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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:MUC16-RNASEH2B (FusionGDB2 ID:HG94025TG79621) |
Fusion Gene Summary for MUC16-RNASEH2B |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MUC16-RNASEH2B | Fusion gene ID: hg94025tg79621 | Hgene | Tgene | Gene symbol | MUC16 | RNASEH2B | Gene ID | 94025 | 79621 |
| Gene name | mucin 16, cell surface associated | ribonuclease H2 subunit B | |
| Synonyms | CA125 | AGS2|DLEU8 | |
| Cytomap | ('MUC16')('RNASEH2B') 19p13.2 | 13q14.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | mucin-16CA125 ovarian cancer antigenmucin-16 long isoformmucin-16 short isoformovarian cancer-related tumor marker CA125ovarian carcinoma antigen CA125 | ribonuclease H2 subunit BAicardi-Goutieres syndrome 2 proteinRNase H2 subunit Bdeleted in lymphocytic leukemia 8ribonuclease HI subunit B | |
| Modification date | 20200329 | 20200320 | |
| UniProtAcc | . | . | |
| Ensembl transtripts involved in fusion gene | ENST00000397910, ENST00000380951, ENST00000596956, | ||
| Fusion gene scores | * DoF score | 12 X 24 X 4=1152 | 11 X 8 X 8=704 |
| # samples | 21 | 12 | |
| ** MAII score | log2(21/1152*10)=-2.45567948377619 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(12/704*10)=-2.55254102302878 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: MUC16 [Title/Abstract] AND RNASEH2B [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | MUC16(9080451)-RNASEH2B(51501543), # samples:2 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | RNASEH2B | GO:0006401 | RNA catabolic process | 21177858 |
| Fusion gene breakpoints across MUC16 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across RNASEH2B (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | OV | TCGA-09-0367-01A | MUC16 | chr19 | 9080451 | - | RNASEH2B | chr13 | 51501543 | + |
| ChimerDB4 | OV | TCGA-09-0367 | MUC16 | chr19 | 9080450 | - | RNASEH2B | chr13 | 51501542 | + |
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Fusion Gene ORF analysis for MUC16-RNASEH2B |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000397910 | ENST00000495244 | MUC16 | chr19 | 9080451 | - | RNASEH2B | chr13 | 51501543 | + |
| 5CDS-intron | ENST00000397910 | ENST00000495244 | MUC16 | chr19 | 9080450 | - | RNASEH2B | chr13 | 51501542 | + |
| In-frame | ENST00000397910 | ENST00000336617 | MUC16 | chr19 | 9080451 | - | RNASEH2B | chr13 | 51501543 | + |
| In-frame | ENST00000397910 | ENST00000336617 | MUC16 | chr19 | 9080450 | - | RNASEH2B | chr13 | 51501542 | + |
| In-frame | ENST00000397910 | ENST00000422660 | MUC16 | chr19 | 9080451 | - | RNASEH2B | chr13 | 51501543 | + |
| In-frame | ENST00000397910 | ENST00000422660 | MUC16 | chr19 | 9080450 | - | RNASEH2B | chr13 | 51501542 | + |
| intron-3CDS | ENST00000380951 | ENST00000336617 | MUC16 | chr19 | 9080451 | - | RNASEH2B | chr13 | 51501543 | + |
| intron-3CDS | ENST00000380951 | ENST00000336617 | MUC16 | chr19 | 9080450 | - | RNASEH2B | chr13 | 51501542 | + |
| intron-3CDS | ENST00000380951 | ENST00000422660 | MUC16 | chr19 | 9080451 | - | RNASEH2B | chr13 | 51501543 | + |
| intron-3CDS | ENST00000380951 | ENST00000422660 | MUC16 | chr19 | 9080450 | - | RNASEH2B | chr13 | 51501542 | + |
| intron-3CDS | ENST00000596956 | ENST00000336617 | MUC16 | chr19 | 9080451 | - | RNASEH2B | chr13 | 51501543 | + |
| intron-3CDS | ENST00000596956 | ENST00000336617 | MUC16 | chr19 | 9080450 | - | RNASEH2B | chr13 | 51501542 | + |
| intron-3CDS | ENST00000596956 | ENST00000422660 | MUC16 | chr19 | 9080451 | - | RNASEH2B | chr13 | 51501543 | + |
| intron-3CDS | ENST00000596956 | ENST00000422660 | MUC16 | chr19 | 9080450 | - | RNASEH2B | chr13 | 51501542 | + |
| intron-intron | ENST00000380951 | ENST00000495244 | MUC16 | chr19 | 9080451 | - | RNASEH2B | chr13 | 51501543 | + |
| intron-intron | ENST00000380951 | ENST00000495244 | MUC16 | chr19 | 9080450 | - | RNASEH2B | chr13 | 51501542 | + |
| intron-intron | ENST00000596956 | ENST00000495244 | MUC16 | chr19 | 9080451 | - | RNASEH2B | chr13 | 51501543 | + |
| intron-intron | ENST00000596956 | ENST00000495244 | MUC16 | chr19 | 9080450 | - | RNASEH2B | chr13 | 51501542 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000397910 | MUC16 | chr19 | 9080451 | - | ENST00000336617 | RNASEH2B | chr13 | 51501543 | + | 10950 | 9784 | 99 | 10658 | 3519 |
| ENST00000397910 | MUC16 | chr19 | 9080451 | - | ENST00000422660 | RNASEH2B | chr13 | 51501543 | + | 10986 | 9784 | 99 | 10493 | 3464 |
| ENST00000397910 | MUC16 | chr19 | 9080450 | - | ENST00000336617 | RNASEH2B | chr13 | 51501542 | + | 10950 | 9784 | 99 | 10658 | 3519 |
| ENST00000397910 | MUC16 | chr19 | 9080450 | - | ENST00000422660 | RNASEH2B | chr13 | 51501542 | + | 10986 | 9784 | 99 | 10493 | 3464 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000397910 | ENST00000336617 | MUC16 | chr19 | 9080451 | - | RNASEH2B | chr13 | 51501543 | + | 0.003166562 | 0.9968335 |
| ENST00000397910 | ENST00000422660 | MUC16 | chr19 | 9080451 | - | RNASEH2B | chr13 | 51501543 | + | 0.003624767 | 0.99637526 |
| ENST00000397910 | ENST00000336617 | MUC16 | chr19 | 9080450 | - | RNASEH2B | chr13 | 51501542 | + | 0.003166562 | 0.9968335 |
| ENST00000397910 | ENST00000422660 | MUC16 | chr19 | 9080450 | - | RNASEH2B | chr13 | 51501542 | + | 0.003624767 | 0.99637526 |
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Fusion Genomic Features for MUC16-RNASEH2B |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for MUC16-RNASEH2B |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:9080451/chr13:51501543) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | . |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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Fusion Gene Sequence for MUC16-RNASEH2B |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >55996_55996_1_MUC16-RNASEH2B_MUC16_chr19_9080450_ENST00000397910_RNASEH2B_chr13_51501542_ENST00000336617_length(transcript)=10950nt_BP=9784nt AAGCGTTGCACAATTCCCCCAACCTCCATACATACGGCAGCTCTTCTAGACACAGGTTTTCCCAGGTCAAATGCGGGGACCCCAGCCATA TCTCCCACCCTGAGAAATTTTGGAGTTTCAGGGAGCTCAGAAGCTCTGCAGAGGCCACCCTCTCTGAGGGGATTCTTCTTAGACCTCCAT CCAGAGGCAAATGTTGACCTGTCCATGCTGAAACCCTCAGGCCTTCCTGGGTCATCTTCTCCCACCCGCTCCTTGATGACAGGGAGCAGG AGCACTAAAGCCACACCAGAAATGGATTCAGGACTGACAGGAGCCACCTTGTCACCTAAGACATCTACAGGTGCAATCGTGGTGACAGAA CATACTCTGCCCTTTACTTCCCCAGATAAGACCTTGGCCAGTCCTACATCTTCGGTTGTGGGAAGAACCACCCAGTCTTTGGGGGTGATG TCCTCTGCTCTCCCTGAGTCAACCTCTAGAGGAATGACACACTCCGAGCAAAGAACCAGCCCATCGCTGAGTCCCCAGGTCAATGGAACT CCCTCTAGGAACTACCCTGCTACAAGCATGGTTTCAGGATTGAGTTCCCCAAGGACCAGGACCAGTTCCACAGAAGGAAATTTTACCAAA GAAGCATCTACATACACACTCACTGTAGAGACCACAAGTGGCCCAGTCACTGAGAAGTACACAGTCCCCACTGAGACCTCAACAACTGAA GGTGACAGCACAGAGACCCCCTGGGACACAAGATATATTCCTGTAAAAATCACATCTCCAATGAAAACATTTGCAGATTCAACTGCATCC AAGGAAAATGCCCCAGTGTCTATGACTCCAGCTGAGACCACAGTTACTGACTCACATACTCCAGGAAGGACAAACCCATCATTTGGGACA CTTTATTCTTCCTTCCTTGACCTATCACCTAAAGGGACCCCAAATTCCAGAGGTGAAACAAGCCTGGAACTGATTCTATCAACCACTGGA TATCCCTTCTCCTCTCCTGAACCTGGCTCTGCAGGACACAGCAGAATAAGTACCAGTGCGCCTTTGTCATCATCTGCTTCAGTTCTCGAT AATAAAATATCAGAGACCAGCATATTCTCAGGCCAGAGTCTCACCTCCCCTCTGTCTCCTGGGGTGCCCGAGGCCAGAGCCAGCACAATG CCCAACTCAGCTATCCCTTTTTCCATGACACTAAGCAATGCAGAAACAAGTGCCGAAAGGGTCAGAAGCACAATTTCCTCTCTGGGGACT CCATCAATATCCACAAAGCAGACAGCAGAGACTATCCTTACCTTCCATGCCTTCGCTGAGACCATGGATATACCCAGCACCCACATAGCC AAGACTTTGGCTTCAGAATGGTTGGGAAGTCCAGGTACCCTTGGTGGCACCAGCACTTCAGCGCTGACAACCACATCTCCATCTACCACT TTAGTCTCAGAGGAGACCAACACCCATCACTCCACGAGTGGAAAGGAAACAGAAGGAACTTTGAATACATCTATGACTCCACTTGAGACC TCTGCTCCTGGAGAAGAGTCCGAAATGACTGCCACCTTGGTCCCCACTCTAGGTTTTACAACTCTTGACAGCAAGATCAGAAGTCCATCT CAGGTCTCTTCATCCCACCCAACAAGAGAGCTCAGAACCACAGGCAGCACCTCTGGGAGGCAGAGTTCCAGCACAGCTGCCCACGGGAGC TCTGACATCCTGAGGGCAACCACTTCCAGCACCTCAAAAGCATCATCATGGACCAGTGAAAGCACAGCTCAGCAATTTAGTGAACCCCAG CACACACAGTGGGTGGAGACAAGTCCTAGCATGAAAACAGAGAGACCCCCAGCATCAACCAGTGTGGCAGCCCCTATCACCACTTCTGTT CCCTCAGTGGTCTCTGGCTTCACCACCCTGAAGACCAGCTCCACAAAAGGGATTTGGCTTGAAGAAACATCTGCAGACACACTCATCGGA GAATCCACAGCTGGCCCAACCACCCATCAGTTTGCTGTTCCCACTGGGATTTCAATGACAGGAGGCAGCAGCACCAGGGGAAGCCAGGGC ACAACCCACCTACTCACCAGAGCCACAGCATCATCTGAGACATCCGCAGATTTGACTCTGGCCACGAACGGTGTCCCAGTCTCCGTGTCT CCAGCAGTGAGCAAGACGGCTGCTGGCTCAAGTCCTCCAGGAGGGACAAAGCCATCATATACAATGGTTTCTTCTGTCATCCCTGAGACA TCATCTCTACAGTCCTCAGCTTTCAGGGAAGGAACCAGCCTGGGACTGACTCCATTAAACACTAGACATCCCTTCTCTTCCCCTGAACCA