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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:TJP2-TMEM38B (FusionGDB2 ID:HG9414TG55151)

Fusion Gene Summary for TJP2-TMEM38B

check button Fusion gene summary
Fusion gene informationFusion gene name: TJP2-TMEM38B
Fusion gene ID: hg9414tg55151
HgeneTgene
Gene symbol

TJP2

TMEM38B

Gene ID

9414

55151

Gene nametight junction protein 2transmembrane protein 38B
SynonymsC9DUPq21.11|DFNA51|DUP9q21.11|PFIC4|X104|ZO2C9orf87|D4Ertd89e|OI14|TRIC-B|TRICB|bA219P18.1
Cytomap('TJP2')('TMEM38B')

9q21.11

9q31.2

Type of geneprotein-codingprotein-coding
Descriptiontight junction protein ZO-2Friedreich ataxia region gene X104 (tight junction protein ZO-2)zona occludens 2zonula occludens protein 2trimeric intracellular cation channel type B
Modification date2020032020200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000265384, ENST00000348208, 
ENST00000377245, ENST00000453658, 
ENST00000535702, ENST00000539225, 
ENST00000377259, ENST00000498204, 
Fusion gene scores* DoF score13 X 14 X 8=14567 X 5 X 6=210
# samples 157
** MAII scorelog2(15/1456*10)=-3.27897594970282
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/210*10)=-1.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TJP2 [Title/Abstract] AND TMEM38B [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointTJP2(71845148)-TMEM38B(108536146), # samples:3
Anticipated loss of major functional domain due to fusion event.TJP2-TMEM38B seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
TJP2-TMEM38B seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
TJP2-TMEM38B seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
TJP2-TMEM38B seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneTJP2

GO:0034109

homotypic cell-cell adhesion

21679692


check buttonFusion gene breakpoints across TJP2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across TMEM38B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A2-A0EW-01ATJP2chr9

71845148

-TMEM38Bchr9

108536146

+
ChimerDB4BRCATCGA-A2-A0EW-01ATJP2chr9

71845148

+TMEM38Bchr9

108536146

+


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Fusion Gene ORF analysis for TJP2-TMEM38B

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000265384ENST00000374688TJP2chr9

71845148

+TMEM38Bchr9

108536146

+
In-frameENST00000265384ENST00000374692TJP2chr9

71845148

+TMEM38Bchr9

108536146

+
In-frameENST00000348208ENST00000374688TJP2chr9

71845148

+TMEM38Bchr9

108536146

+
In-frameENST00000348208ENST00000374692TJP2chr9

71845148

+TMEM38Bchr9

108536146

+
In-frameENST00000377245ENST00000374688TJP2chr9

71845148

+TMEM38Bchr9

108536146

+
In-frameENST00000377245ENST00000374692TJP2chr9

71845148

+TMEM38Bchr9

108536146

+
In-frameENST00000453658ENST00000374688TJP2chr9

71845148

+TMEM38Bchr9

108536146

+
In-frameENST00000453658ENST00000374692TJP2chr9

71845148

+TMEM38Bchr9

108536146

+
In-frameENST00000535702ENST00000374688TJP2chr9

71845148

+TMEM38Bchr9

108536146

+
In-frameENST00000535702ENST00000374692TJP2chr9

71845148

+TMEM38Bchr9

108536146

+
In-frameENST00000539225ENST00000374688TJP2chr9

71845148

+TMEM38Bchr9

108536146

+
In-frameENST00000539225ENST00000374692TJP2chr9

71845148

+TMEM38Bchr9

108536146

+
intron-3CDSENST00000377259ENST00000374688TJP2chr9

71845148

+TMEM38Bchr9

108536146

+
intron-3CDSENST00000377259ENST00000374692TJP2chr9

71845148

+TMEM38Bchr9

108536146

+
intron-3CDSENST00000498204ENST00000374688TJP2chr9

71845148

+TMEM38Bchr9

108536146

+
intron-3CDSENST00000498204ENST00000374692TJP2chr9

71845148

+TMEM38Bchr9

108536146

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000453658TJP2chr971845148+ENST00000374692TMEM38Bchr9108536146+4538179022005667
ENST00000453658TJP2chr971845148+ENST00000374688TMEM38Bchr9108536146+4538179022005667
ENST00000377245TJP2chr971845148+ENST00000374692TMEM38Bchr9108536146+462718791782094638
ENST00000377245TJP2chr971845148+ENST00000374688TMEM38Bchr9108536146+462718791782094638
ENST00000348208TJP2chr971845148+ENST00000374692TMEM38Bchr9108536146+45151767661982638
ENST00000348208TJP2chr971845148+ENST00000374688TMEM38Bchr9108536146+45151767661982638
ENST00000265384TJP2chr971845148+ENST00000374692TMEM38Bchr9108536146+44981750491965638
ENST00000265384TJP2chr971845148+ENST00000374688TMEM38Bchr9108536146+44981750491965638
ENST00000535702TJP2chr971845148+ENST00000374692TMEM38Bchr9108536146+458218341272049640
ENST00000535702TJP2chr971845148+ENST00000374688TMEM38Bchr9108536146+458218341272049640
ENST00000539225TJP2chr971845148+ENST00000374692TMEM38Bchr9108536146+4512176401979659
ENST00000539225TJP2chr971845148+ENST00000374688TMEM38Bchr9108536146+4512176401979659

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000453658ENST00000374692TJP2chr971845148+TMEM38Bchr9108536146+0.0003725060.9996275
ENST00000453658ENST00000374688TJP2chr971845148+TMEM38Bchr9108536146+0.0003725060.9996275
ENST00000377245ENST00000374692TJP2chr971845148+TMEM38Bchr9108536146+0.0006705770.99932945
ENST00000377245ENST00000374688TJP2chr971845148+TMEM38Bchr9108536146+0.0006705770.99932945
ENST00000348208ENST00000374692TJP2chr971845148+TMEM38Bchr9108536146+0.000659020.99934095
ENST00000348208ENST00000374688TJP2chr971845148+TMEM38Bchr9108536146+0.000659020.99934095
ENST00000265384ENST00000374692TJP2chr971845148+TMEM38Bchr9108536146+0.0006590310.99934095
ENST00000265384ENST00000374688TJP2chr971845148+TMEM38Bchr9108536146+0.0006590310.99934095
ENST00000535702ENST00000374692TJP2chr971845148+TMEM38Bchr9108536146+0.0002362510.9997638
ENST00000535702ENST00000374688TJP2chr971845148+TMEM38Bchr9108536146+0.0002362510.9997638
ENST00000539225ENST00000374692TJP2chr971845148+TMEM38Bchr9108536146+0.0009744930.99902546
ENST00000539225ENST00000374688TJP2chr971845148+TMEM38Bchr9108536146+0.0009744930.99902546

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Fusion Genomic Features for TJP2-TMEM38B


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
TJP2chr971845148+TMEM38Bchr9108536145+9.21E-060.9999908
TJP2chr971845148+TMEM38Bchr9108536145+9.21E-060.9999908

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for TJP2-TMEM38B


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:71845148/chr9:108536146)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTJP2chr9:71845148chr9:108536146ENST00000265384+1119307_385557994.0DomainPDZ 2
HgeneTJP2chr9:71845148chr9:108536146ENST00000265384+111933_120557994.0DomainPDZ 1
HgeneTJP2chr9:71845148chr9:108536146ENST00000348208+1121307_3855571044.0DomainPDZ 2
HgeneTJP2chr9:71845148chr9:108536146ENST00000348208+112133_1205571044.0DomainPDZ 1
HgeneTJP2chr9:71845148chr9:108536146ENST00000377245+1123307_3855571191.0DomainPDZ 2
HgeneTJP2chr9:71845148chr9:108536146ENST00000377245+112333_1205571191.0DomainPDZ 1
HgeneTJP2chr9:71845148chr9:108536146ENST00000453658+1222307_3855341021.0DomainPDZ 2
HgeneTJP2chr9:71845148chr9:108536146ENST00000453658+122233_1205341021.0DomainPDZ 1
HgeneTJP2chr9:71845148chr9:108536146ENST00000535702+1122307_3855611158.0DomainPDZ 2
HgeneTJP2chr9:71845148chr9:108536146ENST00000535702+112233_1205611158.0DomainPDZ 1
HgeneTJP2chr9:71845148chr9:108536146ENST00000539225+1123307_3855881222.0DomainPDZ 2
HgeneTJP2chr9:71845148chr9:108536146ENST00000539225+112333_1205881222.0DomainPDZ 1
HgeneTJP2chr9:71845148chr9:108536146ENST00000539225+1123509_5905881222.0DomainPDZ 3
TgeneTMEM38Bchr9:71845148chr9:108536146ENST0000037469246228_291220292.0Topological domainCytoplasmic

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTJP2chr9:71845148chr9:108536146ENST00000265384+11191162_1165557994.0Compositional biasNote=Poly-Glu
HgeneTJP2chr9:71845148chr9:108536146ENST00000348208+11211162_11655571044.0Compositional biasNote=Poly-Glu
HgeneTJP2chr9:71845148chr9:108536146ENST00000377245+11231162_11655571191.0Compositional biasNote=Poly-Glu
HgeneTJP2chr9:71845148chr9:108536146ENST00000453658+12221162_11655341021.0Compositional biasNote=Poly-Glu
HgeneTJP2chr9:71845148chr9:108536146ENST00000535702+11221162_11655611158.0Compositional biasNote=Poly-Glu
HgeneTJP2chr9:71845148chr9:108536146ENST00000539225+11231162_11655881222.0Compositional biasNote=Poly-Glu
HgeneTJP2chr9:71845148chr9:108536146ENST00000265384+1119509_590557994.0DomainPDZ 3
HgeneTJP2chr9:71845148chr9:108536146ENST00000265384+1119604_669557994.0DomainSH3
HgeneTJP2chr9:71845148chr9:108536146ENST00000265384+1119678_876557994.0DomainGuanylate kinase-like
HgeneTJP2chr9:71845148chr9:108536146ENST00000348208+1121509_5905571044.0DomainPDZ 3
HgeneTJP2chr9:71845148chr9:108536146ENST00000348208+1121604_6695571044.0DomainSH3
HgeneTJP2chr9:71845148chr9:108536146ENST00000348208+1121678_8765571044.0DomainGuanylate kinase-like
HgeneTJP2chr9:71845148chr9:108536146ENST00000377245+1123509_5905571191.0DomainPDZ 3
HgeneTJP2chr9:71845148chr9:108536146ENST00000377245+1123604_6695571191.0DomainSH3
HgeneTJP2chr9:71845148chr9:108536146ENST00000377245+1123678_8765571191.0DomainGuanylate kinase-like
HgeneTJP2chr9:71845148chr9:108536146ENST00000453658+1222509_5905341021.0DomainPDZ 3
HgeneTJP2chr9:71845148chr9:108536146ENST00000453658+1222604_6695341021.0DomainSH3
HgeneTJP2chr9:71845148chr9:108536146ENST00000453658+1222678_8765341021.0DomainGuanylate kinase-like
HgeneTJP2chr9:71845148chr9:108536146ENST00000535702+1122509_5905611158.0DomainPDZ 3
HgeneTJP2chr9:71845148chr9:108536146ENST00000535702+1122604_6695611158.0DomainSH3
HgeneTJP2chr9:71845148chr9:108536146ENST00000535702+1122678_8765611158.0DomainGuanylate kinase-like
HgeneTJP2chr9:71845148chr9:108536146ENST00000539225+1123604_6695881222.0DomainSH3
HgeneTJP2chr9:71845148chr9:108536146ENST00000539225+1123678_8765881222.0DomainGuanylate kinase-like
TgeneTMEM38Bchr9:71845148chr9:108536146ENST0000037469246100_104220292.0Topological domainCytoplasmic
TgeneTMEM38Bchr9:71845148chr9:108536146ENST0000037469246122_139220292.0Topological domainLumenal
TgeneTMEM38Bchr9:71845148chr9:108536146ENST0000037469246157_179220292.0Topological domainCytoplasmic
TgeneTMEM38Bchr9:71845148chr9:108536146ENST0000037469246196_207220292.0Topological domainLumenal
TgeneTMEM38Bchr9:71845148chr9:108536146ENST00000374692461_19220292.0Topological domainLumenal
TgeneTMEM38Bchr9:71845148chr9:108536146ENST000003746924634_50220292.0Topological domainCytoplasmic
TgeneTMEM38Bchr9:71845148chr9:108536146ENST000003746924671_82220292.0Topological domainLumenal
TgeneTMEM38Bchr9:71845148chr9:108536146ENST0000037469246105_121220292.0TransmembraneHelical%3BName%3D4
TgeneTMEM38Bchr9:71845148chr9:108536146ENST0000037469246140_156220292.0TransmembraneHelical%3BName%3D5
TgeneTMEM38Bchr9:71845148chr9:108536146ENST0000037469246180_195220292.0TransmembraneHelical%3BName%3D6
TgeneTMEM38Bchr9:71845148chr9:108536146ENST0000037469246208_227220292.0TransmembraneHelical%3BName%3D7
TgeneTMEM38Bchr9:71845148chr9:108536146ENST000003746924620_33220292.0TransmembraneHelical%3BName%3D1
TgeneTMEM38Bchr9:71845148chr9:108536146ENST000003746924651_70220292.0TransmembraneHelical%3BName%3D2
TgeneTMEM38Bchr9:71845148chr9:108536146ENST000003746924683_99220292.0TransmembraneHelical%3BName%3D3


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Fusion Gene Sequence for TJP2-TMEM38B


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>91068_91068_1_TJP2-TMEM38B_TJP2_chr9_71845148_ENST00000265384_TMEM38B_chr9_108536146_ENST00000374688_length(transcript)=4498nt_BP=1750nt
TGCCCAGGAGGAGTAGGAGCAGGAGCAGAAGCAGAAGCGGGGTCCGGAGCTGCGCGCCTACGCGGGACCTGTGTCCGAAATGCCGGTGCG
AGGAGACCGCGGGTTTCCACCCCGGCGGGAGCTGTCAGGTTGGCTCCGCGCCCCAGGCATGGAAGAGCTGATATGGGAACAGTACACTGT
GACCCTACAAAAGGATTCCAAAAGAGGATTTGGAATTGCAGTGTCCGGAGGCAGAGACAACCCCCACTTTGAAAATGGAGAAACGTCAAT
TGTCATTTCTGATGTGCTCCCGGGTGGGCCTGCTGATGGGCTGCTCCAAGAAAATGACAGAGTGGTCATGGTCAATGGCACCCCCATGGA
GGATGTGCTTCATTCGTTTGCAGTTCAGCAGCTCAGAAAAAGTGGGAAGGTCGCTGCTATTGTGGTCAAGAGGCCCCGGAAGGTCCAGGT
GGCCGCACTTCAGGCCAGCCCTCCCCTGGATCAGGATGACCGGGCTTTTGAGGTGATGGACGAGTTTGATGGCAGAAGTTTCCGGAGTGG
CTACAGCGAGAGGAGCCGGCTGAACAGCCATGGGGGGCGCAGCCGCAGCTGGGAGGACAGCCCGGAAAGGGGGCGTCCCCATGAGCGGGC
CCGGAGCCGGGAGCGGGACCTCAGCCGGGACCGGAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCAAGACCATGCGCGCACCCGAGA
CCGCAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCACGACTTTGGGCCATCCCGGGACCGGGACCGTGACCGCAGCCGCGGCCGGAG
CATTGACCAGGACTACGAGCGAGCCTATCACCGGGCCTACGACCCAGACTACGAGCGGGCCTACAGCCCGGAGTACAGGCGCGGGGCCCG
CCACGATGCCCGCTCTCGGGGACCCCGAAGCCGCAGCCGCGAGCACCCGCACTCACGGAGCCCCAGCCCCGAGCCTAGGGGGCGGCCGGG
GCCCATCGGGGTCCTCCTGATGAAAAGCAGAGCGAACGAAGAGTATGGTCTCCGGCTTGGGAGTCAGATCTTCGTAAAGGAAATGACCCG
AACGGGTCTGGCAACTAAAGATGGCAACCTTCACGAAGGAGACATAATTCTCAAGATCAATGGGACTGTAACTGAGAACATGTCTTTAAC
GGATGCTCGAAAATTGATAGAAAAGTCAAGAGGAAAACTACAGCTAGTGGTGTTGAGAGACAGCCAGCAGACCCTCATCAACATCCCGTC
ATTAAATGACAGTGACTCAGAAATAGAAGATATTTCAGAAATAGAGTCAAACCGATCATTTTCTCCAGAGGAGAGACGTCATCAGTATTC
TGATTATGATTATCATTCCTCAAGTGAGAAGCTGAAGGAAAGGCCAAGTTCCAGAGAGGACACGCCGAGCAGATTGTCCAGGATGGGTGC
GACACCCACTCCCTTTAAGTCCACAGGGGATATTGCAGGCACAGTTGTCCCAGAGACCAACAAGGAACCCAGATACCAAGAGGACCCCCC
AGCTCCTCAACCAAAAGCAGCCCCGAGAACTTTTCTTCGTCCTAGTCCTGAAGATGAAGCAATATATGGCCCTAATACCAAAATGGTAAG
GTTCAAGAAGGGAGACAGCGTGGGCCTCCGGTTGGCTGGTGGCAATGATGTCGGGATATTTGTTGCTGGCATTCAAGAAGGGACCTCGGC
GGAGCAGGAGGGCCTTCAAGAAGGAGACCAGATTCTGAAGATAACCATGATGACTACACAGACTTCTACTATGACATTTGCTCCTTTTGA
GGATACATTGAGTTGGATGCTATTTGGCTGGCAGCAGCCGTTTTCATCATGTGAGAAGAAAAGTGAAGCAAAGTCACCTTCCAATGGCGT
TGGGTCATTGGCCTCAAAGCCGGTAGATGTTGCCTCAGATAATGTTAAAAAGAAACATACTAAGAAGAATGAATAAATTTACGTGATGAG
CTCTACAAGGCCAAAAATTTTTTTTCTTATCTACCTGTTATATTGTGCTAATTTTTCTATGTATGTGATGTGAAATGAAGACTATATATA
TGGAATGGAGGTGACAGAAAGAAAGAAATTCTTTGTTTGAGGGAGACTTCCCCTTTCTGGATTGTATTTGTAGAGTGTTACGAGTGTATC
ATGTGATTATGCTTTACCGGTATAAGAGATTCTGTTGTGATTATTTGAATAGTTTTATATTAATAAAAGAAGACAAAATTTTTTAAATGT
TAGAAAAAGCAGATCTGTCATTGCAAAGTAACAAAAATTTTAAGCTTTTAAAAATGTAGATTTTTCATATTTTTAAAATTTGAATCTATT
TGAGCTTTAGTTCAGCAGAATTAAATTTTTACTTGACATTATCATTAAAATTGCTAGGTATGGAGAACAATTCCTATTTTATTTTGAACA
CTGAGAAGAGTAAACTTTTCCTAAAACACTTTATATTATAAATGAAAATAAATTGCTAGTTTATATTTTAGATATAAACATCATATTTTT
TATTAATACCTACATCAAATGGAAAATATCTGAAATTTTTTTTCCATAGCAGGTATTTTCTACTAGAAGTAGTTTTACTACTTTTCATTT
AGAACAGAGTATGAGTCTTAATCTGAAGTCTTTTTCATGCCCTTGTTTTAAAAAAACTACTTTTTTTGGCCTCAAAAAAATCAAGGGTGT
AATTTTTAATAAATTGTTAATCCTATGTTTTGTAATTTTCATTTTAGGAGCTTGACTTATTTTTTTCTCTCTCATAAAAACACATTTGTT
TTAATTGTAGGAGAAATTTTCTCAGCATTTTGCATGTTCTTTCTAATCTTTGTTGGTCTGAATATATTGGTAGTAATTACTGTAATTATT
CAACAAAAAGCATATCCGTTCAAAAATTTTTCCACTATGTCTTTTTTCTAGTGGCTACTGTTTTAGTTTTCTAGTTGAATATCTCTGACA
AGCTTTCGTATGGTTTTGTTATATTTTCATCTACATGTAATGTGTTATTAATTTTATTAAATGAAAACTAATCACCTTCATGTGGAAATG
CTCTGAGAATTGTCCTTAGGCATTTGGTAGTAACCAGCTAACCAAGAAGAAACAGAGAAACCAGAACTTCATATGGCAGTCCATTTAGAT
GAAGAATGATGATATAAAATCTGGTTCCTTCTTAGCAAAATAAAAAACAAACAAGAAAAGATACTAAATGATGTTAATTTTCTTACTTTA
TGATTTAGAAGTCCAGTTATAATATTAAAACTCTGTGACATAGTTTCTTTTACCAAAACCATGAACCTACTCCCCGTATCAGGTATTTTC
GATGGTTTAGAAGTACTCAAGTCACATCACATTCAAGTTAGAAGTTTTTTTTTTGTTGTTGTTATTTTAAATTTTTAACAAATATAAACA
CCAGCAGATACTATTACTTGCTTAAAAAATTGGGAGGGGGCACTTTTCATAGTCTTGGAATGCTAAGAAGTTTTATTTTTAATATTGTGA
CAGAAAGCTTTAAGTATTTAAGAGCTCTGTATTATATTTGATACTCTTACAGTTAAAAACTTTTCAAAATTAATACATTGTTAATTATTG
ACCAGTTTTGAAGTTTGGGTTTAACTGTAGTTGAAATGGAAGGACTCTTGTTTTACACTTGTATTAAAGATAAATTTATTAAAATAAGTT
ATTTAGCACCAATGGAGTATTACATTATTTTTATGTTTTATATTTTTCTTGAGGTAGAGTTTCAGAACTCATCTAGTATTTTGACTAATA
TAGTATATATTCAGTGATTACTGTTCAAATGGGACATTGGTAGAAACTTTATTAATCTATGCAAGTATCCTATAACCCTCAATTCAAGGC
TCTTTTGTAAAAAATGTACTGGAGAACATGGCTTAGGCCTGAAACCCATCCTGAATCTATTCAGGTCACCTGTAGAGTCTTGACTTGGAT
TTGCAAAGCAGATTGTTAGACTCCTTACCCAATGTGAAGTGTGAATAAGGCCTATAGGCCTGCCTCACACAGCTAATCAGAGGTGGCACT
GAGAAAGTCAAGTCCTAATAGGTCTCCTTAAAAAAAAAAAGGAGACAAAAAGCTGGCAAGAACATGAGCCAGCTTCCCTCAGTGCTGTCA
CTCTCAAGTAAAACATGGCCAAATGAATATCAAACTGGTTTATCAGATTAGTCACTCTTCCTTACTGAGGGAGTATCAAGTAAGGGCTGG
AGAGAGACCAGATATGTGGAGTTGTTGGCTTTCAGTGGAAATGGTAGCCTCCCTGTGGGTAGAGACCAAAAGGTAGAGAGATGACAGAAG
GGAGACTCTGATTAGTGTATTTTTTTTTTGTCTATTCCTTAAAGCCCAGACACCTTTCCATTAAAATCTACTTCAAATCACAAGTTGATT
ACAATTGAGTGGAACATCCCATGTTGTAAATGGAATAATGTGTTCAGAATGCTCTTTCTTTCCCCCAATAAAGCCCTTTATAGTGTTT

