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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CD9-ADAMTS12 (FusionGDB2 ID:HG928TG81792)

Fusion Gene Summary for CD9-ADAMTS12

check button Fusion gene summary
Fusion gene informationFusion gene name: CD9-ADAMTS12
Fusion gene ID: hg928tg81792
HgeneTgene
Gene symbol

CD9

ADAMTS12

Gene ID

928

81792

Gene nameCD9 moleculeADAM metallopeptidase with thrombospondin type 1 motif 12
SynonymsBTCC-1|DRAP-27|MIC3|MRP-1|TSPAN-29|TSPAN29PRO4389
Cytomap('CD9')('ADAMTS12')

12p13.31

5p13.3-p13.2

Type of geneprotein-codingprotein-coding
DescriptionCD9 antigen5H9 antigenBA-2/p24 antigenCD9 antigen (p24)antigen CD9cell growth-inhibiting gene 2 proteinleukocyte antigen MIC3motility related protein-1tetraspanin-29A disintegrin and metalloproteinase with thrombospondin motifs 12ADAM-TS 12ADAM-TS12ADAMTS-12a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 12
Modification date2020032720200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000481267, ENST00000009180, 
ENST00000382518, ENST00000382515, 
Fusion gene scores* DoF score13 X 11 X 7=10019 X 7 X 7=441
# samples 149
** MAII scorelog2(14/1001*10)=-2.83794324189103
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/441*10)=-2.29278174922785
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CD9 [Title/Abstract] AND ADAMTS12 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCD9(6334700)-ADAMTS12(33684160), # samples:2
Anticipated loss of major functional domain due to fusion event.CD9-ADAMTS12 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CD9-ADAMTS12 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
CD9-ADAMTS12 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
CD9-ADAMTS12 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCD9

GO:0007155

cell adhesion

7511626

HgeneCD9

GO:0007342

fusion of sperm to egg plasma membrane involved in single fertilization

14575715

HgeneCD9

GO:0051271

negative regulation of cellular component movement

8478605

HgeneCD9

GO:0090331

negative regulation of platelet aggregation

18541721

TgeneADAMTS12

GO:0030167

proteoglycan catabolic process

17895370

TgeneADAMTS12

GO:0032331

negative regulation of chondrocyte differentiation

22247065

TgeneADAMTS12

GO:0050727

regulation of inflammatory response

23019333

TgeneADAMTS12

GO:0051603

proteolysis involved in cellular protein catabolic process

16611630

TgeneADAMTS12

GO:0071773

cellular response to BMP stimulus

22247065

TgeneADAMTS12

GO:1901509

regulation of endothelial tube morphogenesis

17895370

TgeneADAMTS12

GO:1902203

negative regulation of hepatocyte growth factor receptor signaling pathway

17895370

TgeneADAMTS12

GO:1902548

negative regulation of cellular response to vascular endothelial growth factor stimulus

17895370

TgeneADAMTS12

GO:2001113

negative regulation of cellular response to hepatocyte growth factor stimulus

17895370


check buttonFusion gene breakpoints across CD9 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across ADAMTS12 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A7-A4SD-01ACD9chr12

6334699

+ADAMTS12chr5

33729891

-
ChimerDB4BRCATCGA-A7-A4SD-01ACD9chr12

6334700

+ADAMTS12chr5

33684160

-


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Fusion Gene ORF analysis for CD9-ADAMTS12

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000481267ENST00000352040CD9chr12

6334700

+ADAMTS12chr5

33684160

-
3UTR-3CDSENST00000481267ENST00000504830CD9chr12

6334700

+ADAMTS12chr5

33684160

-
3UTR-5UTRENST00000481267ENST00000504582CD9chr12

6334700

+ADAMTS12chr5

33684160

-
3UTR-intronENST00000481267ENST00000352040CD9chr12

6334699

+ADAMTS12chr5

33729891

-
3UTR-intronENST00000481267ENST00000504582CD9chr12

6334699

+ADAMTS12chr5

33729891

-
3UTR-intronENST00000481267ENST00000504830CD9chr12

6334699

+ADAMTS12chr5

33729891

-
3UTR-intronENST00000481267ENST00000515401CD9chr12

6334699

+ADAMTS12chr5

33729891

-
3UTR-intronENST00000481267ENST00000515401CD9chr12

6334700

+ADAMTS12chr5

33684160

-
5CDS-5UTRENST00000009180ENST00000504582CD9chr12

6334700

+ADAMTS12chr5

33684160

-
5CDS-5UTRENST00000382518ENST00000504582CD9chr12

6334700

+ADAMTS12chr5

33684160

-
5CDS-intronENST00000009180ENST00000352040CD9chr12

6334699

+ADAMTS12chr5

33729891

-
5CDS-intronENST00000009180ENST00000504582CD9chr12

6334699

+ADAMTS12chr5

33729891

-
5CDS-intronENST00000009180ENST00000504830CD9chr12

6334699

+ADAMTS12chr5

33729891

-
5CDS-intronENST00000009180ENST00000515401CD9chr12

6334699

+ADAMTS12chr5

33729891

-
5CDS-intronENST00000009180ENST00000515401CD9chr12

6334700

+ADAMTS12chr5

33684160

-
5CDS-intronENST00000382518ENST00000352040CD9chr12

6334699

+ADAMTS12chr5

33729891

-
5CDS-intronENST00000382518ENST00000504582CD9chr12

6334699

+ADAMTS12chr5

33729891

-
5CDS-intronENST00000382518ENST00000504830CD9chr12

6334699

+ADAMTS12chr5

33729891

-
5CDS-intronENST00000382518ENST00000515401CD9chr12

6334699

+ADAMTS12chr5

33729891

-
5CDS-intronENST00000382518ENST00000515401CD9chr12

6334700

+ADAMTS12chr5

33684160

-
5UTR-3CDSENST00000382515ENST00000352040CD9chr12

6334700

+ADAMTS12chr5

33684160

-
5UTR-3CDSENST00000382515ENST00000504830CD9chr12

6334700

+ADAMTS12chr5

33684160

-
5UTR-5UTRENST00000382515ENST00000504582CD9chr12

6334700

+ADAMTS12chr5

33684160

-
5UTR-intronENST00000382515ENST00000352040CD9chr12

6334699

+ADAMTS12chr5

33729891

-
5UTR-intronENST00000382515ENST00000504582CD9chr12

6334699

+ADAMTS12chr5

33729891

-
5UTR-intronENST00000382515ENST00000504830CD9chr12

6334699

+ADAMTS12chr5

33729891

-
5UTR-intronENST00000382515ENST00000515401CD9chr12

6334699

+ADAMTS12chr5

33729891

-
5UTR-intronENST00000382515ENST00000515401CD9chr12

6334700

+ADAMTS12chr5

33684160

-
In-frameENST00000009180ENST00000352040CD9chr12

6334700

+ADAMTS12chr5

33684160

-
In-frameENST00000009180ENST00000504830CD9chr12

6334700

+ADAMTS12chr5

33684160

-
In-frameENST00000382518ENST00000352040CD9chr12

6334700

+ADAMTS12chr5

33684160

-
In-frameENST00000382518ENST00000504830CD9chr12

6334700

+ADAMTS12chr5

33684160

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000382518CD9chr126334700+ENST00000504830ADAMTS12chr533684160-841561124747611504
ENST00000382518CD9chr126334700+ENST00000352040ADAMTS12chr533684160-451461124745061419
ENST00000009180CD9chr126334700+ENST00000504830ADAMTS12chr533684160-80302265143761441
ENST00000009180CD9chr126334700+ENST00000352040ADAMTS12chr533684160-41292265141211356

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000382518ENST00000504830CD9chr126334700+ADAMTS12chr533684160-0.0004108290.99958915
ENST00000382518ENST00000352040CD9chr126334700+ADAMTS12chr533684160-0.0014378470.99856216
ENST00000009180ENST00000504830CD9chr126334700+ADAMTS12chr533684160-0.0002614110.99973863
ENST00000009180ENST00000352040CD9chr126334700+ADAMTS12chr533684160-0.0009991320.99900085

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Fusion Genomic Features for CD9-ADAMTS12


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

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Fusion Protein Features for CD9-ADAMTS12