GACTCTGCAGGACACACCAAGATAAGCACCAGCATTCCTCTGTTGTCATCTGCTTCAGTTCTTGAGGATAAAGTGTCAGCGACCAGCACA TTCTCACACCACAAAGCCACCTCATCTATTACCACAGGGACTCCTGAAATCTCAACAAAGACAAAGCCCAGCTCAGCCGTTCTTTCCTCC ATGACCCTAAGCAATGCAGCAACAAGTCCTGAAAGAGTCAGAAATGCAACTTCCCCTCTGACTCATCCATCTCCATCAGGGGAAGAGACA GCAGGGAGTGTCCTCACTCTCAGCACCTCTGCTGAGACTACAGACTCACCTAACATCCACCCAACTGGGACACTGACTTCAGAATCGTCA GAGAGTCCTAGCACTCTCAGCCTCCCAAGTGTCTCTGGAGTCAAAACCACATTTTCTTCATCTACTCCTTCCACTCATCTATTTACTAGT GGAGAAGAAACAGAGGAAACTTCGAATCCATCTGTGTCTCAACCTGAGACTTCTGTTTCCAGAGTAAGGACCACCTTGGCCAGCACCTCT GTCCCTACCCCAGTATTCCCCACCATGGACACCTGGCCTACACGTTCAGCTCAGTTCTCTTCATCCCACCTAGTGAGTGAGCTCAGAGCT ACGAGCAGTACCTCAGTTACAAACTCAACTGGTTCAGCTCTTCCTAAAATATCTCACCTCACTGGGACGGCAACAATGTCACAGACCAAT AGAGACACGTTTAATGACTCTGCTGCACCCCAAAGCACAACTTGGCCAGAGACTAGTCCCAGATTCAAGACAGGGTTACCTTCAGCAACA ACCACTGTTTCAACCTCTGCCACTTCTCTCTCTGCTACTGTAATGGTCTCTAAATTCACTTCTCCAGCAACTAGTTCCATGGAAGCAACT TCTATCAGGGAACCATCAACAACCATCCTCACAACAGAGACCACGAATGGCCCAGGCTCTATGGCTGTGGCTTCTACCAACATCCCAATT GGAAAGGGCTACATTACTGAAGGAAGATTGGACACAAGCCATCTGCCCATTGGAACCACAGCTTCCTCTGAGACATCTATGGATTTTACC ATGGCCAAAGAAAGTGTCTCAATGTCAGTATCTCCATCTCAGTCCATGGATGCTGCTGGCTCAAGCACTCCAGGAAGGACAAGCCAATTC GTTGACACATTTTCTGATGATGTCTATCATTTAACATCCAGAGAAATTACAATACCTAGAGATGGAACAAGCTCAGCTCTGACTCCACAA ATGACTGCAACTCACCCTCCATCTCCTGATCCTGGCTCTGCTAGAAGCACCTGGCTTGGCATCTTGTCCTCATCTCCTTCTTCTCCTACT CCCAAAGTCACAATGAGCTCCACATTTTCAACTCAGAGAGTCACCACAAGCATGATAATGGACACAGTTGAAACTAGTCGGTGGAACATG CCCAACTTACCTTCCACGACTTCCTTGACACCAAGTAATATTCCAACAAGTGGTGCCATAGGAAAAAGCACCCTGGTTCCCTTGGACACT CCATCTCCAGCCACATCATTGGAGGCATCAGAAGGGGGACTTCCAACCCTCAGCACCTACCCTGAATCAACAAACACACCCAGCATCCAC CTCGGAGCACACGCTAGTTCAGAAAGTCCAAGCACCATCAAACTTACCATGGCTTCAGTAGTAAAACCTGGCTCTTACACACCTCTCACC TTCCCCTCAATAGAGACCCACATTCATGTATCAACAGCCAGAATGGCTTACTCTTCTGGGTCTTCACCTGAGATGACAGCTCCTGGAGAG ACTAACACTGGTAGTACCTGGGACCCCACCACCTACATCACCACTACGGATCCTAAGGATACAAGTTCAGCTCAGGTCTCTACACCCCAC TCAGTGAGGACACTCAGAACCACAGAAAACCATCCAAAGACAGAGTCCGCCACCCCAGCTGCTTACTCTGGAAGTCCTAAAATCTCAAGT TCACCCAATCTCACCAGTCCGGCCACAAAAGCATGGACCATCACAGACACAACTGAACACTCCACTCAATTACATTACACAAAATTGGCA GAAAAATCATCTGGATTTGAGACACAGTCAGCTCCAGGACCTGTCTCTGTAGTAATCCCTACCTCCCCTACCATTGGAAGCAGCACATTG GAACTAACTTCTGATGTCCCAGGGGAACCCCTGGTCCTTGCTCCCAGTGAGCAGACCACAATCACTCTCCCCATGGCAACATGGCTGAGT ACCAGTTTGACAGAGGAAATGGCTTCAACAGACCTTGATATTTCAAGTCCAAGTTCACCCATGAGTACATTTGCTATTTTTCCACCTATG TCCACACCTTCTCATGAACTTTCAAAGTCAGAGGCAGATACCAGTGCCATTAGAAATACAGATTCAACAACGTTGGATCAGCACCTAGGA ATCAGGAGTTTGGGCAGAACTGGGGACTTAACAACTGTTCCTATCACCCCACTGACAACCACGTGGACCAGTGTGATTGAACACTCAACA CAAGCACAGGACACCCTTTCTGCAACGATGAGTCCTACTCACGTGACACAGTCACTCAAAGATCAAACATCTATACCAGCCTCAGCATCC CCTTCCCATCTTACTGAAGTCTACCCTGAGCTCGGGACACAAGGGAGAAGCTCCTCTGAGGCAACCACTTTTTGGAAACCATCTACAGAC ACACTGTCCAGAGAGATTGAGACTGGCCCAACAAACATTCAATCCACTCCACCCATGGACAACACAACAACAGGGAGCAGTAGTAGTGGA GTCACCCTGGGCATAGCCCACCTTCCCATAGGAACATCCTCCCCAGCTGAGACATCCACAAACATGGCACTGGAAAGAAGAAGTTCTACA GCCACTGTCTCTATGGCTGGGACAATGGGACTCCTTGTTACTAGTGCTCCAGGAAGAAGCATCAGCCAGTCATTAGGAAGAGTTTCCTCT GTCCTTTCTGAGTCAACTACTGAAGGAGTCACAGATTCTAGTAAGGGAAGCAGCCCAAGGCTGAACACACAGGGAAATACAGCTCTCTCC TCCTCTCTTGAACCCAGCTATGCTGAAGGAAGCCAGATGAGCACAAGCATCCCTCTAACCTCATCTCCTACAACTCCTGATGTGGAATTC ATAGGGGGCAGCACATTTTGGACCAAGGAGGTCACCACAGTTATGACCTCAGACATCTCCAAGTCTTCAGCAAGGACAGAGTCCAGCTCA GCTACCCTTATGTCCACAGCTTTGGGAAGCACTGAAAATACAGGAAAAGAAAAACTCAGAACTGCCTCTATGGATCTTCCATCTCCAACT CCATCAATGGAGGTGACACCATGGATTTCTCTCACTCTCAGTAATGCCCCCAATACCACAGATTCACTTGACCTCAGCCATGGGGTGCAC ACCAGCTCTGCAGGGACTTTGGCCACTGACAGGTCATTGAATACTGGTGTCACTAGAGCCTCCAGATTGGAAAACGGCTCTGATACCTCT TCTAAGTCCCTGTCTATGGGAAACAGCACTCACACTTCCATGACTTACACAGAGAAGAGTGAAGTGTCTTCTTCAATCCATCCCCGACCT GAGACCTCAGCTCCTGGAGCAGAGACCACTTTGACTTCCACTCCTGGAAACAGGGCCATAAGCTTAACATTGCCTTTTTCATCCATTCCA GTGGAAGAAGTCATTTCTACAGGCATAACCTCAGGACCAGACATCAACTCAGCACCCATGACACATTCTCCCATCACCCCACCAACAATT GTATGGACCAGTACAGGCACAATTGAACAGTCCACTCAACCACTACATGCAGTTTCTTCAGAAAAAGTTTCTGTGCAGACACAGTCAACT CCATATGTCAACTCTGTGGCAGTGTCTGCTTCCCCTACCCATGAGAATTCAGTCTCTTCTGGAAGCAGCACATCCTCTCCATATTCCTCA GCCTCACTTGAATCCTTGGATTCCACAATCAGTAGGAGGAATGCAATCACTTCCTGGCTATGGGACCTCACTACATCTCTCCCCACTACA ACTTGGCCAAGTACTAGTTTATCTGAGGCACTGTCCTCAGGCCATTCTGGGGTTTCAAACCCAAGTTCAACTACGACTGAATTTCCACTC TTTTCAGCTGCATCCACATCTGCTGCTAAGCAAAGAAATCCAGAAACAGAGACCCATGGTCCCCAGAATACAGCCGCGAGTACTTTGAAC ACTGATGCATCCTCGGTCACAGGTCTTTCTGAGACTCCTGTGGGGGCAAGTATCAGCTCTGAAGTCCCTCTTCCAATGGCCATAACTTCT AGATCAGATGTTTCTGGCCTTACATCTGAGAGTACTGCTAACCCGAGTTTAGGCACAGCCTCTTCAGCAGGGACCAAATTAACTAGGACA ATATCCCTGCCCACTTCAGAGTCTTTGGTTTCCTTTAGAATGAACAAGGATCCATGGACAGTGTCAATCCCTTTGGGGTCCCATCCAACT ACTAATACAGAAACAAGCATCCCAGTAAACAGCGCAGGTCCACCTGGCTTGTCCACAGTAGCATCAGATGTAATTGACACACCTTCAGAT GGGGCTGAGAGTATTCCCACTGTCTCCTTTTCCCCCTCCCCTGATACTGAAGTGACAACTATCTCACATTTCCCAGAAAAGACAACTCAT TCATTTAGAACCATTTCATCTCTCACTCATGAGTTGACTTCAAGAGTGACACCTATTCCTGGGGATTGGATGAGTTCAGCTATGTCTACA AAGCCCACAGGAGCCAGTCCCTCCATTACACTGGGAGAGAGAAGGACAATCACCTCTGCTGCTCCAACCACTTCCCCCATAGTTCTCACT GCTAGTTTCACAGAGACCAGCACAGTTTCACTGGATAATGAAACTACAGTAAAAACCTCAGATATCCTTGACGCACGGAAAACAAATGAG CTCCCCTCAGATAGCAGTTCTTCTTCTGATCTGATCAACACCTCCATAGCTTCTTCAACTATGGATGTCACTAAAACAGCCTCCATCAGT CCCACTAGCATCTCAGGAATGACAGCAAGTTCCTCCCCATCTCTCTTCTCTTCAGATAGACCCCAGGTTCCCACATCTACAACAGAGACA AATACAGCCACCTCTCCATCTGTTTCCAGTAACACCTATTCTCTTGATGGGGGCTCCAATGTGGGTGGCACTCCATCCACTTTACCACCC TTTACAATCACCCACCCTGTCGAGACAAGCTCGGCCCTATTAGCCTGGTCTAGACCAGTAAGAACTTTCAGCACCATGGTCAGCACTGAC ACTGCCTCCGGAGAAAATCCTACCTCTAGCAATTCTGTGGTGACTTCTGTTCCAGCACCAGGTACATGGACCAGTGTAGGCAGTACTACT GACTTACCTGCCATGGGCTTTCTCAAGACAAGTCCTGCAGGAGAGGCACACTCACTTCTAGCATCAACTATTGAACCAGCCACTGCCTTC ACTCCCCATCTCTCAGCAGCAGTGGTCACTGGATCCAGTGCTACATCAGAAGCCAGTCTTCTCACTACGAGTGAAAGCAAAGCCATTCAT TCTTCACCACAGACCCCAACTACACCCACCTCTGGAGCAAACTGGGAAACTTCAGCTACTCCTGAGAGCCTTTTGGTAGTCACTGAGACT TCAGACACAACACTTACCTCAAAGATTTTGGTCACAGATACCATCTTGTTTTCAACTGTGTCCACGCCACCTTCTAAATTTCCAAGTACG GGGACTCTGTCTGGAGCTTCCTTCCCTACTTTACTCCCGGACACTCCAGCCATCCCTCTCACTGCCACTGAGCCAACAAGTTCATTAGCT ACATCCTTTGATTCCACCCCACTGGTGACTATAGCTTCGGATAGTCTTGGCACAGTCCCAGAGACTACCCTGACCATGTCAGAGACCTCA AATGGTGATGCACTGGTTCTTAAGACAGTAAGTAACCCAGATAGGAGCATCCCTGGAATCACTATCCAAGGAGTAACAGAAAGTCCACTC CATCCTTCTTCCACTTCCCCCTCTAAGATTGTTGCTCCACGGAATACAACCTATGAAGGTTCGATCACAGTGGCACTTTCTACTTTGCCT GCGGGAACTACTGGTTCCCTTGTATTCAGTCAGAGTTCTGAAAACTCAGAGACAACGGCTTTGGTAGACTCATCAGCTGGGCTTGAGAGG GCATCTGTGATGCCACTAACCACAGGAAGCCAGGGTATGGCTAGCTCTGGAGGAATCAGAAGTGGGTCCACTCACTCAACTGGAACCAAA ACATTTTCTTCTCTCCCTCTGACCATGAACCCAGGTGAGGTTACAGCCATGTCTGAAATCACCACGAACAGACTGACAGCTACTCAATCA ACAGCACCCAAAGGGATACCTGTGAAGCCCACCAGTGCTGAGTCAGGCCTCCTAACACCTGTCTCTGCCTCCTCAAGCCCATCAAAGGCC TTTGCCTCACTGACTACAGCTCCCCCAACTTGGGGGATCCCACAGTCTACCTTGACATTTGAGTTTTCTGAGGTCCCAAGTTTGGATACT AAGTCCGCTTCTTTACCAACTCCTGGACAGTCCCTGAACACCATTCCAGACTCAGATGCAAGCACAGCATCTTCCTCACTGTCCAAGTCT CCAGAAAAAAACCCAAGGGCAAGGATGATGACTTCCACAAAGGCCATAAGTGCAAGCTCATTTCAATCAACAGGTTTTACTGAAACCCCT GAGGGATCTGCCTCCCCTTCTATGGCAGGGCATGAACCCAGAGTCCCCACTTCAGGAACAGGGGACCCTAGATATGCCTCAGAGAGCATG TCTTATCCAGACCCAAGCAAGGCATCATCAGCTATGACATCGACCTCTCTTGCATCAAAACTCACAACTCTCTTCAGCACAGGTCAAGCA GCAAGGTCTGGTTCTAGTTCCTCTCCCATAAGCCTATCCACTGAGAAAGAAACAAGCTTCCTTTCCCCCACTGCATCCACCTCCAGAAAG ACTTCACTATTTCTTGGGCCTTCCATGGCAAGGCAGCCCAACATATTGGTGCATCTTCAGACTTCAGCTCTGACACTTTCTCCAACATCC ACTCTAAATATGTCCCAGGAGGAGCCTCCTGAGTTAACCTCAAGCCAGACCATTGCAGAAGAAGAGGGAACAACAGCTGAAACACAGACG TTAACCTTCACACCATCTGAGACCCCAACATCCTTGTTACCTGTCTCTTCTCCCACAGAACCCACAGCCAGAAGAAAGAGTTCTCCAGAA ACATGGGCAAGCTCTATTTCAGTTCCTGCCAAGACCTCCTTGGTTGAAACAACTGATGGAACGCTAGTGACCACCATAAAGATGTCAAGC CAGGCAGCACAAGGAAATTCCACGTGGCCTGCCCCAGCAGAGGAGACGGGGAGCAGTCCAGCAGAATATTTAAAAGATGCTTCAAAGAAG ATGAAAAATGGGCTAATGTTTGTAAAACTGGTTAACCCCTGTTCAGGAGAAGGAGCCATTTACTTGTTCAATATGTGTCTACAGCAGCTG TTTGAAGTAAAAGTTTTCAAGGAAAAACACCATTCTTGGTTTATAAATCAATCAGTTCAATCAGGAGGTCTTCTCCATTTTGCCACACCT GTGGATCCTCTATTTCTGCTTCTCCACTACCTCATAAAGGCTGATAAGGAGGGGAAGTTTCAGCCCCTTGATCAAGTTGTGGTGGATAAC GTGTTTCCAAATTGCATCTTGTTGCTGAAACTTCCTGGACTTGAGAAGTTACTTCATCATGTGACAGAGGAAAAAGGTAATCCAGAAATA GACAACAAGAAATATTACAAGTACAGCAAAGAGAAGACATTAAAGTGGCTGGAAAAAAAGGTTAATCAAACTGTGGCAGCATTAAAAACC AATAATGTGAATGTCAGTTCCCGGGTACAGTCAACTGCATTTTTCTCTGGTGACCAAGCTTCCACTGACAAGGAAGAGGATTATATTCGT TATGCCCATGGTCTGATATCTGACTACATCCCTAAAGAATTAAGTGATGACTTATCTAAATACTTAAAGCTTCCAGAACCTTCAGCCTCA TTGCCAAATCCTCCATCAAAGAAAATAAAGTTATCAGATGAGCCTGTAGAAGCAAAAGAAGATTACACTAAGTTTAATACTAAAGATTTG