>91068_91068_1_TJP2-TMEM38B_TJP2_chr9_71845148_ENST00000265384_TMEM38B_chr9_108536146_ENST00000374688_length(amino acids)=638AA_BP=567
MRAYAGPVSEMPVRGDRGFPPRRELSGWLRAPGMEELIWEQYTVTLQKDSKRGFGIAVSGGRDNPHFENGETSIVISDVLPGGPADGLLQ
ENDRVVMVNGTPMEDVLHSFAVQQLRKSGKVAAIVVKRPRKVQVAALQASPPLDQDDRAFEVMDEFDGRSFRSGYSERSRLNSHGGRSRS
WEDSPERGRPHERARSRERDLSRDRSRGRSLERGLDQDHARTRDRSRGRSLERGLDHDFGPSRDRDRDRSRGRSIDQDYERAYHRAYDPD
YERAYSPEYRRGARHDARSRGPRSRSREHPHSRSPSPEPRGRPGPIGVLLMKSRANEEYGLRLGSQIFVKEMTRTGLATKDGNLHEGDII
LKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSQQTLINIPSLNDSDSEIEDISEIESNRSFSPEERRHQYSDYDYHSSSEKLKERPS
SREDTPSRLSRMGATPTPFKSTGDIAGTVVPETNKEPRYQEDPPAPQPKAAPRTFLRPSPEDEAIYGPNTKMVRFKKGDSVGLRLAGGND
VGIFVAGIQEGTSAEQEGLQEGDQILKITMMTTQTSTMTFAPFEDTLSWMLFGWQQPFSSCEKKSEAKSPSNGVGSLASKPVDVASDNVK
KKHTKKNE

--------------------------------------------------------------
>91068_91068_2_TJP2-TMEM38B_TJP2_chr9_71845148_ENST00000265384_TMEM38B_chr9_108536146_ENST00000374692_length(transcript)=4498nt_BP=1750nt
TGCCCAGGAGGAGTAGGAGCAGGAGCAGAAGCAGAAGCGGGGTCCGGAGCTGCGCGCCTACGCGGGACCTGTGTCCGAAATGCCGGTGCG
AGGAGACCGCGGGTTTCCACCCCGGCGGGAGCTGTCAGGTTGGCTCCGCGCCCCAGGCATGGAAGAGCTGATATGGGAACAGTACACTGT
GACCCTACAAAAGGATTCCAAAAGAGGATTTGGAATTGCAGTGTCCGGAGGCAGAGACAACCCCCACTTTGAAAATGGAGAAACGTCAAT
TGTCATTTCTGATGTGCTCCCGGGTGGGCCTGCTGATGGGCTGCTCCAAGAAAATGACAGAGTGGTCATGGTCAATGGCACCCCCATGGA
GGATGTGCTTCATTCGTTTGCAGTTCAGCAGCTCAGAAAAAGTGGGAAGGTCGCTGCTATTGTGGTCAAGAGGCCCCGGAAGGTCCAGGT
GGCCGCACTTCAGGCCAGCCCTCCCCTGGATCAGGATGACCGGGCTTTTGAGGTGATGGACGAGTTTGATGGCAGAAGTTTCCGGAGTGG
CTACAGCGAGAGGAGCCGGCTGAACAGCCATGGGGGGCGCAGCCGCAGCTGGGAGGACAGCCCGGAAAGGGGGCGTCCCCATGAGCGGGC
CCGGAGCCGGGAGCGGGACCTCAGCCGGGACCGGAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCAAGACCATGCGCGCACCCGAGA
CCGCAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCACGACTTTGGGCCATCCCGGGACCGGGACCGTGACCGCAGCCGCGGCCGGAG
CATTGACCAGGACTACGAGCGAGCCTATCACCGGGCCTACGACCCAGACTACGAGCGGGCCTACAGCCCGGAGTACAGGCGCGGGGCCCG
CCACGATGCCCGCTCTCGGGGACCCCGAAGCCGCAGCCGCGAGCACCCGCACTCACGGAGCCCCAGCCCCGAGCCTAGGGGGCGGCCGGG
GCCCATCGGGGTCCTCCTGATGAAAAGCAGAGCGAACGAAGAGTATGGTCTCCGGCTTGGGAGTCAGATCTTCGTAAAGGAAATGACCCG
AACGGGTCTGGCAACTAAAGATGGCAACCTTCACGAAGGAGACATAATTCTCAAGATCAATGGGACTGTAACTGAGAACATGTCTTTAAC
GGATGCTCGAAAATTGATAGAAAAGTCAAGAGGAAAACTACAGCTAGTGGTGTTGAGAGACAGCCAGCAGACCCTCATCAACATCCCGTC
ATTAAATGACAGTGACTCAGAAATAGAAGATATTTCAGAAATAGAGTCAAACCGATCATTTTCTCCAGAGGAGAGACGTCATCAGTATTC
TGATTATGATTATCATTCCTCAAGTGAGAAGCTGAAGGAAAGGCCAAGTTCCAGAGAGGACACGCCGAGCAGATTGTCCAGGATGGGTGC
GACACCCACTCCCTTTAAGTCCACAGGGGATATTGCAGGCACAGTTGTCCCAGAGACCAACAAGGAACCCAGATACCAAGAGGACCCCCC
AGCTCCTCAACCAAAAGCAGCCCCGAGAACTTTTCTTCGTCCTAGTCCTGAAGATGAAGCAATATATGGCCCTAATACCAAAATGGTAAG
GTTCAAGAAGGGAGACAGCGTGGGCCTCCGGTTGGCTGGTGGCAATGATGTCGGGATATTTGTTGCTGGCATTCAAGAAGGGACCTCGGC
GGAGCAGGAGGGCCTTCAAGAAGGAGACCAGATTCTGAAGATAACCATGATGACTACACAGACTTCTACTATGACATTTGCTCCTTTTGA
GGATACATTGAGTTGGATGCTATTTGGCTGGCAGCAGCCGTTTTCATCATGTGAGAAGAAAAGTGAAGCAAAGTCACCTTCCAATGGCGT
TGGGTCATTGGCCTCAAAGCCGGTAGATGTTGCCTCAGATAATGTTAAAAAGAAACATACTAAGAAGAATGAATAAATTTACGTGATGAG
CTCTACAAGGCCAAAAATTTTTTTTCTTATCTACCTGTTATATTGTGCTAATTTTTCTATGTATGTGATGTGAAATGAAGACTATATATA
TGGAATGGAGGTGACAGAAAGAAAGAAATTCTTTGTTTGAGGGAGACTTCCCCTTTCTGGATTGTATTTGTAGAGTGTTACGAGTGTATC
ATGTGATTATGCTTTACCGGTATAAGAGATTCTGTTGTGATTATTTGAATAGTTTTATATTAATAAAAGAAGACAAAATTTTTTAAATGT
TAGAAAAAGCAGATCTGTCATTGCAAAGTAACAAAAATTTTAAGCTTTTAAAAATGTAGATTTTTCATATTTTTAAAATTTGAATCTATT
TGAGCTTTAGTTCAGCAGAATTAAATTTTTACTTGACATTATCATTAAAATTGCTAGGTATGGAGAACAATTCCTATTTTATTTTGAACA
CTGAGAAGAGTAAACTTTTCCTAAAACACTTTATATTATAAATGAAAATAAATTGCTAGTTTATATTTTAGATATAAACATCATATTTTT
TATTAATACCTACATCAAATGGAAAATATCTGAAATTTTTTTTCCATAGCAGGTATTTTCTACTAGAAGTAGTTTTACTACTTTTCATTT
AGAACAGAGTATGAGTCTTAATCTGAAGTCTTTTTCATGCCCTTGTTTTAAAAAAACTACTTTTTTTGGCCTCAAAAAAATCAAGGGTGT
AATTTTTAATAAATTGTTAATCCTATGTTTTGTAATTTTCATTTTAGGAGCTTGACTTATTTTTTTCTCTCTCATAAAAACACATTTGTT
TTAATTGTAGGAGAAATTTTCTCAGCATTTTGCATGTTCTTTCTAATCTTTGTTGGTCTGAATATATTGGTAGTAATTACTGTAATTATT
CAACAAAAAGCATATCCGTTCAAAAATTTTTCCACTATGTCTTTTTTCTAGTGGCTACTGTTTTAGTTTTCTAGTTGAATATCTCTGACA
AGCTTTCGTATGGTTTTGTTATATTTTCATCTACATGTAATGTGTTATTAATTTTATTAAATGAAAACTAATCACCTTCATGTGGAAATG
CTCTGAGAATTGTCCTTAGGCATTTGGTAGTAACCAGCTAACCAAGAAGAAACAGAGAAACCAGAACTTCATATGGCAGTCCATTTAGAT
GAAGAATGATGATATAAAATCTGGTTCCTTCTTAGCAAAATAAAAAACAAACAAGAAAAGATACTAAATGATGTTAATTTTCTTACTTTA
TGATTTAGAAGTCCAGTTATAATATTAAAACTCTGTGACATAGTTTCTTTTACCAAAACCATGAACCTACTCCCCGTATCAGGTATTTTC
GATGGTTTAGAAGTACTCAAGTCACATCACATTCAAGTTAGAAGTTTTTTTTTTGTTGTTGTTATTTTAAATTTTTAACAAATATAAACA
CCAGCAGATACTATTACTTGCTTAAAAAATTGGGAGGGGGCACTTTTCATAGTCTTGGAATGCTAAGAAGTTTTATTTTTAATATTGTGA
CAGAAAGCTTTAAGTATTTAAGAGCTCTGTATTATATTTGATACTCTTACAGTTAAAAACTTTTCAAAATTAATACATTGTTAATTATTG
ACCAGTTTTGAAGTTTGGGTTTAACTGTAGTTGAAATGGAAGGACTCTTGTTTTACACTTGTATTAAAGATAAATTTATTAAAATAAGTT
ATTTAGCACCAATGGAGTATTACATTATTTTTATGTTTTATATTTTTCTTGAGGTAGAGTTTCAGAACTCATCTAGTATTTTGACTAATA
TAGTATATATTCAGTGATTACTGTTCAAATGGGACATTGGTAGAAACTTTATTAATCTATGCAAGTATCCTATAACCCTCAATTCAAGGC
TCTTTTGTAAAAAATGTACTGGAGAACATGGCTTAGGCCTGAAACCCATCCTGAATCTATTCAGGTCACCTGTAGAGTCTTGACTTGGAT
TTGCAAAGCAGATTGTTAGACTCCTTACCCAATGTGAAGTGTGAATAAGGCCTATAGGCCTGCCTCACACAGCTAATCAGAGGTGGCACT
GAGAAAGTCAAGTCCTAATAGGTCTCCTTAAAAAAAAAAAGGAGACAAAAAGCTGGCAAGAACATGAGCCAGCTTCCCTCAGTGCTGTCA
CTCTCAAGTAAAACATGGCCAAATGAATATCAAACTGGTTTATCAGATTAGTCACTCTTCCTTACTGAGGGAGTATCAAGTAAGGGCTGG
AGAGAGACCAGATATGTGGAGTTGTTGGCTTTCAGTGGAAATGGTAGCCTCCCTGTGGGTAGAGACCAAAAGGTAGAGAGATGACAGAAG
GGAGACTCTGATTAGTGTATTTTTTTTTTGTCTATTCCTTAAAGCCCAGACACCTTTCCATTAAAATCTACTTCAAATCACAAGTTGATT
ACAATTGAGTGGAACATCCCATGTTGTAAATGGAATAATGTGTTCAGAATGCTCTTTCTTTCCCCCAATAAAGCCCTTTATAGTGTTT

>91068_91068_2_TJP2-TMEM38B_TJP2_chr9_71845148_ENST00000265384_TMEM38B_chr9_108536146_ENST00000374692_length(amino acids)=638AA_BP=567
MRAYAGPVSEMPVRGDRGFPPRRELSGWLRAPGMEELIWEQYTVTLQKDSKRGFGIAVSGGRDNPHFENGETSIVISDVLPGGPADGLLQ
ENDRVVMVNGTPMEDVLHSFAVQQLRKSGKVAAIVVKRPRKVQVAALQASPPLDQDDRAFEVMDEFDGRSFRSGYSERSRLNSHGGRSRS
WEDSPERGRPHERARSRERDLSRDRSRGRSLERGLDQDHARTRDRSRGRSLERGLDHDFGPSRDRDRDRSRGRSIDQDYERAYHRAYDPD
YERAYSPEYRRGARHDARSRGPRSRSREHPHSRSPSPEPRGRPGPIGVLLMKSRANEEYGLRLGSQIFVKEMTRTGLATKDGNLHEGDII
LKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSQQTLINIPSLNDSDSEIEDISEIESNRSFSPEERRHQYSDYDYHSSSEKLKERPS
SREDTPSRLSRMGATPTPFKSTGDIAGTVVPETNKEPRYQEDPPAPQPKAAPRTFLRPSPEDEAIYGPNTKMVRFKKGDSVGLRLAGGND
VGIFVAGIQEGTSAEQEGLQEGDQILKITMMTTQTSTMTFAPFEDTLSWMLFGWQQPFSSCEKKSEAKSPSNGVGSLASKPVDVASDNVK
KKHTKKNE