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:6334700/chr5:33684160)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCD9chr12:6334700chr5:33684160ENST00000009180+282_1258229.0Topological domainCytoplasmic
HgeneCD9chr12:6334700chr5:33684160ENST00000009180+2834_5558229.0Topological domainExtracellular
HgeneCD9chr12:6334700chr5:33684160ENST00000382518+392_1258229.0Topological domainCytoplasmic
HgeneCD9chr12:6334700chr5:33684160ENST00000382518+3934_5558229.0Topological domainExtracellular
HgeneCD9chr12:6334700chr5:33684160ENST00000009180+2813_3358229.0TransmembraneHelical
HgeneCD9chr12:6334700chr5:33684160ENST00000382518+3913_3358229.0TransmembraneHelical
TgeneADAMTS12chr12:6334700chr5:33684160ENST00000352040222302_3052111510.0Compositional biasNote=Poly-Glu
TgeneADAMTS12chr12:6334700chr5:33684160ENST00000352040222597_7002111510.0Compositional biasNote=Cys-rich
TgeneADAMTS12chr12:6334700chr5:33684160ENST00000504830224302_3052111595.0Compositional biasNote=Poly-Glu
TgeneADAMTS12chr12:6334700chr5:33684160ENST00000504830224597_7002111595.0Compositional biasNote=Cys-rich
TgeneADAMTS12chr12:6334700chr5:33684160ENST000003520402221313_13662111510.0DomainTSP type-1 5
TgeneADAMTS12chr12:6334700chr5:33684160ENST000003520402221368_14222111510.0DomainTSP type-1 6
TgeneADAMTS12chr12:6334700chr5:33684160ENST000003520402221423_14712111510.0DomainTSP type-1 7
TgeneADAMTS12chr12:6334700chr5:33684160ENST000003520402221472_15322111510.0DomainTSP type-1 8
TgeneADAMTS12chr12:6334700chr5:33684160ENST000003520402221535_15752111510.0DomainPLAC
TgeneADAMTS12chr12:6334700chr5:33684160ENST00000352040222246_4562111510.0DomainPeptidase M12B
TgeneADAMTS12chr12:6334700chr5:33684160ENST00000352040222465_5442111510.0DomainNote=Disintegrin
TgeneADAMTS12chr12:6334700chr5:33684160ENST00000352040222542_5972111510.0DomainTSP type-1 1
TgeneADAMTS12chr12:6334700chr5:33684160ENST00000352040222823_8832111510.0DomainTSP type-1 2
TgeneADAMTS12chr12:6334700chr5:33684160ENST00000352040222887_9432111510.0DomainTSP type-1 3
TgeneADAMTS12chr12:6334700chr5:33684160ENST00000352040222944_9972111510.0DomainTSP type-1 4
TgeneADAMTS12chr12:6334700chr5:33684160ENST000005048302241313_13662111595.0DomainTSP type-1 5
TgeneADAMTS12chr12:6334700chr5:33684160ENST000005048302241368_14222111595.0DomainTSP type-1 6
TgeneADAMTS12chr12:6334700chr5:33684160ENST000005048302241423_14712111595.0DomainTSP type-1 7
TgeneADAMTS12chr12:6334700chr5:33684160ENST000005048302241472_15322111595.0DomainTSP type-1 8
TgeneADAMTS12chr12:6334700chr5:33684160ENST000005048302241535_15752111595.0DomainPLAC
TgeneADAMTS12chr12:6334700chr5:33684160ENST00000504830224246_4562111595.0DomainPeptidase M12B
TgeneADAMTS12chr12:6334700chr5:33684160ENST00000504830224465_5442111595.0DomainNote=Disintegrin
TgeneADAMTS12chr12:6334700chr5:33684160ENST00000504830224542_5972111595.0DomainTSP type-1 1
TgeneADAMTS12chr12:6334700chr5:33684160ENST00000504830224823_8832111595.0DomainTSP type-1 2
TgeneADAMTS12chr12:6334700chr5:33684160ENST00000504830224887_9432111595.0DomainTSP type-1 3
TgeneADAMTS12chr12:6334700chr5:33684160ENST00000504830224944_9972111595.0DomainTSP type-1 4
TgeneADAMTS12chr12:6334700chr5:33684160ENST00000352040222701_8272111510.0RegionNote=Spacer 1
TgeneADAMTS12chr12:6334700chr5:33684160ENST00000352040222997_13162111510.0RegionNote=Spacer 2
TgeneADAMTS12chr12:6334700chr5:33684160ENST00000504830224701_8272111595.0RegionNote=Spacer 1
TgeneADAMTS12chr12:6334700chr5:33684160ENST00000504830224997_13162111595.0RegionNote=Spacer 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCD9chr12:6334700chr5:33684160ENST00000009180+28112_19558229.0Topological domainExtracellular
HgeneCD9chr12:6334700chr5:33684160ENST00000009180+28222_22858229.0Topological domainCytoplasmic
HgeneCD9chr12:6334700chr5:33684160ENST00000009180+2877_8758229.0Topological domainCytoplasmic
HgeneCD9chr12:6334700chr5:33684160ENST00000382518+39112_19558229.0Topological domainExtracellular
HgeneCD9chr12:6334700chr5:33684160ENST00000382518+39222_22858229.0Topological domainCytoplasmic
HgeneCD9chr12:6334700chr5:33684160ENST00000382518+3977_8758229.0Topological domainCytoplasmic
HgeneCD9chr12:6334700chr5:33684160ENST00000009180+28196_22158229.0TransmembraneHelical
HgeneCD9chr12:6334700chr5:33684160ENST00000009180+2856_7658229.0TransmembraneHelical
HgeneCD9chr12:6334700chr5:33684160ENST00000009180+2888_11158229.0TransmembraneHelical
HgeneCD9chr12:6334700chr5:33684160ENST00000382518+39196_22158229.0TransmembraneHelical
HgeneCD9chr12:6334700chr5:33684160ENST00000382518+3956_7658229.0TransmembraneHelical
HgeneCD9chr12:6334700chr5:33684160ENST00000382518+3988_11158229.0TransmembraneHelical
TgeneADAMTS12chr12:6334700chr5:33684160ENST00000352040222208_2132111510.0MotifCysteine switch
TgeneADAMTS12chr12:6334700chr5:33684160ENST00000504830224208_2132111595.0MotifCysteine switch


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Fusion Gene Sequence for CD9-ADAMTS12


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>14742_14742_1_CD9-ADAMTS12_CD9_chr12_6334700_ENST00000009180_ADAMTS12_chr5_33684160_ENST00000352040_length(transcript)=4129nt_BP=226nt
CGCGCCCCCCAGTCCCGCACCCGTTCGGCCCAGGCTAAGTTAGCCCTCACCATGCCGGTCAAAGGAGGCACCAAGTGCATCAAATACCTG
CTGTTCGGATTTAACTTCATCTTCTGGCTTGCCGGGATTGCTGTCCTTGCCATTGGACTATGGCTCCGATTCGACTCTCAGACCAAGAGC
ATCTTCGAGCAAGAAACTAATAATAATAATTCCAGCTTCTACACAGACAGTGTTAACATCTCCCAGAAGCAAGAGCTATGGCGGGAGAAG
TGGGAGAGGCACAACTTGCCAAGCAGAAGCCTCTCTCGGCGTTCCATCAGCAAGGAGAGATGGGTGGAGACACTGGTGGTGGCCGACACA
AAGATGATTGAATACCATGGGAGTGAGAATGTGGAGTCCTACATCCTCACCATCATGAACATGGTCACTGGGTTGTTCCATAACCCAAGC
ATTGGCAATGCAATTCACATTGTTGTGGTTCGGCTCATTCTACTCGAAGAAGAAGAGCAAGGACTGAAAATAGTTCACCATGCAGAAAAG
ACACTGTCTAGCTTCTGCAAGTGGCAGAAGAGTATCAATCCCAAGAGTGACCTCAATCCTGTTCATCACGACGTGGCTGTCCTTCTCACC
AGAAAGGACATCTGTGCTGGTTTCAATCGCCCCTGCGAGACCCTGGGCCTGTCTCACCTTTCAGGAATGTGTCAGCCTCACCGCAGTTGT
AACATCAATGAAGATTCGGGACTCCCTCTGGCTTTCACAATTGCCCATGAGCTAGGACACAGCTTCGGCATCCAGCATGATGGGAAAGAA
AATGACTGTGAGCCTGTGGGCAGACATCCGTACATCATGTCCCGCCAGCTCCAGTACGATCCCACTCCGCTGACATGGTCCAAGTGCAGC
GAGGAGTACATCACCCGCTTCTTGGACCGAGGCTGGGGGTTCTGTCTTGATGACATACCTAAAAAGAAAGGCTTGAAGTCCAAGGTCATT
GCCCCCGGAGTGATCTATGATGTTCACCACCAGTGCCAGCTACAATATGGACCCAATGCTACCTTCTGCCAGGAAGTAGAAAACGTCTGC
CAGACACTGTGGTGCTCCGTGAAGGGCTTTTGTCGCTCTAAGCTGGACGCTGCTGCAGATGGAACTCAATGTGGTGAGAAGAAGTGGTGT
ATGGCAGGCAAGTGCATCACAGTGGGGAAGAAACCAGAGAGCATTCCTGGAGGCTGGGGCCGCTGGTCACCCTGGTCCCACTGTTCCAGG
ACCTGTGGGGCTGGAGTCCAGAGCGCAGAGAGGCTCTGCAACAACCCCGAGCCAAAGTTTGGAGGGAAATATTGCACTGGAGAAAGAAAA
CGCTATCGCTTGTGCAACGTCCACCCCTGTCGCTCAGAGGCACCAACATTTCGGCAGATGCAGTGCAGTGAATTTGACACTGTTCCCTAC
AAGAATGAACTCTACCACTGGTTTCCCATTTTTAACCCAGGTTATGTTGACATTGGGCTCATTCCAAAAGGAGCAAGGGACATAAGAGTG
ATGGAAATTGAGGGAGCTGGAAACTTCCTGGCCATCAGGAGTGAAGATCCTGAAAAATATTACCTGAATGGAGGGTTTATTATCCAGTGG
AACGGGAACTATAAGCTGGCAGGGACTGTCTTTCAGTATGACAGGAAAGGAGACCTGGAAAAGCTGATGGCCACAGGTCCCACCAATGAG
TCTGTGTGGATCCAGCTTCTATTCCAGGTGACTAACCCTGGCATCAAGTATGAGTACACAATCCAGAAAGATGGCCTTGACAATGATGTT
GAGCAGCAGATGTACTTCTGGCAGTACGGCCACTGGACAGAGTGCAGTGTGACCTGCGGGACAGGTATCCGCCGCCAAACTGCCCATTGC
ATAAAGAAGGGCCGCGGGATGGTGAAAGCTACATTCTGTGACCCAGAAACACAGCCCAATGGGAGACAGAAGAAGTGCCATGAAAAGGCT
TGTCCACCCAGGTGGTGGGCAGGGGAGTGGGAAGCATGCTCGGCGACATGCGGGCCCCACGGGGAGAAGAAGCGAACCGTGCTGTGCATC
CAGACCATGGTCTCTGACGAGCAGGCTCTCCCGCCCACAGACTGCCAGCACCTGCTGAAGCCCAAGACCCTCCTTTCCTGCAACAGAGAC
ATCCTGTGCCCCTCGGACTGGACAGTGGGCAACTGGAGTGAGTGTTCTGTTTCCTGTGGTGGTGGAGTGCGGATTCGCAGTGTCACATGT
GCCAAGAACCATGATGAACCTTGCGATGTGACAAGGAAACCCAACAGCCGAGCTCTGTGTGGCCTCCAGCAATGCCCTTCTAGCCGGAGA
GTTCTGAAACCAAACAAAGGCACTATTTCCAATGGAAAAAACCCACCAACACTAAAGCCCGTCCCTCCACCTACATCCAGGCCCAGAATG
CTGACCACACCCACAGGGCCTGAGTCTATGAGCACAAGCACTCCAGCAATCAGCAGCCCTAGTCCTACCACAGCCTCCAAAGAAGGAGAC
CTGGGTGGGAAACAGTGGCAAGATAGCTCAACCCAACCTGAGCTGAGCTCTCGCTATCTCATTTCCACTGGAAGCACTTCCCAGCCCATC
CTCACTTCCCAATCCTTGAGCATTCAGCCAAGTGAGGAAAATGTTTCCAGTTCAGATACTGGTCCTACCTCGGAGGGAGGCCTTGTAGCT
ACAACAACAAGTGGTTCTGGCTTGTCATCTTCCCGCAACCCTATCACTTGGCCTGTGACTCCATTTTACAATACCTTGACCAAAGGTCCA
GAAATGGAGATTCACAGTGGCTCAGGGGAAGAAAGAGAACAGCCTGAGGACAAAGATGAAAGCAATCCTGTAATATGGACCAAGATCAGA
GTACCTGGAAATGACGCTCCAGTGGAAAGTACAGAAATGCCACTTGCACCTCCACTAACACCAGATCTCAGCAGGGAGTCCTGGTGGCCA
CCCTTCAGCACAGTAATGGAAGGACTGCTCCCCAGCCAAAGGCCCACTACTTCCGAAACTGGGACACCCAGAGTTGAGGGGATGGTTACT
GAAAAGCCAGCCAACACTCTGCTCCCTCTGGGAGGAGACCACCAGCCAGAACCCTCAGGAAAGACGGCAAACCGTAACCACCTGAAACTT
CCAAACAACATGAACCAAACAAAAAGTTCTGAACCAGTCCTGACTGAGGAGGATGCAACAAGTCTGATTACTGAGGGCTTTTTGCTAAAT
GCCTCCAATTACAAGCAGCTCACAAACGGCCACGGCTCTGCACACTGGATCGTCGGAAACTGGAGCGAGTGCTCCACCACATGTGGCCTG
GGGGCCTACTGGAGAAGGGTGGAGTGCAGCACCCAGATGGATTCTGACTGTGCGGCCATCCAGAGACCTGACCCTGCAAAAAGATGCCAC
CTCCGTCCCTGTGCTGGCTGGAAAGTGGGAAACTGGAGCAAGTGCTCCAGAAACTGCAGTGGGGGCTTCAAGATACGCGAGATTCAGTGC
GTGGACAGCCGGGACCACCGGAACCTGAGGCCATTTCACTGCCAGTTCCTGGCCGGCATTCCTCCCCCATTGAGCATGAGCTGTAACCCG
GAGCCCTGTGAGGCGTGGCAGGTGGAGCCTTGGAGCCAGTGCTCCAGGTCCTGTGGAGGTGGAGTTCAGGAGAGAGGAGTGTTCTGTCCA
GGAGGCCTCTGTGATTGGACAAAAAGACCCACATCCACCATGTCTTGCAATGAGCACCTGTGCTGTCACTGGGCCACTGGGAACTGGGAC
CTGTGTTCCACTTCCTGTGGAGGTGGCTTTCAGAAGAGGACTGTCCAATGTGTGCCCTCAGAGGGCAATAAAACTGAAGACCAAGACCAA
TGTCTATGTGATCACAAACCCAGACCTCCAGAATTCAAAAAATGCAACCAGCAGGCCTGCAAGAAAAGTGCCGATTTACTTTGCACTAAG
GACAAACTGTCAGCCAGTTTCTGCCAGACACTGAAAGCCATGAAGAAATGTTCTGTGCCCACCGTGAGGGCTGAGTGCTGCTTCTCGTGT