AAGACTGAAAAGAAAAATAGCAAAATGACTGCAGCTCAGAAGGCTTTGGCTAAAGTTGACAAGAGTGGAATGAAAAGTATTGATACCTTT TTTGGGGTAAAAAATAAAAAAAAAATTGGAAAGGTTTGAAACTTTGAAAATAAAATCTAGCAAAAATATTTGCTTTTTACATGTTTCAGT TTGTCCTTCCTGACTGTTAATGACTACCTTTGGTTGGGGGAAGGAAGAGGCCAATTTCATGTTCTCTTAAACATTTCTTTGCATTTGGTT TTTGTGTTCCTGAACAAAATATGGGAAAGTGTCTAACTTCATGGCTATGGCCTTTTGGAGTCTCATCTGACATAATGAAAAGTAATCACT TGAAGAGAATTAACATATAGCATCATGATTTTCTCAATAAACTGATGTGTGACAATGTTA >55996_55996_1_MUC16-RNASEH2B_MUC16_chr19_9080450_ENST00000397910_RNASEH2B_chr13_51501542_ENST00000336617_length(amino acids)=3519AA_BP=3223 MRNFGVSGSSEALQRPPSLRGFFLDLHPEANVDLSMLKPSGLPGSSSPTRSLMTGSRSTKATPEMDSGLTGATLSPKTSTGAIVVTEHTL PFTSPDKTLASPTSSVVGRTTQSLGVMSSALPESTSRGMTHSEQRTSPSLSPQVNGTPSRNYPATSMVSGLSSPRTRTSSTEGNFTKEAS TYTLTVETTSGPVTEKYTVPTETSTTEGDSTETPWDTRYIPVKITSPMKTFADSTASKENAPVSMTPAETTVTDSHTPGRTNPSFGTLYS SFLDLSPKGTPNSRGETSLELILSTTGYPFSSPEPGSAGHSRISTSAPLSSSASVLDNKISETSIFSGQSLTSPLSPGVPEARASTMPNS AIPFSMTLSNAETSAERVRSTISSLGTPSISTKQTAETILTFHAFAETMDIPSTHIAKTLASEWLGSPGTLGGTSTSALTTTSPSTTLVS EETNTHHSTSGKETEGTLNTSMTPLETSAPGEESEMTATLVPTLGFTTLDSKIRSPSQVSSSHPTRELRTTGSTSGRQSSSTAAHGSSDI LRATTSSTSKASSWTSESTAQQFSEPQHTQWVETSPSMKTERPPASTSVAAPITTSVPSVVSGFTTLKTSSTKGIWLEETSADTLIGEST AGPTTHQFAVPTGISMTGGSSTRGSQGTTHLLTRATASSETSADLTLATNGVPVSVSPAVSKTAAGSSPPGGTKPSYTMVSSVIPETSSL QSSAFREGTSLGLTPLNTRHPFSSPEPDSAGHTKISTSIPLLSSASVLEDKVSATSTFSHHKATSSITTGTPEISTKTKPSSAVLSSMTL SNAATSPERVRNATSPLTHPSPSGEETAGSVLTLSTSAETTDSPNIHPTGTLTSESSESPSTLSLPSVSGVKTTFSSSTPSTHLFTSGEE TEETSNPSVSQPETSVSRVRTTLASTSVPTPVFPTMDTWPTRSAQFSSSHLVSELRATSSTSVTNSTGSALPKISHLTGTATMSQTNRDT FNDSAAPQSTTWPETSPRFKTGLPSATTTVSTSATSLSATVMVSKFTSPATSSMEATSIREPSTTILTTETTNGPGSMAVASTNIPIGKG YITEGRLDTSHLPIGTTASSETSMDFTMAKESVSMSVSPSQSMDAAGSSTPGRTSQFVDTFSDDVYHLTSREITIPRDGTSSALTPQMTA THPPSPDPGSARSTWLGILSSSPSSPTPKVTMSSTFSTQRVTTSMIMDTVETSRWNMPNLPSTTSLTPSNIPTSGAIGKSTLVPLDTPSP ATSLEASEGGLPTLSTYPESTNTPSIHLGAHASSESPSTIKLTMASVVKPGSYTPLTFPSIETHIHVSTARMAYSSGSSPEMTAPGETNT GSTWDPTTYITTTDPKDTSSAQVSTPHSVRTLRTTENHPKTESATPAAYSGSPKISSSPNLTSPATKAWTITDTTEHSTQLHYTKLAEKS SGFETQSAPGPVSVVIPTSPTIGSSTLELTSDVPGEPLVLAPSEQTTITLPMATWLSTSLTEEMASTDLDISSPSSPMSTFAIFPPMSTP SHELSKSEADTSAIRNTDSTTLDQHLGIRSLGRTGDLTTVPITPLTTTWTSVIEHSTQAQDTLSATMSPTHVTQSLKDQTSIPASASPSH LTEVYPELGTQGRSSSEATTFWKPSTDTLSREIETGPTNIQSTPPMDNTTTGSSSSGVTLGIAHLPIGTSSPAETSTNMALERRSSTATV SMAGTMGLLVTSAPGRSISQSLGRVSSVLSESTTEGVTDSSKGSSPRLNTQGNTALSSSLEPSYAEGSQMSTSIPLTSSPTTPDVEFIGG STFWTKEVTTVMTSDISKSSARTESSSATLMSTALGSTENTGKEKLRTASMDLPSPTPSMEVTPWISLTLSNAPNTTDSLDLSHGVHTSS AGTLATDRSLNTGVTRASRLENGSDTSSKSLSMGNSTHTSMTYTEKSEVSSSIHPRPETSAPGAETTLTSTPGNRAISLTLPFSSIPVEE VISTGITSGPDINSAPMTHSPITPPTIVWTSTGTIEQSTQPLHAVSSEKVSVQTQSTPYVNSVAVSASPTHENSVSSGSSTSSPYSSASL ESLDSTISRRNAITSWLWDLTTSLPTTTWPSTSLSEALSSGHSGVSNPSSTTTEFPLFSAASTSAAKQRNPETETHGPQNTAASTLNTDA SSVTGLSETPVGASISSEVPLPMAITSRSDVSGLTSESTANPSLGTASSAGTKLTRTISLPTSESLVSFRMNKDPWTVSIPLGSHPTTNT ETSIPVNSAGPPGLSTVASDVIDTPSDGAESIPTVSFSPSPDTEVTTISHFPEKTTHSFRTISSLTHELTSRVTPIPGDWMSSAMSTKPT GASPSITLGERRTITSAAPTTSPIVLTASFTETSTVSLDNETTVKTSDILDARKTNELPSDSSSSSDLINTSIASSTMDVTKTASISPTS ISGMTASSSPSLFSSDRPQVPTSTTETNTATSPSVSSNTYSLDGGSNVGGTPSTLPPFTITHPVETSSALLAWSRPVRTFSTMVSTDTAS GENPTSSNSVVTSVPAPGTWTSVGSTTDLPAMGFLKTSPAGEAHSLLASTIEPATAFTPHLSAAVVTGSSATSEASLLTTSESKAIHSSP QTPTTPTSGANWETSATPESLLVVTETSDTTLTSKILVTDTILFSTVSTPPSKFPSTGTLSGASFPTLLPDTPAIPLTATEPTSSLATSF DSTPLVTIASDSLGTVPETTLTMSETSNGDALVLKTVSNPDRSIPGITIQGVTESPLHPSSTSPSKIVAPRNTTYEGSITVALSTLPAGT TGSLVFSQSSENSETTALVDSSAGLERASVMPLTTGSQGMASSGGIRSGSTHSTGTKTFSSLPLTMNPGEVTAMSEITTNRLTATQSTAP KGIPVKPTSAESGLLTPVSASSSPSKAFASLTTAPPTWGIPQSTLTFEFSEVPSLDTKSASLPTPGQSLNTIPDSDASTASSSLSKSPEK NPRARMMTSTKAISASSFQSTGFTETPEGSASPSMAGHEPRVPTSGTGDPRYASESMSYPDPSKASSAMTSTSLASKLTTLFSTGQAARS GSSSSPISLSTEKETSFLSPTASTSRKTSLFLGPSMARQPNILVHLQTSALTLSPTSTLNMSQEEPPELTSSQTIAEEEGTTAETQTLTF TPSETPTSLLPVSSPTEPTARRKSSPETWASSISVPAKTSLVETTDGTLVTTIKMSSQAAQGNSTWPAPAEETGSSPAEYLKDASKKMKN GLMFVKLVNPCSGEGAIYLFNMCLQQLFEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDNVFP NCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKTNNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAH GLISDYIPKELSDDLSKYLKLPEPSASLPNPPSKKIKLSDEPVEAKEDYTKFNTKDLKTEKKNSKMTAAQKALAKVDKSGMKSIDTFFGV KNKKKIGKV -------------------------------------------------------------- >55996_55996_2_MUC16-RNASEH2B_MUC16_chr19_9080450_ENST00000397910_RNASEH2B_chr13_51501542_ENST00000422660_length(transcript)=10986nt_BP=9784nt AAGCGTTGCACAATTCCCCCAACCTCCATACATACGGCAGCTCTTCTAGACACAGGTTTTCCCAGGTCAAATGCGGGGACCCCAGCCATA TCTCCCACCCTGAGAAATTTTGGAGTTTCAGGGAGCTCAGAAGCTCTGCAGAGGCCACCCTCTCTGAGGGGATTCTTCTTAGACCTCCAT CCAGAGGCAAATGTTGACCTGTCCATGCTGAAACCCTCAGGCCTTCCTGGGTCATCTTCTCCCACCCGCTCCTTGATGACAGGGAGCAGG AGCACTAAAGCCACACCAGAAATGGATTCAGGACTGACAGGAGCCACCTTGTCACCTAAGACATCTACAGGTGCAATCGTGGTGACAGAA CATACTCTGCCCTTTACTTCCCCAGATAAGACCTTGGCCAGTCCTACATCTTCGGTTGTGGGAAGAACCACCCAGTCTTTGGGGGTGATG TCCTCTGCTCTCCCTGAGTCAACCTCTAGAGGAATGACACACTCCGAGCAAAGAACCAGCCCATCGCTGAGTCCCCAGGTCAATGGAACT CCCTCTAGGAACTACCCTGCTACAAGCATGGTTTCAGGATTGAGTTCCCCAAGGACCAGGACCAGTTCCACAGAAGGAAATTTTACCAAA GAAGCATCTACATACACACTCACTGTAGAGACCACAAGTGGCCCAGTCACTGAGAAGTACACAGTCCCCACTGAGACCTCAACAACTGAA GGTGACAGCACAGAGACCCCCTGGGACACAAGATATATTCCTGTAAAAATCACATCTCCAATGAAAACATTTGCAGATTCAACTGCATCC AAGGAAAATGCCCCAGTGTCTATGACTCCAGCTGAGACCACAGTTACTGACTCACATACTCCAGGAAGGACAAACCCATCATTTGGGACA CTTTATTCTTCCTTCCTTGACCTATCACCTAAAGGGACCCCAAATTCCAGAGGTGAAACAAGCCTGGAACTGATTCTATCAACCACTGGA TATCCCTTCTCCTCTCCTGAACCTGGCTCTGCAGGACACAGCAGAATAAGTACCAGTGCGCCTTTGTCATCATCTGCTTCAGTTCTCGAT AATAAAATATCAGAGACCAGCATATTCTCAGGCCAGAGTCTCACCTCCCCTCTGTCTCCTGGGGTGCCCGAGGCCAGAGCCAGCACAATG CCCAACTCAGCTATCCCTTTTTCCATGACACTAAGCAATGCAGAAACAAGTGCCGAAAGGGTCAGAAGCACAATTTCCTCTCTGGGGACT CCATCAATATCCACAAAGCAGACAGCAGAGACTATCCTTACCTTCCATGCCTTCGCTGAGACCATGGATATACCCAGCACCCACATAGCC AAGACTTTGGCTTCAGAATGGTTGGGAAGTCCAGGTACCCTTGGTGGCACCAGCACTTCAGCGCTGACAACCACATCTCCATCTACCACT TTAGTCTCAGAGGAGACCAACACCCATCACTCCACGAGTGGAAAGGAAACAGAAGGAACTTTGAATACATCTATGACTCCACTTGAGACC TCTGCTCCTGGAGAAGAGTCCGAAATGACTGCCACCTTGGTCCCCACTCTAGGTTTTACAACTCTTGACAGCAAGATCAGAAGTCCATCT CAGGTCTCTTCATCCCACCCAACAAGAGAGCTCAGAACCACAGGCAGCACCTCTGGGAGGCAGAGTTCCAGCACAGCTGCCCACGGGAGC TCTGACATCCTGAGGGCAACCACTTCCAGCACCTCAAAAGCATCATCATGGACCAGTGAAAGCACAGCTCAGCAATTTAGTGAACCCCAG CACACACAGTGGGTGGAGACAAGTCCTAGCATGAAAACAGAGAGACCCCCAGCATCAACCAGTGTGGCAGCCCCTATCACCACTTCTGTT CCCTCAGTGGTCTCTGGCTTCACCACCCTGAAGACCAGCTCCACAAAAGGGATTTGGCTTGAAGAAACATCTGCAGACACACTCATCGGA GAATCCACAGCTGGCCCAACCACCCATCAGTTTGCTGTTCCCACTGGGATTTCAATGACAGGAGGCAGCAGCACCAGGGGAAGCCAGGGC ACAACCCACCTACTCACCAGAGCCACAGCATCATCTGAGACATCCGCAGATTTGACTCTGGCCACGAACGGTGTCCCAGTCTCCGTGTCT CCAGCAGTGAGCAAGACGGCTGCTGGCTCAAGTCCTCCAGGAGGGACAAAGCCATCATATACAATGGTTTCTTCTGTCATCCCTGAGACA TCATCTCTACAGTCCTCAGCTTTCAGGGAAGGAACCAGCCTGGGACTGACTCCATTAAACACTAGACATCCCTTCTCTTCCCCTGAACCA GACTCTGCAGGACACACCAAGATAAGCACCAGCATTCCTCTGTTGTCATCTGCTTCAGTTCTTGAGGATAAAGTGTCAGCGACCAGCACA TTCTCACACCACAAAGCCACCTCATCTATTACCACAGGGACTCCTGAAATCTCAACAAAGACAAAGCCCAGCTCAGCCGTTCTTTCCTCC ATGACCCTAAGCAATGCAGCAACAAGTCCTGAAAGAGTCAGAAATGCAACTTCCCCTCTGACTCATCCATCTCCATCAGGGGAAGAGACA GCAGGGAGTGTCCTCACTCTCAGCACCTCTGCTGAGACTACAGACTCACCTAACATCCACCCAACTGGGACACTGACTTCAGAATCGTCA GAGAGTCCTAGCACTCTCAGCCTCCCAAGTGTCTCTGGAGTCAAAACCACATTTTCTTCATCTACTCCTTCCACTCATCTATTTACTAGT GGAGAAGAAACAGAGGAAACTTCGAATCCATCTGTGTCTCAACCTGAGACTTCTGTTTCCAGAGTAAGGACCACCTTGGCCAGCACCTCT GTCCCTACCCCAGTATTCCCCACCATGGACACCTGGCCTACACGTTCAGCTCAGTTCTCTTCATCCCACCTAGTGAGTGAGCTCAGAGCT ACGAGCAGTACCTCAGTTACAAACTCAACTGGTTCAGCTCTTCCTAAAATATCTCACCTCACTGGGACGGCAACAATGTCACAGACCAAT AGAGACACGTTTAATGACTCTGCTGCACCCCAAAGCACAACTTGGCCAGAGACTAGTCCCAGATTCAAGACAGGGTTACCTTCAGCAACA ACCACTGTTTCAACCTCTGCCACTTCTCTCTCTGCTACTGTAATGGTCTCTAAATTCACTTCTCCAGCAACTAGTTCCATGGAAGCAACT TCTATCAGGGAACCATCAACAACCATCCTCACAACAGAGACCACGAATGGCCCAGGCTCTATGGCTGTGGCTTCTACCAACATCCCAATT GGAAAGGGCTACATTACTGAAGGAAGATTGGACACAAGCCATCTGCCCATTGGAACCACAGCTTCCTCTGAGACATCTATGGATTTTACC ATGGCCAAAGAAAGTGTCTCAATGTCAGTATCTCCATCTCAGTCCATGGATGCTGCTGGCTCAAGCACTCCAGGAAGGACAAGCCAATTC GTTGACACATTTTCTGATGATGTCTATCATTTAACATCCAGAGAAATTACAATACCTAGAGATGGAACAAGCTCAGCTCTGACTCCACAA ATGACTGCAACTCACCCTCCATCTCCTGATCCTGGCTCTGCTAGAAGCACCTGGCTTGGCATCTTGTCCTCATCTCCTTCTTCTCCTACT CCCAAAGTCACAATGAGCTCCACATTTTCAACTCAGAGAGTCACCACAAGCATGATAATGGACACAGTTGAAACTAGTCGGTGGAACATG CCCAACTTACCTTCCACGACTTCCTTGACACCAAGTAATATTCCAACAAGTGGTGCCATAGGAAAAAGCACCCTGGTTCCCTTGGACACT CCATCTCCAGCCACATCATTGGAGGCATCAGAAGGGGGACTTCCAACCCTCAGCACCTACCCTGAATCAACAAACACACCCAGCATCCAC