--------------------------------------------------------------
>91068_91068_3_TJP2-TMEM38B_TJP2_chr9_71845148_ENST00000348208_TMEM38B_chr9_108536146_ENST00000374688_length(transcript)=4515nt_BP=1767nt
AGAGCACTGTCCGGTGGTGCCCAGGAGGAGTAGGAGCAGGAGCAGAAGCAGAAGCGGGGTCCGGAGCTGCGCGCCTACGCGGGACCTGTG
TCCGAAATGCCGGTGCGAGGAGACCGCGGGTTTCCACCCCGGCGGGAGCTGTCAGGTTGGCTCCGCGCCCCAGGCATGGAAGAGCTGATA
TGGGAACAGTACACTGTGACCCTACAAAAGGATTCCAAAAGAGGATTTGGAATTGCAGTGTCCGGAGGCAGAGACAACCCCCACTTTGAA
AATGGAGAAACGTCAATTGTCATTTCTGATGTGCTCCCGGGTGGGCCTGCTGATGGGCTGCTCCAAGAAAATGACAGAGTGGTCATGGTC
AATGGCACCCCCATGGAGGATGTGCTTCATTCGTTTGCAGTTCAGCAGCTCAGAAAAAGTGGGAAGGTCGCTGCTATTGTGGTCAAGAGG
CCCCGGAAGGTCCAGGTGGCCGCACTTCAGGCCAGCCCTCCCCTGGATCAGGATGACCGGGCTTTTGAGGTGATGGACGAGTTTGATGGC
AGAAGTTTCCGGAGTGGCTACAGCGAGAGGAGCCGGCTGAACAGCCATGGGGGGCGCAGCCGCAGCTGGGAGGACAGCCCGGAAAGGGGG
CGTCCCCATGAGCGGGCCCGGAGCCGGGAGCGGGACCTCAGCCGGGACCGGAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCAAGAC
CATGCGCGCACCCGAGACCGCAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCACGACTTTGGGCCATCCCGGGACCGGGACCGTGAC
CGCAGCCGCGGCCGGAGCATTGACCAGGACTACGAGCGAGCCTATCACCGGGCCTACGACCCAGACTACGAGCGGGCCTACAGCCCGGAG
TACAGGCGCGGGGCCCGCCACGATGCCCGCTCTCGGGGACCCCGAAGCCGCAGCCGCGAGCACCCGCACTCACGGAGCCCCAGCCCCGAG
CCTAGGGGGCGGCCGGGGCCCATCGGGGTCCTCCTGATGAAAAGCAGAGCGAACGAAGAGTATGGTCTCCGGCTTGGGAGTCAGATCTTC
GTAAAGGAAATGACCCGAACGGGTCTGGCAACTAAAGATGGCAACCTTCACGAAGGAGACATAATTCTCAAGATCAATGGGACTGTAACT
GAGAACATGTCTTTAACGGATGCTCGAAAATTGATAGAAAAGTCAAGAGGAAAACTACAGCTAGTGGTGTTGAGAGACAGCCAGCAGACC
CTCATCAACATCCCGTCATTAAATGACAGTGACTCAGAAATAGAAGATATTTCAGAAATAGAGTCAAACCGATCATTTTCTCCAGAGGAG
AGACGTCATCAGTATTCTGATTATGATTATCATTCCTCAAGTGAGAAGCTGAAGGAAAGGCCAAGTTCCAGAGAGGACACGCCGAGCAGA
TTGTCCAGGATGGGTGCGACACCCACTCCCTTTAAGTCCACAGGGGATATTGCAGGCACAGTTGTCCCAGAGACCAACAAGGAACCCAGA
TACCAAGAGGACCCCCCAGCTCCTCAACCAAAAGCAGCCCCGAGAACTTTTCTTCGTCCTAGTCCTGAAGATGAAGCAATATATGGCCCT
AATACCAAAATGGTAAGGTTCAAGAAGGGAGACAGCGTGGGCCTCCGGTTGGCTGGTGGCAATGATGTCGGGATATTTGTTGCTGGCATT
CAAGAAGGGACCTCGGCGGAGCAGGAGGGCCTTCAAGAAGGAGACCAGATTCTGAAGATAACCATGATGACTACACAGACTTCTACTATG
ACATTTGCTCCTTTTGAGGATACATTGAGTTGGATGCTATTTGGCTGGCAGCAGCCGTTTTCATCATGTGAGAAGAAAAGTGAAGCAAAG
TCACCTTCCAATGGCGTTGGGTCATTGGCCTCAAAGCCGGTAGATGTTGCCTCAGATAATGTTAAAAAGAAACATACTAAGAAGAATGAA
TAAATTTACGTGATGAGCTCTACAAGGCCAAAAATTTTTTTTCTTATCTACCTGTTATATTGTGCTAATTTTTCTATGTATGTGATGTGA
AATGAAGACTATATATATGGAATGGAGGTGACAGAAAGAAAGAAATTCTTTGTTTGAGGGAGACTTCCCCTTTCTGGATTGTATTTGTAG
AGTGTTACGAGTGTATCATGTGATTATGCTTTACCGGTATAAGAGATTCTGTTGTGATTATTTGAATAGTTTTATATTAATAAAAGAAGA
CAAAATTTTTTAAATGTTAGAAAAAGCAGATCTGTCATTGCAAAGTAACAAAAATTTTAAGCTTTTAAAAATGTAGATTTTTCATATTTT
TAAAATTTGAATCTATTTGAGCTTTAGTTCAGCAGAATTAAATTTTTACTTGACATTATCATTAAAATTGCTAGGTATGGAGAACAATTC
CTATTTTATTTTGAACACTGAGAAGAGTAAACTTTTCCTAAAACACTTTATATTATAAATGAAAATAAATTGCTAGTTTATATTTTAGAT
ATAAACATCATATTTTTTATTAATACCTACATCAAATGGAAAATATCTGAAATTTTTTTTCCATAGCAGGTATTTTCTACTAGAAGTAGT
TTTACTACTTTTCATTTAGAACAGAGTATGAGTCTTAATCTGAAGTCTTTTTCATGCCCTTGTTTTAAAAAAACTACTTTTTTTGGCCTC
AAAAAAATCAAGGGTGTAATTTTTAATAAATTGTTAATCCTATGTTTTGTAATTTTCATTTTAGGAGCTTGACTTATTTTTTTCTCTCTC
ATAAAAACACATTTGTTTTAATTGTAGGAGAAATTTTCTCAGCATTTTGCATGTTCTTTCTAATCTTTGTTGGTCTGAATATATTGGTAG
TAATTACTGTAATTATTCAACAAAAAGCATATCCGTTCAAAAATTTTTCCACTATGTCTTTTTTCTAGTGGCTACTGTTTTAGTTTTCTA
GTTGAATATCTCTGACAAGCTTTCGTATGGTTTTGTTATATTTTCATCTACATGTAATGTGTTATTAATTTTATTAAATGAAAACTAATC
ACCTTCATGTGGAAATGCTCTGAGAATTGTCCTTAGGCATTTGGTAGTAACCAGCTAACCAAGAAGAAACAGAGAAACCAGAACTTCATA
TGGCAGTCCATTTAGATGAAGAATGATGATATAAAATCTGGTTCCTTCTTAGCAAAATAAAAAACAAACAAGAAAAGATACTAAATGATG
TTAATTTTCTTACTTTATGATTTAGAAGTCCAGTTATAATATTAAAACTCTGTGACATAGTTTCTTTTACCAAAACCATGAACCTACTCC
CCGTATCAGGTATTTTCGATGGTTTAGAAGTACTCAAGTCACATCACATTCAAGTTAGAAGTTTTTTTTTTGTTGTTGTTATTTTAAATT
TTTAACAAATATAAACACCAGCAGATACTATTACTTGCTTAAAAAATTGGGAGGGGGCACTTTTCATAGTCTTGGAATGCTAAGAAGTTT
TATTTTTAATATTGTGACAGAAAGCTTTAAGTATTTAAGAGCTCTGTATTATATTTGATACTCTTACAGTTAAAAACTTTTCAAAATTAA
TACATTGTTAATTATTGACCAGTTTTGAAGTTTGGGTTTAACTGTAGTTGAAATGGAAGGACTCTTGTTTTACACTTGTATTAAAGATAA
ATTTATTAAAATAAGTTATTTAGCACCAATGGAGTATTACATTATTTTTATGTTTTATATTTTTCTTGAGGTAGAGTTTCAGAACTCATC
TAGTATTTTGACTAATATAGTATATATTCAGTGATTACTGTTCAAATGGGACATTGGTAGAAACTTTATTAATCTATGCAAGTATCCTAT
AACCCTCAATTCAAGGCTCTTTTGTAAAAAATGTACTGGAGAACATGGCTTAGGCCTGAAACCCATCCTGAATCTATTCAGGTCACCTGT
AGAGTCTTGACTTGGATTTGCAAAGCAGATTGTTAGACTCCTTACCCAATGTGAAGTGTGAATAAGGCCTATAGGCCTGCCTCACACAGC
TAATCAGAGGTGGCACTGAGAAAGTCAAGTCCTAATAGGTCTCCTTAAAAAAAAAAAGGAGACAAAAAGCTGGCAAGAACATGAGCCAGC
TTCCCTCAGTGCTGTCACTCTCAAGTAAAACATGGCCAAATGAATATCAAACTGGTTTATCAGATTAGTCACTCTTCCTTACTGAGGGAG
TATCAAGTAAGGGCTGGAGAGAGACCAGATATGTGGAGTTGTTGGCTTTCAGTGGAAATGGTAGCCTCCCTGTGGGTAGAGACCAAAAGG
TAGAGAGATGACAGAAGGGAGACTCTGATTAGTGTATTTTTTTTTTGTCTATTCCTTAAAGCCCAGACACCTTTCCATTAAAATCTACTT
CAAATCACAAGTTGATTACAATTGAGTGGAACATCCCATGTTGTAAATGGAATAATGTGTTCAGAATGCTCTTTCTTTCCCCCAATAAAG
CCCTTTATAGTGTTT

>91068_91068_3_TJP2-TMEM38B_TJP2_chr9_71845148_ENST00000348208_TMEM38B_chr9_108536146_ENST00000374688_length(amino acids)=638AA_BP=567
MRAYAGPVSEMPVRGDRGFPPRRELSGWLRAPGMEELIWEQYTVTLQKDSKRGFGIAVSGGRDNPHFENGETSIVISDVLPGGPADGLLQ
ENDRVVMVNGTPMEDVLHSFAVQQLRKSGKVAAIVVKRPRKVQVAALQASPPLDQDDRAFEVMDEFDGRSFRSGYSERSRLNSHGGRSRS
WEDSPERGRPHERARSRERDLSRDRSRGRSLERGLDQDHARTRDRSRGRSLERGLDHDFGPSRDRDRDRSRGRSIDQDYERAYHRAYDPD
YERAYSPEYRRGARHDARSRGPRSRSREHPHSRSPSPEPRGRPGPIGVLLMKSRANEEYGLRLGSQIFVKEMTRTGLATKDGNLHEGDII
LKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSQQTLINIPSLNDSDSEIEDISEIESNRSFSPEERRHQYSDYDYHSSSEKLKERPS
SREDTPSRLSRMGATPTPFKSTGDIAGTVVPETNKEPRYQEDPPAPQPKAAPRTFLRPSPEDEAIYGPNTKMVRFKKGDSVGLRLAGGND
VGIFVAGIQEGTSAEQEGLQEGDQILKITMMTTQTSTMTFAPFEDTLSWMLFGWQQPFSSCEKKSEAKSPSNGVGSLASKPVDVASDNVK
KKHTKKNE

--------------------------------------------------------------
>91068_91068_4_TJP2-TMEM38B_TJP2_chr9_71845148_ENST00000348208_TMEM38B_chr9_108536146_ENST00000374692_length(transcript)=4515nt_BP=1767nt
AGAGCACTGTCCGGTGGTGCCCAGGAGGAGTAGGAGCAGGAGCAGAAGCAGAAGCGGGGTCCGGAGCTGCGCGCCTACGCGGGACCTGTG
TCCGAAATGCCGGTGCGAGGAGACCGCGGGTTTCCACCCCGGCGGGAGCTGTCAGGTTGGCTCCGCGCCCCAGGCATGGAAGAGCTGATA
TGGGAACAGTACACTGTGACCCTACAAAAGGATTCCAAAAGAGGATTTGGAATTGCAGTGTCCGGAGGCAGAGACAACCCCCACTTTGAA
AATGGAGAAACGTCAATTGTCATTTCTGATGTGCTCCCGGGTGGGCCTGCTGATGGGCTGCTCCAAGAAAATGACAGAGTGGTCATGGTC
AATGGCACCCCCATGGAGGATGTGCTTCATTCGTTTGCAGTTCAGCAGCTCAGAAAAAGTGGGAAGGTCGCTGCTATTGTGGTCAAGAGG
CCCCGGAAGGTCCAGGTGGCCGCACTTCAGGCCAGCCCTCCCCTGGATCAGGATGACCGGGCTTTTGAGGTGATGGACGAGTTTGATGGC
AGAAGTTTCCGGAGTGGCTACAGCGAGAGGAGCCGGCTGAACAGCCATGGGGGGCGCAGCCGCAGCTGGGAGGACAGCCCGGAAAGGGGG
CGTCCCCATGAGCGGGCCCGGAGCCGGGAGCGGGACCTCAGCCGGGACCGGAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCAAGAC
CATGCGCGCACCCGAGACCGCAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCACGACTTTGGGCCATCCCGGGACCGGGACCGTGAC
CGCAGCCGCGGCCGGAGCATTGACCAGGACTACGAGCGAGCCTATCACCGGGCCTACGACCCAGACTACGAGCGGGCCTACAGCCCGGAG
TACAGGCGCGGGGCCCGCCACGATGCCCGCTCTCGGGGACCCCGAAGCCGCAGCCGCGAGCACCCGCACTCACGGAGCCCCAGCCCCGAG
CCTAGGGGGCGGCCGGGGCCCATCGGGGTCCTCCTGATGAAAAGCAGAGCGAACGAAGAGTATGGTCTCCGGCTTGGGAGTCAGATCTTC
GTAAAGGAAATGACCCGAACGGGTCTGGCAACTAAAGATGGCAACCTTCACGAAGGAGACATAATTCTCAAGATCAATGGGACTGTAACT
GAGAACATGTCTTTAACGGATGCTCGAAAATTGATAGAAAAGTCAAGAGGAAAACTACAGCTAGTGGTGTTGAGAGACAGCCAGCAGACC
CTCATCAACATCCCGTCATTAAATGACAGTGACTCAGAAATAGAAGATATTTCAGAAATAGAGTCAAACCGATCATTTTCTCCAGAGGAG
AGACGTCATCAGTATTCTGATTATGATTATCATTCCTCAAGTGAGAAGCTGAAGGAAAGGCCAAGTTCCAGAGAGGACACGCCGAGCAGA
TTGTCCAGGATGGGTGCGACACCCACTCCCTTTAAGTCCACAGGGGATATTGCAGGCACAGTTGTCCCAGAGACCAACAAGGAACCCAGA
TACCAAGAGGACCCCCCAGCTCCTCAACCAAAAGCAGCCCCGAGAACTTTTCTTCGTCCTAGTCCTGAAGATGAAGCAATATATGGCCCT
AATACCAAAATGGTAAGGTTCAAGAAGGGAGACAGCGTGGGCCTCCGGTTGGCTGGTGGCAATGATGTCGGGATATTTGTTGCTGGCATT
CAAGAAGGGACCTCGGCGGAGCAGGAGGGCCTTCAAGAAGGAGACCAGATTCTGAAGATAACCATGATGACTACACAGACTTCTACTATG
ACATTTGCTCCTTTTGAGGATACATTGAGTTGGATGCTATTTGGCTGGCAGCAGCCGTTTTCATCATGTGAGAAGAAAAGTGAAGCAAAG
TCACCTTCCAATGGCGTTGGGTCATTGGCCTCAAAGCCGGTAGATGTTGCCTCAGATAATGTTAAAAAGAAACATACTAAGAAGAATGAA
TAAATTTACGTGATGAGCTCTACAAGGCCAAAAATTTTTTTTCTTATCTACCTGTTATATTGTGCTAATTTTTCTATGTATGTGATGTGA
AATGAAGACTATATATATGGAATGGAGGTGACAGAAAGAAAGAAATTCTTTGTTTGAGGGAGACTTCCCCTTTCTGGATTGTATTTGTAG
AGTGTTACGAGTGTATCATGTGATTATGCTTTACCGGTATAAGAGATTCTGTTGTGATTATTTGAATAGTTTTATATTAATAAAAGAAGA
CAAAATTTTTTAAATGTTAGAAAAAGCAGATCTGTCATTGCAAAGTAACAAAAATTTTAAGCTTTTAAAAATGTAGATTTTTCATATTTT
TAAAATTTGAATCTATTTGAGCTTTAGTTCAGCAGAATTAAATTTTTACTTGACATTATCATTAAAATTGCTAGGTATGGAGAACAATTC
CTATTTTATTTTGAACACTGAGAAGAGTAAACTTTTCCTAAAACACTTTATATTATAAATGAAAATAAATTGCTAGTTTATATTTTAGAT
ATAAACATCATATTTTTTATTAATACCTACATCAAATGGAAAATATCTGAAATTTTTTTTCCATAGCAGGTATTTTCTACTAGAAGTAGT
TTTACTACTTTTCATTTAGAACAGAGTATGAGTCTTAATCTGAAGTCTTTTTCATGCCCTTGTTTTAAAAAAACTACTTTTTTTGGCCTC
AAAAAAATCAAGGGTGTAATTTTTAATAAATTGTTAATCCTATGTTTTGTAATTTTCATTTTAGGAGCTTGACTTATTTTTTTCTCTCTC
ATAAAAACACATTTGTTTTAATTGTAGGAGAAATTTTCTCAGCATTTTGCATGTTCTTTCTAATCTTTGTTGGTCTGAATATATTGGTAG
TAATTACTGTAATTATTCAACAAAAAGCATATCCGTTCAAAAATTTTTCCACTATGTCTTTTTTCTAGTGGCTACTGTTTTAGTTTTCTA
GTTGAATATCTCTGACAAGCTTTCGTATGGTTTTGTTATATTTTCATCTACATGTAATGTGTTATTAATTTTATTAAATGAAAACTAATC
ACCTTCATGTGGAAATGCTCTGAGAATTGTCCTTAGGCATTTGGTAGTAACCAGCTAACCAAGAAGAAACAGAGAAACCAGAACTTCATA
TGGCAGTCCATTTAGATGAAGAATGATGATATAAAATCTGGTTCCTTCTTAGCAAAATAAAAAACAAACAAGAAAAGATACTAAATGATG
TTAATTTTCTTACTTTATGATTTAGAAGTCCAGTTATAATATTAAAACTCTGTGACATAGTTTCTTTTACCAAAACCATGAACCTACTCC
CCGTATCAGGTATTTTCGATGGTTTAGAAGTACTCAAGTCACATCACATTCAAGTTAGAAGTTTTTTTTTTGTTGTTGTTATTTTAAATT
TTTAACAAATATAAACACCAGCAGATACTATTACTTGCTTAAAAAATTGGGAGGGGGCACTTTTCATAGTCTTGGAATGCTAAGAAGTTT
TATTTTTAATATTGTGACAGAAAGCTTTAAGTATTTAAGAGCTCTGTATTATATTTGATACTCTTACAGTTAAAAACTTTTCAAAATTAA
TACATTGTTAATTATTGACCAGTTTTGAAGTTTGGGTTTAACTGTAGTTGAAATGGAAGGACTCTTGTTTTACACTTGTATTAAAGATAA
ATTTATTAAAATAAGTTATTTAGCACCAATGGAGTATTACATTATTTTTATGTTTTATATTTTTCTTGAGGTAGAGTTTCAGAACTCATC
TAGTATTTTGACTAATATAGTATATATTCAGTGATTACTGTTCAAATGGGACATTGGTAGAAACTTTATTAATCTATGCAAGTATCCTAT
AACCCTCAATTCAAGGCTCTTTTGTAAAAAATGTACTGGAGAACATGGCTTAGGCCTGAAACCCATCCTGAATCTATTCAGGTCACCTGT
AGAGTCTTGACTTGGATTTGCAAAGCAGATTGTTAGACTCCTTACCCAATGTGAAGTGTGAATAAGGCCTATAGGCCTGCCTCACACAGC
TAATCAGAGGTGGCACTGAGAAAGTCAAGTCCTAATAGGTCTCCTTAAAAAAAAAAAGGAGACAAAAAGCTGGCAAGAACATGAGCCAGC
TTCCCTCAGTGCTGTCACTCTCAAGTAAAACATGGCCAAATGAATATCAAACTGGTTTATCAGATTAGTCACTCTTCCTTACTGAGGGAG
TATCAAGTAAGGGCTGGAGAGAGACCAGATATGTGGAGTTGTTGGCTTTCAGTGGAAATGGTAGCCTCCCTGTGGGTAGAGACCAAAAGG
TAGAGAGATGACAGAAGGGAGACTCTGATTAGTGTATTTTTTTTTTGTCTATTCCTTAAAGCCCAGACACCTTTCCATTAAAATCTACTT
CAAATCACAAGTTGATTACAATTGAGTGGAACATCCCATGTTGTAAATGGAATAATGTGTTCAGAATGCTCTTTCTTTCCCCCAATAAAG
CCCTTTATAGTGTTT