>14742_14742_1_CD9-ADAMTS12_CD9_chr12_6334700_ENST00000009180_ADAMTS12_chr5_33684160_ENST00000352040_length(amino acids)=1356AA_BP=58
MPVKGGTKCIKYLLFGFNFIFWLAGIAVLAIGLWLRFDSQTKSIFEQETNNNNSSFYTDSVNISQKQELWREKWERHNLPSRSLSRRSIS
KERWVETLVVADTKMIEYHGSENVESYILTIMNMVTGLFHNPSIGNAIHIVVVRLILLEEEEQGLKIVHHAEKTLSSFCKWQKSINPKSD
LNPVHHDVAVLLTRKDICAGFNRPCETLGLSHLSGMCQPHRSCNINEDSGLPLAFTIAHELGHSFGIQHDGKENDCEPVGRHPYIMSRQL
QYDPTPLTWSKCSEEYITRFLDRGWGFCLDDIPKKKGLKSKVIAPGVIYDVHHQCQLQYGPNATFCQEVENVCQTLWCSVKGFCRSKLDA
AADGTQCGEKKWCMAGKCITVGKKPESIPGGWGRWSPWSHCSRTCGAGVQSAERLCNNPEPKFGGKYCTGERKRYRLCNVHPCRSEAPTF
RQMQCSEFDTVPYKNELYHWFPIFNPGYVDIGLIPKGARDIRVMEIEGAGNFLAIRSEDPEKYYLNGGFIIQWNGNYKLAGTVFQYDRKG
DLEKLMATGPTNESVWIQLLFQVTNPGIKYEYTIQKDGLDNDVEQQMYFWQYGHWTECSVTCGTGIRRQTAHCIKKGRGMVKATFCDPET
QPNGRQKKCHEKACPPRWWAGEWEACSATCGPHGEKKRTVLCIQTMVSDEQALPPTDCQHLLKPKTLLSCNRDILCPSDWTVGNWSECSV
SCGGGVRIRSVTCAKNHDEPCDVTRKPNSRALCGLQQCPSSRRVLKPNKGTISNGKNPPTLKPVPPPTSRPRMLTTPTGPESMSTSTPAI
SSPSPTTASKEGDLGGKQWQDSSTQPELSSRYLISTGSTSQPILTSQSLSIQPSEENVSSSDTGPTSEGGLVATTTSGSGLSSSRNPITW
PVTPFYNTLTKGPEMEIHSGSGEEREQPEDKDESNPVIWTKIRVPGNDAPVESTEMPLAPPLTPDLSRESWWPPFSTVMEGLLPSQRPTT
SETGTPRVEGMVTEKPANTLLPLGGDHQPEPSGKTANRNHLKLPNNMNQTKSSEPVLTEEDATSLITEGFLLNASNYKQLTNGHGSAHWI
VGNWSECSTTCGLGAYWRRVECSTQMDSDCAAIQRPDPAKRCHLRPCAGWKVGNWSKCSRNCSGGFKIREIQCVDSRDHRNLRPFHCQFL
AGIPPPLSMSCNPEPCEAWQVEPWSQCSRSCGGGVQERGVFCPGGLCDWTKRPTSTMSCNEHLCCHWATGNWDLCSTSCGGGFQKRTVQC
VPSEGNKTEDQDQCLCDHKPRPPEFKKCNQQACKKSADLLCTKDKLSASFCQTLKAMKKCSVPTVRAECCFSCPQTHITHTQRQRRQRLL

