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Fusion Gene Summary | |
Fusion Gene ORF analysis | |
Fusion Genomic Features | |
Fusion Protein Features | |
Fusion Gene Sequence | |
Fusion Gene PPI analysis | |
Related Drugs | |
Related Diseases |
Fusion gene:B4GALT5-ERBB4 (FusionGDB2 ID:HG9334TG2066) |
Fusion Gene Summary for B4GALT5-ERBB4 |
Fusion gene summary |
Fusion gene information | Fusion gene name: B4GALT5-ERBB4 | Fusion gene ID: hg9334tg2066 | Hgene | Tgene | Gene symbol | B4GALT5 | ERBB4 | Gene ID | 9334 | 2066 |
Gene name | beta-1,4-galactosyltransferase 5 | erb-b2 receptor tyrosine kinase 4 | |
Synonyms | B4Gal-T5|BETA4-GALT-IV|beta4Gal-T5|beta4GalT-V|gt-V | ALS19|HER4|p180erbB4 | |
Cytomap | ('B4GALT5')('ERBB4') 20q13.13 | 2q34 | |
Type of gene | protein-coding | protein-coding | |
Description | beta-1,4-galactosyltransferase 5UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 5UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 5beta-1,4-GalT IIbeta-1,4-GalT I | receptor tyrosine-protein kinase erbB-4avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4human epidermal growth factor receptor 4proto-oncogene-like protein c-ErbB-4tyrosine kinase-type cell surface receptor HER4v-erb-a erythroblastic | |
Modification date | 20200313 | 20200327 | |
UniProtAcc | O43286 | Q15303 | |
Ensembl transtripts involved in fusion gene | ENST00000371711, | ||
Fusion gene scores | * DoF score | 21 X 14 X 12=3528 | 18 X 16 X 8=2304 |
# samples | 25 | 17 | |
** MAII score | log2(25/3528*10)=-3.81885056089543 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(17/2304*10)=-3.76053406530461 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
Context | PubMed: B4GALT5 [Title/Abstract] AND ERBB4 [Title/Abstract] AND fusion [Title/Abstract] | ||
Most frequent breakpoint | |||
Anticipated loss of major functional domain due to fusion event. |
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
Partner | Gene | GO ID | GO term | PubMed ID |
Tgene | ERBB4 | GO:0007165 | signal transduction | 10572067 |
Tgene | ERBB4 | GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway | 10353604|18334220 |
Tgene | ERBB4 | GO:0016477 | cell migration | 9135143 |
Tgene | ERBB4 | GO:0018108 | peptidyl-tyrosine phosphorylation | 18334220 |
Tgene | ERBB4 | GO:0046777 | protein autophosphorylation | 18334220 |
Fusion gene information * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
ChimerKB3 | . | . | B4GALT5 | chr20 | 48330113 | - | ERBB4 | chr2 | 212812341 | - |
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Fusion Gene ORF analysis for B4GALT5-ERBB4 |
Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
5CDS-5UTR | ENST00000371711 | ENST00000484474 | B4GALT5 | chr20 | 48330113 | - | ERBB4 | chr2 | 212812341 | - |
In-frame | ENST00000371711 | ENST00000342788 | B4GALT5 | chr20 | 48330113 | - | ERBB4 | chr2 | 212812341 | - |
In-frame | ENST00000371711 | ENST00000402597 | B4GALT5 | chr20 | 48330113 | - | ERBB4 | chr2 | 212812341 | - |
In-frame | ENST00000371711 | ENST00000436443 | B4GALT5 | chr20 | 48330113 | - | ERBB4 | chr2 | 212812341 | - |
ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
ENST00000371711 | B4GALT5 | chr20 | 48330113 | - | ENST00000436443 | ERBB4 | chr2 | 212812341 | - | 11842 | 303 | 357 | 3947 | 1196 |
ENST00000371711 | B4GALT5 | chr20 | 48330113 | - | ENST00000342788 | ERBB4 | chr2 | 212812341 | - | 11890 | 303 | 357 | 3995 | 1212 |
ENST00000371711 | B4GALT5 | chr20 | 48330113 | - | ENST00000402597 | ERBB4 | chr2 | 212812341 | - | 3966 | 303 | 357 | 3965 | 1202 |
DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
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Fusion Genomic Features for B4GALT5-ERBB4 |
FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
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Fusion Protein Features for B4GALT5-ERBB4 |
Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr20:/chr2:) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
Main function of each fusion partner protein. (from UniProt) |
Hgene | Tgene |
B4GALT5 | ERBB4 |
FUNCTION: Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer) (PubMed:24498430). LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation (By similarity). Plays a role in the glycosylation of BMPR1A and regulation of its protein stability (By similarity). Essential for extraembryonic development during early embryogenesis (By similarity). {ECO:0000250|UniProtKB:Q9JMK0, ECO:0000269|PubMed:24498430}. | FUNCTION: Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins and EGF family members and regulates development of the heart, the central nervous system and the mammary gland, gene transcription, cell proliferation, differentiation, migration and apoptosis. Required for normal cardiac muscle differentiation during embryonic development, and for postnatal cardiomyocyte proliferation. Required for normal development of the embryonic central nervous system, especially for normal neural crest cell migration and normal axon guidance. Required for mammary gland differentiation, induction of milk proteins and lactation. Acts as cell-surface receptor for the neuregulins NRG1, NRG2, NRG3 and NRG4 and the EGF family members BTC, EREG and HBEGF. Ligand binding triggers receptor dimerization and autophosphorylation at specific tyrosine residues that then