Fusion Gene Studies
in Kim Lab

FusionBase FusionGDB FusionGDB2 FusionPDB FusionNeoAntigen FusionAI FusionNW FGviewer Publication Contact
FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:ACY1-BAP1 (FusionGDB2 ID:HG95TG8314)

Fusion Gene Summary for ACY1-BAP1

check button Fusion gene summary
Fusion gene informationFusion gene name: ACY1-BAP1
Fusion gene ID: hg95tg8314
HgeneTgene
Gene symbol

ACY1

BAP1

Gene ID

95

8314

Gene nameaminoacylase 1BRCA1 associated protein 1
SynonymsACY-1|ACY1D|HEL-S-5HUCEP-13|UCHL2|hucep-6
Cytomap('ACY1')('BAP1')

3p21.2

3p21.1

Type of geneprotein-codingprotein-coding
Descriptionaminoacylase-1N-acyl-L-amino-acid amidohydrolaseacylaseepididymis secretory protein Li 5ubiquitin carboxyl-terminal hydrolase BAP1BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)cerebral protein 6cerebral protein-13
Modification date2020031320200315
UniProtAcc

Q03154

.
Ensembl transtripts involved in fusion geneENST00000404366, ENST00000458031, 
ENST00000476351, ENST00000476854, 
ENST00000494103, ENST00000468068, 
Fusion gene scores* DoF score1 X 1 X 1=15 X 5 X 2=50
# samples 15
** MAII scorelog2(1/1*10)=3.32192809488736log2(5/50*10)=0
Context

PubMed: ACY1 [Title/Abstract] AND BAP1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointACY1(52021640)-BAP1(52441476), # samples:2
Anticipated loss of major functional domain due to fusion event.ACY1-BAP1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ACY1-BAP1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneBAP1

GO:0016579

protein deubiquitination

18757409|19815555

TgeneBAP1

GO:0035520

monoubiquitinated protein deubiquitination

24703950

TgeneBAP1

GO:0035522

monoubiquitinated histone H2A deubiquitination

20436459|25451922

TgeneBAP1

GO:0045892

negative regulation of transcription, DNA-templated

25451922


check buttonFusion gene breakpoints across ACY1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across BAP1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4MESOTCGA-LK-A4O5-01AACY1chr3

52021640

+BAP1chr3

52441476

-


Top

Fusion Gene ORF analysis for ACY1-BAP1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000404366ENST00000296288ACY1chr3

52021640

+BAP1chr3

52441476

-
In-frameENST00000404366ENST00000460680ACY1chr3

52021640

+BAP1chr3

52441476

-
In-frameENST00000458031ENST00000296288ACY1chr3

52021640

+BAP1chr3

52441476

-
In-frameENST00000458031ENST00000460680ACY1chr3

52021640

+BAP1chr3

52441476

-
In-frameENST00000476351ENST00000296288ACY1chr3

52021640

+BAP1chr3

52441476

-
In-frameENST00000476351ENST00000460680ACY1chr3

52021640

+BAP1chr3

52441476

-
In-frameENST00000476854ENST00000296288ACY1chr3

52021640

+BAP1chr3

52441476

-
In-frameENST00000476854ENST00000460680ACY1chr3

52021640

+BAP1chr3

52441476

-
In-frameENST00000494103ENST00000296288ACY1chr3

52021640

+BAP1chr3

52441476

-
In-frameENST00000494103ENST00000460680ACY1chr3

52021640

+BAP1chr3

52441476

-
intron-3CDSENST00000468068ENST00000296288ACY1chr3

52021640

+BAP1chr3

52441476

-
intron-3CDSENST00000468068ENST00000460680ACY1chr3

52021640

+BAP1chr3

52441476

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000458031ACY1chr352021640+ENST00000460680BAP1chr352441476-4512142223132361001
ENST00000458031ACY1chr352021640+ENST00000296288BAP1chr352441476-444514222313182983
ENST00000494103ACY1chr352021640+ENST00000460680BAP1chr352441476-39608701652684839
ENST00000494103ACY1chr352021640+ENST00000296288BAP1chr352441476-38938701652630821
ENST00000476854ACY1chr352021640+ENST00000460680BAP1chr352441476-39818911652705846
ENST00000476854ACY1chr352021640+ENST00000296288BAP1chr352441476-39148911652651828
ENST00000476351ACY1chr352021640+ENST00000460680BAP1chr352441476-40719811652795876
ENST00000476351ACY1chr352021640+ENST00000296288BAP1chr352441476-40049811652741858
ENST00000404366ACY1chr352021640+ENST00000460680BAP1chr352441476-415710671462881911
ENST00000404366ACY1chr352021640+ENST00000296288BAP1chr352441476-409010671462827893

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000458031ENST00000460680ACY1chr352021640+BAP1chr352441476-0.0043956260.9956044
ENST00000458031ENST00000296288ACY1chr352021640+BAP1chr352441476-0.0040372570.9959628
ENST00000494103ENST00000460680ACY1chr352021640+BAP1chr352441476-0.0126771260.98732287
ENST00000494103ENST00000296288ACY1chr352021640+BAP1chr352441476-0.0130932810.98690665
ENST00000476854ENST00000460680ACY1chr352021640+BAP1chr352441476-0.0134751770.9865248
ENST00000476854ENST00000296288ACY1chr352021640+BAP1chr352441476-0.0144177020.9855823
ENST00000476351ENST00000460680ACY1chr352021640+BAP1chr352441476-0.0085146510.9914854
ENST00000476351ENST00000296288ACY1chr352021640+BAP1chr352441476-0.0082843290.9917157
ENST00000404366ENST00000460680ACY1chr352021640+BAP1chr352441476-0.0065380750.99346197
ENST00000404366ENST00000296288ACY1chr352021640+BAP1chr352441476-0.0077685080.9922315

Top

Fusion Genomic Features for ACY1-BAP1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

Top

Fusion Protein Features for ACY1-BAP1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:52021640/chr3:52441476)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ACY1

Q03154

.
FUNCTION: Involved in the hydrolysis of N-acylated or N-acetylated amino acids (except L-aspartate). {ECO:0000269|PubMed:12933810}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneBAP1chr3:52021640chr3:52441476ENST00000460680417630_661125730.0Coiled coilOntology_term=ECO:0000255

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


Top

Fusion Gene Sequence for ACY1-BAP1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>1916_1916_1_ACY1-BAP1_ACY1_chr3_52021640_ENST00000404366_BAP1_chr3_52441476_ENST00000296288_length(transcript)=4090nt_BP=1067nt
CGTGGTGGGCGGACCGGGGCGGTCCTGAGCCTGCGACCTCGCAGGCGACCTCGCTGGACCCTAAGTCCAGGCCACAGTCAGGGAAGGGCG
CTGAGAGGCGAGCGTGAGCCCAGCGACAGGAGAGTGAGCTCACCACGCGCAGCGCCATGACCAGCAAGGGTCCCGAGGAGGAGCACCCAT
CGGTGACGCTCTTCCGCCAGTACCTGCGTATCCGCACTGTCCAGCCCAAGCCTGACTATGGAGCTGCTGTGGCTTTCTTTGAGGAGACAG
CCCGCCAGCTGGGCCTGGGCTGTCAGAAAGTAGAGGTGGCACCTGGCTATGTGGTGACCGTGTTGACCTGGCCAGGCACCAACCCTACAC
TCTCCTCCATCTTGCTCAACTCCCACACGGATGTGGTGCCTGTCTTCAAGGAACATTGGAGTCACGACCCCTTTGAGGCCTTCAAGGATT
CTGAGGGCTACATCTATGCCAGGGGTGCCCAGGACATGAAGTGCGTCAGCATCCAGTACCTGGAAGCTGTGAGGAGGCTGAAGGTGGAGG
GCCACCGGTTCCCCAGAACCATCCACATGACCTTTGTGCCTGATGAGGAGGTTGGGGGTCACCAAGGCATGGAGCTGTTCGTGCAGCGGC
CTGAGTTCCACGCCCTGAGGGCAGGCTTTGCCCTGGATGAGGGCATAGCCAATCCCACTGATGCCTTCACTGTCTTTTATAGTGAGCGGA
GTCCCTGGTGGGTGCGGGTTACCAGCACTGGGAGGCCAGGCCATGCCTCACGCTTCATGGAGGACACAGCAGCAGAGAAGCTGCACAAGG
TTGTAAACTCCATCCTGGCATTCCGGGAGAAGGAATGGCAGAGGCTGCAGTCAAACCCCCACCTGAAAGAGGGGTCCGTGACCTCCGTGA
ACCTGACTAAGCTAGAGGGTGGCGTGGCCTATAACGTGATACCTGCCACCATGAGCGCCAGCTTTGACTTCCGTGTGGCACCGGATGTGG
ACTTCAAGGCTTTTGAGGAGCAGCTGCAGAGCTGGTGCCAGGCAGCTGGCGAGGGGGTCACCCTAGAGTTTGCTCAGAGCAAAGGATATG
CGATTGGCAATGCCCCGGAGTTGGCCAAGGCCCATAATAGCCATGCCAGGCCCGAGCCACGCCACCTCCCTGAGAAGCAGAATGGCCTTA
GTGCAGTGCGGACCATGGAGGCGTTCCACTTTGTCAGCTATGTGCCTATCACAGGCCGGCTCTTTGAGCTGGATGGGCTGAAGGTCTACC
CCATTGACCATGGGCCCTGGGGGGAGGACGAGGAGTGGACAGACAAGGCCCGGCGGGTCATCATGGAGCGTATCGGCCTCGCCACTGCAG
GGATCAAGTATGAGGCCAGGCTGCATGTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGATAAGAGTAACACAGC
CAGAGCTGATTCAGACCCACAAGTCTCAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCCGCTGGTGCTGGAAG
CAAACAGGGCCCCTGCAGCCTCTGAGGGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGCCCCATCCCACAGCC
CTCCCAACAAACCCAAGCTAGTGGTGAAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCATTGTCCAGCGGCTGC
CGGCCTTTCTAGACAATCACAATTATGCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCGCAGCCGAGTTCCAG
TCCGCCCACCCCAGCAGTACTCAGATGATGAGGATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAACTCTGCCCTTAGGT
ATAAGGGGAAGGGAACAGGGAAGCCAGGGGCATTGAGCGGTTCTGCTGATGGGCAACTGTCAGTGCTGCAGCCCAACACCATCAACGTCT
TGGCTGAGAAGCTCAAAGAGTCCCAGAAGGACCTCTCAATTCCTCTGTCCATCAAGACTAGCAGCGGGGCTGGGAGTCCGGCTGTGGCAG
TGCCCACACACTCGCAGCCCTCACCCACCCCCAGCAATGAGAGTACAGACACGGCCTCTGAGATCGGCAGTGCTTTCAACTCGCCACTGC
GCTCGCCTATCCGCTCAGCCAACCCGACGCGGCCCTCCAGCCCTGTCACCTCCCACATCTCCAAGGTGCTTTTTGGAGAGGATGACAGCC
TGCTGCGTGTTGACTGCATACGCTACAACCGTGCTGTCCGTGATCTGGGTCCTGTCATCAGCACAGGCCTGCTGCACCTGGCTGAGGATG
GGGTGCTGAGTCCCCTGGCGCTGACAGAGGGTGGGAAGGGTTCCTCGCCCTCCATCAGACCAATCCAAGGCAGCCAGGGGTCCAGCAGCC
CAGTGGAGAAGGAGGTCGTGGAAGCCACGGACAGCAGAGAGAAGACGGGGATGGTGAGGCCTGGCGAGCCCTTGAGTGGGGAGAAATACT
CACCCAAGGAGCTGCTGGCACTGCTGAAGTGTGTGGAGGCTGAGATTGCAAACTATGAGGCGTGCCTCAAGGAGGAGGTAGAGAAGAGGA
AGAAGTTCAAGATTGATGACCAGAGAAGGACCCACAACTACGATGAGTTCATCTGCACCTTTATCTCCATGCTGGCTCAGGAAGGCATGC
TGGCCAACCTAGTGGAGCAGAACATCTCCGTGCGGCGGCGCCAAGGGGTCAGCATCGGCCGGCTCCACAAGCAGCGGAAGCCTGACCGGC
GGAAACGCTCTCGCCCCTACAAGGCCAAGCGCCAGTGAGGACTGCTGGCCCTGACTCTGCAGCCCACTCTTGCCGTGTGGCCCTCACCAG
GGTCCTTCCCTGCCCCACTTCCCCTTTTCCCAGTATTACTGAATAGTCCCAGCTGGAGAGTCCAGGCCCTGGGAATGGGAGGAACCAGGC
CACATTCCTTCCATCGTGCCCTGAGGCCTGACACGGCAGATCAGCCCCATAGTGCTCAGGAGGCAGCATCTGGAGTTGGGGCACAGCGAG
GTACTGCAGCTTCCTCCACAGCCGGCTGTGGAGCAGCAGGACCTGGCCCTTCTGCCTGGGCAGCAGAATATATATTTTACCTATCAGAGA
CATCTATTTTTCTGGGCTCCAACCCAACATGCCACCATGTTGACATAAGTTCCTACCTGACTATGCTTTCTCTCCTAGGAGCTGTCCTGG
TGGGCCCAGGTCCTTGTATCATGCCACGGTCCCAACTACAGGGTCCTAGCTGGGGGCCTGGGTGGGCCCTGGGCTCTGGGCCCTGCTGCT
CTAGCCCCAGCCACCAGCCTGTCCCTGTTGTAAGGAAGCCAGGTCTTCTCTCTTCATTCCTCTTAGGAGAGTGCCAAACTCAGGGACCCA
GCACTGGGCTGGGTTGGGAGTAGGGTGTCCCAGTGGGGTTGGGGTGAGCAGGCTGCTGGGATCCCATGGCCTGAGCAGAGCATGTGGGAA
CTGTTCAGTGGCCTGTGAACTGTCTTCCTTGTTCTAGCCAGGCTGTTCAAGACTGCTCTCCATAGCAAGGTTCTAGGGCTCTTCGCCTTC
AGTGTTGTGGCCCTAGCTATGGGCCTAAATTGGGCTCTAGGTCTCTGTCCCTGGCGCTTGAGGCTCAGAAGAGCCTCTGTCCAGCCCCTC
AGTATTACCATGTCTCCCTCTCAGGGGTAGCAGAGACAGGGTTGCTTATAGGAAGCTGGCACCACTCAGCTCTTCCTGCTACTCCAGTTT
CCTCAGCCTCTGCAAGGCACTCAGGGTGGGGGACAGCAGGATCAAGACAACCCGTTGGAGCCCCTGTGTTCCAGAGGACCTGATGCCAAG
GGGTAATGGGCCCAGCAGTGCCTCTGGAGCCCAGGCCCCAACACAGCCCCATGGCCTCTGCCAGATGGCTTTGAAAAAGGTGATCCAAGC
AGGCCCCTTTATCTGTACATAGTGACTGAGTGGGGGGTGCTGGCAAGTGTGGCAGCTGCCTCTGGGCTGAGCACAGCTTGACCCCTCTAG

