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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Diseases

Fusion gene:ABCG1-BACE2 (FusionGDB2 ID:HG9619TG25825)

Fusion Gene Summary for ABCG1-BACE2

check button Fusion gene summary
Fusion gene informationFusion gene name: ABCG1-BACE2
Fusion gene ID: hg9619tg25825
HgeneTgene
Gene symbol

ABCG1

BACE2

Gene ID

9619

25825

Gene nameATP binding cassette subfamily G member 1beta-secretase 2
SynonymsABC8|WHITE1AEPLC|ALP56|ASP1|ASP21|BAE2|CDA13|CEAP1|DRAP
Cytomap('ABCG1')('BACE2')

21q22.3

21q22.2-q22.3

Type of geneprotein-codingprotein-coding
DescriptionATP-binding cassette sub-family G member 1ABC transporter 8ATP-binding cassette transporter 8ATP-binding cassette transporter member 1 of subfamily GATP-binding cassette, sub-family G (WHITE), member 1homolog of Drosophila whitewhite protein homologbeta-secretase 256 kDa aspartic-like proteaseDown syndrome region aspartic proteaseSLCO3A1/BACE2 fusionaspartyl protease 1beta-site APP-cleaving enzyme 2beta-site amyloid beta A4 precursor protein-cleaving enzyme 2memapsin-1membrane-associated asp
Modification date2020032920200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000462050, ENST00000340588, 
ENST00000343687, ENST00000347800, 
ENST00000361802, ENST00000398437, 
ENST00000398449, ENST00000398457, 
Fusion gene scores* DoF score8 X 7 X 4=22414 X 9 X 8=1008
# samples 714
** MAII scorelog2(7/224*10)=-1.67807190511264
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(14/1008*10)=-2.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ABCG1 [Title/Abstract] AND BACE2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointABCG1(43708422)-BACE2(42598193), # samples:3
Anticipated loss of major functional domain due to fusion event.ABCG1-BACE2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ABCG1-BACE2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
ABCG1-BACE2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
ABCG1-BACE2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneABCG1

GO:0008203

cholesterol metabolic process

15994327

HgeneABCG1

GO:0033344

cholesterol efflux

15994327

HgeneABCG1

GO:0033993

response to lipid

16556852

HgeneABCG1

GO:0034436

glycoprotein transport

17293612

HgeneABCG1

GO:0042632

cholesterol homeostasis

15994327

HgeneABCG1

GO:0042987

amyloid precursor protein catabolic process

17293612

HgeneABCG1

GO:0050714

positive regulation of protein secretion

17293612

HgeneABCG1

GO:1902004

positive regulation of amyloid-beta formation

17293612

TgeneBACE2

GO:0006509

membrane protein ectodomain proteolysis

10591213


check buttonFusion gene breakpoints across ABCG1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure
check buttonFusion gene breakpoints across BACE2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4UCECTCGA-B5-A3FB-01AABCG1chr21

43708422

-BACE2chr21

42598193

+
ChimerDB4UCECTCGA-B5-A3FB-01AABCG1chr21

43708422

+BACE2chr21

42598193

+


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Fusion Gene ORF analysis for ABCG1-BACE2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000462050ENST00000328735ABCG1chr21

43708422

+BACE2chr21

42598193

+
3UTR-3CDSENST00000462050ENST00000330333ABCG1chr21

43708422

+BACE2chr21

42598193

+
3UTR-3CDSENST00000462050ENST00000347667ABCG1chr21

43708422

+BACE2chr21

42598193

+
3UTR-intronENST00000462050ENST00000466122ABCG1chr21

43708422

+BACE2chr21

42598193

+
5CDS-intronENST00000340588ENST00000466122ABCG1chr21

43708422

+BACE2chr21

42598193

+
5CDS-intronENST00000343687ENST00000466122ABCG1chr21

43708422

+BACE2chr21

42598193

+
5CDS-intronENST00000347800ENST00000466122ABCG1chr21

43708422

+BACE2chr21

42598193

+
5CDS-intronENST00000361802ENST00000466122ABCG1chr21

43708422

+BACE2chr21

42598193

+
5CDS-intronENST00000398437ENST00000466122ABCG1chr21

43708422

+BACE2chr21

42598193

+
5CDS-intronENST00000398449ENST00000466122ABCG1chr21

43708422

+BACE2chr21

42598193

+
5CDS-intronENST00000398457ENST00000466122ABCG1chr21

43708422

+BACE2chr21

42598193

+
In-frameENST00000340588ENST00000328735ABCG1chr21

43708422

+BACE2chr21

42598193

+
In-frameENST00000340588ENST00000330333ABCG1chr21

43708422

+BACE2chr21

42598193

+
In-frameENST00000340588ENST00000347667ABCG1chr21

43708422

+BACE2chr21

42598193

+
In-frameENST00000343687ENST00000328735ABCG1chr21

43708422

+BACE2chr21

42598193

+
In-frameENST00000343687ENST00000330333ABCG1chr21

43708422

+BACE2chr21

42598193

+
In-frameENST00000343687ENST00000347667ABCG1chr21

43708422

+BACE2chr21

42598193

+
In-frameENST00000347800ENST00000328735ABCG1chr21

43708422

+BACE2chr21

42598193

+
In-frameENST00000347800ENST00000330333ABCG1chr21

43708422

+BACE2chr21

42598193

+
In-frameENST00000347800ENST00000347667ABCG1chr21

43708422

+BACE2chr21

42598193

+
In-frameENST00000361802ENST00000328735ABCG1chr21

43708422

+BACE2chr21

42598193

+
In-frameENST00000361802ENST00000330333ABCG1chr21

43708422

+BACE2chr21

42598193

+
In-frameENST00000361802ENST00000347667ABCG1chr21

43708422

+BACE2chr21

42598193

+
In-frameENST00000398437ENST00000328735ABCG1chr21

43708422

+BACE2chr21

42598193

+
In-frameENST00000398437ENST00000330333ABCG1chr21

43708422

+BACE2chr21

42598193

+
In-frameENST00000398437ENST00000347667ABCG1chr21

43708422

+BACE2chr21

42598193

+
In-frameENST00000398449ENST00000328735ABCG1chr21

43708422

+BACE2chr21

42598193

+
In-frameENST00000398449ENST00000330333ABCG1chr21

43708422

+BACE2chr21

42598193

+
In-frameENST00000398449ENST00000347667ABCG1chr21

43708422

+BACE2chr21

42598193

+
In-frameENST00000398457ENST00000328735ABCG1chr21

43708422

+BACE2chr21

42598193

+
In-frameENST00000398457ENST00000330333ABCG1chr21

43708422

+BACE2chr21

42598193

+
In-frameENST00000398457ENST00000347667ABCG1chr21

43708422

+BACE2chr21

42598193

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000398457ABCG1chr2143708422+ENST00000328735BACE2chr2142598193+353914902392368709
ENST00000398457ABCG1chr2143708422+ENST00000330333BACE2chr2142598193+370814902392734831
ENST00000398457ABCG1chr2143708422+ENST00000347667BACE2chr2142598193+947914902392584781
ENST00000347800ABCG1chr2143708422+ENST00000328735BACE2chr2142598193+33431294432172709
ENST00000347800ABCG1chr2143708422+ENST00000330333BACE2chr2142598193+35121294432538831
ENST00000347800ABCG1chr2143708422+ENST00000347667BACE2chr2142598193+92831294432388781
ENST00000398449ABCG1chr2143708422+ENST00000328735BACE2chr2142598193+341813691452247700
ENST00000398449ABCG1chr2143708422+ENST00000330333BACE2chr2142598193+358713691452613822
ENST00000398449ABCG1chr2143708422+ENST00000347667BACE2chr2142598193+935813691452463772
ENST00000361802ABCG1chr2143708422+ENST00000328735BACE2chr2142598193+345414051452283712
ENST00000361802ABCG1chr2143708422+ENST00000330333BACE2chr2142598193+362314051452649834
ENST00000361802ABCG1chr2143708422+ENST00000347667BACE2chr2142598193+939414051452499784
ENST00000343687ABCG1chr2143708422+ENST00000328735BACE2chr2142598193+345714081512286711
ENST00000343687ABCG1chr2143708422+ENST00000330333BACE2chr2142598193+362614081512652833
ENST00000343687ABCG1chr2143708422+ENST00000347667BACE2chr2142598193+939714081512502783
ENST00000398437ABCG1chr2143708422+ENST00000328735BACE2chr2142598193+389518461482724858
ENST00000398437ABCG1chr2143708422+ENST00000330333BACE2chr2142598193+406418461483090980
ENST00000398437ABCG1chr2143708422+ENST00000347667BACE2chr2142598193+983518461482940930
ENST00000340588ABCG1chr2143708422+ENST00000328735BACE2chr2142598193+3633158402462820
ENST00000340588ABCG1chr2143708422+ENST00000330333BACE2chr2142598193+3802158402828942
ENST00000340588ABCG1chr2143708422+ENST00000347667BACE2chr2142598193+9573158402678892

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000398457ENST00000328735ABCG1chr2143708422+BACE2chr2142598193+0.0019134650.9980866
ENST00000398457ENST00000330333ABCG1chr2143708422+BACE2chr2142598193+0.0009029340.9990971
ENST00000398457ENST00000347667ABCG1chr2143708422+BACE2chr2142598193+0.000300730.99969935
ENST00000347800ENST00000328735ABCG1chr2143708422+BACE2chr2142598193+0.0052222510.9947778
ENST00000347800ENST00000330333ABCG1chr2143708422+BACE2chr2142598193+0.0025193370.9974807
ENST00000347800ENST00000347667ABCG1chr2143708422+BACE2chr2142598193+0.0009878690.9990121
ENST00000398449ENST00000328735ABCG1chr2143708422+BACE2chr2142598193+0.0024370010.997563
ENST00000398449ENST00000330333ABCG1chr2143708422+BACE2chr2142598193+0.0013876490.9986123
ENST00000398449ENST00000347667ABCG1chr2143708422+BACE2chr2142598193+0.0003276580.9996724
ENST00000361802ENST00000328735ABCG1chr2143708422+BACE2chr2142598193+0.0022233080.9977767
ENST00000361802ENST00000330333ABCG1chr2143708422+BACE2chr2142598193+0.0012259930.998774
ENST00000361802ENST00000347667ABCG1chr2143708422+BACE2chr2142598193+0.0003053090.9996947
ENST00000343687ENST00000328735ABCG1chr2143708422+BACE2chr2142598193+0.0018009090.99819916
ENST00000343687ENST00000330333ABCG1chr2143708422+BACE2chr2142598193+0.0009467180.9990533
ENST00000343687ENST00000347667ABCG1chr2143708422+BACE2chr2142598193+0.0002840110.999716
ENST00000398437ENST00000328735ABCG1chr2143708422+BACE2chr2142598193+0.0011731410.9988268
ENST00000398437ENST00000330333ABCG1chr2143708422+BACE2chr2142598193+0.0004173910.9995826
ENST00000398437ENST00000347667ABCG1chr2143708422+BACE2chr2142598193+0.0002495010.99975055
ENST00000340588ENST00000328735ABCG1chr2143708422+BACE2chr2142598193+0.0014372960.99856275
ENST00000340588ENST00000330333ABCG1chr2143708422+BACE2chr2142598193+0.0005382860.9994617
ENST00000340588ENST00000347667ABCG1chr2143708422+BACE2chr2142598193+0.0003084130.9996916

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Fusion Genomic Features for ABCG1-BACE2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ABCG1chr2143708422+BACE2chr2142598192+0.0057778440.9942221
ABCG1chr2143708422+BACE2chr2142598192+0.0057778440.9942221

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ABCG1-BACE2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr21:43708422/chr21:42598193)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneABCG1chr21:43708422chr21:42598193ENST00000343687+101577_317419678.0DomainABC transporter
HgeneABCG1chr21:43708422chr21:42598193ENST00000347800+101577_317405664.0DomainABC transporter
HgeneABCG1chr21:43708422chr21:42598193ENST00000361802+101577_317420679.0DomainABC transporter
HgeneABCG1chr21:43708422chr21:42598193ENST00000398449+101577_317408667.0DomainABC transporter
HgeneABCG1chr21:43708422chr21:42598193ENST00000398457+111677_317410669.0DomainABC transporter
HgeneABCG1chr21:43708422chr21:42598193ENST00000343687+1015118_125419678.0Nucleotide bindingATP
HgeneABCG1chr21:43708422chr21:42598193ENST00000347800+1015118_125405664.0Nucleotide bindingATP
HgeneABCG1chr21:43708422chr21:42598193ENST00000361802+1015118_125420679.0Nucleotide bindingATP
HgeneABCG1chr21:43708422chr21:42598193ENST00000398449+1015118_125408667.0Nucleotide bindingATP
HgeneABCG1chr21:43708422chr21:42598193ENST00000398457+1116118_125410669.0Nucleotide bindingATP
TgeneBACE2chr21:43708422chr21:42598193ENST0000032873508495_518104397.0Topological domainCytoplasmic
TgeneBACE2chr21:43708422chr21:42598193ENST0000033033309495_518104519.0Topological domainCytoplasmic
TgeneBACE2chr21:43708422chr21:42598193ENST0000034766708495_518104469.0Topological domainCytoplasmic
TgeneBACE2chr21:43708422chr21:42598193ENST0000032873508474_494104397.0TransmembraneHelical
TgeneBACE2chr21:43708422chr21:42598193ENST0000033033309474_494104519.0TransmembraneHelical
TgeneBACE2chr21:43708422chr21:42598193ENST0000034766708474_494104469.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneABCG1chr21:43708422chr21:42598193ENST00000343687+1015415_673419678.0DomainNote=ABC transmembrane type-2
HgeneABCG1chr21:43708422chr21:42598193ENST00000347800+1015415_673405664.0DomainNote=ABC transmembrane type-2
HgeneABCG1chr21:43708422chr21:42598193ENST00000361802+1015415_673420679.0DomainNote=ABC transmembrane type-2
HgeneABCG1chr21:43708422chr21:42598193ENST00000398449+1015415_673408667.0DomainNote=ABC transmembrane type-2
HgeneABCG1chr21:43708422chr21:42598193ENST00000398457+1116415_673410669.0DomainNote=ABC transmembrane type-2
HgeneABCG1chr21:43708422chr21:42598193ENST00000343687+10151_426419678.0Topological domainCytoplasmic
HgeneABCG1chr21:43708422chr21:42598193ENST00000343687+1015446_456419678.0Topological domainExtracellular
HgeneABCG1chr21:43708422chr21:42598193ENST00000343687+1015478_506419678.0Topological domainCytoplasmic
HgeneABCG1chr21:43708422chr21:42598193ENST00000343687+1015526_533419678.0Topological domainExtracellular
HgeneABCG1chr21:43708422chr21:42598193ENST00000343687+1015556_567419678.0Topological domainCytoplasmic
HgeneABCG1chr21:43708422chr21:42598193ENST00000343687+1015587_649419678.0Topological domainExtracellular
HgeneABCG1chr21:43708422chr21:42598193ENST00000343687+1015670_678419678.0Topological domainCytoplasmic
HgeneABCG1chr21:43708422chr21:42598193ENST00000347800+10151_426405664.0Topological domainCytoplasmic
HgeneABCG1chr21:43708422chr21:42598193ENST00000347800+1015446_456405664.0Topological domainExtracellular
HgeneABCG1chr21:43708422chr21:42598193ENST00000347800+1015478_506405664.0Topological domainCytoplasmic
HgeneABCG1chr21:43708422chr21:42598193ENST00000347800+1015526_533405664.0Topological domainExtracellular
HgeneABCG1chr21:43708422chr21:42598193ENST00000347800+1015556_567405664.0Topological domainCytoplasmic
HgeneABCG1chr21:43708422chr21:42598193ENST00000347800+1015587_649405664.0Topological domainExtracellular
HgeneABCG1chr21:43708422chr21:42598193ENST00000347800+1015670_678405664.0Topological domainCytoplasmic
HgeneABCG1chr21:43708422chr21:42598193ENST00000361802+10151_426420679.0Topological domainCytoplasmic
HgeneABCG1chr21:43708422chr21:42598193ENST00000361802+1015446_456420679.0Topological domainExtracellular
HgeneABCG1chr21:43708422chr21:42598193ENST00000361802+1015478_506420679.0Topological domainCytoplasmic
HgeneABCG1chr21:43708422chr21:42598193ENST00000361802+1015526_533420679.0Topological domainExtracellular
HgeneABCG1chr21:43708422chr21:42598193ENST00000361802+1015556_567420679.0Topological domainCytoplasmic
HgeneABCG1chr21:43708422chr21:42598193ENST00000361802+1015587_649420679.0Topological domainExtracellular
HgeneABCG1chr21:43708422chr21:42598193ENST00000361802+1015670_678420679.0Topological domainCytoplasmic
HgeneABCG1chr21:43708422chr21:42598193ENST00000398449+10151_426408667.0Topological domainCytoplasmic
HgeneABCG1chr21:43708422chr21:42598193ENST00000398449+1015446_456408667.0Topological domainExtracellular
HgeneABCG1chr21:43708422chr21:42598193ENST00000398449+1015478_506408667.0Topological domainCytoplasmic
HgeneABCG1chr21:43708422chr21:42598193ENST00000398449+1015526_533408667.0Topological domainExtracellular
HgeneABCG1chr21:43708422chr21:42598193ENST00000398449+1015556_567408667.0Topological domainCytoplasmic
HgeneABCG1chr21:43708422chr21:42598193ENST00000398449+1015587_649408667.0Topological domainExtracellular
HgeneABCG1chr21:43708422chr21:42598193ENST00000398449+1015670_678408667.0Topological domainCytoplasmic
HgeneABCG1chr21:43708422chr21:42598193ENST00000398457+11161_426410669.0Topological domainCytoplasmic
HgeneABCG1chr21:43708422chr21:42598193ENST00000398457+1116446_456410669.0Topological domainExtracellular
HgeneABCG1chr21:43708422chr21:42598193ENST00000398457+1116478_506410669.0Topological domainCytoplasmic
HgeneABCG1chr21:43708422chr21:42598193ENST00000398457+1116526_533410669.0Topological domainExtracellular
HgeneABCG1chr21:43708422chr21:42598193ENST00000398457+1116556_567410669.0Topological domainCytoplasmic
HgeneABCG1chr21:43708422chr21:42598193ENST00000398457+1116587_649410669.0Topological domainExtracellular
HgeneABCG1chr21:43708422chr21:42598193ENST00000398457+1116670_678410669.0Topological domainCytoplasmic
HgeneABCG1chr21:43708422chr21:42598193ENST00000343687+1015427_445419678.0TransmembraneHelical
HgeneABCG1chr21:43708422chr21:42598193ENST00000343687+1015457_477419678.0TransmembraneHelical
HgeneABCG1chr21:43708422chr21:42598193ENST00000343687+1015507_525419678.0TransmembraneHelical
HgeneABCG1chr21:43708422chr21:42598193ENST00000343687+1015534_555419678.0TransmembraneHelical
HgeneABCG1chr21:43708422chr21:42598193ENST00000343687+1015568_586419678.0TransmembraneHelical
HgeneABCG1chr21:43708422chr21:42598193ENST00000343687+1015650_669419678.0TransmembraneHelical
HgeneABCG1chr21:43708422chr21:42598193ENST00000347800+1015427_445405664.0TransmembraneHelical
HgeneABCG1chr21:43708422chr21:42598193ENST00000347800+1015457_477405664.0TransmembraneHelical
HgeneABCG1chr21:43708422chr21:42598193ENST00000347800+1015507_525405664.0TransmembraneHelical
HgeneABCG1chr21:43708422chr21:42598193ENST00000347800+1015534_555405664.0TransmembraneHelical
HgeneABCG1chr21:43708422chr21:42598193ENST00000347800+1015568_586405664.0TransmembraneHelical
HgeneABCG1chr21:43708422chr21:42598193ENST00000347800+1015650_669405664.0TransmembraneHelical
HgeneABCG1chr21:43708422chr21:42598193ENST00000361802+1015427_445420679.0TransmembraneHelical
HgeneABCG1chr21:43708422chr21:42598193ENST00000361802+1015457_477420679.0TransmembraneHelical
HgeneABCG1chr21:43708422chr21:42598193ENST00000361802+1015507_525420679.0TransmembraneHelical
HgeneABCG1chr21:43708422chr21:42598193ENST00000361802+1015534_555420679.0TransmembraneHelical
HgeneABCG1chr21:43708422chr21:42598193ENST00000361802+1015568_586420679.0TransmembraneHelical
HgeneABCG1chr21:43708422chr21:42598193ENST00000361802+1015650_669420679.0TransmembraneHelical
HgeneABCG1chr21:43708422chr21:42598193ENST00000398449+1015427_445408667.0TransmembraneHelical
HgeneABCG1chr21:43708422chr21:42598193ENST00000398449+1015457_477408667.0TransmembraneHelical
HgeneABCG1chr21:43708422chr21:42598193ENST00000398449+1015507_525408667.0TransmembraneHelical
HgeneABCG1chr21:43708422chr21:42598193ENST00000398449+1015534_555408667.0TransmembraneHelical
HgeneABCG1chr21:43708422chr21:42598193ENST00000398449+1015568_586408667.0TransmembraneHelical
HgeneABCG1chr21:43708422chr21:42598193ENST00000398449+1015650_669408667.0TransmembraneHelical
HgeneABCG1chr21:43708422chr21:42598193ENST00000398457+1116427_445410669.0TransmembraneHelical
HgeneABCG1chr21:43708422chr21:42598193ENST00000398457+1116457_477410669.0TransmembraneHelical
HgeneABCG1chr21:43708422chr21:42598193ENST00000398457+1116507_525410669.0TransmembraneHelical
HgeneABCG1chr21:43708422chr21:42598193ENST00000398457+1116534_555410669.0TransmembraneHelical
HgeneABCG1chr21:43708422chr21:42598193ENST00000398457+1116568_586410669.0TransmembraneHelical
HgeneABCG1chr21:43708422chr21:42598193ENST00000398457+1116650_669410669.0TransmembraneHelical
TgeneBACE2chr21:43708422chr21:42598193ENST000003287350892_429104397.0DomainPeptidase A1
TgeneBACE2chr21:43708422chr21:42598193ENST000003303330992_429104519.0DomainPeptidase A1
TgeneBACE2chr21:43708422chr21:42598193ENST000003476670892_429104469.0DomainPeptidase A1
TgeneBACE2chr21:43708422chr21:42598193ENST000003287350821_473104397.0Topological domainExtracellular
TgeneBACE2chr21:43708422chr21:42598193ENST000003303330921_473104519.0Topological domainExtracellular
TgeneBACE2chr21:43708422chr21:42598193ENST000003476670821_473104469.0Topological domainExtracellular


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Fusion Gene Sequence for ABCG1-BACE2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>351_351_1_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000340588_BACE2_chr21_42598193_ENST00000328735_length(transcript)=3633nt_BP=1584nt
ATGGTCAGGAGAGGTTGGTCTGTCTGTACCGCCATTCTCTTGGCCAGACTGTGGTGTCTGGTCCCTACTCACACCTTCCTGTCAGAGTAT
CCAGAGGCCGCAGAGTATCCACACCCTGGCTGGGTGTACTGGCTACAGATGGCTGTGGCTCCAGGTCACCTGCGTGCCTGGGTGATGAGA
AATAATGTCACAACAAATATCCCATCTGCATTCTCTGGGACACTGACCCATGAAGAGAAAGCAGTTCTCACAGTTTTTACAGGCACAGCC
ACAGCCGTGCATGTACAGGTGGCAGCTTTAGCTTCTGCTAAACTGGAGAGCTCAGTGTTTGTGACAGACTGCGTGTCCTGCAAAATCGAA
AATGTCTGTGATTCAGCTCTTCAGGGAAAAAGGGTGCCGATGTCTGGCCTACAGGGCTCAAGCATTGTCATCATGCCCCCATCCAACCGT
CCACTCAAGGCCAGTGCGGCATCCTGCACGTGGTCAGTCCAAGTCCAGGGAGGGCCCCATCACCTGGGGGTGGTCGCTATCAGTGGCAAA
GTCTTGTCAGCAGCTCATGGGGCAGGAAGGGCCTATGGTTGGGGGTTTCCTGGCGATCCCATGGAGGAAGGATACAAGACCCTCCTGAAA
GGAATTTCCGGGAAGTTCAATAGTGGTGAGTTGGTGGCCATTATGGGTCCTTCCGGGGCCGGGAAGTCCACGCTGATGAACATCCTGGCT
GGATACAGGGAGACGGGCATGAAGGGGGCCGTCCTCATCAACGGCCTGCCCCGGGACCTGCGCTGCTTCCGGAAGGTGTCCTGCTACATC
ATGCAGGATGACATGCTGCTGCCGCATCTCACTGTGCAGGAGGCCATGATGGTGTCGGCACATCTGAAGCTTCAGGAGAAGGATGAAGGC
AGAAGGGAAATGGTCAAGGAGATACTGACAGCGCTGGGCTTGCTGTCTTGCGCCAACACGCGGACCGGGAGCCTGTCAGGTGGTCAGCGC
AAGCGCCTGGCCATCGCGCTGGAGCTGGTGAACAACCCTCCAGTCATGTTCTTCGATGAGCCCACCAGCGGCCTGGACAGCGCCTCCTGC
TTCCAGGTGGTCTCGCTGATGAAAGGGCTCGCTCAAGGGGGTCGCTCCATCATTTGCACCATCCACCAGCCCAGCGCCAAACTCTTCGAG
CTGTTCGACCAGCTTTACGTCCTGAGTCAAGGACAATGTGTGTACCGGGGAAAAGTCTGCAATCTTGTGCCATATTTGAGGGATTTGGGT
CTGAACTGCCCAACCTACCACAACCCAGCAGATTTTGTCATGGAGGTTGCATCCGGCGAGTACGGTGATCAGAACAGTCGGCTGGTGAGA
GCGGTTCGGGAGGGCATGTGTGACTCAGACCACAAGAGAGACCTCGGGGGTGATGCCGAGGTGAACCCTTTTCTTTGGCACCGGCCCTCT
GAAGAGGTAAAGCAGACAAAACGATTAAAGGGGTTGAGAAAGGACTCCTCGTCCATGGAAGGCTGCCACAGCTTCTCTGCCAGCTGCCTC
ACGCAGTTCTGCATCCTCTTCAAGAGGACCTTCCTCAGCATCATGAGGGACTCGCTACAGATTCTCGTTGACACTGGAAGCAGTAACTTT
GCCGTGGCAGGAACCCCGCACTCCTACATAGACACGTACTTTGACACAGAGAGGTCTAGCACATACCGCTCCAAGGGCTTTGACGTCACA
GTGAAGTACACACAAGGAAGCTGGACGGGCTTCGTTGGGGAAGACCTCGTCACCATCCCCAAAGGCTTCAATACTTCTTTTCTTGTCAAC
ATTGCCACTATTTTTGAATCAGAGAATTTCTTTTTGCCTGGGATTAAATGGAATGGAATACTTGGCCTAGCTTATGCCACACTTGCCAAG
CCATCAAGTTCTCTGGAGACCTTCTTCGACTCCCTGGTGACACAAGCAAACATCCCCAACGTTTTCTCCATGCAGATGTGTGGAGCCGGC
TTGCCCGTTGCTGGATCTGGGACCAACGGAGGTAGTCTTGTCTTGGGTGGAATTGAACCAAGTTTGTATAAAGGAGACATCTGGTATACC
CCTATTAAGGAAGAGTGGTACTACCAGATAGAAATTCTGAAATTGGAAATTGGAGGCCAAAGCCTTAATCTGGACTGCAGAGAGTATAAC
GCAGACAAGGCCATCGTGGACAGTGGCACCACGCTGCTGCGCCTGCCCCAGAAGGTGTTTGATGCGGTGGTGGAAGCTGTGGCCCGCGCA
TCTCTGATTCCAGAATTCTCTGATGGTTTCTGGACTGGGTCCCAGCTGGCGTGCTGGACGAATTCGGAAACACCTTGGTCTTACTTCCCT
AAAATCTCCATCTACCTGAGAGACGAGAACTCCAGCAGGTCATTCCGTATCACAATCCTGCCTCAGAAATTGCAGGTGCTGCAGTGTCTG
AAATTTCCGGGCCTTTCTCAACAGAGGATGTAGCCAGCAACTGTGTCCCCGCTCAGTCTTTGAGCGAGCCCATTTTGTGGATTGTGTCCT
ATGCGCTCATGAGCGTCTGTGGAGCCATCCTCCTTGTCTTAATCGTCCTGCTGCTGCTGCCGTTCCGGTGTCAGCGTCGCCCCCGTGACC
CTGAGGTCGTCAATGATGAGTCCTCTCTGGTCAGACATCGCTGGAAATGAATAGCCAGGCCTGACCTCAAGCAACCATGAACTCAGCTAT
TAAGAAAATCACATTTCCAGGGCAGCAGCCGGGATCGATGGTGGCGCTTTCTCCTGTGCCCACCCGTCTTCAATCTCTGTTCTGCTCCCA
GATGCCTTCTAGATTCACTGTCTTTTGATTCTTGATTTTCAAGCTTTCAAATCCTCCCTACTTCCAAGAAAAATAATTAAAAAAAAAACT
TCATTCTAAACCAAAACAGAGTGGATTGGGCTGCAGGCTCTATGGGGTTCGTTATGCCAAAGTGTCTACATGTGCCACCAACATAAAACA
AAACCAAGCCTTGGCTCGTTCTCTTCTCTCTTCAATCTCTGGAAAAATAAGTACATATAGTTGATAACCCCTCTTAGCTTACAGGAAGCT
TTTTGTATTAATTGCCTTTGAGGTTATTTTCCGCCAGACCTCAACCTGGGTCAAAGTGGTACAGGAAGGCTTGCAGTATGATGGCAGGAG
AATCAGCCTGGGGCCTGGGGATGTAACCAAGCTGTACCCTTGAGACCTGGAACCAGAGCCACAGGCCCCTTTTGTGGGTTTCTCTGTGCT
CTGAATGGGAGCCAGAATTCACTAGGAGGTCATCAACCGATGGTCCTCACAAGCCTCTTCTGAAGATGGAAGGCCTTTTGCCCGTTGAGG
TAGAGGGGAAGGAAATCTCCTCTTTTGTACCCAATACTTATGTTGTATTGTTGGTGCGAAAGTAAAAACACTACCTCTTTTGAGACTTTG
CCCAGGGTCCTGTGCCTGGATGGGGGTGCAGGCAGCCTTGACCACGGCTGTTCCCCTCACCCAAAAGAATTATCATCCCAACAGCCAAGA
CCCAACAGGTGCTGAACTGTGCATCAACCAGGAAGAGTTCTATCCCCAAGCTGGCCACTATCACATATGCTTACTCTTGCTTAAAATTAA

>351_351_1_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000340588_BACE2_chr21_42598193_ENST00000328735_length(amino acids)=820AA_BP=528
MVRRGWSVCTAILLARLWCLVPTHTFLSEYPEAAEYPHPGWVYWLQMAVAPGHLRAWVMRNNVTTNIPSAFSGTLTHEEKAVLTVFTGTA
TAVHVQVAALASAKLESSVFVTDCVSCKIENVCDSALQGKRVPMSGLQGSSIVIMPPSNRPLKASAASCTWSVQVQGGPHHLGVVAISGK
VLSAAHGAGRAYGWGFPGDPMEEGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYI
MQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASC
FQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVR
AVREGMCDSDHKRDLGGDAEVNPFLWHRPSEEVKQTKRLKGLRKDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSLQILVDTGSSNF
AVAGTPHSYIDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLAK
PSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYN
ADKAIVDSGTTLLRLPQKVFDAVVEAVARASLIPEFSDGFWTGSQLACWTNSETPWSYFPKISIYLRDENSSRSFRITILPQKLQVLQCL