serve as binding sites for scaffold proteins and effectors. Ligand specificity and signaling is modulated by alternative splicing, proteolytic processing, and by the formation of heterodimers with other ERBB family members, thereby creating multiple combinations of intracellular phosphotyrosines that trigger ligand- and context-specific cellular responses. Mediates phosphorylation of SHC1 and activation of the MAP kinases MAPK1/ERK2 and MAPK3/ERK1. Isoform JM-A CYT-1 and isoform JM-B CYT-1 phosphorylate PIK3R1, leading to the activation of phosphatidylinositol 3-kinase and AKT1 and protect cells against apoptosis. Isoform JM-A CYT-1 and isoform JM-B CYT-1 mediate reorganization of the actin cytoskeleton and promote cell migration in response to NRG1. Isoform JM-A CYT-2 and isoform JM-B CYT-2 lack the phosphotyrosine that mediates interaction with PIK3R1, and hence do not phosphorylate PIK3R1, do not protect cells against apoptosis, and do not promote reorganization of the actin cytoskeleton and cell migration. Proteolytic processing of isoform JM-A CYT-1 and isoform JM-A CYT-2 gives rise to the corresponding soluble intracellular domains (4ICD) that translocate to the nucleus, promote nuclear import of STAT5A, activation of STAT5A, mammary epithelium differentiation, cell proliferation and activation of gene expression. The ERBB4 soluble intracellular domains (4ICD) colocalize with STAT5A at the CSN2 promoter to regulate transcription of milk proteins during lactation. The ERBB4 soluble intracellular domains can also translocate to mitochondria and promote apoptosis. {ECO:0000269|PubMed:10348342, ECO:0000269|PubMed:10353604, ECO:0000269|PubMed:10358079, ECO:0000269|PubMed:10722704, ECO:0000269|PubMed:10867024, ECO:0000269|PubMed:11178955, ECO:0000269|PubMed:11390655, ECO:0000269|PubMed:12807903, ECO:0000269|PubMed:15534001, ECO:0000269|PubMed:15746097, ECO:0000269|PubMed:16251361, ECO:0000269|PubMed:16778220, ECO:0000269|PubMed:16837552, ECO:0000269|PubMed:17486069, ECO:0000269|PubMed:17638867, ECO:0000269|PubMed:19098003, ECO:0000269|PubMed:20858735, ECO:0000269|PubMed:8383326, ECO:0000269|PubMed:8617750, ECO:0000269|PubMed:9135143, ECO:0000269|PubMed:9168115, ECO:0000269|PubMed:9334263}. |
Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
- In-frame and retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
- In-frame and not-retained protein feature among the 13 regional features. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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Fusion Gene Sequence for B4GALT5-ERBB4 |
For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
>8762_8762_1_B4GALT5-ERBB4_B4GALT5_chr20_48330113_ENST00000371711_ERBB4_chr2_212812341_ENST00000342788_length(transcript)=11890nt_BP=303nt ATGTGGCCCGGCCCGCGACGGCCGGCGGCTGGGAGCGGCGAGGCGGCGGCGGCGGCGAGTGGCGGCCCGCGAGGCCCGGGAGGCGGTGGC CGAGGCCCAGGCGGTGGCGGCGGCGGCCCAGGAGGCGGCGGACGGGGAGCTGCGGGAGCAGGCCCGGCCTGGCTCTCTAGCGGCCGCCTG GCTGCAGCATGCGCGCCCGCCGGGGGCTGCTGCGGCTGCCGCGCCGCTCGCTGCTCGCCGCGCTCTTCTTCTTTTCTCTCTCGTCCTCGC TGCTGTACTTCGTCTATGTGGCGCCCGGCATAGTCTGTTCGAGAAGTCACAGGCTACGTGTTAGTGGCTCTTAATCAGTTTCGTTACCTG CCTCTGGAGAATTTACGCATTATTCGTGGGACAAAACTTTATGAGGATCGATATGCCTTGGCAATATTTTTAAACTACAGAAAAGATGGA AACTTTGGACTTCAAGAACTTGGATTAAAGAACTTGACAGAAATCCTAAATGGTGGAGTCTATGTAGACCAGAACAAATTCCTTTGTTAT GCAGACACCATTCATTGGCAAGATATTGTTCGGAACCCATGGCCTTCCAACTTGACTCTTGTGTCAACAAATGGTAGTTCAGGATGTGGA CGTTGCCATAAGTCCTGTACTGGCCGTTGCTGGGGACCCACAGAAAATCATTGCCAGACTTTGACAAGGACGGTGTGTGCAGAACAATGT GACGGCAGATGCTACGGACCTTACGTCAGTGACTGCTGCCATCGAGAATGTGCTGGAGGCTGCTCAGGACCTAAGGACACAGACTGCTTT GCCTGCATGAATTTCAATGACAGTGGAGCATGTGTTACTCAGTGTCCCCAAACCTTTGTCTACAATCCAACCACCTTTCAACTGGAGCAC AATTTCAATGCAAAGTACACATATGGAGCATTCTGTGTCAAGAAATGTCCACATAACTTTGTGGTAGATTCCAGTTCTTGTGTGCGTGCC TGCCCTAGTTCCAAGATGGAAGTAGAAGAAAATGGGATTAAAATGTGTAAACCTTGCACTGACATTTGCCCAAAAGCTTGTGATGGCATT GGCACAGGATCATTGATGTCAGCTCAGACTGTGGATTCCAGTAACATTGACAAATTCATAAACTGTACCAAGATCAATGGGAATTTGATC TTTCTAGTCACTGGTATTCATGGGGACCCTTACAATGCAATTGAAGCCATAGACCCAGAGAAACTGAACGTCTTTCGGACAGTCAGAGAG ATAACAGGTTTCCTGAACATACAGTCATGGCCACCAAACATGACTGACTTCAGTGTTTTTTCTAACCTGGTGACCATTGGTGGAAGAGTA CTCTATAGTGGCCTGTCCTTGCTTATCCTCAAGCAACAGGGCATCACCTCTCTACAGTTCCAGTCCCTGAAGGAAATCAGCGCAGGAAAC ATCTATATTACTGACAACAGCAACCTGTGTTATTATCATACCATTAACTGGACAACACTCTTCAGCACAATCAACCAGAGAATAGTAATC CGGGACAACAGAAAAGCTGAAAATTGTACTGCTGAAGGAATGGTGTGCAACCATCTGTGTTCCAGTGATGGCTGTTGGGGACCTGGGCCA GACCAATGTCTGTCGTGTCGCCGCTTCAGTAGAGGAAGGATCTGCATAGAGTCTTGTAACCTCTATGATGGTGAATTTCGGGAGTTTGAG AATGGCTCCATCTGTGTGGAGTGTGACCCCCAGTGTGAGAAGATGGAAGATGGCCTCCTCACATGCCATGGACCGGGTCCTGACAACTGT ACAAAGTGCTCTCATTTTAAAGATGGCCCAAACTGTGTGGAAAAATGTCCAGATGGCTTACAGGGGGCAAACAGTTTCATTTTCAAGTAT GCTGATCCAGATCGGGAGTGCCACCCATGCCATCCAAACTGCACCCAAGGGTGTAACGGTCCCACTAGTCATGACTGCATTTACTACCCA TGGACGGGCCATTCCACTTTACCACAACATGCTAGAACTCCCCTGATTGCAGCTGGAGTAATTGGTGGGCTCTTCATTCTGGTCATTGTG GGTCTGACATTTGCTGTTTATGTTAGAAGGAAGAGCATCAAAAAGAAAAGAGCCTTGAGAAGATTCTTGGAAACAGAGTTGGTGGAACCA TTAACTCCCAGTGGCACAGCACCCAATCAAGCTCAACTTCGTATTTTGAAAGAAACTGAGCTGAAGAGGGTAAAAGTCCTTGGCTCAGGT GCTTTTGGAACGGTTTATAAAGGTATTTGGGTACCTGAAGGAGAAACTGTGAAGATTCCTGTGGCTATTAAGATTCTTAATGAGACAACT GGTCCCAAGGCAAATGTGGAGTTCATGGATGAAGCTCTGATCATGGCAAGTATGGATCATCCACACCTAGTCCGGTTGCTGGGTGTGTGT CTGAGCCCAACCATCCAGCTGGTTACTCAACTTATGCCCCATGGCTGCCTGTTGGAGTATGTCCACGAGCACAAGGATAACATTGGATCA