CTCGGAGCACACGCTAGTTCAGAAAGTCCAAGCACCATCAAACTTACCATGGCTTCAGTAGTAAAACCTGGCTCTTACACACCTCTCACC TTCCCCTCAATAGAGACCCACATTCATGTATCAACAGCCAGAATGGCTTACTCTTCTGGGTCTTCACCTGAGATGACAGCTCCTGGAGAG ACTAACACTGGTAGTACCTGGGACCCCACCACCTACATCACCACTACGGATCCTAAGGATACAAGTTCAGCTCAGGTCTCTACACCCCAC TCAGTGAGGACACTCAGAACCACAGAAAACCATCCAAAGACAGAGTCCGCCACCCCAGCTGCTTACTCTGGAAGTCCTAAAATCTCAAGT TCACCCAATCTCACCAGTCCGGCCACAAAAGCATGGACCATCACAGACACAACTGAACACTCCACTCAATTACATTACACAAAATTGGCA GAAAAATCATCTGGATTTGAGACACAGTCAGCTCCAGGACCTGTCTCTGTAGTAATCCCTACCTCCCCTACCATTGGAAGCAGCACATTG GAACTAACTTCTGATGTCCCAGGGGAACCCCTGGTCCTTGCTCCCAGTGAGCAGACCACAATCACTCTCCCCATGGCAACATGGCTGAGT ACCAGTTTGACAGAGGAAATGGCTTCAACAGACCTTGATATTTCAAGTCCAAGTTCACCCATGAGTACATTTGCTATTTTTCCACCTATG TCCACACCTTCTCATGAACTTTCAAAGTCAGAGGCAGATACCAGTGCCATTAGAAATACAGATTCAACAACGTTGGATCAGCACCTAGGA ATCAGGAGTTTGGGCAGAACTGGGGACTTAACAACTGTTCCTATCACCCCACTGACAACCACGTGGACCAGTGTGATTGAACACTCAACA CAAGCACAGGACACCCTTTCTGCAACGATGAGTCCTACTCACGTGACACAGTCACTCAAAGATCAAACATCTATACCAGCCTCAGCATCC CCTTCCCATCTTACTGAAGTCTACCCTGAGCTCGGGACACAAGGGAGAAGCTCCTCTGAGGCAACCACTTTTTGGAAACCATCTACAGAC ACACTGTCCAGAGAGATTGAGACTGGCCCAACAAACATTCAATCCACTCCACCCATGGACAACACAACAACAGGGAGCAGTAGTAGTGGA GTCACCCTGGGCATAGCCCACCTTCCCATAGGAACATCCTCCCCAGCTGAGACATCCACAAACATGGCACTGGAAAGAAGAAGTTCTACA GCCACTGTCTCTATGGCTGGGACAATGGGACTCCTTGTTACTAGTGCTCCAGGAAGAAGCATCAGCCAGTCATTAGGAAGAGTTTCCTCT GTCCTTTCTGAGTCAACTACTGAAGGAGTCACAGATTCTAGTAAGGGAAGCAGCCCAAGGCTGAACACACAGGGAAATACAGCTCTCTCC TCCTCTCTTGAACCCAGCTATGCTGAAGGAAGCCAGATGAGCACAAGCATCCCTCTAACCTCATCTCCTACAACTCCTGATGTGGAATTC ATAGGGGGCAGCACATTTTGGACCAAGGAGGTCACCACAGTTATGACCTCAGACATCTCCAAGTCTTCAGCAAGGACAGAGTCCAGCTCA GCTACCCTTATGTCCACAGCTTTGGGAAGCACTGAAAATACAGGAAAAGAAAAACTCAGAACTGCCTCTATGGATCTTCCATCTCCAACT CCATCAATGGAGGTGACACCATGGATTTCTCTCACTCTCAGTAATGCCCCCAATACCACAGATTCACTTGACCTCAGCCATGGGGTGCAC ACCAGCTCTGCAGGGACTTTGGCCACTGACAGGTCATTGAATACTGGTGTCACTAGAGCCTCCAGATTGGAAAACGGCTCTGATACCTCT TCTAAGTCCCTGTCTATGGGAAACAGCACTCACACTTCCATGACTTACACAGAGAAGAGTGAAGTGTCTTCTTCAATCCATCCCCGACCT GAGACCTCAGCTCCTGGAGCAGAGACCACTTTGACTTCCACTCCTGGAAACAGGGCCATAAGCTTAACATTGCCTTTTTCATCCATTCCA GTGGAAGAAGTCATTTCTACAGGCATAACCTCAGGACCAGACATCAACTCAGCACCCATGACACATTCTCCCATCACCCCACCAACAATT GTATGGACCAGTACAGGCACAATTGAACAGTCCACTCAACCACTACATGCAGTTTCTTCAGAAAAAGTTTCTGTGCAGACACAGTCAACT CCATATGTCAACTCTGTGGCAGTGTCTGCTTCCCCTACCCATGAGAATTCAGTCTCTTCTGGAAGCAGCACATCCTCTCCATATTCCTCA GCCTCACTTGAATCCTTGGATTCCACAATCAGTAGGAGGAATGCAATCACTTCCTGGCTATGGGACCTCACTACATCTCTCCCCACTACA ACTTGGCCAAGTACTAGTTTATCTGAGGCACTGTCCTCAGGCCATTCTGGGGTTTCAAACCCAAGTTCAACTACGACTGAATTTCCACTC TTTTCAGCTGCATCCACATCTGCTGCTAAGCAAAGAAATCCAGAAACAGAGACCCATGGTCCCCAGAATACAGCCGCGAGTACTTTGAAC ACTGATGCATCCTCGGTCACAGGTCTTTCTGAGACTCCTGTGGGGGCAAGTATCAGCTCTGAAGTCCCTCTTCCAATGGCCATAACTTCT AGATCAGATGTTTCTGGCCTTACATCTGAGAGTACTGCTAACCCGAGTTTAGGCACAGCCTCTTCAGCAGGGACCAAATTAACTAGGACA ATATCCCTGCCCACTTCAGAGTCTTTGGTTTCCTTTAGAATGAACAAGGATCCATGGACAGTGTCAATCCCTTTGGGGTCCCATCCAACT ACTAATACAGAAACAAGCATCCCAGTAAACAGCGCAGGTCCACCTGGCTTGTCCACAGTAGCATCAGATGTAATTGACACACCTTCAGAT GGGGCTGAGAGTATTCCCACTGTCTCCTTTTCCCCCTCCCCTGATACTGAAGTGACAACTATCTCACATTTCCCAGAAAAGACAACTCAT TCATTTAGAACCATTTCATCTCTCACTCATGAGTTGACTTCAAGAGTGACACCTATTCCTGGGGATTGGATGAGTTCAGCTATGTCTACA AAGCCCACAGGAGCCAGTCCCTCCATTACACTGGGAGAGAGAAGGACAATCACCTCTGCTGCTCCAACCACTTCCCCCATAGTTCTCACT GCTAGTTTCACAGAGACCAGCACAGTTTCACTGGATAATGAAACTACAGTAAAAACCTCAGATATCCTTGACGCACGGAAAACAAATGAG CTCCCCTCAGATAGCAGTTCTTCTTCTGATCTGATCAACACCTCCATAGCTTCTTCAACTATGGATGTCACTAAAACAGCCTCCATCAGT CCCACTAGCATCTCAGGAATGACAGCAAGTTCCTCCCCATCTCTCTTCTCTTCAGATAGACCCCAGGTTCCCACATCTACAACAGAGACA AATACAGCCACCTCTCCATCTGTTTCCAGTAACACCTATTCTCTTGATGGGGGCTCCAATGTGGGTGGCACTCCATCCACTTTACCACCC TTTACAATCACCCACCCTGTCGAGACAAGCTCGGCCCTATTAGCCTGGTCTAGACCAGTAAGAACTTTCAGCACCATGGTCAGCACTGAC ACTGCCTCCGGAGAAAATCCTACCTCTAGCAATTCTGTGGTGACTTCTGTTCCAGCACCAGGTACATGGACCAGTGTAGGCAGTACTACT GACTTACCTGCCATGGGCTTTCTCAAGACAAGTCCTGCAGGAGAGGCACACTCACTTCTAGCATCAACTATTGAACCAGCCACTGCCTTC ACTCCCCATCTCTCAGCAGCAGTGGTCACTGGATCCAGTGCTACATCAGAAGCCAGTCTTCTCACTACGAGTGAAAGCAAAGCCATTCAT TCTTCACCACAGACCCCAACTACACCCACCTCTGGAGCAAACTGGGAAACTTCAGCTACTCCTGAGAGCCTTTTGGTAGTCACTGAGACT TCAGACACAACACTTACCTCAAAGATTTTGGTCACAGATACCATCTTGTTTTCAACTGTGTCCACGCCACCTTCTAAATTTCCAAGTACG GGGACTCTGTCTGGAGCTTCCTTCCCTACTTTACTCCCGGACACTCCAGCCATCCCTCTCACTGCCACTGAGCCAACAAGTTCATTAGCT ACATCCTTTGATTCCACCCCACTGGTGACTATAGCTTCGGATAGTCTTGGCACAGTCCCAGAGACTACCCTGACCATGTCAGAGACCTCA AATGGTGATGCACTGGTTCTTAAGACAGTAAGTAACCCAGATAGGAGCATCCCTGGAATCACTATCCAAGGAGTAACAGAAAGTCCACTC CATCCTTCTTCCACTTCCCCCTCTAAGATTGTTGCTCCACGGAATACAACCTATGAAGGTTCGATCACAGTGGCACTTTCTACTTTGCCT GCGGGAACTACTGGTTCCCTTGTATTCAGTCAGAGTTCTGAAAACTCAGAGACAACGGCTTTGGTAGACTCATCAGCTGGGCTTGAGAGG GCATCTGTGATGCCACTAACCACAGGAAGCCAGGGTATGGCTAGCTCTGGAGGAATCAGAAGTGGGTCCACTCACTCAACTGGAACCAAA ACATTTTCTTCTCTCCCTCTGACCATGAACCCAGGTGAGGTTACAGCCATGTCTGAAATCACCACGAACAGACTGACAGCTACTCAATCA ACAGCACCCAAAGGGATACCTGTGAAGCCCACCAGTGCTGAGTCAGGCCTCCTAACACCTGTCTCTGCCTCCTCAAGCCCATCAAAGGCC TTTGCCTCACTGACTACAGCTCCCCCAACTTGGGGGATCCCACAGTCTACCTTGACATTTGAGTTTTCTGAGGTCCCAAGTTTGGATACT AAGTCCGCTTCTTTACCAACTCCTGGACAGTCCCTGAACACCATTCCAGACTCAGATGCAAGCACAGCATCTTCCTCACTGTCCAAGTCT CCAGAAAAAAACCCAAGGGCAAGGATGATGACTTCCACAAAGGCCATAAGTGCAAGCTCATTTCAATCAACAGGTTTTACTGAAACCCCT GAGGGATCTGCCTCCCCTTCTATGGCAGGGCATGAACCCAGAGTCCCCACTTCAGGAACAGGGGACCCTAGATATGCCTCAGAGAGCATG TCTTATCCAGACCCAAGCAAGGCATCATCAGCTATGACATCGACCTCTCTTGCATCAAAACTCACAACTCTCTTCAGCACAGGTCAAGCA GCAAGGTCTGGTTCTAGTTCCTCTCCCATAAGCCTATCCACTGAGAAAGAAACAAGCTTCCTTTCCCCCACTGCATCCACCTCCAGAAAG ACTTCACTATTTCTTGGGCCTTCCATGGCAAGGCAGCCCAACATATTGGTGCATCTTCAGACTTCAGCTCTGACACTTTCTCCAACATCC ACTCTAAATATGTCCCAGGAGGAGCCTCCTGAGTTAACCTCAAGCCAGACCATTGCAGAAGAAGAGGGAACAACAGCTGAAACACAGACG TTAACCTTCACACCATCTGAGACCCCAACATCCTTGTTACCTGTCTCTTCTCCCACAGAACCCACAGCCAGAAGAAAGAGTTCTCCAGAA ACATGGGCAAGCTCTATTTCAGTTCCTGCCAAGACCTCCTTGGTTGAAACAACTGATGGAACGCTAGTGACCACCATAAAGATGTCAAGC CAGGCAGCACAAGGAAATTCCACGTGGCCTGCCCCAGCAGAGGAGACGGGGAGCAGTCCAGCAGAATATTTAAAAGATGCTTCAAAGAAG ATGAAAAATGGGCTAATGTTTGTAAAACTGGTTAACCCCTGTTCAGGAGAAGGAGCCATTTACTTGTTCAATATGTGTCTACAGCAGCTG TTTGAAGTAAAAGTTTTCAAGGAAAAACACCATTCTTGGTTTATAAATCAATCAGTTCAATCAGGAGGTCTTCTCCATTTTGCCACACCT GTGGATCCTCTATTTCTGCTTCTCCACTACCTCATAAAGGCTGATAAGGAGGGGAAGTTTCAGCCCCTTGATCAAGTTGTGGTGGATAAC GTGTTTCCAAATTGCATCTTGTTGCTGAAACTTCCTGGACTTGAGAAGTTACTTCATCATGTGACAGAGGAAAAAGGTAATCCAGAAATA GACAACAAGAAATATTACAAGTACAGCAAAGAGAAGACATTAAAGTGGCTGGAAAAAAAGGTTAATCAAACTGTGGCAGCATTAAAAACC AATAATGTGAATGTCAGTTCCCGGGTACAGTCAACTGCATTTTTCTCTGGTGACCAAGCTTCCACTGACAAGGAAGAGGATTATATTCGT TATGCCCATGGTCTGATATCTGACTACATCCCTAAAGAATTAAGTGATGACTTATCTAAATACTTAAAGCTTCCAGAACCTTCAGCCTCA TTGCCAAATCCTCCATCAAAGATGGCAGCACAAAGACAGAAAAGGGGCAAGTGATGGTGGTGGCTCCACGCAAGGCTTGGCGGTTTTCCC TGCAACTTCAGACACTCCCAGAGGACTCGGACTTTTTCTTCTGCACTTTTTTGGAAAATCGCCAGGTGCCAAAAGGTGCATTTTAAAGCG CTGACTGTAAATGCTTTATTTCTTTGATTAGTACCACTAGTCTATGTGGGCAGCGGCATTCCTCCCTGGAGCACTCAGCTAGGCGGTTCC GTCCAGGAGCTTGAAAGCATCCCAGCGGTGCACCTGTTCAGTCTGAGGACCTCAAGCTTGGGTCAGGCCAGCATGTTTTAGGTATGGATG TGGTGACTTAAAGTACTTGATTGTCTTGATTTCACCCTGAAAGCTTTGGCAAACCAAGTTTCAACCCTTACTTTAAAAATCTGACACTGC TTTACTCCATATCAATTTGGAAGCTTCTAATTCATAAATATACCTAAACGTTGGCATTTTATCTCTCCAGGAGTTATTAAACATTTCTTC CTTTTT >55996_55996_2_MUC16-RNASEH2B_MUC16_chr19_9080450_ENST00000397910_RNASEH2B_chr13_51501542_ENST00000422660_length(amino acids)=3464AA_BP=3223 MRNFGVSGSSEALQRPPSLRGFFLDLHPEANVDLSMLKPSGLPGSSSPTRSLMTGSRSTKATPEMDSGLTGATLSPKTSTGAIVVTEHTL PFTSPDKTLASPTSSVVGRTTQSLGVMSSALPESTSRGMTHSEQRTSPSLSPQVNGTPSRNYPATSMVSGLSSPRTRTSSTEGNFTKEAS TYTLTVETTSGPVTEKYTVPTETSTTEGDSTETPWDTRYIPVKITSPMKTFADSTASKENAPVSMTPAETTVTDSHTPGRTNPSFGTLYS SFLDLSPKGTPNSRGETSLELILSTTGYPFSSPEPGSAGHSRISTSAPLSSSASVLDNKISETSIFSGQSLTSPLSPGVPEARASTMPNS AIPFSMTLSNAETSAERVRSTISSLGTPSISTKQTAETILTFHAFAETMDIPSTHIAKTLASEWLGSPGTLGGTSTSALTTTSPSTTLVS EETNTHHSTSGKETEGTLNTSMTPLETSAPGEESEMTATLVPTLGFTTLDSKIRSPSQVSSSHPTRELRTTGSTSGRQSSSTAAHGSSDI LRATTSSTSKASSWTSESTAQQFSEPQHTQWVETSPSMKTERPPASTSVAAPITTSVPSVVSGFTTLKTSSTKGIWLEETSADTLIGEST AGPTTHQFAVPTGISMTGGSSTRGSQGTTHLLTRATASSETSADLTLATNGVPVSVSPAVSKTAAGSSPPGGTKPSYTMVSSVIPETSSL QSSAFREGTSLGLTPLNTRHPFSSPEPDSAGHTKISTSIPLLSSASVLEDKVSATSTFSHHKATSSITTGTPEISTKTKPSSAVLSSMTL SNAATSPERVRNATSPLTHPSPSGEETAGSVLTLSTSAETTDSPNIHPTGTLTSESSESPSTLSLPSVSGVKTTFSSSTPSTHLFTSGEE TEETSNPSVSQPETSVSRVRTTLASTSVPTPVFPTMDTWPTRSAQFSSSHLVSELRATSSTSVTNSTGSALPKISHLTGTATMSQTNRDT FNDSAAPQSTTWPETSPRFKTGLPSATTTVSTSATSLSATVMVSKFTSPATSSMEATSIREPSTTILTTETTNGPGSMAVASTNIPIGKG