--------------------------------------------------------------
>351_351_2_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000340588_BACE2_chr21_42598193_ENST00000330333_length(transcript)=3802nt_BP=1584nt
ATGGTCAGGAGAGGTTGGTCTGTCTGTACCGCCATTCTCTTGGCCAGACTGTGGTGTCTGGTCCCTACTCACACCTTCCTGTCAGAGTAT
CCAGAGGCCGCAGAGTATCCACACCCTGGCTGGGTGTACTGGCTACAGATGGCTGTGGCTCCAGGTCACCTGCGTGCCTGGGTGATGAGA
AATAATGTCACAACAAATATCCCATCTGCATTCTCTGGGACACTGACCCATGAAGAGAAAGCAGTTCTCACAGTTTTTACAGGCACAGCC
ACAGCCGTGCATGTACAGGTGGCAGCTTTAGCTTCTGCTAAACTGGAGAGCTCAGTGTTTGTGACAGACTGCGTGTCCTGCAAAATCGAA
AATGTCTGTGATTCAGCTCTTCAGGGAAAAAGGGTGCCGATGTCTGGCCTACAGGGCTCAAGCATTGTCATCATGCCCCCATCCAACCGT
CCACTCAAGGCCAGTGCGGCATCCTGCACGTGGTCAGTCCAAGTCCAGGGAGGGCCCCATCACCTGGGGGTGGTCGCTATCAGTGGCAAA
GTCTTGTCAGCAGCTCATGGGGCAGGAAGGGCCTATGGTTGGGGGTTTCCTGGCGATCCCATGGAGGAAGGATACAAGACCCTCCTGAAA
GGAATTTCCGGGAAGTTCAATAGTGGTGAGTTGGTGGCCATTATGGGTCCTTCCGGGGCCGGGAAGTCCACGCTGATGAACATCCTGGCT
GGATACAGGGAGACGGGCATGAAGGGGGCCGTCCTCATCAACGGCCTGCCCCGGGACCTGCGCTGCTTCCGGAAGGTGTCCTGCTACATC
ATGCAGGATGACATGCTGCTGCCGCATCTCACTGTGCAGGAGGCCATGATGGTGTCGGCACATCTGAAGCTTCAGGAGAAGGATGAAGGC
AGAAGGGAAATGGTCAAGGAGATACTGACAGCGCTGGGCTTGCTGTCTTGCGCCAACACGCGGACCGGGAGCCTGTCAGGTGGTCAGCGC
AAGCGCCTGGCCATCGCGCTGGAGCTGGTGAACAACCCTCCAGTCATGTTCTTCGATGAGCCCACCAGCGGCCTGGACAGCGCCTCCTGC
TTCCAGGTGGTCTCGCTGATGAAAGGGCTCGCTCAAGGGGGTCGCTCCATCATTTGCACCATCCACCAGCCCAGCGCCAAACTCTTCGAG
CTGTTCGACCAGCTTTACGTCCTGAGTCAAGGACAATGTGTGTACCGGGGAAAAGTCTGCAATCTTGTGCCATATTTGAGGGATTTGGGT
CTGAACTGCCCAACCTACCACAACCCAGCAGATTTTGTCATGGAGGTTGCATCCGGCGAGTACGGTGATCAGAACAGTCGGCTGGTGAGA
GCGGTTCGGGAGGGCATGTGTGACTCAGACCACAAGAGAGACCTCGGGGGTGATGCCGAGGTGAACCCTTTTCTTTGGCACCGGCCCTCT
GAAGAGGTAAAGCAGACAAAACGATTAAAGGGGTTGAGAAAGGACTCCTCGTCCATGGAAGGCTGCCACAGCTTCTCTGCCAGCTGCCTC
ACGCAGTTCTGCATCCTCTTCAAGAGGACCTTCCTCAGCATCATGAGGGACTCGCTACAGATTCTCGTTGACACTGGAAGCAGTAACTTT
GCCGTGGCAGGAACCCCGCACTCCTACATAGACACGTACTTTGACACAGAGAGGTCTAGCACATACCGCTCCAAGGGCTTTGACGTCACA
GTGAAGTACACACAAGGAAGCTGGACGGGCTTCGTTGGGGAAGACCTCGTCACCATCCCCAAAGGCTTCAATACTTCTTTTCTTGTCAAC
ATTGCCACTATTTTTGAATCAGAGAATTTCTTTTTGCCTGGGATTAAATGGAATGGAATACTTGGCCTAGCTTATGCCACACTTGCCAAG
CCATCAAGTTCTCTGGAGACCTTCTTCGACTCCCTGGTGACACAAGCAAACATCCCCAACGTTTTCTCCATGCAGATGTGTGGAGCCGGC
TTGCCCGTTGCTGGATCTGGGACCAACGGAGGTAGTCTTGTCTTGGGTGGAATTGAACCAAGTTTGTATAAAGGAGACATCTGGTATACC
CCTATTAAGGAAGAGTGGTACTACCAGATAGAAATTCTGAAATTGGAAATTGGAGGCCAAAGCCTTAATCTGGACTGCAGAGAGTATAAC
GCAGACAAGGCCATCGTGGACAGTGGCACCACGCTGCTGCGCCTGCCCCAGAAGGTGTTTGATGCGGTGGTGGAAGCTGTGGCCCGCGCA
TCTCTGATTCCAGAATTCTCTGATGGTTTCTGGACTGGGTCCCAGCTGGCGTGCTGGACGAATTCGGAAACACCTTGGTCTTACTTCCCT
AAAATCTCCATCTACCTGAGAGACGAGAACTCCAGCAGGTCATTCCGTATCACAATCCTGCCTCAGCTTTACATTCAGCCCATGATGGGG
GCCGGCCTGAATTATGAATGTTACCGATTCGGCATTTCCCCATCCACAAATGCGCTGGTGATCGGTGCCACGGTGATGGAGGGCTTCTAC
GTCATCTTCGACAGAGCCCAGAAGAGGGTGGGCTTCGCAGCGAGCCCCTGTGCAGAAATTGCAGGTGCTGCAGTGTCTGAAATTTCCGGG
CCTTTCTCAACAGAGGATGTAGCCAGCAACTGTGTCCCCGCTCAGTCTTTGAGCGAGCCCATTTTGTGGATTGTGTCCTATGCGCTCATG
AGCGTCTGTGGAGCCATCCTCCTTGTCTTAATCGTCCTGCTGCTGCTGCCGTTCCGGTGTCAGCGTCGCCCCCGTGACCCTGAGGTCGTC
AATGATGAGTCCTCTCTGGTCAGACATCGCTGGAAATGAATAGCCAGGCCTGACCTCAAGCAACCATGAACTCAGCTATTAAGAAAATCA
CATTTCCAGGGCAGCAGCCGGGATCGATGGTGGCGCTTTCTCCTGTGCCCACCCGTCTTCAATCTCTGTTCTGCTCCCAGATGCCTTCTA
GATTCACTGTCTTTTGATTCTTGATTTTCAAGCTTTCAAATCCTCCCTACTTCCAAGAAAAATAATTAAAAAAAAAACTTCATTCTAAAC
CAAAACAGAGTGGATTGGGCTGCAGGCTCTATGGGGTTCGTTATGCCAAAGTGTCTACATGTGCCACCAACATAAAACAAAACCAAGCCT
TGGCTCGTTCTCTTCTCTCTTCAATCTCTGGAAAAATAAGTACATATAGTTGATAACCCCTCTTAGCTTACAGGAAGCTTTTTGTATTAA
TTGCCTTTGAGGTTATTTTCCGCCAGACCTCAACCTGGGTCAAAGTGGTACAGGAAGGCTTGCAGTATGATGGCAGGAGAATCAGCCTGG
GGCCTGGGGATGTAACCAAGCTGTACCCTTGAGACCTGGAACCAGAGCCACAGGCCCCTTTTGTGGGTTTCTCTGTGCTCTGAATGGGAG
CCAGAATTCACTAGGAGGTCATCAACCGATGGTCCTCACAAGCCTCTTCTGAAGATGGAAGGCCTTTTGCCCGTTGAGGTAGAGGGGAAG
GAAATCTCCTCTTTTGTACCCAATACTTATGTTGTATTGTTGGTGCGAAAGTAAAAACACTACCTCTTTTGAGACTTTGCCCAGGGTCCT
GTGCCTGGATGGGGGTGCAGGCAGCCTTGACCACGGCTGTTCCCCTCACCCAAAAGAATTATCATCCCAACAGCCAAGACCCAACAGGTG
CTGAACTGTGCATCAACCAGGAAGAGTTCTATCCCCAAGCTGGCCACTATCACATATGCTTACTCTTGCTTAAAATTAATAAATCATGTT

>351_351_2_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000340588_BACE2_chr21_42598193_ENST00000330333_length(amino acids)=942AA_BP=528
MVRRGWSVCTAILLARLWCLVPTHTFLSEYPEAAEYPHPGWVYWLQMAVAPGHLRAWVMRNNVTTNIPSAFSGTLTHEEKAVLTVFTGTA
TAVHVQVAALASAKLESSVFVTDCVSCKIENVCDSALQGKRVPMSGLQGSSIVIMPPSNRPLKASAASCTWSVQVQGGPHHLGVVAISGK
VLSAAHGAGRAYGWGFPGDPMEEGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYI
MQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASC
FQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVR
AVREGMCDSDHKRDLGGDAEVNPFLWHRPSEEVKQTKRLKGLRKDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSLQILVDTGSSNF
AVAGTPHSYIDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLAK
PSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYN
ADKAIVDSGTTLLRLPQKVFDAVVEAVARASLIPEFSDGFWTGSQLACWTNSETPWSYFPKISIYLRDENSSRSFRITILPQLYIQPMMG
AGLNYECYRFGISPSTNALVIGATVMEGFYVIFDRAQKRVGFAASPCAEIAGAAVSEISGPFSTEDVASNCVPAQSLSEPILWIVSYALM

--------------------------------------------------------------
>351_351_3_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000340588_BACE2_chr21_42598193_ENST00000347667_length(transcript)=9573nt_BP=1584nt
ATGGTCAGGAGAGGTTGGTCTGTCTGTACCGCCATTCTCTTGGCCAGACTGTGGTGTCTGGTCCCTACTCACACCTTCCTGTCAGAGTAT
CCAGAGGCCGCAGAGTATCCACACCCTGGCTGGGTGTACTGGCTACAGATGGCTGTGGCTCCAGGTCACCTGCGTGCCTGGGTGATGAGA
AATAATGTCACAACAAATATCCCATCTGCATTCTCTGGGACACTGACCCATGAAGAGAAAGCAGTTCTCACAGTTTTTACAGGCACAGCC
ACAGCCGTGCATGTACAGGTGGCAGCTTTAGCTTCTGCTAAACTGGAGAGCTCAGTGTTTGTGACAGACTGCGTGTCCTGCAAAATCGAA
AATGTCTGTGATTCAGCTCTTCAGGGAAAAAGGGTGCCGATGTCTGGCCTACAGGGCTCAAGCATTGTCATCATGCCCCCATCCAACCGT
CCACTCAAGGCCAGTGCGGCATCCTGCACGTGGTCAGTCCAAGTCCAGGGAGGGCCCCATCACCTGGGGGTGGTCGCTATCAGTGGCAAA
GTCTTGTCAGCAGCTCATGGGGCAGGAAGGGCCTATGGTTGGGGGTTTCCTGGCGATCCCATGGAGGAAGGATACAAGACCCTCCTGAAA
GGAATTTCCGGGAAGTTCAATAGTGGTGAGTTGGTGGCCATTATGGGTCCTTCCGGGGCCGGGAAGTCCACGCTGATGAACATCCTGGCT
GGATACAGGGAGACGGGCATGAAGGGGGCCGTCCTCATCAACGGCCTGCCCCGGGACCTGCGCTGCTTCCGGAAGGTGTCCTGCTACATC
ATGCAGGATGACATGCTGCTGCCGCATCTCACTGTGCAGGAGGCCATGATGGTGTCGGCACATCTGAAGCTTCAGGAGAAGGATGAAGGC
AGAAGGGAAATGGTCAAGGAGATACTGACAGCGCTGGGCTTGCTGTCTTGCGCCAACACGCGGACCGGGAGCCTGTCAGGTGGTCAGCGC
AAGCGCCTGGCCATCGCGCTGGAGCTGGTGAACAACCCTCCAGTCATGTTCTTCGATGAGCCCACCAGCGGCCTGGACAGCGCCTCCTGC
TTCCAGGTGGTCTCGCTGATGAAAGGGCTCGCTCAAGGGGGTCGCTCCATCATTTGCACCATCCACCAGCCCAGCGCCAAACTCTTCGAG
CTGTTCGACCAGCTTTACGTCCTGAGTCAAGGACAATGTGTGTACCGGGGAAAAGTCTGCAATCTTGTGCCATATTTGAGGGATTTGGGT
CTGAACTGCCCAACCTACCACAACCCAGCAGATTTTGTCATGGAGGTTGCATCCGGCGAGTACGGTGATCAGAACAGTCGGCTGGTGAGA
GCGGTTCGGGAGGGCATGTGTGACTCAGACCACAAGAGAGACCTCGGGGGTGATGCCGAGGTGAACCCTTTTCTTTGGCACCGGCCCTCT
GAAGAGGTAAAGCAGACAAAACGATTAAAGGGGTTGAGAAAGGACTCCTCGTCCATGGAAGGCTGCCACAGCTTCTCTGCCAGCTGCCTC
ACGCAGTTCTGCATCCTCTTCAAGAGGACCTTCCTCAGCATCATGAGGGACTCGCTACAGATTCTCGTTGACACTGGAAGCAGTAACTTT
GCCGTGGCAGGAACCCCGCACTCCTACATAGACACGTACTTTGACACAGAGAGGTCTAGCACATACCGCTCCAAGGGCTTTGACGTCACA
GTGAAGTACACACAAGGAAGCTGGACGGGCTTCGTTGGGGAAGACCTCGTCACCATCCCCAAAGGCTTCAATACTTCTTTTCTTGTCAAC
ATTGCCACTATTTTTGAATCAGAGAATTTCTTTTTGCCTGGGATTAAATGGAATGGAATACTTGGCCTAGCTTATGCCACACTTGCCAAG
CCATCAAGTTCTCTGGAGACCTTCTTCGACTCCCTGGTGACACAAGCAAACATCCCCAACGTTTTCTCCATGCAGATGTGTGGAGCCGGC
TTGCCCGTTGCTGGATCTGGGACCAACGGAGGTAGTCTTGTCTTGGGTGGAATTGAACCAAGTTTGTATAAAGGAGACATCTGGTATACC
CCTATTAAGGAAGAGTGGTACTACCAGATAGAAATTCTGAAATTGGAAATTGGAGGCCAAAGCCTTAATCTGGACTGCAGAGAGTATAAC
GCAGACAAGGCCATCGTGGACAGTGGCACCACGCTGCTGCGCCTGCCCCAGAAGGTGTTTGATGCGGTGGTGGAAGCTGTGGCCCGCGCA
TCTCTGCTTTACATTCAGCCCATGATGGGGGCCGGCCTGAATTATGAATGTTACCGATTCGGCATTTCCCCATCCACAAATGCGCTGGTG
ATCGGTGCCACGGTGATGGAGGGCTTCTACGTCATCTTCGACAGAGCCCAGAAGAGGGTGGGCTTCGCAGCGAGCCCCTGTGCAGAAATT
GCAGGTGCTGCAGTGTCTGAAATTTCCGGGCCTTTCTCAACAGAGGATGTAGCCAGCAACTGTGTCCCCGCTCAGTCTTTGAGCGAGCCC
ATTTTGTGGATTGTGTCCTATGCGCTCATGAGCGTCTGTGGAGCCATCCTCCTTGTCTTAATCGTCCTGCTGCTGCTGCCGTTCCGGTGT
CAGCGTCGCCCCCGTGACCCTGAGGTCGTCAATGATGAGTCCTCTCTGGTCAGACATCGCTGGAAATGAATAGCCAGGCCTGACCTCAAG
CAACCATGAACTCAGCTATTAAGAAAATCACATTTCCAGGGCAGCAGCCGGGATCGATGGTGGCGCTTTCTCCTGTGCCCACCCGTCTTC
AATCTCTGTTCTGCTCCCAGATGCCTTCTAGATTCACTGTCTTTTGATTCTTGATTTTCAAGCTTTCAAATCCTCCCTACTTCCAAGAAA
AATAATTAAAAAAAAAACTTCATTCTAAACCAAAACAGAGTGGATTGGGCTGCAGGCTCTATGGGGTTCGTTATGCCAAAGTGTCTACAT
GTGCCACCAACATAAAACAAAACCAAGCCTTGGCTCGTTCTCTTCTCTCTTCAATCTCTGGAAAAATAAGTACATATAGTTGATAACCCC
TCTTAGCTTACAGGAAGCTTTTTGTATTAATTGCCTTTGAGGTTATTTTCCGCCAGACCTCAACCTGGGTCAAAGTGGTACAGGAAGGCT
TGCAGTATGATGGCAGGAGAATCAGCCTGGGGCCTGGGGATGTAACCAAGCTGTACCCTTGAGACCTGGAACCAGAGCCACAGGCCCCTT
TTGTGGGTTTCTCTGTGCTCTGAATGGGAGCCAGAATTCACTAGGAGGTCATCAACCGATGGTCCTCACAAGCCTCTTCTGAAGATGGAA
GGCCTTTTGCCCGTTGAGGTAGAGGGGAAGGAAATCTCCTCTTTTGTACCCAATACTTATGTTGTATTGTTGGTGCGAAAGTAAAAACAC
TACCTCTTTTGAGACTTTGCCCAGGGTCCTGTGCCTGGATGGGGGTGCAGGCAGCCTTGACCACGGCTGTTCCCCTCACCCAAAAGAATT
ATCATCCCAACAGCCAAGACCCAACAGGTGCTGAACTGTGCATCAACCAGGAAGAGTTCTATCCCCAAGCTGGCCACTATCACATATGCT
TACTCTTGCTTAAAATTAATAAATCATGTTTTGATGAGAAAAAACTATTCTATTTCACTAGCTTAGTTGTCTCTTTTTCCAAATCTTCTC
TGGAAGTAGGTTGGCTATTACCCTGTTGGGAAACAGGGAAATGGCCTGATGCCCCTATTTCTGACCAGCTGTCAGGGAAGGAAGATGCAA
GATGTGCAGAAGACACAAGGTAACGTCTACTTATCCCCGTGCTTCGAAACCGTGTGTTTCCCTTTGCAGAACTGGTTAGCCTCAAGCATA
CCCATCCAATCAGCTTAAATTGTTCAGCAGTTGACCTCTGTGCTTCTTCCTTTGGGGGTGTTTAATCTTTGGTAACAGTTGTGCAGTGGT
AGCCTTATTTCGGGGGGCAGTCCCTACTTTCTGTCACTTATCGAGGCCTTTGCCAAAGAAAAGTGGAAGCCGTTTCCTTGACATAGCCTT
ATATGACCTGATGTCATTAGGAGAAGAGTTAAAAGACAGTATCCCCTCTCTCCTGCTTGTGTGCCAAGTTCAGTGTTCCCTTTGCATTTT
TTTGGGGTGGGTTGGCTATATTACAGAATTCCACCAAAAGTGCTAAGTGTCCCCTCCTGCAGAAGTATCGTTTGTATTCACAGTAGGCTA
CGTGTGGATGTTTCAGCCATCTGCTCTGCTCCCTGGGTCCCCGGGTCACCACCATACTGAGAAATATAGGACTCTGCCAAAGAGACGTGG
AGGCCACGTCGGCTTGTCATGGTGTCCTGGAAGACTCTCCAGCAGCCAGAAGAACCTTCTGTGCTGTTTTCACTAGAGAAGATTTGAGTT
GCAGCCTCTTGGAAAGAACATGACGGCACGGAACGGGAGGAGGGGGCTCTTGTATCAGGGCCCGTTGTCACATCCGCTCTCAGCTTGTTG
AAAACTCATAATCTCAGAATGCATTTCACACGGAGAGATGTCTGGAAGTCCAATTCTCATCCCATTGGCTTTTTCCGTGGTTGCTGTTTT
GTGGGCCGCTTTGCACAGGAGTGAAGCCAACACCCCTAGATTGTGCCTTCACCCTTGCTGTGAAAAATTCAAAGCCCTGAAATAAGAGGA
GGGAATCGCAGACATGCCCTGATTAGTTTTCCTGCTTATTTCTTCATACAGGCATCTTCTGTTCCGTTGTATTGTGTTAGGTTTCAGAGG
CGGGGAGCTTCCTCCTGCAGCAGATGAACAGGCATAGTTCTTAAAATACAGGAAAGTAACAAGTGAGGTTTCCAGGTAGAGTAGGTGAAT
GAAGTTTGCCGTCATGCTCTGTATTTCATATCAGATTTCTTTATCTTTTCATATCGCATGTCATTGGATGTGACATTTTGATGAAAATAC
TGAAACTACAAAAGCATAACTTCGCAACAAGAATGAGATAGACAATTGAATGTGGGACATTTTTCTGGCATGTCTTGCTGCTGAGAATCG
GACTTCCAGTCAAAACCCTGTTAGTGACACCCACCTCCTCCAGTTATGCAAATTGATGCTTAGCTTGGCAAGCTTTCAAGGAGGTTTGCT
TGGAACAGGAAAGGAATTAACAACCCTTTGAGGGTGTCATTTTTACCTTGTAATACACTGTGGAAAATTCTGGAAGACGGTCCTTGCCTG
AAAAGGTGCAACTTAGCATTAGGTTGTTATCAGAAACCTTGTCAAGTCTGATGGGAAATGAATAGATGCTGCTTTATTTCCTTGATAACT
TCTTTGGAAGTCTGAAATAAATCCTGCCTTCAGTAACTGAAACCATTTATTAAAAATAGCAAGAAACAAGATGGGGACCAATTCTATTTT
TATTCTTGGGAATTTGAAAGAGCCACAAGTGATTGGTGTCCGATCTCCCAGCATATACTGTACACTATTTTGTATTTCTCCTGAACCAAA
ACCAAGTACTTAGCACTCAAGAAACAGATGCCCTGTGTGTGACCGAGGGGAGTGTTTTTCCACAACAGGTTCCACTTCTGAACACTTGGA
AGGACCTTGCCTGATTCATGGTGAAACACAGAGGTTTTGGTTGGAGATAAATTTGGGGTCAGTTACTGTTCAAAATTGTGAAAGTAGTTC
CCAGGAAGACAGCATTAGTGACTCCGCAGTGCTTTGGGTAATAGATTTTGAAAAGCAATTGTGAGTTGGGGATTCCATCATTTCATTTAA
GAGGTGAAGAGGGATTTAATTATTTAATACGCCGGGTGCAAACTTGTTAAATTCCTCTTTCCCTGTCCCTGCTTGGTGGAGCTGCCACGT
GTGGTTCAGTTCTAAGTTCTGGACTAGTGCCACTCGATATCATTGGGAATAAATCGTTGTTCAACAGTCTGTTCCACAAACAACAGTAAT
TGAATTTCACAGACTTTATCCTGATTAGTGGAAATCAAATAATGGAGTGGAATCCCCATGTGTTTTCTCTTGCACAAACTTATTAGACTT
GATTAGAAAACTGTTTGGAGGAAAAACTTGCCAGTAAGTTTTTTGGTTGTTGTTTTGTTTTTTTTGAAAAACGACGCAACACCATAAAGT
GTAAAATTAGGGGTTCTGGCCAAGAGAGGTACTAGATTTTTTTAATGCCGAGAAAAGTCCATGCCACAGAAGTTATTGTGTATGTCTCTA
GGGAGCTTTAAGAATTTCACGTTTGAACTTTACAGCTGTTTACCAATTAAATGGCAAGCTGGAAAAATACATTTTGAGAGGGGTAGAAAG
AATAAGAATATAATTAAAAGTATGCTAACAAAATAAGCAGTACATATTTTTTTAGAAAATGCAGTTTAGGCCAGGCACGGTAGCTCGTGC
CTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGGACAACATGGTGAAACCCCG
TCTCTACTAAAAATACAAAAAATTAGCCAACGATGGTGATGCCTGTCTGTAATCCCAGCTACTCTGGAGGCTGAGGCAGGAGAATCGCTT
GAACCGGGGAGGCAGAGGTTGTAGTGAGCCAAGATTGCGCCACTGCACTCCAGCCTGGGCAACAGAGCAAGACTCCGTCTCAAAAAAGGA
AAGAAAATGCAGTTTCATTCCAGCCATCCTTAGATTTCTTTTCCCCTTAAAGTGGCTGAATCCATTGGAGATGTGATTTATTTTGCAGAT
CCACCAATTCCAAACTTCAGGAATATTCAAGCGGGAGTCATGTGTAAGTGACAGCTTTGACAAAGAGAGACTGTGGCTGGGTGGCCCGGG
TGTTGCCCACGCGGAGCAAGGATTGGTTCATTCAACGGATGGAGAGTACAGGATGGCTGGGACCTGGGAAGTTCCAGAATCTGAAAAGAG
GGCAGGGCAAGAAGGAGCCAGAAGAGAGGTCCCACCCCTCAGTTGGCAGTGGGGCACGGAGGTCCGCATCAGCCAAGAACGTCCCCAGGA
TGCCGTGGGCACCTCATTTCACCCCACGTTTTTGGCACAGTCTACTTTTTAGGTATTTTGTAAAGGAACTTCTCAGGATTGATTATTTGC
CAGAGGAACAATTAGGCCAAGAGAAACTTGCTTGACAGCCATGTGTAAAACACGTCTGTCCTAATCAAACTAGAGATGCCTCAAGGCCCA
CGCAGGACACAGGCAGGTTCAAGGTCATGCACCTGGAAATTTGTAGGGGAGGGTCAAGCAACTGAGGCCAAAGGGGGCCGGTAAAGTGGC
TTCTGGGGTCTGAGCATCTGGAAGGCTCCTGGCAGCAGTTACCTGACAGTGTCGTTGAGGGGCACGGCAGCTGGGCCCTCACCGTTTCCG
CCAGCTCTGCTGAGCCAGCCCAGCCCATGCATTCCGAACATCCGACAGCTTCTTTCTCCAGAATGTCTTCTGTCAGAGACTTCCAGGAAA
GGAGCTCCCTCCTGTCTCACTGCTGTCAGCGTGGGAGCCCTGCTCCCCAGGCTCCACGTCCCCGGAAGGTCCATCTTGTCCTGGAGCACA
CCCAGCCCCATTCAGGGTCAGTGCAGGAGGGAACAGGGAATCTGCATTTCAGTAAGCTCCCCAGGTGAGGCTGCAGAGCAGAAACCACGG
CTTTCAGACGTGAGCAGGCTCCCTGGGCTCTTGGTGTCACCCTGTTAGCCACATCTGCGGAATGTGGAAGGCAGAACATAGCCACGCTGC
TTAGTGCTGCCAGCGAACCTCAGGTTGCATCAGTGGCTGGAATCTATCACAGCTGTTGGGGATACGTAACTCCCAGCAATAAATCCAGTA
TTTTCTTCCCTGCCCTGAGCTTCCTCTGGGTTTCTTATCAGCAGCTATTACACACAGATGTCCAGTGCTTCTAAACTAAATTGTACTGTG
TAACTTTTACATCACACTTGTGTGCTTAAAAAGCACACCGTGGGTAGTGACTGGGCCAAGAGACATCACAAAGCTTCCTGATAAATTTGA
ATCCAGCCACGGCAAGAGCGACGTGCGGGTACCTGGTCCCTGATGCTTGGGTGCCCCGTTGAGCCTCGGGTACTTCTTGGACACTATTGT
GAGAGCAGCCATCCTGGTGTCTCTGCCAGCATCTTGGGGAACGCTGTGATGGTAAAATATCTGTCTCTCCTCTGGGAATCAGGGCAGCCC
TGAGAAGTGAGCAGTTCCCTTTACAGATGGATAATTGTTTGTGTAAGACCAACCAGATAAAGTCCAAACTGTGTAGAACACACGTGTGCC
TCACACATAGCCATCTGAGTAAAATATTTTTTCCAATGTAGATTTATAATTAGAAATGACAGATTTATAATATAGACTTCAGTAAGTTGG
GCACAGCTGTCACTTTCGTGGTATCAATAAAAGGCTAGAAACCTTGGGTGTCCTTGGCAACCTAGCCTTTGACATTGATGTTTTTCCATA
GGATTTTCTTCATTTGGGTTGGAATAAAAATGCATTTTTATTCACAAGGCACAGACAGATAAGAATATCATAAGCAGGGAAGTGTCTCCA
AAGGTCAGGACATATGTTTTTCTGTTGAGTGCTATATGTGGAGGTCATTGCAAGTTCCCTGATATGAGTATGGTTTCGCTTGCTACATTG
TGCCTATTAAAGTAAAATTTTACACAAGCCTCGCATTTCTAAGATTAGTGTTCCTGAATGAAATGTTAAGAAAACATTAAAAGATTATCT
CTTTTTAAGATGGAGGAAAAAAAGTGAACAAAGCTAATTAATCTATCATGAAAATTGCACAAAATAACATTTCTTAACAAATTTAATACA
ATTTTGTGTTCTTTGTTGCTAGTGGTATAAAACGAGATTTTTTTCCCTCATTTTTCTCATTGTAGATGTCATCTCTCACATTTATATCAG
TGAGGTTTGAAATTCTGTGTAGCAGTTACTCAGCACATATGAGAGGGCAGCGAATGAATGAGATTTGTCATGTGCTAATAAAAGCTGAAT
TTTTGTAATCTAAAATGATGTATTTTCTACTATTGCTGTTAATTTGCATTGTTAAAAATTCTTAAAGTTTAATATGTTATGTTCAGTCAT
TGAAAGCGACCACTCATTTTTTTCTTAAAGTTGATGCCTTTTCTGCTGTGCTAGAGTCAGTATTTTGCTTCTGGCAGGAGAGCTGCAAAC
TGTGTATCCTCAAACAGATGCAAAAAGTAGTGCTTTGCAAAACGTTTGTTTTCTGTTTATCTCAGATTAACATCCTTTAATACAAGTTTC
TTAAGTGTAACTTGTATTTCTGAAAATGCTTAAAATTATTTTATATTTCCCTTTGGGAATTTTTCTCTATTTCCAGCACGCTGATTTGAT
TTAAAAATGTAATAAGACCAAGAGTTGGAGTAAAGGGATATTCATTCCATGTTAAAAGTGGCTTCATAGCTACTGACAAATGTCTGAACT
ATTGTCGTGCCCTTCAAAACTGGAGTTTTCTAAAATAATCTTATTTTTATACTTGTATGTTCCAGCAATTTAAGATATATACCATTGAAA

>351_351_3_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000340588_BACE2_chr21_42598193_ENST00000347667_length(amino acids)=892AA_BP=528
MVRRGWSVCTAILLARLWCLVPTHTFLSEYPEAAEYPHPGWVYWLQMAVAPGHLRAWVMRNNVTTNIPSAFSGTLTHEEKAVLTVFTGTA
TAVHVQVAALASAKLESSVFVTDCVSCKIENVCDSALQGKRVPMSGLQGSSIVIMPPSNRPLKASAASCTWSVQVQGGPHHLGVVAISGK
VLSAAHGAGRAYGWGFPGDPMEEGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYI
MQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASC
FQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVR
AVREGMCDSDHKRDLGGDAEVNPFLWHRPSEEVKQTKRLKGLRKDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSLQILVDTGSSNF
AVAGTPHSYIDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLAK
PSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYN
ADKAIVDSGTTLLRLPQKVFDAVVEAVARASLLYIQPMMGAGLNYECYRFGISPSTNALVIGATVMEGFYVIFDRAQKRVGFAASPCAEI