--------------------------------------------------------------
>14742_14742_2_CD9-ADAMTS12_CD9_chr12_6334700_ENST00000009180_ADAMTS12_chr5_33684160_ENST00000504830_length(transcript)=8030nt_BP=226nt
CGCGCCCCCCAGTCCCGCACCCGTTCGGCCCAGGCTAAGTTAGCCCTCACCATGCCGGTCAAAGGAGGCACCAAGTGCATCAAATACCTG
CTGTTCGGATTTAACTTCATCTTCTGGCTTGCCGGGATTGCTGTCCTTGCCATTGGACTATGGCTCCGATTCGACTCTCAGACCAAGAGC
ATCTTCGAGCAAGAAACTAATAATAATAATTCCAGCTTCTACACAGACAGTGTTAACATCTCCCAGAAGCAAGAGCTATGGCGGGAGAAG
TGGGAGAGGCACAACTTGCCAAGCAGAAGCCTCTCTCGGCGTTCCATCAGCAAGGAGAGATGGGTGGAGACACTGGTGGTGGCCGACACA
AAGATGATTGAATACCATGGGAGTGAGAATGTGGAGTCCTACATCCTCACCATCATGAACATGGTCACTGGGTTGTTCCATAACCCAAGC
ATTGGCAATGCAATTCACATTGTTGTGGTTCGGCTCATTCTACTCGAAGAAGAAGAGCAAGGACTGAAAATAGTTCACCATGCAGAAAAG
ACACTGTCTAGCTTCTGCAAGTGGCAGAAGAGTATCAATCCCAAGAGTGACCTCAATCCTGTTCATCACGACGTGGCTGTCCTTCTCACC
AGAAAGGACATCTGTGCTGGTTTCAATCGCCCCTGCGAGACCCTGGGCCTGTCTCACCTTTCAGGAATGTGTCAGCCTCACCGCAGTTGT
AACATCAATGAAGATTCGGGACTCCCTCTGGCTTTCACAATTGCCCATGAGCTAGGACACAGCTTCGGCATCCAGCATGATGGGAAAGAA
AATGACTGTGAGCCTGTGGGCAGACATCCGTACATCATGTCCCGCCAGCTCCAGTACGATCCCACTCCGCTGACATGGTCCAAGTGCAGC
GAGGAGTACATCACCCGCTTCTTGGACCGAGGCTGGGGGTTCTGTCTTGATGACATACCTAAAAAGAAAGGCTTGAAGTCCAAGGTCATT
GCCCCCGGAGTGATCTATGATGTTCACCACCAGTGCCAGCTACAATATGGACCCAATGCTACCTTCTGCCAGGAAGTAGAAAACGTCTGC
CAGACACTGTGGTGCTCCGTGAAGGGCTTTTGTCGCTCTAAGCTGGACGCTGCTGCAGATGGAACTCAATGTGGTGAGAAGAAGTGGTGT
ATGGCAGGCAAGTGCATCACAGTGGGGAAGAAACCAGAGAGCATTCCTGGAGGCTGGGGCCGCTGGTCACCCTGGTCCCACTGTTCCAGG
ACCTGTGGGGCTGGAGTCCAGAGCGCAGAGAGGCTCTGCAACAACCCCGAGCCAAAGTTTGGAGGGAAATATTGCACTGGAGAAAGAAAA
CGCTATCGCTTGTGCAACGTCCACCCCTGTCGCTCAGAGGCACCAACATTTCGGCAGATGCAGTGCAGTGAATTTGACACTGTTCCCTAC
AAGAATGAACTCTACCACTGGTTTCCCATTTTTAACCCAGCACATCCTTGTGAGCTCTACTGCCGACCCATAGATGGCCAGTTTTCTGAG
AAAATGCTGGATGCTGTCATTGATGGTACCCCTTGCTTTGAAGGCGGCAACAGCAGAAATGTCTGTATTAATGGCATATGTAAGATGGTT
GGCTGTGACTATGAGATCGATTCCAATGCCACCGAGGATCGCTGCGGTGTGTGCCTGGGAGATGGCTCTTCCTGCCAGACTGTGAGAAAG
ATGTTTAAGCAGAAGGAAGGATCTGGTTATGTTGACATTGGGCTCATTCCAAAAGGAGCAAGGGACATAAGAGTGATGGAAATTGAGGGA
GCTGGAAACTTCCTGGCCATCAGGAGTGAAGATCCTGAAAAATATTACCTGAATGGAGGGTTTATTATCCAGTGGAACGGGAACTATAAG
CTGGCAGGGACTGTCTTTCAGTATGACAGGAAAGGAGACCTGGAAAAGCTGATGGCCACAGGTCCCACCAATGAGTCTGTGTGGATCCAG
CTTCTATTCCAGGTGACTAACCCTGGCATCAAGTATGAGTACACAATCCAGAAAGATGGCCTTGACAATGATGTTGAGCAGCAGATGTAC
TTCTGGCAGTACGGCCACTGGACAGAGTGCAGTGTGACCTGCGGGACAGGTATCCGCCGCCAAACTGCCCATTGCATAAAGAAGGGCCGC
GGGATGGTGAAAGCTACATTCTGTGACCCAGAAACACAGCCCAATGGGAGACAGAAGAAGTGCCATGAAAAGGCTTGTCCACCCAGGTGG
TGGGCAGGGGAGTGGGAAGCATGCTCGGCGACATGCGGGCCCCACGGGGAGAAGAAGCGAACCGTGCTGTGCATCCAGACCATGGTCTCT
GACGAGCAGGCTCTCCCGCCCACAGACTGCCAGCACCTGCTGAAGCCCAAGACCCTCCTTTCCTGCAACAGAGACATCCTGTGCCCCTCG
GACTGGACAGTGGGCAACTGGAGTGAGTGTTCTGTTTCCTGTGGTGGTGGAGTGCGGATTCGCAGTGTCACATGTGCCAAGAACCATGAT
GAACCTTGCGATGTGACAAGGAAACCCAACAGCCGAGCTCTGTGTGGCCTCCAGCAATGCCCTTCTAGCCGGAGAGTTCTGAAACCAAAC
AAAGGCACTATTTCCAATGGAAAAAACCCACCAACACTAAAGCCCGTCCCTCCACCTACATCCAGGCCCAGAATGCTGACCACACCCACA
GGGCCTGAGTCTATGAGCACAAGCACTCCAGCAATCAGCAGCCCTAGTCCTACCACAGCCTCCAAAGAAGGAGACCTGGGTGGGAAACAG
TGGCAAGATAGCTCAACCCAACCTGAGCTGAGCTCTCGCTATCTCATTTCCACTGGAAGCACTTCCCAGCCCATCCTCACTTCCCAATCC
TTGAGCATTCAGCCAAGTGAGGAAAATGTTTCCAGTTCAGATACTGGTCCTACCTCGGAGGGAGGCCTTGTAGCTACAACAACAAGTGGT
TCTGGCTTGTCATCTTCCCGCAACCCTATCACTTGGCCTGTGACTCCATTTTACAATACCTTGACCAAAGGTCCAGAAATGGAGATTCAC
AGTGGCTCAGGGGAAGAAAGAGAACAGCCTGAGGACAAAGATGAAAGCAATCCTGTAATATGGACCAAGATCAGAGTACCTGGAAATGAC
GCTCCAGTGGAAAGTACAGAAATGCCACTTGCACCTCCACTAACACCAGATCTCAGCAGGGAGTCCTGGTGGCCACCCTTCAGCACAGTA
ATGGAAGGACTGCTCCCCAGCCAAAGGCCCACTACTTCCGAAACTGGGACACCCAGAGTTGAGGGGATGGTTACTGAAAAGCCAGCCAAC
ACTCTGCTCCCTCTGGGAGGAGACCACCAGCCAGAACCCTCAGGAAAGACGGCAAACCGTAACCACCTGAAACTTCCAAACAACATGAAC
CAAACAAAAAGTTCTGAACCAGTCCTGACTGAGGAGGATGCAACAAGTCTGATTACTGAGGGCTTTTTGCTAAATGCCTCCAATTACAAG
CAGCTCACAAACGGCCACGGCTCTGCACACTGGATCGTCGGAAACTGGAGCGAGTGCTCCACCACATGTGGCCTGGGGGCCTACTGGAGA
AGGGTGGAGTGCAGCACCCAGATGGATTCTGACTGTGCGGCCATCCAGAGACCTGACCCTGCAAAAAGATGCCACCTCCGTCCCTGTGCT
GGCTGGAAAGTGGGAAACTGGAGCAAGTGCTCCAGAAACTGCAGTGGGGGCTTCAAGATACGCGAGATTCAGTGCGTGGACAGCCGGGAC
CACCGGAACCTGAGGCCATTTCACTGCCAGTTCCTGGCCGGCATTCCTCCCCCATTGAGCATGAGCTGTAACCCGGAGCCCTGTGAGGCG
TGGCAGGTGGAGCCTTGGAGCCAGTGCTCCAGGTCCTGTGGAGGTGGAGTTCAGGAGAGAGGAGTGTTCTGTCCAGGAGGCCTCTGTGAT
TGGACAAAAAGACCCACATCCACCATGTCTTGCAATGAGCACCTGTGCTGTCACTGGGCCACTGGGAACTGGGACCTGTGTTCCACTTCC
TGTGGAGGTGGCTTTCAGAAGAGGACTGTCCAATGTGTGCCCTCAGAGGGCAATAAAACTGAAGACCAAGACCAATGTCTATGTGATCAC
AAACCCAGACCTCCAGAATTCAAAAAATGCAACCAGCAGGCCTGCAAGAAAAGTGCCGATTTACTTTGCACTAAGGACAAACTGTCAGCC
AGTTTCTGCCAGACACTGAAAGCCATGAAGAAATGTTCTGTGCCCACCGTGAGGGCTGAGTGCTGCTTCTCGTGTCCCCAGACACACATC
ACACACACCCAAAGGCAAAGAAGGCAACGGTTGCTCCAAAAGTCAAAAGAACTCTAAGCCCAAAAGGAAGCCAGCTTCCACCAGACTGCA
GCAGCCTGCTGACCATGACATGCTTTAGCCCTGGGAGCTGCTTCGTTGAGGTTTTGCTTCATATATTTCAGATTCAGCTTTGGGTCATGA
TGAAACAAAATCCATTGTGTTCCTCTAGCCACCGAATGTCCCTCACAGGAGGCCTAGGCTGCCGTACTTGCTGCTCCCTGATAGGAAGGT
GAAATAGCTAGGAGAATCAGGCAGCACCTGGTATCGGCTCCTGGGAAAGGTGCCAGGTTAGACAGATTTGTGAAATACTGTATTTTTGTT
CTCCCTTAAAGATAAAAACAAAGAGACCAGCTATTTCCCTGACTACCTCAAGAGTATCAGGCAACACTTACCCAGGGGACAAATAATCTT
CTTAATTTATCTTGATGAATACCTTTCTTTTTTTTTTCTTGCCTCCCTGCCTGGGGCAGCTGCTATTTAAAATGTCACAGCGGAGCTTTA
GGAACATTCCTTTAATTCATCCAGGCAGAGGACTGCTTTCTTCACCCCATGTTCAACTAGGGCAGGAAGTGCTGGTTACATCCCTCAGTC
TCTTCCTCCATCCCTGTAGGGCTCCATATCTGGGCTGCTTAGAGTCTCCTGCCAACCTTGGGACACTAGACTAAGAGGAAACAGGCATAA
GAAACACAGCCTAAGGGGTTTAGGTCACTTACACAGAAAACACTTCTGGTTTGAAGAGCATTTCTATGAAAACTCGTAAAATGCAAATGA
GCAGAAATCAATTTCTTAATATTACAGAAAAGGAACTGTGGGCCTTTATTCTTCCCACTTTCCTGGCAAATACACACTCCTTTGCAGAAG
GGAAAATGTGTCTTCCTGGCTGACTTCCTCCCATCCTCCAGTCCCCACAGGAGGCCTGAGCTCAGGTCCCACCATCGTCTTGCTGCAGGG
GCTGTATATGCAAAGACCACTATGACCAGCTCTAGGGCTGCCACCTGTCCTCACCTCTTCTCAGGTTGGAAAATGGAGGTTCCATATTAA
AATATTTCAAAGAACCAGGTAAATTGTACTAAGTACAAGAACATAGTGCAAACTTCTAATCTAGAGAAAAAACATTTCTAAAAAGTAAGG
TAAAGGGGATCTACTCCTCAGTGTACCCAATATGTAGTTAGTCTTAAAGATCTTTTACTTTGGGGAGAACAGGTGAATCAGGGAGTCCAA
AGAAACTGAAATGAAAGTTAGAATGCTTGTTCTGGATGTTCCTACCTCCCACCAGAAGTCAAAGTAGGCTTGGTCTCAAATTCAGAGCAA
ATTTCTAGACAAAGTGATTTCTAAGGGAAGGTACTTACATGAACTGAACCCAGAGAAAGAGGGTAAGTGGGTGGGTGGAGGGGCATAAGC
TTCAAATGAAAGAAGATATCAGAACCAATTCTTGACAGGGAGAAAGGCAAGGATGTGGCCTTCATGTGATGGGCAGCATATTTTCTGACT
CATGCACAGATACACTTAATACTCCTCATGGAACACAATATCCCACGTCTCCCTTTACCTATCCGTTCAGCAGAATGGTGCTATTAAAAA
AATGGTGCTAATATCTAGATGGTGGCAGAATTAATGTAAACATAGATAGGCATACAAATGGGTAAGTGTATGTGAAACTCTCCATATACA
TCTTCTGTTAAACATGTAACGGTGTTGCTGACCAATGCCAGTTTTATTGCTTGGGTACCTTGAATTTAAGATTTAATATTATGTGCTTTT
TATTTTTTTCCAAGCCATTAACGTGTATTACTCTCATGAATTCCTGTGAAAAATAAAACAGTGGGATTGGGATGAAATTCAAGATAGACC
AGAAACAGGAGGAAAGTACAAATGTTTACCTAAAGCCAGAGAATTTATTTCTAGATGATAATTACATTATTGTATTCTCTGCCTTTAAAC
ATAAACATTGCTGGCCGATAGCAATCTCTGGTGAATAATGGTTTTCGAGGAGAGGAGACACTTAAATTGTTAGTGACATGAGTGGAGGAG
AATCTGATATTTACTAATGAGGCAGTTTGCAAAGACTGTCCCTGAAGTGTAGTGTAGTCTTTCAGGGGGATTCATTTAGTAAGCTAGATT
GATTTAACCTGGTACTGTACTAGCATAGGGTCAAATACGTGTCATCAGAGACCTGGGTATGACCAGGCTTACAAAACTCAGGAACAAACT
CAGATTCCTACTGACCTCAACCAACTAAACTAGGCCAAATTTCTCCGTGTACAAAATGGACCACGTTATTTACAATCCACGTGGTGGAGA
AGATGGTAGACATGTGGAGAGAGTTTGGCCAGGTGCTCCATTCTAGGTCTTTTTCCAGTTTCTCAAAGGCAGAACATTGGCTCCTAATTA
TTTGCCATGGATATTTGCTTCCTGTTCTGGAGCTATGTTGTAAGACAGCTGTGTGATGTCCATCATTCTTGACTCCAGAATGAAGACAGG
GCTTGCTGTTTTCTGTCCTGTTGGTATCATCTGTTGCCTTGGCGATCACTCAGTGATGAGTCGTCAGTATTTTGACATGTCCCAGTGCTT
GCTGTACAAGAGGGGACTCAGATCAACAGGAAGACTCTGAAGACAGGAACCTGCATGGTATCTTACATCTTTGATACTTGGGTGCTGATA
TGAAGCAGAGTTGTTGATTTACTTTATCTAGGCCCTTCTTTCTTCTCACCTGGATCAAGCAACTGAGAAGTGTATCAGGAGACACTGGAT
ACATATCTCTATGAAATAGAGAGGGCCATCGCAGGGCCTGGTACTTAACTACATTAACGTTCTAAAACCCAGTTTGGTTTACGTTGTCTT
TCACAGTAGTATATTTAGCTCTTCTCTGGAAAGTTGTGGGTTAATATAATTCTTAAACATGAAAATGTAATTAAACACACCACGAGAGAA
CAATATTCCAGGAGACTTAATAGTGATTACTTTCTTCAATCAGGAAATCGTTTCAGTGCCTCCTTTGTAGGAATGCTTTGTTTTGTGATG
GGTTTTCTTAAAGAAGAGCACACCTCCGTCCAATCTCCTGAGACAGCCACGTCTCCGCTGACATCCCACTGTGATGCTTTCAGATAGTCA
GTGAATGTTTCTGATAACCTTCATCCAGTATCTGAAACACAATGTGAGAGATTATATTGTTTTAGATAATAACATCCCATTTAGTTGACT
AAAATCTTCCAAACTCTGAAAGCTGCACACTGCTACTCCAGAGAGTGCAGGTCTTAGCTCTTCTCCTTTCTGACTTCAAGATGAATCTTT
GGGACGATGTTTCTGGTGCTTGGTCCACAGTGATTCACTTTTGAAGGAGAGGCCACATGACATGAACTGCCTGGTGTTACAACCTAGCTA
ACATATTTGATGCTACTCCTGTTGTCTGTACTGCTTATTCAAGTAGTATTCTAAGTTATGTTACTAAAAAACATGGTGGGTAAAGCACAA
TCCTACCCATCATTGTCCTCCAAAATAATTGTATGACATACACGGCCCAGCCCATTGCCCTCCCTGCATCTCTGTGCTGCTTTGCCATTT
CCCCTTCTACCCAGCCTCCTCAAGGGGTACCTTGGTGGATATTTCAGTACTTAAAACCAGACTGTAATCATAACCTCCCTCTGTGTGGCA