YITEGRLDTSHLPIGTTASSETSMDFTMAKESVSMSVSPSQSMDAAGSSTPGRTSQFVDTFSDDVYHLTSREITIPRDGTSSALTPQMTA THPPSPDPGSARSTWLGILSSSPSSPTPKVTMSSTFSTQRVTTSMIMDTVETSRWNMPNLPSTTSLTPSNIPTSGAIGKSTLVPLDTPSP ATSLEASEGGLPTLSTYPESTNTPSIHLGAHASSESPSTIKLTMASVVKPGSYTPLTFPSIETHIHVSTARMAYSSGSSPEMTAPGETNT GSTWDPTTYITTTDPKDTSSAQVSTPHSVRTLRTTENHPKTESATPAAYSGSPKISSSPNLTSPATKAWTITDTTEHSTQLHYTKLAEKS SGFETQSAPGPVSVVIPTSPTIGSSTLELTSDVPGEPLVLAPSEQTTITLPMATWLSTSLTEEMASTDLDISSPSSPMSTFAIFPPMSTP SHELSKSEADTSAIRNTDSTTLDQHLGIRSLGRTGDLTTVPITPLTTTWTSVIEHSTQAQDTLSATMSPTHVTQSLKDQTSIPASASPSH LTEVYPELGTQGRSSSEATTFWKPSTDTLSREIETGPTNIQSTPPMDNTTTGSSSSGVTLGIAHLPIGTSSPAETSTNMALERRSSTATV SMAGTMGLLVTSAPGRSISQSLGRVSSVLSESTTEGVTDSSKGSSPRLNTQGNTALSSSLEPSYAEGSQMSTSIPLTSSPTTPDVEFIGG STFWTKEVTTVMTSDISKSSARTESSSATLMSTALGSTENTGKEKLRTASMDLPSPTPSMEVTPWISLTLSNAPNTTDSLDLSHGVHTSS AGTLATDRSLNTGVTRASRLENGSDTSSKSLSMGNSTHTSMTYTEKSEVSSSIHPRPETSAPGAETTLTSTPGNRAISLTLPFSSIPVEE VISTGITSGPDINSAPMTHSPITPPTIVWTSTGTIEQSTQPLHAVSSEKVSVQTQSTPYVNSVAVSASPTHENSVSSGSSTSSPYSSASL ESLDSTISRRNAITSWLWDLTTSLPTTTWPSTSLSEALSSGHSGVSNPSSTTTEFPLFSAASTSAAKQRNPETETHGPQNTAASTLNTDA SSVTGLSETPVGASISSEVPLPMAITSRSDVSGLTSESTANPSLGTASSAGTKLTRTISLPTSESLVSFRMNKDPWTVSIPLGSHPTTNT ETSIPVNSAGPPGLSTVASDVIDTPSDGAESIPTVSFSPSPDTEVTTISHFPEKTTHSFRTISSLTHELTSRVTPIPGDWMSSAMSTKPT GASPSITLGERRTITSAAPTTSPIVLTASFTETSTVSLDNETTVKTSDILDARKTNELPSDSSSSSDLINTSIASSTMDVTKTASISPTS ISGMTASSSPSLFSSDRPQVPTSTTETNTATSPSVSSNTYSLDGGSNVGGTPSTLPPFTITHPVETSSALLAWSRPVRTFSTMVSTDTAS GENPTSSNSVVTSVPAPGTWTSVGSTTDLPAMGFLKTSPAGEAHSLLASTIEPATAFTPHLSAAVVTGSSATSEASLLTTSESKAIHSSP QTPTTPTSGANWETSATPESLLVVTETSDTTLTSKILVTDTILFSTVSTPPSKFPSTGTLSGASFPTLLPDTPAIPLTATEPTSSLATSF DSTPLVTIASDSLGTVPETTLTMSETSNGDALVLKTVSNPDRSIPGITIQGVTESPLHPSSTSPSKIVAPRNTTYEGSITVALSTLPAGT TGSLVFSQSSENSETTALVDSSAGLERASVMPLTTGSQGMASSGGIRSGSTHSTGTKTFSSLPLTMNPGEVTAMSEITTNRLTATQSTAP KGIPVKPTSAESGLLTPVSASSSPSKAFASLTTAPPTWGIPQSTLTFEFSEVPSLDTKSASLPTPGQSLNTIPDSDASTASSSLSKSPEK NPRARMMTSTKAISASSFQSTGFTETPEGSASPSMAGHEPRVPTSGTGDPRYASESMSYPDPSKASSAMTSTSLASKLTTLFSTGQAARS GSSSSPISLSTEKETSFLSPTASTSRKTSLFLGPSMARQPNILVHLQTSALTLSPTSTLNMSQEEPPELTSSQTIAEEEGTTAETQTLTF TPSETPTSLLPVSSPTEPTARRKSSPETWASSISVPAKTSLVETTDGTLVTTIKMSSQAAQGNSTWPAPAEETGSSPAEYLKDASKKMKN GLMFVKLVNPCSGEGAIYLFNMCLQQLFEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDNVFP NCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKTNNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAH GLISDYIPKELSDDLSKYLKLPEPSASLPNPPSKMAAQRQKRGK -------------------------------------------------------------- >55996_55996_3_MUC16-RNASEH2B_MUC16_chr19_9080451_ENST00000397910_RNASEH2B_chr13_51501543_ENST00000336617_length(transcript)=10950nt_BP=9784nt AAGCGTTGCACAATTCCCCCAACCTCCATACATACGGCAGCTCTTCTAGACACAGGTTTTCCCAGGTCAAATGCGGGGACCCCAGCCATA TCTCCCACCCTGAGAAATTTTGGAGTTTCAGGGAGCTCAGAAGCTCTGCAGAGGCCACCCTCTCTGAGGGGATTCTTCTTAGACCTCCAT CCAGAGGCAAATGTTGACCTGTCCATGCTGAAACCCTCAGGCCTTCCTGGGTCATCTTCTCCCACCCGCTCCTTGATGACAGGGAGCAGG AGCACTAAAGCCACACCAGAAATGGATTCAGGACTGACAGGAGCCACCTTGTCACCTAAGACATCTACAGGTGCAATCGTGGTGACAGAA CATACTCTGCCCTTTACTTCCCCAGATAAGACCTTGGCCAGTCCTACATCTTCGGTTGTGGGAAGAACCACCCAGTCTTTGGGGGTGATG TCCTCTGCTCTCCCTGAGTCAACCTCTAGAGGAATGACACACTCCGAGCAAAGAACCAGCCCATCGCTGAGTCCCCAGGTCAATGGAACT CCCTCTAGGAACTACCCTGCTACAAGCATGGTTTCAGGATTGAGTTCCCCAAGGACCAGGACCAGTTCCACAGAAGGAAATTTTACCAAA GAAGCATCTACATACACACTCACTGTAGAGACCACAAGTGGCCCAGTCACTGAGAAGTACACAGTCCCCACTGAGACCTCAACAACTGAA GGTGACAGCACAGAGACCCCCTGGGACACAAGATATATTCCTGTAAAAATCACATCTCCAATGAAAACATTTGCAGATTCAACTGCATCC AAGGAAAATGCCCCAGTGTCTATGACTCCAGCTGAGACCACAGTTACTGACTCACATACTCCAGGAAGGACAAACCCATCATTTGGGACA CTTTATTCTTCCTTCCTTGACCTATCACCTAAAGGGACCCCAAATTCCAGAGGTGAAACAAGCCTGGAACTGATTCTATCAACCACTGGA TATCCCTTCTCCTCTCCTGAACCTGGCTCTGCAGGACACAGCAGAATAAGTACCAGTGCGCCTTTGTCATCATCTGCTTCAGTTCTCGAT AATAAAATATCAGAGACCAGCATATTCTCAGGCCAGAGTCTCACCTCCCCTCTGTCTCCTGGGGTGCCCGAGGCCAGAGCCAGCACAATG CCCAACTCAGCTATCCCTTTTTCCATGACACTAAGCAATGCAGAAACAAGTGCCGAAAGGGTCAGAAGCACAATTTCCTCTCTGGGGACT CCATCAATATCCACAAAGCAGACAGCAGAGACTATCCTTACCTTCCATGCCTTCGCTGAGACCATGGATATACCCAGCACCCACATAGCC AAGACTTTGGCTTCAGAATGGTTGGGAAGTCCAGGTACCCTTGGTGGCACCAGCACTTCAGCGCTGACAACCACATCTCCATCTACCACT TTAGTCTCAGAGGAGACCAACACCCATCACTCCACGAGTGGAAAGGAAACAGAAGGAACTTTGAATACATCTATGACTCCACTTGAGACC TCTGCTCCTGGAGAAGAGTCCGAAATGACTGCCACCTTGGTCCCCACTCTAGGTTTTACAACTCTTGACAGCAAGATCAGAAGTCCATCT CAGGTCTCTTCATCCCACCCAACAAGAGAGCTCAGAACCACAGGCAGCACCTCTGGGAGGCAGAGTTCCAGCACAGCTGCCCACGGGAGC TCTGACATCCTGAGGGCAACCACTTCCAGCACCTCAAAAGCATCATCATGGACCAGTGAAAGCACAGCTCAGCAATTTAGTGAACCCCAG CACACACAGTGGGTGGAGACAAGTCCTAGCATGAAAACAGAGAGACCCCCAGCATCAACCAGTGTGGCAGCCCCTATCACCACTTCTGTT CCCTCAGTGGTCTCTGGCTTCACCACCCTGAAGACCAGCTCCACAAAAGGGATTTGGCTTGAAGAAACATCTGCAGACACACTCATCGGA GAATCCACAGCTGGCCCAACCACCCATCAGTTTGCTGTTCCCACTGGGATTTCAATGACAGGAGGCAGCAGCACCAGGGGAAGCCAGGGC ACAACCCACCTACTCACCAGAGCCACAGCATCATCTGAGACATCCGCAGATTTGACTCTGGCCACGAACGGTGTCCCAGTCTCCGTGTCT CCAGCAGTGAGCAAGACGGCTGCTGGCTCAAGTCCTCCAGGAGGGACAAAGCCATCATATACAATGGTTTCTTCTGTCATCCCTGAGACA TCATCTCTACAGTCCTCAGCTTTCAGGGAAGGAACCAGCCTGGGACTGACTCCATTAAACACTAGACATCCCTTCTCTTCCCCTGAACCA GACTCTGCAGGACACACCAAGATAAGCACCAGCATTCCTCTGTTGTCATCTGCTTCAGTTCTTGAGGATAAAGTGTCAGCGACCAGCACA TTCTCACACCACAAAGCCACCTCATCTATTACCACAGGGACTCCTGAAATCTCAACAAAGACAAAGCCCAGCTCAGCCGTTCTTTCCTCC ATGACCCTAAGCAATGCAGCAACAAGTCCTGAAAGAGTCAGAAATGCAACTTCCCCTCTGACTCATCCATCTCCATCAGGGGAAGAGACA GCAGGGAGTGTCCTCACTCTCAGCACCTCTGCTGAGACTACAGACTCACCTAACATCCACCCAACTGGGACACTGACTTCAGAATCGTCA GAGAGTCCTAGCACTCTCAGCCTCCCAAGTGTCTCTGGAGTCAAAACCACATTTTCTTCATCTACTCCTTCCACTCATCTATTTACTAGT GGAGAAGAAACAGAGGAAACTTCGAATCCATCTGTGTCTCAACCTGAGACTTCTGTTTCCAGAGTAAGGACCACCTTGGCCAGCACCTCT GTCCCTACCCCAGTATTCCCCACCATGGACACCTGGCCTACACGTTCAGCTCAGTTCTCTTCATCCCACCTAGTGAGTGAGCTCAGAGCT ACGAGCAGTACCTCAGTTACAAACTCAACTGGTTCAGCTCTTCCTAAAATATCTCACCTCACTGGGACGGCAACAATGTCACAGACCAAT AGAGACACGTTTAATGACTCTGCTGCACCCCAAAGCACAACTTGGCCAGAGACTAGTCCCAGATTCAAGACAGGGTTACCTTCAGCAACA ACCACTGTTTCAACCTCTGCCACTTCTCTCTCTGCTACTGTAATGGTCTCTAAATTCACTTCTCCAGCAACTAGTTCCATGGAAGCAACT TCTATCAGGGAACCATCAACAACCATCCTCACAACAGAGACCACGAATGGCCCAGGCTCTATGGCTGTGGCTTCTACCAACATCCCAATT GGAAAGGGCTACATTACTGAAGGAAGATTGGACACAAGCCATCTGCCCATTGGAACCACAGCTTCCTCTGAGACATCTATGGATTTTACC ATGGCCAAAGAAAGTGTCTCAATGTCAGTATCTCCATCTCAGTCCATGGATGCTGCTGGCTCAAGCACTCCAGGAAGGACAAGCCAATTC GTTGACACATTTTCTGATGATGTCTATCATTTAACATCCAGAGAAATTACAATACCTAGAGATGGAACAAGCTCAGCTCTGACTCCACAA ATGACTGCAACTCACCCTCCATCTCCTGATCCTGGCTCTGCTAGAAGCACCTGGCTTGGCATCTTGTCCTCATCTCCTTCTTCTCCTACT CCCAAAGTCACAATGAGCTCCACATTTTCAACTCAGAGAGTCACCACAAGCATGATAATGGACACAGTTGAAACTAGTCGGTGGAACATG CCCAACTTACCTTCCACGACTTCCTTGACACCAAGTAATATTCCAACAAGTGGTGCCATAGGAAAAAGCACCCTGGTTCCCTTGGACACT CCATCTCCAGCCACATCATTGGAGGCATCAGAAGGGGGACTTCCAACCCTCAGCACCTACCCTGAATCAACAAACACACCCAGCATCCAC CTCGGAGCACACGCTAGTTCAGAAAGTCCAAGCACCATCAAACTTACCATGGCTTCAGTAGTAAAACCTGGCTCTTACACACCTCTCACC TTCCCCTCAATAGAGACCCACATTCATGTATCAACAGCCAGAATGGCTTACTCTTCTGGGTCTTCACCTGAGATGACAGCTCCTGGAGAG ACTAACACTGGTAGTACCTGGGACCCCACCACCTACATCACCACTACGGATCCTAAGGATACAAGTTCAGCTCAGGTCTCTACACCCCAC TCAGTGAGGACACTCAGAACCACAGAAAACCATCCAAAGACAGAGTCCGCCACCCCAGCTGCTTACTCTGGAAGTCCTAAAATCTCAAGT TCACCCAATCTCACCAGTCCGGCCACAAAAGCATGGACCATCACAGACACAACTGAACACTCCACTCAATTACATTACACAAAATTGGCA GAAAAATCATCTGGATTTGAGACACAGTCAGCTCCAGGACCTGTCTCTGTAGTAATCCCTACCTCCCCTACCATTGGAAGCAGCACATTG GAACTAACTTCTGATGTCCCAGGGGAACCCCTGGTCCTTGCTCCCAGTGAGCAGACCACAATCACTCTCCCCATGGCAACATGGCTGAGT ACCAGTTTGACAGAGGAAATGGCTTCAACAGACCTTGATATTTCAAGTCCAAGTTCACCCATGAGTACATTTGCTATTTTTCCACCTATG TCCACACCTTCTCATGAACTTTCAAAGTCAGAGGCAGATACCAGTGCCATTAGAAATACAGATTCAACAACGTTGGATCAGCACCTAGGA ATCAGGAGTTTGGGCAGAACTGGGGACTTAACAACTGTTCCTATCACCCCACTGACAACCACGTGGACCAGTGTGATTGAACACTCAACA CAAGCACAGGACACCCTTTCTGCAACGATGAGTCCTACTCACGTGACACAGTCACTCAAAGATCAAACATCTATACCAGCCTCAGCATCC CCTTCCCATCTTACTGAAGTCTACCCTGAGCTCGGGACACAAGGGAGAAGCTCCTCTGAGGCAACCACTTTTTGGAAACCATCTACAGAC ACACTGTCCAGAGAGATTGAGACTGGCCCAACAAACATTCAATCCACTCCACCCATGGACAACACAACAACAGGGAGCAGTAGTAGTGGA GTCACCCTGGGCATAGCCCACCTTCCCATAGGAACATCCTCCCCAGCTGAGACATCCACAAACATGGCACTGGAAAGAAGAAGTTCTACA GCCACTGTCTCTATGGCTGGGACAATGGGACTCCTTGTTACTAGTGCTCCAGGAAGAAGCATCAGCCAGTCATTAGGAAGAGTTTCCTCT GTCCTTTCTGAGTCAACTACTGAAGGAGTCACAGATTCTAGTAAGGGAAGCAGCCCAAGGCTGAACACACAGGGAAATACAGCTCTCTCC TCCTCTCTTGAACCCAGCTATGCTGAAGGAAGCCAGATGAGCACAAGCATCCCTCTAACCTCATCTCCTACAACTCCTGATGTGGAATTC ATAGGGGGCAGCACATTTTGGACCAAGGAGGTCACCACAGTTATGACCTCAGACATCTCCAAGTCTTCAGCAAGGACAGAGTCCAGCTCA