>1916_1916_1_ACY1-BAP1_ACY1_chr3_52021640_ENST00000404366_BAP1_chr3_52441476_ENST00000296288_length(amino acids)=893AA_BP=307
MTSKGPEEEHPSVTLFRQYLRIRTVQPKPDYGAAVAFFEETARQLGLGCQKVEVAPGYVVTVLTWPGTNPTLSSILLNSHTDVVPVFKEH
WSHDPFEAFKDSEGYIYARGAQDMKCVSIQYLEAVRRLKVEGHRFPRTIHMTFVPDEEVGGHQGMELFVQRPEFHALRAGFALDEGIANP
TDAFTVFYSERSPWWVRVTSTGRPGHASRFMEDTAAEKLHKVVNSILAFREKEWQRLQSNPHLKEGSVTSVNLTKLEGGVAYNVIPATMS
ASFDFRVAPDVDFKAFEEQLQSWCQAAGEGVTLEFAQSKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITG
RLFELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGIKYEARLHVLKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESK
SASNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAFLDNHNYAKSPMQEEED
LAAGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRYKGKGTGKPGALSGSADGQLSVLQPNTINVLAEKLKESQKDLSIPLSIK
TSSGAGSPAVAVPTHSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSLLRVDCIRYNRAVRDLGPV
ISTGLLHLAEDGVLSPLALTEGGKGSSPSIRPIQGSQGSSSPVEKEVVEATDSREKTGMVRPGEPLSGEKYSPKELLALLKCVEAEIANY

--------------------------------------------------------------
>1916_1916_2_ACY1-BAP1_ACY1_chr3_52021640_ENST00000404366_BAP1_chr3_52441476_ENST00000460680_length(transcript)=4157nt_BP=1067nt
CGTGGTGGGCGGACCGGGGCGGTCCTGAGCCTGCGACCTCGCAGGCGACCTCGCTGGACCCTAAGTCCAGGCCACAGTCAGGGAAGGGCG
CTGAGAGGCGAGCGTGAGCCCAGCGACAGGAGAGTGAGCTCACCACGCGCAGCGCCATGACCAGCAAGGGTCCCGAGGAGGAGCACCCAT
CGGTGACGCTCTTCCGCCAGTACCTGCGTATCCGCACTGTCCAGCCCAAGCCTGACTATGGAGCTGCTGTGGCTTTCTTTGAGGAGACAG
CCCGCCAGCTGGGCCTGGGCTGTCAGAAAGTAGAGGTGGCACCTGGCTATGTGGTGACCGTGTTGACCTGGCCAGGCACCAACCCTACAC
TCTCCTCCATCTTGCTCAACTCCCACACGGATGTGGTGCCTGTCTTCAAGGAACATTGGAGTCACGACCCCTTTGAGGCCTTCAAGGATT
CTGAGGGCTACATCTATGCCAGGGGTGCCCAGGACATGAAGTGCGTCAGCATCCAGTACCTGGAAGCTGTGAGGAGGCTGAAGGTGGAGG
GCCACCGGTTCCCCAGAACCATCCACATGACCTTTGTGCCTGATGAGGAGGTTGGGGGTCACCAAGGCATGGAGCTGTTCGTGCAGCGGC
CTGAGTTCCACGCCCTGAGGGCAGGCTTTGCCCTGGATGAGGGCATAGCCAATCCCACTGATGCCTTCACTGTCTTTTATAGTGAGCGGA
GTCCCTGGTGGGTGCGGGTTACCAGCACTGGGAGGCCAGGCCATGCCTCACGCTTCATGGAGGACACAGCAGCAGAGAAGCTGCACAAGG
TTGTAAACTCCATCCTGGCATTCCGGGAGAAGGAATGGCAGAGGCTGCAGTCAAACCCCCACCTGAAAGAGGGGTCCGTGACCTCCGTGA
ACCTGACTAAGCTAGAGGGTGGCGTGGCCTATAACGTGATACCTGCCACCATGAGCGCCAGCTTTGACTTCCGTGTGGCACCGGATGTGG
ACTTCAAGGCTTTTGAGGAGCAGCTGCAGAGCTGGTGCCAGGCAGCTGGCGAGGGGGTCACCCTAGAGTTTGCTCAGAGCAAAGGATATG
CGATTGGCAATGCCCCGGAGTTGGCCAAGGCCCATAATAGCCATGCCAGGCCCGAGCCACGCCACCTCCCTGAGAAGCAGAATGGCCTTA
GTGCAGTGCGGACCATGGAGGCGTTCCACTTTGTCAGCTATGTGCCTATCACAGGCCGGCTCTTTGAGCTGGATGGGCTGAAGGTCTACC
CCATTGACCATGGGCCCTGGGGGGAGGACGAGGAGTGGACAGACAAGGCCCGGCGGGTCATCATGGAGCGTATCGGCCTCGCCACTGCAG
GGGAGCCCTACCACGACATCCGCTTCAACCTGATGGCAGTGGTGCCCGACCGCAGGATCAAGTATGAGGCCAGGCTGCATGTGCTGAAGG
TGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGATAAGAGTAACACAGCCAGAGCTGATTCAGACCCACAAGTCTCAAGAGTCAC
AGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCCGCTGGTGCTGGAAGCAAACAGGGCCCCTGCAGCCTCTGAGGGCAACCACA
CAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGCCCCATCCCACAGCCCTCCCAACAAACCCAAGCTAGTGGTGAAGCCTCCAG
GCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCATTGTCCAGCGGCTGCCGGCCTTTCTAGACAATCACAATTATGCCAAGTCCC
CCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCGCAGCCGAGTTCCAGTCCGCCCACCCCAGCAGTACTCAGATGATGAGGATG
ACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAACTCTGCCCTTAGGTATAAGGGGAAGGGAACAGGGAAGCCAGGGGCATTGA
GCGGTTCTGCTGATGGGCAACTGTCAGTGCTGCAGCCCAACACCATCAACGTCTTGGCTGAGAAGCTCAAAGAGTCCCAGAAGGACCTCT
CAATTCCTCTGTCCATCAAGACTAGCAGCGGGGCTGGGAGTCCGGCTGTGGCAGTGCCCACACACTCGCAGCCCTCACCCACCCCCAGCA
ATGAGAGTACAGACACGGCCTCTGAGATCGGCAGTGCTTTCAACTCGCCACTGCGCTCGCCTATCCGCTCAGCCAACCCGACGCGGCCCT
CCAGCCCTGTCACCTCCCACATCTCCAAGGTGCTTTTTGGAGAGGATGACAGCCTGCTGCGTGTTGACTGCATACGCTACAACCGTGCTG
TCCGTGATCTGGGTCCTGTCATCAGCACAGGCCTGCTGCACCTGGCTGAGGATGGGGTGCTGAGTCCCCTGGCGCTGACAGAGGGTGGGA
AGGGTTCCTCGCCCTCCATCAGACCAATCCAAGGCAGCCAGGGGTCCAGCAGCCCAGTGGAGAAGGAGGTCGTGGAAGCCACGGACAGCA
GAGAGAAGACGGGGATGGTGAGGCCTGGCGAGCCCTTGAGTGGGGAGAAATACTCACCCAAGGAGCTGCTGGCACTGCTGAAGTGTGTGG
AGGCTGAGATTGCAAACTATGAGGCGTGCCTCAAGGAGGAGGTAGAGAAGAGGAAGAAGTTCAAGATTGATGACCAGAGAAGGACCCACA
ACTACGATGAGTTCATCTGCACCTTTATCTCCATGCTGGCTCAGGAAGGCATGCTGGCCAACCTAGTGGAGCAGAACATCTCCGTGCGGC
GGCGCCAAGGGGTCAGCATCGGCCGGCTCCACAAGCAGCGGAAGCCTGACCGGCGGAAACGCTCTCGCCCCTACAAGGCCAAGCGCCAGT
GAGGACTGCTGGCCCTGACTCTGCAGCCCACTCTTGCCGTGTGGCCCTCACCAGGGTCCTTCCCTGCCCCACTTCCCCTTTTCCCAGTAT
TACTGAATAGTCCCAGCTGGAGAGTCCAGGCCCTGGGAATGGGAGGAACCAGGCCACATTCCTTCCATCGTGCCCTGAGGCCTGACACGG
CAGATCAGCCCCATAGTGCTCAGGAGGCAGCATCTGGAGTTGGGGCACAGCGAGGTACTGCAGCTTCCTCCACAGCCGGCTGTGGAGCAG
CAGGACCTGGCCCTTCTGCCTGGGCAGCAGAATATATATTTTACCTATCAGAGACATCTATTTTTCTGGGCTCCAACCCAACATGCCACC
ATGTTGACATAAGTTCCTACCTGACTATGCTTTCTCTCCTAGGAGCTGTCCTGGTGGGCCCAGGTCCTTGTATCATGCCACGGTCCCAAC
TACAGGGTCCTAGCTGGGGGCCTGGGTGGGCCCTGGGCTCTGGGCCCTGCTGCTCTAGCCCCAGCCACCAGCCTGTCCCTGTTGTAAGGA
AGCCAGGTCTTCTCTCTTCATTCCTCTTAGGAGAGTGCCAAACTCAGGGACCCAGCACTGGGCTGGGTTGGGAGTAGGGTGTCCCAGTGG
GGTTGGGGTGAGCAGGCTGCTGGGATCCCATGGCCTGAGCAGAGCATGTGGGAACTGTTCAGTGGCCTGTGAACTGTCTTCCTTGTTCTA
GCCAGGCTGTTCAAGACTGCTCTCCATAGCAAGGTTCTAGGGCTCTTCGCCTTCAGTGTTGTGGCCCTAGCTATGGGCCTAAATTGGGCT
CTAGGTCTCTGTCCCTGGCGCTTGAGGCTCAGAAGAGCCTCTGTCCAGCCCCTCAGTATTACCATGTCTCCCTCTCAGGGGTAGCAGAGA
CAGGGTTGCTTATAGGAAGCTGGCACCACTCAGCTCTTCCTGCTACTCCAGTTTCCTCAGCCTCTGCAAGGCACTCAGGGTGGGGGACAG
CAGGATCAAGACAACCCGTTGGAGCCCCTGTGTTCCAGAGGACCTGATGCCAAGGGGTAATGGGCCCAGCAGTGCCTCTGGAGCCCAGGC
CCCAACACAGCCCCATGGCCTCTGCCAGATGGCTTTGAAAAAGGTGATCCAAGCAGGCCCCTTTATCTGTACATAGTGACTGAGTGGGGG
GTGCTGGCAAGTGTGGCAGCTGCCTCTGGGCTGAGCACAGCTTGACCCCTCTAGCCCCTGTAAATACTGGATCAATGAATGAATAAAACT

>1916_1916_2_ACY1-BAP1_ACY1_chr3_52021640_ENST00000404366_BAP1_chr3_52441476_ENST00000460680_length(amino acids)=911AA_BP=307
MTSKGPEEEHPSVTLFRQYLRIRTVQPKPDYGAAVAFFEETARQLGLGCQKVEVAPGYVVTVLTWPGTNPTLSSILLNSHTDVVPVFKEH
WSHDPFEAFKDSEGYIYARGAQDMKCVSIQYLEAVRRLKVEGHRFPRTIHMTFVPDEEVGGHQGMELFVQRPEFHALRAGFALDEGIANP
TDAFTVFYSERSPWWVRVTSTGRPGHASRFMEDTAAEKLHKVVNSILAFREKEWQRLQSNPHLKEGSVTSVNLTKLEGGVAYNVIPATMS
ASFDFRVAPDVDFKAFEEQLQSWCQAAGEGVTLEFAQSKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITG
RLFELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRIKYEARLHVLKVNRQTVLEALQQLIRVTQP
ELIQTHKSQESQLPEESKSASNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLP
AFLDNHNYAKSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRYKGKGTGKPGALSGSADGQLSVLQPNTINVL
AEKLKESQKDLSIPLSIKTSSGAGSPAVAVPTHSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSL
LRVDCIRYNRAVRDLGPVISTGLLHLAEDGVLSPLALTEGGKGSSPSIRPIQGSQGSSSPVEKEVVEATDSREKTGMVRPGEPLSGEKYS
PKELLALLKCVEAEIANYEACLKEEVEKRKKFKIDDQRRTHNYDEFICTFISMLAQEGMLANLVEQNISVRRRQGVSIGRLHKQRKPDRR

