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for ARHGEF2-EIF2C3 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | ARHGEF2 | C4479613 | NEURODEVELOPMENTAL DISORDER WITH MIDBRAIN AND HINDBRAIN MALFORMATIONS | 1 | GENOMICS_ENGLAND |
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