>91068_91068_4_TJP2-TMEM38B_TJP2_chr9_71845148_ENST00000348208_TMEM38B_chr9_108536146_ENST00000374692_length(amino acids)=638AA_BP=567
MRAYAGPVSEMPVRGDRGFPPRRELSGWLRAPGMEELIWEQYTVTLQKDSKRGFGIAVSGGRDNPHFENGETSIVISDVLPGGPADGLLQ
ENDRVVMVNGTPMEDVLHSFAVQQLRKSGKVAAIVVKRPRKVQVAALQASPPLDQDDRAFEVMDEFDGRSFRSGYSERSRLNSHGGRSRS
WEDSPERGRPHERARSRERDLSRDRSRGRSLERGLDQDHARTRDRSRGRSLERGLDHDFGPSRDRDRDRSRGRSIDQDYERAYHRAYDPD
YERAYSPEYRRGARHDARSRGPRSRSREHPHSRSPSPEPRGRPGPIGVLLMKSRANEEYGLRLGSQIFVKEMTRTGLATKDGNLHEGDII
LKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSQQTLINIPSLNDSDSEIEDISEIESNRSFSPEERRHQYSDYDYHSSSEKLKERPS
SREDTPSRLSRMGATPTPFKSTGDIAGTVVPETNKEPRYQEDPPAPQPKAAPRTFLRPSPEDEAIYGPNTKMVRFKKGDSVGLRLAGGND
VGIFVAGIQEGTSAEQEGLQEGDQILKITMMTTQTSTMTFAPFEDTLSWMLFGWQQPFSSCEKKSEAKSPSNGVGSLASKPVDVASDNVK
KKHTKKNE

--------------------------------------------------------------
>91068_91068_5_TJP2-TMEM38B_TJP2_chr9_71845148_ENST00000377245_TMEM38B_chr9_108536146_ENST00000374688_length(transcript)=4627nt_BP=1879nt
GCGGAGGCGCCACGCTCGGGTCGGGGGCGGGCTGACGCCGCCGCCGCCGCGGGAGGAGGGACAAAGGGGTGGGTCCCCGCGGGTCGGCAC
CCCGGCGGTTGGGCTGCGGGTCAGAGCACTGTCCGGTGGTGCCCAGGAGGAGTAGGAGCAGGAGCAGAAGCAGAAGCGGGGTCCGGAGCT
GCGCGCCTACGCGGGACCTGTGTCCGAAATGCCGGTGCGAGGAGACCGCGGGTTTCCACCCCGGCGGGAGCTGTCAGGTTGGCTCCGCGC
CCCAGGCATGGAAGAGCTGATATGGGAACAGTACACTGTGACCCTACAAAAGGATTCCAAAAGAGGATTTGGAATTGCAGTGTCCGGAGG
CAGAGACAACCCCCACTTTGAAAATGGAGAAACGTCAATTGTCATTTCTGATGTGCTCCCGGGTGGGCCTGCTGATGGGCTGCTCCAAGA
AAATGACAGAGTGGTCATGGTCAATGGCACCCCCATGGAGGATGTGCTTCATTCGTTTGCAGTTCAGCAGCTCAGAAAAAGTGGGAAGGT
CGCTGCTATTGTGGTCAAGAGGCCCCGGAAGGTCCAGGTGGCCGCACTTCAGGCCAGCCCTCCCCTGGATCAGGATGACCGGGCTTTTGA
GGTGATGGACGAGTTTGATGGCAGAAGTTTCCGGAGTGGCTACAGCGAGAGGAGCCGGCTGAACAGCCATGGGGGGCGCAGCCGCAGCTG
GGAGGACAGCCCGGAAAGGGGGCGTCCCCATGAGCGGGCCCGGAGCCGGGAGCGGGACCTCAGCCGGGACCGGAGCCGTGGCCGGAGCCT
GGAGCGGGGCCTGGACCAAGACCATGCGCGCACCCGAGACCGCAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCACGACTTTGGGCC
ATCCCGGGACCGGGACCGTGACCGCAGCCGCGGCCGGAGCATTGACCAGGACTACGAGCGAGCCTATCACCGGGCCTACGACCCAGACTA
CGAGCGGGCCTACAGCCCGGAGTACAGGCGCGGGGCCCGCCACGATGCCCGCTCTCGGGGACCCCGAAGCCGCAGCCGCGAGCACCCGCA
CTCACGGAGCCCCAGCCCCGAGCCTAGGGGGCGGCCGGGGCCCATCGGGGTCCTCCTGATGAAAAGCAGAGCGAACGAAGAGTATGGTCT
CCGGCTTGGGAGTCAGATCTTCGTAAAGGAAATGACCCGAACGGGTCTGGCAACTAAAGATGGCAACCTTCACGAAGGAGACATAATTCT
CAAGATCAATGGGACTGTAACTGAGAACATGTCTTTAACGGATGCTCGAAAATTGATAGAAAAGTCAAGAGGAAAACTACAGCTAGTGGT
GTTGAGAGACAGCCAGCAGACCCTCATCAACATCCCGTCATTAAATGACAGTGACTCAGAAATAGAAGATATTTCAGAAATAGAGTCAAA
CCGATCATTTTCTCCAGAGGAGAGACGTCATCAGTATTCTGATTATGATTATCATTCCTCAAGTGAGAAGCTGAAGGAAAGGCCAAGTTC
CAGAGAGGACACGCCGAGCAGATTGTCCAGGATGGGTGCGACACCCACTCCCTTTAAGTCCACAGGGGATATTGCAGGCACAGTTGTCCC
AGAGACCAACAAGGAACCCAGATACCAAGAGGACCCCCCAGCTCCTCAACCAAAAGCAGCCCCGAGAACTTTTCTTCGTCCTAGTCCTGA
AGATGAAGCAATATATGGCCCTAATACCAAAATGGTAAGGTTCAAGAAGGGAGACAGCGTGGGCCTCCGGTTGGCTGGTGGCAATGATGT
CGGGATATTTGTTGCTGGCATTCAAGAAGGGACCTCGGCGGAGCAGGAGGGCCTTCAAGAAGGAGACCAGATTCTGAAGATAACCATGAT
GACTACACAGACTTCTACTATGACATTTGCTCCTTTTGAGGATACATTGAGTTGGATGCTATTTGGCTGGCAGCAGCCGTTTTCATCATG
TGAGAAGAAAAGTGAAGCAAAGTCACCTTCCAATGGCGTTGGGTCATTGGCCTCAAAGCCGGTAGATGTTGCCTCAGATAATGTTAAAAA
GAAACATACTAAGAAGAATGAATAAATTTACGTGATGAGCTCTACAAGGCCAAAAATTTTTTTTCTTATCTACCTGTTATATTGTGCTAA
TTTTTCTATGTATGTGATGTGAAATGAAGACTATATATATGGAATGGAGGTGACAGAAAGAAAGAAATTCTTTGTTTGAGGGAGACTTCC
CCTTTCTGGATTGTATTTGTAGAGTGTTACGAGTGTATCATGTGATTATGCTTTACCGGTATAAGAGATTCTGTTGTGATTATTTGAATA
GTTTTATATTAATAAAAGAAGACAAAATTTTTTAAATGTTAGAAAAAGCAGATCTGTCATTGCAAAGTAACAAAAATTTTAAGCTTTTAA
AAATGTAGATTTTTCATATTTTTAAAATTTGAATCTATTTGAGCTTTAGTTCAGCAGAATTAAATTTTTACTTGACATTATCATTAAAAT
TGCTAGGTATGGAGAACAATTCCTATTTTATTTTGAACACTGAGAAGAGTAAACTTTTCCTAAAACACTTTATATTATAAATGAAAATAA
ATTGCTAGTTTATATTTTAGATATAAACATCATATTTTTTATTAATACCTACATCAAATGGAAAATATCTGAAATTTTTTTTCCATAGCA
GGTATTTTCTACTAGAAGTAGTTTTACTACTTTTCATTTAGAACAGAGTATGAGTCTTAATCTGAAGTCTTTTTCATGCCCTTGTTTTAA
AAAAACTACTTTTTTTGGCCTCAAAAAAATCAAGGGTGTAATTTTTAATAAATTGTTAATCCTATGTTTTGTAATTTTCATTTTAGGAGC
TTGACTTATTTTTTTCTCTCTCATAAAAACACATTTGTTTTAATTGTAGGAGAAATTTTCTCAGCATTTTGCATGTTCTTTCTAATCTTT
GTTGGTCTGAATATATTGGTAGTAATTACTGTAATTATTCAACAAAAAGCATATCCGTTCAAAAATTTTTCCACTATGTCTTTTTTCTAG
TGGCTACTGTTTTAGTTTTCTAGTTGAATATCTCTGACAAGCTTTCGTATGGTTTTGTTATATTTTCATCTACATGTAATGTGTTATTAA
TTTTATTAAATGAAAACTAATCACCTTCATGTGGAAATGCTCTGAGAATTGTCCTTAGGCATTTGGTAGTAACCAGCTAACCAAGAAGAA
ACAGAGAAACCAGAACTTCATATGGCAGTCCATTTAGATGAAGAATGATGATATAAAATCTGGTTCCTTCTTAGCAAAATAAAAAACAAA
CAAGAAAAGATACTAAATGATGTTAATTTTCTTACTTTATGATTTAGAAGTCCAGTTATAATATTAAAACTCTGTGACATAGTTTCTTTT
ACCAAAACCATGAACCTACTCCCCGTATCAGGTATTTTCGATGGTTTAGAAGTACTCAAGTCACATCACATTCAAGTTAGAAGTTTTTTT
TTTGTTGTTGTTATTTTAAATTTTTAACAAATATAAACACCAGCAGATACTATTACTTGCTTAAAAAATTGGGAGGGGGCACTTTTCATA
GTCTTGGAATGCTAAGAAGTTTTATTTTTAATATTGTGACAGAAAGCTTTAAGTATTTAAGAGCTCTGTATTATATTTGATACTCTTACA
GTTAAAAACTTTTCAAAATTAATACATTGTTAATTATTGACCAGTTTTGAAGTTTGGGTTTAACTGTAGTTGAAATGGAAGGACTCTTGT
TTTACACTTGTATTAAAGATAAATTTATTAAAATAAGTTATTTAGCACCAATGGAGTATTACATTATTTTTATGTTTTATATTTTTCTTG
AGGTAGAGTTTCAGAACTCATCTAGTATTTTGACTAATATAGTATATATTCAGTGATTACTGTTCAAATGGGACATTGGTAGAAACTTTA
TTAATCTATGCAAGTATCCTATAACCCTCAATTCAAGGCTCTTTTGTAAAAAATGTACTGGAGAACATGGCTTAGGCCTGAAACCCATCC
TGAATCTATTCAGGTCACCTGTAGAGTCTTGACTTGGATTTGCAAAGCAGATTGTTAGACTCCTTACCCAATGTGAAGTGTGAATAAGGC
CTATAGGCCTGCCTCACACAGCTAATCAGAGGTGGCACTGAGAAAGTCAAGTCCTAATAGGTCTCCTTAAAAAAAAAAAGGAGACAAAAA
GCTGGCAAGAACATGAGCCAGCTTCCCTCAGTGCTGTCACTCTCAAGTAAAACATGGCCAAATGAATATCAAACTGGTTTATCAGATTAG
TCACTCTTCCTTACTGAGGGAGTATCAAGTAAGGGCTGGAGAGAGACCAGATATGTGGAGTTGTTGGCTTTCAGTGGAAATGGTAGCCTC
CCTGTGGGTAGAGACCAAAAGGTAGAGAGATGACAGAAGGGAGACTCTGATTAGTGTATTTTTTTTTTGTCTATTCCTTAAAGCCCAGAC
ACCTTTCCATTAAAATCTACTTCAAATCACAAGTTGATTACAATTGAGTGGAACATCCCATGTTGTAAATGGAATAATGTGTTCAGAATG
CTCTTTCTTTCCCCCAATAAAGCCCTTTATAGTGTTT

>91068_91068_5_TJP2-TMEM38B_TJP2_chr9_71845148_ENST00000377245_TMEM38B_chr9_108536146_ENST00000374688_length(amino acids)=638AA_BP=567
MRAYAGPVSEMPVRGDRGFPPRRELSGWLRAPGMEELIWEQYTVTLQKDSKRGFGIAVSGGRDNPHFENGETSIVISDVLPGGPADGLLQ
ENDRVVMVNGTPMEDVLHSFAVQQLRKSGKVAAIVVKRPRKVQVAALQASPPLDQDDRAFEVMDEFDGRSFRSGYSERSRLNSHGGRSRS
WEDSPERGRPHERARSRERDLSRDRSRGRSLERGLDQDHARTRDRSRGRSLERGLDHDFGPSRDRDRDRSRGRSIDQDYERAYHRAYDPD
YERAYSPEYRRGARHDARSRGPRSRSREHPHSRSPSPEPRGRPGPIGVLLMKSRANEEYGLRLGSQIFVKEMTRTGLATKDGNLHEGDII
LKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSQQTLINIPSLNDSDSEIEDISEIESNRSFSPEERRHQYSDYDYHSSSEKLKERPS
SREDTPSRLSRMGATPTPFKSTGDIAGTVVPETNKEPRYQEDPPAPQPKAAPRTFLRPSPEDEAIYGPNTKMVRFKKGDSVGLRLAGGND
VGIFVAGIQEGTSAEQEGLQEGDQILKITMMTTQTSTMTFAPFEDTLSWMLFGWQQPFSSCEKKSEAKSPSNGVGSLASKPVDVASDNVK
KKHTKKNE

--------------------------------------------------------------
>91068_91068_6_TJP2-TMEM38B_TJP2_chr9_71845148_ENST00000377245_TMEM38B_chr9_108536146_ENST00000374692_length(transcript)=4627nt_BP=1879nt
GCGGAGGCGCCACGCTCGGGTCGGGGGCGGGCTGACGCCGCCGCCGCCGCGGGAGGAGGGACAAAGGGGTGGGTCCCCGCGGGTCGGCAC
CCCGGCGGTTGGGCTGCGGGTCAGAGCACTGTCCGGTGGTGCCCAGGAGGAGTAGGAGCAGGAGCAGAAGCAGAAGCGGGGTCCGGAGCT
GCGCGCCTACGCGGGACCTGTGTCCGAAATGCCGGTGCGAGGAGACCGCGGGTTTCCACCCCGGCGGGAGCTGTCAGGTTGGCTCCGCGC
CCCAGGCATGGAAGAGCTGATATGGGAACAGTACACTGTGACCCTACAAAAGGATTCCAAAAGAGGATTTGGAATTGCAGTGTCCGGAGG
CAGAGACAACCCCCACTTTGAAAATGGAGAAACGTCAATTGTCATTTCTGATGTGCTCCCGGGTGGGCCTGCTGATGGGCTGCTCCAAGA
AAATGACAGAGTGGTCATGGTCAATGGCACCCCCATGGAGGATGTGCTTCATTCGTTTGCAGTTCAGCAGCTCAGAAAAAGTGGGAAGGT
CGCTGCTATTGTGGTCAAGAGGCCCCGGAAGGTCCAGGTGGCCGCACTTCAGGCCAGCCCTCCCCTGGATCAGGATGACCGGGCTTTTGA
GGTGATGGACGAGTTTGATGGCAGAAGTTTCCGGAGTGGCTACAGCGAGAGGAGCCGGCTGAACAGCCATGGGGGGCGCAGCCGCAGCTG
GGAGGACAGCCCGGAAAGGGGGCGTCCCCATGAGCGGGCCCGGAGCCGGGAGCGGGACCTCAGCCGGGACCGGAGCCGTGGCCGGAGCCT
GGAGCGGGGCCTGGACCAAGACCATGCGCGCACCCGAGACCGCAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCACGACTTTGGGCC
ATCCCGGGACCGGGACCGTGACCGCAGCCGCGGCCGGAGCATTGACCAGGACTACGAGCGAGCCTATCACCGGGCCTACGACCCAGACTA
CGAGCGGGCCTACAGCCCGGAGTACAGGCGCGGGGCCCGCCACGATGCCCGCTCTCGGGGACCCCGAAGCCGCAGCCGCGAGCACCCGCA
CTCACGGAGCCCCAGCCCCGAGCCTAGGGGGCGGCCGGGGCCCATCGGGGTCCTCCTGATGAAAAGCAGAGCGAACGAAGAGTATGGTCT
CCGGCTTGGGAGTCAGATCTTCGTAAAGGAAATGACCCGAACGGGTCTGGCAACTAAAGATGGCAACCTTCACGAAGGAGACATAATTCT
CAAGATCAATGGGACTGTAACTGAGAACATGTCTTTAACGGATGCTCGAAAATTGATAGAAAAGTCAAGAGGAAAACTACAGCTAGTGGT
GTTGAGAGACAGCCAGCAGACCCTCATCAACATCCCGTCATTAAATGACAGTGACTCAGAAATAGAAGATATTTCAGAAATAGAGTCAAA
CCGATCATTTTCTCCAGAGGAGAGACGTCATCAGTATTCTGATTATGATTATCATTCCTCAAGTGAGAAGCTGAAGGAAAGGCCAAGTTC
CAGAGAGGACACGCCGAGCAGATTGTCCAGGATGGGTGCGACACCCACTCCCTTTAAGTCCACAGGGGATATTGCAGGCACAGTTGTCCC
AGAGACCAACAAGGAACCCAGATACCAAGAGGACCCCCCAGCTCCTCAACCAAAAGCAGCCCCGAGAACTTTTCTTCGTCCTAGTCCTGA
AGATGAAGCAATATATGGCCCTAATACCAAAATGGTAAGGTTCAAGAAGGGAGACAGCGTGGGCCTCCGGTTGGCTGGTGGCAATGATGT
CGGGATATTTGTTGCTGGCATTCAAGAAGGGACCTCGGCGGAGCAGGAGGGCCTTCAAGAAGGAGACCAGATTCTGAAGATAACCATGAT
GACTACACAGACTTCTACTATGACATTTGCTCCTTTTGAGGATACATTGAGTTGGATGCTATTTGGCTGGCAGCAGCCGTTTTCATCATG
TGAGAAGAAAAGTGAAGCAAAGTCACCTTCCAATGGCGTTGGGTCATTGGCCTCAAAGCCGGTAGATGTTGCCTCAGATAATGTTAAAAA
GAAACATACTAAGAAGAATGAATAAATTTACGTGATGAGCTCTACAAGGCCAAAAATTTTTTTTCTTATCTACCTGTTATATTGTGCTAA
TTTTTCTATGTATGTGATGTGAAATGAAGACTATATATATGGAATGGAGGTGACAGAAAGAAAGAAATTCTTTGTTTGAGGGAGACTTCC
CCTTTCTGGATTGTATTTGTAGAGTGTTACGAGTGTATCATGTGATTATGCTTTACCGGTATAAGAGATTCTGTTGTGATTATTTGAATA
GTTTTATATTAATAAAAGAAGACAAAATTTTTTAAATGTTAGAAAAAGCAGATCTGTCATTGCAAAGTAACAAAAATTTTAAGCTTTTAA
AAATGTAGATTTTTCATATTTTTAAAATTTGAATCTATTTGAGCTTTAGTTCAGCAGAATTAAATTTTTACTTGACATTATCATTAAAAT
TGCTAGGTATGGAGAACAATTCCTATTTTATTTTGAACACTGAGAAGAGTAAACTTTTCCTAAAACACTTTATATTATAAATGAAAATAA
ATTGCTAGTTTATATTTTAGATATAAACATCATATTTTTTATTAATACCTACATCAAATGGAAAATATCTGAAATTTTTTTTCCATAGCA
GGTATTTTCTACTAGAAGTAGTTTTACTACTTTTCATTTAGAACAGAGTATGAGTCTTAATCTGAAGTCTTTTTCATGCCCTTGTTTTAA
AAAAACTACTTTTTTTGGCCTCAAAAAAATCAAGGGTGTAATTTTTAATAAATTGTTAATCCTATGTTTTGTAATTTTCATTTTAGGAGC
TTGACTTATTTTTTTCTCTCTCATAAAAACACATTTGTTTTAATTGTAGGAGAAATTTTCTCAGCATTTTGCATGTTCTTTCTAATCTTT
GTTGGTCTGAATATATTGGTAGTAATTACTGTAATTATTCAACAAAAAGCATATCCGTTCAAAAATTTTTCCACTATGTCTTTTTTCTAG
TGGCTACTGTTTTAGTTTTCTAGTTGAATATCTCTGACAAGCTTTCGTATGGTTTTGTTATATTTTCATCTACATGTAATGTGTTATTAA
TTTTATTAAATGAAAACTAATCACCTTCATGTGGAAATGCTCTGAGAATTGTCCTTAGGCATTTGGTAGTAACCAGCTAACCAAGAAGAA
ACAGAGAAACCAGAACTTCATATGGCAGTCCATTTAGATGAAGAATGATGATATAAAATCTGGTTCCTTCTTAGCAAAATAAAAAACAAA
CAAGAAAAGATACTAAATGATGTTAATTTTCTTACTTTATGATTTAGAAGTCCAGTTATAATATTAAAACTCTGTGACATAGTTTCTTTT
ACCAAAACCATGAACCTACTCCCCGTATCAGGTATTTTCGATGGTTTAGAAGTACTCAAGTCACATCACATTCAAGTTAGAAGTTTTTTT
TTTGTTGTTGTTATTTTAAATTTTTAACAAATATAAACACCAGCAGATACTATTACTTGCTTAAAAAATTGGGAGGGGGCACTTTTCATA
GTCTTGGAATGCTAAGAAGTTTTATTTTTAATATTGTGACAGAAAGCTTTAAGTATTTAAGAGCTCTGTATTATATTTGATACTCTTACA
GTTAAAAACTTTTCAAAATTAATACATTGTTAATTATTGACCAGTTTTGAAGTTTGGGTTTAACTGTAGTTGAAATGGAAGGACTCTTGT
TTTACACTTGTATTAAAGATAAATTTATTAAAATAAGTTATTTAGCACCAATGGAGTATTACATTATTTTTATGTTTTATATTTTTCTTG
AGGTAGAGTTTCAGAACTCATCTAGTATTTTGACTAATATAGTATATATTCAGTGATTACTGTTCAAATGGGACATTGGTAGAAACTTTA
TTAATCTATGCAAGTATCCTATAACCCTCAATTCAAGGCTCTTTTGTAAAAAATGTACTGGAGAACATGGCTTAGGCCTGAAACCCATCC
TGAATCTATTCAGGTCACCTGTAGAGTCTTGACTTGGATTTGCAAAGCAGATTGTTAGACTCCTTACCCAATGTGAAGTGTGAATAAGGC
CTATAGGCCTGCCTCACACAGCTAATCAGAGGTGGCACTGAGAAAGTCAAGTCCTAATAGGTCTCCTTAAAAAAAAAAAGGAGACAAAAA
GCTGGCAAGAACATGAGCCAGCTTCCCTCAGTGCTGTCACTCTCAAGTAAAACATGGCCAAATGAATATCAAACTGGTTTATCAGATTAG
TCACTCTTCCTTACTGAGGGAGTATCAAGTAAGGGCTGGAGAGAGACCAGATATGTGGAGTTGTTGGCTTTCAGTGGAAATGGTAGCCTC
CCTGTGGGTAGAGACCAAAAGGTAGAGAGATGACAGAAGGGAGACTCTGATTAGTGTATTTTTTTTTTGTCTATTCCTTAAAGCCCAGAC
ACCTTTCCATTAAAATCTACTTCAAATCACAAGTTGATTACAATTGAGTGGAACATCCCATGTTGTAAATGGAATAATGTGTTCAGAATG
CTCTTTCTTTCCCCCAATAAAGCCCTTTATAGTGTTT