GCTACCCTTATGTCCACAGCTTTGGGAAGCACTGAAAATACAGGAAAAGAAAAACTCAGAACTGCCTCTATGGATCTTCCATCTCCAACT CCATCAATGGAGGTGACACCATGGATTTCTCTCACTCTCAGTAATGCCCCCAATACCACAGATTCACTTGACCTCAGCCATGGGGTGCAC ACCAGCTCTGCAGGGACTTTGGCCACTGACAGGTCATTGAATACTGGTGTCACTAGAGCCTCCAGATTGGAAAACGGCTCTGATACCTCT TCTAAGTCCCTGTCTATGGGAAACAGCACTCACACTTCCATGACTTACACAGAGAAGAGTGAAGTGTCTTCTTCAATCCATCCCCGACCT GAGACCTCAGCTCCTGGAGCAGAGACCACTTTGACTTCCACTCCTGGAAACAGGGCCATAAGCTTAACATTGCCTTTTTCATCCATTCCA GTGGAAGAAGTCATTTCTACAGGCATAACCTCAGGACCAGACATCAACTCAGCACCCATGACACATTCTCCCATCACCCCACCAACAATT GTATGGACCAGTACAGGCACAATTGAACAGTCCACTCAACCACTACATGCAGTTTCTTCAGAAAAAGTTTCTGTGCAGACACAGTCAACT CCATATGTCAACTCTGTGGCAGTGTCTGCTTCCCCTACCCATGAGAATTCAGTCTCTTCTGGAAGCAGCACATCCTCTCCATATTCCTCA GCCTCACTTGAATCCTTGGATTCCACAATCAGTAGGAGGAATGCAATCACTTCCTGGCTATGGGACCTCACTACATCTCTCCCCACTACA ACTTGGCCAAGTACTAGTTTATCTGAGGCACTGTCCTCAGGCCATTCTGGGGTTTCAAACCCAAGTTCAACTACGACTGAATTTCCACTC TTTTCAGCTGCATCCACATCTGCTGCTAAGCAAAGAAATCCAGAAACAGAGACCCATGGTCCCCAGAATACAGCCGCGAGTACTTTGAAC ACTGATGCATCCTCGGTCACAGGTCTTTCTGAGACTCCTGTGGGGGCAAGTATCAGCTCTGAAGTCCCTCTTCCAATGGCCATAACTTCT AGATCAGATGTTTCTGGCCTTACATCTGAGAGTACTGCTAACCCGAGTTTAGGCACAGCCTCTTCAGCAGGGACCAAATTAACTAGGACA ATATCCCTGCCCACTTCAGAGTCTTTGGTTTCCTTTAGAATGAACAAGGATCCATGGACAGTGTCAATCCCTTTGGGGTCCCATCCAACT ACTAATACAGAAACAAGCATCCCAGTAAACAGCGCAGGTCCACCTGGCTTGTCCACAGTAGCATCAGATGTAATTGACACACCTTCAGAT GGGGCTGAGAGTATTCCCACTGTCTCCTTTTCCCCCTCCCCTGATACTGAAGTGACAACTATCTCACATTTCCCAGAAAAGACAACTCAT TCATTTAGAACCATTTCATCTCTCACTCATGAGTTGACTTCAAGAGTGACACCTATTCCTGGGGATTGGATGAGTTCAGCTATGTCTACA AAGCCCACAGGAGCCAGTCCCTCCATTACACTGGGAGAGAGAAGGACAATCACCTCTGCTGCTCCAACCACTTCCCCCATAGTTCTCACT GCTAGTTTCACAGAGACCAGCACAGTTTCACTGGATAATGAAACTACAGTAAAAACCTCAGATATCCTTGACGCACGGAAAACAAATGAG CTCCCCTCAGATAGCAGTTCTTCTTCTGATCTGATCAACACCTCCATAGCTTCTTCAACTATGGATGTCACTAAAACAGCCTCCATCAGT CCCACTAGCATCTCAGGAATGACAGCAAGTTCCTCCCCATCTCTCTTCTCTTCAGATAGACCCCAGGTTCCCACATCTACAACAGAGACA AATACAGCCACCTCTCCATCTGTTTCCAGTAACACCTATTCTCTTGATGGGGGCTCCAATGTGGGTGGCACTCCATCCACTTTACCACCC TTTACAATCACCCACCCTGTCGAGACAAGCTCGGCCCTATTAGCCTGGTCTAGACCAGTAAGAACTTTCAGCACCATGGTCAGCACTGAC ACTGCCTCCGGAGAAAATCCTACCTCTAGCAATTCTGTGGTGACTTCTGTTCCAGCACCAGGTACATGGACCAGTGTAGGCAGTACTACT GACTTACCTGCCATGGGCTTTCTCAAGACAAGTCCTGCAGGAGAGGCACACTCACTTCTAGCATCAACTATTGAACCAGCCACTGCCTTC ACTCCCCATCTCTCAGCAGCAGTGGTCACTGGATCCAGTGCTACATCAGAAGCCAGTCTTCTCACTACGAGTGAAAGCAAAGCCATTCAT TCTTCACCACAGACCCCAACTACACCCACCTCTGGAGCAAACTGGGAAACTTCAGCTACTCCTGAGAGCCTTTTGGTAGTCACTGAGACT TCAGACACAACACTTACCTCAAAGATTTTGGTCACAGATACCATCTTGTTTTCAACTGTGTCCACGCCACCTTCTAAATTTCCAAGTACG GGGACTCTGTCTGGAGCTTCCTTCCCTACTTTACTCCCGGACACTCCAGCCATCCCTCTCACTGCCACTGAGCCAACAAGTTCATTAGCT ACATCCTTTGATTCCACCCCACTGGTGACTATAGCTTCGGATAGTCTTGGCACAGTCCCAGAGACTACCCTGACCATGTCAGAGACCTCA AATGGTGATGCACTGGTTCTTAAGACAGTAAGTAACCCAGATAGGAGCATCCCTGGAATCACTATCCAAGGAGTAACAGAAAGTCCACTC CATCCTTCTTCCACTTCCCCCTCTAAGATTGTTGCTCCACGGAATACAACCTATGAAGGTTCGATCACAGTGGCACTTTCTACTTTGCCT GCGGGAACTACTGGTTCCCTTGTATTCAGTCAGAGTTCTGAAAACTCAGAGACAACGGCTTTGGTAGACTCATCAGCTGGGCTTGAGAGG GCATCTGTGATGCCACTAACCACAGGAAGCCAGGGTATGGCTAGCTCTGGAGGAATCAGAAGTGGGTCCACTCACTCAACTGGAACCAAA ACATTTTCTTCTCTCCCTCTGACCATGAACCCAGGTGAGGTTACAGCCATGTCTGAAATCACCACGAACAGACTGACAGCTACTCAATCA ACAGCACCCAAAGGGATACCTGTGAAGCCCACCAGTGCTGAGTCAGGCCTCCTAACACCTGTCTCTGCCTCCTCAAGCCCATCAAAGGCC TTTGCCTCACTGACTACAGCTCCCCCAACTTGGGGGATCCCACAGTCTACCTTGACATTTGAGTTTTCTGAGGTCCCAAGTTTGGATACT AAGTCCGCTTCTTTACCAACTCCTGGACAGTCCCTGAACACCATTCCAGACTCAGATGCAAGCACAGCATCTTCCTCACTGTCCAAGTCT CCAGAAAAAAACCCAAGGGCAAGGATGATGACTTCCACAAAGGCCATAAGTGCAAGCTCATTTCAATCAACAGGTTTTACTGAAACCCCT GAGGGATCTGCCTCCCCTTCTATGGCAGGGCATGAACCCAGAGTCCCCACTTCAGGAACAGGGGACCCTAGATATGCCTCAGAGAGCATG TCTTATCCAGACCCAAGCAAGGCATCATCAGCTATGACATCGACCTCTCTTGCATCAAAACTCACAACTCTCTTCAGCACAGGTCAAGCA GCAAGGTCTGGTTCTAGTTCCTCTCCCATAAGCCTATCCACTGAGAAAGAAACAAGCTTCCTTTCCCCCACTGCATCCACCTCCAGAAAG ACTTCACTATTTCTTGGGCCTTCCATGGCAAGGCAGCCCAACATATTGGTGCATCTTCAGACTTCAGCTCTGACACTTTCTCCAACATCC ACTCTAAATATGTCCCAGGAGGAGCCTCCTGAGTTAACCTCAAGCCAGACCATTGCAGAAGAAGAGGGAACAACAGCTGAAACACAGACG TTAACCTTCACACCATCTGAGACCCCAACATCCTTGTTACCTGTCTCTTCTCCCACAGAACCCACAGCCAGAAGAAAGAGTTCTCCAGAA ACATGGGCAAGCTCTATTTCAGTTCCTGCCAAGACCTCCTTGGTTGAAACAACTGATGGAACGCTAGTGACCACCATAAAGATGTCAAGC CAGGCAGCACAAGGAAATTCCACGTGGCCTGCCCCAGCAGAGGAGACGGGGAGCAGTCCAGCAGAATATTTAAAAGATGCTTCAAAGAAG ATGAAAAATGGGCTAATGTTTGTAAAACTGGTTAACCCCTGTTCAGGAGAAGGAGCCATTTACTTGTTCAATATGTGTCTACAGCAGCTG TTTGAAGTAAAAGTTTTCAAGGAAAAACACCATTCTTGGTTTATAAATCAATCAGTTCAATCAGGAGGTCTTCTCCATTTTGCCACACCT GTGGATCCTCTATTTCTGCTTCTCCACTACCTCATAAAGGCTGATAAGGAGGGGAAGTTTCAGCCCCTTGATCAAGTTGTGGTGGATAAC GTGTTTCCAAATTGCATCTTGTTGCTGAAACTTCCTGGACTTGAGAAGTTACTTCATCATGTGACAGAGGAAAAAGGTAATCCAGAAATA GACAACAAGAAATATTACAAGTACAGCAAAGAGAAGACATTAAAGTGGCTGGAAAAAAAGGTTAATCAAACTGTGGCAGCATTAAAAACC AATAATGTGAATGTCAGTTCCCGGGTACAGTCAACTGCATTTTTCTCTGGTGACCAAGCTTCCACTGACAAGGAAGAGGATTATATTCGT TATGCCCATGGTCTGATATCTGACTACATCCCTAAAGAATTAAGTGATGACTTATCTAAATACTTAAAGCTTCCAGAACCTTCAGCCTCA TTGCCAAATCCTCCATCAAAGAAAATAAAGTTATCAGATGAGCCTGTAGAAGCAAAAGAAGATTACACTAAGTTTAATACTAAAGATTTG AAGACTGAAAAGAAAAATAGCAAAATGACTGCAGCTCAGAAGGCTTTGGCTAAAGTTGACAAGAGTGGAATGAAAAGTATTGATACCTTT TTTGGGGTAAAAAATAAAAAAAAAATTGGAAAGGTTTGAAACTTTGAAAATAAAATCTAGCAAAAATATTTGCTTTTTACATGTTTCAGT TTGTCCTTCCTGACTGTTAATGACTACCTTTGGTTGGGGGAAGGAAGAGGCCAATTTCATGTTCTCTTAAACATTTCTTTGCATTTGGTT TTTGTGTTCCTGAACAAAATATGGGAAAGTGTCTAACTTCATGGCTATGGCCTTTTGGAGTCTCATCTGACATAATGAAAAGTAATCACT TGAAGAGAATTAACATATAGCATCATGATTTTCTCAATAAACTGATGTGTGACAATGTTA >55996_55996_3_MUC16-RNASEH2B_MUC16_chr19_9080451_ENST00000397910_RNASEH2B_chr13_51501543_ENST00000336617_length(amino acids)=3519AA_BP=3223 MRNFGVSGSSEALQRPPSLRGFFLDLHPEANVDLSMLKPSGLPGSSSPTRSLMTGSRSTKATPEMDSGLTGATLSPKTSTGAIVVTEHTL PFTSPDKTLASPTSSVVGRTTQSLGVMSSALPESTSRGMTHSEQRTSPSLSPQVNGTPSRNYPATSMVSGLSSPRTRTSSTEGNFTKEAS TYTLTVETTSGPVTEKYTVPTETSTTEGDSTETPWDTRYIPVKITSPMKTFADSTASKENAPVSMTPAETTVTDSHTPGRTNPSFGTLYS SFLDLSPKGTPNSRGETSLELILSTTGYPFSSPEPGSAGHSRISTSAPLSSSASVLDNKISETSIFSGQSLTSPLSPGVPEARASTMPNS AIPFSMTLSNAETSAERVRSTISSLGTPSISTKQTAETILTFHAFAETMDIPSTHIAKTLASEWLGSPGTLGGTSTSALTTTSPSTTLVS EETNTHHSTSGKETEGTLNTSMTPLETSAPGEESEMTATLVPTLGFTTLDSKIRSPSQVSSSHPTRELRTTGSTSGRQSSSTAAHGSSDI LRATTSSTSKASSWTSESTAQQFSEPQHTQWVETSPSMKTERPPASTSVAAPITTSVPSVVSGFTTLKTSSTKGIWLEETSADTLIGEST AGPTTHQFAVPTGISMTGGSSTRGSQGTTHLLTRATASSETSADLTLATNGVPVSVSPAVSKTAAGSSPPGGTKPSYTMVSSVIPETSSL QSSAFREGTSLGLTPLNTRHPFSSPEPDSAGHTKISTSIPLLSSASVLEDKVSATSTFSHHKATSSITTGTPEISTKTKPSSAVLSSMTL SNAATSPERVRNATSPLTHPSPSGEETAGSVLTLSTSAETTDSPNIHPTGTLTSESSESPSTLSLPSVSGVKTTFSSSTPSTHLFTSGEE TEETSNPSVSQPETSVSRVRTTLASTSVPTPVFPTMDTWPTRSAQFSSSHLVSELRATSSTSVTNSTGSALPKISHLTGTATMSQTNRDT FNDSAAPQSTTWPETSPRFKTGLPSATTTVSTSATSLSATVMVSKFTSPATSSMEATSIREPSTTILTTETTNGPGSMAVASTNIPIGKG YITEGRLDTSHLPIGTTASSETSMDFTMAKESVSMSVSPSQSMDAAGSSTPGRTSQFVDTFSDDVYHLTSREITIPRDGTSSALTPQMTA THPPSPDPGSARSTWLGILSSSPSSPTPKVTMSSTFSTQRVTTSMIMDTVETSRWNMPNLPSTTSLTPSNIPTSGAIGKSTLVPLDTPSP ATSLEASEGGLPTLSTYPESTNTPSIHLGAHASSESPSTIKLTMASVVKPGSYTPLTFPSIETHIHVSTARMAYSSGSSPEMTAPGETNT GSTWDPTTYITTTDPKDTSSAQVSTPHSVRTLRTTENHPKTESATPAAYSGSPKISSSPNLTSPATKAWTITDTTEHSTQLHYTKLAEKS SGFETQSAPGPVSVVIPTSPTIGSSTLELTSDVPGEPLVLAPSEQTTITLPMATWLSTSLTEEMASTDLDISSPSSPMSTFAIFPPMSTP SHELSKSEADTSAIRNTDSTTLDQHLGIRSLGRTGDLTTVPITPLTTTWTSVIEHSTQAQDTLSATMSPTHVTQSLKDQTSIPASASPSH LTEVYPELGTQGRSSSEATTFWKPSTDTLSREIETGPTNIQSTPPMDNTTTGSSSSGVTLGIAHLPIGTSSPAETSTNMALERRSSTATV SMAGTMGLLVTSAPGRSISQSLGRVSSVLSESTTEGVTDSSKGSSPRLNTQGNTALSSSLEPSYAEGSQMSTSIPLTSSPTTPDVEFIGG STFWTKEVTTVMTSDISKSSARTESSSATLMSTALGSTENTGKEKLRTASMDLPSPTPSMEVTPWISLTLSNAPNTTDSLDLSHGVHTSS AGTLATDRSLNTGVTRASRLENGSDTSSKSLSMGNSTHTSMTYTEKSEVSSSIHPRPETSAPGAETTLTSTPGNRAISLTLPFSSIPVEE VISTGITSGPDINSAPMTHSPITPPTIVWTSTGTIEQSTQPLHAVSSEKVSVQTQSTPYVNSVAVSASPTHENSVSSGSSTSSPYSSASL ESLDSTISRRNAITSWLWDLTTSLPTTTWPSTSLSEALSSGHSGVSNPSSTTTEFPLFSAASTSAAKQRNPETETHGPQNTAASTLNTDA SSVTGLSETPVGASISSEVPLPMAITSRSDVSGLTSESTANPSLGTASSAGTKLTRTISLPTSESLVSFRMNKDPWTVSIPLGSHPTTNT ETSIPVNSAGPPGLSTVASDVIDTPSDGAESIPTVSFSPSPDTEVTTISHFPEKTTHSFRTISSLTHELTSRVTPIPGDWMSSAMSTKPT GASPSITLGERRTITSAAPTTSPIVLTASFTETSTVSLDNETTVKTSDILDARKTNELPSDSSSSSDLINTSIASSTMDVTKTASISPTS ISGMTASSSPSLFSSDRPQVPTSTTETNTATSPSVSSNTYSLDGGSNVGGTPSTLPPFTITHPVETSSALLAWSRPVRTFSTMVSTDTAS GENPTSSNSVVTSVPAPGTWTSVGSTTDLPAMGFLKTSPAGEAHSLLASTIEPATAFTPHLSAAVVTGSSATSEASLLTTSESKAIHSSP QTPTTPTSGANWETSATPESLLVVTETSDTTLTSKILVTDTILFSTVSTPPSKFPSTGTLSGASFPTLLPDTPAIPLTATEPTSSLATSF DSTPLVTIASDSLGTVPETTLTMSETSNGDALVLKTVSNPDRSIPGITIQGVTESPLHPSSTSPSKIVAPRNTTYEGSITVALSTLPAGT