--------------------------------------------------------------
>1916_1916_3_ACY1-BAP1_ACY1_chr3_52021640_ENST00000458031_BAP1_chr3_52441476_ENST00000296288_length(transcript)=4445nt_BP=1422nt
CGGCTGCGGAGTGCGCAGGCGCGCCGAGATGGCCGCGCTCCTGGCCGCCTAGAGCCGGAGCGGCCCGCGGAGCTGCGGAGGCAGCCATGG
TCGGGGCGCTGTGCGGCTGCTGGTTCCGCCTGGGCGGGGCCCGCCCGCTCATCCCGTTGGGCCCGACTGTGGTACAGACCTCCATGAGCC
GGTCCCAGGTAGCCCTGCTGGGCCTGAGTCTGCTGCTCATGCTCCTACTGTATGTGGGGCTGCCAGGCCCCCCTGAGCAGACTTCCTGCC
TCTGGGGAGACCCCAATGTCACAGTCCTGGCTGGTCTCACCCCTGGCAACTCGCCCATCTTTTACCGCGAGGTGCTCCCACTCAACCAGG
CACACAGGGTGGAGGTGGTGCTGCTTCATGGAAAGGCCTTTAACTCTCACACGTGGGAGCAGCTGGGCACACTGCAGCTACTGTCACAGA
GGGGCTACCGGGCCGTGGCCCTTGACCTTCCAGCTCACCACGCGCAGCGCCATGACCAGCAAGGGTCCCGAGGAGGAGCACCCATCGGTG
ACGCTCTTCCGCCAGTACCTGCGTATCCGCACTGTCCAGCCCAAGCCTGACTATGGAGCTGCTGTGGCTTTCTTTGAGGAGACAGCCCGC
CAGCTGGGCCTGGGCTGTCAGAAAGTAGAGGTGGCACCTGGCTATGTGGTGACCGTGTTGACCTGGCCAGGCACCAACCCTACACTCTCC
TCCATCTTGCTCAACTCCCACACGGATGTGGTGCCTGTCTTCAAGGAACATTGGAGTCACGACCCCTTTGAGGCCTTCAAGGATTCTGAG
GGCTACATCTATGCCAGGGGTGCCCAGGACATGAAGTGCGTCAGCATCCAGTACCTGGAAGCTGTGAGGAGGCTGAAGGTGGAGGGCCAC
CGGTTCCCCAGAACCATCCACATGACCTTTGTGCCTGATGAGGAGGTTGGGGGTCACCAAGGCATGGAGCTGTTCGTGCAGCGGCCTGAG
TTCCACGCCCTGAGGGCAGGCTTTGCCCTGGATGAGGGCATAGCCAATCCCACTGATGCCTTCACTGTCTTTTATAGTGAGCGGAGTCCC
TGGTGGGTGCGGGTTACCAGCACTGGGAGGCCAGGCCATGCCTCACGCTTCATGGAGGACACAGCAGCAGAGAAGCTGCACAAGGTTGTA
AACTCCATCCTGGCATTCCGGGAGAAGGAATGGCAGAGGCTGCAGTCAAACCCCCACCTGAAAGAGGGGTCCGTGACCTCCGTGAACCTG
ACTAAGCTAGAGGGTGGCGTGGCCTATAACGTGATACCTGCCACCATGAGCGCCAGCTTTGACTTCCGTGTGGCACCGGATGTGGACTTC
AAGGCTTTTGAGGAGCAGCTGCAGAGCTGGTGCCAGGCAGCTGGCGAGGGGGTCACCCTAGAGTTTGCTCAGAGCAAAGGATATGCGATT
GGCAATGCCCCGGAGTTGGCCAAGGCCCATAATAGCCATGCCAGGCCCGAGCCACGCCACCTCCCTGAGAAGCAGAATGGCCTTAGTGCA
GTGCGGACCATGGAGGCGTTCCACTTTGTCAGCTATGTGCCTATCACAGGCCGGCTCTTTGAGCTGGATGGGCTGAAGGTCTACCCCATT
GACCATGGGCCCTGGGGGGAGGACGAGGAGTGGACAGACAAGGCCCGGCGGGTCATCATGGAGCGTATCGGCCTCGCCACTGCAGGGATC
AAGTATGAGGCCAGGCTGCATGTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGATAAGAGTAACACAGCCAGAG
CTGATTCAGACCCACAAGTCTCAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCCGCTGGTGCTGGAAGCAAAC
AGGGCCCCTGCAGCCTCTGAGGGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGCCCCATCCCACAGCCCTCCC
AACAAACCCAAGCTAGTGGTGAAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCATTGTCCAGCGGCTGCCGGCC
TTTCTAGACAATCACAATTATGCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCGCAGCCGAGTTCCAGTCCGC
CCACCCCAGCAGTACTCAGATGATGAGGATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAACTCTGCCCTTAGGTATAAG
GGGAAGGGAACAGGGAAGCCAGGGGCATTGAGCGGTTCTGCTGATGGGCAACTGTCAGTGCTGCAGCCCAACACCATCAACGTCTTGGCT
GAGAAGCTCAAAGAGTCCCAGAAGGACCTCTCAATTCCTCTGTCCATCAAGACTAGCAGCGGGGCTGGGAGTCCGGCTGTGGCAGTGCCC
ACACACTCGCAGCCCTCACCCACCCCCAGCAATGAGAGTACAGACACGGCCTCTGAGATCGGCAGTGCTTTCAACTCGCCACTGCGCTCG
CCTATCCGCTCAGCCAACCCGACGCGGCCCTCCAGCCCTGTCACCTCCCACATCTCCAAGGTGCTTTTTGGAGAGGATGACAGCCTGCTG
CGTGTTGACTGCATACGCTACAACCGTGCTGTCCGTGATCTGGGTCCTGTCATCAGCACAGGCCTGCTGCACCTGGCTGAGGATGGGGTG
CTGAGTCCCCTGGCGCTGACAGAGGGTGGGAAGGGTTCCTCGCCCTCCATCAGACCAATCCAAGGCAGCCAGGGGTCCAGCAGCCCAGTG
GAGAAGGAGGTCGTGGAAGCCACGGACAGCAGAGAGAAGACGGGGATGGTGAGGCCTGGCGAGCCCTTGAGTGGGGAGAAATACTCACCC
AAGGAGCTGCTGGCACTGCTGAAGTGTGTGGAGGCTGAGATTGCAAACTATGAGGCGTGCCTCAAGGAGGAGGTAGAGAAGAGGAAGAAG
TTCAAGATTGATGACCAGAGAAGGACCCACAACTACGATGAGTTCATCTGCACCTTTATCTCCATGCTGGCTCAGGAAGGCATGCTGGCC
AACCTAGTGGAGCAGAACATCTCCGTGCGGCGGCGCCAAGGGGTCAGCATCGGCCGGCTCCACAAGCAGCGGAAGCCTGACCGGCGGAAA
CGCTCTCGCCCCTACAAGGCCAAGCGCCAGTGAGGACTGCTGGCCCTGACTCTGCAGCCCACTCTTGCCGTGTGGCCCTCACCAGGGTCC
TTCCCTGCCCCACTTCCCCTTTTCCCAGTATTACTGAATAGTCCCAGCTGGAGAGTCCAGGCCCTGGGAATGGGAGGAACCAGGCCACAT
TCCTTCCATCGTGCCCTGAGGCCTGACACGGCAGATCAGCCCCATAGTGCTCAGGAGGCAGCATCTGGAGTTGGGGCACAGCGAGGTACT
GCAGCTTCCTCCACAGCCGGCTGTGGAGCAGCAGGACCTGGCCCTTCTGCCTGGGCAGCAGAATATATATTTTACCTATCAGAGACATCT
ATTTTTCTGGGCTCCAACCCAACATGCCACCATGTTGACATAAGTTCCTACCTGACTATGCTTTCTCTCCTAGGAGCTGTCCTGGTGGGC
CCAGGTCCTTGTATCATGCCACGGTCCCAACTACAGGGTCCTAGCTGGGGGCCTGGGTGGGCCCTGGGCTCTGGGCCCTGCTGCTCTAGC
CCCAGCCACCAGCCTGTCCCTGTTGTAAGGAAGCCAGGTCTTCTCTCTTCATTCCTCTTAGGAGAGTGCCAAACTCAGGGACCCAGCACT
GGGCTGGGTTGGGAGTAGGGTGTCCCAGTGGGGTTGGGGTGAGCAGGCTGCTGGGATCCCATGGCCTGAGCAGAGCATGTGGGAACTGTT
CAGTGGCCTGTGAACTGTCTTCCTTGTTCTAGCCAGGCTGTTCAAGACTGCTCTCCATAGCAAGGTTCTAGGGCTCTTCGCCTTCAGTGT
TGTGGCCCTAGCTATGGGCCTAAATTGGGCTCTAGGTCTCTGTCCCTGGCGCTTGAGGCTCAGAAGAGCCTCTGTCCAGCCCCTCAGTAT
TACCATGTCTCCCTCTCAGGGGTAGCAGAGACAGGGTTGCTTATAGGAAGCTGGCACCACTCAGCTCTTCCTGCTACTCCAGTTTCCTCA
GCCTCTGCAAGGCACTCAGGGTGGGGGACAGCAGGATCAAGACAACCCGTTGGAGCCCCTGTGTTCCAGAGGACCTGATGCCAAGGGGTA
ATGGGCCCAGCAGTGCCTCTGGAGCCCAGGCCCCAACACAGCCCCATGGCCTCTGCCAGATGGCTTTGAAAAAGGTGATCCAAGCAGGCC
CCTTTATCTGTACATAGTGACTGAGTGGGGGGTGCTGGCAAGTGTGGCAGCTGCCTCTGGGCTGAGCACAGCTTGACCCCTCTAGCCCCT

>1916_1916_3_ACY1-BAP1_ACY1_chr3_52021640_ENST00000458031_BAP1_chr3_52441476_ENST00000296288_length(amino acids)=983AA_BP=397
MWGCQAPLSRLPASGETPMSQSWLVSPLATRPSFTARCSHSTRHTGWRWCCFMERPLTLTRGSSWAHCSYCHRGATGPWPLTFQLTTRSA
MTSKGPEEEHPSVTLFRQYLRIRTVQPKPDYGAAVAFFEETARQLGLGCQKVEVAPGYVVTVLTWPGTNPTLSSILLNSHTDVVPVFKEH
WSHDPFEAFKDSEGYIYARGAQDMKCVSIQYLEAVRRLKVEGHRFPRTIHMTFVPDEEVGGHQGMELFVQRPEFHALRAGFALDEGIANP
TDAFTVFYSERSPWWVRVTSTGRPGHASRFMEDTAAEKLHKVVNSILAFREKEWQRLQSNPHLKEGSVTSVNLTKLEGGVAYNVIPATMS
ASFDFRVAPDVDFKAFEEQLQSWCQAAGEGVTLEFAQSKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITG
RLFELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGIKYEARLHVLKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESK
SASNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAFLDNHNYAKSPMQEEED
LAAGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRYKGKGTGKPGALSGSADGQLSVLQPNTINVLAEKLKESQKDLSIPLSIK
TSSGAGSPAVAVPTHSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSLLRVDCIRYNRAVRDLGPV
ISTGLLHLAEDGVLSPLALTEGGKGSSPSIRPIQGSQGSSSPVEKEVVEATDSREKTGMVRPGEPLSGEKYSPKELLALLKCVEAEIANY

--------------------------------------------------------------
>1916_1916_4_ACY1-BAP1_ACY1_chr3_52021640_ENST00000458031_BAP1_chr3_52441476_ENST00000460680_length(transcript)=4512nt_BP=1422nt
CGGCTGCGGAGTGCGCAGGCGCGCCGAGATGGCCGCGCTCCTGGCCGCCTAGAGCCGGAGCGGCCCGCGGAGCTGCGGAGGCAGCCATGG
TCGGGGCGCTGTGCGGCTGCTGGTTCCGCCTGGGCGGGGCCCGCCCGCTCATCCCGTTGGGCCCGACTGTGGTACAGACCTCCATGAGCC
GGTCCCAGGTAGCCCTGCTGGGCCTGAGTCTGCTGCTCATGCTCCTACTGTATGTGGGGCTGCCAGGCCCCCCTGAGCAGACTTCCTGCC
TCTGGGGAGACCCCAATGTCACAGTCCTGGCTGGTCTCACCCCTGGCAACTCGCCCATCTTTTACCGCGAGGTGCTCCCACTCAACCAGG
CACACAGGGTGGAGGTGGTGCTGCTTCATGGAAAGGCCTTTAACTCTCACACGTGGGAGCAGCTGGGCACACTGCAGCTACTGTCACAGA
GGGGCTACCGGGCCGTGGCCCTTGACCTTCCAGCTCACCACGCGCAGCGCCATGACCAGCAAGGGTCCCGAGGAGGAGCACCCATCGGTG
ACGCTCTTCCGCCAGTACCTGCGTATCCGCACTGTCCAGCCCAAGCCTGACTATGGAGCTGCTGTGGCTTTCTTTGAGGAGACAGCCCGC
CAGCTGGGCCTGGGCTGTCAGAAAGTAGAGGTGGCACCTGGCTATGTGGTGACCGTGTTGACCTGGCCAGGCACCAACCCTACACTCTCC
TCCATCTTGCTCAACTCCCACACGGATGTGGTGCCTGTCTTCAAGGAACATTGGAGTCACGACCCCTTTGAGGCCTTCAAGGATTCTGAG
GGCTACATCTATGCCAGGGGTGCCCAGGACATGAAGTGCGTCAGCATCCAGTACCTGGAAGCTGTGAGGAGGCTGAAGGTGGAGGGCCAC
CGGTTCCCCAGAACCATCCACATGACCTTTGTGCCTGATGAGGAGGTTGGGGGTCACCAAGGCATGGAGCTGTTCGTGCAGCGGCCTGAG
TTCCACGCCCTGAGGGCAGGCTTTGCCCTGGATGAGGGCATAGCCAATCCCACTGATGCCTTCACTGTCTTTTATAGTGAGCGGAGTCCC
TGGTGGGTGCGGGTTACCAGCACTGGGAGGCCAGGCCATGCCTCACGCTTCATGGAGGACACAGCAGCAGAGAAGCTGCACAAGGTTGTA
AACTCCATCCTGGCATTCCGGGAGAAGGAATGGCAGAGGCTGCAGTCAAACCCCCACCTGAAAGAGGGGTCCGTGACCTCCGTGAACCTG
ACTAAGCTAGAGGGTGGCGTGGCCTATAACGTGATACCTGCCACCATGAGCGCCAGCTTTGACTTCCGTGTGGCACCGGATGTGGACTTC
AAGGCTTTTGAGGAGCAGCTGCAGAGCTGGTGCCAGGCAGCTGGCGAGGGGGTCACCCTAGAGTTTGCTCAGAGCAAAGGATATGCGATT
GGCAATGCCCCGGAGTTGGCCAAGGCCCATAATAGCCATGCCAGGCCCGAGCCACGCCACCTCCCTGAGAAGCAGAATGGCCTTAGTGCA
GTGCGGACCATGGAGGCGTTCCACTTTGTCAGCTATGTGCCTATCACAGGCCGGCTCTTTGAGCTGGATGGGCTGAAGGTCTACCCCATT
GACCATGGGCCCTGGGGGGAGGACGAGGAGTGGACAGACAAGGCCCGGCGGGTCATCATGGAGCGTATCGGCCTCGCCACTGCAGGGGAG
CCCTACCACGACATCCGCTTCAACCTGATGGCAGTGGTGCCCGACCGCAGGATCAAGTATGAGGCCAGGCTGCATGTGCTGAAGGTGAAC
CGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGATAAGAGTAACACAGCCAGAGCTGATTCAGACCCACAAGTCTCAAGAGTCACAGCTG
CCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCCGCTGGTGCTGGAAGCAAACAGGGCCCCTGCAGCCTCTGAGGGCAACCACACAGAT
GGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGCCCCATCCCACAGCCCTCCCAACAAACCCAAGCTAGTGGTGAAGCCTCCAGGCAGC
AGCCTCAATGGGGTTCACCCCAACCCCACTCCCATTGTCCAGCGGCTGCCGGCCTTTCTAGACAATCACAATTATGCCAAGTCCCCCATG
CAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCGCAGCCGAGTTCCAGTCCGCCCACCCCAGCAGTACTCAGATGATGAGGATGACTAT
GAGGATGACGAGGAGGATGACGTGCAGAACACCAACTCTGCCCTTAGGTATAAGGGGAAGGGAACAGGGAAGCCAGGGGCATTGAGCGGT
TCTGCTGATGGGCAACTGTCAGTGCTGCAGCCCAACACCATCAACGTCTTGGCTGAGAAGCTCAAAGAGTCCCAGAAGGACCTCTCAATT
CCTCTGTCCATCAAGACTAGCAGCGGGGCTGGGAGTCCGGCTGTGGCAGTGCCCACACACTCGCAGCCCTCACCCACCCCCAGCAATGAG
AGTACAGACACGGCCTCTGAGATCGGCAGTGCTTTCAACTCGCCACTGCGCTCGCCTATCCGCTCAGCCAACCCGACGCGGCCCTCCAGC
CCTGTCACCTCCCACATCTCCAAGGTGCTTTTTGGAGAGGATGACAGCCTGCTGCGTGTTGACTGCATACGCTACAACCGTGCTGTCCGT
GATCTGGGTCCTGTCATCAGCACAGGCCTGCTGCACCTGGCTGAGGATGGGGTGCTGAGTCCCCTGGCGCTGACAGAGGGTGGGAAGGGT
TCCTCGCCCTCCATCAGACCAATCCAAGGCAGCCAGGGGTCCAGCAGCCCAGTGGAGAAGGAGGTCGTGGAAGCCACGGACAGCAGAGAG
AAGACGGGGATGGTGAGGCCTGGCGAGCCCTTGAGTGGGGAGAAATACTCACCCAAGGAGCTGCTGGCACTGCTGAAGTGTGTGGAGGCT
GAGATTGCAAACTATGAGGCGTGCCTCAAGGAGGAGGTAGAGAAGAGGAAGAAGTTCAAGATTGATGACCAGAGAAGGACCCACAACTAC
GATGAGTTCATCTGCACCTTTATCTCCATGCTGGCTCAGGAAGGCATGCTGGCCAACCTAGTGGAGCAGAACATCTCCGTGCGGCGGCGC
CAAGGGGTCAGCATCGGCCGGCTCCACAAGCAGCGGAAGCCTGACCGGCGGAAACGCTCTCGCCCCTACAAGGCCAAGCGCCAGTGAGGA
CTGCTGGCCCTGACTCTGCAGCCCACTCTTGCCGTGTGGCCCTCACCAGGGTCCTTCCCTGCCCCACTTCCCCTTTTCCCAGTATTACTG
AATAGTCCCAGCTGGAGAGTCCAGGCCCTGGGAATGGGAGGAACCAGGCCACATTCCTTCCATCGTGCCCTGAGGCCTGACACGGCAGAT
CAGCCCCATAGTGCTCAGGAGGCAGCATCTGGAGTTGGGGCACAGCGAGGTACTGCAGCTTCCTCCACAGCCGGCTGTGGAGCAGCAGGA
CCTGGCCCTTCTGCCTGGGCAGCAGAATATATATTTTACCTATCAGAGACATCTATTTTTCTGGGCTCCAACCCAACATGCCACCATGTT
GACATAAGTTCCTACCTGACTATGCTTTCTCTCCTAGGAGCTGTCCTGGTGGGCCCAGGTCCTTGTATCATGCCACGGTCCCAACTACAG
GGTCCTAGCTGGGGGCCTGGGTGGGCCCTGGGCTCTGGGCCCTGCTGCTCTAGCCCCAGCCACCAGCCTGTCCCTGTTGTAAGGAAGCCA
GGTCTTCTCTCTTCATTCCTCTTAGGAGAGTGCCAAACTCAGGGACCCAGCACTGGGCTGGGTTGGGAGTAGGGTGTCCCAGTGGGGTTG
GGGTGAGCAGGCTGCTGGGATCCCATGGCCTGAGCAGAGCATGTGGGAACTGTTCAGTGGCCTGTGAACTGTCTTCCTTGTTCTAGCCAG
GCTGTTCAAGACTGCTCTCCATAGCAAGGTTCTAGGGCTCTTCGCCTTCAGTGTTGTGGCCCTAGCTATGGGCCTAAATTGGGCTCTAGG
TCTCTGTCCCTGGCGCTTGAGGCTCAGAAGAGCCTCTGTCCAGCCCCTCAGTATTACCATGTCTCCCTCTCAGGGGTAGCAGAGACAGGG
TTGCTTATAGGAAGCTGGCACCACTCAGCTCTTCCTGCTACTCCAGTTTCCTCAGCCTCTGCAAGGCACTCAGGGTGGGGGACAGCAGGA
TCAAGACAACCCGTTGGAGCCCCTGTGTTCCAGAGGACCTGATGCCAAGGGGTAATGGGCCCAGCAGTGCCTCTGGAGCCCAGGCCCCAA
CACAGCCCCATGGCCTCTGCCAGATGGCTTTGAAAAAGGTGATCCAAGCAGGCCCCTTTATCTGTACATAGTGACTGAGTGGGGGGTGCT
GGCAAGTGTGGCAGCTGCCTCTGGGCTGAGCACAGCTTGACCCCTCTAGCCCCTGTAAATACTGGATCAATGAATGAATAAAACTCTCCT