>14742_14742_2_CD9-ADAMTS12_CD9_chr12_6334700_ENST00000009180_ADAMTS12_chr5_33684160_ENST00000504830_length(amino acids)=1441AA_BP=58
MPVKGGTKCIKYLLFGFNFIFWLAGIAVLAIGLWLRFDSQTKSIFEQETNNNNSSFYTDSVNISQKQELWREKWERHNLPSRSLSRRSIS
KERWVETLVVADTKMIEYHGSENVESYILTIMNMVTGLFHNPSIGNAIHIVVVRLILLEEEEQGLKIVHHAEKTLSSFCKWQKSINPKSD
LNPVHHDVAVLLTRKDICAGFNRPCETLGLSHLSGMCQPHRSCNINEDSGLPLAFTIAHELGHSFGIQHDGKENDCEPVGRHPYIMSRQL
QYDPTPLTWSKCSEEYITRFLDRGWGFCLDDIPKKKGLKSKVIAPGVIYDVHHQCQLQYGPNATFCQEVENVCQTLWCSVKGFCRSKLDA
AADGTQCGEKKWCMAGKCITVGKKPESIPGGWGRWSPWSHCSRTCGAGVQSAERLCNNPEPKFGGKYCTGERKRYRLCNVHPCRSEAPTF
RQMQCSEFDTVPYKNELYHWFPIFNPAHPCELYCRPIDGQFSEKMLDAVIDGTPCFEGGNSRNVCINGICKMVGCDYEIDSNATEDRCGV
CLGDGSSCQTVRKMFKQKEGSGYVDIGLIPKGARDIRVMEIEGAGNFLAIRSEDPEKYYLNGGFIIQWNGNYKLAGTVFQYDRKGDLEKL
MATGPTNESVWIQLLFQVTNPGIKYEYTIQKDGLDNDVEQQMYFWQYGHWTECSVTCGTGIRRQTAHCIKKGRGMVKATFCDPETQPNGR
QKKCHEKACPPRWWAGEWEACSATCGPHGEKKRTVLCIQTMVSDEQALPPTDCQHLLKPKTLLSCNRDILCPSDWTVGNWSECSVSCGGG
VRIRSVTCAKNHDEPCDVTRKPNSRALCGLQQCPSSRRVLKPNKGTISNGKNPPTLKPVPPPTSRPRMLTTPTGPESMSTSTPAISSPSP
TTASKEGDLGGKQWQDSSTQPELSSRYLISTGSTSQPILTSQSLSIQPSEENVSSSDTGPTSEGGLVATTTSGSGLSSSRNPITWPVTPF
YNTLTKGPEMEIHSGSGEEREQPEDKDESNPVIWTKIRVPGNDAPVESTEMPLAPPLTPDLSRESWWPPFSTVMEGLLPSQRPTTSETGT
PRVEGMVTEKPANTLLPLGGDHQPEPSGKTANRNHLKLPNNMNQTKSSEPVLTEEDATSLITEGFLLNASNYKQLTNGHGSAHWIVGNWS
ECSTTCGLGAYWRRVECSTQMDSDCAAIQRPDPAKRCHLRPCAGWKVGNWSKCSRNCSGGFKIREIQCVDSRDHRNLRPFHCQFLAGIPP
PLSMSCNPEPCEAWQVEPWSQCSRSCGGGVQERGVFCPGGLCDWTKRPTSTMSCNEHLCCHWATGNWDLCSTSCGGGFQKRTVQCVPSEG
NKTEDQDQCLCDHKPRPPEFKKCNQQACKKSADLLCTKDKLSASFCQTLKAMKKCSVPTVRAECCFSCPQTHITHTQRQRRQRLLQKSKE

--------------------------------------------------------------
>14742_14742_3_CD9-ADAMTS12_CD9_chr12_6334700_ENST00000382518_ADAMTS12_chr5_33684160_ENST00000352040_length(transcript)=4514nt_BP=611nt
CTGCCCAGCCCTCAGCTGTGTTATTATTCGGTGATAGGTATTTGCTAATTACTTCCAAAAGCCTCCCATCTGTCATCCCACCCAGACTGC
GCGCTTCTAATTCCTCCTACCCCACATGCTGTGCCCAATGAAAAGTATGGTCAGCGAGCGAAGGTTTGCAAGGAGACAGACGAGGGCGAA
ATTAAGCCAGGCGGCTTCCCTTTAAATCCTCGCAAAGCAGAAGGGCCCCTCACTCTGGCAGCAGGCCTTGGCCAAGGGGCCTTTAGCCCT
GACGACCCGGGGAAGAGTCTCCCAAAGCAGAACGCCCGGTCCGGCGCCCAGACCAAACGCGGGGGAACCGGAAGGGCGAGGCCTCCACCG
CCAGGTCCCGCCAGTCCCAGCTGCGCGCGCCCCCCAGTCCCGCACCCGTTCGGCCCAGGCTAAGTTAGCCCTCACCATGCCGGTCAAAGG
AGGCACCAAGTGCATCAAATACCTGCTGTTCGGATTTAACTTCATCTTCTGGCTTGCCGGGATTGCTGTCCTTGCCATTGGACTATGGCT
CCGATTCGACTCTCAGACCAAGAGCATCTTCGAGCAAGAAACTAATAATAATAATTCCAGCTTCTACACAGACAGTGTTAACATCTCCCA
GAAGCAAGAGCTATGGCGGGAGAAGTGGGAGAGGCACAACTTGCCAAGCAGAAGCCTCTCTCGGCGTTCCATCAGCAAGGAGAGATGGGT
GGAGACACTGGTGGTGGCCGACACAAAGATGATTGAATACCATGGGAGTGAGAATGTGGAGTCCTACATCCTCACCATCATGAACATGGT
CACTGGGTTGTTCCATAACCCAAGCATTGGCAATGCAATTCACATTGTTGTGGTTCGGCTCATTCTACTCGAAGAAGAAGAGCAAGGACT
GAAAATAGTTCACCATGCAGAAAAGACACTGTCTAGCTTCTGCAAGTGGCAGAAGAGTATCAATCCCAAGAGTGACCTCAATCCTGTTCA
TCACGACGTGGCTGTCCTTCTCACCAGAAAGGACATCTGTGCTGGTTTCAATCGCCCCTGCGAGACCCTGGGCCTGTCTCACCTTTCAGG
AATGTGTCAGCCTCACCGCAGTTGTAACATCAATGAAGATTCGGGACTCCCTCTGGCTTTCACAATTGCCCATGAGCTAGGACACAGCTT
CGGCATCCAGCATGATGGGAAAGAAAATGACTGTGAGCCTGTGGGCAGACATCCGTACATCATGTCCCGCCAGCTCCAGTACGATCCCAC
TCCGCTGACATGGTCCAAGTGCAGCGAGGAGTACATCACCCGCTTCTTGGACCGAGGCTGGGGGTTCTGTCTTGATGACATACCTAAAAA
GAAAGGCTTGAAGTCCAAGGTCATTGCCCCCGGAGTGATCTATGATGTTCACCACCAGTGCCAGCTACAATATGGACCCAATGCTACCTT
CTGCCAGGAAGTAGAAAACGTCTGCCAGACACTGTGGTGCTCCGTGAAGGGCTTTTGTCGCTCTAAGCTGGACGCTGCTGCAGATGGAAC
TCAATGTGGTGAGAAGAAGTGGTGTATGGCAGGCAAGTGCATCACAGTGGGGAAGAAACCAGAGAGCATTCCTGGAGGCTGGGGCCGCTG
GTCACCCTGGTCCCACTGTTCCAGGACCTGTGGGGCTGGAGTCCAGAGCGCAGAGAGGCTCTGCAACAACCCCGAGCCAAAGTTTGGAGG
GAAATATTGCACTGGAGAAAGAAAACGCTATCGCTTGTGCAACGTCCACCCCTGTCGCTCAGAGGCACCAACATTTCGGCAGATGCAGTG
CAGTGAATTTGACACTGTTCCCTACAAGAATGAACTCTACCACTGGTTTCCCATTTTTAACCCAGGTTATGTTGACATTGGGCTCATTCC
AAAAGGAGCAAGGGACATAAGAGTGATGGAAATTGAGGGAGCTGGAAACTTCCTGGCCATCAGGAGTGAAGATCCTGAAAAATATTACCT
GAATGGAGGGTTTATTATCCAGTGGAACGGGAACTATAAGCTGGCAGGGACTGTCTTTCAGTATGACAGGAAAGGAGACCTGGAAAAGCT
GATGGCCACAGGTCCCACCAATGAGTCTGTGTGGATCCAGCTTCTATTCCAGGTGACTAACCCTGGCATCAAGTATGAGTACACAATCCA
GAAAGATGGCCTTGACAATGATGTTGAGCAGCAGATGTACTTCTGGCAGTACGGCCACTGGACAGAGTGCAGTGTGACCTGCGGGACAGG
TATCCGCCGCCAAACTGCCCATTGCATAAAGAAGGGCCGCGGGATGGTGAAAGCTACATTCTGTGACCCAGAAACACAGCCCAATGGGAG
ACAGAAGAAGTGCCATGAAAAGGCTTGTCCACCCAGGTGGTGGGCAGGGGAGTGGGAAGCATGCTCGGCGACATGCGGGCCCCACGGGGA
GAAGAAGCGAACCGTGCTGTGCATCCAGACCATGGTCTCTGACGAGCAGGCTCTCCCGCCCACAGACTGCCAGCACCTGCTGAAGCCCAA
GACCCTCCTTTCCTGCAACAGAGACATCCTGTGCCCCTCGGACTGGACAGTGGGCAACTGGAGTGAGTGTTCTGTTTCCTGTGGTGGTGG
AGTGCGGATTCGCAGTGTCACATGTGCCAAGAACCATGATGAACCTTGCGATGTGACAAGGAAACCCAACAGCCGAGCTCTGTGTGGCCT
CCAGCAATGCCCTTCTAGCCGGAGAGTTCTGAAACCAAACAAAGGCACTATTTCCAATGGAAAAAACCCACCAACACTAAAGCCCGTCCC
TCCACCTACATCCAGGCCCAGAATGCTGACCACACCCACAGGGCCTGAGTCTATGAGCACAAGCACTCCAGCAATCAGCAGCCCTAGTCC
TACCACAGCCTCCAAAGAAGGAGACCTGGGTGGGAAACAGTGGCAAGATAGCTCAACCCAACCTGAGCTGAGCTCTCGCTATCTCATTTC
CACTGGAAGCACTTCCCAGCCCATCCTCACTTCCCAATCCTTGAGCATTCAGCCAAGTGAGGAAAATGTTTCCAGTTCAGATACTGGTCC
TACCTCGGAGGGAGGCCTTGTAGCTACAACAACAAGTGGTTCTGGCTTGTCATCTTCCCGCAACCCTATCACTTGGCCTGTGACTCCATT
TTACAATACCTTGACCAAAGGTCCAGAAATGGAGATTCACAGTGGCTCAGGGGAAGAAAGAGAACAGCCTGAGGACAAAGATGAAAGCAA
TCCTGTAATATGGACCAAGATCAGAGTACCTGGAAATGACGCTCCAGTGGAAAGTACAGAAATGCCACTTGCACCTCCACTAACACCAGA
TCTCAGCAGGGAGTCCTGGTGGCCACCCTTCAGCACAGTAATGGAAGGACTGCTCCCCAGCCAAAGGCCCACTACTTCCGAAACTGGGAC
ACCCAGAGTTGAGGGGATGGTTACTGAAAAGCCAGCCAACACTCTGCTCCCTCTGGGAGGAGACCACCAGCCAGAACCCTCAGGAAAGAC
GGCAAACCGTAACCACCTGAAACTTCCAAACAACATGAACCAAACAAAAAGTTCTGAACCAGTCCTGACTGAGGAGGATGCAACAAGTCT
GATTACTGAGGGCTTTTTGCTAAATGCCTCCAATTACAAGCAGCTCACAAACGGCCACGGCTCTGCACACTGGATCGTCGGAAACTGGAG
CGAGTGCTCCACCACATGTGGCCTGGGGGCCTACTGGAGAAGGGTGGAGTGCAGCACCCAGATGGATTCTGACTGTGCGGCCATCCAGAG
ACCTGACCCTGCAAAAAGATGCCACCTCCGTCCCTGTGCTGGCTGGAAAGTGGGAAACTGGAGCAAGTGCTCCAGAAACTGCAGTGGGGG
CTTCAAGATACGCGAGATTCAGTGCGTGGACAGCCGGGACCACCGGAACCTGAGGCCATTTCACTGCCAGTTCCTGGCCGGCATTCCTCC
CCCATTGAGCATGAGCTGTAACCCGGAGCCCTGTGAGGCGTGGCAGGTGGAGCCTTGGAGCCAGTGCTCCAGGTCCTGTGGAGGTGGAGT
TCAGGAGAGAGGAGTGTTCTGTCCAGGAGGCCTCTGTGATTGGACAAAAAGACCCACATCCACCATGTCTTGCAATGAGCACCTGTGCTG
TCACTGGGCCACTGGGAACTGGGACCTGTGTTCCACTTCCTGTGGAGGTGGCTTTCAGAAGAGGACTGTCCAATGTGTGCCCTCAGAGGG
CAATAAAACTGAAGACCAAGACCAATGTCTATGTGATCACAAACCCAGACCTCCAGAATTCAAAAAATGCAACCAGCAGGCCTGCAAGAA
AAGTGCCGATTTACTTTGCACTAAGGACAAACTGTCAGCCAGTTTCTGCCAGACACTGAAAGCCATGAAGAAATGTTCTGTGCCCACCGT
GAGGGCTGAGTGCTGCTTCTCGTGTCCCCAGACACACATCACACACACCCAAAGGCAAAGAAGGCAACGGTTGCTCCAAAAGTCAAAAGA