CAACTGCTGCTTAACTGGTGTGTCCAGATAGCTAAGGGAATGATGTACCTGGAAGAAAGACGACTCGTTCATCGGGATTTGGCAGCCCGT AATGTCTTAGTGAAATCTCCAAACCATGTGAAAATCACAGATTTTGGGCTAGCCAGACTCTTGGAAGGAGATGAAAAAGAGTACAATGCT GATGGAGGAAAGATGCCAATTAAATGGATGGCTCTGGAGTGTATACATTACAGGAAATTCACCCATCAGAGTGACGTTTGGAGCTATGGA GTTACTATATGGGAACTGATGACCTTTGGAGGAAAACCCTATGATGGAATTCCAACGCGAGAAATCCCTGATTTATTAGAGAAAGGAGAA CGTTTGCCTCAGCCTCCCATCTGCACTATTGACGTTTACATGGTCATGGTCAAATGTTGGATGATTGATGCTGACAGTAGACCTAAATTT AAGGAACTGGCTGCTGAGTTTTCAAGGATGGCTCGAGACCCTCAAAGATACCTAGTTATTCAGGGTGATGATCGTATGAAGCTTCCCAGT CCAAATGACAGCAAGTTCTTTCAGAATCTCTTGGATGAAGAGGATTTGGAAGATATGATGGATGCTGAGGAGTACTTGGTCCCTCAGGCT TTCAACATCCCACCTCCCATCTATACTTCCAGAGCAAGAATTGACTCGAATAGGAGTGAAATTGGACACAGCCCTCCTCCTGCCTACACC CCCATGTCAGGAAACCAGTTTGTATACCGAGATGGAGGTTTTGCTGCTGAACAAGGAGTGTCTGTGCCCTACAGAGCCCCAACTAGCACA ATTCCAGAAGCTCCTGTGGCACAGGGTGCTACTGCTGAGATTTTTGATGACTCCTGCTGTAATGGCACCCTACGCAAGCCAGTGGCACCC CATGTCCAAGAGGACAGTAGCACCCAGAGGTACAGTGCTGACCCCACCGTGTTTGCCCCAGAACGGAGCCCACGAGGAGAGCTGGATGAG GAAGGTTACATGACTCCTATGCGAGACAAACCCAAACAAGAATACCTGAATCCAGTGGAGGAGAACCCTTTTGTTTCTCGGAGAAAAAAT GGAGACCTTCAAGCATTGGATAATCCCGAATATCACAATGCATCCAATGGTCCACCCAAGGCCGAGGATGAGTATGTGAATGAGCCACTG TACCTCAACACCTTTGCCAACACCTTGGGAAAAGCTGAGTACCTGAAGAACAACATACTGTCAATGCCAGAGAAGGCCAAGAAAGCGTTT GACAACCCTGACTACTGGAACCACAGCCTGCCACCTCGGAGCACCCTTCAGCACCCAGACTACCTGCAGGAGTACAGCACAAAATATTTT TATAAACAGAATGGGCGGATCCGGCCTATTGTGGCAGAGAATCCTGAATACCTCTCTGAGTTCTCCCTGAAGCCAGGCACTGTGCTGCCG CCTCCACCTTACAGACACCGGAATACTGTGGTGTAAGCTCAGTTGTGGTTTTTTAGGTGGAGAGACACACCTGCTCCAATTTCCCCACCC CCCTCTCTTTCTCTGGTGGTCTTCCTTCTACCCCAAGGCCAGTAGTTTTGACACTTCCCAGTGGAAGATACAGAGATGCAATGATAGTTA TGTGCTTACCTAACTTGAACATTAGAGGGAAAGACTGAAAGAGAAAGATAGGAGGAACCACAATGTTTCTTCATTTCTCTGCATGGGTTG GTCAGGAGAATGAAACAGCTAGAGAAGGACCAGAAAATGTAAGGCAATGCTGCCTACTATCAAACTAGCTGTCACTTTTTTTCTTTTTCT TTTTCTTTCTTTGTTTCTTTCTTCCTCTTCTTTTTTTTTTTTTTTTTTAAAGCAGATGGTTGAAACACCCATGCTATCTGTTCCTATCTG CAGGAACTGATGTGTGCATATTTAGCATCCCTGGAAATCATAATAAAGTTTCCATTAGAACAAAAGAATAACATTTTCTATAACATATGA TGGTGTCTGAAATTGAGAATCCAGTTTCTTTCCCCAGCAGTTTCTGTCCTAGCAAGTAAGAATGGCCAACTCAACTTTCATAATTTAAAA ATCTCCATTAAAGTTATAACTAGTAATTATGTTTTCAACACTTTTTGGTTTTTTTCATTTTGTTTTGCTCTGACCGATTCCTTTATATTT GCTCCCCTATTTTTGGCTTTAATTTCTAATTGCAAAGATGTTTACATCAAAGCTTCTTCACAGAATTTAAGCAAGAAATATTTTAATATA GTGAAATGGCCACTACTTTAAGTATACAATCTTTAAAATAAGAAAGGGAGGCTAATATTTTTCATGCTATCAAATTATCTTCACCCTCAT CCTTTACATTTTTCAACATTTTTTTTTCTCCATAAATGACACTACTTGATAGGCCGTTGGTTGTCTGAAGAGTAGAAGGGAAACTAAGAG ACAGTTCTCTGTGGTTCAGGAAAACTACTGATACTTTCAGGGGTGGCCCAATGAGGGAATCCATTGAACTGGAAGAAACACACTGGATTG GGTATGTCTACCTGGCAGATACTCAGAAATGTAGTTTGCACTTAAGCTGTAATTTTATTTGTTCTTTTTCTGAACTCCATTTTGGATTTT GAATCAAGCAATATGGAAGCAACCAGCAAATTAACTAATTTAAGTACATTTTTAAAAAAAGAGCTAAGATAAAGACTGTGGAAATGCCAA ACCAAGCAAATTAGGAACCTTGCAACGGTATCCAGGGACTATGATGAGAGGCCAGCACATTATCTTCATATGTCACCTTTGCTACGCAAG GAAATTTGTTCAGTTCGTATACTTCGTAAGAAGGAATGCGAGTAAGGATTGGCTTGAATTCCATGGAATTTCTAGTATGAGACTATTTAT ATGAAGTAGAAGGTAACTCTTTGCACATAAATTGGTATAATAAAAAGAAAAACACAAACATTCAAAGCTTAGGGATAGGTCCTTGGGTCA AAAGTTGTAAATAAATGTGAAACATCTTCTCATGCAATTATTTTATTATCCAACACACTAATCTTTTGATACTTTATATAATTCCCTTTC TTCATATACTGCATCCAGTACTAGAACCATCATTATTATGTATCATTTTGAAAGAATACCTGATGAGATGAAGGATGAGAACAAATGACA GAGATGAGTCTCCAAGTAAAGGGGGCCTCACATCAATAATTAGGAAACTTAGATATAAGTCGCCCTTTTCTGAAAATTCTACCCCAAGTC ATTTAGATTTTTAAAAAATATTTCTAATGTTAAAATATTGGGACCAAATTAGAATCAATAGTATAAGATTAATTAATTAGAGTAAAAATA TCTATTAAGGCAGAGAAAGTTTAGAGAAAAAAATCCAAAGAAATTTGTGTTTCTTCCTATTCTGAACAAGTAAATCCATCCATCCATCCA TCCAAACCTCCTTTATCTAACTGTGTCTACTAAAAGCACCATGTTTTGTGGGGAACACTCAGATAAATGGAATATCATCCTCAACTTCAA AATTCTATGATCTAGGAGATTTAATTAAAATGACATTTTAATTTTTCTATGCGTTCCAACAATCAGATTGCATAGTCTCTTTTGTGAATA GCTGTCATATAATCAGTTGTACTGTAAGATATCTCCTTTAAACTCATTTGGGATATAAGTTAAACATCCTTCAAATTGTTGATGTTGACA AACAGGATAATTTCAATAATATTATTCAAACATAAACTGGTCTAGGAGAATATTGCATCACTGACTAATTAGCCTATCTAGAGTCTAACT TCACCATTAAACCAAAAGCAGATGGTGGTCCTTGGCCAAGAATATTGGAGACATTGGAGTTGGTTTTTTTCTAAGCTATAAGAAGTGAGG CGAGCTGAAAAAGTATGGTAGAGCAGGAGAAGGGTTTGTGAGATTCCTTCTAGTGAAGTTCACCCTCAAACTTTTCAGGGGTAAAGACAC AGAGTGATTCAGGGGCCACAATCTAATAGCTCAGGGCTCTCCTATCCATTCAGAGAAGTCTCTAGGAAAAGGGATCTCATATCAGTACTT ATGAAAAATTGAATATAAGCCTCCCTTTCTAAATAAATCTGCATCGAGTCATCACAGCCCTCTTTTTGGATACTATACCTTGATTTTTTT TTTCTGATTTACAATATGCATATGGTTTCTACTGGGCTATAGAAAGCAGAATCACTCATTTTGGAGAAGGAAAAAATGAATAGTTAAAAC AAACTTTTAACTGTTAAGGTAACAGAAATGTATTTAGTGAATGTCTCTTTCCTCCTAAGAACACAAGACTTCTACATGTTGGGTAATACC TAGAGATGCATGTAGGAATAATCCAAAATGACCCAAATGCTTTATAATAGCACCACTTTATAATTCTTTTGAATGATTTCTGTAGTATAT AATTGACTTCAGTTGTTTGAGTGTTTTTTGTTTTATTTTTGTCCCCCCTGGGAAAACATATTTCAGCATGTATAAGAGGGAGAAAAAAAG TTTCATTCCTTCCAGAGAATAACTTATTTAGTCCAGTAGGGTAGAATTTTAAAATGTCAGTTAAAGTCTTCAAAGTGCTTGGGGGGATAT CAGATTCCAGAGGCCAATTGTAGCAATTGAAATTTGCAGAATCAATTATGTAAATCTGAGACAAATTAGTATTAAAATTACACGGAGTAT ATTTTTTAAATCACCCAACTTTGTAGATTATACCTATTTTGGGCAGGTATGGAAAAATTTTGCAGTTAAATGATTGCCTAAAGAAAGTGG TAAACAGGTGAGGAAAGATGGCCTCTGATCTAGGATAGATCCAGAACCACAAAGCATCTGCACCACAAAAGGTGTTAGACTACCAAGCAG CTCCTGGTTTTCTGCATAGTATTAGTAGCACAGCTTAGGATGAGAATCCTTTCTCCAGTAACATTCTTAAAATAGCATGAAAAACAACGC AAAACTCAAATTTCTATTAAAACACACAAACTAAAATCAAGTGATTCTTTTTTGTAGATTAGGGAGAAGGACTGAATATCTAATTTAAGA GAAGGAATAGTGTTTAAGTGTTATAGTGTGTGAGCTAATACCTTCTAAAGGAAAGACATGGCATGAAGATTGTGCATACTTACAATGCTA AGGAAAAATCAAGAAAAGGACTGTGTGAGGCTCTGCTACTAGATGAAGTTGGAAGGACTATTAATGTGCTTCTTGAAGTATCAAAAATGA AAAGAAAATTAAAATTGTTTAAGCCTGACAGGGAAGGATGTAAATACAAGTTTTTCTAGAGCTCTCTAACCTTTATTTCAAAACTGGAAT