>1916_1916_4_ACY1-BAP1_ACY1_chr3_52021640_ENST00000458031_BAP1_chr3_52441476_ENST00000460680_length(amino acids)=1001AA_BP=397
MWGCQAPLSRLPASGETPMSQSWLVSPLATRPSFTARCSHSTRHTGWRWCCFMERPLTLTRGSSWAHCSYCHRGATGPWPLTFQLTTRSA
MTSKGPEEEHPSVTLFRQYLRIRTVQPKPDYGAAVAFFEETARQLGLGCQKVEVAPGYVVTVLTWPGTNPTLSSILLNSHTDVVPVFKEH
WSHDPFEAFKDSEGYIYARGAQDMKCVSIQYLEAVRRLKVEGHRFPRTIHMTFVPDEEVGGHQGMELFVQRPEFHALRAGFALDEGIANP
TDAFTVFYSERSPWWVRVTSTGRPGHASRFMEDTAAEKLHKVVNSILAFREKEWQRLQSNPHLKEGSVTSVNLTKLEGGVAYNVIPATMS
ASFDFRVAPDVDFKAFEEQLQSWCQAAGEGVTLEFAQSKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITG
RLFELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRIKYEARLHVLKVNRQTVLEALQQLIRVTQP
ELIQTHKSQESQLPEESKSASNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLP
AFLDNHNYAKSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRYKGKGTGKPGALSGSADGQLSVLQPNTINVL
AEKLKESQKDLSIPLSIKTSSGAGSPAVAVPTHSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSL
LRVDCIRYNRAVRDLGPVISTGLLHLAEDGVLSPLALTEGGKGSSPSIRPIQGSQGSSSPVEKEVVEATDSREKTGMVRPGEPLSGEKYS
PKELLALLKCVEAEIANYEACLKEEVEKRKKFKIDDQRRTHNYDEFICTFISMLAQEGMLANLVEQNISVRRRQGVSIGRLHKQRKPDRR

--------------------------------------------------------------
>1916_1916_5_ACY1-BAP1_ACY1_chr3_52021640_ENST00000476351_BAP1_chr3_52441476_ENST00000296288_length(transcript)=4004nt_BP=981nt
CGACATCCGGCCTCGGCCACGTGGTGGGCGGACCGGGGCGGTCCTGAGCCTGCGACCTCGCAGGCGACCTCGCTGGACCCTAAGTCCAGG
CCACAGTCAGGGAAGGGCGCTGAGAGGCGAGCGTGAGCCCAGCGACAGGAGAGTGAGCTCACCACGCGCAGCGCCATGACCAGCAAGGGT
CCCGAGGAGGAGCACCCATCGGTGACGCTCTTCCGCCAGTACCTGCGTATCCGCACTGTCCAGCCCAAGCCTGACTATGGCACCAACCCT
ACACTCTCCTCCATCTTGCTCAACTCCCACACGGATGTGGTGCCTGTCTTCAAGGAACATTGGAGTCACGACCCCTTTGAGGCCTTCAAG
GATTCTGAGGGCTACATCTATGCCAGGGGTGCCCAGGACATGAAGTGCGTCAGCATCCAGTACCTGGAAGCTGTGAGGAGGCTGAAGGTG
GAGGGCCACCGGTTCCCCAGAACCATCCACATGACCTTTGTGCCTGATGAGGAGGTTGGGGGTCACCAAGGCATGGAGCTGTTCGTGCAG
CGGCCTGAGTTCCACGCCCTGAGGGCAGGCTTTGCCCTGGATGAGGGCATAGCCAATCCCACTGATGCCTTCACTGTCTTTTATAGTGAG
CGGAGTCCCTGGTGGGTGCGGGTTACCAGCACTGGGAGGCCAGGCCATGCCTCACGCTTCATGGAGGACACAGCAGCAGAGAAGCTGCAC
AAGGTTGTAAACTCCATCCTGGCATTCCGGGAGAAGGAATGGCAGAGGCTGCAGTCAAACCCCCACCTGAAAGAGGGGTCCGTGACCTCC
GTGAACCTGACTAAGCTAGAGGGTGGCGTGGCCTATAACGTGATACCTGCCACCATGAGCGCCAGCTTTGACTTCCGTGTGGCACCGGAT
GTGGACTTCAAGGCTTTTGAGGAGCAGCTGCAGAGCTGGTGCCAGGCAGCTGGCGAGGGGGTCACCCTAGAGTTTGCTCAGAGCAAAGGA
TATGCGATTGGCAATGCCCCGGAGTTGGCCAAGGCCCATAATAGCCATGCCAGGCCCGAGCCACGCCACCTCCCTGAGAAGCAGAATGGC
CTTAGTGCAGTGCGGACCATGGAGGCGTTCCACTTTGTCAGCTATGTGCCTATCACAGGCCGGCTCTTTGAGCTGGATGGGCTGAAGGTC
TACCCCATTGACCATGGGCCCTGGGGGGAGGACGAGGAGTGGACAGACAAGGCCCGGCGGGTCATCATGGAGCGTATCGGCCTCGCCACT
GCAGGGATCAAGTATGAGGCCAGGCTGCATGTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGATAAGAGTAACA
CAGCCAGAGCTGATTCAGACCCACAAGTCTCAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCCGCTGGTGCTG
GAAGCAAACAGGGCCCCTGCAGCCTCTGAGGGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGCCCCATCCCAC
AGCCCTCCCAACAAACCCAAGCTAGTGGTGAAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCATTGTCCAGCGG
CTGCCGGCCTTTCTAGACAATCACAATTATGCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCGCAGCCGAGTT
CCAGTCCGCCCACCCCAGCAGTACTCAGATGATGAGGATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAACTCTGCCCTT
AGGTATAAGGGGAAGGGAACAGGGAAGCCAGGGGCATTGAGCGGTTCTGCTGATGGGCAACTGTCAGTGCTGCAGCCCAACACCATCAAC
GTCTTGGCTGAGAAGCTCAAAGAGTCCCAGAAGGACCTCTCAATTCCTCTGTCCATCAAGACTAGCAGCGGGGCTGGGAGTCCGGCTGTG
GCAGTGCCCACACACTCGCAGCCCTCACCCACCCCCAGCAATGAGAGTACAGACACGGCCTCTGAGATCGGCAGTGCTTTCAACTCGCCA
CTGCGCTCGCCTATCCGCTCAGCCAACCCGACGCGGCCCTCCAGCCCTGTCACCTCCCACATCTCCAAGGTGCTTTTTGGAGAGGATGAC
AGCCTGCTGCGTGTTGACTGCATACGCTACAACCGTGCTGTCCGTGATCTGGGTCCTGTCATCAGCACAGGCCTGCTGCACCTGGCTGAG
GATGGGGTGCTGAGTCCCCTGGCGCTGACAGAGGGTGGGAAGGGTTCCTCGCCCTCCATCAGACCAATCCAAGGCAGCCAGGGGTCCAGC
AGCCCAGTGGAGAAGGAGGTCGTGGAAGCCACGGACAGCAGAGAGAAGACGGGGATGGTGAGGCCTGGCGAGCCCTTGAGTGGGGAGAAA
TACTCACCCAAGGAGCTGCTGGCACTGCTGAAGTGTGTGGAGGCTGAGATTGCAAACTATGAGGCGTGCCTCAAGGAGGAGGTAGAGAAG
AGGAAGAAGTTCAAGATTGATGACCAGAGAAGGACCCACAACTACGATGAGTTCATCTGCACCTTTATCTCCATGCTGGCTCAGGAAGGC
ATGCTGGCCAACCTAGTGGAGCAGAACATCTCCGTGCGGCGGCGCCAAGGGGTCAGCATCGGCCGGCTCCACAAGCAGCGGAAGCCTGAC
CGGCGGAAACGCTCTCGCCCCTACAAGGCCAAGCGCCAGTGAGGACTGCTGGCCCTGACTCTGCAGCCCACTCTTGCCGTGTGGCCCTCA
CCAGGGTCCTTCCCTGCCCCACTTCCCCTTTTCCCAGTATTACTGAATAGTCCCAGCTGGAGAGTCCAGGCCCTGGGAATGGGAGGAACC
AGGCCACATTCCTTCCATCGTGCCCTGAGGCCTGACACGGCAGATCAGCCCCATAGTGCTCAGGAGGCAGCATCTGGAGTTGGGGCACAG
CGAGGTACTGCAGCTTCCTCCACAGCCGGCTGTGGAGCAGCAGGACCTGGCCCTTCTGCCTGGGCAGCAGAATATATATTTTACCTATCA
GAGACATCTATTTTTCTGGGCTCCAACCCAACATGCCACCATGTTGACATAAGTTCCTACCTGACTATGCTTTCTCTCCTAGGAGCTGTC
CTGGTGGGCCCAGGTCCTTGTATCATGCCACGGTCCCAACTACAGGGTCCTAGCTGGGGGCCTGGGTGGGCCCTGGGCTCTGGGCCCTGC
TGCTCTAGCCCCAGCCACCAGCCTGTCCCTGTTGTAAGGAAGCCAGGTCTTCTCTCTTCATTCCTCTTAGGAGAGTGCCAAACTCAGGGA
CCCAGCACTGGGCTGGGTTGGGAGTAGGGTGTCCCAGTGGGGTTGGGGTGAGCAGGCTGCTGGGATCCCATGGCCTGAGCAGAGCATGTG
GGAACTGTTCAGTGGCCTGTGAACTGTCTTCCTTGTTCTAGCCAGGCTGTTCAAGACTGCTCTCCATAGCAAGGTTCTAGGGCTCTTCGC
CTTCAGTGTTGTGGCCCTAGCTATGGGCCTAAATTGGGCTCTAGGTCTCTGTCCCTGGCGCTTGAGGCTCAGAAGAGCCTCTGTCCAGCC
CCTCAGTATTACCATGTCTCCCTCTCAGGGGTAGCAGAGACAGGGTTGCTTATAGGAAGCTGGCACCACTCAGCTCTTCCTGCTACTCCA
GTTTCCTCAGCCTCTGCAAGGCACTCAGGGTGGGGGACAGCAGGATCAAGACAACCCGTTGGAGCCCCTGTGTTCCAGAGGACCTGATGC
CAAGGGGTAATGGGCCCAGCAGTGCCTCTGGAGCCCAGGCCCCAACACAGCCCCATGGCCTCTGCCAGATGGCTTTGAAAAAGGTGATCC
AAGCAGGCCCCTTTATCTGTACATAGTGACTGAGTGGGGGGTGCTGGCAAGTGTGGCAGCTGCCTCTGGGCTGAGCACAGCTTGACCCCT

>1916_1916_5_ACY1-BAP1_ACY1_chr3_52021640_ENST00000476351_BAP1_chr3_52441476_ENST00000296288_length(amino acids)=858AA_BP=272
MTSKGPEEEHPSVTLFRQYLRIRTVQPKPDYGTNPTLSSILLNSHTDVVPVFKEHWSHDPFEAFKDSEGYIYARGAQDMKCVSIQYLEAV
RRLKVEGHRFPRTIHMTFVPDEEVGGHQGMELFVQRPEFHALRAGFALDEGIANPTDAFTVFYSERSPWWVRVTSTGRPGHASRFMEDTA
AEKLHKVVNSILAFREKEWQRLQSNPHLKEGSVTSVNLTKLEGGVAYNVIPATMSASFDFRVAPDVDFKAFEEQLQSWCQAAGEGVTLEF
AQSKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRLFELDGLKVYPIDHGPWGEDEEWTDKARRVIMER
IGLATAGIKYEARLHVLKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKSASNKSPLVLEANRAPAASEGNHTDGAEEAAGSCA
QAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAFLDNHNYAKSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQN
TNSALRYKGKGTGKPGALSGSADGQLSVLQPNTINVLAEKLKESQKDLSIPLSIKTSSGAGSPAVAVPTHSQPSPTPSNESTDTASEIGS
AFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSLLRVDCIRYNRAVRDLGPVISTGLLHLAEDGVLSPLALTEGGKGSSPSIRPIQG
SQGSSSPVEKEVVEATDSREKTGMVRPGEPLSGEKYSPKELLALLKCVEAEIANYEACLKEEVEKRKKFKIDDQRRTHNYDEFICTFISM