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>351_351_4_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000343687_BACE2_chr21_42598193_ENST00000328735_length(transcript)=3457nt_BP=1408nt
AGCCTGCGACTGCACTCCCGGGGACACCCTCTCCCGGACCCACTCGGGGAGGCGGCGGCGAAGGCCCGGGGAGACCCGCGAGGGGCAAGC
CCGGATTCCTGCCGGCCGCCTTTCTGCGCGCGCCGGAGAGAGAGACGCGGTGGGGACAGGGATGCGCATTTCACTTCCCCGAGCTCCGGA
GAGGGATGGCGGGGTGTCGGCGAGTTCACTGCTGGACACAGTTACTAATGCCAGCAGTTACTCTGCAGAGATGACGGAGCCCAAGTCGGT
GTGTGTCTCGGTGGATGAGGTGGTGTCCAGCAACATGGAGGCCACTGAGACGGACCTGCTGAATGGACATCTGAAAAAAGTAGATAATAA
CCTCACGGAAGCCCAGCGCTTCTCCTCCTTGCCTCGGAGGGCAGCTGTGAACATTGAATTCAGGGACCTTTCCTATTCGGTTCCTGAAGG
ACCCTGGTGGAGGAAGAAAGGATACAAGACCCTCCTGAAAGGAATTTCCGGGAAGTTCAATAGTGGTGAGTTGGTGGCCATTATGGGTCC
TTCCGGGGCCGGGAAGTCCACGCTGATGAACATCCTGGCTGGATACAGGGAGACGGGCATGAAGGGGGCCGTCCTCATCAACGGCCTGCC
CCGGGACCTGCGCTGCTTCCGGAAGGTGTCCTGCTACATCATGCAGGATGACATGCTGCTGCCGCATCTCACTGTGCAGGAGGCCATGAT
GGTGTCGGCACATCTGAAGCTTCAGGAGAAGGATGAAGGCAGAAGGGAAATGGTCAAGGAGATACTGACAGCGCTGGGCTTGCTGTCTTG
CGCCAACACGCGGACCGGGAGCCTGTCAGGTGGTCAGCGCAAGCGCCTGGCCATCGCGCTGGAGCTGGTGAACAACCCTCCAGTCATGTT
CTTCGATGAGCCCACCAGCGGCCTGGACAGCGCCTCCTGCTTCCAGGTGGTCTCGCTGATGAAAGGGCTCGCTCAAGGGGGTCGCTCCAT
CATTTGCACCATCCACCAGCCCAGCGCCAAACTCTTCGAGCTGTTCGACCAGCTTTACGTCCTGAGTCAAGGACAATGTGTGTACCGGGG
AAAAGTCTGCAATCTTGTGCCATATTTGAGGGATTTGGGTCTGAACTGCCCAACCTACCACAACCCAGCAGATTTTGTCATGGAGGTTGC
ATCCGGCGAGTACGGTGATCAGAACAGTCGGCTGGTGAGAGCGGTTCGGGAGGGCATGTGTGACTCAGACCACAAGAGAGACCTCGGGGG
TGATGCCGAGGTGAACCCTTTTCTTTGGCACCGGCCCTCTGAAGAGGACTCCTCGTCCATGGAAGGCTGCCACAGCTTCTCTGCCAGCTG
CCTCACGCAGTTCTGCATCCTCTTCAAGAGGACCTTCCTCAGCATCATGAGGGACTCGCTACAGATTCTCGTTGACACTGGAAGCAGTAA
CTTTGCCGTGGCAGGAACCCCGCACTCCTACATAGACACGTACTTTGACACAGAGAGGTCTAGCACATACCGCTCCAAGGGCTTTGACGT
CACAGTGAAGTACACACAAGGAAGCTGGACGGGCTTCGTTGGGGAAGACCTCGTCACCATCCCCAAAGGCTTCAATACTTCTTTTCTTGT
CAACATTGCCACTATTTTTGAATCAGAGAATTTCTTTTTGCCTGGGATTAAATGGAATGGAATACTTGGCCTAGCTTATGCCACACTTGC
CAAGCCATCAAGTTCTCTGGAGACCTTCTTCGACTCCCTGGTGACACAAGCAAACATCCCCAACGTTTTCTCCATGCAGATGTGTGGAGC
CGGCTTGCCCGTTGCTGGATCTGGGACCAACGGAGGTAGTCTTGTCTTGGGTGGAATTGAACCAAGTTTGTATAAAGGAGACATCTGGTA
TACCCCTATTAAGGAAGAGTGGTACTACCAGATAGAAATTCTGAAATTGGAAATTGGAGGCCAAAGCCTTAATCTGGACTGCAGAGAGTA
TAACGCAGACAAGGCCATCGTGGACAGTGGCACCACGCTGCTGCGCCTGCCCCAGAAGGTGTTTGATGCGGTGGTGGAAGCTGTGGCCCG
CGCATCTCTGATTCCAGAATTCTCTGATGGTTTCTGGACTGGGTCCCAGCTGGCGTGCTGGACGAATTCGGAAACACCTTGGTCTTACTT
CCCTAAAATCTCCATCTACCTGAGAGACGAGAACTCCAGCAGGTCATTCCGTATCACAATCCTGCCTCAGAAATTGCAGGTGCTGCAGTG
TCTGAAATTTCCGGGCCTTTCTCAACAGAGGATGTAGCCAGCAACTGTGTCCCCGCTCAGTCTTTGAGCGAGCCCATTTTGTGGATTGTG
TCCTATGCGCTCATGAGCGTCTGTGGAGCCATCCTCCTTGTCTTAATCGTCCTGCTGCTGCTGCCGTTCCGGTGTCAGCGTCGCCCCCGT
GACCCTGAGGTCGTCAATGATGAGTCCTCTCTGGTCAGACATCGCTGGAAATGAATAGCCAGGCCTGACCTCAAGCAACCATGAACTCAG
CTATTAAGAAAATCACATTTCCAGGGCAGCAGCCGGGATCGATGGTGGCGCTTTCTCCTGTGCCCACCCGTCTTCAATCTCTGTTCTGCT
CCCAGATGCCTTCTAGATTCACTGTCTTTTGATTCTTGATTTTCAAGCTTTCAAATCCTCCCTACTTCCAAGAAAAATAATTAAAAAAAA
AACTTCATTCTAAACCAAAACAGAGTGGATTGGGCTGCAGGCTCTATGGGGTTCGTTATGCCAAAGTGTCTACATGTGCCACCAACATAA
AACAAAACCAAGCCTTGGCTCGTTCTCTTCTCTCTTCAATCTCTGGAAAAATAAGTACATATAGTTGATAACCCCTCTTAGCTTACAGGA
AGCTTTTTGTATTAATTGCCTTTGAGGTTATTTTCCGCCAGACCTCAACCTGGGTCAAAGTGGTACAGGAAGGCTTGCAGTATGATGGCA
GGAGAATCAGCCTGGGGCCTGGGGATGTAACCAAGCTGTACCCTTGAGACCTGGAACCAGAGCCACAGGCCCCTTTTGTGGGTTTCTCTG
TGCTCTGAATGGGAGCCAGAATTCACTAGGAGGTCATCAACCGATGGTCCTCACAAGCCTCTTCTGAAGATGGAAGGCCTTTTGCCCGTT
GAGGTAGAGGGGAAGGAAATCTCCTCTTTTGTACCCAATACTTATGTTGTATTGTTGGTGCGAAAGTAAAAACACTACCTCTTTTGAGAC
TTTGCCCAGGGTCCTGTGCCTGGATGGGGGTGCAGGCAGCCTTGACCACGGCTGTTCCCCTCACCCAAAAGAATTATCATCCCAACAGCC
AAGACCCAACAGGTGCTGAACTGTGCATCAACCAGGAAGAGTTCTATCCCCAAGCTGGCCACTATCACATATGCTTACTCTTGCTTAAAA

>351_351_4_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000343687_BACE2_chr21_42598193_ENST00000328735_length(amino acids)=711AA_BP=419
MRISLPRAPERDGGVSASSLLDTVTNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSLPRRAAVNIEF
RDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLL
PHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLM
KGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMC
DSDHKRDLGGDAEVNPFLWHRPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSLQILVDTGSSNFAVAGTPHSYIDTYFDTERS
STYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIP
NVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKV

--------------------------------------------------------------
>351_351_5_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000343687_BACE2_chr21_42598193_ENST00000330333_length(transcript)=3626nt_BP=1408nt
AGCCTGCGACTGCACTCCCGGGGACACCCTCTCCCGGACCCACTCGGGGAGGCGGCGGCGAAGGCCCGGGGAGACCCGCGAGGGGCAAGC
CCGGATTCCTGCCGGCCGCCTTTCTGCGCGCGCCGGAGAGAGAGACGCGGTGGGGACAGGGATGCGCATTTCACTTCCCCGAGCTCCGGA
GAGGGATGGCGGGGTGTCGGCGAGTTCACTGCTGGACACAGTTACTAATGCCAGCAGTTACTCTGCAGAGATGACGGAGCCCAAGTCGGT
GTGTGTCTCGGTGGATGAGGTGGTGTCCAGCAACATGGAGGCCACTGAGACGGACCTGCTGAATGGACATCTGAAAAAAGTAGATAATAA
CCTCACGGAAGCCCAGCGCTTCTCCTCCTTGCCTCGGAGGGCAGCTGTGAACATTGAATTCAGGGACCTTTCCTATTCGGTTCCTGAAGG
ACCCTGGTGGAGGAAGAAAGGATACAAGACCCTCCTGAAAGGAATTTCCGGGAAGTTCAATAGTGGTGAGTTGGTGGCCATTATGGGTCC
TTCCGGGGCCGGGAAGTCCACGCTGATGAACATCCTGGCTGGATACAGGGAGACGGGCATGAAGGGGGCCGTCCTCATCAACGGCCTGCC
CCGGGACCTGCGCTGCTTCCGGAAGGTGTCCTGCTACATCATGCAGGATGACATGCTGCTGCCGCATCTCACTGTGCAGGAGGCCATGAT
GGTGTCGGCACATCTGAAGCTTCAGGAGAAGGATGAAGGCAGAAGGGAAATGGTCAAGGAGATACTGACAGCGCTGGGCTTGCTGTCTTG
CGCCAACACGCGGACCGGGAGCCTGTCAGGTGGTCAGCGCAAGCGCCTGGCCATCGCGCTGGAGCTGGTGAACAACCCTCCAGTCATGTT
CTTCGATGAGCCCACCAGCGGCCTGGACAGCGCCTCCTGCTTCCAGGTGGTCTCGCTGATGAAAGGGCTCGCTCAAGGGGGTCGCTCCAT
CATTTGCACCATCCACCAGCCCAGCGCCAAACTCTTCGAGCTGTTCGACCAGCTTTACGTCCTGAGTCAAGGACAATGTGTGTACCGGGG
AAAAGTCTGCAATCTTGTGCCATATTTGAGGGATTTGGGTCTGAACTGCCCAACCTACCACAACCCAGCAGATTTTGTCATGGAGGTTGC
ATCCGGCGAGTACGGTGATCAGAACAGTCGGCTGGTGAGAGCGGTTCGGGAGGGCATGTGTGACTCAGACCACAAGAGAGACCTCGGGGG
TGATGCCGAGGTGAACCCTTTTCTTTGGCACCGGCCCTCTGAAGAGGACTCCTCGTCCATGGAAGGCTGCCACAGCTTCTCTGCCAGCTG
CCTCACGCAGTTCTGCATCCTCTTCAAGAGGACCTTCCTCAGCATCATGAGGGACTCGCTACAGATTCTCGTTGACACTGGAAGCAGTAA
CTTTGCCGTGGCAGGAACCCCGCACTCCTACATAGACACGTACTTTGACACAGAGAGGTCTAGCACATACCGCTCCAAGGGCTTTGACGT
CACAGTGAAGTACACACAAGGAAGCTGGACGGGCTTCGTTGGGGAAGACCTCGTCACCATCCCCAAAGGCTTCAATACTTCTTTTCTTGT
CAACATTGCCACTATTTTTGAATCAGAGAATTTCTTTTTGCCTGGGATTAAATGGAATGGAATACTTGGCCTAGCTTATGCCACACTTGC
CAAGCCATCAAGTTCTCTGGAGACCTTCTTCGACTCCCTGGTGACACAAGCAAACATCCCCAACGTTTTCTCCATGCAGATGTGTGGAGC
CGGCTTGCCCGTTGCTGGATCTGGGACCAACGGAGGTAGTCTTGTCTTGGGTGGAATTGAACCAAGTTTGTATAAAGGAGACATCTGGTA
TACCCCTATTAAGGAAGAGTGGTACTACCAGATAGAAATTCTGAAATTGGAAATTGGAGGCCAAAGCCTTAATCTGGACTGCAGAGAGTA
TAACGCAGACAAGGCCATCGTGGACAGTGGCACCACGCTGCTGCGCCTGCCCCAGAAGGTGTTTGATGCGGTGGTGGAAGCTGTGGCCCG
CGCATCTCTGATTCCAGAATTCTCTGATGGTTTCTGGACTGGGTCCCAGCTGGCGTGCTGGACGAATTCGGAAACACCTTGGTCTTACTT
CCCTAAAATCTCCATCTACCTGAGAGACGAGAACTCCAGCAGGTCATTCCGTATCACAATCCTGCCTCAGCTTTACATTCAGCCCATGAT
GGGGGCCGGCCTGAATTATGAATGTTACCGATTCGGCATTTCCCCATCCACAAATGCGCTGGTGATCGGTGCCACGGTGATGGAGGGCTT
CTACGTCATCTTCGACAGAGCCCAGAAGAGGGTGGGCTTCGCAGCGAGCCCCTGTGCAGAAATTGCAGGTGCTGCAGTGTCTGAAATTTC
CGGGCCTTTCTCAACAGAGGATGTAGCCAGCAACTGTGTCCCCGCTCAGTCTTTGAGCGAGCCCATTTTGTGGATTGTGTCCTATGCGCT
CATGAGCGTCTGTGGAGCCATCCTCCTTGTCTTAATCGTCCTGCTGCTGCTGCCGTTCCGGTGTCAGCGTCGCCCCCGTGACCCTGAGGT
CGTCAATGATGAGTCCTCTCTGGTCAGACATCGCTGGAAATGAATAGCCAGGCCTGACCTCAAGCAACCATGAACTCAGCTATTAAGAAA
ATCACATTTCCAGGGCAGCAGCCGGGATCGATGGTGGCGCTTTCTCCTGTGCCCACCCGTCTTCAATCTCTGTTCTGCTCCCAGATGCCT
TCTAGATTCACTGTCTTTTGATTCTTGATTTTCAAGCTTTCAAATCCTCCCTACTTCCAAGAAAAATAATTAAAAAAAAAACTTCATTCT
AAACCAAAACAGAGTGGATTGGGCTGCAGGCTCTATGGGGTTCGTTATGCCAAAGTGTCTACATGTGCCACCAACATAAAACAAAACCAA
GCCTTGGCTCGTTCTCTTCTCTCTTCAATCTCTGGAAAAATAAGTACATATAGTTGATAACCCCTCTTAGCTTACAGGAAGCTTTTTGTA
TTAATTGCCTTTGAGGTTATTTTCCGCCAGACCTCAACCTGGGTCAAAGTGGTACAGGAAGGCTTGCAGTATGATGGCAGGAGAATCAGC
CTGGGGCCTGGGGATGTAACCAAGCTGTACCCTTGAGACCTGGAACCAGAGCCACAGGCCCCTTTTGTGGGTTTCTCTGTGCTCTGAATG
GGAGCCAGAATTCACTAGGAGGTCATCAACCGATGGTCCTCACAAGCCTCTTCTGAAGATGGAAGGCCTTTTGCCCGTTGAGGTAGAGGG
GAAGGAAATCTCCTCTTTTGTACCCAATACTTATGTTGTATTGTTGGTGCGAAAGTAAAAACACTACCTCTTTTGAGACTTTGCCCAGGG
TCCTGTGCCTGGATGGGGGTGCAGGCAGCCTTGACCACGGCTGTTCCCCTCACCCAAAAGAATTATCATCCCAACAGCCAAGACCCAACA
GGTGCTGAACTGTGCATCAACCAGGAAGAGTTCTATCCCCAAGCTGGCCACTATCACATATGCTTACTCTTGCTTAAAATTAATAAATCA

>351_351_5_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000343687_BACE2_chr21_42598193_ENST00000330333_length(amino acids)=833AA_BP=419
MRISLPRAPERDGGVSASSLLDTVTNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSLPRRAAVNIEF
RDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLL
PHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLM
KGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMC
DSDHKRDLGGDAEVNPFLWHRPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSLQILVDTGSSNFAVAGTPHSYIDTYFDTERS
STYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIP
NVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKV
FDAVVEAVARASLIPEFSDGFWTGSQLACWTNSETPWSYFPKISIYLRDENSSRSFRITILPQLYIQPMMGAGLNYECYRFGISPSTNAL
VIGATVMEGFYVIFDRAQKRVGFAASPCAEIAGAAVSEISGPFSTEDVASNCVPAQSLSEPILWIVSYALMSVCGAILLVLIVLLLLPFR

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>351_351_6_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000343687_BACE2_chr21_42598193_ENST00000347667_length(transcript)=9397nt_BP=1408nt
AGCCTGCGACTGCACTCCCGGGGACACCCTCTCCCGGACCCACTCGGGGAGGCGGCGGCGAAGGCCCGGGGAGACCCGCGAGGGGCAAGC
CCGGATTCCTGCCGGCCGCCTTTCTGCGCGCGCCGGAGAGAGAGACGCGGTGGGGACAGGGATGCGCATTTCACTTCCCCGAGCTCCGGA
GAGGGATGGCGGGGTGTCGGCGAGTTCACTGCTGGACACAGTTACTAATGCCAGCAGTTACTCTGCAGAGATGACGGAGCCCAAGTCGGT
GTGTGTCTCGGTGGATGAGGTGGTGTCCAGCAACATGGAGGCCACTGAGACGGACCTGCTGAATGGACATCTGAAAAAAGTAGATAATAA
CCTCACGGAAGCCCAGCGCTTCTCCTCCTTGCCTCGGAGGGCAGCTGTGAACATTGAATTCAGGGACCTTTCCTATTCGGTTCCTGAAGG
ACCCTGGTGGAGGAAGAAAGGATACAAGACCCTCCTGAAAGGAATTTCCGGGAAGTTCAATAGTGGTGAGTTGGTGGCCATTATGGGTCC
TTCCGGGGCCGGGAAGTCCACGCTGATGAACATCCTGGCTGGATACAGGGAGACGGGCATGAAGGGGGCCGTCCTCATCAACGGCCTGCC
CCGGGACCTGCGCTGCTTCCGGAAGGTGTCCTGCTACATCATGCAGGATGACATGCTGCTGCCGCATCTCACTGTGCAGGAGGCCATGAT
GGTGTCGGCACATCTGAAGCTTCAGGAGAAGGATGAAGGCAGAAGGGAAATGGTCAAGGAGATACTGACAGCGCTGGGCTTGCTGTCTTG
CGCCAACACGCGGACCGGGAGCCTGTCAGGTGGTCAGCGCAAGCGCCTGGCCATCGCGCTGGAGCTGGTGAACAACCCTCCAGTCATGTT
CTTCGATGAGCCCACCAGCGGCCTGGACAGCGCCTCCTGCTTCCAGGTGGTCTCGCTGATGAAAGGGCTCGCTCAAGGGGGTCGCTCCAT
CATTTGCACCATCCACCAGCCCAGCGCCAAACTCTTCGAGCTGTTCGACCAGCTTTACGTCCTGAGTCAAGGACAATGTGTGTACCGGGG
AAAAGTCTGCAATCTTGTGCCATATTTGAGGGATTTGGGTCTGAACTGCCCAACCTACCACAACCCAGCAGATTTTGTCATGGAGGTTGC
ATCCGGCGAGTACGGTGATCAGAACAGTCGGCTGGTGAGAGCGGTTCGGGAGGGCATGTGTGACTCAGACCACAAGAGAGACCTCGGGGG
TGATGCCGAGGTGAACCCTTTTCTTTGGCACCGGCCCTCTGAAGAGGACTCCTCGTCCATGGAAGGCTGCCACAGCTTCTCTGCCAGCTG
CCTCACGCAGTTCTGCATCCTCTTCAAGAGGACCTTCCTCAGCATCATGAGGGACTCGCTACAGATTCTCGTTGACACTGGAAGCAGTAA
CTTTGCCGTGGCAGGAACCCCGCACTCCTACATAGACACGTACTTTGACACAGAGAGGTCTAGCACATACCGCTCCAAGGGCTTTGACGT
CACAGTGAAGTACACACAAGGAAGCTGGACGGGCTTCGTTGGGGAAGACCTCGTCACCATCCCCAAAGGCTTCAATACTTCTTTTCTTGT
CAACATTGCCACTATTTTTGAATCAGAGAATTTCTTTTTGCCTGGGATTAAATGGAATGGAATACTTGGCCTAGCTTATGCCACACTTGC
CAAGCCATCAAGTTCTCTGGAGACCTTCTTCGACTCCCTGGTGACACAAGCAAACATCCCCAACGTTTTCTCCATGCAGATGTGTGGAGC
CGGCTTGCCCGTTGCTGGATCTGGGACCAACGGAGGTAGTCTTGTCTTGGGTGGAATTGAACCAAGTTTGTATAAAGGAGACATCTGGTA
TACCCCTATTAAGGAAGAGTGGTACTACCAGATAGAAATTCTGAAATTGGAAATTGGAGGCCAAAGCCTTAATCTGGACTGCAGAGAGTA
TAACGCAGACAAGGCCATCGTGGACAGTGGCACCACGCTGCTGCGCCTGCCCCAGAAGGTGTTTGATGCGGTGGTGGAAGCTGTGGCCCG
CGCATCTCTGCTTTACATTCAGCCCATGATGGGGGCCGGCCTGAATTATGAATGTTACCGATTCGGCATTTCCCCATCCACAAATGCGCT
GGTGATCGGTGCCACGGTGATGGAGGGCTTCTACGTCATCTTCGACAGAGCCCAGAAGAGGGTGGGCTTCGCAGCGAGCCCCTGTGCAGA
AATTGCAGGTGCTGCAGTGTCTGAAATTTCCGGGCCTTTCTCAACAGAGGATGTAGCCAGCAACTGTGTCCCCGCTCAGTCTTTGAGCGA
GCCCATTTTGTGGATTGTGTCCTATGCGCTCATGAGCGTCTGTGGAGCCATCCTCCTTGTCTTAATCGTCCTGCTGCTGCTGCCGTTCCG
GTGTCAGCGTCGCCCCCGTGACCCTGAGGTCGTCAATGATGAGTCCTCTCTGGTCAGACATCGCTGGAAATGAATAGCCAGGCCTGACCT
CAAGCAACCATGAACTCAGCTATTAAGAAAATCACATTTCCAGGGCAGCAGCCGGGATCGATGGTGGCGCTTTCTCCTGTGCCCACCCGT
CTTCAATCTCTGTTCTGCTCCCAGATGCCTTCTAGATTCACTGTCTTTTGATTCTTGATTTTCAAGCTTTCAAATCCTCCCTACTTCCAA
GAAAAATAATTAAAAAAAAAACTTCATTCTAAACCAAAACAGAGTGGATTGGGCTGCAGGCTCTATGGGGTTCGTTATGCCAAAGTGTCT
ACATGTGCCACCAACATAAAACAAAACCAAGCCTTGGCTCGTTCTCTTCTCTCTTCAATCTCTGGAAAAATAAGTACATATAGTTGATAA
CCCCTCTTAGCTTACAGGAAGCTTTTTGTATTAATTGCCTTTGAGGTTATTTTCCGCCAGACCTCAACCTGGGTCAAAGTGGTACAGGAA
GGCTTGCAGTATGATGGCAGGAGAATCAGCCTGGGGCCTGGGGATGTAACCAAGCTGTACCCTTGAGACCTGGAACCAGAGCCACAGGCC
CCTTTTGTGGGTTTCTCTGTGCTCTGAATGGGAGCCAGAATTCACTAGGAGGTCATCAACCGATGGTCCTCACAAGCCTCTTCTGAAGAT
GGAAGGCCTTTTGCCCGTTGAGGTAGAGGGGAAGGAAATCTCCTCTTTTGTACCCAATACTTATGTTGTATTGTTGGTGCGAAAGTAAAA
ACACTACCTCTTTTGAGACTTTGCCCAGGGTCCTGTGCCTGGATGGGGGTGCAGGCAGCCTTGACCACGGCTGTTCCCCTCACCCAAAAG
AATTATCATCCCAACAGCCAAGACCCAACAGGTGCTGAACTGTGCATCAACCAGGAAGAGTTCTATCCCCAAGCTGGCCACTATCACATA
TGCTTACTCTTGCTTAAAATTAATAAATCATGTTTTGATGAGAAAAAACTATTCTATTTCACTAGCTTAGTTGTCTCTTTTTCCAAATCT
TCTCTGGAAGTAGGTTGGCTATTACCCTGTTGGGAAACAGGGAAATGGCCTGATGCCCCTATTTCTGACCAGCTGTCAGGGAAGGAAGAT
GCAAGATGTGCAGAAGACACAAGGTAACGTCTACTTATCCCCGTGCTTCGAAACCGTGTGTTTCCCTTTGCAGAACTGGTTAGCCTCAAG
CATACCCATCCAATCAGCTTAAATTGTTCAGCAGTTGACCTCTGTGCTTCTTCCTTTGGGGGTGTTTAATCTTTGGTAACAGTTGTGCAG
TGGTAGCCTTATTTCGGGGGGCAGTCCCTACTTTCTGTCACTTATCGAGGCCTTTGCCAAAGAAAAGTGGAAGCCGTTTCCTTGACATAG
CCTTATATGACCTGATGTCATTAGGAGAAGAGTTAAAAGACAGTATCCCCTCTCTCCTGCTTGTGTGCCAAGTTCAGTGTTCCCTTTGCA
TTTTTTTGGGGTGGGTTGGCTATATTACAGAATTCCACCAAAAGTGCTAAGTGTCCCCTCCTGCAGAAGTATCGTTTGTATTCACAGTAG
GCTACGTGTGGATGTTTCAGCCATCTGCTCTGCTCCCTGGGTCCCCGGGTCACCACCATACTGAGAAATATAGGACTCTGCCAAAGAGAC
GTGGAGGCCACGTCGGCTTGTCATGGTGTCCTGGAAGACTCTCCAGCAGCCAGAAGAACCTTCTGTGCTGTTTTCACTAGAGAAGATTTG
AGTTGCAGCCTCTTGGAAAGAACATGACGGCACGGAACGGGAGGAGGGGGCTCTTGTATCAGGGCCCGTTGTCACATCCGCTCTCAGCTT
GTTGAAAACTCATAATCTCAGAATGCATTTCACACGGAGAGATGTCTGGAAGTCCAATTCTCATCCCATTGGCTTTTTCCGTGGTTGCTG
TTTTGTGGGCCGCTTTGCACAGGAGTGAAGCCAACACCCCTAGATTGTGCCTTCACCCTTGCTGTGAAAAATTCAAAGCCCTGAAATAAG
AGGAGGGAATCGCAGACATGCCCTGATTAGTTTTCCTGCTTATTTCTTCATACAGGCATCTTCTGTTCCGTTGTATTGTGTTAGGTTTCA
GAGGCGGGGAGCTTCCTCCTGCAGCAGATGAACAGGCATAGTTCTTAAAATACAGGAAAGTAACAAGTGAGGTTTCCAGGTAGAGTAGGT
GAATGAAGTTTGCCGTCATGCTCTGTATTTCATATCAGATTTCTTTATCTTTTCATATCGCATGTCATTGGATGTGACATTTTGATGAAA
ATACTGAAACTACAAAAGCATAACTTCGCAACAAGAATGAGATAGACAATTGAATGTGGGACATTTTTCTGGCATGTCTTGCTGCTGAGA
ATCGGACTTCCAGTCAAAACCCTGTTAGTGACACCCACCTCCTCCAGTTATGCAAATTGATGCTTAGCTTGGCAAGCTTTCAAGGAGGTT
TGCTTGGAACAGGAAAGGAATTAACAACCCTTTGAGGGTGTCATTTTTACCTTGTAATACACTGTGGAAAATTCTGGAAGACGGTCCTTG
CCTGAAAAGGTGCAACTTAGCATTAGGTTGTTATCAGAAACCTTGTCAAGTCTGATGGGAAATGAATAGATGCTGCTTTATTTCCTTGAT
AACTTCTTTGGAAGTCTGAAATAAATCCTGCCTTCAGTAACTGAAACCATTTATTAAAAATAGCAAGAAACAAGATGGGGACCAATTCTA
TTTTTATTCTTGGGAATTTGAAAGAGCCACAAGTGATTGGTGTCCGATCTCCCAGCATATACTGTACACTATTTTGTATTTCTCCTGAAC
CAAAACCAAGTACTTAGCACTCAAGAAACAGATGCCCTGTGTGTGACCGAGGGGAGTGTTTTTCCACAACAGGTTCCACTTCTGAACACT
TGGAAGGACCTTGCCTGATTCATGGTGAAACACAGAGGTTTTGGTTGGAGATAAATTTGGGGTCAGTTACTGTTCAAAATTGTGAAAGTA
GTTCCCAGGAAGACAGCATTAGTGACTCCGCAGTGCTTTGGGTAATAGATTTTGAAAAGCAATTGTGAGTTGGGGATTCCATCATTTCAT
TTAAGAGGTGAAGAGGGATTTAATTATTTAATACGCCGGGTGCAAACTTGTTAAATTCCTCTTTCCCTGTCCCTGCTTGGTGGAGCTGCC
ACGTGTGGTTCAGTTCTAAGTTCTGGACTAGTGCCACTCGATATCATTGGGAATAAATCGTTGTTCAACAGTCTGTTCCACAAACAACAG
TAATTGAATTTCACAGACTTTATCCTGATTAGTGGAAATCAAATAATGGAGTGGAATCCCCATGTGTTTTCTCTTGCACAAACTTATTAG
ACTTGATTAGAAAACTGTTTGGAGGAAAAACTTGCCAGTAAGTTTTTTGGTTGTTGTTTTGTTTTTTTTGAAAAACGACGCAACACCATA
AAGTGTAAAATTAGGGGTTCTGGCCAAGAGAGGTACTAGATTTTTTTAATGCCGAGAAAAGTCCATGCCACAGAAGTTATTGTGTATGTC
TCTAGGGAGCTTTAAGAATTTCACGTTTGAACTTTACAGCTGTTTACCAATTAAATGGCAAGCTGGAAAAATACATTTTGAGAGGGGTAG
AAAGAATAAGAATATAATTAAAAGTATGCTAACAAAATAAGCAGTACATATTTTTTTAGAAAATGCAGTTTAGGCCAGGCACGGTAGCTC
GTGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGGACAACATGGTGAAAC
CCCGTCTCTACTAAAAATACAAAAAATTAGCCAACGATGGTGATGCCTGTCTGTAATCCCAGCTACTCTGGAGGCTGAGGCAGGAGAATC
GCTTGAACCGGGGAGGCAGAGGTTGTAGTGAGCCAAGATTGCGCCACTGCACTCCAGCCTGGGCAACAGAGCAAGACTCCGTCTCAAAAA
AGGAAAGAAAATGCAGTTTCATTCCAGCCATCCTTAGATTTCTTTTCCCCTTAAAGTGGCTGAATCCATTGGAGATGTGATTTATTTTGC
AGATCCACCAATTCCAAACTTCAGGAATATTCAAGCGGGAGTCATGTGTAAGTGACAGCTTTGACAAAGAGAGACTGTGGCTGGGTGGCC
CGGGTGTTGCCCACGCGGAGCAAGGATTGGTTCATTCAACGGATGGAGAGTACAGGATGGCTGGGACCTGGGAAGTTCCAGAATCTGAAA
AGAGGGCAGGGCAAGAAGGAGCCAGAAGAGAGGTCCCACCCCTCAGTTGGCAGTGGGGCACGGAGGTCCGCATCAGCCAAGAACGTCCCC
AGGATGCCGTGGGCACCTCATTTCACCCCACGTTTTTGGCACAGTCTACTTTTTAGGTATTTTGTAAAGGAACTTCTCAGGATTGATTAT
TTGCCAGAGGAACAATTAGGCCAAGAGAAACTTGCTTGACAGCCATGTGTAAAACACGTCTGTCCTAATCAAACTAGAGATGCCTCAAGG
CCCACGCAGGACACAGGCAGGTTCAAGGTCATGCACCTGGAAATTTGTAGGGGAGGGTCAAGCAACTGAGGCCAAAGGGGGCCGGTAAAG
TGGCTTCTGGGGTCTGAGCATCTGGAAGGCTCCTGGCAGCAGTTACCTGACAGTGTCGTTGAGGGGCACGGCAGCTGGGCCCTCACCGTT
TCCGCCAGCTCTGCTGAGCCAGCCCAGCCCATGCATTCCGAACATCCGACAGCTTCTTTCTCCAGAATGTCTTCTGTCAGAGACTTCCAG
GAAAGGAGCTCCCTCCTGTCTCACTGCTGTCAGCGTGGGAGCCCTGCTCCCCAGGCTCCACGTCCCCGGAAGGTCCATCTTGTCCTGGAG
CACACCCAGCCCCATTCAGGGTCAGTGCAGGAGGGAACAGGGAATCTGCATTTCAGTAAGCTCCCCAGGTGAGGCTGCAGAGCAGAAACC
ACGGCTTTCAGACGTGAGCAGGCTCCCTGGGCTCTTGGTGTCACCCTGTTAGCCACATCTGCGGAATGTGGAAGGCAGAACATAGCCACG
CTGCTTAGTGCTGCCAGCGAACCTCAGGTTGCATCAGTGGCTGGAATCTATCACAGCTGTTGGGGATACGTAACTCCCAGCAATAAATCC
AGTATTTTCTTCCCTGCCCTGAGCTTCCTCTGGGTTTCTTATCAGCAGCTATTACACACAGATGTCCAGTGCTTCTAAACTAAATTGTAC
TGTGTAACTTTTACATCACACTTGTGTGCTTAAAAAGCACACCGTGGGTAGTGACTGGGCCAAGAGACATCACAAAGCTTCCTGATAAAT
TTGAATCCAGCCACGGCAAGAGCGACGTGCGGGTACCTGGTCCCTGATGCTTGGGTGCCCCGTTGAGCCTCGGGTACTTCTTGGACACTA
TTGTGAGAGCAGCCATCCTGGTGTCTCTGCCAGCATCTTGGGGAACGCTGTGATGGTAAAATATCTGTCTCTCCTCTGGGAATCAGGGCA
GCCCTGAGAAGTGAGCAGTTCCCTTTACAGATGGATAATTGTTTGTGTAAGACCAACCAGATAAAGTCCAAACTGTGTAGAACACACGTG
TGCCTCACACATAGCCATCTGAGTAAAATATTTTTTCCAATGTAGATTTATAATTAGAAATGACAGATTTATAATATAGACTTCAGTAAG
TTGGGCACAGCTGTCACTTTCGTGGTATCAATAAAAGGCTAGAAACCTTGGGTGTCCTTGGCAACCTAGCCTTTGACATTGATGTTTTTC
CATAGGATTTTCTTCATTTGGGTTGGAATAAAAATGCATTTTTATTCACAAGGCACAGACAGATAAGAATATCATAAGCAGGGAAGTGTC
TCCAAAGGTCAGGACATATGTTTTTCTGTTGAGTGCTATATGTGGAGGTCATTGCAAGTTCCCTGATATGAGTATGGTTTCGCTTGCTAC
ATTGTGCCTATTAAAGTAAAATTTTACACAAGCCTCGCATTTCTAAGATTAGTGTTCCTGAATGAAATGTTAAGAAAACATTAAAAGATT
ATCTCTTTTTAAGATGGAGGAAAAAAAGTGAACAAAGCTAATTAATCTATCATGAAAATTGCACAAAATAACATTTCTTAACAAATTTAA
TACAATTTTGTGTTCTTTGTTGCTAGTGGTATAAAACGAGATTTTTTTCCCTCATTTTTCTCATTGTAGATGTCATCTCTCACATTTATA
TCAGTGAGGTTTGAAATTCTGTGTAGCAGTTACTCAGCACATATGAGAGGGCAGCGAATGAATGAGATTTGTCATGTGCTAATAAAAGCT
GAATTTTTGTAATCTAAAATGATGTATTTTCTACTATTGCTGTTAATTTGCATTGTTAAAAATTCTTAAAGTTTAATATGTTATGTTCAG
TCATTGAAAGCGACCACTCATTTTTTTCTTAAAGTTGATGCCTTTTCTGCTGTGCTAGAGTCAGTATTTTGCTTCTGGCAGGAGAGCTGC
AAACTGTGTATCCTCAAACAGATGCAAAAAGTAGTGCTTTGCAAAACGTTTGTTTTCTGTTTATCTCAGATTAACATCCTTTAATACAAG
TTTCTTAAGTGTAACTTGTATTTCTGAAAATGCTTAAAATTATTTTATATTTCCCTTTGGGAATTTTTCTCTATTTCCAGCACGCTGATT
TGATTTAAAAATGTAATAAGACCAAGAGTTGGAGTAAAGGGATATTCATTCCATGTTAAAAGTGGCTTCATAGCTACTGACAAATGTCTG
AACTATTGTCGTGCCCTTCAAAACTGGAGTTTTCTAAAATAATCTTATTTTTATACTTGTATGTTCCAGCAATTTAAGATATATACCATT