TATTCATCCATCTGTAATTGTTGATAATTTAACTAGTATATGTAGTTCATAAGGTAATAGAAAAGGTGATCATGAAAGCATGTATATAAC TGGACAGAACCACGATAATGCTATAAGATGTAGATTTAGTTAGGTTATCAGATGTTAAATGATTTTAATATTATTAAATAAATCAAACTA GAAAACTAACCACAAGTATAATGTAACAAAGTTAAATGCAGGATATAAAAATGTAGGATGGATTTTGCATAGTAAAAAGATAAGTTTGCC ATTTAAAATTGTTGTTTGTTGGGTTTAGCTGAAAGTAGGCATATATGGTTCCACTTGGGAAAACTTGCTTTAAAGCATTACAATGAACAA TTTTTTCTCATTCTCTTATTCCTTTATCACTTTTTAAATGTAAAGAAAATTGTATTTATTTATTTTTTTAAATAAACACCACCTTGCAGA ATTTAATAGGCAAACATGTTACATATGACTAAGTAAGGGTCTTCAAGATGAAGTAAAGAAAATGTAAATGTTCTATTACCTTATGCAGAG ACAAAAAAAAAAAGGAGTGGTGTCATTTAGCTAGCAAACAAACAAAATACAGTTAATTGGTGATATGTCCTTTCTTTTCTCACTATGCCC TCTTGCCTCCAAAAATGACAACAAAGAATCACAATTTTTCTGATAAATAAATGCTAAACCAAGCGTTTCAAACTATTGCATTGCCATTCT TTTGGACTTTAGTTATTAGAATGATGATTGTTATAGGGCAAATGAGAAATCCATGTGCATCAGCTTCTAGTTGTTAAAAAAACCAGATAA ATTAACTTCTACTGTATACTGTGGGCAGAGGATCCTAGAGCTGATCCTACAACATCAGCTTCTAGTTGTTAAAAAAAAAAAAAGAAACAG ATAAATTAACTTCTACTGTATATACTGTGGGCAGAGGATCTTACTGTGCCTCTGTTTGTGTACATGGACTTCGGTGTGTATCAGTTTGAA GGACAGCCTTGCCCCATGTAAACATATAAATGCAGATTGGTATCGCCTGGTTGCTATTTGCTTAAGAACAAATATTATACAGATGAGATC AGGCATAATTTTAAAAGATCATTATCAGTGGAGACCTCATTATTACTGATATTACAATGGGGCCAGTTTTTATACTTCTGGGTAGAATTA ATAAAATTTTTCTGATCCCAGAGATCTGAGTTCTCTCTGCAGTTGGAAACAAGAAGCTGTTGTGGGCATTGTGTCGGGCCAGGGGCCCTT GTGTTTGTGTGGGCAAATATCTTTTAGCAGTGTGAGCTGCTTTTTTCTTTTCATTAAAAGTCTCTCTAAAATAATAGAAATTTCAGATAC TCGGTTCAAGTCTCACTGATTTTGTAGAGGTCCAAAAATGTAGGATCTGTCACTTTTGCAGGCCCCTGCCTCACCTAATTCCTGGCCAGG TGACATTTTGGGCAGAAGTAAATGCTTCTATAGTCACAAGCTAAAATGACTCTAAGCCCCAATTTCACGGGGGGTATTCACATGCTTCCT CTGGAAAATACTCTTTGACAGTCAGCTTTGCAAGTAAGTGATTACCTTGTTAGGAATCAAAGAAAAATGTATTTCTCTCTGACCTTTAGA GGAAAATAGAATCCTTCCCTTTTTTGCCCATTGACACAACTGGCACTGCTCTCTTCCCTTTCTACCACCCTGGTTCAAAGTAGTCCCCCG ATGCTGTCCTGTTCCTTTCTTAAGCCATAGTGGATCTCTGAGATCCTACACCCCACTTTGTGAAACACTGACTTCATCTTTGCCCTCGAA TGCCTGATTTTTTCATAAGAGATTCTAGCAATTTGGACACTGTTTAAGTGAACTATCAAACTACCGCATAGAGAATATTTAAGCTATTAA AATTATGGTTTCCCATGAAGATCAATTCTCTGTGTCCTTCCCTATAGGAATTTGAGACGAGTTAGCCCTGTGATGAATCTTGAAACTCAC ATATGTCCACATACACTTGGTAGAACTTCGATTTAATCTTTACATAAAAGCTGTACATATAACCAAGAAGTTATTTTTGCCAGTAAATTA ACTTATTTGCTTTATTCATCTTATTTGGTTCCTAATCGTAAATATTTTGTAGCTGCTGTAAATTTTTTTCTCCCAAATGAGGAGTCTTAT TATCATAAAGGTAAAGGCTATTCAGCTTTGATAACCACCTGCAATTCTTTTTTGGATCATTCATCCATCTAACAAATACATAATGAGGAC AGTTCATGTTAATGAAAATCCATGTTGTTTAATAGAATGCCATCCTTTACCTACTTTTGCTCTTTATGGACGTTTTTCTTTTCATGCTCT AGTGAGCTTTCCCTATATCATGAGAAGTGGTTATATTTGTGCAAATATACAAATATAGGAAAACAAAGATTCATACCTGTAGGCAATAGT CTAACTTGTCCAAACCACTTTGCCTTTACTGCTATTTTTATCCCCAATGCGTAGATATTTCCCCCAGGCCTATAGCCTTTGTGAAGGAAA GCAAATCATACCTCCTGTATATTGACACGAATCTGGTTTTCAAATGTCATTTCCAGATTTTTTAGTTAATTGGGGGTTGTCCTTTTCCCT TAATGTGAGAGTCATTTTCCTGTATATTTCTGGATCTCTCAGGGGCTGGGAGGGGGGAGTGAGGGGACTACAACCATAGCACTCCAAGAA CCCTTTTGGGATTACTCCAGTAATCAACTACGAAAGTTATTTTCTAAATGTAGATATGTAAGGTGTTCTTTTAAAGTAAGGTACTTTGAA ATATGTAGCATAAACTGGTACTGCTGTTAAATGGGTCGATTATTAAACGGAGCAGCTGTGTGAGGGCAGCTAACTTTGAATGCCTGTCTC CCTGGCTGGTGTGTCTCCTTCTCATGTTGAGAGCACCAGGGATTGCGTGGCTGCATGCTGAAACCGCATTTTCCCATGGTGTATGACTAG TTCATCTCTTTCTTGAGCACCATTACAAGAAGATCAAATGAAAATGAGATCAATGTGGAAGACAATTCATAGCACAAAAAAAGTCATCTT AAATCTACTCTCAAACATTCATCTTATACATGCATCAAAGTAATTTACTGACATCAGTTTGGGTGAGAGAGGGAGTCACTTTACTGAAAA GGCAGAGGCTTAAGGTGTATACATTTGTACTCACTTCCTTATTTTCTTAACTTGTAAGCAGAAAACAAGCCCTCTCTCTTGTGAAGTATC TTCAAAGGATTGGGGTGCAAAAATACCTTGCTGGTAAGCCATCAATGTTTTATTTAAATCCCTGCATTCAAAGTTAGCTGCCTTTTTGAA ATAAACAAACAAAAAATACTACTGTATGTTTGAAAATGTGAATAGTATTTTTATAGCTTGTTAAAGACATGGCTAGTTGCATTTGTAAAT AAGTATAATGTTGCTTTGATTTTCTTTTGTGGACATCTTTATTTGGAACATAATTGTCTTTAGGGTTGATTTGTATATAAGTAATTGGCC TGTGATTGTTTCTTTTTTGGTTGGAAGTTATCATTTTGACATTACTTGTGATTCTGTGTTCAGCACTATTGTGATGTGTTCAACCTCTGC ACTCGCTTACACAATAGGATATGCCAATTGTGTGTGGTGTAATGTTATTTTGATTTTTTTCCATGTTATTGATGAAGGATCATGCACCTA ACACATACTAACTTTTTTAATGTTAGGCATATTTTTAGTATACTTTCTCTTATTCTTTCTTCTCCTCCAACCTTTTACCCATCCTCCTTC CTTTCCCTCATTCCTGTTGTTATTTGAGAATGAGGGAGAAACAGTATTTTACATTTATGTAATTAGGCTTTTCCGTTAGTTCTCAAGGAT CCTCTTTTGGCTCTTGGGAAAGAATTGTACCTGTACAAGGCAATTATAGAATGCGAACTGCTTTGCCTCATTCCATACTGATCATCCCAG CTGAACAATTTGAAAACTGTTCTGCCTTTTTGTTACATGAATCTGTCAGAAATATATTTTTAATTTAATATAAATGAAATTCAATAAAAT >8762_8762_1_B4GALT5-ERBB4_B4GALT5_chr20_48330113_ENST00000371711_ERBB4_chr2_212812341_ENST00000342788_length(amino acids)=1212AA_BP= MPLENLRIIRGTKLYEDRYALAIFLNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVSTNGSSGC GRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLE HNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGNL IFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAG NIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFREF ENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGANSFIFKYADPDRECHPCHPNCTQGCNGPTSHDCIYY PWTGHSTLPQHARTPLIAAGVIGGLFILVIVGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGS GAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIG SQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSY GVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLP SPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRARIDSNRSEIGHSPPPAYTPMSGNQFVYRDGGFAAEQGVSVPYRAPTS TIPEAPVAQGATAEIFDDSCCNGTLRKPVAPHVQEDSSTQRYSADPTVFAPERSPRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSRRK NGDLQALDNPEYHNASNGPPKAEDEYVNEPLYLNTFANTLGKAEYLKNNILSMPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKY -------------------------------------------------------------- >8762_8762_2_B4GALT5-ERBB4_B4GALT5_chr20_48330113_ENST00000371711_ERBB4_chr2_212812341_ENST00000402597_length(transcript)=3966nt_BP=303nt