--------------------------------------------------------------
>1916_1916_6_ACY1-BAP1_ACY1_chr3_52021640_ENST00000476351_BAP1_chr3_52441476_ENST00000460680_length(transcript)=4071nt_BP=981nt
CGACATCCGGCCTCGGCCACGTGGTGGGCGGACCGGGGCGGTCCTGAGCCTGCGACCTCGCAGGCGACCTCGCTGGACCCTAAGTCCAGG
CCACAGTCAGGGAAGGGCGCTGAGAGGCGAGCGTGAGCCCAGCGACAGGAGAGTGAGCTCACCACGCGCAGCGCCATGACCAGCAAGGGT
CCCGAGGAGGAGCACCCATCGGTGACGCTCTTCCGCCAGTACCTGCGTATCCGCACTGTCCAGCCCAAGCCTGACTATGGCACCAACCCT
ACACTCTCCTCCATCTTGCTCAACTCCCACACGGATGTGGTGCCTGTCTTCAAGGAACATTGGAGTCACGACCCCTTTGAGGCCTTCAAG
GATTCTGAGGGCTACATCTATGCCAGGGGTGCCCAGGACATGAAGTGCGTCAGCATCCAGTACCTGGAAGCTGTGAGGAGGCTGAAGGTG
GAGGGCCACCGGTTCCCCAGAACCATCCACATGACCTTTGTGCCTGATGAGGAGGTTGGGGGTCACCAAGGCATGGAGCTGTTCGTGCAG
CGGCCTGAGTTCCACGCCCTGAGGGCAGGCTTTGCCCTGGATGAGGGCATAGCCAATCCCACTGATGCCTTCACTGTCTTTTATAGTGAG
CGGAGTCCCTGGTGGGTGCGGGTTACCAGCACTGGGAGGCCAGGCCATGCCTCACGCTTCATGGAGGACACAGCAGCAGAGAAGCTGCAC
AAGGTTGTAAACTCCATCCTGGCATTCCGGGAGAAGGAATGGCAGAGGCTGCAGTCAAACCCCCACCTGAAAGAGGGGTCCGTGACCTCC
GTGAACCTGACTAAGCTAGAGGGTGGCGTGGCCTATAACGTGATACCTGCCACCATGAGCGCCAGCTTTGACTTCCGTGTGGCACCGGAT
GTGGACTTCAAGGCTTTTGAGGAGCAGCTGCAGAGCTGGTGCCAGGCAGCTGGCGAGGGGGTCACCCTAGAGTTTGCTCAGAGCAAAGGA
TATGCGATTGGCAATGCCCCGGAGTTGGCCAAGGCCCATAATAGCCATGCCAGGCCCGAGCCACGCCACCTCCCTGAGAAGCAGAATGGC
CTTAGTGCAGTGCGGACCATGGAGGCGTTCCACTTTGTCAGCTATGTGCCTATCACAGGCCGGCTCTTTGAGCTGGATGGGCTGAAGGTC
TACCCCATTGACCATGGGCCCTGGGGGGAGGACGAGGAGTGGACAGACAAGGCCCGGCGGGTCATCATGGAGCGTATCGGCCTCGCCACT
GCAGGGGAGCCCTACCACGACATCCGCTTCAACCTGATGGCAGTGGTGCCCGACCGCAGGATCAAGTATGAGGCCAGGCTGCATGTGCTG
AAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGATAAGAGTAACACAGCCAGAGCTGATTCAGACCCACAAGTCTCAAGAG
TCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCCGCTGGTGCTGGAAGCAAACAGGGCCCCTGCAGCCTCTGAGGGCAAC
CACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGCCCCATCCCACAGCCCTCCCAACAAACCCAAGCTAGTGGTGAAGCCT
CCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCATTGTCCAGCGGCTGCCGGCCTTTCTAGACAATCACAATTATGCCAAG
TCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCGCAGCCGAGTTCCAGTCCGCCCACCCCAGCAGTACTCAGATGATGAG
GATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAACTCTGCCCTTAGGTATAAGGGGAAGGGAACAGGGAAGCCAGGGGCA
TTGAGCGGTTCTGCTGATGGGCAACTGTCAGTGCTGCAGCCCAACACCATCAACGTCTTGGCTGAGAAGCTCAAAGAGTCCCAGAAGGAC
CTCTCAATTCCTCTGTCCATCAAGACTAGCAGCGGGGCTGGGAGTCCGGCTGTGGCAGTGCCCACACACTCGCAGCCCTCACCCACCCCC
AGCAATGAGAGTACAGACACGGCCTCTGAGATCGGCAGTGCTTTCAACTCGCCACTGCGCTCGCCTATCCGCTCAGCCAACCCGACGCGG
CCCTCCAGCCCTGTCACCTCCCACATCTCCAAGGTGCTTTTTGGAGAGGATGACAGCCTGCTGCGTGTTGACTGCATACGCTACAACCGT
GCTGTCCGTGATCTGGGTCCTGTCATCAGCACAGGCCTGCTGCACCTGGCTGAGGATGGGGTGCTGAGTCCCCTGGCGCTGACAGAGGGT
GGGAAGGGTTCCTCGCCCTCCATCAGACCAATCCAAGGCAGCCAGGGGTCCAGCAGCCCAGTGGAGAAGGAGGTCGTGGAAGCCACGGAC
AGCAGAGAGAAGACGGGGATGGTGAGGCCTGGCGAGCCCTTGAGTGGGGAGAAATACTCACCCAAGGAGCTGCTGGCACTGCTGAAGTGT
GTGGAGGCTGAGATTGCAAACTATGAGGCGTGCCTCAAGGAGGAGGTAGAGAAGAGGAAGAAGTTCAAGATTGATGACCAGAGAAGGACC
CACAACTACGATGAGTTCATCTGCACCTTTATCTCCATGCTGGCTCAGGAAGGCATGCTGGCCAACCTAGTGGAGCAGAACATCTCCGTG
CGGCGGCGCCAAGGGGTCAGCATCGGCCGGCTCCACAAGCAGCGGAAGCCTGACCGGCGGAAACGCTCTCGCCCCTACAAGGCCAAGCGC
CAGTGAGGACTGCTGGCCCTGACTCTGCAGCCCACTCTTGCCGTGTGGCCCTCACCAGGGTCCTTCCCTGCCCCACTTCCCCTTTTCCCA
GTATTACTGAATAGTCCCAGCTGGAGAGTCCAGGCCCTGGGAATGGGAGGAACCAGGCCACATTCCTTCCATCGTGCCCTGAGGCCTGAC
ACGGCAGATCAGCCCCATAGTGCTCAGGAGGCAGCATCTGGAGTTGGGGCACAGCGAGGTACTGCAGCTTCCTCCACAGCCGGCTGTGGA
GCAGCAGGACCTGGCCCTTCTGCCTGGGCAGCAGAATATATATTTTACCTATCAGAGACATCTATTTTTCTGGGCTCCAACCCAACATGC
CACCATGTTGACATAAGTTCCTACCTGACTATGCTTTCTCTCCTAGGAGCTGTCCTGGTGGGCCCAGGTCCTTGTATCATGCCACGGTCC
CAACTACAGGGTCCTAGCTGGGGGCCTGGGTGGGCCCTGGGCTCTGGGCCCTGCTGCTCTAGCCCCAGCCACCAGCCTGTCCCTGTTGTA
AGGAAGCCAGGTCTTCTCTCTTCATTCCTCTTAGGAGAGTGCCAAACTCAGGGACCCAGCACTGGGCTGGGTTGGGAGTAGGGTGTCCCA
GTGGGGTTGGGGTGAGCAGGCTGCTGGGATCCCATGGCCTGAGCAGAGCATGTGGGAACTGTTCAGTGGCCTGTGAACTGTCTTCCTTGT
TCTAGCCAGGCTGTTCAAGACTGCTCTCCATAGCAAGGTTCTAGGGCTCTTCGCCTTCAGTGTTGTGGCCCTAGCTATGGGCCTAAATTG
GGCTCTAGGTCTCTGTCCCTGGCGCTTGAGGCTCAGAAGAGCCTCTGTCCAGCCCCTCAGTATTACCATGTCTCCCTCTCAGGGGTAGCA
GAGACAGGGTTGCTTATAGGAAGCTGGCACCACTCAGCTCTTCCTGCTACTCCAGTTTCCTCAGCCTCTGCAAGGCACTCAGGGTGGGGG
ACAGCAGGATCAAGACAACCCGTTGGAGCCCCTGTGTTCCAGAGGACCTGATGCCAAGGGGTAATGGGCCCAGCAGTGCCTCTGGAGCCC
AGGCCCCAACACAGCCCCATGGCCTCTGCCAGATGGCTTTGAAAAAGGTGATCCAAGCAGGCCCCTTTATCTGTACATAGTGACTGAGTG
GGGGGTGCTGGCAAGTGTGGCAGCTGCCTCTGGGCTGAGCACAGCTTGACCCCTCTAGCCCCTGTAAATACTGGATCAATGAATGAATAA

>1916_1916_6_ACY1-BAP1_ACY1_chr3_52021640_ENST00000476351_BAP1_chr3_52441476_ENST00000460680_length(amino acids)=876AA_BP=272
MTSKGPEEEHPSVTLFRQYLRIRTVQPKPDYGTNPTLSSILLNSHTDVVPVFKEHWSHDPFEAFKDSEGYIYARGAQDMKCVSIQYLEAV
RRLKVEGHRFPRTIHMTFVPDEEVGGHQGMELFVQRPEFHALRAGFALDEGIANPTDAFTVFYSERSPWWVRVTSTGRPGHASRFMEDTA
AEKLHKVVNSILAFREKEWQRLQSNPHLKEGSVTSVNLTKLEGGVAYNVIPATMSASFDFRVAPDVDFKAFEEQLQSWCQAAGEGVTLEF
AQSKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLSAVRTMEAFHFVSYVPITGRLFELDGLKVYPIDHGPWGEDEEWTDKARRVIMER
IGLATAGEPYHDIRFNLMAVVPDRRIKYEARLHVLKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKSASNKSPLVLEANRAPA
ASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLPAFLDNHNYAKSPMQEEEDLAAGVGRSRVPVRPPQQ
YSDDEDDYEDDEEDDVQNTNSALRYKGKGTGKPGALSGSADGQLSVLQPNTINVLAEKLKESQKDLSIPLSIKTSSGAGSPAVAVPTHSQ
PSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSLLRVDCIRYNRAVRDLGPVISTGLLHLAEDGVLSPL
ALTEGGKGSSPSIRPIQGSQGSSSPVEKEVVEATDSREKTGMVRPGEPLSGEKYSPKELLALLKCVEAEIANYEACLKEEVEKRKKFKID

--------------------------------------------------------------
>1916_1916_7_ACY1-BAP1_ACY1_chr3_52021640_ENST00000476854_BAP1_chr3_52441476_ENST00000296288_length(transcript)=3914nt_BP=891nt
CGACATCCGGCCTCGGCCACGTGGTGGGCGGACCGGGGCGGTCCTGAGCCTGCGACCTCGCAGGCGACCTCGCTGGACCCTAAGTCCAGG
CCACAGTCAGGGAAGGGCGCTGAGAGGCGAGCGTGAGCCCAGCGACAGGAGAGTGAGCTCACCACGCGCAGCGCCATGACCAGCAAGGGT
CCCGAGGAGGAGCACCCATCGGTGACGCTCTTCCGCCAGTACCTGCGTATCCGCACTGTCCAGCCCAAGCCTGACTATGGAGCTGCTGTG
GCTTTCTTTGAGGAGACAGCCCGCCAGCTGGGCCTGGGCTGTCAGAAAGTAGAGGTGGCACCTGGCTATGTGGTGACCGTGTTGACCTGG
CCAGGCACCAACCCTACACTCTCCTCCATCTTGCTCAACTCCCACACGGATGTGGTGCCTGTCTTCAAGGAACATTGGAGTCACGACCCC
TTTGAGGCCTTCAAGGATTCTGAGGGCTACATCTATGCCAGGGGTGCCCAGGACATGAAGTGCGTCAGCATCCAGTACCTGGAAGCTGTG
AGGAGGCTGAAGGTGGAGGGCCACCGGTTCCCCAGAACCATCCACATGACCTTTGTGCCTGATGAGGAGGTTGGGGGTCACCAAGGCATG
GAGCTGTTCGTGCAGCGGCCTGAGTTCCACGCCCTGAGGGCAGGCTTTGCCCTGGATGAGGGCATAGCCAATCCCACTGATGCCTTCACT
GTCTTTTATAGTGAGCGGAGTCCCTGGTGGGTGCGGGTTACCAGCACTGGGAGGCCAGGCCATGCCTCACGCTTCATGGAGGACACAGCA
GCAGAGAAGCTGGCTTTTGAGGAGCAGCTGCAGAGCTGGTGCCAGGCAGCTGGCGAGGGGGTCACCCTAGAGTTTGCTCAGAGCAAAGGA
TATGCGATTGGCAATGCCCCGGAGTTGGCCAAGGCCCATAATAGCCATGCCAGGCCCGAGCCACGCCACCTCCCTGAGAAGCAGAATGGC
CTTAGTGCAGTGCGGACCATGGAGGCGTTCCACTTTGTCAGCTATGTGCCTATCACAGGCCGGCTCTTTGAGCTGGATGGGCTGAAGGTC
TACCCCATTGACCATGGGCCCTGGGGGGAGGACGAGGAGTGGACAGACAAGGCCCGGCGGGTCATCATGGAGCGTATCGGCCTCGCCACT
GCAGGGATCAAGTATGAGGCCAGGCTGCATGTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGATAAGAGTAACA
CAGCCAGAGCTGATTCAGACCCACAAGTCTCAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCCGCTGGTGCTG
GAAGCAAACAGGGCCCCTGCAGCCTCTGAGGGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGCCCCATCCCAC
AGCCCTCCCAACAAACCCAAGCTAGTGGTGAAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCATTGTCCAGCGG
CTGCCGGCCTTTCTAGACAATCACAATTATGCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCGCAGCCGAGTT
CCAGTCCGCCCACCCCAGCAGTACTCAGATGATGAGGATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAACTCTGCCCTT
AGGTATAAGGGGAAGGGAACAGGGAAGCCAGGGGCATTGAGCGGTTCTGCTGATGGGCAACTGTCAGTGCTGCAGCCCAACACCATCAAC
GTCTTGGCTGAGAAGCTCAAAGAGTCCCAGAAGGACCTCTCAATTCCTCTGTCCATCAAGACTAGCAGCGGGGCTGGGAGTCCGGCTGTG
GCAGTGCCCACACACTCGCAGCCCTCACCCACCCCCAGCAATGAGAGTACAGACACGGCCTCTGAGATCGGCAGTGCTTTCAACTCGCCA
CTGCGCTCGCCTATCCGCTCAGCCAACCCGACGCGGCCCTCCAGCCCTGTCACCTCCCACATCTCCAAGGTGCTTTTTGGAGAGGATGAC
AGCCTGCTGCGTGTTGACTGCATACGCTACAACCGTGCTGTCCGTGATCTGGGTCCTGTCATCAGCACAGGCCTGCTGCACCTGGCTGAG
GATGGGGTGCTGAGTCCCCTGGCGCTGACAGAGGGTGGGAAGGGTTCCTCGCCCTCCATCAGACCAATCCAAGGCAGCCAGGGGTCCAGC
AGCCCAGTGGAGAAGGAGGTCGTGGAAGCCACGGACAGCAGAGAGAAGACGGGGATGGTGAGGCCTGGCGAGCCCTTGAGTGGGGAGAAA
TACTCACCCAAGGAGCTGCTGGCACTGCTGAAGTGTGTGGAGGCTGAGATTGCAAACTATGAGGCGTGCCTCAAGGAGGAGGTAGAGAAG
AGGAAGAAGTTCAAGATTGATGACCAGAGAAGGACCCACAACTACGATGAGTTCATCTGCACCTTTATCTCCATGCTGGCTCAGGAAGGC
ATGCTGGCCAACCTAGTGGAGCAGAACATCTCCGTGCGGCGGCGCCAAGGGGTCAGCATCGGCCGGCTCCACAAGCAGCGGAAGCCTGAC
CGGCGGAAACGCTCTCGCCCCTACAAGGCCAAGCGCCAGTGAGGACTGCTGGCCCTGACTCTGCAGCCCACTCTTGCCGTGTGGCCCTCA
CCAGGGTCCTTCCCTGCCCCACTTCCCCTTTTCCCAGTATTACTGAATAGTCCCAGCTGGAGAGTCCAGGCCCTGGGAATGGGAGGAACC
AGGCCACATTCCTTCCATCGTGCCCTGAGGCCTGACACGGCAGATCAGCCCCATAGTGCTCAGGAGGCAGCATCTGGAGTTGGGGCACAG
CGAGGTACTGCAGCTTCCTCCACAGCCGGCTGTGGAGCAGCAGGACCTGGCCCTTCTGCCTGGGCAGCAGAATATATATTTTACCTATCA
GAGACATCTATTTTTCTGGGCTCCAACCCAACATGCCACCATGTTGACATAAGTTCCTACCTGACTATGCTTTCTCTCCTAGGAGCTGTC
CTGGTGGGCCCAGGTCCTTGTATCATGCCACGGTCCCAACTACAGGGTCCTAGCTGGGGGCCTGGGTGGGCCCTGGGCTCTGGGCCCTGC
TGCTCTAGCCCCAGCCACCAGCCTGTCCCTGTTGTAAGGAAGCCAGGTCTTCTCTCTTCATTCCTCTTAGGAGAGTGCCAAACTCAGGGA
CCCAGCACTGGGCTGGGTTGGGAGTAGGGTGTCCCAGTGGGGTTGGGGTGAGCAGGCTGCTGGGATCCCATGGCCTGAGCAGAGCATGTG
GGAACTGTTCAGTGGCCTGTGAACTGTCTTCCTTGTTCTAGCCAGGCTGTTCAAGACTGCTCTCCATAGCAAGGTTCTAGGGCTCTTCGC
CTTCAGTGTTGTGGCCCTAGCTATGGGCCTAAATTGGGCTCTAGGTCTCTGTCCCTGGCGCTTGAGGCTCAGAAGAGCCTCTGTCCAGCC
CCTCAGTATTACCATGTCTCCCTCTCAGGGGTAGCAGAGACAGGGTTGCTTATAGGAAGCTGGCACCACTCAGCTCTTCCTGCTACTCCA
GTTTCCTCAGCCTCTGCAAGGCACTCAGGGTGGGGGACAGCAGGATCAAGACAACCCGTTGGAGCCCCTGTGTTCCAGAGGACCTGATGC
CAAGGGGTAATGGGCCCAGCAGTGCCTCTGGAGCCCAGGCCCCAACACAGCCCCATGGCCTCTGCCAGATGGCTTTGAAAAAGGTGATCC
AAGCAGGCCCCTTTATCTGTACATAGTGACTGAGTGGGGGGTGCTGGCAAGTGTGGCAGCTGCCTCTGGGCTGAGCACAGCTTGACCCCT