>351_351_6_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000343687_BACE2_chr21_42598193_ENST00000347667_length(amino acids)=783AA_BP=419
MRISLPRAPERDGGVSASSLLDTVTNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSLPRRAAVNIEF
RDLSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLL
PHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLM
KGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMC
DSDHKRDLGGDAEVNPFLWHRPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSLQILVDTGSSNFAVAGTPHSYIDTYFDTERS
STYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIP
NVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKV
FDAVVEAVARASLLYIQPMMGAGLNYECYRFGISPSTNALVIGATVMEGFYVIFDRAQKRVGFAASPCAEIAGAAVSEISGPFSTEDVAS

--------------------------------------------------------------
>351_351_7_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000347800_BACE2_chr21_42598193_ENST00000328735_length(transcript)=3343nt_BP=1294nt
GCTTTATAAAGGGGAGTTTCCCTGCACAAGCTCTCTCTCTTGTCTGCCGCCATGTGAGACATGCCTTTCACCTTCCGCCATGATCATGAG
GCTTCCCCAGCCACATGGAACTAATGCCAGCAGTTACTCTGCAGAGATGACGGAGCCCAAGTCGGTGTGTGTCTCGGTGGATGAGGTGGT
GTCCAGCAACATGGAGGCCACTGAGACGGACCTGCTGAATGGACATCTGAAAAAAGTAGATAATAACCTCACGGAAGCCCAGCGCTTCTC
CTCCTTGCCTCGGAGGGCAGCTGTGAACATTGAATTCAGGGACCTTTCCTATTCGGTTCCTGAAGGACCCTGGTGGAGGAAGAAAGGATA
CAAGACCCTCCTGAAAGGAATTTCCGGGAAGTTCAATAGTGGTGAGTTGGTGGCCATTATGGGTCCTTCCGGGGCCGGGAAGTCCACGCT
GATGAACATCCTGGCTGGATACAGGGAGACGGGCATGAAGGGGGCCGTCCTCATCAACGGCCTGCCCCGGGACCTGCGCTGCTTCCGGAA
GGTGTCCTGCTACATCATGCAGGATGACATGCTGCTGCCGCATCTCACTGTGCAGGAGGCCATGATGGTGTCGGCACATCTGAAGCTTCA
GGAGAAGGATGAAGGCAGAAGGGAAATGGTCAAGGAGATACTGACAGCGCTGGGCTTGCTGTCTTGCGCCAACACGCGGACCGGGAGCCT
GTCAGGTGGTCAGCGCAAGCGCCTGGCCATCGCGCTGGAGCTGGTGAACAACCCTCCAGTCATGTTCTTCGATGAGCCCACCAGCGGCCT
GGACAGCGCCTCCTGCTTCCAGGTGGTCTCGCTGATGAAAGGGCTCGCTCAAGGGGGTCGCTCCATCATTTGCACCATCCACCAGCCCAG
CGCCAAACTCTTCGAGCTGTTCGACCAGCTTTACGTCCTGAGTCAAGGACAATGTGTGTACCGGGGAAAAGTCTGCAATCTTGTGCCATA
TTTGAGGGATTTGGGTCTGAACTGCCCAACCTACCACAACCCAGCAGATTTTGTCATGGAGGTTGCATCCGGCGAGTACGGTGATCAGAA
CAGTCGGCTGGTGAGAGCGGTTCGGGAGGGCATGTGTGACTCAGACCACAAGAGAGACCTCGGGGGTGATGCCGAGGTGAACCCTTTTCT
TTGGCACCGGCCCTCTGAAGAGGACTCCTCGTCCATGGAAGGCTGCCACAGCTTCTCTGCCAGCTGCCTCACGCAGTTCTGCATCCTCTT
CAAGAGGACCTTCCTCAGCATCATGAGGGACTCGCTACAGATTCTCGTTGACACTGGAAGCAGTAACTTTGCCGTGGCAGGAACCCCGCA
CTCCTACATAGACACGTACTTTGACACAGAGAGGTCTAGCACATACCGCTCCAAGGGCTTTGACGTCACAGTGAAGTACACACAAGGAAG
CTGGACGGGCTTCGTTGGGGAAGACCTCGTCACCATCCCCAAAGGCTTCAATACTTCTTTTCTTGTCAACATTGCCACTATTTTTGAATC
AGAGAATTTCTTTTTGCCTGGGATTAAATGGAATGGAATACTTGGCCTAGCTTATGCCACACTTGCCAAGCCATCAAGTTCTCTGGAGAC
CTTCTTCGACTCCCTGGTGACACAAGCAAACATCCCCAACGTTTTCTCCATGCAGATGTGTGGAGCCGGCTTGCCCGTTGCTGGATCTGG
GACCAACGGAGGTAGTCTTGTCTTGGGTGGAATTGAACCAAGTTTGTATAAAGGAGACATCTGGTATACCCCTATTAAGGAAGAGTGGTA
CTACCAGATAGAAATTCTGAAATTGGAAATTGGAGGCCAAAGCCTTAATCTGGACTGCAGAGAGTATAACGCAGACAAGGCCATCGTGGA
CAGTGGCACCACGCTGCTGCGCCTGCCCCAGAAGGTGTTTGATGCGGTGGTGGAAGCTGTGGCCCGCGCATCTCTGATTCCAGAATTCTC
TGATGGTTTCTGGACTGGGTCCCAGCTGGCGTGCTGGACGAATTCGGAAACACCTTGGTCTTACTTCCCTAAAATCTCCATCTACCTGAG
AGACGAGAACTCCAGCAGGTCATTCCGTATCACAATCCTGCCTCAGAAATTGCAGGTGCTGCAGTGTCTGAAATTTCCGGGCCTTTCTCA
ACAGAGGATGTAGCCAGCAACTGTGTCCCCGCTCAGTCTTTGAGCGAGCCCATTTTGTGGATTGTGTCCTATGCGCTCATGAGCGTCTGT
GGAGCCATCCTCCTTGTCTTAATCGTCCTGCTGCTGCTGCCGTTCCGGTGTCAGCGTCGCCCCCGTGACCCTGAGGTCGTCAATGATGAG
TCCTCTCTGGTCAGACATCGCTGGAAATGAATAGCCAGGCCTGACCTCAAGCAACCATGAACTCAGCTATTAAGAAAATCACATTTCCAG
GGCAGCAGCCGGGATCGATGGTGGCGCTTTCTCCTGTGCCCACCCGTCTTCAATCTCTGTTCTGCTCCCAGATGCCTTCTAGATTCACTG
TCTTTTGATTCTTGATTTTCAAGCTTTCAAATCCTCCCTACTTCCAAGAAAAATAATTAAAAAAAAAACTTCATTCTAAACCAAAACAGA
GTGGATTGGGCTGCAGGCTCTATGGGGTTCGTTATGCCAAAGTGTCTACATGTGCCACCAACATAAAACAAAACCAAGCCTTGGCTCGTT
CTCTTCTCTCTTCAATCTCTGGAAAAATAAGTACATATAGTTGATAACCCCTCTTAGCTTACAGGAAGCTTTTTGTATTAATTGCCTTTG
AGGTTATTTTCCGCCAGACCTCAACCTGGGTCAAAGTGGTACAGGAAGGCTTGCAGTATGATGGCAGGAGAATCAGCCTGGGGCCTGGGG
ATGTAACCAAGCTGTACCCTTGAGACCTGGAACCAGAGCCACAGGCCCCTTTTGTGGGTTTCTCTGTGCTCTGAATGGGAGCCAGAATTC
ACTAGGAGGTCATCAACCGATGGTCCTCACAAGCCTCTTCTGAAGATGGAAGGCCTTTTGCCCGTTGAGGTAGAGGGGAAGGAAATCTCC
TCTTTTGTACCCAATACTTATGTTGTATTGTTGGTGCGAAAGTAAAAACACTACCTCTTTTGAGACTTTGCCCAGGGTCCTGTGCCTGGA
TGGGGGTGCAGGCAGCCTTGACCACGGCTGTTCCCCTCACCCAAAAGAATTATCATCCCAACAGCCAAGACCCAACAGGTGCTGAACTGT
GCATCAACCAGGAAGAGTTCTATCCCCAAGCTGGCCACTATCACATATGCTTACTCTTGCTTAAAATTAATAAATCATGTTTTGATGAGA

>351_351_7_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000347800_BACE2_chr21_42598193_ENST00000328735_length(amino acids)=709AA_BP=2
MPPCETCLSPSAMIMRLPQPHGTNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSLPRRAAVNIEFRD
LSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPH
LTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKG
LAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDS
DHKRDLGGDAEVNPFLWHRPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSLQILVDTGSSNFAVAGTPHSYIDTYFDTERSST
YRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNV
FSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFD

--------------------------------------------------------------
>351_351_8_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000347800_BACE2_chr21_42598193_ENST00000330333_length(transcript)=3512nt_BP=1294nt
GCTTTATAAAGGGGAGTTTCCCTGCACAAGCTCTCTCTCTTGTCTGCCGCCATGTGAGACATGCCTTTCACCTTCCGCCATGATCATGAG
GCTTCCCCAGCCACATGGAACTAATGCCAGCAGTTACTCTGCAGAGATGACGGAGCCCAAGTCGGTGTGTGTCTCGGTGGATGAGGTGGT
GTCCAGCAACATGGAGGCCACTGAGACGGACCTGCTGAATGGACATCTGAAAAAAGTAGATAATAACCTCACGGAAGCCCAGCGCTTCTC
CTCCTTGCCTCGGAGGGCAGCTGTGAACATTGAATTCAGGGACCTTTCCTATTCGGTTCCTGAAGGACCCTGGTGGAGGAAGAAAGGATA
CAAGACCCTCCTGAAAGGAATTTCCGGGAAGTTCAATAGTGGTGAGTTGGTGGCCATTATGGGTCCTTCCGGGGCCGGGAAGTCCACGCT
GATGAACATCCTGGCTGGATACAGGGAGACGGGCATGAAGGGGGCCGTCCTCATCAACGGCCTGCCCCGGGACCTGCGCTGCTTCCGGAA
GGTGTCCTGCTACATCATGCAGGATGACATGCTGCTGCCGCATCTCACTGTGCAGGAGGCCATGATGGTGTCGGCACATCTGAAGCTTCA
GGAGAAGGATGAAGGCAGAAGGGAAATGGTCAAGGAGATACTGACAGCGCTGGGCTTGCTGTCTTGCGCCAACACGCGGACCGGGAGCCT
GTCAGGTGGTCAGCGCAAGCGCCTGGCCATCGCGCTGGAGCTGGTGAACAACCCTCCAGTCATGTTCTTCGATGAGCCCACCAGCGGCCT
GGACAGCGCCTCCTGCTTCCAGGTGGTCTCGCTGATGAAAGGGCTCGCTCAAGGGGGTCGCTCCATCATTTGCACCATCCACCAGCCCAG
CGCCAAACTCTTCGAGCTGTTCGACCAGCTTTACGTCCTGAGTCAAGGACAATGTGTGTACCGGGGAAAAGTCTGCAATCTTGTGCCATA
TTTGAGGGATTTGGGTCTGAACTGCCCAACCTACCACAACCCAGCAGATTTTGTCATGGAGGTTGCATCCGGCGAGTACGGTGATCAGAA
CAGTCGGCTGGTGAGAGCGGTTCGGGAGGGCATGTGTGACTCAGACCACAAGAGAGACCTCGGGGGTGATGCCGAGGTGAACCCTTTTCT
TTGGCACCGGCCCTCTGAAGAGGACTCCTCGTCCATGGAAGGCTGCCACAGCTTCTCTGCCAGCTGCCTCACGCAGTTCTGCATCCTCTT
CAAGAGGACCTTCCTCAGCATCATGAGGGACTCGCTACAGATTCTCGTTGACACTGGAAGCAGTAACTTTGCCGTGGCAGGAACCCCGCA
CTCCTACATAGACACGTACTTTGACACAGAGAGGTCTAGCACATACCGCTCCAAGGGCTTTGACGTCACAGTGAAGTACACACAAGGAAG
CTGGACGGGCTTCGTTGGGGAAGACCTCGTCACCATCCCCAAAGGCTTCAATACTTCTTTTCTTGTCAACATTGCCACTATTTTTGAATC
AGAGAATTTCTTTTTGCCTGGGATTAAATGGAATGGAATACTTGGCCTAGCTTATGCCACACTTGCCAAGCCATCAAGTTCTCTGGAGAC
CTTCTTCGACTCCCTGGTGACACAAGCAAACATCCCCAACGTTTTCTCCATGCAGATGTGTGGAGCCGGCTTGCCCGTTGCTGGATCTGG
GACCAACGGAGGTAGTCTTGTCTTGGGTGGAATTGAACCAAGTTTGTATAAAGGAGACATCTGGTATACCCCTATTAAGGAAGAGTGGTA
CTACCAGATAGAAATTCTGAAATTGGAAATTGGAGGCCAAAGCCTTAATCTGGACTGCAGAGAGTATAACGCAGACAAGGCCATCGTGGA
CAGTGGCACCACGCTGCTGCGCCTGCCCCAGAAGGTGTTTGATGCGGTGGTGGAAGCTGTGGCCCGCGCATCTCTGATTCCAGAATTCTC
TGATGGTTTCTGGACTGGGTCCCAGCTGGCGTGCTGGACGAATTCGGAAACACCTTGGTCTTACTTCCCTAAAATCTCCATCTACCTGAG
AGACGAGAACTCCAGCAGGTCATTCCGTATCACAATCCTGCCTCAGCTTTACATTCAGCCCATGATGGGGGCCGGCCTGAATTATGAATG
TTACCGATTCGGCATTTCCCCATCCACAAATGCGCTGGTGATCGGTGCCACGGTGATGGAGGGCTTCTACGTCATCTTCGACAGAGCCCA
GAAGAGGGTGGGCTTCGCAGCGAGCCCCTGTGCAGAAATTGCAGGTGCTGCAGTGTCTGAAATTTCCGGGCCTTTCTCAACAGAGGATGT
AGCCAGCAACTGTGTCCCCGCTCAGTCTTTGAGCGAGCCCATTTTGTGGATTGTGTCCTATGCGCTCATGAGCGTCTGTGGAGCCATCCT
CCTTGTCTTAATCGTCCTGCTGCTGCTGCCGTTCCGGTGTCAGCGTCGCCCCCGTGACCCTGAGGTCGTCAATGATGAGTCCTCTCTGGT
CAGACATCGCTGGAAATGAATAGCCAGGCCTGACCTCAAGCAACCATGAACTCAGCTATTAAGAAAATCACATTTCCAGGGCAGCAGCCG
GGATCGATGGTGGCGCTTTCTCCTGTGCCCACCCGTCTTCAATCTCTGTTCTGCTCCCAGATGCCTTCTAGATTCACTGTCTTTTGATTC
TTGATTTTCAAGCTTTCAAATCCTCCCTACTTCCAAGAAAAATAATTAAAAAAAAAACTTCATTCTAAACCAAAACAGAGTGGATTGGGC
TGCAGGCTCTATGGGGTTCGTTATGCCAAAGTGTCTACATGTGCCACCAACATAAAACAAAACCAAGCCTTGGCTCGTTCTCTTCTCTCT
TCAATCTCTGGAAAAATAAGTACATATAGTTGATAACCCCTCTTAGCTTACAGGAAGCTTTTTGTATTAATTGCCTTTGAGGTTATTTTC
CGCCAGACCTCAACCTGGGTCAAAGTGGTACAGGAAGGCTTGCAGTATGATGGCAGGAGAATCAGCCTGGGGCCTGGGGATGTAACCAAG
CTGTACCCTTGAGACCTGGAACCAGAGCCACAGGCCCCTTTTGTGGGTTTCTCTGTGCTCTGAATGGGAGCCAGAATTCACTAGGAGGTC
ATCAACCGATGGTCCTCACAAGCCTCTTCTGAAGATGGAAGGCCTTTTGCCCGTTGAGGTAGAGGGGAAGGAAATCTCCTCTTTTGTACC
CAATACTTATGTTGTATTGTTGGTGCGAAAGTAAAAACACTACCTCTTTTGAGACTTTGCCCAGGGTCCTGTGCCTGGATGGGGGTGCAG
GCAGCCTTGACCACGGCTGTTCCCCTCACCCAAAAGAATTATCATCCCAACAGCCAAGACCCAACAGGTGCTGAACTGTGCATCAACCAG
GAAGAGTTCTATCCCCAAGCTGGCCACTATCACATATGCTTACTCTTGCTTAAAATTAATAAATCATGTTTTGATGAGAAAAAACTATTC

>351_351_8_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000347800_BACE2_chr21_42598193_ENST00000330333_length(amino acids)=831AA_BP=2
MPPCETCLSPSAMIMRLPQPHGTNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSLPRRAAVNIEFRD
LSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPH
LTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKG
LAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDS
DHKRDLGGDAEVNPFLWHRPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSLQILVDTGSSNFAVAGTPHSYIDTYFDTERSST
YRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNV
FSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFD
AVVEAVARASLIPEFSDGFWTGSQLACWTNSETPWSYFPKISIYLRDENSSRSFRITILPQLYIQPMMGAGLNYECYRFGISPSTNALVI
GATVMEGFYVIFDRAQKRVGFAASPCAEIAGAAVSEISGPFSTEDVASNCVPAQSLSEPILWIVSYALMSVCGAILLVLIVLLLLPFRCQ

--------------------------------------------------------------
>351_351_9_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000347800_BACE2_chr21_42598193_ENST00000347667_length(transcript)=9283nt_BP=1294nt
GCTTTATAAAGGGGAGTTTCCCTGCACAAGCTCTCTCTCTTGTCTGCCGCCATGTGAGACATGCCTTTCACCTTCCGCCATGATCATGAG
GCTTCCCCAGCCACATGGAACTAATGCCAGCAGTTACTCTGCAGAGATGACGGAGCCCAAGTCGGTGTGTGTCTCGGTGGATGAGGTGGT
GTCCAGCAACATGGAGGCCACTGAGACGGACCTGCTGAATGGACATCTGAAAAAAGTAGATAATAACCTCACGGAAGCCCAGCGCTTCTC
CTCCTTGCCTCGGAGGGCAGCTGTGAACATTGAATTCAGGGACCTTTCCTATTCGGTTCCTGAAGGACCCTGGTGGAGGAAGAAAGGATA
CAAGACCCTCCTGAAAGGAATTTCCGGGAAGTTCAATAGTGGTGAGTTGGTGGCCATTATGGGTCCTTCCGGGGCCGGGAAGTCCACGCT
GATGAACATCCTGGCTGGATACAGGGAGACGGGCATGAAGGGGGCCGTCCTCATCAACGGCCTGCCCCGGGACCTGCGCTGCTTCCGGAA
GGTGTCCTGCTACATCATGCAGGATGACATGCTGCTGCCGCATCTCACTGTGCAGGAGGCCATGATGGTGTCGGCACATCTGAAGCTTCA
GGAGAAGGATGAAGGCAGAAGGGAAATGGTCAAGGAGATACTGACAGCGCTGGGCTTGCTGTCTTGCGCCAACACGCGGACCGGGAGCCT
GTCAGGTGGTCAGCGCAAGCGCCTGGCCATCGCGCTGGAGCTGGTGAACAACCCTCCAGTCATGTTCTTCGATGAGCCCACCAGCGGCCT
GGACAGCGCCTCCTGCTTCCAGGTGGTCTCGCTGATGAAAGGGCTCGCTCAAGGGGGTCGCTCCATCATTTGCACCATCCACCAGCCCAG
CGCCAAACTCTTCGAGCTGTTCGACCAGCTTTACGTCCTGAGTCAAGGACAATGTGTGTACCGGGGAAAAGTCTGCAATCTTGTGCCATA
TTTGAGGGATTTGGGTCTGAACTGCCCAACCTACCACAACCCAGCAGATTTTGTCATGGAGGTTGCATCCGGCGAGTACGGTGATCAGAA
CAGTCGGCTGGTGAGAGCGGTTCGGGAGGGCATGTGTGACTCAGACCACAAGAGAGACCTCGGGGGTGATGCCGAGGTGAACCCTTTTCT
TTGGCACCGGCCCTCTGAAGAGGACTCCTCGTCCATGGAAGGCTGCCACAGCTTCTCTGCCAGCTGCCTCACGCAGTTCTGCATCCTCTT
CAAGAGGACCTTCCTCAGCATCATGAGGGACTCGCTACAGATTCTCGTTGACACTGGAAGCAGTAACTTTGCCGTGGCAGGAACCCCGCA
CTCCTACATAGACACGTACTTTGACACAGAGAGGTCTAGCACATACCGCTCCAAGGGCTTTGACGTCACAGTGAAGTACACACAAGGAAG
CTGGACGGGCTTCGTTGGGGAAGACCTCGTCACCATCCCCAAAGGCTTCAATACTTCTTTTCTTGTCAACATTGCCACTATTTTTGAATC
AGAGAATTTCTTTTTGCCTGGGATTAAATGGAATGGAATACTTGGCCTAGCTTATGCCACACTTGCCAAGCCATCAAGTTCTCTGGAGAC
CTTCTTCGACTCCCTGGTGACACAAGCAAACATCCCCAACGTTTTCTCCATGCAGATGTGTGGAGCCGGCTTGCCCGTTGCTGGATCTGG
GACCAACGGAGGTAGTCTTGTCTTGGGTGGAATTGAACCAAGTTTGTATAAAGGAGACATCTGGTATACCCCTATTAAGGAAGAGTGGTA
CTACCAGATAGAAATTCTGAAATTGGAAATTGGAGGCCAAAGCCTTAATCTGGACTGCAGAGAGTATAACGCAGACAAGGCCATCGTGGA
CAGTGGCACCACGCTGCTGCGCCTGCCCCAGAAGGTGTTTGATGCGGTGGTGGAAGCTGTGGCCCGCGCATCTCTGCTTTACATTCAGCC
CATGATGGGGGCCGGCCTGAATTATGAATGTTACCGATTCGGCATTTCCCCATCCACAAATGCGCTGGTGATCGGTGCCACGGTGATGGA
GGGCTTCTACGTCATCTTCGACAGAGCCCAGAAGAGGGTGGGCTTCGCAGCGAGCCCCTGTGCAGAAATTGCAGGTGCTGCAGTGTCTGA
AATTTCCGGGCCTTTCTCAACAGAGGATGTAGCCAGCAACTGTGTCCCCGCTCAGTCTTTGAGCGAGCCCATTTTGTGGATTGTGTCCTA
TGCGCTCATGAGCGTCTGTGGAGCCATCCTCCTTGTCTTAATCGTCCTGCTGCTGCTGCCGTTCCGGTGTCAGCGTCGCCCCCGTGACCC
TGAGGTCGTCAATGATGAGTCCTCTCTGGTCAGACATCGCTGGAAATGAATAGCCAGGCCTGACCTCAAGCAACCATGAACTCAGCTATT
AAGAAAATCACATTTCCAGGGCAGCAGCCGGGATCGATGGTGGCGCTTTCTCCTGTGCCCACCCGTCTTCAATCTCTGTTCTGCTCCCAG
ATGCCTTCTAGATTCACTGTCTTTTGATTCTTGATTTTCAAGCTTTCAAATCCTCCCTACTTCCAAGAAAAATAATTAAAAAAAAAACTT
CATTCTAAACCAAAACAGAGTGGATTGGGCTGCAGGCTCTATGGGGTTCGTTATGCCAAAGTGTCTACATGTGCCACCAACATAAAACAA
AACCAAGCCTTGGCTCGTTCTCTTCTCTCTTCAATCTCTGGAAAAATAAGTACATATAGTTGATAACCCCTCTTAGCTTACAGGAAGCTT
TTTGTATTAATTGCCTTTGAGGTTATTTTCCGCCAGACCTCAACCTGGGTCAAAGTGGTACAGGAAGGCTTGCAGTATGATGGCAGGAGA
ATCAGCCTGGGGCCTGGGGATGTAACCAAGCTGTACCCTTGAGACCTGGAACCAGAGCCACAGGCCCCTTTTGTGGGTTTCTCTGTGCTC
TGAATGGGAGCCAGAATTCACTAGGAGGTCATCAACCGATGGTCCTCACAAGCCTCTTCTGAAGATGGAAGGCCTTTTGCCCGTTGAGGT
AGAGGGGAAGGAAATCTCCTCTTTTGTACCCAATACTTATGTTGTATTGTTGGTGCGAAAGTAAAAACACTACCTCTTTTGAGACTTTGC
CCAGGGTCCTGTGCCTGGATGGGGGTGCAGGCAGCCTTGACCACGGCTGTTCCCCTCACCCAAAAGAATTATCATCCCAACAGCCAAGAC
CCAACAGGTGCTGAACTGTGCATCAACCAGGAAGAGTTCTATCCCCAAGCTGGCCACTATCACATATGCTTACTCTTGCTTAAAATTAAT
AAATCATGTTTTGATGAGAAAAAACTATTCTATTTCACTAGCTTAGTTGTCTCTTTTTCCAAATCTTCTCTGGAAGTAGGTTGGCTATTA
CCCTGTTGGGAAACAGGGAAATGGCCTGATGCCCCTATTTCTGACCAGCTGTCAGGGAAGGAAGATGCAAGATGTGCAGAAGACACAAGG
TAACGTCTACTTATCCCCGTGCTTCGAAACCGTGTGTTTCCCTTTGCAGAACTGGTTAGCCTCAAGCATACCCATCCAATCAGCTTAAAT
TGTTCAGCAGTTGACCTCTGTGCTTCTTCCTTTGGGGGTGTTTAATCTTTGGTAACAGTTGTGCAGTGGTAGCCTTATTTCGGGGGGCAG
TCCCTACTTTCTGTCACTTATCGAGGCCTTTGCCAAAGAAAAGTGGAAGCCGTTTCCTTGACATAGCCTTATATGACCTGATGTCATTAG
GAGAAGAGTTAAAAGACAGTATCCCCTCTCTCCTGCTTGTGTGCCAAGTTCAGTGTTCCCTTTGCATTTTTTTGGGGTGGGTTGGCTATA
TTACAGAATTCCACCAAAAGTGCTAAGTGTCCCCTCCTGCAGAAGTATCGTTTGTATTCACAGTAGGCTACGTGTGGATGTTTCAGCCAT
CTGCTCTGCTCCCTGGGTCCCCGGGTCACCACCATACTGAGAAATATAGGACTCTGCCAAAGAGACGTGGAGGCCACGTCGGCTTGTCAT
GGTGTCCTGGAAGACTCTCCAGCAGCCAGAAGAACCTTCTGTGCTGTTTTCACTAGAGAAGATTTGAGTTGCAGCCTCTTGGAAAGAACA
TGACGGCACGGAACGGGAGGAGGGGGCTCTTGTATCAGGGCCCGTTGTCACATCCGCTCTCAGCTTGTTGAAAACTCATAATCTCAGAAT
GCATTTCACACGGAGAGATGTCTGGAAGTCCAATTCTCATCCCATTGGCTTTTTCCGTGGTTGCTGTTTTGTGGGCCGCTTTGCACAGGA
GTGAAGCCAACACCCCTAGATTGTGCCTTCACCCTTGCTGTGAAAAATTCAAAGCCCTGAAATAAGAGGAGGGAATCGCAGACATGCCCT
GATTAGTTTTCCTGCTTATTTCTTCATACAGGCATCTTCTGTTCCGTTGTATTGTGTTAGGTTTCAGAGGCGGGGAGCTTCCTCCTGCAG
CAGATGAACAGGCATAGTTCTTAAAATACAGGAAAGTAACAAGTGAGGTTTCCAGGTAGAGTAGGTGAATGAAGTTTGCCGTCATGCTCT
GTATTTCATATCAGATTTCTTTATCTTTTCATATCGCATGTCATTGGATGTGACATTTTGATGAAAATACTGAAACTACAAAAGCATAAC
TTCGCAACAAGAATGAGATAGACAATTGAATGTGGGACATTTTTCTGGCATGTCTTGCTGCTGAGAATCGGACTTCCAGTCAAAACCCTG
TTAGTGACACCCACCTCCTCCAGTTATGCAAATTGATGCTTAGCTTGGCAAGCTTTCAAGGAGGTTTGCTTGGAACAGGAAAGGAATTAA
CAACCCTTTGAGGGTGTCATTTTTACCTTGTAATACACTGTGGAAAATTCTGGAAGACGGTCCTTGCCTGAAAAGGTGCAACTTAGCATT
AGGTTGTTATCAGAAACCTTGTCAAGTCTGATGGGAAATGAATAGATGCTGCTTTATTTCCTTGATAACTTCTTTGGAAGTCTGAAATAA
ATCCTGCCTTCAGTAACTGAAACCATTTATTAAAAATAGCAAGAAACAAGATGGGGACCAATTCTATTTTTATTCTTGGGAATTTGAAAG
AGCCACAAGTGATTGGTGTCCGATCTCCCAGCATATACTGTACACTATTTTGTATTTCTCCTGAACCAAAACCAAGTACTTAGCACTCAA
GAAACAGATGCCCTGTGTGTGACCGAGGGGAGTGTTTTTCCACAACAGGTTCCACTTCTGAACACTTGGAAGGACCTTGCCTGATTCATG
GTGAAACACAGAGGTTTTGGTTGGAGATAAATTTGGGGTCAGTTACTGTTCAAAATTGTGAAAGTAGTTCCCAGGAAGACAGCATTAGTG
ACTCCGCAGTGCTTTGGGTAATAGATTTTGAAAAGCAATTGTGAGTTGGGGATTCCATCATTTCATTTAAGAGGTGAAGAGGGATTTAAT
TATTTAATACGCCGGGTGCAAACTTGTTAAATTCCTCTTTCCCTGTCCCTGCTTGGTGGAGCTGCCACGTGTGGTTCAGTTCTAAGTTCT
GGACTAGTGCCACTCGATATCATTGGGAATAAATCGTTGTTCAACAGTCTGTTCCACAAACAACAGTAATTGAATTTCACAGACTTTATC
CTGATTAGTGGAAATCAAATAATGGAGTGGAATCCCCATGTGTTTTCTCTTGCACAAACTTATTAGACTTGATTAGAAAACTGTTTGGAG
GAAAAACTTGCCAGTAAGTTTTTTGGTTGTTGTTTTGTTTTTTTTGAAAAACGACGCAACACCATAAAGTGTAAAATTAGGGGTTCTGGC
CAAGAGAGGTACTAGATTTTTTTAATGCCGAGAAAAGTCCATGCCACAGAAGTTATTGTGTATGTCTCTAGGGAGCTTTAAGAATTTCAC
GTTTGAACTTTACAGCTGTTTACCAATTAAATGGCAAGCTGGAAAAATACATTTTGAGAGGGGTAGAAAGAATAAGAATATAATTAAAAG
TATGCTAACAAAATAAGCAGTACATATTTTTTTAGAAAATGCAGTTTAGGCCAGGCACGGTAGCTCGTGCCTGTAATCCCAGCACTTTGG
GAGGCCGAGGCAGGTGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGGACAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAA
AATTAGCCAACGATGGTGATGCCTGTCTGTAATCCCAGCTACTCTGGAGGCTGAGGCAGGAGAATCGCTTGAACCGGGGAGGCAGAGGTT
GTAGTGAGCCAAGATTGCGCCACTGCACTCCAGCCTGGGCAACAGAGCAAGACTCCGTCTCAAAAAAGGAAAGAAAATGCAGTTTCATTC
CAGCCATCCTTAGATTTCTTTTCCCCTTAAAGTGGCTGAATCCATTGGAGATGTGATTTATTTTGCAGATCCACCAATTCCAAACTTCAG
GAATATTCAAGCGGGAGTCATGTGTAAGTGACAGCTTTGACAAAGAGAGACTGTGGCTGGGTGGCCCGGGTGTTGCCCACGCGGAGCAAG
GATTGGTTCATTCAACGGATGGAGAGTACAGGATGGCTGGGACCTGGGAAGTTCCAGAATCTGAAAAGAGGGCAGGGCAAGAAGGAGCCA
GAAGAGAGGTCCCACCCCTCAGTTGGCAGTGGGGCACGGAGGTCCGCATCAGCCAAGAACGTCCCCAGGATGCCGTGGGCACCTCATTTC
ACCCCACGTTTTTGGCACAGTCTACTTTTTAGGTATTTTGTAAAGGAACTTCTCAGGATTGATTATTTGCCAGAGGAACAATTAGGCCAA
GAGAAACTTGCTTGACAGCCATGTGTAAAACACGTCTGTCCTAATCAAACTAGAGATGCCTCAAGGCCCACGCAGGACACAGGCAGGTTC
AAGGTCATGCACCTGGAAATTTGTAGGGGAGGGTCAAGCAACTGAGGCCAAAGGGGGCCGGTAAAGTGGCTTCTGGGGTCTGAGCATCTG
GAAGGCTCCTGGCAGCAGTTACCTGACAGTGTCGTTGAGGGGCACGGCAGCTGGGCCCTCACCGTTTCCGCCAGCTCTGCTGAGCCAGCC
CAGCCCATGCATTCCGAACATCCGACAGCTTCTTTCTCCAGAATGTCTTCTGTCAGAGACTTCCAGGAAAGGAGCTCCCTCCTGTCTCAC
TGCTGTCAGCGTGGGAGCCCTGCTCCCCAGGCTCCACGTCCCCGGAAGGTCCATCTTGTCCTGGAGCACACCCAGCCCCATTCAGGGTCA
GTGCAGGAGGGAACAGGGAATCTGCATTTCAGTAAGCTCCCCAGGTGAGGCTGCAGAGCAGAAACCACGGCTTTCAGACGTGAGCAGGCT
CCCTGGGCTCTTGGTGTCACCCTGTTAGCCACATCTGCGGAATGTGGAAGGCAGAACATAGCCACGCTGCTTAGTGCTGCCAGCGAACCT
CAGGTTGCATCAGTGGCTGGAATCTATCACAGCTGTTGGGGATACGTAACTCCCAGCAATAAATCCAGTATTTTCTTCCCTGCCCTGAGC
TTCCTCTGGGTTTCTTATCAGCAGCTATTACACACAGATGTCCAGTGCTTCTAAACTAAATTGTACTGTGTAACTTTTACATCACACTTG
TGTGCTTAAAAAGCACACCGTGGGTAGTGACTGGGCCAAGAGACATCACAAAGCTTCCTGATAAATTTGAATCCAGCCACGGCAAGAGCG
ACGTGCGGGTACCTGGTCCCTGATGCTTGGGTGCCCCGTTGAGCCTCGGGTACTTCTTGGACACTATTGTGAGAGCAGCCATCCTGGTGT
CTCTGCCAGCATCTTGGGGAACGCTGTGATGGTAAAATATCTGTCTCTCCTCTGGGAATCAGGGCAGCCCTGAGAAGTGAGCAGTTCCCT
TTACAGATGGATAATTGTTTGTGTAAGACCAACCAGATAAAGTCCAAACTGTGTAGAACACACGTGTGCCTCACACATAGCCATCTGAGT
AAAATATTTTTTCCAATGTAGATTTATAATTAGAAATGACAGATTTATAATATAGACTTCAGTAAGTTGGGCACAGCTGTCACTTTCGTG
GTATCAATAAAAGGCTAGAAACCTTGGGTGTCCTTGGCAACCTAGCCTTTGACATTGATGTTTTTCCATAGGATTTTCTTCATTTGGGTT
GGAATAAAAATGCATTTTTATTCACAAGGCACAGACAGATAAGAATATCATAAGCAGGGAAGTGTCTCCAAAGGTCAGGACATATGTTTT
TCTGTTGAGTGCTATATGTGGAGGTCATTGCAAGTTCCCTGATATGAGTATGGTTTCGCTTGCTACATTGTGCCTATTAAAGTAAAATTT
TACACAAGCCTCGCATTTCTAAGATTAGTGTTCCTGAATGAAATGTTAAGAAAACATTAAAAGATTATCTCTTTTTAAGATGGAGGAAAA
AAAGTGAACAAAGCTAATTAATCTATCATGAAAATTGCACAAAATAACATTTCTTAACAAATTTAATACAATTTTGTGTTCTTTGTTGCT
AGTGGTATAAAACGAGATTTTTTTCCCTCATTTTTCTCATTGTAGATGTCATCTCTCACATTTATATCAGTGAGGTTTGAAATTCTGTGT
AGCAGTTACTCAGCACATATGAGAGGGCAGCGAATGAATGAGATTTGTCATGTGCTAATAAAAGCTGAATTTTTGTAATCTAAAATGATG
TATTTTCTACTATTGCTGTTAATTTGCATTGTTAAAAATTCTTAAAGTTTAATATGTTATGTTCAGTCATTGAAAGCGACCACTCATTTT
TTTCTTAAAGTTGATGCCTTTTCTGCTGTGCTAGAGTCAGTATTTTGCTTCTGGCAGGAGAGCTGCAAACTGTGTATCCTCAAACAGATG
CAAAAAGTAGTGCTTTGCAAAACGTTTGTTTTCTGTTTATCTCAGATTAACATCCTTTAATACAAGTTTCTTAAGTGTAACTTGTATTTC
TGAAAATGCTTAAAATTATTTTATATTTCCCTTTGGGAATTTTTCTCTATTTCCAGCACGCTGATTTGATTTAAAAATGTAATAAGACCA
AGAGTTGGAGTAAAGGGATATTCATTCCATGTTAAAAGTGGCTTCATAGCTACTGACAAATGTCTGAACTATTGTCGTGCCCTTCAAAAC
TGGAGTTTTCTAAAATAATCTTATTTTTATACTTGTATGTTCCAGCAATTTAAGATATATACCATTGAAAGGGAAATAAAACATTTTTGT