ATGTGGCCCGGCCCGCGACGGCCGGCGGCTGGGAGCGGCGAGGCGGCGGCGGCGGCGAGTGGCGGCCCGCGAGGCCCGGGAGGCGGTGGC CGAGGCCCAGGCGGTGGCGGCGGCGGCCCAGGAGGCGGCGGACGGGGAGCTGCGGGAGCAGGCCCGGCCTGGCTCTCTAGCGGCCGCCTG GCTGCAGCATGCGCGCCCGCCGGGGGCTGCTGCGGCTGCCGCGCCGCTCGCTGCTCGCCGCGCTCTTCTTCTTTTCTCTCTCGTCCTCGC TGCTGTACTTCGTCTATGTGGCGCCCGGCATAGTCTGTTCGAGAAGTCACAGGCTACGTGTTAGTGGCTCTTAATCAGTTTCGTTACCTG CCTCTGGAGAATTTACGCATTATTCGTGGGACAAAACTTTATGAGGATCGATATGCCTTGGCAATATTTTTAAACTACAGAAAAGATGGA AACTTTGGACTTCAAGAACTTGGATTAAAGAACTTGACAGAAATCCTAAATGGTGGAGTCTATGTAGACCAGAACAAATTCCTTTGTTAT GCAGACACCATTCATTGGCAAGATATTGTTCGGAACCCATGGCCTTCCAACTTGACTCTTGTGTCAACAAATGGTAGTTCAGGATGTGGA CGTTGCCATAAGTCCTGTACTGGCCGTTGCTGGGGACCCACAGAAAATCATTGCCAGACTTTGACAAGGACGGTGTGTGCAGAACAATGT GACGGCAGATGCTACGGACCTTACGTCAGTGACTGCTGCCATCGAGAATGTGCTGGAGGCTGCTCAGGACCTAAGGACACAGACTGCTTT GCCTGCATGAATTTCAATGACAGTGGAGCATGTGTTACTCAGTGTCCCCAAACCTTTGTCTACAATCCAACCACCTTTCAACTGGAGCAC AATTTCAATGCAAAGTACACATATGGAGCATTCTGTGTCAAGAAATGTCCACATAACTTTGTGGTAGATTCCAGTTCTTGTGTGCGTGCC TGCCCTAGTTCCAAGATGGAAGTAGAAGAAAATGGGATTAAAATGTGTAAACCTTGCACTGACATTTGCCCAAAAGCTTGTGATGGCATT GGCACAGGATCATTGATGTCAGCTCAGACTGTGGATTCCAGTAACATTGACAAATTCATAAACTGTACCAAGATCAATGGGAATTTGATC TTTCTAGTCACTGGTATTCATGGGGACCCTTACAATGCAATTGAAGCCATAGACCCAGAGAAACTGAACGTCTTTCGGACAGTCAGAGAG ATAACAGGTTTCCTGAACATACAGTCATGGCCACCAAACATGACTGACTTCAGTGTTTTTTCTAACCTGGTGACCATTGGTGGAAGAGTA CTCTATAGTGGCCTGTCCTTGCTTATCCTCAAGCAACAGGGCATCACCTCTCTACAGTTCCAGTCCCTGAAGGAAATCAGCGCAGGAAAC ATCTATATTACTGACAACAGCAACCTGTGTTATTATCATACCATTAACTGGACAACACTCTTCAGCACAATCAACCAGAGAATAGTAATC CGGGACAACAGAAAAGCTGAAAATTGTACTGCTGAAGGAATGGTGTGCAACCATCTGTGTTCCAGTGATGGCTGTTGGGGACCTGGGCCA GACCAATGTCTGTCGTGTCGCCGCTTCAGTAGAGGAAGGATCTGCATAGAGTCTTGTAACCTCTATGATGGTGAATTTCGGGAGTTTGAG AATGGCTCCATCTGTGTGGAGTGTGACCCCCAGTGTGAGAAGATGGAAGATGGCCTCCTCACATGCCATGGACCGGGTCCTGACAACTGT ACAAAGTGCTCTCATTTTAAAGATGGCCCAAACTGTGTGGAAAAATGTCCAGATGGCTTACAGGGGGCAAACAGTTTCATTTTCAAGTAT GCTGATCCAGATCGGGAGTGCCACCCATGCCATCCAAACTGCACCCAAGGGTGCATAGGCTCAAGTATTGAAGACTGCATCGGCCTGATG GATAGAACTCCCCTGATTGCAGCTGGAGTAATTGGTGGGCTCTTCATTCTGGTCATTGTGGGTCTGACATTTGCTGTTTATGTTAGAAGG AAGAGCATCAAAAAGAAAAGAGCCTTGAGAAGATTCTTGGAAACAGAGTTGGTGGAACCATTAACTCCCAGTGGCACAGCACCCAATCAA GCTCAACTTCGTATTTTGAAAGAAACTGAGCTGAAGAGGGTAAAAGTCCTTGGCTCAGGTGCTTTTGGAACGGTTTATAAAGGTATTTGG GTACCTGAAGGAGAAACTGTGAAGATTCCTGTGGCTATTAAGATTCTTAATGAGACAACTGGTCCCAAGGCAAATGTGGAGTTCATGGAT GAAGCTCTGATCATGGCAAGTATGGATCATCCACACCTAGTCCGGTTGCTGGGTGTGTGTCTGAGCCCAACCATCCAGCTGGTTACTCAA CTTATGCCCCATGGCTGCCTGTTGGAGTATGTCCACGAGCACAAGGATAACATTGGATCACAACTGCTGCTTAACTGGTGTGTCCAGATA GCTAAGGGAATGATGTACCTGGAAGAAAGACGACTCGTTCATCGGGATTTGGCAGCCCGTAATGTCTTAGTGAAATCTCCAAACCATGTG AAAATCACAGATTTTGGGCTAGCCAGACTCTTGGAAGGAGATGAAAAAGAGTACAATGCTGATGGAGGAAAGATGCCAATTAAATGGATG GCTCTGGAGTGTATACATTACAGGAAATTCACCCATCAGAGTGACGTTTGGAGCTATGGAGTTACTATATGGGAACTGATGACCTTTGGA GGAAAACCCTATGATGGAATTCCAACGCGAGAAATCCCTGATTTATTAGAGAAAGGAGAACGTTTGCCTCAGCCTCCCATCTGCACTATT GACGTTTACATGGTCATGGTCAAATGTTGGATGATTGATGCTGACAGTAGACCTAAATTTAAGGAACTGGCTGCTGAGTTTTCAAGGATG GCTCGAGACCCTCAAAGATACCTAGTTATTCAGGGTGATGATCGTATGAAGCTTCCCAGTCCAAATGACAGCAAGTTCTTTCAGAATCTC TTGGATGAAGAGGATTTGGAAGATATGATGGATGCTGAGGAGTACTTGGTCCCTCAGGCTTTCAACATCCCACCTCCCATCTATACTTCC AGAGCAAGAATTGACTCGAATAGGAGTGAAATTGGACACAGCCCTCCTCCTGCCTACACCCCCATGTCAGGAAACCAGTTTGTATACCGA GATGGAGGTTTTGCTGCTGAACAAGGAGTGTCTGTGCCCTACAGAGCCCCAACTAGCACAATTCCAGAAGCTCCTGTGGCACAGGGTGCT ACTGCTGAGATTTTTGATGACTCCTGCTGTAATGGCACCCTACGCAAGCCAGTGGCACCCCATGTCCAAGAGGACAGTAGCACCCAGAGG TACAGTGCTGACCCCACCGTGTTTGCCCCAGAACGGAGCCCACGAGGAGAGCTGGATGAGGAAGGTTACATGACTCCTATGCGAGACAAA CCCAAACAAGAATACCTGAATCCAGTGGAGGAGAACCCTTTTGTTTCTCGGAGAAAAAATGGAGACCTTCAAGCATTGGATAATCCCGAA TATCACAATGCATCCAATGGTCCACCCAAGGCCGAGGATGAGTATGTGAATGAGCCACTGTACCTCAACACCTTTGCCAACACCTTGGGA AAAGCTGAGTACCTGAAGAACAACATACTGTCAATGCCAGAGAAGGCCAAGAAAGCGTTTGACAACCCTGACTACTGGAACCACAGCCTG CCACCTCGGAGCACCCTTCAGCACCCAGACTACCTGCAGGAGTACAGCACAAAATATTTTTATAAACAGAATGGGCGGATCCGGCCTATT GTGGCAGAGAATCCTGAATACCTCTCTGAGTTCTCCCTGAAGCCAGGCACTGTGCTGCCGCCTCCACCTTACAGACACCGGAATACTGTG >8762_8762_2_B4GALT5-ERBB4_B4GALT5_chr20_48330113_ENST00000371711_ERBB4_chr2_212812341_ENST00000402597_length(amino acids)=1202AA_BP= MPLENLRIIRGTKLYEDRYALAIFLNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVSTNGSSGC GRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLE HNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGNL IFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAG NIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFREF ENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGANSFIFKYADPDRECHPCHPNCTQGCIGSSIEDCIGL MDRTPLIAAGVIGGLFILVIVGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGI WVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQ IAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTF GGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPNDSKFFQN LLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRARIDSNRSEIGHSPPPAYTPMSGNQFVYRDGGFAAEQGVSVPYRAPTSTIPEAPVAQG ATAEIFDDSCCNGTLRKPVAPHVQEDSSTQRYSADPTVFAPERSPRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSRRKNGDLQALDNP EYHNASNGPPKAEDEYVNEPLYLNTFANTLGKAEYLKNNILSMPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRP -------------------------------------------------------------- >8762_8762_3_B4GALT5-ERBB4_B4GALT5_chr20_48330113_ENST00000371711_ERBB4_chr2_212812341_ENST00000436443_length(transcript)=11842nt_BP=303nt