>14742_14742_3_CD9-ADAMTS12_CD9_chr12_6334700_ENST00000382518_ADAMTS12_chr5_33684160_ENST00000352040_length(amino acids)=1419AA_BP=121
MAKGPLALTTRGRVSQSRTPGPAPRPNAGEPEGRGLHRQVPPVPAARAPQSRTRSAQAKLALTMPVKGGTKCIKYLLFGFNFIFWLAGIA
VLAIGLWLRFDSQTKSIFEQETNNNNSSFYTDSVNISQKQELWREKWERHNLPSRSLSRRSISKERWVETLVVADTKMIEYHGSENVESY
ILTIMNMVTGLFHNPSIGNAIHIVVVRLILLEEEEQGLKIVHHAEKTLSSFCKWQKSINPKSDLNPVHHDVAVLLTRKDICAGFNRPCET
LGLSHLSGMCQPHRSCNINEDSGLPLAFTIAHELGHSFGIQHDGKENDCEPVGRHPYIMSRQLQYDPTPLTWSKCSEEYITRFLDRGWGF
CLDDIPKKKGLKSKVIAPGVIYDVHHQCQLQYGPNATFCQEVENVCQTLWCSVKGFCRSKLDAAADGTQCGEKKWCMAGKCITVGKKPES
IPGGWGRWSPWSHCSRTCGAGVQSAERLCNNPEPKFGGKYCTGERKRYRLCNVHPCRSEAPTFRQMQCSEFDTVPYKNELYHWFPIFNPG
YVDIGLIPKGARDIRVMEIEGAGNFLAIRSEDPEKYYLNGGFIIQWNGNYKLAGTVFQYDRKGDLEKLMATGPTNESVWIQLLFQVTNPG
IKYEYTIQKDGLDNDVEQQMYFWQYGHWTECSVTCGTGIRRQTAHCIKKGRGMVKATFCDPETQPNGRQKKCHEKACPPRWWAGEWEACS
ATCGPHGEKKRTVLCIQTMVSDEQALPPTDCQHLLKPKTLLSCNRDILCPSDWTVGNWSECSVSCGGGVRIRSVTCAKNHDEPCDVTRKP
NSRALCGLQQCPSSRRVLKPNKGTISNGKNPPTLKPVPPPTSRPRMLTTPTGPESMSTSTPAISSPSPTTASKEGDLGGKQWQDSSTQPE
LSSRYLISTGSTSQPILTSQSLSIQPSEENVSSSDTGPTSEGGLVATTTSGSGLSSSRNPITWPVTPFYNTLTKGPEMEIHSGSGEEREQ
PEDKDESNPVIWTKIRVPGNDAPVESTEMPLAPPLTPDLSRESWWPPFSTVMEGLLPSQRPTTSETGTPRVEGMVTEKPANTLLPLGGDH
QPEPSGKTANRNHLKLPNNMNQTKSSEPVLTEEDATSLITEGFLLNASNYKQLTNGHGSAHWIVGNWSECSTTCGLGAYWRRVECSTQMD
SDCAAIQRPDPAKRCHLRPCAGWKVGNWSKCSRNCSGGFKIREIQCVDSRDHRNLRPFHCQFLAGIPPPLSMSCNPEPCEAWQVEPWSQC
SRSCGGGVQERGVFCPGGLCDWTKRPTSTMSCNEHLCCHWATGNWDLCSTSCGGGFQKRTVQCVPSEGNKTEDQDQCLCDHKPRPPEFKK