>1916_1916_7_ACY1-BAP1_ACY1_chr3_52021640_ENST00000476854_BAP1_chr3_52441476_ENST00000296288_length(amino acids)=828AA_BP=242
MTSKGPEEEHPSVTLFRQYLRIRTVQPKPDYGAAVAFFEETARQLGLGCQKVEVAPGYVVTVLTWPGTNPTLSSILLNSHTDVVPVFKEH
WSHDPFEAFKDSEGYIYARGAQDMKCVSIQYLEAVRRLKVEGHRFPRTIHMTFVPDEEVGGHQGMELFVQRPEFHALRAGFALDEGIANP
TDAFTVFYSERSPWWVRVTSTGRPGHASRFMEDTAAEKLAFEEQLQSWCQAAGEGVTLEFAQSKGYAIGNAPELAKAHNSHARPEPRHLP
EKQNGLSAVRTMEAFHFVSYVPITGRLFELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGIKYEARLHVLKVNRQTVLEALQQ
LIRVTQPELIQTHKSQESQLPEESKSASNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPT
PIVQRLPAFLDNHNYAKSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRYKGKGTGKPGALSGSADGQLSVLQ
PNTINVLAEKLKESQKDLSIPLSIKTSSGAGSPAVAVPTHSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVL
FGEDDSLLRVDCIRYNRAVRDLGPVISTGLLHLAEDGVLSPLALTEGGKGSSPSIRPIQGSQGSSSPVEKEVVEATDSREKTGMVRPGEP
LSGEKYSPKELLALLKCVEAEIANYEACLKEEVEKRKKFKIDDQRRTHNYDEFICTFISMLAQEGMLANLVEQNISVRRRQGVSIGRLHK

--------------------------------------------------------------
>1916_1916_8_ACY1-BAP1_ACY1_chr3_52021640_ENST00000476854_BAP1_chr3_52441476_ENST00000460680_length(transcript)=3981nt_BP=891nt
CGACATCCGGCCTCGGCCACGTGGTGGGCGGACCGGGGCGGTCCTGAGCCTGCGACCTCGCAGGCGACCTCGCTGGACCCTAAGTCCAGG
CCACAGTCAGGGAAGGGCGCTGAGAGGCGAGCGTGAGCCCAGCGACAGGAGAGTGAGCTCACCACGCGCAGCGCCATGACCAGCAAGGGT
CCCGAGGAGGAGCACCCATCGGTGACGCTCTTCCGCCAGTACCTGCGTATCCGCACTGTCCAGCCCAAGCCTGACTATGGAGCTGCTGTG
GCTTTCTTTGAGGAGACAGCCCGCCAGCTGGGCCTGGGCTGTCAGAAAGTAGAGGTGGCACCTGGCTATGTGGTGACCGTGTTGACCTGG
CCAGGCACCAACCCTACACTCTCCTCCATCTTGCTCAACTCCCACACGGATGTGGTGCCTGTCTTCAAGGAACATTGGAGTCACGACCCC
TTTGAGGCCTTCAAGGATTCTGAGGGCTACATCTATGCCAGGGGTGCCCAGGACATGAAGTGCGTCAGCATCCAGTACCTGGAAGCTGTG
AGGAGGCTGAAGGTGGAGGGCCACCGGTTCCCCAGAACCATCCACATGACCTTTGTGCCTGATGAGGAGGTTGGGGGTCACCAAGGCATG
GAGCTGTTCGTGCAGCGGCCTGAGTTCCACGCCCTGAGGGCAGGCTTTGCCCTGGATGAGGGCATAGCCAATCCCACTGATGCCTTCACT
GTCTTTTATAGTGAGCGGAGTCCCTGGTGGGTGCGGGTTACCAGCACTGGGAGGCCAGGCCATGCCTCACGCTTCATGGAGGACACAGCA
GCAGAGAAGCTGGCTTTTGAGGAGCAGCTGCAGAGCTGGTGCCAGGCAGCTGGCGAGGGGGTCACCCTAGAGTTTGCTCAGAGCAAAGGA
TATGCGATTGGCAATGCCCCGGAGTTGGCCAAGGCCCATAATAGCCATGCCAGGCCCGAGCCACGCCACCTCCCTGAGAAGCAGAATGGC
CTTAGTGCAGTGCGGACCATGGAGGCGTTCCACTTTGTCAGCTATGTGCCTATCACAGGCCGGCTCTTTGAGCTGGATGGGCTGAAGGTC
TACCCCATTGACCATGGGCCCTGGGGGGAGGACGAGGAGTGGACAGACAAGGCCCGGCGGGTCATCATGGAGCGTATCGGCCTCGCCACT
GCAGGGGAGCCCTACCACGACATCCGCTTCAACCTGATGGCAGTGGTGCCCGACCGCAGGATCAAGTATGAGGCCAGGCTGCATGTGCTG
AAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGATAAGAGTAACACAGCCAGAGCTGATTCAGACCCACAAGTCTCAAGAG
TCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCCGCTGGTGCTGGAAGCAAACAGGGCCCCTGCAGCCTCTGAGGGCAAC
CACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGCCCCATCCCACAGCCCTCCCAACAAACCCAAGCTAGTGGTGAAGCCT
CCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCATTGTCCAGCGGCTGCCGGCCTTTCTAGACAATCACAATTATGCCAAG
TCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCGCAGCCGAGTTCCAGTCCGCCCACCCCAGCAGTACTCAGATGATGAG
GATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAACTCTGCCCTTAGGTATAAGGGGAAGGGAACAGGGAAGCCAGGGGCA
TTGAGCGGTTCTGCTGATGGGCAACTGTCAGTGCTGCAGCCCAACACCATCAACGTCTTGGCTGAGAAGCTCAAAGAGTCCCAGAAGGAC
CTCTCAATTCCTCTGTCCATCAAGACTAGCAGCGGGGCTGGGAGTCCGGCTGTGGCAGTGCCCACACACTCGCAGCCCTCACCCACCCCC
AGCAATGAGAGTACAGACACGGCCTCTGAGATCGGCAGTGCTTTCAACTCGCCACTGCGCTCGCCTATCCGCTCAGCCAACCCGACGCGG
CCCTCCAGCCCTGTCACCTCCCACATCTCCAAGGTGCTTTTTGGAGAGGATGACAGCCTGCTGCGTGTTGACTGCATACGCTACAACCGT
GCTGTCCGTGATCTGGGTCCTGTCATCAGCACAGGCCTGCTGCACCTGGCTGAGGATGGGGTGCTGAGTCCCCTGGCGCTGACAGAGGGT
GGGAAGGGTTCCTCGCCCTCCATCAGACCAATCCAAGGCAGCCAGGGGTCCAGCAGCCCAGTGGAGAAGGAGGTCGTGGAAGCCACGGAC
AGCAGAGAGAAGACGGGGATGGTGAGGCCTGGCGAGCCCTTGAGTGGGGAGAAATACTCACCCAAGGAGCTGCTGGCACTGCTGAAGTGT
GTGGAGGCTGAGATTGCAAACTATGAGGCGTGCCTCAAGGAGGAGGTAGAGAAGAGGAAGAAGTTCAAGATTGATGACCAGAGAAGGACC
CACAACTACGATGAGTTCATCTGCACCTTTATCTCCATGCTGGCTCAGGAAGGCATGCTGGCCAACCTAGTGGAGCAGAACATCTCCGTG
CGGCGGCGCCAAGGGGTCAGCATCGGCCGGCTCCACAAGCAGCGGAAGCCTGACCGGCGGAAACGCTCTCGCCCCTACAAGGCCAAGCGC
CAGTGAGGACTGCTGGCCCTGACTCTGCAGCCCACTCTTGCCGTGTGGCCCTCACCAGGGTCCTTCCCTGCCCCACTTCCCCTTTTCCCA
GTATTACTGAATAGTCCCAGCTGGAGAGTCCAGGCCCTGGGAATGGGAGGAACCAGGCCACATTCCTTCCATCGTGCCCTGAGGCCTGAC
ACGGCAGATCAGCCCCATAGTGCTCAGGAGGCAGCATCTGGAGTTGGGGCACAGCGAGGTACTGCAGCTTCCTCCACAGCCGGCTGTGGA
GCAGCAGGACCTGGCCCTTCTGCCTGGGCAGCAGAATATATATTTTACCTATCAGAGACATCTATTTTTCTGGGCTCCAACCCAACATGC
CACCATGTTGACATAAGTTCCTACCTGACTATGCTTTCTCTCCTAGGAGCTGTCCTGGTGGGCCCAGGTCCTTGTATCATGCCACGGTCC
CAACTACAGGGTCCTAGCTGGGGGCCTGGGTGGGCCCTGGGCTCTGGGCCCTGCTGCTCTAGCCCCAGCCACCAGCCTGTCCCTGTTGTA
AGGAAGCCAGGTCTTCTCTCTTCATTCCTCTTAGGAGAGTGCCAAACTCAGGGACCCAGCACTGGGCTGGGTTGGGAGTAGGGTGTCCCA
GTGGGGTTGGGGTGAGCAGGCTGCTGGGATCCCATGGCCTGAGCAGAGCATGTGGGAACTGTTCAGTGGCCTGTGAACTGTCTTCCTTGT
TCTAGCCAGGCTGTTCAAGACTGCTCTCCATAGCAAGGTTCTAGGGCTCTTCGCCTTCAGTGTTGTGGCCCTAGCTATGGGCCTAAATTG
GGCTCTAGGTCTCTGTCCCTGGCGCTTGAGGCTCAGAAGAGCCTCTGTCCAGCCCCTCAGTATTACCATGTCTCCCTCTCAGGGGTAGCA
GAGACAGGGTTGCTTATAGGAAGCTGGCACCACTCAGCTCTTCCTGCTACTCCAGTTTCCTCAGCCTCTGCAAGGCACTCAGGGTGGGGG
ACAGCAGGATCAAGACAACCCGTTGGAGCCCCTGTGTTCCAGAGGACCTGATGCCAAGGGGTAATGGGCCCAGCAGTGCCTCTGGAGCCC
AGGCCCCAACACAGCCCCATGGCCTCTGCCAGATGGCTTTGAAAAAGGTGATCCAAGCAGGCCCCTTTATCTGTACATAGTGACTGAGTG
GGGGGTGCTGGCAAGTGTGGCAGCTGCCTCTGGGCTGAGCACAGCTTGACCCCTCTAGCCCCTGTAAATACTGGATCAATGAATGAATAA

>1916_1916_8_ACY1-BAP1_ACY1_chr3_52021640_ENST00000476854_BAP1_chr3_52441476_ENST00000460680_length(amino acids)=846AA_BP=242
MTSKGPEEEHPSVTLFRQYLRIRTVQPKPDYGAAVAFFEETARQLGLGCQKVEVAPGYVVTVLTWPGTNPTLSSILLNSHTDVVPVFKEH
WSHDPFEAFKDSEGYIYARGAQDMKCVSIQYLEAVRRLKVEGHRFPRTIHMTFVPDEEVGGHQGMELFVQRPEFHALRAGFALDEGIANP
TDAFTVFYSERSPWWVRVTSTGRPGHASRFMEDTAAEKLAFEEQLQSWCQAAGEGVTLEFAQSKGYAIGNAPELAKAHNSHARPEPRHLP
EKQNGLSAVRTMEAFHFVSYVPITGRLFELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRIKYEA
RLHVLKVNRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKSASNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPK
LVVKPPGSSLNGVHPNPTPIVQRLPAFLDNHNYAKSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRYKGKGT
GKPGALSGSADGQLSVLQPNTINVLAEKLKESQKDLSIPLSIKTSSGAGSPAVAVPTHSQPSPTPSNESTDTASEIGSAFNSPLRSPIRS
ANPTRPSSPVTSHISKVLFGEDDSLLRVDCIRYNRAVRDLGPVISTGLLHLAEDGVLSPLALTEGGKGSSPSIRPIQGSQGSSSPVEKEV
VEATDSREKTGMVRPGEPLSGEKYSPKELLALLKCVEAEIANYEACLKEEVEKRKKFKIDDQRRTHNYDEFICTFISMLAQEGMLANLVE