ATGTGGCCCGGCCCGCGACGGCCGGCGGCTGGGAGCGGCGAGGCGGCGGCGGCGGCGAGTGGCGGCCCGCGAGGCCCGGGAGGCGGTGGC CGAGGCCCAGGCGGTGGCGGCGGCGGCCCAGGAGGCGGCGGACGGGGAGCTGCGGGAGCAGGCCCGGCCTGGCTCTCTAGCGGCCGCCTG GCTGCAGCATGCGCGCCCGCCGGGGGCTGCTGCGGCTGCCGCGCCGCTCGCTGCTCGCCGCGCTCTTCTTCTTTTCTCTCTCGTCCTCGC TGCTGTACTTCGTCTATGTGGCGCCCGGCATAGTCTGTTCGAGAAGTCACAGGCTACGTGTTAGTGGCTCTTAATCAGTTTCGTTACCTG CCTCTGGAGAATTTACGCATTATTCGTGGGACAAAACTTTATGAGGATCGATATGCCTTGGCAATATTTTTAAACTACAGAAAAGATGGA AACTTTGGACTTCAAGAACTTGGATTAAAGAACTTGACAGAAATCCTAAATGGTGGAGTCTATGTAGACCAGAACAAATTCCTTTGTTAT GCAGACACCATTCATTGGCAAGATATTGTTCGGAACCCATGGCCTTCCAACTTGACTCTTGTGTCAACAAATGGTAGTTCAGGATGTGGA CGTTGCCATAAGTCCTGTACTGGCCGTTGCTGGGGACCCACAGAAAATCATTGCCAGACTTTGACAAGGACGGTGTGTGCAGAACAATGT GACGGCAGATGCTACGGACCTTACGTCAGTGACTGCTGCCATCGAGAATGTGCTGGAGGCTGCTCAGGACCTAAGGACACAGACTGCTTT GCCTGCATGAATTTCAATGACAGTGGAGCATGTGTTACTCAGTGTCCCCAAACCTTTGTCTACAATCCAACCACCTTTCAACTGGAGCAC AATTTCAATGCAAAGTACACATATGGAGCATTCTGTGTCAAGAAATGTCCACATAACTTTGTGGTAGATTCCAGTTCTTGTGTGCGTGCC TGCCCTAGTTCCAAGATGGAAGTAGAAGAAAATGGGATTAAAATGTGTAAACCTTGCACTGACATTTGCCCAAAAGCTTGTGATGGCATT GGCACAGGATCATTGATGTCAGCTCAGACTGTGGATTCCAGTAACATTGACAAATTCATAAACTGTACCAAGATCAATGGGAATTTGATC TTTCTAGTCACTGGTATTCATGGGGACCCTTACAATGCAATTGAAGCCATAGACCCAGAGAAACTGAACGTCTTTCGGACAGTCAGAGAG ATAACAGGTTTCCTGAACATACAGTCATGGCCACCAAACATGACTGACTTCAGTGTTTTTTCTAACCTGGTGACCATTGGTGGAAGAGTA CTCTATAGTGGCCTGTCCTTGCTTATCCTCAAGCAACAGGGCATCACCTCTCTACAGTTCCAGTCCCTGAAGGAAATCAGCGCAGGAAAC ATCTATATTACTGACAACAGCAACCTGTGTTATTATCATACCATTAACTGGACAACACTCTTCAGCACAATCAACCAGAGAATAGTAATC CGGGACAACAGAAAAGCTGAAAATTGTACTGCTGAAGGAATGGTGTGCAACCATCTGTGTTCCAGTGATGGCTGTTGGGGACCTGGGCCA GACCAATGTCTGTCGTGTCGCCGCTTCAGTAGAGGAAGGATCTGCATAGAGTCTTGTAACCTCTATGATGGTGAATTTCGGGAGTTTGAG AATGGCTCCATCTGTGTGGAGTGTGACCCCCAGTGTGAGAAGATGGAAGATGGCCTCCTCACATGCCATGGACCGGGTCCTGACAACTGT ACAAAGTGCTCTCATTTTAAAGATGGCCCAAACTGTGTGGAAAAATGTCCAGATGGCTTACAGGGGGCAAACAGTTTCATTTTCAAGTAT GCTGATCCAGATCGGGAGTGCCACCCATGCCATCCAAACTGCACCCAAGGGTGTAACGGTCCCACTAGTCATGACTGCATTTACTACCCA TGGACGGGCCATTCCACTTTACCACAACATGCTAGAACTCCCCTGATTGCAGCTGGAGTAATTGGTGGGCTCTTCATTCTGGTCATTGTG GGTCTGACATTTGCTGTTTATGTTAGAAGGAAGAGCATCAAAAAGAAAAGAGCCTTGAGAAGATTCTTGGAAACAGAGTTGGTGGAACCA TTAACTCCCAGTGGCACAGCACCCAATCAAGCTCAACTTCGTATTTTGAAAGAAACTGAGCTGAAGAGGGTAAAAGTCCTTGGCTCAGGT GCTTTTGGAACGGTTTATAAAGGTATTTGGGTACCTGAAGGAGAAACTGTGAAGATTCCTGTGGCTATTAAGATTCTTAATGAGACAACT GGTCCCAAGGCAAATGTGGAGTTCATGGATGAAGCTCTGATCATGGCAAGTATGGATCATCCACACCTAGTCCGGTTGCTGGGTGTGTGT CTGAGCCCAACCATCCAGCTGGTTACTCAACTTATGCCCCATGGCTGCCTGTTGGAGTATGTCCACGAGCACAAGGATAACATTGGATCA CAACTGCTGCTTAACTGGTGTGTCCAGATAGCTAAGGGAATGATGTACCTGGAAGAAAGACGACTCGTTCATCGGGATTTGGCAGCCCGT AATGTCTTAGTGAAATCTCCAAACCATGTGAAAATCACAGATTTTGGGCTAGCCAGACTCTTGGAAGGAGATGAAAAAGAGTACAATGCT GATGGAGGAAAGATGCCAATTAAATGGATGGCTCTGGAGTGTATACATTACAGGAAATTCACCCATCAGAGTGACGTTTGGAGCTATGGA GTTACTATATGGGAACTGATGACCTTTGGAGGAAAACCCTATGATGGAATTCCAACGCGAGAAATCCCTGATTTATTAGAGAAAGGAGAA CGTTTGCCTCAGCCTCCCATCTGCACTATTGACGTTTACATGGTCATGGTCAAATGTTGGATGATTGATGCTGACAGTAGACCTAAATTT AAGGAACTGGCTGCTGAGTTTTCAAGGATGGCTCGAGACCCTCAAAGATACCTAGTTATTCAGGGTGATGATCGTATGAAGCTTCCCAGT CCAAATGACAGCAAGTTCTTTCAGAATCTCTTGGATGAAGAGGATTTGGAAGATATGATGGATGCTGAGGAGTACTTGGTCCCTCAGGCT TTCAACATCCCACCTCCCATCTATACTTCCAGAGCAAGAATTGACTCGAATAGGAACCAGTTTGTATACCGAGATGGAGGTTTTGCTGCT GAACAAGGAGTGTCTGTGCCCTACAGAGCCCCAACTAGCACAATTCCAGAAGCTCCTGTGGCACAGGGTGCTACTGCTGAGATTTTTGAT GACTCCTGCTGTAATGGCACCCTACGCAAGCCAGTGGCACCCCATGTCCAAGAGGACAGTAGCACCCAGAGGTACAGTGCTGACCCCACC GTGTTTGCCCCAGAACGGAGCCCACGAGGAGAGCTGGATGAGGAAGGTTACATGACTCCTATGCGAGACAAACCCAAACAAGAATACCTG AATCCAGTGGAGGAGAACCCTTTTGTTTCTCGGAGAAAAAATGGAGACCTTCAAGCATTGGATAATCCCGAATATCACAATGCATCCAAT GGTCCACCCAAGGCCGAGGATGAGTATGTGAATGAGCCACTGTACCTCAACACCTTTGCCAACACCTTGGGAAAAGCTGAGTACCTGAAG AACAACATACTGTCAATGCCAGAGAAGGCCAAGAAAGCGTTTGACAACCCTGACTACTGGAACCACAGCCTGCCACCTCGGAGCACCCTT CAGCACCCAGACTACCTGCAGGAGTACAGCACAAAATATTTTTATAAACAGAATGGGCGGATCCGGCCTATTGTGGCAGAGAATCCTGAA TACCTCTCTGAGTTCTCCCTGAAGCCAGGCACTGTGCTGCCGCCTCCACCTTACAGACACCGGAATACTGTGGTGTAAGCTCAGTTGTGG TTTTTTAGGTGGAGAGACACACCTGCTCCAATTTCCCCACCCCCCTCTCTTTCTCTGGTGGTCTTCCTTCTACCCCAAGGCCAGTAGTTT TGACACTTCCCAGTGGAAGATACAGAGATGCAATGATAGTTATGTGCTTACCTAACTTGAACATTAGAGGGAAAGACTGAAAGAGAAAGA TAGGAGGAACCACAATGTTTCTTCATTTCTCTGCATGGGTTGGTCAGGAGAATGAAACAGCTAGAGAAGGACCAGAAAATGTAAGGCAAT GCTGCCTACTATCAAACTAGCTGTCACTTTTTTTCTTTTTCTTTTTCTTTCTTTGTTTCTTTCTTCCTCTTCTTTTTTTTTTTTTTTTTT AAAGCAGATGGTTGAAACACCCATGCTATCTGTTCCTATCTGCAGGAACTGATGTGTGCATATTTAGCATCCCTGGAAATCATAATAAAG TTTCCATTAGAACAAAAGAATAACATTTTCTATAACATATGATGGTGTCTGAAATTGAGAATCCAGTTTCTTTCCCCAGCAGTTTCTGTC CTAGCAAGTAAGAATGGCCAACTCAACTTTCATAATTTAAAAATCTCCATTAAAGTTATAACTAGTAATTATGTTTTCAACACTTTTTGG TTTTTTTCATTTTGTTTTGCTCTGACCGATTCCTTTATATTTGCTCCCCTATTTTTGGCTTTAATTTCTAATTGCAAAGATGTTTACATC AAAGCTTCTTCACAGAATTTAAGCAAGAAATATTTTAATATAGTGAAATGGCCACTACTTTAAGTATACAATCTTTAAAATAAGAAAGGG AGGCTAATATTTTTCATGCTATCAAATTATCTTCACCCTCATCCTTTACATTTTTCAACATTTTTTTTTCTCCATAAATGACACTACTTG ATAGGCCGTTGGTTGTCTGAAGAGTAGAAGGGAAACTAAGAGACAGTTCTCTGTGGTTCAGGAAAACTACTGATACTTTCAGGGGTGGCC CAATGAGGGAATCCATTGAACTGGAAGAAACACACTGGATTGGGTATGTCTACCTGGCAGATACTCAGAAATGTAGTTTGCACTTAAGCT GTAATTTTATTTGTTCTTTTTCTGAACTCCATTTTGGATTTTGAATCAAGCAATATGGAAGCAACCAGCAAATTAACTAATTTAAGTACA TTTTTAAAAAAAGAGCTAAGATAAAGACTGTGGAAATGCCAAACCAAGCAAATTAGGAACCTTGCAACGGTATCCAGGGACTATGATGAG