--------------------------------------------------------------
>14742_14742_4_CD9-ADAMTS12_CD9_chr12_6334700_ENST00000382518_ADAMTS12_chr5_33684160_ENST00000504830_length(transcript)=8415nt_BP=611nt
CTGCCCAGCCCTCAGCTGTGTTATTATTCGGTGATAGGTATTTGCTAATTACTTCCAAAAGCCTCCCATCTGTCATCCCACCCAGACTGC
GCGCTTCTAATTCCTCCTACCCCACATGCTGTGCCCAATGAAAAGTATGGTCAGCGAGCGAAGGTTTGCAAGGAGACAGACGAGGGCGAA
ATTAAGCCAGGCGGCTTCCCTTTAAATCCTCGCAAAGCAGAAGGGCCCCTCACTCTGGCAGCAGGCCTTGGCCAAGGGGCCTTTAGCCCT
GACGACCCGGGGAAGAGTCTCCCAAAGCAGAACGCCCGGTCCGGCGCCCAGACCAAACGCGGGGGAACCGGAAGGGCGAGGCCTCCACCG
CCAGGTCCCGCCAGTCCCAGCTGCGCGCGCCCCCCAGTCCCGCACCCGTTCGGCCCAGGCTAAGTTAGCCCTCACCATGCCGGTCAAAGG
AGGCACCAAGTGCATCAAATACCTGCTGTTCGGATTTAACTTCATCTTCTGGCTTGCCGGGATTGCTGTCCTTGCCATTGGACTATGGCT
CCGATTCGACTCTCAGACCAAGAGCATCTTCGAGCAAGAAACTAATAATAATAATTCCAGCTTCTACACAGACAGTGTTAACATCTCCCA
GAAGCAAGAGCTATGGCGGGAGAAGTGGGAGAGGCACAACTTGCCAAGCAGAAGCCTCTCTCGGCGTTCCATCAGCAAGGAGAGATGGGT
GGAGACACTGGTGGTGGCCGACACAAAGATGATTGAATACCATGGGAGTGAGAATGTGGAGTCCTACATCCTCACCATCATGAACATGGT
CACTGGGTTGTTCCATAACCCAAGCATTGGCAATGCAATTCACATTGTTGTGGTTCGGCTCATTCTACTCGAAGAAGAAGAGCAAGGACT
GAAAATAGTTCACCATGCAGAAAAGACACTGTCTAGCTTCTGCAAGTGGCAGAAGAGTATCAATCCCAAGAGTGACCTCAATCCTGTTCA
TCACGACGTGGCTGTCCTTCTCACCAGAAAGGACATCTGTGCTGGTTTCAATCGCCCCTGCGAGACCCTGGGCCTGTCTCACCTTTCAGG
AATGTGTCAGCCTCACCGCAGTTGTAACATCAATGAAGATTCGGGACTCCCTCTGGCTTTCACAATTGCCCATGAGCTAGGACACAGCTT
CGGCATCCAGCATGATGGGAAAGAAAATGACTGTGAGCCTGTGGGCAGACATCCGTACATCATGTCCCGCCAGCTCCAGTACGATCCCAC
TCCGCTGACATGGTCCAAGTGCAGCGAGGAGTACATCACCCGCTTCTTGGACCGAGGCTGGGGGTTCTGTCTTGATGACATACCTAAAAA
GAAAGGCTTGAAGTCCAAGGTCATTGCCCCCGGAGTGATCTATGATGTTCACCACCAGTGCCAGCTACAATATGGACCCAATGCTACCTT
CTGCCAGGAAGTAGAAAACGTCTGCCAGACACTGTGGTGCTCCGTGAAGGGCTTTTGTCGCTCTAAGCTGGACGCTGCTGCAGATGGAAC
TCAATGTGGTGAGAAGAAGTGGTGTATGGCAGGCAAGTGCATCACAGTGGGGAAGAAACCAGAGAGCATTCCTGGAGGCTGGGGCCGCTG
GTCACCCTGGTCCCACTGTTCCAGGACCTGTGGGGCTGGAGTCCAGAGCGCAGAGAGGCTCTGCAACAACCCCGAGCCAAAGTTTGGAGG
GAAATATTGCACTGGAGAAAGAAAACGCTATCGCTTGTGCAACGTCCACCCCTGTCGCTCAGAGGCACCAACATTTCGGCAGATGCAGTG
CAGTGAATTTGACACTGTTCCCTACAAGAATGAACTCTACCACTGGTTTCCCATTTTTAACCCAGCACATCCTTGTGAGCTCTACTGCCG
ACCCATAGATGGCCAGTTTTCTGAGAAAATGCTGGATGCTGTCATTGATGGTACCCCTTGCTTTGAAGGCGGCAACAGCAGAAATGTCTG
TATTAATGGCATATGTAAGATGGTTGGCTGTGACTATGAGATCGATTCCAATGCCACCGAGGATCGCTGCGGTGTGTGCCTGGGAGATGG
CTCTTCCTGCCAGACTGTGAGAAAGATGTTTAAGCAGAAGGAAGGATCTGGTTATGTTGACATTGGGCTCATTCCAAAAGGAGCAAGGGA
CATAAGAGTGATGGAAATTGAGGGAGCTGGAAACTTCCTGGCCATCAGGAGTGAAGATCCTGAAAAATATTACCTGAATGGAGGGTTTAT
TATCCAGTGGAACGGGAACTATAAGCTGGCAGGGACTGTCTTTCAGTATGACAGGAAAGGAGACCTGGAAAAGCTGATGGCCACAGGTCC
CACCAATGAGTCTGTGTGGATCCAGCTTCTATTCCAGGTGACTAACCCTGGCATCAAGTATGAGTACACAATCCAGAAAGATGGCCTTGA
CAATGATGTTGAGCAGCAGATGTACTTCTGGCAGTACGGCCACTGGACAGAGTGCAGTGTGACCTGCGGGACAGGTATCCGCCGCCAAAC
TGCCCATTGCATAAAGAAGGGCCGCGGGATGGTGAAAGCTACATTCTGTGACCCAGAAACACAGCCCAATGGGAGACAGAAGAAGTGCCA
TGAAAAGGCTTGTCCACCCAGGTGGTGGGCAGGGGAGTGGGAAGCATGCTCGGCGACATGCGGGCCCCACGGGGAGAAGAAGCGAACCGT
GCTGTGCATCCAGACCATGGTCTCTGACGAGCAGGCTCTCCCGCCCACAGACTGCCAGCACCTGCTGAAGCCCAAGACCCTCCTTTCCTG
CAACAGAGACATCCTGTGCCCCTCGGACTGGACAGTGGGCAACTGGAGTGAGTGTTCTGTTTCCTGTGGTGGTGGAGTGCGGATTCGCAG
TGTCACATGTGCCAAGAACCATGATGAACCTTGCGATGTGACAAGGAAACCCAACAGCCGAGCTCTGTGTGGCCTCCAGCAATGCCCTTC
TAGCCGGAGAGTTCTGAAACCAAACAAAGGCACTATTTCCAATGGAAAAAACCCACCAACACTAAAGCCCGTCCCTCCACCTACATCCAG
GCCCAGAATGCTGACCACACCCACAGGGCCTGAGTCTATGAGCACAAGCACTCCAGCAATCAGCAGCCCTAGTCCTACCACAGCCTCCAA
AGAAGGAGACCTGGGTGGGAAACAGTGGCAAGATAGCTCAACCCAACCTGAGCTGAGCTCTCGCTATCTCATTTCCACTGGAAGCACTTC
CCAGCCCATCCTCACTTCCCAATCCTTGAGCATTCAGCCAAGTGAGGAAAATGTTTCCAGTTCAGATACTGGTCCTACCTCGGAGGGAGG
CCTTGTAGCTACAACAACAAGTGGTTCTGGCTTGTCATCTTCCCGCAACCCTATCACTTGGCCTGTGACTCCATTTTACAATACCTTGAC
CAAAGGTCCAGAAATGGAGATTCACAGTGGCTCAGGGGAAGAAAGAGAACAGCCTGAGGACAAAGATGAAAGCAATCCTGTAATATGGAC
CAAGATCAGAGTACCTGGAAATGACGCTCCAGTGGAAAGTACAGAAATGCCACTTGCACCTCCACTAACACCAGATCTCAGCAGGGAGTC
CTGGTGGCCACCCTTCAGCACAGTAATGGAAGGACTGCTCCCCAGCCAAAGGCCCACTACTTCCGAAACTGGGACACCCAGAGTTGAGGG
GATGGTTACTGAAAAGCCAGCCAACACTCTGCTCCCTCTGGGAGGAGACCACCAGCCAGAACCCTCAGGAAAGACGGCAAACCGTAACCA
CCTGAAACTTCCAAACAACATGAACCAAACAAAAAGTTCTGAACCAGTCCTGACTGAGGAGGATGCAACAAGTCTGATTACTGAGGGCTT
TTTGCTAAATGCCTCCAATTACAAGCAGCTCACAAACGGCCACGGCTCTGCACACTGGATCGTCGGAAACTGGAGCGAGTGCTCCACCAC
ATGTGGCCTGGGGGCCTACTGGAGAAGGGTGGAGTGCAGCACCCAGATGGATTCTGACTGTGCGGCCATCCAGAGACCTGACCCTGCAAA
AAGATGCCACCTCCGTCCCTGTGCTGGCTGGAAAGTGGGAAACTGGAGCAAGTGCTCCAGAAACTGCAGTGGGGGCTTCAAGATACGCGA
GATTCAGTGCGTGGACAGCCGGGACCACCGGAACCTGAGGCCATTTCACTGCCAGTTCCTGGCCGGCATTCCTCCCCCATTGAGCATGAG
CTGTAACCCGGAGCCCTGTGAGGCGTGGCAGGTGGAGCCTTGGAGCCAGTGCTCCAGGTCCTGTGGAGGTGGAGTTCAGGAGAGAGGAGT
GTTCTGTCCAGGAGGCCTCTGTGATTGGACAAAAAGACCCACATCCACCATGTCTTGCAATGAGCACCTGTGCTGTCACTGGGCCACTGG
GAACTGGGACCTGTGTTCCACTTCCTGTGGAGGTGGCTTTCAGAAGAGGACTGTCCAATGTGTGCCCTCAGAGGGCAATAAAACTGAAGA
CCAAGACCAATGTCTATGTGATCACAAACCCAGACCTCCAGAATTCAAAAAATGCAACCAGCAGGCCTGCAAGAAAAGTGCCGATTTACT
TTGCACTAAGGACAAACTGTCAGCCAGTTTCTGCCAGACACTGAAAGCCATGAAGAAATGTTCTGTGCCCACCGTGAGGGCTGAGTGCTG
CTTCTCGTGTCCCCAGACACACATCACACACACCCAAAGGCAAAGAAGGCAACGGTTGCTCCAAAAGTCAAAAGAACTCTAAGCCCAAAA
GGAAGCCAGCTTCCACCAGACTGCAGCAGCCTGCTGACCATGACATGCTTTAGCCCTGGGAGCTGCTTCGTTGAGGTTTTGCTTCATATA
TTTCAGATTCAGCTTTGGGTCATGATGAAACAAAATCCATTGTGTTCCTCTAGCCACCGAATGTCCCTCACAGGAGGCCTAGGCTGCCGT
ACTTGCTGCTCCCTGATAGGAAGGTGAAATAGCTAGGAGAATCAGGCAGCACCTGGTATCGGCTCCTGGGAAAGGTGCCAGGTTAGACAG
ATTTGTGAAATACTGTATTTTTGTTCTCCCTTAAAGATAAAAACAAAGAGACCAGCTATTTCCCTGACTACCTCAAGAGTATCAGGCAAC
ACTTACCCAGGGGACAAATAATCTTCTTAATTTATCTTGATGAATACCTTTCTTTTTTTTTTCTTGCCTCCCTGCCTGGGGCAGCTGCTA
TTTAAAATGTCACAGCGGAGCTTTAGGAACATTCCTTTAATTCATCCAGGCAGAGGACTGCTTTCTTCACCCCATGTTCAACTAGGGCAG
GAAGTGCTGGTTACATCCCTCAGTCTCTTCCTCCATCCCTGTAGGGCTCCATATCTGGGCTGCTTAGAGTCTCCTGCCAACCTTGGGACA
CTAGACTAAGAGGAAACAGGCATAAGAAACACAGCCTAAGGGGTTTAGGTCACTTACACAGAAAACACTTCTGGTTTGAAGAGCATTTCT
ATGAAAACTCGTAAAATGCAAATGAGCAGAAATCAATTTCTTAATATTACAGAAAAGGAACTGTGGGCCTTTATTCTTCCCACTTTCCTG
GCAAATACACACTCCTTTGCAGAAGGGAAAATGTGTCTTCCTGGCTGACTTCCTCCCATCCTCCAGTCCCCACAGGAGGCCTGAGCTCAG
GTCCCACCATCGTCTTGCTGCAGGGGCTGTATATGCAAAGACCACTATGACCAGCTCTAGGGCTGCCACCTGTCCTCACCTCTTCTCAGG
TTGGAAAATGGAGGTTCCATATTAAAATATTTCAAAGAACCAGGTAAATTGTACTAAGTACAAGAACATAGTGCAAACTTCTAATCTAGA
GAAAAAACATTTCTAAAAAGTAAGGTAAAGGGGATCTACTCCTCAGTGTACCCAATATGTAGTTAGTCTTAAAGATCTTTTACTTTGGGG
AGAACAGGTGAATCAGGGAGTCCAAAGAAACTGAAATGAAAGTTAGAATGCTTGTTCTGGATGTTCCTACCTCCCACCAGAAGTCAAAGT
AGGCTTGGTCTCAAATTCAGAGCAAATTTCTAGACAAAGTGATTTCTAAGGGAAGGTACTTACATGAACTGAACCCAGAGAAAGAGGGTA
AGTGGGTGGGTGGAGGGGCATAAGCTTCAAATGAAAGAAGATATCAGAACCAATTCTTGACAGGGAGAAAGGCAAGGATGTGGCCTTCAT
GTGATGGGCAGCATATTTTCTGACTCATGCACAGATACACTTAATACTCCTCATGGAACACAATATCCCACGTCTCCCTTTACCTATCCG
TTCAGCAGAATGGTGCTATTAAAAAAATGGTGCTAATATCTAGATGGTGGCAGAATTAATGTAAACATAGATAGGCATACAAATGGGTAA
GTGTATGTGAAACTCTCCATATACATCTTCTGTTAAACATGTAACGGTGTTGCTGACCAATGCCAGTTTTATTGCTTGGGTACCTTGAAT
TTAAGATTTAATATTATGTGCTTTTTATTTTTTTCCAAGCCATTAACGTGTATTACTCTCATGAATTCCTGTGAAAAATAAAACAGTGGG
ATTGGGATGAAATTCAAGATAGACCAGAAACAGGAGGAAAGTACAAATGTTTACCTAAAGCCAGAGAATTTATTTCTAGATGATAATTAC
ATTATTGTATTCTCTGCCTTTAAACATAAACATTGCTGGCCGATAGCAATCTCTGGTGAATAATGGTTTTCGAGGAGAGGAGACACTTAA
ATTGTTAGTGACATGAGTGGAGGAGAATCTGATATTTACTAATGAGGCAGTTTGCAAAGACTGTCCCTGAAGTGTAGTGTAGTCTTTCAG
GGGGATTCATTTAGTAAGCTAGATTGATTTAACCTGGTACTGTACTAGCATAGGGTCAAATACGTGTCATCAGAGACCTGGGTATGACCA
GGCTTACAAAACTCAGGAACAAACTCAGATTCCTACTGACCTCAACCAACTAAACTAGGCCAAATTTCTCCGTGTACAAAATGGACCACG
TTATTTACAATCCACGTGGTGGAGAAGATGGTAGACATGTGGAGAGAGTTTGGCCAGGTGCTCCATTCTAGGTCTTTTTCCAGTTTCTCA
AAGGCAGAACATTGGCTCCTAATTATTTGCCATGGATATTTGCTTCCTGTTCTGGAGCTATGTTGTAAGACAGCTGTGTGATGTCCATCA
TTCTTGACTCCAGAATGAAGACAGGGCTTGCTGTTTTCTGTCCTGTTGGTATCATCTGTTGCCTTGGCGATCACTCAGTGATGAGTCGTC
AGTATTTTGACATGTCCCAGTGCTTGCTGTACAAGAGGGGACTCAGATCAACAGGAAGACTCTGAAGACAGGAACCTGCATGGTATCTTA
CATCTTTGATACTTGGGTGCTGATATGAAGCAGAGTTGTTGATTTACTTTATCTAGGCCCTTCTTTCTTCTCACCTGGATCAAGCAACTG
AGAAGTGTATCAGGAGACACTGGATACATATCTCTATGAAATAGAGAGGGCCATCGCAGGGCCTGGTACTTAACTACATTAACGTTCTAA
AACCCAGTTTGGTTTACGTTGTCTTTCACAGTAGTATATTTAGCTCTTCTCTGGAAAGTTGTGGGTTAATATAATTCTTAAACATGAAAA
TGTAATTAAACACACCACGAGAGAACAATATTCCAGGAGACTTAATAGTGATTACTTTCTTCAATCAGGAAATCGTTTCAGTGCCTCCTT
TGTAGGAATGCTTTGTTTTGTGATGGGTTTTCTTAAAGAAGAGCACACCTCCGTCCAATCTCCTGAGACAGCCACGTCTCCGCTGACATC
CCACTGTGATGCTTTCAGATAGTCAGTGAATGTTTCTGATAACCTTCATCCAGTATCTGAAACACAATGTGAGAGATTATATTGTTTTAG
ATAATAACATCCCATTTAGTTGACTAAAATCTTCCAAACTCTGAAAGCTGCACACTGCTACTCCAGAGAGTGCAGGTCTTAGCTCTTCTC
CTTTCTGACTTCAAGATGAATCTTTGGGACGATGTTTCTGGTGCTTGGTCCACAGTGATTCACTTTTGAAGGAGAGGCCACATGACATGA
ACTGCCTGGTGTTACAACCTAGCTAACATATTTGATGCTACTCCTGTTGTCTGTACTGCTTATTCAAGTAGTATTCTAAGTTATGTTACT
AAAAAACATGGTGGGTAAAGCACAATCCTACCCATCATTGTCCTCCAAAATAATTGTATGACATACACGGCCCAGCCCATTGCCCTCCCT
GCATCTCTGTGCTGCTTTGCCATTTCCCCTTCTACCCAGCCTCCTCAAGGGGTACCTTGGTGGATATTTCAGTACTTAAAACCAGACTGT