--------------------------------------------------------------
>1916_1916_9_ACY1-BAP1_ACY1_chr3_52021640_ENST00000494103_BAP1_chr3_52441476_ENST00000296288_length(transcript)=3893nt_BP=870nt
CGACATCCGGCCTCGGCCACGTGGTGGGCGGACCGGGGCGGTCCTGAGCCTGCGACCTCGCAGGCGACCTCGCTGGACCCTAAGTCCAGG
CCACAGTCAGGGAAGGGCGCTGAGAGGCGAGCGTGAGCCCAGCGACAGGAGAGTGAGCTCACCACGCGCAGCGCCATGACCAGCAAGGGT
CCCGAGGAGGAGCACCCATCGGTGACGCTCTTCCGCCAGTACCTGCGTATCCGCACTGTCCAGCCCAAGCCTGACTATGGAGCTGCTGTG
GCTTTCTTTGAGGAGACAGCCCGCCAGCTGGGCCTGGGCTGTCAGAAAGTAGAGGTGGCACCTGGCTATGTGGTGACCGTGTTGACCTGG
CCAGGCACCAACCCTACACTCTCCTCCATCTTGCTCAACTCCCACACGGATGTGGTGCCTGTCTTCAAGGAACATTGGAGTCACGACCCC
TTTGAGGCCTTCAAGGATTCTGAGGGCATAGCCAATCCCACTGATGCCTTCACTGTCTTTTATAGTGAGCGGAGTCCCTGGTGGGTGCGG
GTTACCAGCACTGGGAGGCCAGGCCATGCCTCACGCTTCATGGAGGACACAGCAGCAGAGAAGCTGCACAAGGTTGTAAACTCCATCCTG
GCATTCCGGGAGAAGGAATGGCAGAGGCTGCAGTCAAACCCCCACCTGAAAGAGGGGTCCGTGACCTCCGTGAACCTGACTAAGCTAGAG
GGTGGCGTGGCCTATAACGTGATACCTGCCACCATGAGCGCCAGCTTTGACTTCCGTGTGGCACCGGATGTGGACTTCAAGGCTTTTGAG
GAGCAGCTGCAGAGCTGGTGCCAGGCAGCTGGCGAGGGGGTCACCCTAGAGTTTGCTCAGAGCAAAGGATATGCGATTGGCAATGCCCCG
GAGTTGGCCAAGGCCCATAATAGCCATGCCAGGCCCGAGCCACGCCACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATG
GAGGCGTTCCACTTTGTCAGCTATGTGCCTATCACAGGCCGGCTCTTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCC
TGGGGGGAGGACGAGGAGTGGACAGACAAGGCCCGGCGGGTCATCATGGAGCGTATCGGCCTCGCCACTGCAGGGATCAAGTATGAGGCC
AGGCTGCATGTGCTGAAGGTGAACCGTCAGACAGTACTAGAGGCTCTGCAGCAGCTGATAAGAGTAACACAGCCAGAGCTGATTCAGACC
CACAAGTCTCAAGAGTCACAGCTGCCTGAGGAGTCCAAGTCAGCCAGCAACAAGTCCCCGCTGGTGCTGGAAGCAAACAGGGCCCCTGCA
GCCTCTGAGGGCAACCACACAGATGGTGCAGAGGAGGCGGCTGGTTCATGCGCACAAGCCCCATCCCACAGCCCTCCCAACAAACCCAAG
CTAGTGGTGAAGCCTCCAGGCAGCAGCCTCAATGGGGTTCACCCCAACCCCACTCCCATTGTCCAGCGGCTGCCGGCCTTTCTAGACAAT
CACAATTATGCCAAGTCCCCCATGCAGGAGGAAGAAGACCTGGCGGCAGGTGTGGGCCGCAGCCGAGTTCCAGTCCGCCCACCCCAGCAG
TACTCAGATGATGAGGATGACTATGAGGATGACGAGGAGGATGACGTGCAGAACACCAACTCTGCCCTTAGGTATAAGGGGAAGGGAACA
GGGAAGCCAGGGGCATTGAGCGGTTCTGCTGATGGGCAACTGTCAGTGCTGCAGCCCAACACCATCAACGTCTTGGCTGAGAAGCTCAAA
GAGTCCCAGAAGGACCTCTCAATTCCTCTGTCCATCAAGACTAGCAGCGGGGCTGGGAGTCCGGCTGTGGCAGTGCCCACACACTCGCAG
CCCTCACCCACCCCCAGCAATGAGAGTACAGACACGGCCTCTGAGATCGGCAGTGCTTTCAACTCGCCACTGCGCTCGCCTATCCGCTCA
GCCAACCCGACGCGGCCCTCCAGCCCTGTCACCTCCCACATCTCCAAGGTGCTTTTTGGAGAGGATGACAGCCTGCTGCGTGTTGACTGC
ATACGCTACAACCGTGCTGTCCGTGATCTGGGTCCTGTCATCAGCACAGGCCTGCTGCACCTGGCTGAGGATGGGGTGCTGAGTCCCCTG
GCGCTGACAGAGGGTGGGAAGGGTTCCTCGCCCTCCATCAGACCAATCCAAGGCAGCCAGGGGTCCAGCAGCCCAGTGGAGAAGGAGGTC
GTGGAAGCCACGGACAGCAGAGAGAAGACGGGGATGGTGAGGCCTGGCGAGCCCTTGAGTGGGGAGAAATACTCACCCAAGGAGCTGCTG
GCACTGCTGAAGTGTGTGGAGGCTGAGATTGCAAACTATGAGGCGTGCCTCAAGGAGGAGGTAGAGAAGAGGAAGAAGTTCAAGATTGAT
GACCAGAGAAGGACCCACAACTACGATGAGTTCATCTGCACCTTTATCTCCATGCTGGCTCAGGAAGGCATGCTGGCCAACCTAGTGGAG
CAGAACATCTCCGTGCGGCGGCGCCAAGGGGTCAGCATCGGCCGGCTCCACAAGCAGCGGAAGCCTGACCGGCGGAAACGCTCTCGCCCC
TACAAGGCCAAGCGCCAGTGAGGACTGCTGGCCCTGACTCTGCAGCCCACTCTTGCCGTGTGGCCCTCACCAGGGTCCTTCCCTGCCCCA
CTTCCCCTTTTCCCAGTATTACTGAATAGTCCCAGCTGGAGAGTCCAGGCCCTGGGAATGGGAGGAACCAGGCCACATTCCTTCCATCGT
GCCCTGAGGCCTGACACGGCAGATCAGCCCCATAGTGCTCAGGAGGCAGCATCTGGAGTTGGGGCACAGCGAGGTACTGCAGCTTCCTCC
ACAGCCGGCTGTGGAGCAGCAGGACCTGGCCCTTCTGCCTGGGCAGCAGAATATATATTTTACCTATCAGAGACATCTATTTTTCTGGGC
TCCAACCCAACATGCCACCATGTTGACATAAGTTCCTACCTGACTATGCTTTCTCTCCTAGGAGCTGTCCTGGTGGGCCCAGGTCCTTGT
ATCATGCCACGGTCCCAACTACAGGGTCCTAGCTGGGGGCCTGGGTGGGCCCTGGGCTCTGGGCCCTGCTGCTCTAGCCCCAGCCACCAG
CCTGTCCCTGTTGTAAGGAAGCCAGGTCTTCTCTCTTCATTCCTCTTAGGAGAGTGCCAAACTCAGGGACCCAGCACTGGGCTGGGTTGG
GAGTAGGGTGTCCCAGTGGGGTTGGGGTGAGCAGGCTGCTGGGATCCCATGGCCTGAGCAGAGCATGTGGGAACTGTTCAGTGGCCTGTG
AACTGTCTTCCTTGTTCTAGCCAGGCTGTTCAAGACTGCTCTCCATAGCAAGGTTCTAGGGCTCTTCGCCTTCAGTGTTGTGGCCCTAGC
TATGGGCCTAAATTGGGCTCTAGGTCTCTGTCCCTGGCGCTTGAGGCTCAGAAGAGCCTCTGTCCAGCCCCTCAGTATTACCATGTCTCC
CTCTCAGGGGTAGCAGAGACAGGGTTGCTTATAGGAAGCTGGCACCACTCAGCTCTTCCTGCTACTCCAGTTTCCTCAGCCTCTGCAAGG
CACTCAGGGTGGGGGACAGCAGGATCAAGACAACCCGTTGGAGCCCCTGTGTTCCAGAGGACCTGATGCCAAGGGGTAATGGGCCCAGCA
GTGCCTCTGGAGCCCAGGCCCCAACACAGCCCCATGGCCTCTGCCAGATGGCTTTGAAAAAGGTGATCCAAGCAGGCCCCTTTATCTGTA
CATAGTGACTGAGTGGGGGGTGCTGGCAAGTGTGGCAGCTGCCTCTGGGCTGAGCACAGCTTGACCCCTCTAGCCCCTGTAAATACTGGA

>1916_1916_9_ACY1-BAP1_ACY1_chr3_52021640_ENST00000494103_BAP1_chr3_52441476_ENST00000296288_length(amino acids)=821AA_BP=235
MTSKGPEEEHPSVTLFRQYLRIRTVQPKPDYGAAVAFFEETARQLGLGCQKVEVAPGYVVTVLTWPGTNPTLSSILLNSHTDVVPVFKEH
WSHDPFEAFKDSEGIANPTDAFTVFYSERSPWWVRVTSTGRPGHASRFMEDTAAEKLHKVVNSILAFREKEWQRLQSNPHLKEGSVTSVN
LTKLEGGVAYNVIPATMSASFDFRVAPDVDFKAFEEQLQSWCQAAGEGVTLEFAQSKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLS
AVRTMEAFHFVSYVPITGRLFELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGIKYEARLHVLKVNRQTVLEALQQLIRVTQP
ELIQTHKSQESQLPEESKSASNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPGSSLNGVHPNPTPIVQRLP
AFLDNHNYAKSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRYKGKGTGKPGALSGSADGQLSVLQPNTINVL
AEKLKESQKDLSIPLSIKTSSGAGSPAVAVPTHSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPSSPVTSHISKVLFGEDDSL
LRVDCIRYNRAVRDLGPVISTGLLHLAEDGVLSPLALTEGGKGSSPSIRPIQGSQGSSSPVEKEVVEATDSREKTGMVRPGEPLSGEKYS
PKELLALLKCVEAEIANYEACLKEEVEKRKKFKIDDQRRTHNYDEFICTFISMLAQEGMLANLVEQNISVRRRQGVSIGRLHKQRKPDRR