AGGCCAGCACATTATCTTCATATGTCACCTTTGCTACGCAAGGAAATTTGTTCAGTTCGTATACTTCGTAAGAAGGAATGCGAGTAAGGA TTGGCTTGAATTCCATGGAATTTCTAGTATGAGACTATTTATATGAAGTAGAAGGTAACTCTTTGCACATAAATTGGTATAATAAAAAGA AAAACACAAACATTCAAAGCTTAGGGATAGGTCCTTGGGTCAAAAGTTGTAAATAAATGTGAAACATCTTCTCATGCAATTATTTTATTA TCCAACACACTAATCTTTTGATACTTTATATAATTCCCTTTCTTCATATACTGCATCCAGTACTAGAACCATCATTATTATGTATCATTT TGAAAGAATACCTGATGAGATGAAGGATGAGAACAAATGACAGAGATGAGTCTCCAAGTAAAGGGGGCCTCACATCAATAATTAGGAAAC TTAGATATAAGTCGCCCTTTTCTGAAAATTCTACCCCAAGTCATTTAGATTTTTAAAAAATATTTCTAATGTTAAAATATTGGGACCAAA TTAGAATCAATAGTATAAGATTAATTAATTAGAGTAAAAATATCTATTAAGGCAGAGAAAGTTTAGAGAAAAAAATCCAAAGAAATTTGT GTTTCTTCCTATTCTGAACAAGTAAATCCATCCATCCATCCATCCAAACCTCCTTTATCTAACTGTGTCTACTAAAAGCACCATGTTTTG TGGGGAACACTCAGATAAATGGAATATCATCCTCAACTTCAAAATTCTATGATCTAGGAGATTTAATTAAAATGACATTTTAATTTTTCT ATGCGTTCCAACAATCAGATTGCATAGTCTCTTTTGTGAATAGCTGTCATATAATCAGTTGTACTGTAAGATATCTCCTTTAAACTCATT TGGGATATAAGTTAAACATCCTTCAAATTGTTGATGTTGACAAACAGGATAATTTCAATAATATTATTCAAACATAAACTGGTCTAGGAG AATATTGCATCACTGACTAATTAGCCTATCTAGAGTCTAACTTCACCATTAAACCAAAAGCAGATGGTGGTCCTTGGCCAAGAATATTGG AGACATTGGAGTTGGTTTTTTTCTAAGCTATAAGAAGTGAGGCGAGCTGAAAAAGTATGGTAGAGCAGGAGAAGGGTTTGTGAGATTCCT TCTAGTGAAGTTCACCCTCAAACTTTTCAGGGGTAAAGACACAGAGTGATTCAGGGGCCACAATCTAATAGCTCAGGGCTCTCCTATCCA TTCAGAGAAGTCTCTAGGAAAAGGGATCTCATATCAGTACTTATGAAAAATTGAATATAAGCCTCCCTTTCTAAATAAATCTGCATCGAG TCATCACAGCCCTCTTTTTGGATACTATACCTTGATTTTTTTTTTCTGATTTACAATATGCATATGGTTTCTACTGGGCTATAGAAAGCA GAATCACTCATTTTGGAGAAGGAAAAAATGAATAGTTAAAACAAACTTTTAACTGTTAAGGTAACAGAAATGTATTTAGTGAATGTCTCT TTCCTCCTAAGAACACAAGACTTCTACATGTTGGGTAATACCTAGAGATGCATGTAGGAATAATCCAAAATGACCCAAATGCTTTATAAT AGCACCACTTTATAATTCTTTTGAATGATTTCTGTAGTATATAATTGACTTCAGTTGTTTGAGTGTTTTTTGTTTTATTTTTGTCCCCCC TGGGAAAACATATTTCAGCATGTATAAGAGGGAGAAAAAAAGTTTCATTCCTTCCAGAGAATAACTTATTTAGTCCAGTAGGGTAGAATT TTAAAATGTCAGTTAAAGTCTTCAAAGTGCTTGGGGGGATATCAGATTCCAGAGGCCAATTGTAGCAATTGAAATTTGCAGAATCAATTA TGTAAATCTGAGACAAATTAGTATTAAAATTACACGGAGTATATTTTTTAAATCACCCAACTTTGTAGATTATACCTATTTTGGGCAGGT ATGGAAAAATTTTGCAGTTAAATGATTGCCTAAAGAAAGTGGTAAACAGGTGAGGAAAGATGGCCTCTGATCTAGGATAGATCCAGAACC ACAAAGCATCTGCACCACAAAAGGTGTTAGACTACCAAGCAGCTCCTGGTTTTCTGCATAGTATTAGTAGCACAGCTTAGGATGAGAATC CTTTCTCCAGTAACATTCTTAAAATAGCATGAAAAACAACGCAAAACTCAAATTTCTATTAAAACACACAAACTAAAATCAAGTGATTCT TTTTTGTAGATTAGGGAGAAGGACTGAATATCTAATTTAAGAGAAGGAATAGTGTTTAAGTGTTATAGTGTGTGAGCTAATACCTTCTAA AGGAAAGACATGGCATGAAGATTGTGCATACTTACAATGCTAAGGAAAAATCAAGAAAAGGACTGTGTGAGGCTCTGCTACTAGATGAAG TTGGAAGGACTATTAATGTGCTTCTTGAAGTATCAAAAATGAAAAGAAAATTAAAATTGTTTAAGCCTGACAGGGAAGGATGTAAATACA AGTTTTTCTAGAGCTCTCTAACCTTTATTTCAAAACTGGAATTATTCATCCATCTGTAATTGTTGATAATTTAACTAGTATATGTAGTTC ATAAGGTAATAGAAAAGGTGATCATGAAAGCATGTATATAACTGGACAGAACCACGATAATGCTATAAGATGTAGATTTAGTTAGGTTAT CAGATGTTAAATGATTTTAATATTATTAAATAAATCAAACTAGAAAACTAACCACAAGTATAATGTAACAAAGTTAAATGCAGGATATAA AAATGTAGGATGGATTTTGCATAGTAAAAAGATAAGTTTGCCATTTAAAATTGTTGTTTGTTGGGTTTAGCTGAAAGTAGGCATATATGG TTCCACTTGGGAAAACTTGCTTTAAAGCATTACAATGAACAATTTTTTCTCATTCTCTTATTCCTTTATCACTTTTTAAATGTAAAGAAA ATTGTATTTATTTATTTTTTTAAATAAACACCACCTTGCAGAATTTAATAGGCAAACATGTTACATATGACTAAGTAAGGGTCTTCAAGA TGAAGTAAAGAAAATGTAAATGTTCTATTACCTTATGCAGAGACAAAAAAAAAAAGGAGTGGTGTCATTTAGCTAGCAAACAAACAAAAT ACAGTTAATTGGTGATATGTCCTTTCTTTTCTCACTATGCCCTCTTGCCTCCAAAAATGACAACAAAGAATCACAATTTTTCTGATAAAT AAATGCTAAACCAAGCGTTTCAAACTATTGCATTGCCATTCTTTTGGACTTTAGTTATTAGAATGATGATTGTTATAGGGCAAATGAGAA ATCCATGTGCATCAGCTTCTAGTTGTTAAAAAAACCAGATAAATTAACTTCTACTGTATACTGTGGGCAGAGGATCCTAGAGCTGATCCT ACAACATCAGCTTCTAGTTGTTAAAAAAAAAAAAAGAAACAGATAAATTAACTTCTACTGTATATACTGTGGGCAGAGGATCTTACTGTG CCTCTGTTTGTGTACATGGACTTCGGTGTGTATCAGTTTGAAGGACAGCCTTGCCCCATGTAAACATATAAATGCAGATTGGTATCGCCT GGTTGCTATTTGCTTAAGAACAAATATTATACAGATGAGATCAGGCATAATTTTAAAAGATCATTATCAGTGGAGACCTCATTATTACTG ATATTACAATGGGGCCAGTTTTTATACTTCTGGGTAGAATTAATAAAATTTTTCTGATCCCAGAGATCTGAGTTCTCTCTGCAGTTGGAA ACAAGAAGCTGTTGTGGGCATTGTGTCGGGCCAGGGGCCCTTGTGTTTGTGTGGGCAAATATCTTTTAGCAGTGTGAGCTGCTTTTTTCT TTTCATTAAAAGTCTCTCTAAAATAATAGAAATTTCAGATACTCGGTTCAAGTCTCACTGATTTTGTAGAGGTCCAAAAATGTAGGATCT GTCACTTTTGCAGGCCCCTGCCTCACCTAATTCCTGGCCAGGTGACATTTTGGGCAGAAGTAAATGCTTCTATAGTCACAAGCTAAAATG ACTCTAAGCCCCAATTTCACGGGGGGTATTCACATGCTTCCTCTGGAAAATACTCTTTGACAGTCAGCTTTGCAAGTAAGTGATTACCTT GTTAGGAATCAAAGAAAAATGTATTTCTCTCTGACCTTTAGAGGAAAATAGAATCCTTCCCTTTTTTGCCCATTGACACAACTGGCACTG CTCTCTTCCCTTTCTACCACCCTGGTTCAAAGTAGTCCCCCGATGCTGTCCTGTTCCTTTCTTAAGCCATAGTGGATCTCTGAGATCCTA CACCCCACTTTGTGAAACACTGACTTCATCTTTGCCCTCGAATGCCTGATTTTTTCATAAGAGATTCTAGCAATTTGGACACTGTTTAAG TGAACTATCAAACTACCGCATAGAGAATATTTAAGCTATTAAAATTATGGTTTCCCATGAAGATCAATTCTCTGTGTCCTTCCCTATAGG AATTTGAGACGAGTTAGCCCTGTGATGAATCTTGAAACTCACATATGTCCACATACACTTGGTAGAACTTCGATTTAATCTTTACATAAA AGCTGTACATATAACCAAGAAGTTATTTTTGCCAGTAAATTAACTTATTTGCTTTATTCATCTTATTTGGTTCCTAATCGTAAATATTTT GTAGCTGCTGTAAATTTTTTTCTCCCAAATGAGGAGTCTTATTATCATAAAGGTAAAGGCTATTCAGCTTTGATAACCACCTGCAATTCT TTTTTGGATCATTCATCCATCTAACAAATACATAATGAGGACAGTTCATGTTAATGAAAATCCATGTTGTTTAATAGAATGCCATCCTTT ACCTACTTTTGCTCTTTATGGACGTTTTTCTTTTCATGCTCTAGTGAGCTTTCCCTATATCATGAGAAGTGGTTATATTTGTGCAAATAT ACAAATATAGGAAAACAAAGATTCATACCTGTAGGCAATAGTCTAACTTGTCCAAACCACTTTGCCTTTACTGCTATTTTTATCCCCAAT GCGTAGATATTTCCCCCAGGCCTATAGCCTTTGTGAAGGAAAGCAAATCATACCTCCTGTATATTGACACGAATCTGGTTTTCAAATGTC ATTTCCAGATTTTTTAGTTAATTGGGGGTTGTCCTTTTCCCTTAATGTGAGAGTCATTTTCCTGTATATTTCTGGATCTCTCAGGGGCTG GGAGGGGGGAGTGAGGGGACTACAACCATAGCACTCCAAGAACCCTTTTGGGATTACTCCAGTAATCAACTACGAAAGTTATTTTCTAAA