>351_351_9_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000347800_BACE2_chr21_42598193_ENST00000347667_length(amino acids)=781AA_BP=2
MPPCETCLSPSAMIMRLPQPHGTNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSLPRRAAVNIEFRD
LSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPH
LTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKG
LAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDS
DHKRDLGGDAEVNPFLWHRPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSLQILVDTGSSNFAVAGTPHSYIDTYFDTERSST
YRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNV
FSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFD
AVVEAVARASLLYIQPMMGAGLNYECYRFGISPSTNALVIGATVMEGFYVIFDRAQKRVGFAASPCAEIAGAAVSEISGPFSTEDVASNC

--------------------------------------------------------------
>351_351_10_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000361802_BACE2_chr21_42598193_ENST00000328735_length(transcript)=3454nt_BP=1405nt
GAGCCGGAGCCGGATCCCAGCCGGAGCCCAAGCGCAGCCCGCACCCCGCGCAGCGGCTGAGCCGGGAGCCAGCGCAGCCTCGGCCCCGCA
GCTCAAGCCTCGTCCCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCCCCGGGGCATGGCCTGTCTGATGGCCGCTTTCTCGGTCGGCAC
CGCCATGAATGCCAGCAGTTACTCTGCAGAGATGACGGAGCCCAAGTCGGTGTGTGTCTCGGTGGATGAGGTGGTGTCCAGCAACATGGA
GGCCACTGAGACGGACCTGCTGAATGGACATCTGAAAAAAGTAGATAATAACCTCACGGAAGCCCAGCGCTTCTCCTCCTTGCCTCGGAG
GGCAGCTGTGAACATTGAATTCAGGGACCTTTCCTATTCGGTTCCTGAAGGACCCTGGTGGAGGAAGAAAGGATACAAGACCCTCCTGAA
AGGAATTTCCGGGAAGTTCAATAGTGGTGAGTTGGTGGCCATTATGGGTCCTTCCGGGGCCGGGAAGTCCACGCTGATGAACATCCTGGC
TGGATACAGGGAGACGGGCATGAAGGGGGCCGTCCTCATCAACGGCCTGCCCCGGGACCTGCGCTGCTTCCGGAAGGTGTCCTGCTACAT
CATGCAGGATGACATGCTGCTGCCGCATCTCACTGTGCAGGAGGCCATGATGGTGTCGGCACATCTGAAGCTTCAGGAGAAGGATGAAGG
CAGAAGGGAAATGGTCAAGGAGATACTGACAGCGCTGGGCTTGCTGTCTTGCGCCAACACGCGGACCGGGAGCCTGTCAGGTGGTCAGCG
CAAGCGCCTGGCCATCGCGCTGGAGCTGGTGAACAACCCTCCAGTCATGTTCTTCGATGAGCCCACCAGCGGCCTGGACAGCGCCTCCTG
CTTCCAGGTGGTCTCGCTGATGAAAGGGCTCGCTCAAGGGGGTCGCTCCATCATTTGCACCATCCACCAGCCCAGCGCCAAACTCTTCGA
GCTGTTCGACCAGCTTTACGTCCTGAGTCAAGGACAATGTGTGTACCGGGGAAAAGTCTGCAATCTTGTGCCATATTTGAGGGATTTGGG
TCTGAACTGCCCAACCTACCACAACCCAGCAGATTTTGTCATGGAGGTTGCATCCGGCGAGTACGGTGATCAGAACAGTCGGCTGGTGAG
AGCGGTTCGGGAGGGCATGTGTGACTCAGACCACAAGAGAGACCTCGGGGGTGATGCCGAGGTGAACCCTTTTCTTTGGCACCGGCCCTC
TGAAGAGGTAAAGCAGACAAAACGATTAAAGGGGTTGAGAAAGGACTCCTCGTCCATGGAAGGCTGCCACAGCTTCTCTGCCAGCTGCCT
CACGCAGTTCTGCATCCTCTTCAAGAGGACCTTCCTCAGCATCATGAGGGACTCGCTACAGATTCTCGTTGACACTGGAAGCAGTAACTT
TGCCGTGGCAGGAACCCCGCACTCCTACATAGACACGTACTTTGACACAGAGAGGTCTAGCACATACCGCTCCAAGGGCTTTGACGTCAC
AGTGAAGTACACACAAGGAAGCTGGACGGGCTTCGTTGGGGAAGACCTCGTCACCATCCCCAAAGGCTTCAATACTTCTTTTCTTGTCAA
CATTGCCACTATTTTTGAATCAGAGAATTTCTTTTTGCCTGGGATTAAATGGAATGGAATACTTGGCCTAGCTTATGCCACACTTGCCAA
GCCATCAAGTTCTCTGGAGACCTTCTTCGACTCCCTGGTGACACAAGCAAACATCCCCAACGTTTTCTCCATGCAGATGTGTGGAGCCGG
CTTGCCCGTTGCTGGATCTGGGACCAACGGAGGTAGTCTTGTCTTGGGTGGAATTGAACCAAGTTTGTATAAAGGAGACATCTGGTATAC
CCCTATTAAGGAAGAGTGGTACTACCAGATAGAAATTCTGAAATTGGAAATTGGAGGCCAAAGCCTTAATCTGGACTGCAGAGAGTATAA
CGCAGACAAGGCCATCGTGGACAGTGGCACCACGCTGCTGCGCCTGCCCCAGAAGGTGTTTGATGCGGTGGTGGAAGCTGTGGCCCGCGC
ATCTCTGATTCCAGAATTCTCTGATGGTTTCTGGACTGGGTCCCAGCTGGCGTGCTGGACGAATTCGGAAACACCTTGGTCTTACTTCCC
TAAAATCTCCATCTACCTGAGAGACGAGAACTCCAGCAGGTCATTCCGTATCACAATCCTGCCTCAGAAATTGCAGGTGCTGCAGTGTCT
GAAATTTCCGGGCCTTTCTCAACAGAGGATGTAGCCAGCAACTGTGTCCCCGCTCAGTCTTTGAGCGAGCCCATTTTGTGGATTGTGTCC
TATGCGCTCATGAGCGTCTGTGGAGCCATCCTCCTTGTCTTAATCGTCCTGCTGCTGCTGCCGTTCCGGTGTCAGCGTCGCCCCCGTGAC
CCTGAGGTCGTCAATGATGAGTCCTCTCTGGTCAGACATCGCTGGAAATGAATAGCCAGGCCTGACCTCAAGCAACCATGAACTCAGCTA
TTAAGAAAATCACATTTCCAGGGCAGCAGCCGGGATCGATGGTGGCGCTTTCTCCTGTGCCCACCCGTCTTCAATCTCTGTTCTGCTCCC
AGATGCCTTCTAGATTCACTGTCTTTTGATTCTTGATTTTCAAGCTTTCAAATCCTCCCTACTTCCAAGAAAAATAATTAAAAAAAAAAC
TTCATTCTAAACCAAAACAGAGTGGATTGGGCTGCAGGCTCTATGGGGTTCGTTATGCCAAAGTGTCTACATGTGCCACCAACATAAAAC
AAAACCAAGCCTTGGCTCGTTCTCTTCTCTCTTCAATCTCTGGAAAAATAAGTACATATAGTTGATAACCCCTCTTAGCTTACAGGAAGC
TTTTTGTATTAATTGCCTTTGAGGTTATTTTCCGCCAGACCTCAACCTGGGTCAAAGTGGTACAGGAAGGCTTGCAGTATGATGGCAGGA
GAATCAGCCTGGGGCCTGGGGATGTAACCAAGCTGTACCCTTGAGACCTGGAACCAGAGCCACAGGCCCCTTTTGTGGGTTTCTCTGTGC
TCTGAATGGGAGCCAGAATTCACTAGGAGGTCATCAACCGATGGTCCTCACAAGCCTCTTCTGAAGATGGAAGGCCTTTTGCCCGTTGAG
GTAGAGGGGAAGGAAATCTCCTCTTTTGTACCCAATACTTATGTTGTATTGTTGGTGCGAAAGTAAAAACACTACCTCTTTTGAGACTTT
GCCCAGGGTCCTGTGCCTGGATGGGGGTGCAGGCAGCCTTGACCACGGCTGTTCCCCTCACCCAAAAGAATTATCATCCCAACAGCCAAG
ACCCAACAGGTGCTGAACTGTGCATCAACCAGGAAGAGTTCTATCCCCAAGCTGGCCACTATCACATATGCTTACTCTTGCTTAAAATTA

>351_351_10_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000361802_BACE2_chr21_42598193_ENST00000328735_length(amino acids)=712AA_BP=420
MACLMAAFSVGTAMNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSLPRRAAVNIEFRDLSYSVPEGP
WWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMV
SAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSII
CTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGD
AEVNPFLWHRPSEEVKQTKRLKGLRKDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSLQILVDTGSSNFAVAGTPHSYIDTYFDTER
SSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANI
PNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQK

--------------------------------------------------------------
>351_351_11_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000361802_BACE2_chr21_42598193_ENST00000330333_length(transcript)=3623nt_BP=1405nt
GAGCCGGAGCCGGATCCCAGCCGGAGCCCAAGCGCAGCCCGCACCCCGCGCAGCGGCTGAGCCGGGAGCCAGCGCAGCCTCGGCCCCGCA
GCTCAAGCCTCGTCCCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCCCCGGGGCATGGCCTGTCTGATGGCCGCTTTCTCGGTCGGCAC
CGCCATGAATGCCAGCAGTTACTCTGCAGAGATGACGGAGCCCAAGTCGGTGTGTGTCTCGGTGGATGAGGTGGTGTCCAGCAACATGGA
GGCCACTGAGACGGACCTGCTGAATGGACATCTGAAAAAAGTAGATAATAACCTCACGGAAGCCCAGCGCTTCTCCTCCTTGCCTCGGAG
GGCAGCTGTGAACATTGAATTCAGGGACCTTTCCTATTCGGTTCCTGAAGGACCCTGGTGGAGGAAGAAAGGATACAAGACCCTCCTGAA
AGGAATTTCCGGGAAGTTCAATAGTGGTGAGTTGGTGGCCATTATGGGTCCTTCCGGGGCCGGGAAGTCCACGCTGATGAACATCCTGGC
TGGATACAGGGAGACGGGCATGAAGGGGGCCGTCCTCATCAACGGCCTGCCCCGGGACCTGCGCTGCTTCCGGAAGGTGTCCTGCTACAT
CATGCAGGATGACATGCTGCTGCCGCATCTCACTGTGCAGGAGGCCATGATGGTGTCGGCACATCTGAAGCTTCAGGAGAAGGATGAAGG
CAGAAGGGAAATGGTCAAGGAGATACTGACAGCGCTGGGCTTGCTGTCTTGCGCCAACACGCGGACCGGGAGCCTGTCAGGTGGTCAGCG
CAAGCGCCTGGCCATCGCGCTGGAGCTGGTGAACAACCCTCCAGTCATGTTCTTCGATGAGCCCACCAGCGGCCTGGACAGCGCCTCCTG
CTTCCAGGTGGTCTCGCTGATGAAAGGGCTCGCTCAAGGGGGTCGCTCCATCATTTGCACCATCCACCAGCCCAGCGCCAAACTCTTCGA
GCTGTTCGACCAGCTTTACGTCCTGAGTCAAGGACAATGTGTGTACCGGGGAAAAGTCTGCAATCTTGTGCCATATTTGAGGGATTTGGG
TCTGAACTGCCCAACCTACCACAACCCAGCAGATTTTGTCATGGAGGTTGCATCCGGCGAGTACGGTGATCAGAACAGTCGGCTGGTGAG
AGCGGTTCGGGAGGGCATGTGTGACTCAGACCACAAGAGAGACCTCGGGGGTGATGCCGAGGTGAACCCTTTTCTTTGGCACCGGCCCTC
TGAAGAGGTAAAGCAGACAAAACGATTAAAGGGGTTGAGAAAGGACTCCTCGTCCATGGAAGGCTGCCACAGCTTCTCTGCCAGCTGCCT
CACGCAGTTCTGCATCCTCTTCAAGAGGACCTTCCTCAGCATCATGAGGGACTCGCTACAGATTCTCGTTGACACTGGAAGCAGTAACTT
TGCCGTGGCAGGAACCCCGCACTCCTACATAGACACGTACTTTGACACAGAGAGGTCTAGCACATACCGCTCCAAGGGCTTTGACGTCAC
AGTGAAGTACACACAAGGAAGCTGGACGGGCTTCGTTGGGGAAGACCTCGTCACCATCCCCAAAGGCTTCAATACTTCTTTTCTTGTCAA
CATTGCCACTATTTTTGAATCAGAGAATTTCTTTTTGCCTGGGATTAAATGGAATGGAATACTTGGCCTAGCTTATGCCACACTTGCCAA
GCCATCAAGTTCTCTGGAGACCTTCTTCGACTCCCTGGTGACACAAGCAAACATCCCCAACGTTTTCTCCATGCAGATGTGTGGAGCCGG
CTTGCCCGTTGCTGGATCTGGGACCAACGGAGGTAGTCTTGTCTTGGGTGGAATTGAACCAAGTTTGTATAAAGGAGACATCTGGTATAC
CCCTATTAAGGAAGAGTGGTACTACCAGATAGAAATTCTGAAATTGGAAATTGGAGGCCAAAGCCTTAATCTGGACTGCAGAGAGTATAA
CGCAGACAAGGCCATCGTGGACAGTGGCACCACGCTGCTGCGCCTGCCCCAGAAGGTGTTTGATGCGGTGGTGGAAGCTGTGGCCCGCGC
ATCTCTGATTCCAGAATTCTCTGATGGTTTCTGGACTGGGTCCCAGCTGGCGTGCTGGACGAATTCGGAAACACCTTGGTCTTACTTCCC
TAAAATCTCCATCTACCTGAGAGACGAGAACTCCAGCAGGTCATTCCGTATCACAATCCTGCCTCAGCTTTACATTCAGCCCATGATGGG
GGCCGGCCTGAATTATGAATGTTACCGATTCGGCATTTCCCCATCCACAAATGCGCTGGTGATCGGTGCCACGGTGATGGAGGGCTTCTA
CGTCATCTTCGACAGAGCCCAGAAGAGGGTGGGCTTCGCAGCGAGCCCCTGTGCAGAAATTGCAGGTGCTGCAGTGTCTGAAATTTCCGG
GCCTTTCTCAACAGAGGATGTAGCCAGCAACTGTGTCCCCGCTCAGTCTTTGAGCGAGCCCATTTTGTGGATTGTGTCCTATGCGCTCAT
GAGCGTCTGTGGAGCCATCCTCCTTGTCTTAATCGTCCTGCTGCTGCTGCCGTTCCGGTGTCAGCGTCGCCCCCGTGACCCTGAGGTCGT
CAATGATGAGTCCTCTCTGGTCAGACATCGCTGGAAATGAATAGCCAGGCCTGACCTCAAGCAACCATGAACTCAGCTATTAAGAAAATC
ACATTTCCAGGGCAGCAGCCGGGATCGATGGTGGCGCTTTCTCCTGTGCCCACCCGTCTTCAATCTCTGTTCTGCTCCCAGATGCCTTCT
AGATTCACTGTCTTTTGATTCTTGATTTTCAAGCTTTCAAATCCTCCCTACTTCCAAGAAAAATAATTAAAAAAAAAACTTCATTCTAAA
CCAAAACAGAGTGGATTGGGCTGCAGGCTCTATGGGGTTCGTTATGCCAAAGTGTCTACATGTGCCACCAACATAAAACAAAACCAAGCC
TTGGCTCGTTCTCTTCTCTCTTCAATCTCTGGAAAAATAAGTACATATAGTTGATAACCCCTCTTAGCTTACAGGAAGCTTTTTGTATTA
ATTGCCTTTGAGGTTATTTTCCGCCAGACCTCAACCTGGGTCAAAGTGGTACAGGAAGGCTTGCAGTATGATGGCAGGAGAATCAGCCTG
GGGCCTGGGGATGTAACCAAGCTGTACCCTTGAGACCTGGAACCAGAGCCACAGGCCCCTTTTGTGGGTTTCTCTGTGCTCTGAATGGGA
GCCAGAATTCACTAGGAGGTCATCAACCGATGGTCCTCACAAGCCTCTTCTGAAGATGGAAGGCCTTTTGCCCGTTGAGGTAGAGGGGAA
GGAAATCTCCTCTTTTGTACCCAATACTTATGTTGTATTGTTGGTGCGAAAGTAAAAACACTACCTCTTTTGAGACTTTGCCCAGGGTCC
TGTGCCTGGATGGGGGTGCAGGCAGCCTTGACCACGGCTGTTCCCCTCACCCAAAAGAATTATCATCCCAACAGCCAAGACCCAACAGGT
GCTGAACTGTGCATCAACCAGGAAGAGTTCTATCCCCAAGCTGGCCACTATCACATATGCTTACTCTTGCTTAAAATTAATAAATCATGT

>351_351_11_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000361802_BACE2_chr21_42598193_ENST00000330333_length(amino acids)=834AA_BP=420
MACLMAAFSVGTAMNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSLPRRAAVNIEFRDLSYSVPEGP
WWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMV
SAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSII
CTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGD
AEVNPFLWHRPSEEVKQTKRLKGLRKDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSLQILVDTGSSNFAVAGTPHSYIDTYFDTER
SSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANI
PNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQK
VFDAVVEAVARASLIPEFSDGFWTGSQLACWTNSETPWSYFPKISIYLRDENSSRSFRITILPQLYIQPMMGAGLNYECYRFGISPSTNA
LVIGATVMEGFYVIFDRAQKRVGFAASPCAEIAGAAVSEISGPFSTEDVASNCVPAQSLSEPILWIVSYALMSVCGAILLVLIVLLLLPF