>91068_91068_6_TJP2-TMEM38B_TJP2_chr9_71845148_ENST00000377245_TMEM38B_chr9_108536146_ENST00000374692_length(amino acids)=638AA_BP=567
MRAYAGPVSEMPVRGDRGFPPRRELSGWLRAPGMEELIWEQYTVTLQKDSKRGFGIAVSGGRDNPHFENGETSIVISDVLPGGPADGLLQ
ENDRVVMVNGTPMEDVLHSFAVQQLRKSGKVAAIVVKRPRKVQVAALQASPPLDQDDRAFEVMDEFDGRSFRSGYSERSRLNSHGGRSRS
WEDSPERGRPHERARSRERDLSRDRSRGRSLERGLDQDHARTRDRSRGRSLERGLDHDFGPSRDRDRDRSRGRSIDQDYERAYHRAYDPD
YERAYSPEYRRGARHDARSRGPRSRSREHPHSRSPSPEPRGRPGPIGVLLMKSRANEEYGLRLGSQIFVKEMTRTGLATKDGNLHEGDII
LKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSQQTLINIPSLNDSDSEIEDISEIESNRSFSPEERRHQYSDYDYHSSSEKLKERPS
SREDTPSRLSRMGATPTPFKSTGDIAGTVVPETNKEPRYQEDPPAPQPKAAPRTFLRPSPEDEAIYGPNTKMVRFKKGDSVGLRLAGGND
VGIFVAGIQEGTSAEQEGLQEGDQILKITMMTTQTSTMTFAPFEDTLSWMLFGWQQPFSSCEKKSEAKSPSNGVGSLASKPVDVASDNVK
KKHTKKNE

--------------------------------------------------------------
>91068_91068_7_TJP2-TMEM38B_TJP2_chr9_71845148_ENST00000453658_TMEM38B_chr9_108536146_ENST00000374688_length(transcript)=4538nt_BP=1790nt
AGCTGCGTCTCCCTCCCGGGGCTCGCGCGCCCAGAACCCTCCGGTCTCAAGGAAGCAGGGTGCGAAGTACCACATTACTGTCATCTCCCT
GTGAGTGGGATTGGCACCCCGGCTGCAGCTCCAGGAGCAAGTACTCCAGGAAGCACAGAGCTGTACCAGTACACGGCCCACGTTGCCAGG
CCCCAGGCATGGAAGAGCTGATATGGGAACAGTACACTGTGACCCTACAAAAGGATTCCAAAAGAGGATTTGGAATTGCAGTGTCCGGAG
GCAGAGACAACCCCCACTTTGAAAATGGAGAAACGTCAATTGTCATTTCTGATGTGCTCCCGGGTGGGCCTGCTGATGGGCTGCTCCAAG
AAAATGACAGAGTGGTCATGGTCAATGGCACCCCCATGGAGGATGTGCTTCATTCGTTTGCAGTTCAGCAGCTCAGAAAAAGTGGGAAGG
TCGCTGCTATTGTGGTCAAGAGGCCCCGGAAGGTCCAGGTGGCCGCACTTCAGGCCAGCCCTCCCCTGGATCAGGATGACCGGGCTTTTG
AGGTGATGGACGAGTTTGATGGCAGAAGTTTCCGGAGTGGCTACAGCGAGAGGAGCCGGCTGAACAGCCATGGGGGGCGCAGCCGCAGCT
GGGAGGACAGCCCGGAAAGGGGGCGTCCCCATGAGCGGGCCCGGAGCCGGGAGCGGGACCTCAGCCGGGACCGGAGCCGTGGCCGGAGCC
TGGAGCGGGGCCTGGACCAAGACCATGCGCGCACCCGAGACCGCAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCACGACTTTGGGC
CATCCCGGGACCGGGACCGTGACCGCAGCCGCGGCCGGAGCATTGACCAGGACTACGAGCGAGCCTATCACCGGGCCTACGACCCAGACT
ACGAGCGGGCCTACAGCCCGGAGTACAGGCGCGGGGCCCGCCACGATGCCCGCTCTCGGGGACCCCGAAGCCGCAGCCGCGAGCACCCGC
ACTCACGGAGCCCCAGCCCCGAGCCTAGGGGGCGGCCGGGGCCCATCGGGGTCCTCCTGATGAAAAGCAGAGCGAACGAAGAGTATGGTC
TCCGGCTTGGGAGTCAGATCTTCGTAAAGGAAATGACCCGAACGGGTCTGGCAACTAAAGATGGCAACCTTCACGAAGGAGACATAATTC
TCAAGATCAATGGGACTGTAACTGAGAACATGTCTTTAACGGATGCTCGAAAATTGATAGAAAAGTCAAGAGGAAAACTACAGCTAGTGG
TGTTGAGAGACAGCCAGCAGACCCTCATCAACATCCCGTCATTAAATGACAGTGACTCAGAAATAGAAGATATTTCAGAAATAGAGTCAA
ACCGATCATTTTCTCCAGAGGAGAGACGTCATCAGTATTCTGATTATGATTATCATTCCTCAAGTGAGAAGCTGAAGGAAAGGCCAAGTT
CCAGAGAGGACACGCCGAGCAGATTGTCCAGGATGGGTGCGACACCCACTCCCTTTAAGTCCACAGGGGATATTGCAGGCACAGTTGTCC
CAGAGACCAACAAGGAACCCAGATACCAAGAGGACCCCCCAGCTCCTCAACCAAAAGCAGCCCCGAGAACTTTTCTTCGTCCTAGTCCTG
AAGATGAAGCAATATATGGCCCTAATACCAAAATGGTAAGGTTCAAGAAGGGAGACAGCGTGGGCCTCCGGTTGGCTGGTGGCAATGATG
TCGGGATATTTGTTGCTGGCATTCAAGAAGGGACCTCGGCGGAGCAGGAGGGCCTTCAAGAAGGAGACCAGATTCTGAAGATAACCATGA
TGACTACACAGACTTCTACTATGACATTTGCTCCTTTTGAGGATACATTGAGTTGGATGCTATTTGGCTGGCAGCAGCCGTTTTCATCAT
GTGAGAAGAAAAGTGAAGCAAAGTCACCTTCCAATGGCGTTGGGTCATTGGCCTCAAAGCCGGTAGATGTTGCCTCAGATAATGTTAAAA
AGAAACATACTAAGAAGAATGAATAAATTTACGTGATGAGCTCTACAAGGCCAAAAATTTTTTTTCTTATCTACCTGTTATATTGTGCTA
ATTTTTCTATGTATGTGATGTGAAATGAAGACTATATATATGGAATGGAGGTGACAGAAAGAAAGAAATTCTTTGTTTGAGGGAGACTTC
CCCTTTCTGGATTGTATTTGTAGAGTGTTACGAGTGTATCATGTGATTATGCTTTACCGGTATAAGAGATTCTGTTGTGATTATTTGAAT
AGTTTTATATTAATAAAAGAAGACAAAATTTTTTAAATGTTAGAAAAAGCAGATCTGTCATTGCAAAGTAACAAAAATTTTAAGCTTTTA
AAAATGTAGATTTTTCATATTTTTAAAATTTGAATCTATTTGAGCTTTAGTTCAGCAGAATTAAATTTTTACTTGACATTATCATTAAAA
TTGCTAGGTATGGAGAACAATTCCTATTTTATTTTGAACACTGAGAAGAGTAAACTTTTCCTAAAACACTTTATATTATAAATGAAAATA
AATTGCTAGTTTATATTTTAGATATAAACATCATATTTTTTATTAATACCTACATCAAATGGAAAATATCTGAAATTTTTTTTCCATAGC
AGGTATTTTCTACTAGAAGTAGTTTTACTACTTTTCATTTAGAACAGAGTATGAGTCTTAATCTGAAGTCTTTTTCATGCCCTTGTTTTA
AAAAAACTACTTTTTTTGGCCTCAAAAAAATCAAGGGTGTAATTTTTAATAAATTGTTAATCCTATGTTTTGTAATTTTCATTTTAGGAG
CTTGACTTATTTTTTTCTCTCTCATAAAAACACATTTGTTTTAATTGTAGGAGAAATTTTCTCAGCATTTTGCATGTTCTTTCTAATCTT
TGTTGGTCTGAATATATTGGTAGTAATTACTGTAATTATTCAACAAAAAGCATATCCGTTCAAAAATTTTTCCACTATGTCTTTTTTCTA
GTGGCTACTGTTTTAGTTTTCTAGTTGAATATCTCTGACAAGCTTTCGTATGGTTTTGTTATATTTTCATCTACATGTAATGTGTTATTA
ATTTTATTAAATGAAAACTAATCACCTTCATGTGGAAATGCTCTGAGAATTGTCCTTAGGCATTTGGTAGTAACCAGCTAACCAAGAAGA
AACAGAGAAACCAGAACTTCATATGGCAGTCCATTTAGATGAAGAATGATGATATAAAATCTGGTTCCTTCTTAGCAAAATAAAAAACAA
ACAAGAAAAGATACTAAATGATGTTAATTTTCTTACTTTATGATTTAGAAGTCCAGTTATAATATTAAAACTCTGTGACATAGTTTCTTT
TACCAAAACCATGAACCTACTCCCCGTATCAGGTATTTTCGATGGTTTAGAAGTACTCAAGTCACATCACATTCAAGTTAGAAGTTTTTT
TTTTGTTGTTGTTATTTTAAATTTTTAACAAATATAAACACCAGCAGATACTATTACTTGCTTAAAAAATTGGGAGGGGGCACTTTTCAT
AGTCTTGGAATGCTAAGAAGTTTTATTTTTAATATTGTGACAGAAAGCTTTAAGTATTTAAGAGCTCTGTATTATATTTGATACTCTTAC
AGTTAAAAACTTTTCAAAATTAATACATTGTTAATTATTGACCAGTTTTGAAGTTTGGGTTTAACTGTAGTTGAAATGGAAGGACTCTTG
TTTTACACTTGTATTAAAGATAAATTTATTAAAATAAGTTATTTAGCACCAATGGAGTATTACATTATTTTTATGTTTTATATTTTTCTT
GAGGTAGAGTTTCAGAACTCATCTAGTATTTTGACTAATATAGTATATATTCAGTGATTACTGTTCAAATGGGACATTGGTAGAAACTTT
ATTAATCTATGCAAGTATCCTATAACCCTCAATTCAAGGCTCTTTTGTAAAAAATGTACTGGAGAACATGGCTTAGGCCTGAAACCCATC
CTGAATCTATTCAGGTCACCTGTAGAGTCTTGACTTGGATTTGCAAAGCAGATTGTTAGACTCCTTACCCAATGTGAAGTGTGAATAAGG
CCTATAGGCCTGCCTCACACAGCTAATCAGAGGTGGCACTGAGAAAGTCAAGTCCTAATAGGTCTCCTTAAAAAAAAAAAGGAGACAAAA
AGCTGGCAAGAACATGAGCCAGCTTCCCTCAGTGCTGTCACTCTCAAGTAAAACATGGCCAAATGAATATCAAACTGGTTTATCAGATTA
GTCACTCTTCCTTACTGAGGGAGTATCAAGTAAGGGCTGGAGAGAGACCAGATATGTGGAGTTGTTGGCTTTCAGTGGAAATGGTAGCCT
CCCTGTGGGTAGAGACCAAAAGGTAGAGAGATGACAGAAGGGAGACTCTGATTAGTGTATTTTTTTTTTGTCTATTCCTTAAAGCCCAGA
CACCTTTCCATTAAAATCTACTTCAAATCACAAGTTGATTACAATTGAGTGGAACATCCCATGTTGTAAATGGAATAATGTGTTCAGAAT
GCTCTTTCTTTCCCCCAATAAAGCCCTTTATAGTGTTT

>91068_91068_7_TJP2-TMEM38B_TJP2_chr9_71845148_ENST00000453658_TMEM38B_chr9_108536146_ENST00000374688_length(amino acids)=667AA_BP=596
LRLPPGARAPRTLRSQGSRVRSTTLLSSPCEWDWHPGCSSRSKYSRKHRAVPVHGPRCQAPGMEELIWEQYTVTLQKDSKRGFGIAVSGG
RDNPHFENGETSIVISDVLPGGPADGLLQENDRVVMVNGTPMEDVLHSFAVQQLRKSGKVAAIVVKRPRKVQVAALQASPPLDQDDRAFE
VMDEFDGRSFRSGYSERSRLNSHGGRSRSWEDSPERGRPHERARSRERDLSRDRSRGRSLERGLDQDHARTRDRSRGRSLERGLDHDFGP
SRDRDRDRSRGRSIDQDYERAYHRAYDPDYERAYSPEYRRGARHDARSRGPRSRSREHPHSRSPSPEPRGRPGPIGVLLMKSRANEEYGL
RLGSQIFVKEMTRTGLATKDGNLHEGDIILKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSQQTLINIPSLNDSDSEIEDISEIESN
RSFSPEERRHQYSDYDYHSSSEKLKERPSSREDTPSRLSRMGATPTPFKSTGDIAGTVVPETNKEPRYQEDPPAPQPKAAPRTFLRPSPE
DEAIYGPNTKMVRFKKGDSVGLRLAGGNDVGIFVAGIQEGTSAEQEGLQEGDQILKITMMTTQTSTMTFAPFEDTLSWMLFGWQQPFSSC
EKKSEAKSPSNGVGSLASKPVDVASDNVKKKHTKKNE