TGSLVFSQSSENSETTALVDSSAGLERASVMPLTTGSQGMASSGGIRSGSTHSTGTKTFSSLPLTMNPGEVTAMSEITTNRLTATQSTAP KGIPVKPTSAESGLLTPVSASSSPSKAFASLTTAPPTWGIPQSTLTFEFSEVPSLDTKSASLPTPGQSLNTIPDSDASTASSSLSKSPEK NPRARMMTSTKAISASSFQSTGFTETPEGSASPSMAGHEPRVPTSGTGDPRYASESMSYPDPSKASSAMTSTSLASKLTTLFSTGQAARS GSSSSPISLSTEKETSFLSPTASTSRKTSLFLGPSMARQPNILVHLQTSALTLSPTSTLNMSQEEPPELTSSQTIAEEEGTTAETQTLTF TPSETPTSLLPVSSPTEPTARRKSSPETWASSISVPAKTSLVETTDGTLVTTIKMSSQAAQGNSTWPAPAEETGSSPAEYLKDASKKMKN GLMFVKLVNPCSGEGAIYLFNMCLQQLFEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDNVFP NCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKTNNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAH GLISDYIPKELSDDLSKYLKLPEPSASLPNPPSKKIKLSDEPVEAKEDYTKFNTKDLKTEKKNSKMTAAQKALAKVDKSGMKSIDTFFGV KNKKKIGKV -------------------------------------------------------------- >55996_55996_4_MUC16-RNASEH2B_MUC16_chr19_9080451_ENST00000397910_RNASEH2B_chr13_51501543_ENST00000422660_length(transcript)=10986nt_BP=9784nt AAGCGTTGCACAATTCCCCCAACCTCCATACATACGGCAGCTCTTCTAGACACAGGTTTTCCCAGGTCAAATGCGGGGACCCCAGCCATA TCTCCCACCCTGAGAAATTTTGGAGTTTCAGGGAGCTCAGAAGCTCTGCAGAGGCCACCCTCTCTGAGGGGATTCTTCTTAGACCTCCAT CCAGAGGCAAATGTTGACCTGTCCATGCTGAAACCCTCAGGCCTTCCTGGGTCATCTTCTCCCACCCGCTCCTTGATGACAGGGAGCAGG AGCACTAAAGCCACACCAGAAATGGATTCAGGACTGACAGGAGCCACCTTGTCACCTAAGACATCTACAGGTGCAATCGTGGTGACAGAA CATACTCTGCCCTTTACTTCCCCAGATAAGACCTTGGCCAGTCCTACATCTTCGGTTGTGGGAAGAACCACCCAGTCTTTGGGGGTGATG TCCTCTGCTCTCCCTGAGTCAACCTCTAGAGGAATGACACACTCCGAGCAAAGAACCAGCCCATCGCTGAGTCCCCAGGTCAATGGAACT CCCTCTAGGAACTACCCTGCTACAAGCATGGTTTCAGGATTGAGTTCCCCAAGGACCAGGACCAGTTCCACAGAAGGAAATTTTACCAAA GAAGCATCTACATACACACTCACTGTAGAGACCACAAGTGGCCCAGTCACTGAGAAGTACACAGTCCCCACTGAGACCTCAACAACTGAA GGTGACAGCACAGAGACCCCCTGGGACACAAGATATATTCCTGTAAAAATCACATCTCCAATGAAAACATTTGCAGATTCAACTGCATCC AAGGAAAATGCCCCAGTGTCTATGACTCCAGCTGAGACCACAGTTACTGACTCACATACTCCAGGAAGGACAAACCCATCATTTGGGACA CTTTATTCTTCCTTCCTTGACCTATCACCTAAAGGGACCCCAAATTCCAGAGGTGAAACAAGCCTGGAACTGATTCTATCAACCACTGGA TATCCCTTCTCCTCTCCTGAACCTGGCTCTGCAGGACACAGCAGAATAAGTACCAGTGCGCCTTTGTCATCATCTGCTTCAGTTCTCGAT AATAAAATATCAGAGACCAGCATATTCTCAGGCCAGAGTCTCACCTCCCCTCTGTCTCCTGGGGTGCCCGAGGCCAGAGCCAGCACAATG CCCAACTCAGCTATCCCTTTTTCCATGACACTAAGCAATGCAGAAACAAGTGCCGAAAGGGTCAGAAGCACAATTTCCTCTCTGGGGACT CCATCAATATCCACAAAGCAGACAGCAGAGACTATCCTTACCTTCCATGCCTTCGCTGAGACCATGGATATACCCAGCACCCACATAGCC AAGACTTTGGCTTCAGAATGGTTGGGAAGTCCAGGTACCCTTGGTGGCACCAGCACTTCAGCGCTGACAACCACATCTCCATCTACCACT TTAGTCTCAGAGGAGACCAACACCCATCACTCCACGAGTGGAAAGGAAACAGAAGGAACTTTGAATACATCTATGACTCCACTTGAGACC TCTGCTCCTGGAGAAGAGTCCGAAATGACTGCCACCTTGGTCCCCACTCTAGGTTTTACAACTCTTGACAGCAAGATCAGAAGTCCATCT CAGGTCTCTTCATCCCACCCAACAAGAGAGCTCAGAACCACAGGCAGCACCTCTGGGAGGCAGAGTTCCAGCACAGCTGCCCACGGGAGC TCTGACATCCTGAGGGCAACCACTTCCAGCACCTCAAAAGCATCATCATGGACCAGTGAAAGCACAGCTCAGCAATTTAGTGAACCCCAG CACACACAGTGGGTGGAGACAAGTCCTAGCATGAAAACAGAGAGACCCCCAGCATCAACCAGTGTGGCAGCCCCTATCACCACTTCTGTT CCCTCAGTGGTCTCTGGCTTCACCACCCTGAAGACCAGCTCCACAAAAGGGATTTGGCTTGAAGAAACATCTGCAGACACACTCATCGGA GAATCCACAGCTGGCCCAACCACCCATCAGTTTGCTGTTCCCACTGGGATTTCAATGACAGGAGGCAGCAGCACCAGGGGAAGCCAGGGC ACAACCCACCTACTCACCAGAGCCACAGCATCATCTGAGACATCCGCAGATTTGACTCTGGCCACGAACGGTGTCCCAGTCTCCGTGTCT CCAGCAGTGAGCAAGACGGCTGCTGGCTCAAGTCCTCCAGGAGGGACAAAGCCATCATATACAATGGTTTCTTCTGTCATCCCTGAGACA TCATCTCTACAGTCCTCAGCTTTCAGGGAAGGAACCAGCCTGGGACTGACTCCATTAAACACTAGACATCCCTTCTCTTCCCCTGAACCA GACTCTGCAGGACACACCAAGATAAGCACCAGCATTCCTCTGTTGTCATCTGCTTCAGTTCTTGAGGATAAAGTGTCAGCGACCAGCACA TTCTCACACCACAAAGCCACCTCATCTATTACCACAGGGACTCCTGAAATCTCAACAAAGACAAAGCCCAGCTCAGCCGTTCTTTCCTCC ATGACCCTAAGCAATGCAGCAACAAGTCCTGAAAGAGTCAGAAATGCAACTTCCCCTCTGACTCATCCATCTCCATCAGGGGAAGAGACA GCAGGGAGTGTCCTCACTCTCAGCACCTCTGCTGAGACTACAGACTCACCTAACATCCACCCAACTGGGACACTGACTTCAGAATCGTCA GAGAGTCCTAGCACTCTCAGCCTCCCAAGTGTCTCTGGAGTCAAAACCACATTTTCTTCATCTACTCCTTCCACTCATCTATTTACTAGT GGAGAAGAAACAGAGGAAACTTCGAATCCATCTGTGTCTCAACCTGAGACTTCTGTTTCCAGAGTAAGGACCACCTTGGCCAGCACCTCT GTCCCTACCCCAGTATTCCCCACCATGGACACCTGGCCTACACGTTCAGCTCAGTTCTCTTCATCCCACCTAGTGAGTGAGCTCAGAGCT ACGAGCAGTACCTCAGTTACAAACTCAACTGGTTCAGCTCTTCCTAAAATATCTCACCTCACTGGGACGGCAACAATGTCACAGACCAAT AGAGACACGTTTAATGACTCTGCTGCACCCCAAAGCACAACTTGGCCAGAGACTAGTCCCAGATTCAAGACAGGGTTACCTTCAGCAACA ACCACTGTTTCAACCTCTGCCACTTCTCTCTCTGCTACTGTAATGGTCTCTAAATTCACTTCTCCAGCAACTAGTTCCATGGAAGCAACT TCTATCAGGGAACCATCAACAACCATCCTCACAACAGAGACCACGAATGGCCCAGGCTCTATGGCTGTGGCTTCTACCAACATCCCAATT GGAAAGGGCTACATTACTGAAGGAAGATTGGACACAAGCCATCTGCCCATTGGAACCACAGCTTCCTCTGAGACATCTATGGATTTTACC ATGGCCAAAGAAAGTGTCTCAATGTCAGTATCTCCATCTCAGTCCATGGATGCTGCTGGCTCAAGCACTCCAGGAAGGACAAGCCAATTC GTTGACACATTTTCTGATGATGTCTATCATTTAACATCCAGAGAAATTACAATACCTAGAGATGGAACAAGCTCAGCTCTGACTCCACAA ATGACTGCAACTCACCCTCCATCTCCTGATCCTGGCTCTGCTAGAAGCACCTGGCTTGGCATCTTGTCCTCATCTCCTTCTTCTCCTACT CCCAAAGTCACAATGAGCTCCACATTTTCAACTCAGAGAGTCACCACAAGCATGATAATGGACACAGTTGAAACTAGTCGGTGGAACATG CCCAACTTACCTTCCACGACTTCCTTGACACCAAGTAATATTCCAACAAGTGGTGCCATAGGAAAAAGCACCCTGGTTCCCTTGGACACT CCATCTCCAGCCACATCATTGGAGGCATCAGAAGGGGGACTTCCAACCCTCAGCACCTACCCTGAATCAACAAACACACCCAGCATCCAC CTCGGAGCACACGCTAGTTCAGAAAGTCCAAGCACCATCAAACTTACCATGGCTTCAGTAGTAAAACCTGGCTCTTACACACCTCTCACC TTCCCCTCAATAGAGACCCACATTCATGTATCAACAGCCAGAATGGCTTACTCTTCTGGGTCTTCACCTGAGATGACAGCTCCTGGAGAG ACTAACACTGGTAGTACCTGGGACCCCACCACCTACATCACCACTACGGATCCTAAGGATACAAGTTCAGCTCAGGTCTCTACACCCCAC TCAGTGAGGACACTCAGAACCACAGAAAACCATCCAAAGACAGAGTCCGCCACCCCAGCTGCTTACTCTGGAAGTCCTAAAATCTCAAGT TCACCCAATCTCACCAGTCCGGCCACAAAAGCATGGACCATCACAGACACAACTGAACACTCCACTCAATTACATTACACAAAATTGGCA GAAAAATCATCTGGATTTGAGACACAGTCAGCTCCAGGACCTGTCTCTGTAGTAATCCCTACCTCCCCTACCATTGGAAGCAGCACATTG GAACTAACTTCTGATGTCCCAGGGGAACCCCTGGTCCTTGCTCCCAGTGAGCAGACCACAATCACTCTCCCCATGGCAACATGGCTGAGT ACCAGTTTGACAGAGGAAATGGCTTCAACAGACCTTGATATTTCAAGTCCAAGTTCACCCATGAGTACATTTGCTATTTTTCCACCTATG TCCACACCTTCTCATGAACTTTCAAAGTCAGAGGCAGATACCAGTGCCATTAGAAATACAGATTCAACAACGTTGGATCAGCACCTAGGA ATCAGGAGTTTGGGCAGAACTGGGGACTTAACAACTGTTCCTATCACCCCACTGACAACCACGTGGACCAGTGTGATTGAACACTCAACA CAAGCACAGGACACCCTTTCTGCAACGATGAGTCCTACTCACGTGACACAGTCACTCAAAGATCAAACATCTATACCAGCCTCAGCATCC CCTTCCCATCTTACTGAAGTCTACCCTGAGCTCGGGACACAAGGGAGAAGCTCCTCTGAGGCAACCACTTTTTGGAAACCATCTACAGAC ACACTGTCCAGAGAGATTGAGACTGGCCCAACAAACATTCAATCCACTCCACCCATGGACAACACAACAACAGGGAGCAGTAGTAGTGGA GTCACCCTGGGCATAGCCCACCTTCCCATAGGAACATCCTCCCCAGCTGAGACATCCACAAACATGGCACTGGAAAGAAGAAGTTCTACA GCCACTGTCTCTATGGCTGGGACAATGGGACTCCTTGTTACTAGTGCTCCAGGAAGAAGCATCAGCCAGTCATTAGGAAGAGTTTCCTCT GTCCTTTCTGAGTCAACTACTGAAGGAGTCACAGATTCTAGTAAGGGAAGCAGCCCAAGGCTGAACACACAGGGAAATACAGCTCTCTCC TCCTCTCTTGAACCCAGCTATGCTGAAGGAAGCCAGATGAGCACAAGCATCCCTCTAACCTCATCTCCTACAACTCCTGATGTGGAATTC ATAGGGGGCAGCACATTTTGGACCAAGGAGGTCACCACAGTTATGACCTCAGACATCTCCAAGTCTTCAGCAAGGACAGAGTCCAGCTCA GCTACCCTTATGTCCACAGCTTTGGGAAGCACTGAAAATACAGGAAAAGAAAAACTCAGAACTGCCTCTATGGATCTTCCATCTCCAACT CCATCAATGGAGGTGACACCATGGATTTCTCTCACTCTCAGTAATGCCCCCAATACCACAGATTCACTTGACCTCAGCCATGGGGTGCAC ACCAGCTCTGCAGGGACTTTGGCCACTGACAGGTCATTGAATACTGGTGTCACTAGAGCCTCCAGATTGGAAAACGGCTCTGATACCTCT TCTAAGTCCCTGTCTATGGGAAACAGCACTCACACTTCCATGACTTACACAGAGAAGAGTGAAGTGTCTTCTTCAATCCATCCCCGACCT GAGACCTCAGCTCCTGGAGCAGAGACCACTTTGACTTCCACTCCTGGAAACAGGGCCATAAGCTTAACATTGCCTTTTTCATCCATTCCA GTGGAAGAAGTCATTTCTACAGGCATAACCTCAGGACCAGACATCAACTCAGCACCCATGACACATTCTCCCATCACCCCACCAACAATT GTATGGACCAGTACAGGCACAATTGAACAGTCCACTCAACCACTACATGCAGTTTCTTCAGAAAAAGTTTCTGTGCAGACACAGTCAACT CCATATGTCAACTCTGTGGCAGTGTCTGCTTCCCCTACCCATGAGAATTCAGTCTCTTCTGGAAGCAGCACATCCTCTCCATATTCCTCA GCCTCACTTGAATCCTTGGATTCCACAATCAGTAGGAGGAATGCAATCACTTCCTGGCTATGGGACCTCACTACATCTCTCCCCACTACA ACTTGGCCAAGTACTAGTTTATCTGAGGCACTGTCCTCAGGCCATTCTGGGGTTTCAAACCCAAGTTCAACTACGACTGAATTTCCACTC TTTTCAGCTGCATCCACATCTGCTGCTAAGCAAAGAAATCCAGAAACAGAGACCCATGGTCCCCAGAATACAGCCGCGAGTACTTTGAAC ACTGATGCATCCTCGGTCACAGGTCTTTCTGAGACTCCTGTGGGGGCAAGTATCAGCTCTGAAGTCCCTCTTCCAATGGCCATAACTTCT AGATCAGATGTTTCTGGCCTTACATCTGAGAGTACTGCTAACCCGAGTTTAGGCACAGCCTCTTCAGCAGGGACCAAATTAACTAGGACA ATATCCCTGCCCACTTCAGAGTCTTTGGTTTCCTTTAGAATGAACAAGGATCCATGGACAGTGTCAATCCCTTTGGGGTCCCATCCAACT ACTAATACAGAAACAAGCATCCCAGTAAACAGCGCAGGTCCACCTGGCTTGTCCACAGTAGCATCAGATGTAATTGACACACCTTCAGAT GGGGCTGAGAGTATTCCCACTGTCTCCTTTTCCCCCTCCCCTGATACTGAAGTGACAACTATCTCACATTTCCCAGAAAAGACAACTCAT TCATTTAGAACCATTTCATCTCTCACTCATGAGTTGACTTCAAGAGTGACACCTATTCCTGGGGATTGGATGAGTTCAGCTATGTCTACA AAGCCCACAGGAGCCAGTCCCTCCATTACACTGGGAGAGAGAAGGACAATCACCTCTGCTGCTCCAACCACTTCCCCCATAGTTCTCACT