--------------------------------------------------------------
>351_351_12_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000361802_BACE2_chr21_42598193_ENST00000347667_length(transcript)=9394nt_BP=1405nt
GAGCCGGAGCCGGATCCCAGCCGGAGCCCAAGCGCAGCCCGCACCCCGCGCAGCGGCTGAGCCGGGAGCCAGCGCAGCCTCGGCCCCGCA
GCTCAAGCCTCGTCCCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCCCCGGGGCATGGCCTGTCTGATGGCCGCTTTCTCGGTCGGCAC
CGCCATGAATGCCAGCAGTTACTCTGCAGAGATGACGGAGCCCAAGTCGGTGTGTGTCTCGGTGGATGAGGTGGTGTCCAGCAACATGGA
GGCCACTGAGACGGACCTGCTGAATGGACATCTGAAAAAAGTAGATAATAACCTCACGGAAGCCCAGCGCTTCTCCTCCTTGCCTCGGAG
GGCAGCTGTGAACATTGAATTCAGGGACCTTTCCTATTCGGTTCCTGAAGGACCCTGGTGGAGGAAGAAAGGATACAAGACCCTCCTGAA
AGGAATTTCCGGGAAGTTCAATAGTGGTGAGTTGGTGGCCATTATGGGTCCTTCCGGGGCCGGGAAGTCCACGCTGATGAACATCCTGGC
TGGATACAGGGAGACGGGCATGAAGGGGGCCGTCCTCATCAACGGCCTGCCCCGGGACCTGCGCTGCTTCCGGAAGGTGTCCTGCTACAT
CATGCAGGATGACATGCTGCTGCCGCATCTCACTGTGCAGGAGGCCATGATGGTGTCGGCACATCTGAAGCTTCAGGAGAAGGATGAAGG
CAGAAGGGAAATGGTCAAGGAGATACTGACAGCGCTGGGCTTGCTGTCTTGCGCCAACACGCGGACCGGGAGCCTGTCAGGTGGTCAGCG
CAAGCGCCTGGCCATCGCGCTGGAGCTGGTGAACAACCCTCCAGTCATGTTCTTCGATGAGCCCACCAGCGGCCTGGACAGCGCCTCCTG
CTTCCAGGTGGTCTCGCTGATGAAAGGGCTCGCTCAAGGGGGTCGCTCCATCATTTGCACCATCCACCAGCCCAGCGCCAAACTCTTCGA
GCTGTTCGACCAGCTTTACGTCCTGAGTCAAGGACAATGTGTGTACCGGGGAAAAGTCTGCAATCTTGTGCCATATTTGAGGGATTTGGG
TCTGAACTGCCCAACCTACCACAACCCAGCAGATTTTGTCATGGAGGTTGCATCCGGCGAGTACGGTGATCAGAACAGTCGGCTGGTGAG
AGCGGTTCGGGAGGGCATGTGTGACTCAGACCACAAGAGAGACCTCGGGGGTGATGCCGAGGTGAACCCTTTTCTTTGGCACCGGCCCTC
TGAAGAGGTAAAGCAGACAAAACGATTAAAGGGGTTGAGAAAGGACTCCTCGTCCATGGAAGGCTGCCACAGCTTCTCTGCCAGCTGCCT
CACGCAGTTCTGCATCCTCTTCAAGAGGACCTTCCTCAGCATCATGAGGGACTCGCTACAGATTCTCGTTGACACTGGAAGCAGTAACTT
TGCCGTGGCAGGAACCCCGCACTCCTACATAGACACGTACTTTGACACAGAGAGGTCTAGCACATACCGCTCCAAGGGCTTTGACGTCAC
AGTGAAGTACACACAAGGAAGCTGGACGGGCTTCGTTGGGGAAGACCTCGTCACCATCCCCAAAGGCTTCAATACTTCTTTTCTTGTCAA
CATTGCCACTATTTTTGAATCAGAGAATTTCTTTTTGCCTGGGATTAAATGGAATGGAATACTTGGCCTAGCTTATGCCACACTTGCCAA
GCCATCAAGTTCTCTGGAGACCTTCTTCGACTCCCTGGTGACACAAGCAAACATCCCCAACGTTTTCTCCATGCAGATGTGTGGAGCCGG
CTTGCCCGTTGCTGGATCTGGGACCAACGGAGGTAGTCTTGTCTTGGGTGGAATTGAACCAAGTTTGTATAAAGGAGACATCTGGTATAC
CCCTATTAAGGAAGAGTGGTACTACCAGATAGAAATTCTGAAATTGGAAATTGGAGGCCAAAGCCTTAATCTGGACTGCAGAGAGTATAA
CGCAGACAAGGCCATCGTGGACAGTGGCACCACGCTGCTGCGCCTGCCCCAGAAGGTGTTTGATGCGGTGGTGGAAGCTGTGGCCCGCGC
ATCTCTGCTTTACATTCAGCCCATGATGGGGGCCGGCCTGAATTATGAATGTTACCGATTCGGCATTTCCCCATCCACAAATGCGCTGGT
GATCGGTGCCACGGTGATGGAGGGCTTCTACGTCATCTTCGACAGAGCCCAGAAGAGGGTGGGCTTCGCAGCGAGCCCCTGTGCAGAAAT
TGCAGGTGCTGCAGTGTCTGAAATTTCCGGGCCTTTCTCAACAGAGGATGTAGCCAGCAACTGTGTCCCCGCTCAGTCTTTGAGCGAGCC
CATTTTGTGGATTGTGTCCTATGCGCTCATGAGCGTCTGTGGAGCCATCCTCCTTGTCTTAATCGTCCTGCTGCTGCTGCCGTTCCGGTG
TCAGCGTCGCCCCCGTGACCCTGAGGTCGTCAATGATGAGTCCTCTCTGGTCAGACATCGCTGGAAATGAATAGCCAGGCCTGACCTCAA
GCAACCATGAACTCAGCTATTAAGAAAATCACATTTCCAGGGCAGCAGCCGGGATCGATGGTGGCGCTTTCTCCTGTGCCCACCCGTCTT
CAATCTCTGTTCTGCTCCCAGATGCCTTCTAGATTCACTGTCTTTTGATTCTTGATTTTCAAGCTTTCAAATCCTCCCTACTTCCAAGAA
AAATAATTAAAAAAAAAACTTCATTCTAAACCAAAACAGAGTGGATTGGGCTGCAGGCTCTATGGGGTTCGTTATGCCAAAGTGTCTACA
TGTGCCACCAACATAAAACAAAACCAAGCCTTGGCTCGTTCTCTTCTCTCTTCAATCTCTGGAAAAATAAGTACATATAGTTGATAACCC
CTCTTAGCTTACAGGAAGCTTTTTGTATTAATTGCCTTTGAGGTTATTTTCCGCCAGACCTCAACCTGGGTCAAAGTGGTACAGGAAGGC
TTGCAGTATGATGGCAGGAGAATCAGCCTGGGGCCTGGGGATGTAACCAAGCTGTACCCTTGAGACCTGGAACCAGAGCCACAGGCCCCT
TTTGTGGGTTTCTCTGTGCTCTGAATGGGAGCCAGAATTCACTAGGAGGTCATCAACCGATGGTCCTCACAAGCCTCTTCTGAAGATGGA
AGGCCTTTTGCCCGTTGAGGTAGAGGGGAAGGAAATCTCCTCTTTTGTACCCAATACTTATGTTGTATTGTTGGTGCGAAAGTAAAAACA
CTACCTCTTTTGAGACTTTGCCCAGGGTCCTGTGCCTGGATGGGGGTGCAGGCAGCCTTGACCACGGCTGTTCCCCTCACCCAAAAGAAT
TATCATCCCAACAGCCAAGACCCAACAGGTGCTGAACTGTGCATCAACCAGGAAGAGTTCTATCCCCAAGCTGGCCACTATCACATATGC
TTACTCTTGCTTAAAATTAATAAATCATGTTTTGATGAGAAAAAACTATTCTATTTCACTAGCTTAGTTGTCTCTTTTTCCAAATCTTCT
CTGGAAGTAGGTTGGCTATTACCCTGTTGGGAAACAGGGAAATGGCCTGATGCCCCTATTTCTGACCAGCTGTCAGGGAAGGAAGATGCA
AGATGTGCAGAAGACACAAGGTAACGTCTACTTATCCCCGTGCTTCGAAACCGTGTGTTTCCCTTTGCAGAACTGGTTAGCCTCAAGCAT
ACCCATCCAATCAGCTTAAATTGTTCAGCAGTTGACCTCTGTGCTTCTTCCTTTGGGGGTGTTTAATCTTTGGTAACAGTTGTGCAGTGG
TAGCCTTATTTCGGGGGGCAGTCCCTACTTTCTGTCACTTATCGAGGCCTTTGCCAAAGAAAAGTGGAAGCCGTTTCCTTGACATAGCCT
TATATGACCTGATGTCATTAGGAGAAGAGTTAAAAGACAGTATCCCCTCTCTCCTGCTTGTGTGCCAAGTTCAGTGTTCCCTTTGCATTT
TTTTGGGGTGGGTTGGCTATATTACAGAATTCCACCAAAAGTGCTAAGTGTCCCCTCCTGCAGAAGTATCGTTTGTATTCACAGTAGGCT
ACGTGTGGATGTTTCAGCCATCTGCTCTGCTCCCTGGGTCCCCGGGTCACCACCATACTGAGAAATATAGGACTCTGCCAAAGAGACGTG
GAGGCCACGTCGGCTTGTCATGGTGTCCTGGAAGACTCTCCAGCAGCCAGAAGAACCTTCTGTGCTGTTTTCACTAGAGAAGATTTGAGT
TGCAGCCTCTTGGAAAGAACATGACGGCACGGAACGGGAGGAGGGGGCTCTTGTATCAGGGCCCGTTGTCACATCCGCTCTCAGCTTGTT
GAAAACTCATAATCTCAGAATGCATTTCACACGGAGAGATGTCTGGAAGTCCAATTCTCATCCCATTGGCTTTTTCCGTGGTTGCTGTTT
TGTGGGCCGCTTTGCACAGGAGTGAAGCCAACACCCCTAGATTGTGCCTTCACCCTTGCTGTGAAAAATTCAAAGCCCTGAAATAAGAGG
AGGGAATCGCAGACATGCCCTGATTAGTTTTCCTGCTTATTTCTTCATACAGGCATCTTCTGTTCCGTTGTATTGTGTTAGGTTTCAGAG
GCGGGGAGCTTCCTCCTGCAGCAGATGAACAGGCATAGTTCTTAAAATACAGGAAAGTAACAAGTGAGGTTTCCAGGTAGAGTAGGTGAA
TGAAGTTTGCCGTCATGCTCTGTATTTCATATCAGATTTCTTTATCTTTTCATATCGCATGTCATTGGATGTGACATTTTGATGAAAATA
CTGAAACTACAAAAGCATAACTTCGCAACAAGAATGAGATAGACAATTGAATGTGGGACATTTTTCTGGCATGTCTTGCTGCTGAGAATC
GGACTTCCAGTCAAAACCCTGTTAGTGACACCCACCTCCTCCAGTTATGCAAATTGATGCTTAGCTTGGCAAGCTTTCAAGGAGGTTTGC
TTGGAACAGGAAAGGAATTAACAACCCTTTGAGGGTGTCATTTTTACCTTGTAATACACTGTGGAAAATTCTGGAAGACGGTCCTTGCCT
GAAAAGGTGCAACTTAGCATTAGGTTGTTATCAGAAACCTTGTCAAGTCTGATGGGAAATGAATAGATGCTGCTTTATTTCCTTGATAAC
TTCTTTGGAAGTCTGAAATAAATCCTGCCTTCAGTAACTGAAACCATTTATTAAAAATAGCAAGAAACAAGATGGGGACCAATTCTATTT
TTATTCTTGGGAATTTGAAAGAGCCACAAGTGATTGGTGTCCGATCTCCCAGCATATACTGTACACTATTTTGTATTTCTCCTGAACCAA
AACCAAGTACTTAGCACTCAAGAAACAGATGCCCTGTGTGTGACCGAGGGGAGTGTTTTTCCACAACAGGTTCCACTTCTGAACACTTGG
AAGGACCTTGCCTGATTCATGGTGAAACACAGAGGTTTTGGTTGGAGATAAATTTGGGGTCAGTTACTGTTCAAAATTGTGAAAGTAGTT
CCCAGGAAGACAGCATTAGTGACTCCGCAGTGCTTTGGGTAATAGATTTTGAAAAGCAATTGTGAGTTGGGGATTCCATCATTTCATTTA
AGAGGTGAAGAGGGATTTAATTATTTAATACGCCGGGTGCAAACTTGTTAAATTCCTCTTTCCCTGTCCCTGCTTGGTGGAGCTGCCACG
TGTGGTTCAGTTCTAAGTTCTGGACTAGTGCCACTCGATATCATTGGGAATAAATCGTTGTTCAACAGTCTGTTCCACAAACAACAGTAA
TTGAATTTCACAGACTTTATCCTGATTAGTGGAAATCAAATAATGGAGTGGAATCCCCATGTGTTTTCTCTTGCACAAACTTATTAGACT
TGATTAGAAAACTGTTTGGAGGAAAAACTTGCCAGTAAGTTTTTTGGTTGTTGTTTTGTTTTTTTTGAAAAACGACGCAACACCATAAAG
TGTAAAATTAGGGGTTCTGGCCAAGAGAGGTACTAGATTTTTTTAATGCCGAGAAAAGTCCATGCCACAGAAGTTATTGTGTATGTCTCT
AGGGAGCTTTAAGAATTTCACGTTTGAACTTTACAGCTGTTTACCAATTAAATGGCAAGCTGGAAAAATACATTTTGAGAGGGGTAGAAA
GAATAAGAATATAATTAAAAGTATGCTAACAAAATAAGCAGTACATATTTTTTTAGAAAATGCAGTTTAGGCCAGGCACGGTAGCTCGTG
CCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGGACAACATGGTGAAACCCC
GTCTCTACTAAAAATACAAAAAATTAGCCAACGATGGTGATGCCTGTCTGTAATCCCAGCTACTCTGGAGGCTGAGGCAGGAGAATCGCT
TGAACCGGGGAGGCAGAGGTTGTAGTGAGCCAAGATTGCGCCACTGCACTCCAGCCTGGGCAACAGAGCAAGACTCCGTCTCAAAAAAGG
AAAGAAAATGCAGTTTCATTCCAGCCATCCTTAGATTTCTTTTCCCCTTAAAGTGGCTGAATCCATTGGAGATGTGATTTATTTTGCAGA
TCCACCAATTCCAAACTTCAGGAATATTCAAGCGGGAGTCATGTGTAAGTGACAGCTTTGACAAAGAGAGACTGTGGCTGGGTGGCCCGG
GTGTTGCCCACGCGGAGCAAGGATTGGTTCATTCAACGGATGGAGAGTACAGGATGGCTGGGACCTGGGAAGTTCCAGAATCTGAAAAGA
GGGCAGGGCAAGAAGGAGCCAGAAGAGAGGTCCCACCCCTCAGTTGGCAGTGGGGCACGGAGGTCCGCATCAGCCAAGAACGTCCCCAGG
ATGCCGTGGGCACCTCATTTCACCCCACGTTTTTGGCACAGTCTACTTTTTAGGTATTTTGTAAAGGAACTTCTCAGGATTGATTATTTG
CCAGAGGAACAATTAGGCCAAGAGAAACTTGCTTGACAGCCATGTGTAAAACACGTCTGTCCTAATCAAACTAGAGATGCCTCAAGGCCC
ACGCAGGACACAGGCAGGTTCAAGGTCATGCACCTGGAAATTTGTAGGGGAGGGTCAAGCAACTGAGGCCAAAGGGGGCCGGTAAAGTGG
CTTCTGGGGTCTGAGCATCTGGAAGGCTCCTGGCAGCAGTTACCTGACAGTGTCGTTGAGGGGCACGGCAGCTGGGCCCTCACCGTTTCC
GCCAGCTCTGCTGAGCCAGCCCAGCCCATGCATTCCGAACATCCGACAGCTTCTTTCTCCAGAATGTCTTCTGTCAGAGACTTCCAGGAA
AGGAGCTCCCTCCTGTCTCACTGCTGTCAGCGTGGGAGCCCTGCTCCCCAGGCTCCACGTCCCCGGAAGGTCCATCTTGTCCTGGAGCAC
ACCCAGCCCCATTCAGGGTCAGTGCAGGAGGGAACAGGGAATCTGCATTTCAGTAAGCTCCCCAGGTGAGGCTGCAGAGCAGAAACCACG
GCTTTCAGACGTGAGCAGGCTCCCTGGGCTCTTGGTGTCACCCTGTTAGCCACATCTGCGGAATGTGGAAGGCAGAACATAGCCACGCTG
CTTAGTGCTGCCAGCGAACCTCAGGTTGCATCAGTGGCTGGAATCTATCACAGCTGTTGGGGATACGTAACTCCCAGCAATAAATCCAGT
ATTTTCTTCCCTGCCCTGAGCTTCCTCTGGGTTTCTTATCAGCAGCTATTACACACAGATGTCCAGTGCTTCTAAACTAAATTGTACTGT
GTAACTTTTACATCACACTTGTGTGCTTAAAAAGCACACCGTGGGTAGTGACTGGGCCAAGAGACATCACAAAGCTTCCTGATAAATTTG
AATCCAGCCACGGCAAGAGCGACGTGCGGGTACCTGGTCCCTGATGCTTGGGTGCCCCGTTGAGCCTCGGGTACTTCTTGGACACTATTG
TGAGAGCAGCCATCCTGGTGTCTCTGCCAGCATCTTGGGGAACGCTGTGATGGTAAAATATCTGTCTCTCCTCTGGGAATCAGGGCAGCC
CTGAGAAGTGAGCAGTTCCCTTTACAGATGGATAATTGTTTGTGTAAGACCAACCAGATAAAGTCCAAACTGTGTAGAACACACGTGTGC
CTCACACATAGCCATCTGAGTAAAATATTTTTTCCAATGTAGATTTATAATTAGAAATGACAGATTTATAATATAGACTTCAGTAAGTTG
GGCACAGCTGTCACTTTCGTGGTATCAATAAAAGGCTAGAAACCTTGGGTGTCCTTGGCAACCTAGCCTTTGACATTGATGTTTTTCCAT
AGGATTTTCTTCATTTGGGTTGGAATAAAAATGCATTTTTATTCACAAGGCACAGACAGATAAGAATATCATAAGCAGGGAAGTGTCTCC
AAAGGTCAGGACATATGTTTTTCTGTTGAGTGCTATATGTGGAGGTCATTGCAAGTTCCCTGATATGAGTATGGTTTCGCTTGCTACATT
GTGCCTATTAAAGTAAAATTTTACACAAGCCTCGCATTTCTAAGATTAGTGTTCCTGAATGAAATGTTAAGAAAACATTAAAAGATTATC
TCTTTTTAAGATGGAGGAAAAAAAGTGAACAAAGCTAATTAATCTATCATGAAAATTGCACAAAATAACATTTCTTAACAAATTTAATAC
AATTTTGTGTTCTTTGTTGCTAGTGGTATAAAACGAGATTTTTTTCCCTCATTTTTCTCATTGTAGATGTCATCTCTCACATTTATATCA
GTGAGGTTTGAAATTCTGTGTAGCAGTTACTCAGCACATATGAGAGGGCAGCGAATGAATGAGATTTGTCATGTGCTAATAAAAGCTGAA
TTTTTGTAATCTAAAATGATGTATTTTCTACTATTGCTGTTAATTTGCATTGTTAAAAATTCTTAAAGTTTAATATGTTATGTTCAGTCA
TTGAAAGCGACCACTCATTTTTTTCTTAAAGTTGATGCCTTTTCTGCTGTGCTAGAGTCAGTATTTTGCTTCTGGCAGGAGAGCTGCAAA
CTGTGTATCCTCAAACAGATGCAAAAAGTAGTGCTTTGCAAAACGTTTGTTTTCTGTTTATCTCAGATTAACATCCTTTAATACAAGTTT
CTTAAGTGTAACTTGTATTTCTGAAAATGCTTAAAATTATTTTATATTTCCCTTTGGGAATTTTTCTCTATTTCCAGCACGCTGATTTGA
TTTAAAAATGTAATAAGACCAAGAGTTGGAGTAAAGGGATATTCATTCCATGTTAAAAGTGGCTTCATAGCTACTGACAAATGTCTGAAC
TATTGTCGTGCCCTTCAAAACTGGAGTTTTCTAAAATAATCTTATTTTTATACTTGTATGTTCCAGCAATTTAAGATATATACCATTGAA

>351_351_12_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000361802_BACE2_chr21_42598193_ENST00000347667_length(amino acids)=784AA_BP=420
MACLMAAFSVGTAMNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSLPRRAAVNIEFRDLSYSVPEGP
WWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMV
SAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSII
CTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGD
AEVNPFLWHRPSEEVKQTKRLKGLRKDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSLQILVDTGSSNFAVAGTPHSYIDTYFDTER
SSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANI
PNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQK
VFDAVVEAVARASLLYIQPMMGAGLNYECYRFGISPSTNALVIGATVMEGFYVIFDRAQKRVGFAASPCAEIAGAAVSEISGPFSTEDVA

--------------------------------------------------------------
>351_351_13_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000398437_BACE2_chr21_42598193_ENST00000328735_length(transcript)=3895nt_BP=1846nt
TTCTTTCCAAGGGTCTCTGGGTGAGGCCCGTGACCTTCCCAAGCCTCTCCCTGTCTTGTGAAACCTGGGCGTGATATACCTCCCTTTTAG
GGCTGCTGCGATCATTTAGGCAGATTAAACCTCATAAGTGGTTTCCCATACAAGAAAGATGCTAGCAGTGCAACAGACAGAACACTTACC
TGCCTGCCCTCCCGCCAGGAGGTGGTCTTCCAACTTTTGCCCGGAGTCTACAGAGGGTGGGCCCTCTCTGCTGGGGCTCCGGGACATGGT
CAGGAGAGGTTGGTCTGTCTGTACCGCCATTCTCTTGGCCAGACTGTGGTGTCTGGTCCCTACTCACACCTTCCTGTCAGAGTATCCAGA
GGCCGCAGAGTATCCACACCCTGGCTGGGTGTACTGGCTACAGATGGCTGTGGCTCCAGGTCACCTGCGTGCCTGGGTGATGAGAAATAA
TGTCACAACAAATATCCCATCTGCATTCTCTGGGACACTGACCCATGAAGAGAAAGCAGTTCTCACAGTTTTTACAGGCACAGCCACAGC
CGTGCATGTACAGGTGGCAGCTTTAGCTTCTGCTAAACTGGAGAGCTCAGTGTTTGTGACAGACTGCGTGTCCTGCAAAATCGAAAATGT
CTGTGATTCAGCTCTTCAGGGAAAAAGGGTGCCGATGTCTGGCCTACAGGGCTCAAGCATTGTCATCATGCCCCCATCCAACCGTCCACT
CGCCAGTGCGGCATCCTGCACGTGGTCAGTCCAAGTCCAGGGAGGGCCCCATCACCTGGGGGTGGTCGCTATCAGTGGCAAAGTCTTGTC
AGCAGCTCATGGGGCAGGAAGGGCCTATGGTTGGGGGTTTCCTGGCGATCCCATGGAGGAAGGATACAAGACCCTCCTGAAAGGAATTTC
CGGGAAGTTCAATAGTGGTGAGTTGGTGGCCATTATGGGTCCTTCCGGGGCCGGGAAGTCCACGCTGATGAACATCCTGGCTGGATACAG
GGAGACGGGCATGAAGGGGGCCGTCCTCATCAACGGCCTGCCCCGGGACCTGCGCTGCTTCCGGAAGGTGTCCTGCTACATCATGCAGGA
TGACATGCTGCTGCCGCATCTCACTGTGCAGGAGGCCATGATGGTGTCGGCACATCTGAAGCTTCAGGAGAAGGATGAAGGCAGAAGGGA
AATGGTCAAGGAGATACTGACAGCGCTGGGCTTGCTGTCTTGCGCCAACACGCGGACCGGGAGCCTGTCAGGTGGTCAGCGCAAGCGCCT
GGCCATCGCGCTGGAGCTGGTGAACAACCCTCCAGTCATGTTCTTCGATGAGCCCACCAGCGGCCTGGACAGCGCCTCCTGCTTCCAGGT
GGTCTCGCTGATGAAAGGGCTCGCTCAAGGGGGTCGCTCCATCATTTGCACCATCCACCAGCCCAGCGCCAAACTCTTCGAGCTGTTCGA
CCAGCTTTACGTCCTGAGTCAAGGACAATGTGTGTACCGGGGAAAAGTCTGCAATCTTGTGCCATATTTGAGGGATTTGGGTCTGAACTG
CCCAACCTACCACAACCCAGCAGATTTTGTCATGGAGGTTGCATCCGGCGAGTACGGTGATCAGAACAGTCGGCTGGTGAGAGCGGTTCG
GGAGGGCATGTGTGACTCAGACCACAAGAGAGACCTCGGGGGTGATGCCGAGGTGAACCCTTTTCTTTGGCACCGGCCCTCTGAAGAGGT
AAAGCAGACAAAACGATTAAAGGGGTTGAGAAAGGACTCCTCGTCCATGGAAGGCTGCCACAGCTTCTCTGCCAGCTGCCTCACGCAGTT
CTGCATCCTCTTCAAGAGGACCTTCCTCAGCATCATGAGGGACTCGCTACAGATTCTCGTTGACACTGGAAGCAGTAACTTTGCCGTGGC
AGGAACCCCGCACTCCTACATAGACACGTACTTTGACACAGAGAGGTCTAGCACATACCGCTCCAAGGGCTTTGACGTCACAGTGAAGTA
CACACAAGGAAGCTGGACGGGCTTCGTTGGGGAAGACCTCGTCACCATCCCCAAAGGCTTCAATACTTCTTTTCTTGTCAACATTGCCAC
TATTTTTGAATCAGAGAATTTCTTTTTGCCTGGGATTAAATGGAATGGAATACTTGGCCTAGCTTATGCCACACTTGCCAAGCCATCAAG
TTCTCTGGAGACCTTCTTCGACTCCCTGGTGACACAAGCAAACATCCCCAACGTTTTCTCCATGCAGATGTGTGGAGCCGGCTTGCCCGT
TGCTGGATCTGGGACCAACGGAGGTAGTCTTGTCTTGGGTGGAATTGAACCAAGTTTGTATAAAGGAGACATCTGGTATACCCCTATTAA
GGAAGAGTGGTACTACCAGATAGAAATTCTGAAATTGGAAATTGGAGGCCAAAGCCTTAATCTGGACTGCAGAGAGTATAACGCAGACAA
GGCCATCGTGGACAGTGGCACCACGCTGCTGCGCCTGCCCCAGAAGGTGTTTGATGCGGTGGTGGAAGCTGTGGCCCGCGCATCTCTGAT
TCCAGAATTCTCTGATGGTTTCTGGACTGGGTCCCAGCTGGCGTGCTGGACGAATTCGGAAACACCTTGGTCTTACTTCCCTAAAATCTC
CATCTACCTGAGAGACGAGAACTCCAGCAGGTCATTCCGTATCACAATCCTGCCTCAGAAATTGCAGGTGCTGCAGTGTCTGAAATTTCC
GGGCCTTTCTCAACAGAGGATGTAGCCAGCAACTGTGTCCCCGCTCAGTCTTTGAGCGAGCCCATTTTGTGGATTGTGTCCTATGCGCTC
ATGAGCGTCTGTGGAGCCATCCTCCTTGTCTTAATCGTCCTGCTGCTGCTGCCGTTCCGGTGTCAGCGTCGCCCCCGTGACCCTGAGGTC
GTCAATGATGAGTCCTCTCTGGTCAGACATCGCTGGAAATGAATAGCCAGGCCTGACCTCAAGCAACCATGAACTCAGCTATTAAGAAAA
TCACATTTCCAGGGCAGCAGCCGGGATCGATGGTGGCGCTTTCTCCTGTGCCCACCCGTCTTCAATCTCTGTTCTGCTCCCAGATGCCTT
CTAGATTCACTGTCTTTTGATTCTTGATTTTCAAGCTTTCAAATCCTCCCTACTTCCAAGAAAAATAATTAAAAAAAAAACTTCATTCTA
AACCAAAACAGAGTGGATTGGGCTGCAGGCTCTATGGGGTTCGTTATGCCAAAGTGTCTACATGTGCCACCAACATAAAACAAAACCAAG
CCTTGGCTCGTTCTCTTCTCTCTTCAATCTCTGGAAAAATAAGTACATATAGTTGATAACCCCTCTTAGCTTACAGGAAGCTTTTTGTAT
TAATTGCCTTTGAGGTTATTTTCCGCCAGACCTCAACCTGGGTCAAAGTGGTACAGGAAGGCTTGCAGTATGATGGCAGGAGAATCAGCC
TGGGGCCTGGGGATGTAACCAAGCTGTACCCTTGAGACCTGGAACCAGAGCCACAGGCCCCTTTTGTGGGTTTCTCTGTGCTCTGAATGG
GAGCCAGAATTCACTAGGAGGTCATCAACCGATGGTCCTCACAAGCCTCTTCTGAAGATGGAAGGCCTTTTGCCCGTTGAGGTAGAGGGG
AAGGAAATCTCCTCTTTTGTACCCAATACTTATGTTGTATTGTTGGTGCGAAAGTAAAAACACTACCTCTTTTGAGACTTTGCCCAGGGT
CCTGTGCCTGGATGGGGGTGCAGGCAGCCTTGACCACGGCTGTTCCCCTCACCCAAAAGAATTATCATCCCAACAGCCAAGACCCAACAG
GTGCTGAACTGTGCATCAACCAGGAAGAGTTCTATCCCCAAGCTGGCCACTATCACATATGCTTACTCTTGCTTAAAATTAATAAATCAT

>351_351_13_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000398437_BACE2_chr21_42598193_ENST00000328735_length(amino acids)=858AA_BP=566
MLAVQQTEHLPACPPARRWSSNFCPESTEGGPSLLGLRDMVRRGWSVCTAILLARLWCLVPTHTFLSEYPEAAEYPHPGWVYWLQMAVAP
GHLRAWVMRNNVTTNIPSAFSGTLTHEEKAVLTVFTGTATAVHVQVAALASAKLESSVFVTDCVSCKIENVCDSALQGKRVPMSGLQGSS
IVIMPPSNRPLASAASCTWSVQVQGGPHHLGVVAISGKVLSAAHGAGRAYGWGFPGDPMEEGYKTLLKGISGKFNSGELVAIMGPSGAGK
STLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRT
GSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNL
VPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGDAEVNPFLWHRPSEEVKQTKRLKGLRKDSSSMEGC
HSFSASCLTQFCILFKRTFLSIMRDSLQILVDTGSSNFAVAGTPHSYIDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKG
FNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSL
YKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVARASLIPEFSDGFWTGSQLACWTNS

--------------------------------------------------------------
>351_351_14_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000398437_BACE2_chr21_42598193_ENST00000330333_length(transcript)=4064nt_BP=1846nt
TTCTTTCCAAGGGTCTCTGGGTGAGGCCCGTGACCTTCCCAAGCCTCTCCCTGTCTTGTGAAACCTGGGCGTGATATACCTCCCTTTTAG
GGCTGCTGCGATCATTTAGGCAGATTAAACCTCATAAGTGGTTTCCCATACAAGAAAGATGCTAGCAGTGCAACAGACAGAACACTTACC
TGCCTGCCCTCCCGCCAGGAGGTGGTCTTCCAACTTTTGCCCGGAGTCTACAGAGGGTGGGCCCTCTCTGCTGGGGCTCCGGGACATGGT
CAGGAGAGGTTGGTCTGTCTGTACCGCCATTCTCTTGGCCAGACTGTGGTGTCTGGTCCCTACTCACACCTTCCTGTCAGAGTATCCAGA
GGCCGCAGAGTATCCACACCCTGGCTGGGTGTACTGGCTACAGATGGCTGTGGCTCCAGGTCACCTGCGTGCCTGGGTGATGAGAAATAA
TGTCACAACAAATATCCCATCTGCATTCTCTGGGACACTGACCCATGAAGAGAAAGCAGTTCTCACAGTTTTTACAGGCACAGCCACAGC
CGTGCATGTACAGGTGGCAGCTTTAGCTTCTGCTAAACTGGAGAGCTCAGTGTTTGTGACAGACTGCGTGTCCTGCAAAATCGAAAATGT
CTGTGATTCAGCTCTTCAGGGAAAAAGGGTGCCGATGTCTGGCCTACAGGGCTCAAGCATTGTCATCATGCCCCCATCCAACCGTCCACT
CGCCAGTGCGGCATCCTGCACGTGGTCAGTCCAAGTCCAGGGAGGGCCCCATCACCTGGGGGTGGTCGCTATCAGTGGCAAAGTCTTGTC
AGCAGCTCATGGGGCAGGAAGGGCCTATGGTTGGGGGTTTCCTGGCGATCCCATGGAGGAAGGATACAAGACCCTCCTGAAAGGAATTTC
CGGGAAGTTCAATAGTGGTGAGTTGGTGGCCATTATGGGTCCTTCCGGGGCCGGGAAGTCCACGCTGATGAACATCCTGGCTGGATACAG
GGAGACGGGCATGAAGGGGGCCGTCCTCATCAACGGCCTGCCCCGGGACCTGCGCTGCTTCCGGAAGGTGTCCTGCTACATCATGCAGGA
TGACATGCTGCTGCCGCATCTCACTGTGCAGGAGGCCATGATGGTGTCGGCACATCTGAAGCTTCAGGAGAAGGATGAAGGCAGAAGGGA
AATGGTCAAGGAGATACTGACAGCGCTGGGCTTGCTGTCTTGCGCCAACACGCGGACCGGGAGCCTGTCAGGTGGTCAGCGCAAGCGCCT
GGCCATCGCGCTGGAGCTGGTGAACAACCCTCCAGTCATGTTCTTCGATGAGCCCACCAGCGGCCTGGACAGCGCCTCCTGCTTCCAGGT
GGTCTCGCTGATGAAAGGGCTCGCTCAAGGGGGTCGCTCCATCATTTGCACCATCCACCAGCCCAGCGCCAAACTCTTCGAGCTGTTCGA
CCAGCTTTACGTCCTGAGTCAAGGACAATGTGTGTACCGGGGAAAAGTCTGCAATCTTGTGCCATATTTGAGGGATTTGGGTCTGAACTG
CCCAACCTACCACAACCCAGCAGATTTTGTCATGGAGGTTGCATCCGGCGAGTACGGTGATCAGAACAGTCGGCTGGTGAGAGCGGTTCG
GGAGGGCATGTGTGACTCAGACCACAAGAGAGACCTCGGGGGTGATGCCGAGGTGAACCCTTTTCTTTGGCACCGGCCCTCTGAAGAGGT
AAAGCAGACAAAACGATTAAAGGGGTTGAGAAAGGACTCCTCGTCCATGGAAGGCTGCCACAGCTTCTCTGCCAGCTGCCTCACGCAGTT
CTGCATCCTCTTCAAGAGGACCTTCCTCAGCATCATGAGGGACTCGCTACAGATTCTCGTTGACACTGGAAGCAGTAACTTTGCCGTGGC
AGGAACCCCGCACTCCTACATAGACACGTACTTTGACACAGAGAGGTCTAGCACATACCGCTCCAAGGGCTTTGACGTCACAGTGAAGTA
CACACAAGGAAGCTGGACGGGCTTCGTTGGGGAAGACCTCGTCACCATCCCCAAAGGCTTCAATACTTCTTTTCTTGTCAACATTGCCAC
TATTTTTGAATCAGAGAATTTCTTTTTGCCTGGGATTAAATGGAATGGAATACTTGGCCTAGCTTATGCCACACTTGCCAAGCCATCAAG
TTCTCTGGAGACCTTCTTCGACTCCCTGGTGACACAAGCAAACATCCCCAACGTTTTCTCCATGCAGATGTGTGGAGCCGGCTTGCCCGT
TGCTGGATCTGGGACCAACGGAGGTAGTCTTGTCTTGGGTGGAATTGAACCAAGTTTGTATAAAGGAGACATCTGGTATACCCCTATTAA
GGAAGAGTGGTACTACCAGATAGAAATTCTGAAATTGGAAATTGGAGGCCAAAGCCTTAATCTGGACTGCAGAGAGTATAACGCAGACAA
GGCCATCGTGGACAGTGGCACCACGCTGCTGCGCCTGCCCCAGAAGGTGTTTGATGCGGTGGTGGAAGCTGTGGCCCGCGCATCTCTGAT
TCCAGAATTCTCTGATGGTTTCTGGACTGGGTCCCAGCTGGCGTGCTGGACGAATTCGGAAACACCTTGGTCTTACTTCCCTAAAATCTC
CATCTACCTGAGAGACGAGAACTCCAGCAGGTCATTCCGTATCACAATCCTGCCTCAGCTTTACATTCAGCCCATGATGGGGGCCGGCCT
GAATTATGAATGTTACCGATTCGGCATTTCCCCATCCACAAATGCGCTGGTGATCGGTGCCACGGTGATGGAGGGCTTCTACGTCATCTT
CGACAGAGCCCAGAAGAGGGTGGGCTTCGCAGCGAGCCCCTGTGCAGAAATTGCAGGTGCTGCAGTGTCTGAAATTTCCGGGCCTTTCTC
AACAGAGGATGTAGCCAGCAACTGTGTCCCCGCTCAGTCTTTGAGCGAGCCCATTTTGTGGATTGTGTCCTATGCGCTCATGAGCGTCTG
TGGAGCCATCCTCCTTGTCTTAATCGTCCTGCTGCTGCTGCCGTTCCGGTGTCAGCGTCGCCCCCGTGACCCTGAGGTCGTCAATGATGA
GTCCTCTCTGGTCAGACATCGCTGGAAATGAATAGCCAGGCCTGACCTCAAGCAACCATGAACTCAGCTATTAAGAAAATCACATTTCCA
GGGCAGCAGCCGGGATCGATGGTGGCGCTTTCTCCTGTGCCCACCCGTCTTCAATCTCTGTTCTGCTCCCAGATGCCTTCTAGATTCACT
GTCTTTTGATTCTTGATTTTCAAGCTTTCAAATCCTCCCTACTTCCAAGAAAAATAATTAAAAAAAAAACTTCATTCTAAACCAAAACAG
AGTGGATTGGGCTGCAGGCTCTATGGGGTTCGTTATGCCAAAGTGTCTACATGTGCCACCAACATAAAACAAAACCAAGCCTTGGCTCGT
TCTCTTCTCTCTTCAATCTCTGGAAAAATAAGTACATATAGTTGATAACCCCTCTTAGCTTACAGGAAGCTTTTTGTATTAATTGCCTTT
GAGGTTATTTTCCGCCAGACCTCAACCTGGGTCAAAGTGGTACAGGAAGGCTTGCAGTATGATGGCAGGAGAATCAGCCTGGGGCCTGGG
GATGTAACCAAGCTGTACCCTTGAGACCTGGAACCAGAGCCACAGGCCCCTTTTGTGGGTTTCTCTGTGCTCTGAATGGGAGCCAGAATT
CACTAGGAGGTCATCAACCGATGGTCCTCACAAGCCTCTTCTGAAGATGGAAGGCCTTTTGCCCGTTGAGGTAGAGGGGAAGGAAATCTC
CTCTTTTGTACCCAATACTTATGTTGTATTGTTGGTGCGAAAGTAAAAACACTACCTCTTTTGAGACTTTGCCCAGGGTCCTGTGCCTGG
ATGGGGGTGCAGGCAGCCTTGACCACGGCTGTTCCCCTCACCCAAAAGAATTATCATCCCAACAGCCAAGACCCAACAGGTGCTGAACTG
TGCATCAACCAGGAAGAGTTCTATCCCCAAGCTGGCCACTATCACATATGCTTACTCTTGCTTAAAATTAATAAATCATGTTTTGATGAG

>351_351_14_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000398437_BACE2_chr21_42598193_ENST00000330333_length(amino acids)=980AA_BP=566
MLAVQQTEHLPACPPARRWSSNFCPESTEGGPSLLGLRDMVRRGWSVCTAILLARLWCLVPTHTFLSEYPEAAEYPHPGWVYWLQMAVAP
GHLRAWVMRNNVTTNIPSAFSGTLTHEEKAVLTVFTGTATAVHVQVAALASAKLESSVFVTDCVSCKIENVCDSALQGKRVPMSGLQGSS
IVIMPPSNRPLASAASCTWSVQVQGGPHHLGVVAISGKVLSAAHGAGRAYGWGFPGDPMEEGYKTLLKGISGKFNSGELVAIMGPSGAGK
STLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRT
GSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNL
VPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGDAEVNPFLWHRPSEEVKQTKRLKGLRKDSSSMEGC
HSFSASCLTQFCILFKRTFLSIMRDSLQILVDTGSSNFAVAGTPHSYIDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKG
FNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSL
YKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVARASLIPEFSDGFWTGSQLACWTNS
ETPWSYFPKISIYLRDENSSRSFRITILPQLYIQPMMGAGLNYECYRFGISPSTNALVIGATVMEGFYVIFDRAQKRVGFAASPCAEIAG