--------------------------------------------------------------
>91068_91068_8_TJP2-TMEM38B_TJP2_chr9_71845148_ENST00000453658_TMEM38B_chr9_108536146_ENST00000374692_length(transcript)=4538nt_BP=1790nt
AGCTGCGTCTCCCTCCCGGGGCTCGCGCGCCCAGAACCCTCCGGTCTCAAGGAAGCAGGGTGCGAAGTACCACATTACTGTCATCTCCCT
GTGAGTGGGATTGGCACCCCGGCTGCAGCTCCAGGAGCAAGTACTCCAGGAAGCACAGAGCTGTACCAGTACACGGCCCACGTTGCCAGG
CCCCAGGCATGGAAGAGCTGATATGGGAACAGTACACTGTGACCCTACAAAAGGATTCCAAAAGAGGATTTGGAATTGCAGTGTCCGGAG
GCAGAGACAACCCCCACTTTGAAAATGGAGAAACGTCAATTGTCATTTCTGATGTGCTCCCGGGTGGGCCTGCTGATGGGCTGCTCCAAG
AAAATGACAGAGTGGTCATGGTCAATGGCACCCCCATGGAGGATGTGCTTCATTCGTTTGCAGTTCAGCAGCTCAGAAAAAGTGGGAAGG
TCGCTGCTATTGTGGTCAAGAGGCCCCGGAAGGTCCAGGTGGCCGCACTTCAGGCCAGCCCTCCCCTGGATCAGGATGACCGGGCTTTTG
AGGTGATGGACGAGTTTGATGGCAGAAGTTTCCGGAGTGGCTACAGCGAGAGGAGCCGGCTGAACAGCCATGGGGGGCGCAGCCGCAGCT
GGGAGGACAGCCCGGAAAGGGGGCGTCCCCATGAGCGGGCCCGGAGCCGGGAGCGGGACCTCAGCCGGGACCGGAGCCGTGGCCGGAGCC
TGGAGCGGGGCCTGGACCAAGACCATGCGCGCACCCGAGACCGCAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCACGACTTTGGGC
CATCCCGGGACCGGGACCGTGACCGCAGCCGCGGCCGGAGCATTGACCAGGACTACGAGCGAGCCTATCACCGGGCCTACGACCCAGACT
ACGAGCGGGCCTACAGCCCGGAGTACAGGCGCGGGGCCCGCCACGATGCCCGCTCTCGGGGACCCCGAAGCCGCAGCCGCGAGCACCCGC
ACTCACGGAGCCCCAGCCCCGAGCCTAGGGGGCGGCCGGGGCCCATCGGGGTCCTCCTGATGAAAAGCAGAGCGAACGAAGAGTATGGTC
TCCGGCTTGGGAGTCAGATCTTCGTAAAGGAAATGACCCGAACGGGTCTGGCAACTAAAGATGGCAACCTTCACGAAGGAGACATAATTC
TCAAGATCAATGGGACTGTAACTGAGAACATGTCTTTAACGGATGCTCGAAAATTGATAGAAAAGTCAAGAGGAAAACTACAGCTAGTGG
TGTTGAGAGACAGCCAGCAGACCCTCATCAACATCCCGTCATTAAATGACAGTGACTCAGAAATAGAAGATATTTCAGAAATAGAGTCAA
ACCGATCATTTTCTCCAGAGGAGAGACGTCATCAGTATTCTGATTATGATTATCATTCCTCAAGTGAGAAGCTGAAGGAAAGGCCAAGTT
CCAGAGAGGACACGCCGAGCAGATTGTCCAGGATGGGTGCGACACCCACTCCCTTTAAGTCCACAGGGGATATTGCAGGCACAGTTGTCC
CAGAGACCAACAAGGAACCCAGATACCAAGAGGACCCCCCAGCTCCTCAACCAAAAGCAGCCCCGAGAACTTTTCTTCGTCCTAGTCCTG
AAGATGAAGCAATATATGGCCCTAATACCAAAATGGTAAGGTTCAAGAAGGGAGACAGCGTGGGCCTCCGGTTGGCTGGTGGCAATGATG
TCGGGATATTTGTTGCTGGCATTCAAGAAGGGACCTCGGCGGAGCAGGAGGGCCTTCAAGAAGGAGACCAGATTCTGAAGATAACCATGA
TGACTACACAGACTTCTACTATGACATTTGCTCCTTTTGAGGATACATTGAGTTGGATGCTATTTGGCTGGCAGCAGCCGTTTTCATCAT
GTGAGAAGAAAAGTGAAGCAAAGTCACCTTCCAATGGCGTTGGGTCATTGGCCTCAAAGCCGGTAGATGTTGCCTCAGATAATGTTAAAA
AGAAACATACTAAGAAGAATGAATAAATTTACGTGATGAGCTCTACAAGGCCAAAAATTTTTTTTCTTATCTACCTGTTATATTGTGCTA
ATTTTTCTATGTATGTGATGTGAAATGAAGACTATATATATGGAATGGAGGTGACAGAAAGAAAGAAATTCTTTGTTTGAGGGAGACTTC
CCCTTTCTGGATTGTATTTGTAGAGTGTTACGAGTGTATCATGTGATTATGCTTTACCGGTATAAGAGATTCTGTTGTGATTATTTGAAT
AGTTTTATATTAATAAAAGAAGACAAAATTTTTTAAATGTTAGAAAAAGCAGATCTGTCATTGCAAAGTAACAAAAATTTTAAGCTTTTA
AAAATGTAGATTTTTCATATTTTTAAAATTTGAATCTATTTGAGCTTTAGTTCAGCAGAATTAAATTTTTACTTGACATTATCATTAAAA
TTGCTAGGTATGGAGAACAATTCCTATTTTATTTTGAACACTGAGAAGAGTAAACTTTTCCTAAAACACTTTATATTATAAATGAAAATA
AATTGCTAGTTTATATTTTAGATATAAACATCATATTTTTTATTAATACCTACATCAAATGGAAAATATCTGAAATTTTTTTTCCATAGC
AGGTATTTTCTACTAGAAGTAGTTTTACTACTTTTCATTTAGAACAGAGTATGAGTCTTAATCTGAAGTCTTTTTCATGCCCTTGTTTTA
AAAAAACTACTTTTTTTGGCCTCAAAAAAATCAAGGGTGTAATTTTTAATAAATTGTTAATCCTATGTTTTGTAATTTTCATTTTAGGAG
CTTGACTTATTTTTTTCTCTCTCATAAAAACACATTTGTTTTAATTGTAGGAGAAATTTTCTCAGCATTTTGCATGTTCTTTCTAATCTT
TGTTGGTCTGAATATATTGGTAGTAATTACTGTAATTATTCAACAAAAAGCATATCCGTTCAAAAATTTTTCCACTATGTCTTTTTTCTA
GTGGCTACTGTTTTAGTTTTCTAGTTGAATATCTCTGACAAGCTTTCGTATGGTTTTGTTATATTTTCATCTACATGTAATGTGTTATTA
ATTTTATTAAATGAAAACTAATCACCTTCATGTGGAAATGCTCTGAGAATTGTCCTTAGGCATTTGGTAGTAACCAGCTAACCAAGAAGA
AACAGAGAAACCAGAACTTCATATGGCAGTCCATTTAGATGAAGAATGATGATATAAAATCTGGTTCCTTCTTAGCAAAATAAAAAACAA
ACAAGAAAAGATACTAAATGATGTTAATTTTCTTACTTTATGATTTAGAAGTCCAGTTATAATATTAAAACTCTGTGACATAGTTTCTTT
TACCAAAACCATGAACCTACTCCCCGTATCAGGTATTTTCGATGGTTTAGAAGTACTCAAGTCACATCACATTCAAGTTAGAAGTTTTTT
TTTTGTTGTTGTTATTTTAAATTTTTAACAAATATAAACACCAGCAGATACTATTACTTGCTTAAAAAATTGGGAGGGGGCACTTTTCAT
AGTCTTGGAATGCTAAGAAGTTTTATTTTTAATATTGTGACAGAAAGCTTTAAGTATTTAAGAGCTCTGTATTATATTTGATACTCTTAC
AGTTAAAAACTTTTCAAAATTAATACATTGTTAATTATTGACCAGTTTTGAAGTTTGGGTTTAACTGTAGTTGAAATGGAAGGACTCTTG
TTTTACACTTGTATTAAAGATAAATTTATTAAAATAAGTTATTTAGCACCAATGGAGTATTACATTATTTTTATGTTTTATATTTTTCTT
GAGGTAGAGTTTCAGAACTCATCTAGTATTTTGACTAATATAGTATATATTCAGTGATTACTGTTCAAATGGGACATTGGTAGAAACTTT
ATTAATCTATGCAAGTATCCTATAACCCTCAATTCAAGGCTCTTTTGTAAAAAATGTACTGGAGAACATGGCTTAGGCCTGAAACCCATC
CTGAATCTATTCAGGTCACCTGTAGAGTCTTGACTTGGATTTGCAAAGCAGATTGTTAGACTCCTTACCCAATGTGAAGTGTGAATAAGG
CCTATAGGCCTGCCTCACACAGCTAATCAGAGGTGGCACTGAGAAAGTCAAGTCCTAATAGGTCTCCTTAAAAAAAAAAAGGAGACAAAA
AGCTGGCAAGAACATGAGCCAGCTTCCCTCAGTGCTGTCACTCTCAAGTAAAACATGGCCAAATGAATATCAAACTGGTTTATCAGATTA
GTCACTCTTCCTTACTGAGGGAGTATCAAGTAAGGGCTGGAGAGAGACCAGATATGTGGAGTTGTTGGCTTTCAGTGGAAATGGTAGCCT
CCCTGTGGGTAGAGACCAAAAGGTAGAGAGATGACAGAAGGGAGACTCTGATTAGTGTATTTTTTTTTTGTCTATTCCTTAAAGCCCAGA
CACCTTTCCATTAAAATCTACTTCAAATCACAAGTTGATTACAATTGAGTGGAACATCCCATGTTGTAAATGGAATAATGTGTTCAGAAT
GCTCTTTCTTTCCCCCAATAAAGCCCTTTATAGTGTTT

>91068_91068_8_TJP2-TMEM38B_TJP2_chr9_71845148_ENST00000453658_TMEM38B_chr9_108536146_ENST00000374692_length(amino acids)=667AA_BP=596
LRLPPGARAPRTLRSQGSRVRSTTLLSSPCEWDWHPGCSSRSKYSRKHRAVPVHGPRCQAPGMEELIWEQYTVTLQKDSKRGFGIAVSGG
RDNPHFENGETSIVISDVLPGGPADGLLQENDRVVMVNGTPMEDVLHSFAVQQLRKSGKVAAIVVKRPRKVQVAALQASPPLDQDDRAFE
VMDEFDGRSFRSGYSERSRLNSHGGRSRSWEDSPERGRPHERARSRERDLSRDRSRGRSLERGLDQDHARTRDRSRGRSLERGLDHDFGP
SRDRDRDRSRGRSIDQDYERAYHRAYDPDYERAYSPEYRRGARHDARSRGPRSRSREHPHSRSPSPEPRGRPGPIGVLLMKSRANEEYGL
RLGSQIFVKEMTRTGLATKDGNLHEGDIILKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSQQTLINIPSLNDSDSEIEDISEIESN
RSFSPEERRHQYSDYDYHSSSEKLKERPSSREDTPSRLSRMGATPTPFKSTGDIAGTVVPETNKEPRYQEDPPAPQPKAAPRTFLRPSPE
DEAIYGPNTKMVRFKKGDSVGLRLAGGNDVGIFVAGIQEGTSAEQEGLQEGDQILKITMMTTQTSTMTFAPFEDTLSWMLFGWQQPFSSC
EKKSEAKSPSNGVGSLASKPVDVASDNVKKKHTKKNE

--------------------------------------------------------------
>91068_91068_9_TJP2-TMEM38B_TJP2_chr9_71845148_ENST00000535702_TMEM38B_chr9_108536146_ENST00000374688_length(transcript)=4582nt_BP=1834nt
ATATGGATGTGTCACTGTGTGAGATGACAACAGGATTTGCTGGAAATGTGGGCCACTATTGTATCCGCCTTACGTAACCACATGGAGTGA
TGGAAATGGGTGAGCAGCCCGGAATGTAGGCGGTGGCCTGGCCCATGCATCTCCAGAGACCATGAAGACTGCTCAAGCCCTACATAGGAT
GTGGATCCAGGCTGTTAAAAAGTTGAGGAGATGGAAAGGCCGTGCCCCAGGCATGGAAGAGCTGATATGGGAACAGTACACTGTGACCCT
ACAAAAGGATTCCAAAAGAGGATTTGGAATTGCAGTGTCCGGAGGCAGAGACAACCCCCACTTTGAAAATGGAGAAACGTCAATTGTCAT
TTCTGATGTGCTCCCGGGTGGGCCTGCTGATGGGCTGCTCCAAGAAAATGACAGAGTGGTCATGGTCAATGGCACCCCCATGGAGGATGT
GCTTCATTCGTTTGCAGTTCAGCAGCTCAGAAAAAGTGGGAAGGTCGCTGCTATTGTGGTCAAGAGGCCCCGGAAGGTCCAGGTGGCCGC
ACTTCAGGCCAGCCCTCCCCTGGATCAGGATGACCGGGCTTTTGAGGTGATGGACGAGTTTGATGGCAGAAGTTTCCGGAGTGGCTACAG
CGAGAGGAGCCGGCTGAACAGCCATGGGGGGCGCAGCCGCAGCTGGGAGGACAGCCCGGAAAGGGGGCGTCCCCATGAGCGGGCCCGGAG
CCGGGAGCGGGACCTCAGCCGGGACCGGAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCAAGACCATGCGCGCACCCGAGACCGCAG
CCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCACGACTTTGGGCCATCCCGGGACCGGGACCGTGACCGCAGCCGCGGCCGGAGCATTGA
CCAGGACTACGAGCGAGCCTATCACCGGGCCTACGACCCAGACTACGAGCGGGCCTACAGCCCGGAGTACAGGCGCGGGGCCCGCCACGA
TGCCCGCTCTCGGGGACCCCGAAGCCGCAGCCGCGAGCACCCGCACTCACGGAGCCCCAGCCCCGAGCCTAGGGGGCGGCCGGGGCCCAT
CGGGGTCCTCCTGATGAAAAGCAGAGCGAACGAAGAGTATGGTCTCCGGCTTGGGAGTCAGATCTTCGTAAAGGAAATGACCCGAACGGG
TCTGGCAACTAAAGATGGCAACCTTCACGAAGGAGACATAATTCTCAAGATCAATGGGACTGTAACTGAGAACATGTCTTTAACGGATGC
TCGAAAATTGATAGAAAAGTCAAGAGGAAAACTACAGCTAGTGGTGTTGAGAGACAGCCAGCAGACCCTCATCAACATCCCGTCATTAAA
TGACAGTGACTCAGAAATAGAAGATATTTCAGAAATAGAGTCAAACCGATCATTTTCTCCAGAGGAGAGACGTCATCAGTATTCTGATTA
TGATTATCATTCCTCAAGTGAGAAGCTGAAGGAAAGGCCAAGTTCCAGAGAGGACACGCCGAGCAGATTGTCCAGGATGGGTGCGACACC
CACTCCCTTTAAGTCCACAGGGGATATTGCAGGCACAGTTGTCCCAGAGACCAACAAGGAACCCAGATACCAAGAGGACCCCCCAGCTCC
TCAACCAAAAGCAGCCCCGAGAACTTTTCTTCGTCCTAGTCCTGAAGATGAAGCAATATATGGCCCTAATACCAAAATGGTAAGGTTCAA
GAAGGGAGACAGCGTGGGCCTCCGGTTGGCTGGTGGCAATGATGTCGGGATATTTGTTGCTGGCATTCAAGAAGGGACCTCGGCGGAGCA
GGAGGGCCTTCAAGAAGGAGACCAGATTCTGAAGATAACCATGATGACTACACAGACTTCTACTATGACATTTGCTCCTTTTGAGGATAC
ATTGAGTTGGATGCTATTTGGCTGGCAGCAGCCGTTTTCATCATGTGAGAAGAAAAGTGAAGCAAAGTCACCTTCCAATGGCGTTGGGTC
ATTGGCCTCAAAGCCGGTAGATGTTGCCTCAGATAATGTTAAAAAGAAACATACTAAGAAGAATGAATAAATTTACGTGATGAGCTCTAC
AAGGCCAAAAATTTTTTTTCTTATCTACCTGTTATATTGTGCTAATTTTTCTATGTATGTGATGTGAAATGAAGACTATATATATGGAAT
GGAGGTGACAGAAAGAAAGAAATTCTTTGTTTGAGGGAGACTTCCCCTTTCTGGATTGTATTTGTAGAGTGTTACGAGTGTATCATGTGA
TTATGCTTTACCGGTATAAGAGATTCTGTTGTGATTATTTGAATAGTTTTATATTAATAAAAGAAGACAAAATTTTTTAAATGTTAGAAA
AAGCAGATCTGTCATTGCAAAGTAACAAAAATTTTAAGCTTTTAAAAATGTAGATTTTTCATATTTTTAAAATTTGAATCTATTTGAGCT
TTAGTTCAGCAGAATTAAATTTTTACTTGACATTATCATTAAAATTGCTAGGTATGGAGAACAATTCCTATTTTATTTTGAACACTGAGA
AGAGTAAACTTTTCCTAAAACACTTTATATTATAAATGAAAATAAATTGCTAGTTTATATTTTAGATATAAACATCATATTTTTTATTAA
TACCTACATCAAATGGAAAATATCTGAAATTTTTTTTCCATAGCAGGTATTTTCTACTAGAAGTAGTTTTACTACTTTTCATTTAGAACA
GAGTATGAGTCTTAATCTGAAGTCTTTTTCATGCCCTTGTTTTAAAAAAACTACTTTTTTTGGCCTCAAAAAAATCAAGGGTGTAATTTT
TAATAAATTGTTAATCCTATGTTTTGTAATTTTCATTTTAGGAGCTTGACTTATTTTTTTCTCTCTCATAAAAACACATTTGTTTTAATT
GTAGGAGAAATTTTCTCAGCATTTTGCATGTTCTTTCTAATCTTTGTTGGTCTGAATATATTGGTAGTAATTACTGTAATTATTCAACAA
AAAGCATATCCGTTCAAAAATTTTTCCACTATGTCTTTTTTCTAGTGGCTACTGTTTTAGTTTTCTAGTTGAATATCTCTGACAAGCTTT
CGTATGGTTTTGTTATATTTTCATCTACATGTAATGTGTTATTAATTTTATTAAATGAAAACTAATCACCTTCATGTGGAAATGCTCTGA
GAATTGTCCTTAGGCATTTGGTAGTAACCAGCTAACCAAGAAGAAACAGAGAAACCAGAACTTCATATGGCAGTCCATTTAGATGAAGAA
TGATGATATAAAATCTGGTTCCTTCTTAGCAAAATAAAAAACAAACAAGAAAAGATACTAAATGATGTTAATTTTCTTACTTTATGATTT
AGAAGTCCAGTTATAATATTAAAACTCTGTGACATAGTTTCTTTTACCAAAACCATGAACCTACTCCCCGTATCAGGTATTTTCGATGGT
TTAGAAGTACTCAAGTCACATCACATTCAAGTTAGAAGTTTTTTTTTTGTTGTTGTTATTTTAAATTTTTAACAAATATAAACACCAGCA
GATACTATTACTTGCTTAAAAAATTGGGAGGGGGCACTTTTCATAGTCTTGGAATGCTAAGAAGTTTTATTTTTAATATTGTGACAGAAA
GCTTTAAGTATTTAAGAGCTCTGTATTATATTTGATACTCTTACAGTTAAAAACTTTTCAAAATTAATACATTGTTAATTATTGACCAGT
TTTGAAGTTTGGGTTTAACTGTAGTTGAAATGGAAGGACTCTTGTTTTACACTTGTATTAAAGATAAATTTATTAAAATAAGTTATTTAG
CACCAATGGAGTATTACATTATTTTTATGTTTTATATTTTTCTTGAGGTAGAGTTTCAGAACTCATCTAGTATTTTGACTAATATAGTAT
ATATTCAGTGATTACTGTTCAAATGGGACATTGGTAGAAACTTTATTAATCTATGCAAGTATCCTATAACCCTCAATTCAAGGCTCTTTT
GTAAAAAATGTACTGGAGAACATGGCTTAGGCCTGAAACCCATCCTGAATCTATTCAGGTCACCTGTAGAGTCTTGACTTGGATTTGCAA
AGCAGATTGTTAGACTCCTTACCCAATGTGAAGTGTGAATAAGGCCTATAGGCCTGCCTCACACAGCTAATCAGAGGTGGCACTGAGAAA
GTCAAGTCCTAATAGGTCTCCTTAAAAAAAAAAAGGAGACAAAAAGCTGGCAAGAACATGAGCCAGCTTCCCTCAGTGCTGTCACTCTCA
AGTAAAACATGGCCAAATGAATATCAAACTGGTTTATCAGATTAGTCACTCTTCCTTACTGAGGGAGTATCAAGTAAGGGCTGGAGAGAG
ACCAGATATGTGGAGTTGTTGGCTTTCAGTGGAAATGGTAGCCTCCCTGTGGGTAGAGACCAAAAGGTAGAGAGATGACAGAAGGGAGAC
TCTGATTAGTGTATTTTTTTTTTGTCTATTCCTTAAAGCCCAGACACCTTTCCATTAAAATCTACTTCAAATCACAAGTTGATTACAATT
GAGTGGAACATCCCATGTTGTAAATGGAATAATGTGTTCAGAATGCTCTTTCTTTCCCCCAATAAAGCCCTTTATAGTGTTT