>14742_14742_4_CD9-ADAMTS12_CD9_chr12_6334700_ENST00000382518_ADAMTS12_chr5_33684160_ENST00000504830_length(amino acids)=1504AA_BP=121
MAKGPLALTTRGRVSQSRTPGPAPRPNAGEPEGRGLHRQVPPVPAARAPQSRTRSAQAKLALTMPVKGGTKCIKYLLFGFNFIFWLAGIA
VLAIGLWLRFDSQTKSIFEQETNNNNSSFYTDSVNISQKQELWREKWERHNLPSRSLSRRSISKERWVETLVVADTKMIEYHGSENVESY
ILTIMNMVTGLFHNPSIGNAIHIVVVRLILLEEEEQGLKIVHHAEKTLSSFCKWQKSINPKSDLNPVHHDVAVLLTRKDICAGFNRPCET
LGLSHLSGMCQPHRSCNINEDSGLPLAFTIAHELGHSFGIQHDGKENDCEPVGRHPYIMSRQLQYDPTPLTWSKCSEEYITRFLDRGWGF
CLDDIPKKKGLKSKVIAPGVIYDVHHQCQLQYGPNATFCQEVENVCQTLWCSVKGFCRSKLDAAADGTQCGEKKWCMAGKCITVGKKPES
IPGGWGRWSPWSHCSRTCGAGVQSAERLCNNPEPKFGGKYCTGERKRYRLCNVHPCRSEAPTFRQMQCSEFDTVPYKNELYHWFPIFNPA
HPCELYCRPIDGQFSEKMLDAVIDGTPCFEGGNSRNVCINGICKMVGCDYEIDSNATEDRCGVCLGDGSSCQTVRKMFKQKEGSGYVDIG
LIPKGARDIRVMEIEGAGNFLAIRSEDPEKYYLNGGFIIQWNGNYKLAGTVFQYDRKGDLEKLMATGPTNESVWIQLLFQVTNPGIKYEY
TIQKDGLDNDVEQQMYFWQYGHWTECSVTCGTGIRRQTAHCIKKGRGMVKATFCDPETQPNGRQKKCHEKACPPRWWAGEWEACSATCGP
HGEKKRTVLCIQTMVSDEQALPPTDCQHLLKPKTLLSCNRDILCPSDWTVGNWSECSVSCGGGVRIRSVTCAKNHDEPCDVTRKPNSRAL
CGLQQCPSSRRVLKPNKGTISNGKNPPTLKPVPPPTSRPRMLTTPTGPESMSTSTPAISSPSPTTASKEGDLGGKQWQDSSTQPELSSRY
LISTGSTSQPILTSQSLSIQPSEENVSSSDTGPTSEGGLVATTTSGSGLSSSRNPITWPVTPFYNTLTKGPEMEIHSGSGEEREQPEDKD
ESNPVIWTKIRVPGNDAPVESTEMPLAPPLTPDLSRESWWPPFSTVMEGLLPSQRPTTSETGTPRVEGMVTEKPANTLLPLGGDHQPEPS
GKTANRNHLKLPNNMNQTKSSEPVLTEEDATSLITEGFLLNASNYKQLTNGHGSAHWIVGNWSECSTTCGLGAYWRRVECSTQMDSDCAA
IQRPDPAKRCHLRPCAGWKVGNWSKCSRNCSGGFKIREIQCVDSRDHRNLRPFHCQFLAGIPPPLSMSCNPEPCEAWQVEPWSQCSRSCG
GGVQERGVFCPGGLCDWTKRPTSTMSCNEHLCCHWATGNWDLCSTSCGGGFQKRTVQCVPSEGNKTEDQDQCLCDHKPRPPEFKKCNQQA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CD9-ADAMTS12


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CD9-ADAMTS12


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CD9-ADAMTS12


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneCD9C0007131Non-Small Cell Lung Carcinoma1CTD_human
HgeneCD9C0009402Colorectal Carcinoma1CTD_human
HgeneCD9C0009404Colorectal Neoplasms1CTD_human
HgeneCD9C0017636Glioblastoma1CTD_human
HgeneCD9C0023467Leukemia, Myelocytic, Acute1CTD_human
HgeneCD9C0023890Liver Cirrhosis1CTD_human
HgeneCD9C0026998Acute Myeloid Leukemia, M11CTD_human
HgeneCD9C0027654Embryonal Neoplasm1CTD_human
HgeneCD9C0027658Neoplasms, Germ Cell and Embryonal1CTD_human
HgeneCD9C0027746Nerve Degeneration1CTD_human
HgeneCD9C0033578Prostatic Neoplasms1CTD_human
HgeneCD9C0205851Germ cell tumor1CTD_human
HgeneCD9C0205852Neoplasms, Embryonal and Mixed1CTD_human
HgeneCD9C0239946Fibrosis, Liver1CTD_human
HgeneCD9C0334588Giant Cell Glioblastoma1CTD_human
HgeneCD9C0376358Malignant neoplasm of prostate1CTD_human
HgeneCD9C0740345Germ Cell Cancer1CTD_human
HgeneCD9C0751364Cancer, Embryonal1CTD_human
HgeneCD9C0751365Cancer, Embryonal and Mixed1CTD_human
HgeneCD9C1621958Glioblastoma Multiforme1CTD_human
HgeneCD9C1879321Acute Myeloid Leukemia (AML-M2)1CTD_human
TgeneC0036341Schizophrenia1PSYGENET