--------------------------------------------------------------
>1916_1916_10_ACY1-BAP1_ACY1_chr3_52021640_ENST00000494103_BAP1_chr3_52441476_ENST00000460680_length(transcript)=3960nt_BP=870nt
CGACATCCGGCCTCGGCCACGTGGTGGGCGGACCGGGGCGGTCCTGAGCCTGCGACCTCGCAGGCGACCTCGCTGGACCCTAAGTCCAGG
CCACAGTCAGGGAAGGGCGCTGAGAGGCGAGCGTGAGCCCAGCGACAGGAGAGTGAGCTCACCACGCGCAGCGCCATGACCAGCAAGGGT
CCCGAGGAGGAGCACCCATCGGTGACGCTCTTCCGCCAGTACCTGCGTATCCGCACTGTCCAGCCCAAGCCTGACTATGGAGCTGCTGTG
GCTTTCTTTGAGGAGACAGCCCGCCAGCTGGGCCTGGGCTGTCAGAAAGTAGAGGTGGCACCTGGCTATGTGGTGACCGTGTTGACCTGG
CCAGGCACCAACCCTACACTCTCCTCCATCTTGCTCAACTCCCACACGGATGTGGTGCCTGTCTTCAAGGAACATTGGAGTCACGACCCC
TTTGAGGCCTTCAAGGATTCTGAGGGCATAGCCAATCCCACTGATGCCTTCACTGTCTTTTATAGTGAGCGGAGTCCCTGGTGGGTGCGG
GTTACCAGCACTGGGAGGCCAGGCCATGCCTCACGCTTCATGGAGGACACAGCAGCAGAGAAGCTGCACAAGGTTGTAAACTCCATCCTG
GCATTCCGGGAGAAGGAATGGCAGAGGCTGCAGTCAAACCCCCACCTGAAAGAGGGGTCCGTGACCTCCGTGAACCTGACTAAGCTAGAG
GGTGGCGTGGCCTATAACGTGATACCTGCCACCATGAGCGCCAGCTTTGACTTCCGTGTGGCACCGGATGTGGACTTCAAGGCTTTTGAG
GAGCAGCTGCAGAGCTGGTGCCAGGCAGCTGGCGAGGGGGTCACCCTAGAGTTTGCTCAGAGCAAAGGATATGCGATTGGCAATGCCCCG
GAGTTGGCCAAGGCCCATAATAGCCATGCCAGGCCCGAGCCACGCCACCTCCCTGAGAAGCAGAATGGCCTTAGTGCAGTGCGGACCATG
GAGGCGTTCCACTTTGTCAGCTATGTGCCTATCACAGGCCGGCTCTTTGAGCTGGATGGGCTGAAGGTCTACCCCATTGACCATGGGCCC
TGGGGGGAGGACGAGGAGTGGACAGACAAGGCCCGGCGGGTCATCATGGAGCGTATCGGCCTCGCCACTGCAGGGGAGCCCTACCACGAC
ATCCGCTTCAACCTGATGGCAGTGGTGCCCGACCGCAGGATCAAGTATGAGGCCAGGCTGCATGTGCTGAAGGTGAACCGTCAGACAGTA
CTAGAGGCTCTGCAGCAGCTGATAAGAGTAACACAGCCAGAGCTGATTCAGACCCACAAGTCTCAAGAGTCACAGCTGCCTGAGGAGTCC
AAGTCAGCCAGCAACAAGTCCCCGCTGGTGCTGGAAGCAAACAGGGCCCCTGCAGCCTCTGAGGGCAACCACACAGATGGTGCAGAGGAG
GCGGCTGGTTCATGCGCACAAGCCCCATCCCACAGCCCTCCCAACAAACCCAAGCTAGTGGTGAAGCCTCCAGGCAGCAGCCTCAATGGG
GTTCACCCCAACCCCACTCCCATTGTCCAGCGGCTGCCGGCCTTTCTAGACAATCACAATTATGCCAAGTCCCCCATGCAGGAGGAAGAA
GACCTGGCGGCAGGTGTGGGCCGCAGCCGAGTTCCAGTCCGCCCACCCCAGCAGTACTCAGATGATGAGGATGACTATGAGGATGACGAG
GAGGATGACGTGCAGAACACCAACTCTGCCCTTAGGTATAAGGGGAAGGGAACAGGGAAGCCAGGGGCATTGAGCGGTTCTGCTGATGGG
CAACTGTCAGTGCTGCAGCCCAACACCATCAACGTCTTGGCTGAGAAGCTCAAAGAGTCCCAGAAGGACCTCTCAATTCCTCTGTCCATC
AAGACTAGCAGCGGGGCTGGGAGTCCGGCTGTGGCAGTGCCCACACACTCGCAGCCCTCACCCACCCCCAGCAATGAGAGTACAGACACG
GCCTCTGAGATCGGCAGTGCTTTCAACTCGCCACTGCGCTCGCCTATCCGCTCAGCCAACCCGACGCGGCCCTCCAGCCCTGTCACCTCC
CACATCTCCAAGGTGCTTTTTGGAGAGGATGACAGCCTGCTGCGTGTTGACTGCATACGCTACAACCGTGCTGTCCGTGATCTGGGTCCT
GTCATCAGCACAGGCCTGCTGCACCTGGCTGAGGATGGGGTGCTGAGTCCCCTGGCGCTGACAGAGGGTGGGAAGGGTTCCTCGCCCTCC
ATCAGACCAATCCAAGGCAGCCAGGGGTCCAGCAGCCCAGTGGAGAAGGAGGTCGTGGAAGCCACGGACAGCAGAGAGAAGACGGGGATG
GTGAGGCCTGGCGAGCCCTTGAGTGGGGAGAAATACTCACCCAAGGAGCTGCTGGCACTGCTGAAGTGTGTGGAGGCTGAGATTGCAAAC
TATGAGGCGTGCCTCAAGGAGGAGGTAGAGAAGAGGAAGAAGTTCAAGATTGATGACCAGAGAAGGACCCACAACTACGATGAGTTCATC
TGCACCTTTATCTCCATGCTGGCTCAGGAAGGCATGCTGGCCAACCTAGTGGAGCAGAACATCTCCGTGCGGCGGCGCCAAGGGGTCAGC
ATCGGCCGGCTCCACAAGCAGCGGAAGCCTGACCGGCGGAAACGCTCTCGCCCCTACAAGGCCAAGCGCCAGTGAGGACTGCTGGCCCTG
ACTCTGCAGCCCACTCTTGCCGTGTGGCCCTCACCAGGGTCCTTCCCTGCCCCACTTCCCCTTTTCCCAGTATTACTGAATAGTCCCAGC
TGGAGAGTCCAGGCCCTGGGAATGGGAGGAACCAGGCCACATTCCTTCCATCGTGCCCTGAGGCCTGACACGGCAGATCAGCCCCATAGT
GCTCAGGAGGCAGCATCTGGAGTTGGGGCACAGCGAGGTACTGCAGCTTCCTCCACAGCCGGCTGTGGAGCAGCAGGACCTGGCCCTTCT
GCCTGGGCAGCAGAATATATATTTTACCTATCAGAGACATCTATTTTTCTGGGCTCCAACCCAACATGCCACCATGTTGACATAAGTTCC
TACCTGACTATGCTTTCTCTCCTAGGAGCTGTCCTGGTGGGCCCAGGTCCTTGTATCATGCCACGGTCCCAACTACAGGGTCCTAGCTGG
GGGCCTGGGTGGGCCCTGGGCTCTGGGCCCTGCTGCTCTAGCCCCAGCCACCAGCCTGTCCCTGTTGTAAGGAAGCCAGGTCTTCTCTCT
TCATTCCTCTTAGGAGAGTGCCAAACTCAGGGACCCAGCACTGGGCTGGGTTGGGAGTAGGGTGTCCCAGTGGGGTTGGGGTGAGCAGGC
TGCTGGGATCCCATGGCCTGAGCAGAGCATGTGGGAACTGTTCAGTGGCCTGTGAACTGTCTTCCTTGTTCTAGCCAGGCTGTTCAAGAC
TGCTCTCCATAGCAAGGTTCTAGGGCTCTTCGCCTTCAGTGTTGTGGCCCTAGCTATGGGCCTAAATTGGGCTCTAGGTCTCTGTCCCTG
GCGCTTGAGGCTCAGAAGAGCCTCTGTCCAGCCCCTCAGTATTACCATGTCTCCCTCTCAGGGGTAGCAGAGACAGGGTTGCTTATAGGA
AGCTGGCACCACTCAGCTCTTCCTGCTACTCCAGTTTCCTCAGCCTCTGCAAGGCACTCAGGGTGGGGGACAGCAGGATCAAGACAACCC
GTTGGAGCCCCTGTGTTCCAGAGGACCTGATGCCAAGGGGTAATGGGCCCAGCAGTGCCTCTGGAGCCCAGGCCCCAACACAGCCCCATG
GCCTCTGCCAGATGGCTTTGAAAAAGGTGATCCAAGCAGGCCCCTTTATCTGTACATAGTGACTGAGTGGGGGGTGCTGGCAAGTGTGGC
AGCTGCCTCTGGGCTGAGCACAGCTTGACCCCTCTAGCCCCTGTAAATACTGGATCAATGAATGAATAAAACTCTCCTAAGAATCTCCTG

>1916_1916_10_ACY1-BAP1_ACY1_chr3_52021640_ENST00000494103_BAP1_chr3_52441476_ENST00000460680_length(amino acids)=839AA_BP=235
MTSKGPEEEHPSVTLFRQYLRIRTVQPKPDYGAAVAFFEETARQLGLGCQKVEVAPGYVVTVLTWPGTNPTLSSILLNSHTDVVPVFKEH
WSHDPFEAFKDSEGIANPTDAFTVFYSERSPWWVRVTSTGRPGHASRFMEDTAAEKLHKVVNSILAFREKEWQRLQSNPHLKEGSVTSVN
LTKLEGGVAYNVIPATMSASFDFRVAPDVDFKAFEEQLQSWCQAAGEGVTLEFAQSKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGLS
AVRTMEAFHFVSYVPITGRLFELDGLKVYPIDHGPWGEDEEWTDKARRVIMERIGLATAGEPYHDIRFNLMAVVPDRRIKYEARLHVLKV
NRQTVLEALQQLIRVTQPELIQTHKSQESQLPEESKSASNKSPLVLEANRAPAASEGNHTDGAEEAAGSCAQAPSHSPPNKPKLVVKPPG
SSLNGVHPNPTPIVQRLPAFLDNHNYAKSPMQEEEDLAAGVGRSRVPVRPPQQYSDDEDDYEDDEEDDVQNTNSALRYKGKGTGKPGALS
GSADGQLSVLQPNTINVLAEKLKESQKDLSIPLSIKTSSGAGSPAVAVPTHSQPSPTPSNESTDTASEIGSAFNSPLRSPIRSANPTRPS
SPVTSHISKVLFGEDDSLLRVDCIRYNRAVRDLGPVISTGLLHLAEDGVLSPLALTEGGKGSSPSIRPIQGSQGSSSPVEKEVVEATDSR
EKTGMVRPGEPLSGEKYSPKELLALLKCVEAEIANYEACLKEEVEKRKKFKIDDQRRTHNYDEFICTFISMLAQEGMLANLVEQNISVRR

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for ACY1-BAP1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneBAP1chr3:52021640chr3:52441476ENST00000460680417596_721125.0730.0BRCA1


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for ACY1-BAP1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
HgeneACY1Q03154DB06151AcetylcysteineLigandSmall moleculeApproved|Investigational
HgeneACY1Q03154DB09130CopperSmall moleculeApproved|Investigational
HgeneACY1Q03154DB00128Aspartic acidSmall moleculeApproved|Nutraceutical

Top

Related Diseases for ACY1-BAP1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneACY1C1835922Aminoacylase 1 deficiency4CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
HgeneACY1C0007134Renal Cell Carcinoma1CTD_human
HgeneACY1C0032927Precancerous Conditions1CTD_human
HgeneACY1C0279702Conventional (Clear Cell) Renal Cell Carcinoma1CTD_human
HgeneACY1C0282313Condition, Preneoplastic1CTD_human
HgeneACY1C1266042Chromophobe Renal Cell Carcinoma1CTD_human
HgeneACY1C1266043Sarcomatoid Renal Cell Carcinoma1CTD_human
HgeneACY1C1266044Collecting Duct Carcinoma of the Kidney1CTD_human
HgeneACY1C1306837Papillary Renal Cell Carcinoma1CTD_human
HgeneACY1C3714756Intellectual Disability1GENOMICS_ENGLAND
TgeneC3280492TUMOR PREDISPOSITION SYNDROME7CLINGEN;CTD_human;GENOMICS_ENGLAND;ORPHANET
TgeneC0220633Uveal melanoma5CGI;CTD_human;GENOMICS_ENGLAND;ORPHANET
TgeneC0345967Malignant mesothelioma5CTD_human
TgeneC0007134Renal Cell Carcinoma4CTD_human
TgeneC0025500Mesothelioma4CGI;CTD_human
TgeneC0279702Conventional (Clear Cell) Renal Cell Carcinoma4CGI;CTD_human
TgeneC1266042Chromophobe Renal Cell Carcinoma4CTD_human
TgeneC1266043Sarcomatoid Renal Cell Carcinoma4CTD_human
TgeneC1266044Collecting Duct Carcinoma of the Kidney4CTD_human
TgeneC1306837Papillary Renal Cell Carcinoma4CTD_human
TgeneC0006142Malignant neoplasm of breast2CGI;CTD_human
TgeneC0024623Malignant neoplasm of stomach2CTD_human
TgeneC0038356Stomach Neoplasms2CTD_human
TgeneC0151779Cutaneous Melanoma2CGI;CTD_human;GENOMICS_ENGLAND
TgeneC0206698Cholangiocarcinoma2CTD_human
TgeneC0345905Intrahepatic Cholangiocarcinoma2CTD_human
TgeneC0346373Malignant melanoma of iris2ORPHANET
TgeneC0346388Malignant melanoma of choroid2ORPHANET
TgeneC0678222Breast Carcinoma2CGI;CTD_human
TgeneC1257931Mammary Neoplasms, Human2CTD_human
TgeneC1458155Mammary Neoplasms2CTD_human
TgeneC1708349Hereditary Diffuse Gastric Cancer2CTD_human
TgeneC3805278Extrahepatic Cholangiocarcinoma2CTD_human
TgeneC4704874Mammary Carcinoma, Human2CTD_human
TgeneC0005684Malignant neoplasm of urinary bladder1CTD_human
TgeneC0005695Bladder Neoplasm1CTD_human
TgeneC0005967Bone neoplasms1CTD_human
TgeneC0007102Malignant tumor of colon1CTD_human
TgeneC0009375Colonic Neoplasms1CTD_human
TgeneC0018671Head and Neck Neoplasms1CTD_human
TgeneC0018675Head Neoplasms1CTD_human
TgeneC0022665Kidney Neoplasm1CGI;CTD_human
TgeneC0023418leukemia1CTD_human
TgeneC0023798Lipoma1CTD_human
TgeneC0023903Liver neoplasms1CTD_human
TgeneC0024121Lung Neoplasms1CTD_human
TgeneC0025286Meningioma1CTD_human;GENOMICS_ENGLAND
TgeneC0027533Neck Neoplasms1CTD_human
TgeneC0030297Pancreatic Neoplasm1CTD_human
TgeneC0030421Paraganglioma1CTD_human
TgeneC0033578Prostatic Neoplasms1CTD_human
TgeneC0039590Testicular Neoplasms1CTD_human
TgeneC0040100Thymoma1CTD_human
TgeneC0042138Uterine Neoplasms1CTD_human
TgeneC0085136Central Nervous System Neoplasms1CTD_human
TgeneC0152013Adenocarcinoma of lung (disorder)1CTD_human
TgeneC0153567Uterine Cancer1CTD_human
TgeneC0153594Malignant neoplasm of testis1CTD_human
TgeneC0205822Hibernoma1CTD_human
TgeneC0205823Pleomorphic Lipoma1CTD_human
TgeneC0205834Meningiomas, Multiple1CTD_human
TgeneC0205969Thymic Carcinoma1CTD_human
TgeneC0206686Adrenocortical carcinoma1CTD_human
TgeneC0206694Mucoepidermoid Carcinoma1CTD_human
TgeneC0206739Epithelioid and spindle cell nevus1CTD_human
TgeneC0206754Neuroendocrine Tumors1CTD_human
TgeneC0206769Nevi and Melanomas1CTD_human
TgeneC0242379Malignant neoplasm of lung1CTD_human;UNIPROT
TgeneC0259785Malignant Meningioma1CTD_human
TgeneC0278996Malignant Head and Neck Neoplasm1CTD_human
TgeneC0279530Malignant Bone Neoplasm1CTD_human
TgeneC0281784Benign Meningioma1CTD_human
TgeneC0334605Meningothelial meningioma1CTD_human
TgeneC0334606Fibrous Meningioma1CTD_human
TgeneC0334607Psammomatous Meningioma1CTD_human
TgeneC0334608Angiomatous Meningioma1CTD_human
TgeneC0334609Hemangioblastic Meningioma1CTD_human
TgeneC0334610Hemangiopericytic Meningioma1CTD_human
TgeneC0334611Transitional Meningioma1CTD_human
TgeneC0345904Malignant neoplasm of liver1CTD_human
TgeneC0346647Malignant neoplasm of pancreas1CTD_human
TgeneC0347515Spinal Meningioma1CTD_human
TgeneC0349604Intracranial Meningioma1CTD_human
TgeneC0376358Malignant neoplasm of prostate1CTD_human
TgeneC0431121Clear Cell Meningioma1CTD_human
TgeneC0457190Xanthomatous Meningioma1CTD_human
TgeneC0740457Malignant neoplasm of kidney1CGI;CTD_human
TgeneC0746787Cancer of Neck1CTD_human
TgeneC0751177Cancer of Head1CTD_human
TgeneC0751303Cerebral Convexity Meningioma1CTD_human
TgeneC0751304Parasagittal Meningioma1CTD_human
TgeneC0751620Central Nervous System Neoplasms, Primary1CTD_human
TgeneC0887900Upper Aerodigestive Tract Neoplasms1CTD_human
TgeneC0919267ovarian neoplasm1CTD_human
TgeneC1140680Malignant neoplasm of ovary1CTD_human
TgeneC1334261Intraorbital Meningioma1CTD_human
TgeneC1334271Intraventricular Meningioma1CTD_human
TgeneC1335107Olfactory Groove Meningioma1CTD_human
TgeneC1368275Pigmented Basal Cell Carcinoma1CTD_human
TgeneC1384406Secretory meningioma1CTD_human
TgeneC1384408Microcystic meningioma1CTD_human
TgeneC1527197Angioblastic Meningioma1CTD_human
TgeneC1565950Posterior Fossa Meningioma1CTD_human
TgeneC1565951Sphenoid Wing Meningioma1CTD_human
TgeneC1708353Hereditary Paraganglioma-Pheochromocytoma Syndrome1CLINGEN
TgeneC1720811Tumor of Rete Testis1CTD_human
TgeneC2314896Familial Atypical Mole Melanoma Syndrome1ORPHANET
TgeneC2931822Nasopharyngeal carcinoma1CTD_human
TgeneC3163622Papillary Meningioma1CTD_human
TgeneC3489413Lipomatosis, Multiple1CTD_human
TgeneC4721806Carcinoma, Basal Cell1CTD_human