>91068_91068_9_TJP2-TMEM38B_TJP2_chr9_71845148_ENST00000535702_TMEM38B_chr9_108536146_ENST00000374688_length(amino acids)=640AA_BP=569
MAHASPETMKTAQALHRMWIQAVKKLRRWKGRAPGMEELIWEQYTVTLQKDSKRGFGIAVSGGRDNPHFENGETSIVISDVLPGGPADGL
LQENDRVVMVNGTPMEDVLHSFAVQQLRKSGKVAAIVVKRPRKVQVAALQASPPLDQDDRAFEVMDEFDGRSFRSGYSERSRLNSHGGRS
RSWEDSPERGRPHERARSRERDLSRDRSRGRSLERGLDQDHARTRDRSRGRSLERGLDHDFGPSRDRDRDRSRGRSIDQDYERAYHRAYD
PDYERAYSPEYRRGARHDARSRGPRSRSREHPHSRSPSPEPRGRPGPIGVLLMKSRANEEYGLRLGSQIFVKEMTRTGLATKDGNLHEGD
IILKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSQQTLINIPSLNDSDSEIEDISEIESNRSFSPEERRHQYSDYDYHSSSEKLKER
PSSREDTPSRLSRMGATPTPFKSTGDIAGTVVPETNKEPRYQEDPPAPQPKAAPRTFLRPSPEDEAIYGPNTKMVRFKKGDSVGLRLAGG
NDVGIFVAGIQEGTSAEQEGLQEGDQILKITMMTTQTSTMTFAPFEDTLSWMLFGWQQPFSSCEKKSEAKSPSNGVGSLASKPVDVASDN
VKKKHTKKNE

--------------------------------------------------------------
>91068_91068_10_TJP2-TMEM38B_TJP2_chr9_71845148_ENST00000535702_TMEM38B_chr9_108536146_ENST00000374692_length(transcript)=4582nt_BP=1834nt
ATATGGATGTGTCACTGTGTGAGATGACAACAGGATTTGCTGGAAATGTGGGCCACTATTGTATCCGCCTTACGTAACCACATGGAGTGA
TGGAAATGGGTGAGCAGCCCGGAATGTAGGCGGTGGCCTGGCCCATGCATCTCCAGAGACCATGAAGACTGCTCAAGCCCTACATAGGAT
GTGGATCCAGGCTGTTAAAAAGTTGAGGAGATGGAAAGGCCGTGCCCCAGGCATGGAAGAGCTGATATGGGAACAGTACACTGTGACCCT
ACAAAAGGATTCCAAAAGAGGATTTGGAATTGCAGTGTCCGGAGGCAGAGACAACCCCCACTTTGAAAATGGAGAAACGTCAATTGTCAT
TTCTGATGTGCTCCCGGGTGGGCCTGCTGATGGGCTGCTCCAAGAAAATGACAGAGTGGTCATGGTCAATGGCACCCCCATGGAGGATGT
GCTTCATTCGTTTGCAGTTCAGCAGCTCAGAAAAAGTGGGAAGGTCGCTGCTATTGTGGTCAAGAGGCCCCGGAAGGTCCAGGTGGCCGC
ACTTCAGGCCAGCCCTCCCCTGGATCAGGATGACCGGGCTTTTGAGGTGATGGACGAGTTTGATGGCAGAAGTTTCCGGAGTGGCTACAG
CGAGAGGAGCCGGCTGAACAGCCATGGGGGGCGCAGCCGCAGCTGGGAGGACAGCCCGGAAAGGGGGCGTCCCCATGAGCGGGCCCGGAG
CCGGGAGCGGGACCTCAGCCGGGACCGGAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCAAGACCATGCGCGCACCCGAGACCGCAG
CCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCACGACTTTGGGCCATCCCGGGACCGGGACCGTGACCGCAGCCGCGGCCGGAGCATTGA
CCAGGACTACGAGCGAGCCTATCACCGGGCCTACGACCCAGACTACGAGCGGGCCTACAGCCCGGAGTACAGGCGCGGGGCCCGCCACGA
TGCCCGCTCTCGGGGACCCCGAAGCCGCAGCCGCGAGCACCCGCACTCACGGAGCCCCAGCCCCGAGCCTAGGGGGCGGCCGGGGCCCAT
CGGGGTCCTCCTGATGAAAAGCAGAGCGAACGAAGAGTATGGTCTCCGGCTTGGGAGTCAGATCTTCGTAAAGGAAATGACCCGAACGGG
TCTGGCAACTAAAGATGGCAACCTTCACGAAGGAGACATAATTCTCAAGATCAATGGGACTGTAACTGAGAACATGTCTTTAACGGATGC
TCGAAAATTGATAGAAAAGTCAAGAGGAAAACTACAGCTAGTGGTGTTGAGAGACAGCCAGCAGACCCTCATCAACATCCCGTCATTAAA
TGACAGTGACTCAGAAATAGAAGATATTTCAGAAATAGAGTCAAACCGATCATTTTCTCCAGAGGAGAGACGTCATCAGTATTCTGATTA
TGATTATCATTCCTCAAGTGAGAAGCTGAAGGAAAGGCCAAGTTCCAGAGAGGACACGCCGAGCAGATTGTCCAGGATGGGTGCGACACC
CACTCCCTTTAAGTCCACAGGGGATATTGCAGGCACAGTTGTCCCAGAGACCAACAAGGAACCCAGATACCAAGAGGACCCCCCAGCTCC
TCAACCAAAAGCAGCCCCGAGAACTTTTCTTCGTCCTAGTCCTGAAGATGAAGCAATATATGGCCCTAATACCAAAATGGTAAGGTTCAA
GAAGGGAGACAGCGTGGGCCTCCGGTTGGCTGGTGGCAATGATGTCGGGATATTTGTTGCTGGCATTCAAGAAGGGACCTCGGCGGAGCA
GGAGGGCCTTCAAGAAGGAGACCAGATTCTGAAGATAACCATGATGACTACACAGACTTCTACTATGACATTTGCTCCTTTTGAGGATAC
ATTGAGTTGGATGCTATTTGGCTGGCAGCAGCCGTTTTCATCATGTGAGAAGAAAAGTGAAGCAAAGTCACCTTCCAATGGCGTTGGGTC
ATTGGCCTCAAAGCCGGTAGATGTTGCCTCAGATAATGTTAAAAAGAAACATACTAAGAAGAATGAATAAATTTACGTGATGAGCTCTAC
AAGGCCAAAAATTTTTTTTCTTATCTACCTGTTATATTGTGCTAATTTTTCTATGTATGTGATGTGAAATGAAGACTATATATATGGAAT
GGAGGTGACAGAAAGAAAGAAATTCTTTGTTTGAGGGAGACTTCCCCTTTCTGGATTGTATTTGTAGAGTGTTACGAGTGTATCATGTGA
TTATGCTTTACCGGTATAAGAGATTCTGTTGTGATTATTTGAATAGTTTTATATTAATAAAAGAAGACAAAATTTTTTAAATGTTAGAAA
AAGCAGATCTGTCATTGCAAAGTAACAAAAATTTTAAGCTTTTAAAAATGTAGATTTTTCATATTTTTAAAATTTGAATCTATTTGAGCT
TTAGTTCAGCAGAATTAAATTTTTACTTGACATTATCATTAAAATTGCTAGGTATGGAGAACAATTCCTATTTTATTTTGAACACTGAGA
AGAGTAAACTTTTCCTAAAACACTTTATATTATAAATGAAAATAAATTGCTAGTTTATATTTTAGATATAAACATCATATTTTTTATTAA
TACCTACATCAAATGGAAAATATCTGAAATTTTTTTTCCATAGCAGGTATTTTCTACTAGAAGTAGTTTTACTACTTTTCATTTAGAACA
GAGTATGAGTCTTAATCTGAAGTCTTTTTCATGCCCTTGTTTTAAAAAAACTACTTTTTTTGGCCTCAAAAAAATCAAGGGTGTAATTTT
TAATAAATTGTTAATCCTATGTTTTGTAATTTTCATTTTAGGAGCTTGACTTATTTTTTTCTCTCTCATAAAAACACATTTGTTTTAATT
GTAGGAGAAATTTTCTCAGCATTTTGCATGTTCTTTCTAATCTTTGTTGGTCTGAATATATTGGTAGTAATTACTGTAATTATTCAACAA
AAAGCATATCCGTTCAAAAATTTTTCCACTATGTCTTTTTTCTAGTGGCTACTGTTTTAGTTTTCTAGTTGAATATCTCTGACAAGCTTT
CGTATGGTTTTGTTATATTTTCATCTACATGTAATGTGTTATTAATTTTATTAAATGAAAACTAATCACCTTCATGTGGAAATGCTCTGA
GAATTGTCCTTAGGCATTTGGTAGTAACCAGCTAACCAAGAAGAAACAGAGAAACCAGAACTTCATATGGCAGTCCATTTAGATGAAGAA
TGATGATATAAAATCTGGTTCCTTCTTAGCAAAATAAAAAACAAACAAGAAAAGATACTAAATGATGTTAATTTTCTTACTTTATGATTT
AGAAGTCCAGTTATAATATTAAAACTCTGTGACATAGTTTCTTTTACCAAAACCATGAACCTACTCCCCGTATCAGGTATTTTCGATGGT
TTAGAAGTACTCAAGTCACATCACATTCAAGTTAGAAGTTTTTTTTTTGTTGTTGTTATTTTAAATTTTTAACAAATATAAACACCAGCA
GATACTATTACTTGCTTAAAAAATTGGGAGGGGGCACTTTTCATAGTCTTGGAATGCTAAGAAGTTTTATTTTTAATATTGTGACAGAAA
GCTTTAAGTATTTAAGAGCTCTGTATTATATTTGATACTCTTACAGTTAAAAACTTTTCAAAATTAATACATTGTTAATTATTGACCAGT
TTTGAAGTTTGGGTTTAACTGTAGTTGAAATGGAAGGACTCTTGTTTTACACTTGTATTAAAGATAAATTTATTAAAATAAGTTATTTAG
CACCAATGGAGTATTACATTATTTTTATGTTTTATATTTTTCTTGAGGTAGAGTTTCAGAACTCATCTAGTATTTTGACTAATATAGTAT
ATATTCAGTGATTACTGTTCAAATGGGACATTGGTAGAAACTTTATTAATCTATGCAAGTATCCTATAACCCTCAATTCAAGGCTCTTTT
GTAAAAAATGTACTGGAGAACATGGCTTAGGCCTGAAACCCATCCTGAATCTATTCAGGTCACCTGTAGAGTCTTGACTTGGATTTGCAA
AGCAGATTGTTAGACTCCTTACCCAATGTGAAGTGTGAATAAGGCCTATAGGCCTGCCTCACACAGCTAATCAGAGGTGGCACTGAGAAA
GTCAAGTCCTAATAGGTCTCCTTAAAAAAAAAAAGGAGACAAAAAGCTGGCAAGAACATGAGCCAGCTTCCCTCAGTGCTGTCACTCTCA
AGTAAAACATGGCCAAATGAATATCAAACTGGTTTATCAGATTAGTCACTCTTCCTTACTGAGGGAGTATCAAGTAAGGGCTGGAGAGAG
ACCAGATATGTGGAGTTGTTGGCTTTCAGTGGAAATGGTAGCCTCCCTGTGGGTAGAGACCAAAAGGTAGAGAGATGACAGAAGGGAGAC
TCTGATTAGTGTATTTTTTTTTTGTCTATTCCTTAAAGCCCAGACACCTTTCCATTAAAATCTACTTCAAATCACAAGTTGATTACAATT
GAGTGGAACATCCCATGTTGTAAATGGAATAATGTGTTCAGAATGCTCTTTCTTTCCCCCAATAAAGCCCTTTATAGTGTTT

>91068_91068_10_TJP2-TMEM38B_TJP2_chr9_71845148_ENST00000535702_TMEM38B_chr9_108536146_ENST00000374692_length(amino acids)=640AA_BP=569
MAHASPETMKTAQALHRMWIQAVKKLRRWKGRAPGMEELIWEQYTVTLQKDSKRGFGIAVSGGRDNPHFENGETSIVISDVLPGGPADGL
LQENDRVVMVNGTPMEDVLHSFAVQQLRKSGKVAAIVVKRPRKVQVAALQASPPLDQDDRAFEVMDEFDGRSFRSGYSERSRLNSHGGRS
RSWEDSPERGRPHERARSRERDLSRDRSRGRSLERGLDQDHARTRDRSRGRSLERGLDHDFGPSRDRDRDRSRGRSIDQDYERAYHRAYD
PDYERAYSPEYRRGARHDARSRGPRSRSREHPHSRSPSPEPRGRPGPIGVLLMKSRANEEYGLRLGSQIFVKEMTRTGLATKDGNLHEGD
IILKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSQQTLINIPSLNDSDSEIEDISEIESNRSFSPEERRHQYSDYDYHSSSEKLKER
PSSREDTPSRLSRMGATPTPFKSTGDIAGTVVPETNKEPRYQEDPPAPQPKAAPRTFLRPSPEDEAIYGPNTKMVRFKKGDSVGLRLAGG
NDVGIFVAGIQEGTSAEQEGLQEGDQILKITMMTTQTSTMTFAPFEDTLSWMLFGWQQPFSSCEKKSEAKSPSNGVGSLASKPVDVASDN
VKKKHTKKNE

--------------------------------------------------------------
>91068_91068_11_TJP2-TMEM38B_TJP2_chr9_71845148_ENST00000539225_TMEM38B_chr9_108536146_ENST00000374688_length(transcript)=4512nt_BP=1764nt
ATGAAGACTGCTCAAGCCCTACATAGGATGTGGATCCAGGCTGTTAAAAAGTTGAGGAGATGGAAAGGCCGTGTGAGTCCCTCTGCAAGC
TCTCCCCTTGTTTTCCCCAACCTTTCTTCATGGGAAGGGGAGGGAAGCAAAACCATTCTCACAGCCCCAGGCATGGAAGAGCTGATATGG
GAACAGTACACTGTGACCCTACAAAAGGATTCCAAAAGAGGATTTGGAATTGCAGTGTCCGGAGGCAGAGACAACCCCCACTTTGAAAAT
GGAGAAACGTCAATTGTCATTTCTGATGTGCTCCCGGGTGGGCCTGCTGATGGGCTGCTCCAAGAAAATGACAGAGTGGTCATGGTCAAT
GGCACCCCCATGGAGGATGTGCTTCATTCGTTTGCAGTTCAGCAGCTCAGAAAAAGTGGGAAGGTCGCTGCTATTGTGGTCAAGAGGCCC
CGGAAGGTCCAGGTGGCCGCACTTCAGGCCAGCCCTCCCCTGGATCAGGATGACCGGGCTTTTGAGGTGATGGACGAGTTTGATGGCAGA
AGTTTCCGGAGTGGCTACAGCGAGAGGAGCCGGCTGAACAGCCATGGGGGGCGCAGCCGCAGCTGGGAGGACAGCCCGGAAAGGGGGCGT
CCCCATGAGCGGGCCCGGAGCCGGGAGCGGGACCTCAGCCGGGACCGGAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCAAGACCAT
GCGCGCACCCGAGACCGCAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCACGACTTTGGGCCATCCCGGGACCGGGACCGTGACCGC
AGCCGCGGCCGGAGCATTGACCAGGACTACGAGCGAGCCTATCACCGGGCCTACGACCCAGACTACGAGCGGGCCTACAGCCCGGAGTAC
AGGCGCGGGGCCCGCCACGATGCCCGCTCTCGGGGACCCCGAAGCCGCAGCCGCGAGCACCCGCACTCACGGAGCCCCAGCCCCGAGCCT
AGGGGGCGGCCGGGGCCCATCGGGGTCCTCCTGATGAAAAGCAGAGCGAACGAAGAGTATGGTCTCCGGCTTGGGAGTCAGATCTTCGTA
AAGGAAATGACCCGAACGGGTCTGGCAACTAAAGATGGCAACCTTCACGAAGGAGACATAATTCTCAAGATCAATGGGACTGTAACTGAG
AACATGTCTTTAACGGATGCTCGAAAATTGATAGAAAAGTCAAGAGGAAAACTACAGCTAGTGGTGTTGAGAGACAGCCAGCAGACCCTC
ATCAACATCCCGTCATTAAATGACAGTGACTCAGAAATAGAAGATATTTCAGAAATAGAGTCAAACCGATCATTTTCTCCAGAGGAGAGA
CGTCATCAGTATTCTGATTATGATTATCATTCCTCAAGTGAGAAGCTGAAGGAAAGGCCAAGTTCCAGAGAGGACACGCCGAGCAGATTG
TCCAGGATGGGTGCGACACCCACTCCCTTTAAGTCCACAGGGGATATTGCAGGCACAGTTGTCCCAGAGACCAACAAGGAACCCAGATAC
CAAGAGGACCCCCCAGCTCCTCAACCAAAAGCAGCCCCGAGAACTTTTCTTCGTCCTAGTCCTGAAGATGAAGCAATATATGGCCCTAAT
ACCAAAATGGTAAGGTTCAAGAAGGGAGACAGCGTGGGCCTCCGGTTGGCTGGTGGCAATGATGTCGGGATATTTGTTGCTGGCATTCAA
GAAGGGACCTCGGCGGAGCAGGAGGGCCTTCAAGAAGGAGACCAGATTCTGAAGATAACCATGATGACTACACAGACTTCTACTATGACA
TTTGCTCCTTTTGAGGATACATTGAGTTGGATGCTATTTGGCTGGCAGCAGCCGTTTTCATCATGTGAGAAGAAAAGTGAAGCAAAGTCA
CCTTCCAATGGCGTTGGGTCATTGGCCTCAAAGCCGGTAGATGTTGCCTCAGATAATGTTAAAAAGAAACATACTAAGAAGAATGAATAA
ATTTACGTGATGAGCTCTACAAGGCCAAAAATTTTTTTTCTTATCTACCTGTTATATTGTGCTAATTTTTCTATGTATGTGATGTGAAAT
GAAGACTATATATATGGAATGGAGGTGACAGAAAGAAAGAAATTCTTTGTTTGAGGGAGACTTCCCCTTTCTGGATTGTATTTGTAGAGT
GTTACGAGTGTATCATGTGATTATGCTTTACCGGTATAAGAGATTCTGTTGTGATTATTTGAATAGTTTTATATTAATAAAAGAAGACAA
AATTTTTTAAATGTTAGAAAAAGCAGATCTGTCATTGCAAAGTAACAAAAATTTTAAGCTTTTAAAAATGTAGATTTTTCATATTTTTAA
AATTTGAATCTATTTGAGCTTTAGTTCAGCAGAATTAAATTTTTACTTGACATTATCATTAAAATTGCTAGGTATGGAGAACAATTCCTA
TTTTATTTTGAACACTGAGAAGAGTAAACTTTTCCTAAAACACTTTATATTATAAATGAAAATAAATTGCTAGTTTATATTTTAGATATA
AACATCATATTTTTTATTAATACCTACATCAAATGGAAAATATCTGAAATTTTTTTTCCATAGCAGGTATTTTCTACTAGAAGTAGTTTT
ACTACTTTTCATTTAGAACAGAGTATGAGTCTTAATCTGAAGTCTTTTTCATGCCCTTGTTTTAAAAAAACTACTTTTTTTGGCCTCAAA
AAAATCAAGGGTGTAATTTTTAATAAATTGTTAATCCTATGTTTTGTAATTTTCATTTTAGGAGCTTGACTTATTTTTTTCTCTCTCATA
AAAACACATTTGTTTTAATTGTAGGAGAAATTTTCTCAGCATTTTGCATGTTCTTTCTAATCTTTGTTGGTCTGAATATATTGGTAGTAA
TTACTGTAATTATTCAACAAAAAGCATATCCGTTCAAAAATTTTTCCACTATGTCTTTTTTCTAGTGGCTACTGTTTTAGTTTTCTAGTT
GAATATCTCTGACAAGCTTTCGTATGGTTTTGTTATATTTTCATCTACATGTAATGTGTTATTAATTTTATTAAATGAAAACTAATCACC
TTCATGTGGAAATGCTCTGAGAATTGTCCTTAGGCATTTGGTAGTAACCAGCTAACCAAGAAGAAACAGAGAAACCAGAACTTCATATGG
CAGTCCATTTAGATGAAGAATGATGATATAAAATCTGGTTCCTTCTTAGCAAAATAAAAAACAAACAAGAAAAGATACTAAATGATGTTA
ATTTTCTTACTTTATGATTTAGAAGTCCAGTTATAATATTAAAACTCTGTGACATAGTTTCTTTTACCAAAACCATGAACCTACTCCCCG
TATCAGGTATTTTCGATGGTTTAGAAGTACTCAAGTCACATCACATTCAAGTTAGAAGTTTTTTTTTTGTTGTTGTTATTTTAAATTTTT
AACAAATATAAACACCAGCAGATACTATTACTTGCTTAAAAAATTGGGAGGGGGCACTTTTCATAGTCTTGGAATGCTAAGAAGTTTTAT
TTTTAATATTGTGACAGAAAGCTTTAAGTATTTAAGAGCTCTGTATTATATTTGATACTCTTACAGTTAAAAACTTTTCAAAATTAATAC
ATTGTTAATTATTGACCAGTTTTGAAGTTTGGGTTTAACTGTAGTTGAAATGGAAGGACTCTTGTTTTACACTTGTATTAAAGATAAATT
TATTAAAATAAGTTATTTAGCACCAATGGAGTATTACATTATTTTTATGTTTTATATTTTTCTTGAGGTAGAGTTTCAGAACTCATCTAG
TATTTTGACTAATATAGTATATATTCAGTGATTACTGTTCAAATGGGACATTGGTAGAAACTTTATTAATCTATGCAAGTATCCTATAAC
CCTCAATTCAAGGCTCTTTTGTAAAAAATGTACTGGAGAACATGGCTTAGGCCTGAAACCCATCCTGAATCTATTCAGGTCACCTGTAGA
GTCTTGACTTGGATTTGCAAAGCAGATTGTTAGACTCCTTACCCAATGTGAAGTGTGAATAAGGCCTATAGGCCTGCCTCACACAGCTAA
TCAGAGGTGGCACTGAGAAAGTCAAGTCCTAATAGGTCTCCTTAAAAAAAAAAAGGAGACAAAAAGCTGGCAAGAACATGAGCCAGCTTC
CCTCAGTGCTGTCACTCTCAAGTAAAACATGGCCAAATGAATATCAAACTGGTTTATCAGATTAGTCACTCTTCCTTACTGAGGGAGTAT
CAAGTAAGGGCTGGAGAGAGACCAGATATGTGGAGTTGTTGGCTTTCAGTGGAAATGGTAGCCTCCCTGTGGGTAGAGACCAAAAGGTAG
AGAGATGACAGAAGGGAGACTCTGATTAGTGTATTTTTTTTTTGTCTATTCCTTAAAGCCCAGACACCTTTCCATTAAAATCTACTTCAA
ATCACAAGTTGATTACAATTGAGTGGAACATCCCATGTTGTAAATGGAATAATGTGTTCAGAATGCTCTTTCTTTCCCCCAATAAAGCCC
TTTATAGTGTTT