TGTAGATATGTAAGGTGTTCTTTTAAAGTAAGGTACTTTGAAATATGTAGCATAAACTGGTACTGCTGTTAAATGGGTCGATTATTAAAC GGAGCAGCTGTGTGAGGGCAGCTAACTTTGAATGCCTGTCTCCCTGGCTGGTGTGTCTCCTTCTCATGTTGAGAGCACCAGGGATTGCGT GGCTGCATGCTGAAACCGCATTTTCCCATGGTGTATGACTAGTTCATCTCTTTCTTGAGCACCATTACAAGAAGATCAAATGAAAATGAG ATCAATGTGGAAGACAATTCATAGCACAAAAAAAGTCATCTTAAATCTACTCTCAAACATTCATCTTATACATGCATCAAAGTAATTTAC TGACATCAGTTTGGGTGAGAGAGGGAGTCACTTTACTGAAAAGGCAGAGGCTTAAGGTGTATACATTTGTACTCACTTCCTTATTTTCTT AACTTGTAAGCAGAAAACAAGCCCTCTCTCTTGTGAAGTATCTTCAAAGGATTGGGGTGCAAAAATACCTTGCTGGTAAGCCATCAATGT TTTATTTAAATCCCTGCATTCAAAGTTAGCTGCCTTTTTGAAATAAACAAACAAAAAATACTACTGTATGTTTGAAAATGTGAATAGTAT TTTTATAGCTTGTTAAAGACATGGCTAGTTGCATTTGTAAATAAGTATAATGTTGCTTTGATTTTCTTTTGTGGACATCTTTATTTGGAA CATAATTGTCTTTAGGGTTGATTTGTATATAAGTAATTGGCCTGTGATTGTTTCTTTTTTGGTTGGAAGTTATCATTTTGACATTACTTG TGATTCTGTGTTCAGCACTATTGTGATGTGTTCAACCTCTGCACTCGCTTACACAATAGGATATGCCAATTGTGTGTGGTGTAATGTTAT TTTGATTTTTTTCCATGTTATTGATGAAGGATCATGCACCTAACACATACTAACTTTTTTAATGTTAGGCATATTTTTAGTATACTTTCT CTTATTCTTTCTTCTCCTCCAACCTTTTACCCATCCTCCTTCCTTTCCCTCATTCCTGTTGTTATTTGAGAATGAGGGAGAAACAGTATT TTACATTTATGTAATTAGGCTTTTCCGTTAGTTCTCAAGGATCCTCTTTTGGCTCTTGGGAAAGAATTGTACCTGTACAAGGCAATTATA GAATGCGAACTGCTTTGCCTCATTCCATACTGATCATCCCAGCTGAACAATTTGAAAACTGTTCTGCCTTTTTGTTACATGAATCTGTCA >8762_8762_3_B4GALT5-ERBB4_B4GALT5_chr20_48330113_ENST00000371711_ERBB4_chr2_212812341_ENST00000436443_length(amino acids)=1196AA_BP= MPLENLRIIRGTKLYEDRYALAIFLNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVSTNGSSGC GRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLE HNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGNL IFLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYSGLSLLILKQQGITSLQFQSLKEISAG NIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFREF ENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGANSFIFKYADPDRECHPCHPNCTQGCNGPTSHDCIYY PWTGHSTLPQHARTPLIAAGVIGGLFILVIVGLTFAVYVRRKSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGS GAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIG SQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSY GVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLP SPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRARIDSNRNQFVYRDGGFAAEQGVSVPYRAPTSTIPEAPVAQGATAEIF DDSCCNGTLRKPVAPHVQEDSSTQRYSADPTVFAPERSPRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHNAS NGPPKAEDEYVNEPLYLNTFANTLGKAEYLKNNILSMPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVAENP -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for B4GALT5-ERBB4 |
Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
Hgene | Hgene's interactors | Tgene | Tgene's interactors |
- Retained PPIs in in-frame fusion. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
- Lost PPIs in in-frame fusion. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
- Retained PPIs, but lost function due to frame-shift fusion. |
Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for B4GALT5-ERBB4 |
Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Tgene | ERBB4 | Q15303 | DB08916 | Afatinib | Inhibitor | Small molecule | Approved |
Tgene | ERBB4 | Q15303 | DB08916 | Afatinib | Inhibitor | Small molecule | Approved |
Tgene | ERBB4 | Q15303 | DB12010 | Fostamatinib | Inhibitor | Small molecule | Approved|Investigational |
Tgene | ERBB4 | Q15303 | DB12010 | Fostamatinib | Inhibitor | Small molecule | Approved|Investigational |
Tgene | ERBB4 | Q15303 | DB12267 | Brigatinib | Inhibitor | Small molecule | Approved|Investigational |
Tgene | ERBB4 | Q15303 | DB12267 | Brigatinib | Inhibitor | Small molecule | Approved|Investigational |
Tgene | ERBB4 | Q15303 | DB15035 | Zanubrutinib | Inhibitor | Small molecule | Approved|Investigational |
Tgene | ERBB4 | Q15303 | DB15035 | Zanubrutinib | Inhibitor | Small molecule | Approved|Investigational |
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Related Diseases for B4GALT5-ERBB4 |
Diseases associated with fusion partners. (DisGeNet 4.0) |
Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Hgene | B4GALT5 | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
Hgene | B4GALT5 | C0087031 | Juvenile-Onset Still Disease | 1 | CTD_human |
Hgene | B4GALT5 | C3495559 | Juvenile arthritis | 1 | CTD_human |
Hgene | B4GALT5 | C3714758 | Juvenile psoriatic arthritis | 1 | CTD_human |
Hgene | B4GALT5 | C4552091 | Polyarthritis, Juvenile, Rheumatoid Factor Negative | 1 | CTD_human |
Hgene | B4GALT5 | C4704862 | Polyarthritis, Juvenile, Rheumatoid Factor Positive | 1 | CTD_human |
Tgene | C0005586 | Bipolar Disorder | 5 | PSYGENET | |
Tgene | C0036341 | Schizophrenia | 4 | PSYGENET | |
Tgene | C0004238 | Atrial Fibrillation | 2 | CTD_human | |
Tgene | C0235480 | Paroxysmal atrial fibrillation | 2 | CTD_human | |
Tgene | C2585653 | Persistent atrial fibrillation | 2 | CTD_human | |
Tgene | C3468561 | familial atrial fibrillation | 2 | CTD_human | |
Tgene | C0002736 | Amyotrophic Lateral Sclerosis | 1 | ORPHANET | |
Tgene | C0007114 | Malignant neoplasm of skin | 1 | CTD_human | |
Tgene | C0016978 | gallbladder neoplasm | 1 | CTD_human | |
Tgene | C0025202 | melanoma | 1 | CGI;CTD_human | |
Tgene | C0037286 | Skin Neoplasms | 1 | CTD_human | |
Tgene | C0153452 | Malignant neoplasm of gallbladder | 1 | CTD_human | |
Tgene | C3715155 | AMYOTROPHIC LATERAL SCLEROSIS 19 | 1 | CTD_human;GENOMICS_ENGLAND;UNIPROT |