GCTAGTTTCACAGAGACCAGCACAGTTTCACTGGATAATGAAACTACAGTAAAAACCTCAGATATCCTTGACGCACGGAAAACAAATGAG CTCCCCTCAGATAGCAGTTCTTCTTCTGATCTGATCAACACCTCCATAGCTTCTTCAACTATGGATGTCACTAAAACAGCCTCCATCAGT CCCACTAGCATCTCAGGAATGACAGCAAGTTCCTCCCCATCTCTCTTCTCTTCAGATAGACCCCAGGTTCCCACATCTACAACAGAGACA AATACAGCCACCTCTCCATCTGTTTCCAGTAACACCTATTCTCTTGATGGGGGCTCCAATGTGGGTGGCACTCCATCCACTTTACCACCC TTTACAATCACCCACCCTGTCGAGACAAGCTCGGCCCTATTAGCCTGGTCTAGACCAGTAAGAACTTTCAGCACCATGGTCAGCACTGAC ACTGCCTCCGGAGAAAATCCTACCTCTAGCAATTCTGTGGTGACTTCTGTTCCAGCACCAGGTACATGGACCAGTGTAGGCAGTACTACT GACTTACCTGCCATGGGCTTTCTCAAGACAAGTCCTGCAGGAGAGGCACACTCACTTCTAGCATCAACTATTGAACCAGCCACTGCCTTC ACTCCCCATCTCTCAGCAGCAGTGGTCACTGGATCCAGTGCTACATCAGAAGCCAGTCTTCTCACTACGAGTGAAAGCAAAGCCATTCAT TCTTCACCACAGACCCCAACTACACCCACCTCTGGAGCAAACTGGGAAACTTCAGCTACTCCTGAGAGCCTTTTGGTAGTCACTGAGACT TCAGACACAACACTTACCTCAAAGATTTTGGTCACAGATACCATCTTGTTTTCAACTGTGTCCACGCCACCTTCTAAATTTCCAAGTACG GGGACTCTGTCTGGAGCTTCCTTCCCTACTTTACTCCCGGACACTCCAGCCATCCCTCTCACTGCCACTGAGCCAACAAGTTCATTAGCT ACATCCTTTGATTCCACCCCACTGGTGACTATAGCTTCGGATAGTCTTGGCACAGTCCCAGAGACTACCCTGACCATGTCAGAGACCTCA AATGGTGATGCACTGGTTCTTAAGACAGTAAGTAACCCAGATAGGAGCATCCCTGGAATCACTATCCAAGGAGTAACAGAAAGTCCACTC CATCCTTCTTCCACTTCCCCCTCTAAGATTGTTGCTCCACGGAATACAACCTATGAAGGTTCGATCACAGTGGCACTTTCTACTTTGCCT GCGGGAACTACTGGTTCCCTTGTATTCAGTCAGAGTTCTGAAAACTCAGAGACAACGGCTTTGGTAGACTCATCAGCTGGGCTTGAGAGG GCATCTGTGATGCCACTAACCACAGGAAGCCAGGGTATGGCTAGCTCTGGAGGAATCAGAAGTGGGTCCACTCACTCAACTGGAACCAAA ACATTTTCTTCTCTCCCTCTGACCATGAACCCAGGTGAGGTTACAGCCATGTCTGAAATCACCACGAACAGACTGACAGCTACTCAATCA ACAGCACCCAAAGGGATACCTGTGAAGCCCACCAGTGCTGAGTCAGGCCTCCTAACACCTGTCTCTGCCTCCTCAAGCCCATCAAAGGCC TTTGCCTCACTGACTACAGCTCCCCCAACTTGGGGGATCCCACAGTCTACCTTGACATTTGAGTTTTCTGAGGTCCCAAGTTTGGATACT AAGTCCGCTTCTTTACCAACTCCTGGACAGTCCCTGAACACCATTCCAGACTCAGATGCAAGCACAGCATCTTCCTCACTGTCCAAGTCT CCAGAAAAAAACCCAAGGGCAAGGATGATGACTTCCACAAAGGCCATAAGTGCAAGCTCATTTCAATCAACAGGTTTTACTGAAACCCCT GAGGGATCTGCCTCCCCTTCTATGGCAGGGCATGAACCCAGAGTCCCCACTTCAGGAACAGGGGACCCTAGATATGCCTCAGAGAGCATG TCTTATCCAGACCCAAGCAAGGCATCATCAGCTATGACATCGACCTCTCTTGCATCAAAACTCACAACTCTCTTCAGCACAGGTCAAGCA GCAAGGTCTGGTTCTAGTTCCTCTCCCATAAGCCTATCCACTGAGAAAGAAACAAGCTTCCTTTCCCCCACTGCATCCACCTCCAGAAAG ACTTCACTATTTCTTGGGCCTTCCATGGCAAGGCAGCCCAACATATTGGTGCATCTTCAGACTTCAGCTCTGACACTTTCTCCAACATCC ACTCTAAATATGTCCCAGGAGGAGCCTCCTGAGTTAACCTCAAGCCAGACCATTGCAGAAGAAGAGGGAACAACAGCTGAAACACAGACG TTAACCTTCACACCATCTGAGACCCCAACATCCTTGTTACCTGTCTCTTCTCCCACAGAACCCACAGCCAGAAGAAAGAGTTCTCCAGAA ACATGGGCAAGCTCTATTTCAGTTCCTGCCAAGACCTCCTTGGTTGAAACAACTGATGGAACGCTAGTGACCACCATAAAGATGTCAAGC CAGGCAGCACAAGGAAATTCCACGTGGCCTGCCCCAGCAGAGGAGACGGGGAGCAGTCCAGCAGAATATTTAAAAGATGCTTCAAAGAAG ATGAAAAATGGGCTAATGTTTGTAAAACTGGTTAACCCCTGTTCAGGAGAAGGAGCCATTTACTTGTTCAATATGTGTCTACAGCAGCTG TTTGAAGTAAAAGTTTTCAAGGAAAAACACCATTCTTGGTTTATAAATCAATCAGTTCAATCAGGAGGTCTTCTCCATTTTGCCACACCT GTGGATCCTCTATTTCTGCTTCTCCACTACCTCATAAAGGCTGATAAGGAGGGGAAGTTTCAGCCCCTTGATCAAGTTGTGGTGGATAAC GTGTTTCCAAATTGCATCTTGTTGCTGAAACTTCCTGGACTTGAGAAGTTACTTCATCATGTGACAGAGGAAAAAGGTAATCCAGAAATA GACAACAAGAAATATTACAAGTACAGCAAAGAGAAGACATTAAAGTGGCTGGAAAAAAAGGTTAATCAAACTGTGGCAGCATTAAAAACC AATAATGTGAATGTCAGTTCCCGGGTACAGTCAACTGCATTTTTCTCTGGTGACCAAGCTTCCACTGACAAGGAAGAGGATTATATTCGT TATGCCCATGGTCTGATATCTGACTACATCCCTAAAGAATTAAGTGATGACTTATCTAAATACTTAAAGCTTCCAGAACCTTCAGCCTCA TTGCCAAATCCTCCATCAAAGATGGCAGCACAAAGACAGAAAAGGGGCAAGTGATGGTGGTGGCTCCACGCAAGGCTTGGCGGTTTTCCC TGCAACTTCAGACACTCCCAGAGGACTCGGACTTTTTCTTCTGCACTTTTTTGGAAAATCGCCAGGTGCCAAAAGGTGCATTTTAAAGCG CTGACTGTAAATGCTTTATTTCTTTGATTAGTACCACTAGTCTATGTGGGCAGCGGCATTCCTCCCTGGAGCACTCAGCTAGGCGGTTCC GTCCAGGAGCTTGAAAGCATCCCAGCGGTGCACCTGTTCAGTCTGAGGACCTCAAGCTTGGGTCAGGCCAGCATGTTTTAGGTATGGATG TGGTGACTTAAAGTACTTGATTGTCTTGATTTCACCCTGAAAGCTTTGGCAAACCAAGTTTCAACCCTTACTTTAAAAATCTGACACTGC TTTACTCCATATCAATTTGGAAGCTTCTAATTCATAAATATACCTAAACGTTGGCATTTTATCTCTCCAGGAGTTATTAAACATTTCTTC CTTTTT >55996_55996_4_MUC16-RNASEH2B_MUC16_chr19_9080451_ENST00000397910_RNASEH2B_chr13_51501543_ENST00000422660_length(amino acids)=3464AA_BP=3223 MRNFGVSGSSEALQRPPSLRGFFLDLHPEANVDLSMLKPSGLPGSSSPTRSLMTGSRSTKATPEMDSGLTGATLSPKTSTGAIVVTEHTL PFTSPDKTLASPTSSVVGRTTQSLGVMSSALPESTSRGMTHSEQRTSPSLSPQVNGTPSRNYPATSMVSGLSSPRTRTSSTEGNFTKEAS TYTLTVETTSGPVTEKYTVPTETSTTEGDSTETPWDTRYIPVKITSPMKTFADSTASKENAPVSMTPAETTVTDSHTPGRTNPSFGTLYS SFLDLSPKGTPNSRGETSLELILSTTGYPFSSPEPGSAGHSRISTSAPLSSSASVLDNKISETSIFSGQSLTSPLSPGVPEARASTMPNS AIPFSMTLSNAETSAERVRSTISSLGTPSISTKQTAETILTFHAFAETMDIPSTHIAKTLASEWLGSPGTLGGTSTSALTTTSPSTTLVS EETNTHHSTSGKETEGTLNTSMTPLETSAPGEESEMTATLVPTLGFTTLDSKIRSPSQVSSSHPTRELRTTGSTSGRQSSSTAAHGSSDI LRATTSSTSKASSWTSESTAQQFSEPQHTQWVETSPSMKTERPPASTSVAAPITTSVPSVVSGFTTLKTSSTKGIWLEETSADTLIGEST AGPTTHQFAVPTGISMTGGSSTRGSQGTTHLLTRATASSETSADLTLATNGVPVSVSPAVSKTAAGSSPPGGTKPSYTMVSSVIPETSSL QSSAFREGTSLGLTPLNTRHPFSSPEPDSAGHTKISTSIPLLSSASVLEDKVSATSTFSHHKATSSITTGTPEISTKTKPSSAVLSSMTL SNAATSPERVRNATSPLTHPSPSGEETAGSVLTLSTSAETTDSPNIHPTGTLTSESSESPSTLSLPSVSGVKTTFSSSTPSTHLFTSGEE TEETSNPSVSQPETSVSRVRTTLASTSVPTPVFPTMDTWPTRSAQFSSSHLVSELRATSSTSVTNSTGSALPKISHLTGTATMSQTNRDT FNDSAAPQSTTWPETSPRFKTGLPSATTTVSTSATSLSATVMVSKFTSPATSSMEATSIREPSTTILTTETTNGPGSMAVASTNIPIGKG YITEGRLDTSHLPIGTTASSETSMDFTMAKESVSMSVSPSQSMDAAGSSTPGRTSQFVDTFSDDVYHLTSREITIPRDGTSSALTPQMTA THPPSPDPGSARSTWLGILSSSPSSPTPKVTMSSTFSTQRVTTSMIMDTVETSRWNMPNLPSTTSLTPSNIPTSGAIGKSTLVPLDTPSP ATSLEASEGGLPTLSTYPESTNTPSIHLGAHASSESPSTIKLTMASVVKPGSYTPLTFPSIETHIHVSTARMAYSSGSSPEMTAPGETNT GSTWDPTTYITTTDPKDTSSAQVSTPHSVRTLRTTENHPKTESATPAAYSGSPKISSSPNLTSPATKAWTITDTTEHSTQLHYTKLAEKS SGFETQSAPGPVSVVIPTSPTIGSSTLELTSDVPGEPLVLAPSEQTTITLPMATWLSTSLTEEMASTDLDISSPSSPMSTFAIFPPMSTP SHELSKSEADTSAIRNTDSTTLDQHLGIRSLGRTGDLTTVPITPLTTTWTSVIEHSTQAQDTLSATMSPTHVTQSLKDQTSIPASASPSH LTEVYPELGTQGRSSSEATTFWKPSTDTLSREIETGPTNIQSTPPMDNTTTGSSSSGVTLGIAHLPIGTSSPAETSTNMALERRSSTATV SMAGTMGLLVTSAPGRSISQSLGRVSSVLSESTTEGVTDSSKGSSPRLNTQGNTALSSSLEPSYAEGSQMSTSIPLTSSPTTPDVEFIGG STFWTKEVTTVMTSDISKSSARTESSSATLMSTALGSTENTGKEKLRTASMDLPSPTPSMEVTPWISLTLSNAPNTTDSLDLSHGVHTSS AGTLATDRSLNTGVTRASRLENGSDTSSKSLSMGNSTHTSMTYTEKSEVSSSIHPRPETSAPGAETTLTSTPGNRAISLTLPFSSIPVEE VISTGITSGPDINSAPMTHSPITPPTIVWTSTGTIEQSTQPLHAVSSEKVSVQTQSTPYVNSVAVSASPTHENSVSSGSSTSSPYSSASL ESLDSTISRRNAITSWLWDLTTSLPTTTWPSTSLSEALSSGHSGVSNPSSTTTEFPLFSAASTSAAKQRNPETETHGPQNTAASTLNTDA SSVTGLSETPVGASISSEVPLPMAITSRSDVSGLTSESTANPSLGTASSAGTKLTRTISLPTSESLVSFRMNKDPWTVSIPLGSHPTTNT ETSIPVNSAGPPGLSTVASDVIDTPSDGAESIPTVSFSPSPDTEVTTISHFPEKTTHSFRTISSLTHELTSRVTPIPGDWMSSAMSTKPT GASPSITLGERRTITSAAPTTSPIVLTASFTETSTVSLDNETTVKTSDILDARKTNELPSDSSSSSDLINTSIASSTMDVTKTASISPTS ISGMTASSSPSLFSSDRPQVPTSTTETNTATSPSVSSNTYSLDGGSNVGGTPSTLPPFTITHPVETSSALLAWSRPVRTFSTMVSTDTAS GENPTSSNSVVTSVPAPGTWTSVGSTTDLPAMGFLKTSPAGEAHSLLASTIEPATAFTPHLSAAVVTGSSATSEASLLTTSESKAIHSSP QTPTTPTSGANWETSATPESLLVVTETSDTTLTSKILVTDTILFSTVSTPPSKFPSTGTLSGASFPTLLPDTPAIPLTATEPTSSLATSF DSTPLVTIASDSLGTVPETTLTMSETSNGDALVLKTVSNPDRSIPGITIQGVTESPLHPSSTSPSKIVAPRNTTYEGSITVALSTLPAGT TGSLVFSQSSENSETTALVDSSAGLERASVMPLTTGSQGMASSGGIRSGSTHSTGTKTFSSLPLTMNPGEVTAMSEITTNRLTATQSTAP KGIPVKPTSAESGLLTPVSASSSPSKAFASLTTAPPTWGIPQSTLTFEFSEVPSLDTKSASLPTPGQSLNTIPDSDASTASSSLSKSPEK NPRARMMTSTKAISASSFQSTGFTETPEGSASPSMAGHEPRVPTSGTGDPRYASESMSYPDPSKASSAMTSTSLASKLTTLFSTGQAARS GSSSSPISLSTEKETSFLSPTASTSRKTSLFLGPSMARQPNILVHLQTSALTLSPTSTLNMSQEEPPELTSSQTIAEEEGTTAETQTLTF TPSETPTSLLPVSSPTEPTARRKSSPETWASSISVPAKTSLVETTDGTLVTTIKMSSQAAQGNSTWPAPAEETGSSPAEYLKDASKKMKN GLMFVKLVNPCSGEGAIYLFNMCLQQLFEVKVFKEKHHSWFINQSVQSGGLLHFATPVDPLFLLLHYLIKADKEGKFQPLDQVVVDNVFP NCILLLKLPGLEKLLHHVTEEKGNPEIDNKKYYKYSKEKTLKWLEKKVNQTVAALKTNNVNVSSRVQSTAFFSGDQASTDKEEDYIRYAH GLISDYIPKELSDDLSKYLKLPEPSASLPNPPSKMAAQRQKRGK -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for MUC16-RNASEH2B |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for MUC16-RNASEH2B |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for MUC16-RNASEH2B |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | MUC16 | C0033687 | Proteinuria | 1 | CTD_human |
| Hgene | MUC16 | C0919267 | ovarian neoplasm | 1 | CTD_human |
| Hgene | MUC16 | C1140680 | Malignant neoplasm of ovary | 1 | CTD_human |
| Tgene | C3489724 | Aicardi-Goutieres Syndrome 2 | 8 | CTD_human;GENOMICS_ENGLAND;UNIPROT | |
| Tgene | C0013421 | Dystonia | 1 | GENOMICS_ENGLAND | |
| Tgene | C0037771 | Paraparesis, Spastic | 1 | GENOMICS_ENGLAND | |
| Tgene | C0393591 | AICARDI-GOUTIERES SYNDROME | 1 | CTD_human;GENOMICS_ENGLAND | |
| Tgene | C3714756 | Intellectual Disability | 1 | GENOMICS_ENGLAND |
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