>91068_91068_11_TJP2-TMEM38B_TJP2_chr9_71845148_ENST00000539225_TMEM38B_chr9_108536146_ENST00000374688_length(amino acids)=659AA_BP=588
MKTAQALHRMWIQAVKKLRRWKGRVSPSASSPLVFPNLSSWEGEGSKTILTAPGMEELIWEQYTVTLQKDSKRGFGIAVSGGRDNPHFEN
GETSIVISDVLPGGPADGLLQENDRVVMVNGTPMEDVLHSFAVQQLRKSGKVAAIVVKRPRKVQVAALQASPPLDQDDRAFEVMDEFDGR
SFRSGYSERSRLNSHGGRSRSWEDSPERGRPHERARSRERDLSRDRSRGRSLERGLDQDHARTRDRSRGRSLERGLDHDFGPSRDRDRDR
SRGRSIDQDYERAYHRAYDPDYERAYSPEYRRGARHDARSRGPRSRSREHPHSRSPSPEPRGRPGPIGVLLMKSRANEEYGLRLGSQIFV
KEMTRTGLATKDGNLHEGDIILKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSQQTLINIPSLNDSDSEIEDISEIESNRSFSPEER
RHQYSDYDYHSSSEKLKERPSSREDTPSRLSRMGATPTPFKSTGDIAGTVVPETNKEPRYQEDPPAPQPKAAPRTFLRPSPEDEAIYGPN
TKMVRFKKGDSVGLRLAGGNDVGIFVAGIQEGTSAEQEGLQEGDQILKITMMTTQTSTMTFAPFEDTLSWMLFGWQQPFSSCEKKSEAKS
PSNGVGSLASKPVDVASDNVKKKHTKKNE

--------------------------------------------------------------
>91068_91068_12_TJP2-TMEM38B_TJP2_chr9_71845148_ENST00000539225_TMEM38B_chr9_108536146_ENST00000374692_length(transcript)=4512nt_BP=1764nt
ATGAAGACTGCTCAAGCCCTACATAGGATGTGGATCCAGGCTGTTAAAAAGTTGAGGAGATGGAAAGGCCGTGTGAGTCCCTCTGCAAGC
TCTCCCCTTGTTTTCCCCAACCTTTCTTCATGGGAAGGGGAGGGAAGCAAAACCATTCTCACAGCCCCAGGCATGGAAGAGCTGATATGG
GAACAGTACACTGTGACCCTACAAAAGGATTCCAAAAGAGGATTTGGAATTGCAGTGTCCGGAGGCAGAGACAACCCCCACTTTGAAAAT
GGAGAAACGTCAATTGTCATTTCTGATGTGCTCCCGGGTGGGCCTGCTGATGGGCTGCTCCAAGAAAATGACAGAGTGGTCATGGTCAAT
GGCACCCCCATGGAGGATGTGCTTCATTCGTTTGCAGTTCAGCAGCTCAGAAAAAGTGGGAAGGTCGCTGCTATTGTGGTCAAGAGGCCC
CGGAAGGTCCAGGTGGCCGCACTTCAGGCCAGCCCTCCCCTGGATCAGGATGACCGGGCTTTTGAGGTGATGGACGAGTTTGATGGCAGA
AGTTTCCGGAGTGGCTACAGCGAGAGGAGCCGGCTGAACAGCCATGGGGGGCGCAGCCGCAGCTGGGAGGACAGCCCGGAAAGGGGGCGT
CCCCATGAGCGGGCCCGGAGCCGGGAGCGGGACCTCAGCCGGGACCGGAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCAAGACCAT
GCGCGCACCCGAGACCGCAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCACGACTTTGGGCCATCCCGGGACCGGGACCGTGACCGC
AGCCGCGGCCGGAGCATTGACCAGGACTACGAGCGAGCCTATCACCGGGCCTACGACCCAGACTACGAGCGGGCCTACAGCCCGGAGTAC
AGGCGCGGGGCCCGCCACGATGCCCGCTCTCGGGGACCCCGAAGCCGCAGCCGCGAGCACCCGCACTCACGGAGCCCCAGCCCCGAGCCT
AGGGGGCGGCCGGGGCCCATCGGGGTCCTCCTGATGAAAAGCAGAGCGAACGAAGAGTATGGTCTCCGGCTTGGGAGTCAGATCTTCGTA
AAGGAAATGACCCGAACGGGTCTGGCAACTAAAGATGGCAACCTTCACGAAGGAGACATAATTCTCAAGATCAATGGGACTGTAACTGAG
AACATGTCTTTAACGGATGCTCGAAAATTGATAGAAAAGTCAAGAGGAAAACTACAGCTAGTGGTGTTGAGAGACAGCCAGCAGACCCTC
ATCAACATCCCGTCATTAAATGACAGTGACTCAGAAATAGAAGATATTTCAGAAATAGAGTCAAACCGATCATTTTCTCCAGAGGAGAGA
CGTCATCAGTATTCTGATTATGATTATCATTCCTCAAGTGAGAAGCTGAAGGAAAGGCCAAGTTCCAGAGAGGACACGCCGAGCAGATTG
TCCAGGATGGGTGCGACACCCACTCCCTTTAAGTCCACAGGGGATATTGCAGGCACAGTTGTCCCAGAGACCAACAAGGAACCCAGATAC
CAAGAGGACCCCCCAGCTCCTCAACCAAAAGCAGCCCCGAGAACTTTTCTTCGTCCTAGTCCTGAAGATGAAGCAATATATGGCCCTAAT
ACCAAAATGGTAAGGTTCAAGAAGGGAGACAGCGTGGGCCTCCGGTTGGCTGGTGGCAATGATGTCGGGATATTTGTTGCTGGCATTCAA
GAAGGGACCTCGGCGGAGCAGGAGGGCCTTCAAGAAGGAGACCAGATTCTGAAGATAACCATGATGACTACACAGACTTCTACTATGACA
TTTGCTCCTTTTGAGGATACATTGAGTTGGATGCTATTTGGCTGGCAGCAGCCGTTTTCATCATGTGAGAAGAAAAGTGAAGCAAAGTCA
CCTTCCAATGGCGTTGGGTCATTGGCCTCAAAGCCGGTAGATGTTGCCTCAGATAATGTTAAAAAGAAACATACTAAGAAGAATGAATAA
ATTTACGTGATGAGCTCTACAAGGCCAAAAATTTTTTTTCTTATCTACCTGTTATATTGTGCTAATTTTTCTATGTATGTGATGTGAAAT
GAAGACTATATATATGGAATGGAGGTGACAGAAAGAAAGAAATTCTTTGTTTGAGGGAGACTTCCCCTTTCTGGATTGTATTTGTAGAGT
GTTACGAGTGTATCATGTGATTATGCTTTACCGGTATAAGAGATTCTGTTGTGATTATTTGAATAGTTTTATATTAATAAAAGAAGACAA
AATTTTTTAAATGTTAGAAAAAGCAGATCTGTCATTGCAAAGTAACAAAAATTTTAAGCTTTTAAAAATGTAGATTTTTCATATTTTTAA
AATTTGAATCTATTTGAGCTTTAGTTCAGCAGAATTAAATTTTTACTTGACATTATCATTAAAATTGCTAGGTATGGAGAACAATTCCTA
TTTTATTTTGAACACTGAGAAGAGTAAACTTTTCCTAAAACACTTTATATTATAAATGAAAATAAATTGCTAGTTTATATTTTAGATATA
AACATCATATTTTTTATTAATACCTACATCAAATGGAAAATATCTGAAATTTTTTTTCCATAGCAGGTATTTTCTACTAGAAGTAGTTTT
ACTACTTTTCATTTAGAACAGAGTATGAGTCTTAATCTGAAGTCTTTTTCATGCCCTTGTTTTAAAAAAACTACTTTTTTTGGCCTCAAA
AAAATCAAGGGTGTAATTTTTAATAAATTGTTAATCCTATGTTTTGTAATTTTCATTTTAGGAGCTTGACTTATTTTTTTCTCTCTCATA
AAAACACATTTGTTTTAATTGTAGGAGAAATTTTCTCAGCATTTTGCATGTTCTTTCTAATCTTTGTTGGTCTGAATATATTGGTAGTAA
TTACTGTAATTATTCAACAAAAAGCATATCCGTTCAAAAATTTTTCCACTATGTCTTTTTTCTAGTGGCTACTGTTTTAGTTTTCTAGTT
GAATATCTCTGACAAGCTTTCGTATGGTTTTGTTATATTTTCATCTACATGTAATGTGTTATTAATTTTATTAAATGAAAACTAATCACC
TTCATGTGGAAATGCTCTGAGAATTGTCCTTAGGCATTTGGTAGTAACCAGCTAACCAAGAAGAAACAGAGAAACCAGAACTTCATATGG
CAGTCCATTTAGATGAAGAATGATGATATAAAATCTGGTTCCTTCTTAGCAAAATAAAAAACAAACAAGAAAAGATACTAAATGATGTTA
ATTTTCTTACTTTATGATTTAGAAGTCCAGTTATAATATTAAAACTCTGTGACATAGTTTCTTTTACCAAAACCATGAACCTACTCCCCG
TATCAGGTATTTTCGATGGTTTAGAAGTACTCAAGTCACATCACATTCAAGTTAGAAGTTTTTTTTTTGTTGTTGTTATTTTAAATTTTT
AACAAATATAAACACCAGCAGATACTATTACTTGCTTAAAAAATTGGGAGGGGGCACTTTTCATAGTCTTGGAATGCTAAGAAGTTTTAT
TTTTAATATTGTGACAGAAAGCTTTAAGTATTTAAGAGCTCTGTATTATATTTGATACTCTTACAGTTAAAAACTTTTCAAAATTAATAC
ATTGTTAATTATTGACCAGTTTTGAAGTTTGGGTTTAACTGTAGTTGAAATGGAAGGACTCTTGTTTTACACTTGTATTAAAGATAAATT
TATTAAAATAAGTTATTTAGCACCAATGGAGTATTACATTATTTTTATGTTTTATATTTTTCTTGAGGTAGAGTTTCAGAACTCATCTAG
TATTTTGACTAATATAGTATATATTCAGTGATTACTGTTCAAATGGGACATTGGTAGAAACTTTATTAATCTATGCAAGTATCCTATAAC
CCTCAATTCAAGGCTCTTTTGTAAAAAATGTACTGGAGAACATGGCTTAGGCCTGAAACCCATCCTGAATCTATTCAGGTCACCTGTAGA
GTCTTGACTTGGATTTGCAAAGCAGATTGTTAGACTCCTTACCCAATGTGAAGTGTGAATAAGGCCTATAGGCCTGCCTCACACAGCTAA
TCAGAGGTGGCACTGAGAAAGTCAAGTCCTAATAGGTCTCCTTAAAAAAAAAAAGGAGACAAAAAGCTGGCAAGAACATGAGCCAGCTTC
CCTCAGTGCTGTCACTCTCAAGTAAAACATGGCCAAATGAATATCAAACTGGTTTATCAGATTAGTCACTCTTCCTTACTGAGGGAGTAT
CAAGTAAGGGCTGGAGAGAGACCAGATATGTGGAGTTGTTGGCTTTCAGTGGAAATGGTAGCCTCCCTGTGGGTAGAGACCAAAAGGTAG
AGAGATGACAGAAGGGAGACTCTGATTAGTGTATTTTTTTTTTGTCTATTCCTTAAAGCCCAGACACCTTTCCATTAAAATCTACTTCAA
ATCACAAGTTGATTACAATTGAGTGGAACATCCCATGTTGTAAATGGAATAATGTGTTCAGAATGCTCTTTCTTTCCCCCAATAAAGCCC
TTTATAGTGTTT

>91068_91068_12_TJP2-TMEM38B_TJP2_chr9_71845148_ENST00000539225_TMEM38B_chr9_108536146_ENST00000374692_length(amino acids)=659AA_BP=588
MKTAQALHRMWIQAVKKLRRWKGRVSPSASSPLVFPNLSSWEGEGSKTILTAPGMEELIWEQYTVTLQKDSKRGFGIAVSGGRDNPHFEN
GETSIVISDVLPGGPADGLLQENDRVVMVNGTPMEDVLHSFAVQQLRKSGKVAAIVVKRPRKVQVAALQASPPLDQDDRAFEVMDEFDGR
SFRSGYSERSRLNSHGGRSRSWEDSPERGRPHERARSRERDLSRDRSRGRSLERGLDQDHARTRDRSRGRSLERGLDHDFGPSRDRDRDR
SRGRSIDQDYERAYHRAYDPDYERAYSPEYRRGARHDARSRGPRSRSREHPHSRSPSPEPRGRPGPIGVLLMKSRANEEYGLRLGSQIFV
KEMTRTGLATKDGNLHEGDIILKINGTVTENMSLTDARKLIEKSRGKLQLVVLRDSQQTLINIPSLNDSDSEIEDISEIESNRSFSPEER
RHQYSDYDYHSSSEKLKERPSSREDTPSRLSRMGATPTPFKSTGDIAGTVVPETNKEPRYQEDPPAPQPKAAPRTFLRPSPEDEAIYGPN
TKMVRFKKGDSVGLRLAGGNDVGIFVAGIQEGTSAEQEGLQEGDQILKITMMTTQTSTMTFAPFEDTLSWMLFGWQQPFSSCEKKSEAKS
PSNGVGSLASKPVDVASDNVKKKHTKKNE

--------------------------------------------------------------

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Fusion Gene PPI Analysis for TJP2-TMEM38B


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneTJP2chr9:71845148chr9:108536146ENST00000265384+11191188_1190557.0994.0SCRIB
HgeneTJP2chr9:71845148chr9:108536146ENST00000348208+11211188_1190557.01044.0SCRIB
HgeneTJP2chr9:71845148chr9:108536146ENST00000377245+11231188_1190557.01191.0SCRIB
HgeneTJP2chr9:71845148chr9:108536146ENST00000453658+12221188_1190534.01021.0SCRIB
HgeneTJP2chr9:71845148chr9:108536146ENST00000535702+11221188_1190561.01158.0SCRIB
HgeneTJP2chr9:71845148chr9:108536146ENST00000539225+11231188_1190588.01222.0SCRIB


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for TJP2-TMEM38B


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TJP2-TMEM38B


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneTJP2C3711374Nonsyndromic Deafness6CLINGEN
HgeneTJP2C1384666hearing impairment2CTD_human;GENOMICS_ENGLAND
HgeneTJP2C1843139Hypercholanemia, Familial2CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
HgeneTJP2C2931067Cholestasis, progressive familial intrahepatic 42CTD_human;GENOMICS_ENGLAND;ORPHANET
HgeneTJP2C0008372Intrahepatic Cholestasis1CTD_human
TgeneC0268363Osteogenesis imperfecta type IV (disorder)2ORPHANET
TgeneC0019193Hepatitis, Toxic1CTD_human
TgeneC0029434Osteogenesis Imperfecta1GENOMICS_ENGLAND
TgeneC0860207Drug-Induced Liver Disease1CTD_human
TgeneC1262760Hepatitis, Drug-Induced1CTD_human
TgeneC3554428OSTEOGENESIS IMPERFECTA, TYPE XIV1CTD_human;GENOMICS_ENGLAND
TgeneC3658290Drug-Induced Acute Liver Injury1CTD_human
TgeneC4277682Chemical and Drug Induced Liver Injury1CTD_human
TgeneC4279912Chemically-Induced Liver Toxicity1CTD_human