--------------------------------------------------------------
>351_351_15_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000398437_BACE2_chr21_42598193_ENST00000347667_length(transcript)=9835nt_BP=1846nt
TTCTTTCCAAGGGTCTCTGGGTGAGGCCCGTGACCTTCCCAAGCCTCTCCCTGTCTTGTGAAACCTGGGCGTGATATACCTCCCTTTTAG
GGCTGCTGCGATCATTTAGGCAGATTAAACCTCATAAGTGGTTTCCCATACAAGAAAGATGCTAGCAGTGCAACAGACAGAACACTTACC
TGCCTGCCCTCCCGCCAGGAGGTGGTCTTCCAACTTTTGCCCGGAGTCTACAGAGGGTGGGCCCTCTCTGCTGGGGCTCCGGGACATGGT
CAGGAGAGGTTGGTCTGTCTGTACCGCCATTCTCTTGGCCAGACTGTGGTGTCTGGTCCCTACTCACACCTTCCTGTCAGAGTATCCAGA
GGCCGCAGAGTATCCACACCCTGGCTGGGTGTACTGGCTACAGATGGCTGTGGCTCCAGGTCACCTGCGTGCCTGGGTGATGAGAAATAA
TGTCACAACAAATATCCCATCTGCATTCTCTGGGACACTGACCCATGAAGAGAAAGCAGTTCTCACAGTTTTTACAGGCACAGCCACAGC
CGTGCATGTACAGGTGGCAGCTTTAGCTTCTGCTAAACTGGAGAGCTCAGTGTTTGTGACAGACTGCGTGTCCTGCAAAATCGAAAATGT
CTGTGATTCAGCTCTTCAGGGAAAAAGGGTGCCGATGTCTGGCCTACAGGGCTCAAGCATTGTCATCATGCCCCCATCCAACCGTCCACT
CGCCAGTGCGGCATCCTGCACGTGGTCAGTCCAAGTCCAGGGAGGGCCCCATCACCTGGGGGTGGTCGCTATCAGTGGCAAAGTCTTGTC
AGCAGCTCATGGGGCAGGAAGGGCCTATGGTTGGGGGTTTCCTGGCGATCCCATGGAGGAAGGATACAAGACCCTCCTGAAAGGAATTTC
CGGGAAGTTCAATAGTGGTGAGTTGGTGGCCATTATGGGTCCTTCCGGGGCCGGGAAGTCCACGCTGATGAACATCCTGGCTGGATACAG
GGAGACGGGCATGAAGGGGGCCGTCCTCATCAACGGCCTGCCCCGGGACCTGCGCTGCTTCCGGAAGGTGTCCTGCTACATCATGCAGGA
TGACATGCTGCTGCCGCATCTCACTGTGCAGGAGGCCATGATGGTGTCGGCACATCTGAAGCTTCAGGAGAAGGATGAAGGCAGAAGGGA
AATGGTCAAGGAGATACTGACAGCGCTGGGCTTGCTGTCTTGCGCCAACACGCGGACCGGGAGCCTGTCAGGTGGTCAGCGCAAGCGCCT
GGCCATCGCGCTGGAGCTGGTGAACAACCCTCCAGTCATGTTCTTCGATGAGCCCACCAGCGGCCTGGACAGCGCCTCCTGCTTCCAGGT
GGTCTCGCTGATGAAAGGGCTCGCTCAAGGGGGTCGCTCCATCATTTGCACCATCCACCAGCCCAGCGCCAAACTCTTCGAGCTGTTCGA
CCAGCTTTACGTCCTGAGTCAAGGACAATGTGTGTACCGGGGAAAAGTCTGCAATCTTGTGCCATATTTGAGGGATTTGGGTCTGAACTG
CCCAACCTACCACAACCCAGCAGATTTTGTCATGGAGGTTGCATCCGGCGAGTACGGTGATCAGAACAGTCGGCTGGTGAGAGCGGTTCG
GGAGGGCATGTGTGACTCAGACCACAAGAGAGACCTCGGGGGTGATGCCGAGGTGAACCCTTTTCTTTGGCACCGGCCCTCTGAAGAGGT
AAAGCAGACAAAACGATTAAAGGGGTTGAGAAAGGACTCCTCGTCCATGGAAGGCTGCCACAGCTTCTCTGCCAGCTGCCTCACGCAGTT
CTGCATCCTCTTCAAGAGGACCTTCCTCAGCATCATGAGGGACTCGCTACAGATTCTCGTTGACACTGGAAGCAGTAACTTTGCCGTGGC
AGGAACCCCGCACTCCTACATAGACACGTACTTTGACACAGAGAGGTCTAGCACATACCGCTCCAAGGGCTTTGACGTCACAGTGAAGTA
CACACAAGGAAGCTGGACGGGCTTCGTTGGGGAAGACCTCGTCACCATCCCCAAAGGCTTCAATACTTCTTTTCTTGTCAACATTGCCAC
TATTTTTGAATCAGAGAATTTCTTTTTGCCTGGGATTAAATGGAATGGAATACTTGGCCTAGCTTATGCCACACTTGCCAAGCCATCAAG
TTCTCTGGAGACCTTCTTCGACTCCCTGGTGACACAAGCAAACATCCCCAACGTTTTCTCCATGCAGATGTGTGGAGCCGGCTTGCCCGT
TGCTGGATCTGGGACCAACGGAGGTAGTCTTGTCTTGGGTGGAATTGAACCAAGTTTGTATAAAGGAGACATCTGGTATACCCCTATTAA
GGAAGAGTGGTACTACCAGATAGAAATTCTGAAATTGGAAATTGGAGGCCAAAGCCTTAATCTGGACTGCAGAGAGTATAACGCAGACAA
GGCCATCGTGGACAGTGGCACCACGCTGCTGCGCCTGCCCCAGAAGGTGTTTGATGCGGTGGTGGAAGCTGTGGCCCGCGCATCTCTGCT
TTACATTCAGCCCATGATGGGGGCCGGCCTGAATTATGAATGTTACCGATTCGGCATTTCCCCATCCACAAATGCGCTGGTGATCGGTGC
CACGGTGATGGAGGGCTTCTACGTCATCTTCGACAGAGCCCAGAAGAGGGTGGGCTTCGCAGCGAGCCCCTGTGCAGAAATTGCAGGTGC
TGCAGTGTCTGAAATTTCCGGGCCTTTCTCAACAGAGGATGTAGCCAGCAACTGTGTCCCCGCTCAGTCTTTGAGCGAGCCCATTTTGTG
GATTGTGTCCTATGCGCTCATGAGCGTCTGTGGAGCCATCCTCCTTGTCTTAATCGTCCTGCTGCTGCTGCCGTTCCGGTGTCAGCGTCG
CCCCCGTGACCCTGAGGTCGTCAATGATGAGTCCTCTCTGGTCAGACATCGCTGGAAATGAATAGCCAGGCCTGACCTCAAGCAACCATG
AACTCAGCTATTAAGAAAATCACATTTCCAGGGCAGCAGCCGGGATCGATGGTGGCGCTTTCTCCTGTGCCCACCCGTCTTCAATCTCTG
TTCTGCTCCCAGATGCCTTCTAGATTCACTGTCTTTTGATTCTTGATTTTCAAGCTTTCAAATCCTCCCTACTTCCAAGAAAAATAATTA
AAAAAAAAACTTCATTCTAAACCAAAACAGAGTGGATTGGGCTGCAGGCTCTATGGGGTTCGTTATGCCAAAGTGTCTACATGTGCCACC
AACATAAAACAAAACCAAGCCTTGGCTCGTTCTCTTCTCTCTTCAATCTCTGGAAAAATAAGTACATATAGTTGATAACCCCTCTTAGCT
TACAGGAAGCTTTTTGTATTAATTGCCTTTGAGGTTATTTTCCGCCAGACCTCAACCTGGGTCAAAGTGGTACAGGAAGGCTTGCAGTAT
GATGGCAGGAGAATCAGCCTGGGGCCTGGGGATGTAACCAAGCTGTACCCTTGAGACCTGGAACCAGAGCCACAGGCCCCTTTTGTGGGT
TTCTCTGTGCTCTGAATGGGAGCCAGAATTCACTAGGAGGTCATCAACCGATGGTCCTCACAAGCCTCTTCTGAAGATGGAAGGCCTTTT
GCCCGTTGAGGTAGAGGGGAAGGAAATCTCCTCTTTTGTACCCAATACTTATGTTGTATTGTTGGTGCGAAAGTAAAAACACTACCTCTT
TTGAGACTTTGCCCAGGGTCCTGTGCCTGGATGGGGGTGCAGGCAGCCTTGACCACGGCTGTTCCCCTCACCCAAAAGAATTATCATCCC
AACAGCCAAGACCCAACAGGTGCTGAACTGTGCATCAACCAGGAAGAGTTCTATCCCCAAGCTGGCCACTATCACATATGCTTACTCTTG
CTTAAAATTAATAAATCATGTTTTGATGAGAAAAAACTATTCTATTTCACTAGCTTAGTTGTCTCTTTTTCCAAATCTTCTCTGGAAGTA
GGTTGGCTATTACCCTGTTGGGAAACAGGGAAATGGCCTGATGCCCCTATTTCTGACCAGCTGTCAGGGAAGGAAGATGCAAGATGTGCA
GAAGACACAAGGTAACGTCTACTTATCCCCGTGCTTCGAAACCGTGTGTTTCCCTTTGCAGAACTGGTTAGCCTCAAGCATACCCATCCA
ATCAGCTTAAATTGTTCAGCAGTTGACCTCTGTGCTTCTTCCTTTGGGGGTGTTTAATCTTTGGTAACAGTTGTGCAGTGGTAGCCTTAT
TTCGGGGGGCAGTCCCTACTTTCTGTCACTTATCGAGGCCTTTGCCAAAGAAAAGTGGAAGCCGTTTCCTTGACATAGCCTTATATGACC
TGATGTCATTAGGAGAAGAGTTAAAAGACAGTATCCCCTCTCTCCTGCTTGTGTGCCAAGTTCAGTGTTCCCTTTGCATTTTTTTGGGGT
GGGTTGGCTATATTACAGAATTCCACCAAAAGTGCTAAGTGTCCCCTCCTGCAGAAGTATCGTTTGTATTCACAGTAGGCTACGTGTGGA
TGTTTCAGCCATCTGCTCTGCTCCCTGGGTCCCCGGGTCACCACCATACTGAGAAATATAGGACTCTGCCAAAGAGACGTGGAGGCCACG
TCGGCTTGTCATGGTGTCCTGGAAGACTCTCCAGCAGCCAGAAGAACCTTCTGTGCTGTTTTCACTAGAGAAGATTTGAGTTGCAGCCTC
TTGGAAAGAACATGACGGCACGGAACGGGAGGAGGGGGCTCTTGTATCAGGGCCCGTTGTCACATCCGCTCTCAGCTTGTTGAAAACTCA
TAATCTCAGAATGCATTTCACACGGAGAGATGTCTGGAAGTCCAATTCTCATCCCATTGGCTTTTTCCGTGGTTGCTGTTTTGTGGGCCG
CTTTGCACAGGAGTGAAGCCAACACCCCTAGATTGTGCCTTCACCCTTGCTGTGAAAAATTCAAAGCCCTGAAATAAGAGGAGGGAATCG
CAGACATGCCCTGATTAGTTTTCCTGCTTATTTCTTCATACAGGCATCTTCTGTTCCGTTGTATTGTGTTAGGTTTCAGAGGCGGGGAGC
TTCCTCCTGCAGCAGATGAACAGGCATAGTTCTTAAAATACAGGAAAGTAACAAGTGAGGTTTCCAGGTAGAGTAGGTGAATGAAGTTTG
CCGTCATGCTCTGTATTTCATATCAGATTTCTTTATCTTTTCATATCGCATGTCATTGGATGTGACATTTTGATGAAAATACTGAAACTA
CAAAAGCATAACTTCGCAACAAGAATGAGATAGACAATTGAATGTGGGACATTTTTCTGGCATGTCTTGCTGCTGAGAATCGGACTTCCA
GTCAAAACCCTGTTAGTGACACCCACCTCCTCCAGTTATGCAAATTGATGCTTAGCTTGGCAAGCTTTCAAGGAGGTTTGCTTGGAACAG
GAAAGGAATTAACAACCCTTTGAGGGTGTCATTTTTACCTTGTAATACACTGTGGAAAATTCTGGAAGACGGTCCTTGCCTGAAAAGGTG
CAACTTAGCATTAGGTTGTTATCAGAAACCTTGTCAAGTCTGATGGGAAATGAATAGATGCTGCTTTATTTCCTTGATAACTTCTTTGGA
AGTCTGAAATAAATCCTGCCTTCAGTAACTGAAACCATTTATTAAAAATAGCAAGAAACAAGATGGGGACCAATTCTATTTTTATTCTTG
GGAATTTGAAAGAGCCACAAGTGATTGGTGTCCGATCTCCCAGCATATACTGTACACTATTTTGTATTTCTCCTGAACCAAAACCAAGTA
CTTAGCACTCAAGAAACAGATGCCCTGTGTGTGACCGAGGGGAGTGTTTTTCCACAACAGGTTCCACTTCTGAACACTTGGAAGGACCTT
GCCTGATTCATGGTGAAACACAGAGGTTTTGGTTGGAGATAAATTTGGGGTCAGTTACTGTTCAAAATTGTGAAAGTAGTTCCCAGGAAG
ACAGCATTAGTGACTCCGCAGTGCTTTGGGTAATAGATTTTGAAAAGCAATTGTGAGTTGGGGATTCCATCATTTCATTTAAGAGGTGAA
GAGGGATTTAATTATTTAATACGCCGGGTGCAAACTTGTTAAATTCCTCTTTCCCTGTCCCTGCTTGGTGGAGCTGCCACGTGTGGTTCA
GTTCTAAGTTCTGGACTAGTGCCACTCGATATCATTGGGAATAAATCGTTGTTCAACAGTCTGTTCCACAAACAACAGTAATTGAATTTC
ACAGACTTTATCCTGATTAGTGGAAATCAAATAATGGAGTGGAATCCCCATGTGTTTTCTCTTGCACAAACTTATTAGACTTGATTAGAA
AACTGTTTGGAGGAAAAACTTGCCAGTAAGTTTTTTGGTTGTTGTTTTGTTTTTTTTGAAAAACGACGCAACACCATAAAGTGTAAAATT
AGGGGTTCTGGCCAAGAGAGGTACTAGATTTTTTTAATGCCGAGAAAAGTCCATGCCACAGAAGTTATTGTGTATGTCTCTAGGGAGCTT
TAAGAATTTCACGTTTGAACTTTACAGCTGTTTACCAATTAAATGGCAAGCTGGAAAAATACATTTTGAGAGGGGTAGAAAGAATAAGAA
TATAATTAAAAGTATGCTAACAAAATAAGCAGTACATATTTTTTTAGAAAATGCAGTTTAGGCCAGGCACGGTAGCTCGTGCCTGTAATC
CCAGCACTTTGGGAGGCCGAGGCAGGTGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGGACAACATGGTGAAACCCCGTCTCTACT
AAAAATACAAAAAATTAGCCAACGATGGTGATGCCTGTCTGTAATCCCAGCTACTCTGGAGGCTGAGGCAGGAGAATCGCTTGAACCGGG
GAGGCAGAGGTTGTAGTGAGCCAAGATTGCGCCACTGCACTCCAGCCTGGGCAACAGAGCAAGACTCCGTCTCAAAAAAGGAAAGAAAAT
GCAGTTTCATTCCAGCCATCCTTAGATTTCTTTTCCCCTTAAAGTGGCTGAATCCATTGGAGATGTGATTTATTTTGCAGATCCACCAAT
TCCAAACTTCAGGAATATTCAAGCGGGAGTCATGTGTAAGTGACAGCTTTGACAAAGAGAGACTGTGGCTGGGTGGCCCGGGTGTTGCCC
ACGCGGAGCAAGGATTGGTTCATTCAACGGATGGAGAGTACAGGATGGCTGGGACCTGGGAAGTTCCAGAATCTGAAAAGAGGGCAGGGC
AAGAAGGAGCCAGAAGAGAGGTCCCACCCCTCAGTTGGCAGTGGGGCACGGAGGTCCGCATCAGCCAAGAACGTCCCCAGGATGCCGTGG
GCACCTCATTTCACCCCACGTTTTTGGCACAGTCTACTTTTTAGGTATTTTGTAAAGGAACTTCTCAGGATTGATTATTTGCCAGAGGAA
CAATTAGGCCAAGAGAAACTTGCTTGACAGCCATGTGTAAAACACGTCTGTCCTAATCAAACTAGAGATGCCTCAAGGCCCACGCAGGAC
ACAGGCAGGTTCAAGGTCATGCACCTGGAAATTTGTAGGGGAGGGTCAAGCAACTGAGGCCAAAGGGGGCCGGTAAAGTGGCTTCTGGGG
TCTGAGCATCTGGAAGGCTCCTGGCAGCAGTTACCTGACAGTGTCGTTGAGGGGCACGGCAGCTGGGCCCTCACCGTTTCCGCCAGCTCT
GCTGAGCCAGCCCAGCCCATGCATTCCGAACATCCGACAGCTTCTTTCTCCAGAATGTCTTCTGTCAGAGACTTCCAGGAAAGGAGCTCC
CTCCTGTCTCACTGCTGTCAGCGTGGGAGCCCTGCTCCCCAGGCTCCACGTCCCCGGAAGGTCCATCTTGTCCTGGAGCACACCCAGCCC
CATTCAGGGTCAGTGCAGGAGGGAACAGGGAATCTGCATTTCAGTAAGCTCCCCAGGTGAGGCTGCAGAGCAGAAACCACGGCTTTCAGA
CGTGAGCAGGCTCCCTGGGCTCTTGGTGTCACCCTGTTAGCCACATCTGCGGAATGTGGAAGGCAGAACATAGCCACGCTGCTTAGTGCT
GCCAGCGAACCTCAGGTTGCATCAGTGGCTGGAATCTATCACAGCTGTTGGGGATACGTAACTCCCAGCAATAAATCCAGTATTTTCTTC
CCTGCCCTGAGCTTCCTCTGGGTTTCTTATCAGCAGCTATTACACACAGATGTCCAGTGCTTCTAAACTAAATTGTACTGTGTAACTTTT
ACATCACACTTGTGTGCTTAAAAAGCACACCGTGGGTAGTGACTGGGCCAAGAGACATCACAAAGCTTCCTGATAAATTTGAATCCAGCC
ACGGCAAGAGCGACGTGCGGGTACCTGGTCCCTGATGCTTGGGTGCCCCGTTGAGCCTCGGGTACTTCTTGGACACTATTGTGAGAGCAG
CCATCCTGGTGTCTCTGCCAGCATCTTGGGGAACGCTGTGATGGTAAAATATCTGTCTCTCCTCTGGGAATCAGGGCAGCCCTGAGAAGT
GAGCAGTTCCCTTTACAGATGGATAATTGTTTGTGTAAGACCAACCAGATAAAGTCCAAACTGTGTAGAACACACGTGTGCCTCACACAT
AGCCATCTGAGTAAAATATTTTTTCCAATGTAGATTTATAATTAGAAATGACAGATTTATAATATAGACTTCAGTAAGTTGGGCACAGCT
GTCACTTTCGTGGTATCAATAAAAGGCTAGAAACCTTGGGTGTCCTTGGCAACCTAGCCTTTGACATTGATGTTTTTCCATAGGATTTTC
TTCATTTGGGTTGGAATAAAAATGCATTTTTATTCACAAGGCACAGACAGATAAGAATATCATAAGCAGGGAAGTGTCTCCAAAGGTCAG
GACATATGTTTTTCTGTTGAGTGCTATATGTGGAGGTCATTGCAAGTTCCCTGATATGAGTATGGTTTCGCTTGCTACATTGTGCCTATT
AAAGTAAAATTTTACACAAGCCTCGCATTTCTAAGATTAGTGTTCCTGAATGAAATGTTAAGAAAACATTAAAAGATTATCTCTTTTTAA
GATGGAGGAAAAAAAGTGAACAAAGCTAATTAATCTATCATGAAAATTGCACAAAATAACATTTCTTAACAAATTTAATACAATTTTGTG
TTCTTTGTTGCTAGTGGTATAAAACGAGATTTTTTTCCCTCATTTTTCTCATTGTAGATGTCATCTCTCACATTTATATCAGTGAGGTTT
GAAATTCTGTGTAGCAGTTACTCAGCACATATGAGAGGGCAGCGAATGAATGAGATTTGTCATGTGCTAATAAAAGCTGAATTTTTGTAA
TCTAAAATGATGTATTTTCTACTATTGCTGTTAATTTGCATTGTTAAAAATTCTTAAAGTTTAATATGTTATGTTCAGTCATTGAAAGCG
ACCACTCATTTTTTTCTTAAAGTTGATGCCTTTTCTGCTGTGCTAGAGTCAGTATTTTGCTTCTGGCAGGAGAGCTGCAAACTGTGTATC
CTCAAACAGATGCAAAAAGTAGTGCTTTGCAAAACGTTTGTTTTCTGTTTATCTCAGATTAACATCCTTTAATACAAGTTTCTTAAGTGT
AACTTGTATTTCTGAAAATGCTTAAAATTATTTTATATTTCCCTTTGGGAATTTTTCTCTATTTCCAGCACGCTGATTTGATTTAAAAAT
GTAATAAGACCAAGAGTTGGAGTAAAGGGATATTCATTCCATGTTAAAAGTGGCTTCATAGCTACTGACAAATGTCTGAACTATTGTCGT
GCCCTTCAAAACTGGAGTTTTCTAAAATAATCTTATTTTTATACTTGTATGTTCCAGCAATTTAAGATATATACCATTGAAAGGGAAATA

>351_351_15_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000398437_BACE2_chr21_42598193_ENST00000347667_length(amino acids)=930AA_BP=566
MLAVQQTEHLPACPPARRWSSNFCPESTEGGPSLLGLRDMVRRGWSVCTAILLARLWCLVPTHTFLSEYPEAAEYPHPGWVYWLQMAVAP
GHLRAWVMRNNVTTNIPSAFSGTLTHEEKAVLTVFTGTATAVHVQVAALASAKLESSVFVTDCVSCKIENVCDSALQGKRVPMSGLQGSS
IVIMPPSNRPLASAASCTWSVQVQGGPHHLGVVAISGKVLSAAHGAGRAYGWGFPGDPMEEGYKTLLKGISGKFNSGELVAIMGPSGAGK
STLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRT
GSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNL
VPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGDAEVNPFLWHRPSEEVKQTKRLKGLRKDSSSMEGC
HSFSASCLTQFCILFKRTFLSIMRDSLQILVDTGSSNFAVAGTPHSYIDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDLVTIPKG
FNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAGLPVAGSGTNGGSLVLGGIEPSL
YKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVARASLLYIQPMMGAGLNYECYRFGI
SPSTNALVIGATVMEGFYVIFDRAQKRVGFAASPCAEIAGAAVSEISGPFSTEDVASNCVPAQSLSEPILWIVSYALMSVCGAILLVLIV

--------------------------------------------------------------
>351_351_16_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000398449_BACE2_chr21_42598193_ENST00000328735_length(transcript)=3418nt_BP=1369nt
GAGCCGGAGCCGGATCCCAGCCGGAGCCCAAGCGCAGCCCGCACCCCGCGCAGCGGCTGAGCCGGGAGCCAGCGCAGCCTCGGCCCCGCA
GCTCAAGCCTCGTCCCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCCCCGGGGCATGGCCTGTCTGATGGCCGCTTTCTCGGTCGGCAC
CGCCATGAATGCCAGCAGTTACTCTGCAGAGATGACGGAGCCCAAGTCGGTGTGTGTCTCGGTGGATGAGGTGGTGTCCAGCAACATGGA
GGCCACTGAGACGGACCTGCTGAATGGACATCTGAAAAAAGTAGATAATAACCTCACGGAAGCCCAGCGCTTCTCCTCCTTGCCTCGGAG
GGCAGCTGTGAACATTGAATTCAGGGACCTTTCCTATTCGGTTCCTGAAGGACCCTGGTGGAGGAAGAAAGGATACAAGACCCTCCTGAA
AGGAATTTCCGGGAAGTTCAATAGTGGTGAGTTGGTGGCCATTATGGGTCCTTCCGGGGCCGGGAAGTCCACGCTGATGAACATCCTGGC
TGGATACAGGGAGACGGGCATGAAGGGGGCCGTCCTCATCAACGGCCTGCCCCGGGACCTGCGCTGCTTCCGGAAGGTGTCCTGCTACAT
CATGCAGGATGACATGCTGCTGCCGCATCTCACTGTGCAGGAGGCCATGATGGTGTCGGCACATCTGAAGCTTCAGGAGAAGGATGAAGG
CAGAAGGGAAATGGTCAAGGAGATACTGACAGCGCTGGGCTTGCTGTCTTGCGCCAACACGCGGACCGGGAGCCTGTCAGGTGGTCAGCG
CAAGCGCCTGGCCATCGCGCTGGAGCTGGTGAACAACCCTCCAGTCATGTTCTTCGATGAGCCCACCAGCGGCCTGGACAGCGCCTCCTG
CTTCCAGGTGGTCTCGCTGATGAAAGGGCTCGCTCAAGGGGGTCGCTCCATCATTTGCACCATCCACCAGCCCAGCGCCAAACTCTTCGA
GCTGTTCGACCAGCTTTACGTCCTGAGTCAAGGACAATGTGTGTACCGGGGAAAAGTCTGCAATCTTGTGCCATATTTGAGGGATTTGGG
TCTGAACTGCCCAACCTACCACAACCCAGCAGATTTTGTCATGGAGGTTGCATCCGGCGAGTACGGTGATCAGAACAGTCGGCTGGTGAG
AGCGGTTCGGGAGGGCATGTGTGACTCAGACCACAAGAGAGACCTCGGGGGTGATGCCGAGGTGAACCCTTTTCTTTGGCACCGGCCCTC
TGAAGAGGACTCCTCGTCCATGGAAGGCTGCCACAGCTTCTCTGCCAGCTGCCTCACGCAGTTCTGCATCCTCTTCAAGAGGACCTTCCT
CAGCATCATGAGGGACTCGCTACAGATTCTCGTTGACACTGGAAGCAGTAACTTTGCCGTGGCAGGAACCCCGCACTCCTACATAGACAC
GTACTTTGACACAGAGAGGTCTAGCACATACCGCTCCAAGGGCTTTGACGTCACAGTGAAGTACACACAAGGAAGCTGGACGGGCTTCGT
TGGGGAAGACCTCGTCACCATCCCCAAAGGCTTCAATACTTCTTTTCTTGTCAACATTGCCACTATTTTTGAATCAGAGAATTTCTTTTT
GCCTGGGATTAAATGGAATGGAATACTTGGCCTAGCTTATGCCACACTTGCCAAGCCATCAAGTTCTCTGGAGACCTTCTTCGACTCCCT
GGTGACACAAGCAAACATCCCCAACGTTTTCTCCATGCAGATGTGTGGAGCCGGCTTGCCCGTTGCTGGATCTGGGACCAACGGAGGTAG
TCTTGTCTTGGGTGGAATTGAACCAAGTTTGTATAAAGGAGACATCTGGTATACCCCTATTAAGGAAGAGTGGTACTACCAGATAGAAAT
TCTGAAATTGGAAATTGGAGGCCAAAGCCTTAATCTGGACTGCAGAGAGTATAACGCAGACAAGGCCATCGTGGACAGTGGCACCACGCT
GCTGCGCCTGCCCCAGAAGGTGTTTGATGCGGTGGTGGAAGCTGTGGCCCGCGCATCTCTGATTCCAGAATTCTCTGATGGTTTCTGGAC
TGGGTCCCAGCTGGCGTGCTGGACGAATTCGGAAACACCTTGGTCTTACTTCCCTAAAATCTCCATCTACCTGAGAGACGAGAACTCCAG
CAGGTCATTCCGTATCACAATCCTGCCTCAGAAATTGCAGGTGCTGCAGTGTCTGAAATTTCCGGGCCTTTCTCAACAGAGGATGTAGCC
AGCAACTGTGTCCCCGCTCAGTCTTTGAGCGAGCCCATTTTGTGGATTGTGTCCTATGCGCTCATGAGCGTCTGTGGAGCCATCCTCCTT
GTCTTAATCGTCCTGCTGCTGCTGCCGTTCCGGTGTCAGCGTCGCCCCCGTGACCCTGAGGTCGTCAATGATGAGTCCTCTCTGGTCAGA
CATCGCTGGAAATGAATAGCCAGGCCTGACCTCAAGCAACCATGAACTCAGCTATTAAGAAAATCACATTTCCAGGGCAGCAGCCGGGAT
CGATGGTGGCGCTTTCTCCTGTGCCCACCCGTCTTCAATCTCTGTTCTGCTCCCAGATGCCTTCTAGATTCACTGTCTTTTGATTCTTGA
TTTTCAAGCTTTCAAATCCTCCCTACTTCCAAGAAAAATAATTAAAAAAAAAACTTCATTCTAAACCAAAACAGAGTGGATTGGGCTGCA
GGCTCTATGGGGTTCGTTATGCCAAAGTGTCTACATGTGCCACCAACATAAAACAAAACCAAGCCTTGGCTCGTTCTCTTCTCTCTTCAA
TCTCTGGAAAAATAAGTACATATAGTTGATAACCCCTCTTAGCTTACAGGAAGCTTTTTGTATTAATTGCCTTTGAGGTTATTTTCCGCC
AGACCTCAACCTGGGTCAAAGTGGTACAGGAAGGCTTGCAGTATGATGGCAGGAGAATCAGCCTGGGGCCTGGGGATGTAACCAAGCTGT
ACCCTTGAGACCTGGAACCAGAGCCACAGGCCCCTTTTGTGGGTTTCTCTGTGCTCTGAATGGGAGCCAGAATTCACTAGGAGGTCATCA
ACCGATGGTCCTCACAAGCCTCTTCTGAAGATGGAAGGCCTTTTGCCCGTTGAGGTAGAGGGGAAGGAAATCTCCTCTTTTGTACCCAAT
ACTTATGTTGTATTGTTGGTGCGAAAGTAAAAACACTACCTCTTTTGAGACTTTGCCCAGGGTCCTGTGCCTGGATGGGGGTGCAGGCAG
CCTTGACCACGGCTGTTCCCCTCACCCAAAAGAATTATCATCCCAACAGCCAAGACCCAACAGGTGCTGAACTGTGCATCAACCAGGAAG

>351_351_16_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000398449_BACE2_chr21_42598193_ENST00000328735_length(amino acids)=700AA_BP=408
MACLMAAFSVGTAMNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSLPRRAAVNIEFRDLSYSVPEGP
WWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMV
SAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSII
CTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGD
AEVNPFLWHRPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSLQILVDTGSSNFAVAGTPHSYIDTYFDTERSSTYRSKGFDVT
VKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAG
LPVAGSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVARA

--------------------------------------------------------------
>351_351_17_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000398449_BACE2_chr21_42598193_ENST00000330333_length(transcript)=3587nt_BP=1369nt
GAGCCGGAGCCGGATCCCAGCCGGAGCCCAAGCGCAGCCCGCACCCCGCGCAGCGGCTGAGCCGGGAGCCAGCGCAGCCTCGGCCCCGCA
GCTCAAGCCTCGTCCCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCCCCGGGGCATGGCCTGTCTGATGGCCGCTTTCTCGGTCGGCAC
CGCCATGAATGCCAGCAGTTACTCTGCAGAGATGACGGAGCCCAAGTCGGTGTGTGTCTCGGTGGATGAGGTGGTGTCCAGCAACATGGA
GGCCACTGAGACGGACCTGCTGAATGGACATCTGAAAAAAGTAGATAATAACCTCACGGAAGCCCAGCGCTTCTCCTCCTTGCCTCGGAG
GGCAGCTGTGAACATTGAATTCAGGGACCTTTCCTATTCGGTTCCTGAAGGACCCTGGTGGAGGAAGAAAGGATACAAGACCCTCCTGAA
AGGAATTTCCGGGAAGTTCAATAGTGGTGAGTTGGTGGCCATTATGGGTCCTTCCGGGGCCGGGAAGTCCACGCTGATGAACATCCTGGC
TGGATACAGGGAGACGGGCATGAAGGGGGCCGTCCTCATCAACGGCCTGCCCCGGGACCTGCGCTGCTTCCGGAAGGTGTCCTGCTACAT
CATGCAGGATGACATGCTGCTGCCGCATCTCACTGTGCAGGAGGCCATGATGGTGTCGGCACATCTGAAGCTTCAGGAGAAGGATGAAGG
CAGAAGGGAAATGGTCAAGGAGATACTGACAGCGCTGGGCTTGCTGTCTTGCGCCAACACGCGGACCGGGAGCCTGTCAGGTGGTCAGCG
CAAGCGCCTGGCCATCGCGCTGGAGCTGGTGAACAACCCTCCAGTCATGTTCTTCGATGAGCCCACCAGCGGCCTGGACAGCGCCTCCTG
CTTCCAGGTGGTCTCGCTGATGAAAGGGCTCGCTCAAGGGGGTCGCTCCATCATTTGCACCATCCACCAGCCCAGCGCCAAACTCTTCGA
GCTGTTCGACCAGCTTTACGTCCTGAGTCAAGGACAATGTGTGTACCGGGGAAAAGTCTGCAATCTTGTGCCATATTTGAGGGATTTGGG
TCTGAACTGCCCAACCTACCACAACCCAGCAGATTTTGTCATGGAGGTTGCATCCGGCGAGTACGGTGATCAGAACAGTCGGCTGGTGAG
AGCGGTTCGGGAGGGCATGTGTGACTCAGACCACAAGAGAGACCTCGGGGGTGATGCCGAGGTGAACCCTTTTCTTTGGCACCGGCCCTC
TGAAGAGGACTCCTCGTCCATGGAAGGCTGCCACAGCTTCTCTGCCAGCTGCCTCACGCAGTTCTGCATCCTCTTCAAGAGGACCTTCCT
CAGCATCATGAGGGACTCGCTACAGATTCTCGTTGACACTGGAAGCAGTAACTTTGCCGTGGCAGGAACCCCGCACTCCTACATAGACAC
GTACTTTGACACAGAGAGGTCTAGCACATACCGCTCCAAGGGCTTTGACGTCACAGTGAAGTACACACAAGGAAGCTGGACGGGCTTCGT
TGGGGAAGACCTCGTCACCATCCCCAAAGGCTTCAATACTTCTTTTCTTGTCAACATTGCCACTATTTTTGAATCAGAGAATTTCTTTTT
GCCTGGGATTAAATGGAATGGAATACTTGGCCTAGCTTATGCCACACTTGCCAAGCCATCAAGTTCTCTGGAGACCTTCTTCGACTCCCT
GGTGACACAAGCAAACATCCCCAACGTTTTCTCCATGCAGATGTGTGGAGCCGGCTTGCCCGTTGCTGGATCTGGGACCAACGGAGGTAG
TCTTGTCTTGGGTGGAATTGAACCAAGTTTGTATAAAGGAGACATCTGGTATACCCCTATTAAGGAAGAGTGGTACTACCAGATAGAAAT
TCTGAAATTGGAAATTGGAGGCCAAAGCCTTAATCTGGACTGCAGAGAGTATAACGCAGACAAGGCCATCGTGGACAGTGGCACCACGCT
GCTGCGCCTGCCCCAGAAGGTGTTTGATGCGGTGGTGGAAGCTGTGGCCCGCGCATCTCTGATTCCAGAATTCTCTGATGGTTTCTGGAC
TGGGTCCCAGCTGGCGTGCTGGACGAATTCGGAAACACCTTGGTCTTACTTCCCTAAAATCTCCATCTACCTGAGAGACGAGAACTCCAG
CAGGTCATTCCGTATCACAATCCTGCCTCAGCTTTACATTCAGCCCATGATGGGGGCCGGCCTGAATTATGAATGTTACCGATTCGGCAT
TTCCCCATCCACAAATGCGCTGGTGATCGGTGCCACGGTGATGGAGGGCTTCTACGTCATCTTCGACAGAGCCCAGAAGAGGGTGGGCTT
CGCAGCGAGCCCCTGTGCAGAAATTGCAGGTGCTGCAGTGTCTGAAATTTCCGGGCCTTTCTCAACAGAGGATGTAGCCAGCAACTGTGT
CCCCGCTCAGTCTTTGAGCGAGCCCATTTTGTGGATTGTGTCCTATGCGCTCATGAGCGTCTGTGGAGCCATCCTCCTTGTCTTAATCGT
CCTGCTGCTGCTGCCGTTCCGGTGTCAGCGTCGCCCCCGTGACCCTGAGGTCGTCAATGATGAGTCCTCTCTGGTCAGACATCGCTGGAA
ATGAATAGCCAGGCCTGACCTCAAGCAACCATGAACTCAGCTATTAAGAAAATCACATTTCCAGGGCAGCAGCCGGGATCGATGGTGGCG
CTTTCTCCTGTGCCCACCCGTCTTCAATCTCTGTTCTGCTCCCAGATGCCTTCTAGATTCACTGTCTTTTGATTCTTGATTTTCAAGCTT
TCAAATCCTCCCTACTTCCAAGAAAAATAATTAAAAAAAAAACTTCATTCTAAACCAAAACAGAGTGGATTGGGCTGCAGGCTCTATGGG
GTTCGTTATGCCAAAGTGTCTACATGTGCCACCAACATAAAACAAAACCAAGCCTTGGCTCGTTCTCTTCTCTCTTCAATCTCTGGAAAA
ATAAGTACATATAGTTGATAACCCCTCTTAGCTTACAGGAAGCTTTTTGTATTAATTGCCTTTGAGGTTATTTTCCGCCAGACCTCAACC
TGGGTCAAAGTGGTACAGGAAGGCTTGCAGTATGATGGCAGGAGAATCAGCCTGGGGCCTGGGGATGTAACCAAGCTGTACCCTTGAGAC
CTGGAACCAGAGCCACAGGCCCCTTTTGTGGGTTTCTCTGTGCTCTGAATGGGAGCCAGAATTCACTAGGAGGTCATCAACCGATGGTCC
TCACAAGCCTCTTCTGAAGATGGAAGGCCTTTTGCCCGTTGAGGTAGAGGGGAAGGAAATCTCCTCTTTTGTACCCAATACTTATGTTGT
ATTGTTGGTGCGAAAGTAAAAACACTACCTCTTTTGAGACTTTGCCCAGGGTCCTGTGCCTGGATGGGGGTGCAGGCAGCCTTGACCACG
GCTGTTCCCCTCACCCAAAAGAATTATCATCCCAACAGCCAAGACCCAACAGGTGCTGAACTGTGCATCAACCAGGAAGAGTTCTATCCC

>351_351_17_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000398449_BACE2_chr21_42598193_ENST00000330333_length(amino acids)=822AA_BP=408
MACLMAAFSVGTAMNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSLPRRAAVNIEFRDLSYSVPEGP
WWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMV
SAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSII
CTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGD
AEVNPFLWHRPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSLQILVDTGSSNFAVAGTPHSYIDTYFDTERSSTYRSKGFDVT
VKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAG
LPVAGSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVARA
SLIPEFSDGFWTGSQLACWTNSETPWSYFPKISIYLRDENSSRSFRITILPQLYIQPMMGAGLNYECYRFGISPSTNALVIGATVMEGFY
VIFDRAQKRVGFAASPCAEIAGAAVSEISGPFSTEDVASNCVPAQSLSEPILWIVSYALMSVCGAILLVLIVLLLLPFRCQRRPRDPEVV

--------------------------------------------------------------
>351_351_18_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000398449_BACE2_chr21_42598193_ENST00000347667_length(transcript)=9358nt_BP=1369nt
GAGCCGGAGCCGGATCCCAGCCGGAGCCCAAGCGCAGCCCGCACCCCGCGCAGCGGCTGAGCCGGGAGCCAGCGCAGCCTCGGCCCCGCA
GCTCAAGCCTCGTCCCCGCCGCCGCCGCCGCCGCCGCCGCCGCCGCCCCCGGGGCATGGCCTGTCTGATGGCCGCTTTCTCGGTCGGCAC
CGCCATGAATGCCAGCAGTTACTCTGCAGAGATGACGGAGCCCAAGTCGGTGTGTGTCTCGGTGGATGAGGTGGTGTCCAGCAACATGGA
GGCCACTGAGACGGACCTGCTGAATGGACATCTGAAAAAAGTAGATAATAACCTCACGGAAGCCCAGCGCTTCTCCTCCTTGCCTCGGAG
GGCAGCTGTGAACATTGAATTCAGGGACCTTTCCTATTCGGTTCCTGAAGGACCCTGGTGGAGGAAGAAAGGATACAAGACCCTCCTGAA
AGGAATTTCCGGGAAGTTCAATAGTGGTGAGTTGGTGGCCATTATGGGTCCTTCCGGGGCCGGGAAGTCCACGCTGATGAACATCCTGGC
TGGATACAGGGAGACGGGCATGAAGGGGGCCGTCCTCATCAACGGCCTGCCCCGGGACCTGCGCTGCTTCCGGAAGGTGTCCTGCTACAT
CATGCAGGATGACATGCTGCTGCCGCATCTCACTGTGCAGGAGGCCATGATGGTGTCGGCACATCTGAAGCTTCAGGAGAAGGATGAAGG
CAGAAGGGAAATGGTCAAGGAGATACTGACAGCGCTGGGCTTGCTGTCTTGCGCCAACACGCGGACCGGGAGCCTGTCAGGTGGTCAGCG
CAAGCGCCTGGCCATCGCGCTGGAGCTGGTGAACAACCCTCCAGTCATGTTCTTCGATGAGCCCACCAGCGGCCTGGACAGCGCCTCCTG
CTTCCAGGTGGTCTCGCTGATGAAAGGGCTCGCTCAAGGGGGTCGCTCCATCATTTGCACCATCCACCAGCCCAGCGCCAAACTCTTCGA
GCTGTTCGACCAGCTTTACGTCCTGAGTCAAGGACAATGTGTGTACCGGGGAAAAGTCTGCAATCTTGTGCCATATTTGAGGGATTTGGG
TCTGAACTGCCCAACCTACCACAACCCAGCAGATTTTGTCATGGAGGTTGCATCCGGCGAGTACGGTGATCAGAACAGTCGGCTGGTGAG
AGCGGTTCGGGAGGGCATGTGTGACTCAGACCACAAGAGAGACCTCGGGGGTGATGCCGAGGTGAACCCTTTTCTTTGGCACCGGCCCTC
TGAAGAGGACTCCTCGTCCATGGAAGGCTGCCACAGCTTCTCTGCCAGCTGCCTCACGCAGTTCTGCATCCTCTTCAAGAGGACCTTCCT
CAGCATCATGAGGGACTCGCTACAGATTCTCGTTGACACTGGAAGCAGTAACTTTGCCGTGGCAGGAACCCCGCACTCCTACATAGACAC
GTACTTTGACACAGAGAGGTCTAGCACATACCGCTCCAAGGGCTTTGACGTCACAGTGAAGTACACACAAGGAAGCTGGACGGGCTTCGT
TGGGGAAGACCTCGTCACCATCCCCAAAGGCTTCAATACTTCTTTTCTTGTCAACATTGCCACTATTTTTGAATCAGAGAATTTCTTTTT
GCCTGGGATTAAATGGAATGGAATACTTGGCCTAGCTTATGCCACACTTGCCAAGCCATCAAGTTCTCTGGAGACCTTCTTCGACTCCCT
GGTGACACAAGCAAACATCCCCAACGTTTTCTCCATGCAGATGTGTGGAGCCGGCTTGCCCGTTGCTGGATCTGGGACCAACGGAGGTAG
TCTTGTCTTGGGTGGAATTGAACCAAGTTTGTATAAAGGAGACATCTGGTATACCCCTATTAAGGAAGAGTGGTACTACCAGATAGAAAT
TCTGAAATTGGAAATTGGAGGCCAAAGCCTTAATCTGGACTGCAGAGAGTATAACGCAGACAAGGCCATCGTGGACAGTGGCACCACGCT
GCTGCGCCTGCCCCAGAAGGTGTTTGATGCGGTGGTGGAAGCTGTGGCCCGCGCATCTCTGCTTTACATTCAGCCCATGATGGGGGCCGG
CCTGAATTATGAATGTTACCGATTCGGCATTTCCCCATCCACAAATGCGCTGGTGATCGGTGCCACGGTGATGGAGGGCTTCTACGTCAT
CTTCGACAGAGCCCAGAAGAGGGTGGGCTTCGCAGCGAGCCCCTGTGCAGAAATTGCAGGTGCTGCAGTGTCTGAAATTTCCGGGCCTTT
CTCAACAGAGGATGTAGCCAGCAACTGTGTCCCCGCTCAGTCTTTGAGCGAGCCCATTTTGTGGATTGTGTCCTATGCGCTCATGAGCGT
CTGTGGAGCCATCCTCCTTGTCTTAATCGTCCTGCTGCTGCTGCCGTTCCGGTGTCAGCGTCGCCCCCGTGACCCTGAGGTCGTCAATGA
TGAGTCCTCTCTGGTCAGACATCGCTGGAAATGAATAGCCAGGCCTGACCTCAAGCAACCATGAACTCAGCTATTAAGAAAATCACATTT
CCAGGGCAGCAGCCGGGATCGATGGTGGCGCTTTCTCCTGTGCCCACCCGTCTTCAATCTCTGTTCTGCTCCCAGATGCCTTCTAGATTC
ACTGTCTTTTGATTCTTGATTTTCAAGCTTTCAAATCCTCCCTACTTCCAAGAAAAATAATTAAAAAAAAAACTTCATTCTAAACCAAAA
CAGAGTGGATTGGGCTGCAGGCTCTATGGGGTTCGTTATGCCAAAGTGTCTACATGTGCCACCAACATAAAACAAAACCAAGCCTTGGCT
CGTTCTCTTCTCTCTTCAATCTCTGGAAAAATAAGTACATATAGTTGATAACCCCTCTTAGCTTACAGGAAGCTTTTTGTATTAATTGCC
TTTGAGGTTATTTTCCGCCAGACCTCAACCTGGGTCAAAGTGGTACAGGAAGGCTTGCAGTATGATGGCAGGAGAATCAGCCTGGGGCCT
GGGGATGTAACCAAGCTGTACCCTTGAGACCTGGAACCAGAGCCACAGGCCCCTTTTGTGGGTTTCTCTGTGCTCTGAATGGGAGCCAGA
ATTCACTAGGAGGTCATCAACCGATGGTCCTCACAAGCCTCTTCTGAAGATGGAAGGCCTTTTGCCCGTTGAGGTAGAGGGGAAGGAAAT
CTCCTCTTTTGTACCCAATACTTATGTTGTATTGTTGGTGCGAAAGTAAAAACACTACCTCTTTTGAGACTTTGCCCAGGGTCCTGTGCC
TGGATGGGGGTGCAGGCAGCCTTGACCACGGCTGTTCCCCTCACCCAAAAGAATTATCATCCCAACAGCCAAGACCCAACAGGTGCTGAA
CTGTGCATCAACCAGGAAGAGTTCTATCCCCAAGCTGGCCACTATCACATATGCTTACTCTTGCTTAAAATTAATAAATCATGTTTTGAT
GAGAAAAAACTATTCTATTTCACTAGCTTAGTTGTCTCTTTTTCCAAATCTTCTCTGGAAGTAGGTTGGCTATTACCCTGTTGGGAAACA
GGGAAATGGCCTGATGCCCCTATTTCTGACCAGCTGTCAGGGAAGGAAGATGCAAGATGTGCAGAAGACACAAGGTAACGTCTACTTATC
CCCGTGCTTCGAAACCGTGTGTTTCCCTTTGCAGAACTGGTTAGCCTCAAGCATACCCATCCAATCAGCTTAAATTGTTCAGCAGTTGAC
CTCTGTGCTTCTTCCTTTGGGGGTGTTTAATCTTTGGTAACAGTTGTGCAGTGGTAGCCTTATTTCGGGGGGCAGTCCCTACTTTCTGTC
ACTTATCGAGGCCTTTGCCAAAGAAAAGTGGAAGCCGTTTCCTTGACATAGCCTTATATGACCTGATGTCATTAGGAGAAGAGTTAAAAG
ACAGTATCCCCTCTCTCCTGCTTGTGTGCCAAGTTCAGTGTTCCCTTTGCATTTTTTTGGGGTGGGTTGGCTATATTACAGAATTCCACC
AAAAGTGCTAAGTGTCCCCTCCTGCAGAAGTATCGTTTGTATTCACAGTAGGCTACGTGTGGATGTTTCAGCCATCTGCTCTGCTCCCTG
GGTCCCCGGGTCACCACCATACTGAGAAATATAGGACTCTGCCAAAGAGACGTGGAGGCCACGTCGGCTTGTCATGGTGTCCTGGAAGAC
TCTCCAGCAGCCAGAAGAACCTTCTGTGCTGTTTTCACTAGAGAAGATTTGAGTTGCAGCCTCTTGGAAAGAACATGACGGCACGGAACG
GGAGGAGGGGGCTCTTGTATCAGGGCCCGTTGTCACATCCGCTCTCAGCTTGTTGAAAACTCATAATCTCAGAATGCATTTCACACGGAG
AGATGTCTGGAAGTCCAATTCTCATCCCATTGGCTTTTTCCGTGGTTGCTGTTTTGTGGGCCGCTTTGCACAGGAGTGAAGCCAACACCC
CTAGATTGTGCCTTCACCCTTGCTGTGAAAAATTCAAAGCCCTGAAATAAGAGGAGGGAATCGCAGACATGCCCTGATTAGTTTTCCTGC
TTATTTCTTCATACAGGCATCTTCTGTTCCGTTGTATTGTGTTAGGTTTCAGAGGCGGGGAGCTTCCTCCTGCAGCAGATGAACAGGCAT
AGTTCTTAAAATACAGGAAAGTAACAAGTGAGGTTTCCAGGTAGAGTAGGTGAATGAAGTTTGCCGTCATGCTCTGTATTTCATATCAGA
TTTCTTTATCTTTTCATATCGCATGTCATTGGATGTGACATTTTGATGAAAATACTGAAACTACAAAAGCATAACTTCGCAACAAGAATG
AGATAGACAATTGAATGTGGGACATTTTTCTGGCATGTCTTGCTGCTGAGAATCGGACTTCCAGTCAAAACCCTGTTAGTGACACCCACC
TCCTCCAGTTATGCAAATTGATGCTTAGCTTGGCAAGCTTTCAAGGAGGTTTGCTTGGAACAGGAAAGGAATTAACAACCCTTTGAGGGT
GTCATTTTTACCTTGTAATACACTGTGGAAAATTCTGGAAGACGGTCCTTGCCTGAAAAGGTGCAACTTAGCATTAGGTTGTTATCAGAA
ACCTTGTCAAGTCTGATGGGAAATGAATAGATGCTGCTTTATTTCCTTGATAACTTCTTTGGAAGTCTGAAATAAATCCTGCCTTCAGTA
ACTGAAACCATTTATTAAAAATAGCAAGAAACAAGATGGGGACCAATTCTATTTTTATTCTTGGGAATTTGAAAGAGCCACAAGTGATTG
GTGTCCGATCTCCCAGCATATACTGTACACTATTTTGTATTTCTCCTGAACCAAAACCAAGTACTTAGCACTCAAGAAACAGATGCCCTG
TGTGTGACCGAGGGGAGTGTTTTTCCACAACAGGTTCCACTTCTGAACACTTGGAAGGACCTTGCCTGATTCATGGTGAAACACAGAGGT
TTTGGTTGGAGATAAATTTGGGGTCAGTTACTGTTCAAAATTGTGAAAGTAGTTCCCAGGAAGACAGCATTAGTGACTCCGCAGTGCTTT
GGGTAATAGATTTTGAAAAGCAATTGTGAGTTGGGGATTCCATCATTTCATTTAAGAGGTGAAGAGGGATTTAATTATTTAATACGCCGG
GTGCAAACTTGTTAAATTCCTCTTTCCCTGTCCCTGCTTGGTGGAGCTGCCACGTGTGGTTCAGTTCTAAGTTCTGGACTAGTGCCACTC
GATATCATTGGGAATAAATCGTTGTTCAACAGTCTGTTCCACAAACAACAGTAATTGAATTTCACAGACTTTATCCTGATTAGTGGAAAT
CAAATAATGGAGTGGAATCCCCATGTGTTTTCTCTTGCACAAACTTATTAGACTTGATTAGAAAACTGTTTGGAGGAAAAACTTGCCAGT
AAGTTTTTTGGTTGTTGTTTTGTTTTTTTTGAAAAACGACGCAACACCATAAAGTGTAAAATTAGGGGTTCTGGCCAAGAGAGGTACTAG
ATTTTTTTAATGCCGAGAAAAGTCCATGCCACAGAAGTTATTGTGTATGTCTCTAGGGAGCTTTAAGAATTTCACGTTTGAACTTTACAG
CTGTTTACCAATTAAATGGCAAGCTGGAAAAATACATTTTGAGAGGGGTAGAAAGAATAAGAATATAATTAAAAGTATGCTAACAAAATA
AGCAGTACATATTTTTTTAGAAAATGCAGTTTAGGCCAGGCACGGTAGCTCGTGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGT
GGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGGACAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCAACGATG
GTGATGCCTGTCTGTAATCCCAGCTACTCTGGAGGCTGAGGCAGGAGAATCGCTTGAACCGGGGAGGCAGAGGTTGTAGTGAGCCAAGAT
TGCGCCACTGCACTCCAGCCTGGGCAACAGAGCAAGACTCCGTCTCAAAAAAGGAAAGAAAATGCAGTTTCATTCCAGCCATCCTTAGAT
TTCTTTTCCCCTTAAAGTGGCTGAATCCATTGGAGATGTGATTTATTTTGCAGATCCACCAATTCCAAACTTCAGGAATATTCAAGCGGG
AGTCATGTGTAAGTGACAGCTTTGACAAAGAGAGACTGTGGCTGGGTGGCCCGGGTGTTGCCCACGCGGAGCAAGGATTGGTTCATTCAA
CGGATGGAGAGTACAGGATGGCTGGGACCTGGGAAGTTCCAGAATCTGAAAAGAGGGCAGGGCAAGAAGGAGCCAGAAGAGAGGTCCCAC
CCCTCAGTTGGCAGTGGGGCACGGAGGTCCGCATCAGCCAAGAACGTCCCCAGGATGCCGTGGGCACCTCATTTCACCCCACGTTTTTGG
CACAGTCTACTTTTTAGGTATTTTGTAAAGGAACTTCTCAGGATTGATTATTTGCCAGAGGAACAATTAGGCCAAGAGAAACTTGCTTGA
CAGCCATGTGTAAAACACGTCTGTCCTAATCAAACTAGAGATGCCTCAAGGCCCACGCAGGACACAGGCAGGTTCAAGGTCATGCACCTG
GAAATTTGTAGGGGAGGGTCAAGCAACTGAGGCCAAAGGGGGCCGGTAAAGTGGCTTCTGGGGTCTGAGCATCTGGAAGGCTCCTGGCAG
CAGTTACCTGACAGTGTCGTTGAGGGGCACGGCAGCTGGGCCCTCACCGTTTCCGCCAGCTCTGCTGAGCCAGCCCAGCCCATGCATTCC
GAACATCCGACAGCTTCTTTCTCCAGAATGTCTTCTGTCAGAGACTTCCAGGAAAGGAGCTCCCTCCTGTCTCACTGCTGTCAGCGTGGG
AGCCCTGCTCCCCAGGCTCCACGTCCCCGGAAGGTCCATCTTGTCCTGGAGCACACCCAGCCCCATTCAGGGTCAGTGCAGGAGGGAACA
GGGAATCTGCATTTCAGTAAGCTCCCCAGGTGAGGCTGCAGAGCAGAAACCACGGCTTTCAGACGTGAGCAGGCTCCCTGGGCTCTTGGT
GTCACCCTGTTAGCCACATCTGCGGAATGTGGAAGGCAGAACATAGCCACGCTGCTTAGTGCTGCCAGCGAACCTCAGGTTGCATCAGTG
GCTGGAATCTATCACAGCTGTTGGGGATACGTAACTCCCAGCAATAAATCCAGTATTTTCTTCCCTGCCCTGAGCTTCCTCTGGGTTTCT
TATCAGCAGCTATTACACACAGATGTCCAGTGCTTCTAAACTAAATTGTACTGTGTAACTTTTACATCACACTTGTGTGCTTAAAAAGCA
CACCGTGGGTAGTGACTGGGCCAAGAGACATCACAAAGCTTCCTGATAAATTTGAATCCAGCCACGGCAAGAGCGACGTGCGGGTACCTG
GTCCCTGATGCTTGGGTGCCCCGTTGAGCCTCGGGTACTTCTTGGACACTATTGTGAGAGCAGCCATCCTGGTGTCTCTGCCAGCATCTT
GGGGAACGCTGTGATGGTAAAATATCTGTCTCTCCTCTGGGAATCAGGGCAGCCCTGAGAAGTGAGCAGTTCCCTTTACAGATGGATAAT
TGTTTGTGTAAGACCAACCAGATAAAGTCCAAACTGTGTAGAACACACGTGTGCCTCACACATAGCCATCTGAGTAAAATATTTTTTCCA
ATGTAGATTTATAATTAGAAATGACAGATTTATAATATAGACTTCAGTAAGTTGGGCACAGCTGTCACTTTCGTGGTATCAATAAAAGGC
TAGAAACCTTGGGTGTCCTTGGCAACCTAGCCTTTGACATTGATGTTTTTCCATAGGATTTTCTTCATTTGGGTTGGAATAAAAATGCAT
TTTTATTCACAAGGCACAGACAGATAAGAATATCATAAGCAGGGAAGTGTCTCCAAAGGTCAGGACATATGTTTTTCTGTTGAGTGCTAT
ATGTGGAGGTCATTGCAAGTTCCCTGATATGAGTATGGTTTCGCTTGCTACATTGTGCCTATTAAAGTAAAATTTTACACAAGCCTCGCA
TTTCTAAGATTAGTGTTCCTGAATGAAATGTTAAGAAAACATTAAAAGATTATCTCTTTTTAAGATGGAGGAAAAAAAGTGAACAAAGCT
AATTAATCTATCATGAAAATTGCACAAAATAACATTTCTTAACAAATTTAATACAATTTTGTGTTCTTTGTTGCTAGTGGTATAAAACGA
GATTTTTTTCCCTCATTTTTCTCATTGTAGATGTCATCTCTCACATTTATATCAGTGAGGTTTGAAATTCTGTGTAGCAGTTACTCAGCA
CATATGAGAGGGCAGCGAATGAATGAGATTTGTCATGTGCTAATAAAAGCTGAATTTTTGTAATCTAAAATGATGTATTTTCTACTATTG
CTGTTAATTTGCATTGTTAAAAATTCTTAAAGTTTAATATGTTATGTTCAGTCATTGAAAGCGACCACTCATTTTTTTCTTAAAGTTGAT
GCCTTTTCTGCTGTGCTAGAGTCAGTATTTTGCTTCTGGCAGGAGAGCTGCAAACTGTGTATCCTCAAACAGATGCAAAAAGTAGTGCTT
TGCAAAACGTTTGTTTTCTGTTTATCTCAGATTAACATCCTTTAATACAAGTTTCTTAAGTGTAACTTGTATTTCTGAAAATGCTTAAAA
TTATTTTATATTTCCCTTTGGGAATTTTTCTCTATTTCCAGCACGCTGATTTGATTTAAAAATGTAATAAGACCAAGAGTTGGAGTAAAG
GGATATTCATTCCATGTTAAAAGTGGCTTCATAGCTACTGACAAATGTCTGAACTATTGTCGTGCCCTTCAAAACTGGAGTTTTCTAAAA

>351_351_18_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000398449_BACE2_chr21_42598193_ENST00000347667_length(amino acids)=772AA_BP=408
MACLMAAFSVGTAMNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSLPRRAAVNIEFRDLSYSVPEGP
WWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPHLTVQEAMMV
SAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKGLAQGGRSII
CTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDSDHKRDLGGD
AEVNPFLWHRPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSLQILVDTGSSNFAVAGTPHSYIDTYFDTERSSTYRSKGFDVT
VKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNVFSMQMCGAG
LPVAGSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFDAVVEAVARA
SLLYIQPMMGAGLNYECYRFGISPSTNALVIGATVMEGFYVIFDRAQKRVGFAASPCAEIAGAAVSEISGPFSTEDVASNCVPAQSLSEP

--------------------------------------------------------------
>351_351_19_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000398457_BACE2_chr21_42598193_ENST00000328735_length(transcript)=3539nt_BP=1490nt
AGACACTGAATCATCATTTGTAGTTTGGGGGGCTTTACATGCCTGCAGTGGTGAAAACTGAAATTTTGTCCCACTTAAGGGAGTTTCTTC
TTCCCTTTATTAATTGCAAAATAAATATATGTCACTTCAGAGGGCAGCAGCTGGACTACCTATGTTTGTGGCGCTACACCAACCTGAACT
TCGCTTCCTGAGACCTAAGATTCAGCCCCGTGCTCAGCAGACATCAGGGATCACCGACTCTGTGCCAGGAGCTGTTCTTGATGCTGGGAA
CGCAGGGGTGGACAAAACAGAGAAAGCCCTGCCCTCAGAATGCCAGCAGTTACTCTGCAGAGATGACGGAGCCCAAGTCGGTGTGTGTCT
CGGTGGATGAGGTGGTGTCCAGCAACATGGAGGCCACTGAGACGGACCTGCTGAATGGACATCTGAAAAAAGTAGATAATAACCTCACGG
AAGCCCAGCGCTTCTCCTCCTTGCCTCGGAGGGCAGCTGTGAACATTGAATTCAGGGACCTTTCCTATTCGGTTCCTGAAGGACCCTGGT
GGAGGAAGAAAGGATACAAGACCCTCCTGAAAGGAATTTCCGGGAAGTTCAATAGTGGTGAGTTGGTGGCCATTATGGGTCCTTCCGGGG
CCGGGAAGTCCACGCTGATGAACATCCTGGCTGGATACAGGGAGACGGGCATGAAGGGGGCCGTCCTCATCAACGGCCTGCCCCGGGACC
TGCGCTGCTTCCGGAAGGTGTCCTGCTACATCATGCAGGATGACATGCTGCTGCCGCATCTCACTGTGCAGGAGGCCATGATGGTGTCGG
CACATCTGAAGCTTCAGGAGAAGGATGAAGGCAGAAGGGAAATGGTCAAGGAGATACTGACAGCGCTGGGCTTGCTGTCTTGCGCCAACA
CGCGGACCGGGAGCCTGTCAGGTGGTCAGCGCAAGCGCCTGGCCATCGCGCTGGAGCTGGTGAACAACCCTCCAGTCATGTTCTTCGATG
AGCCCACCAGCGGCCTGGACAGCGCCTCCTGCTTCCAGGTGGTCTCGCTGATGAAAGGGCTCGCTCAAGGGGGTCGCTCCATCATTTGCA
CCATCCACCAGCCCAGCGCCAAACTCTTCGAGCTGTTCGACCAGCTTTACGTCCTGAGTCAAGGACAATGTGTGTACCGGGGAAAAGTCT
GCAATCTTGTGCCATATTTGAGGGATTTGGGTCTGAACTGCCCAACCTACCACAACCCAGCAGATTTTGTCATGGAGGTTGCATCCGGCG
AGTACGGTGATCAGAACAGTCGGCTGGTGAGAGCGGTTCGGGAGGGCATGTGTGACTCAGACCACAAGAGAGACCTCGGGGGTGATGCCG
AGGTGAACCCTTTTCTTTGGCACCGGCCCTCTGAAGAGGACTCCTCGTCCATGGAAGGCTGCCACAGCTTCTCTGCCAGCTGCCTCACGC
AGTTCTGCATCCTCTTCAAGAGGACCTTCCTCAGCATCATGAGGGACTCGCTACAGATTCTCGTTGACACTGGAAGCAGTAACTTTGCCG
TGGCAGGAACCCCGCACTCCTACATAGACACGTACTTTGACACAGAGAGGTCTAGCACATACCGCTCCAAGGGCTTTGACGTCACAGTGA
AGTACACACAAGGAAGCTGGACGGGCTTCGTTGGGGAAGACCTCGTCACCATCCCCAAAGGCTTCAATACTTCTTTTCTTGTCAACATTG
CCACTATTTTTGAATCAGAGAATTTCTTTTTGCCTGGGATTAAATGGAATGGAATACTTGGCCTAGCTTATGCCACACTTGCCAAGCCAT
CAAGTTCTCTGGAGACCTTCTTCGACTCCCTGGTGACACAAGCAAACATCCCCAACGTTTTCTCCATGCAGATGTGTGGAGCCGGCTTGC
CCGTTGCTGGATCTGGGACCAACGGAGGTAGTCTTGTCTTGGGTGGAATTGAACCAAGTTTGTATAAAGGAGACATCTGGTATACCCCTA
TTAAGGAAGAGTGGTACTACCAGATAGAAATTCTGAAATTGGAAATTGGAGGCCAAAGCCTTAATCTGGACTGCAGAGAGTATAACGCAG
ACAAGGCCATCGTGGACAGTGGCACCACGCTGCTGCGCCTGCCCCAGAAGGTGTTTGATGCGGTGGTGGAAGCTGTGGCCCGCGCATCTC
TGATTCCAGAATTCTCTGATGGTTTCTGGACTGGGTCCCAGCTGGCGTGCTGGACGAATTCGGAAACACCTTGGTCTTACTTCCCTAAAA
TCTCCATCTACCTGAGAGACGAGAACTCCAGCAGGTCATTCCGTATCACAATCCTGCCTCAGAAATTGCAGGTGCTGCAGTGTCTGAAAT
TTCCGGGCCTTTCTCAACAGAGGATGTAGCCAGCAACTGTGTCCCCGCTCAGTCTTTGAGCGAGCCCATTTTGTGGATTGTGTCCTATGC
GCTCATGAGCGTCTGTGGAGCCATCCTCCTTGTCTTAATCGTCCTGCTGCTGCTGCCGTTCCGGTGTCAGCGTCGCCCCCGTGACCCTGA
GGTCGTCAATGATGAGTCCTCTCTGGTCAGACATCGCTGGAAATGAATAGCCAGGCCTGACCTCAAGCAACCATGAACTCAGCTATTAAG
AAAATCACATTTCCAGGGCAGCAGCCGGGATCGATGGTGGCGCTTTCTCCTGTGCCCACCCGTCTTCAATCTCTGTTCTGCTCCCAGATG
CCTTCTAGATTCACTGTCTTTTGATTCTTGATTTTCAAGCTTTCAAATCCTCCCTACTTCCAAGAAAAATAATTAAAAAAAAAACTTCAT
TCTAAACCAAAACAGAGTGGATTGGGCTGCAGGCTCTATGGGGTTCGTTATGCCAAAGTGTCTACATGTGCCACCAACATAAAACAAAAC
CAAGCCTTGGCTCGTTCTCTTCTCTCTTCAATCTCTGGAAAAATAAGTACATATAGTTGATAACCCCTCTTAGCTTACAGGAAGCTTTTT
GTATTAATTGCCTTTGAGGTTATTTTCCGCCAGACCTCAACCTGGGTCAAAGTGGTACAGGAAGGCTTGCAGTATGATGGCAGGAGAATC
AGCCTGGGGCCTGGGGATGTAACCAAGCTGTACCCTTGAGACCTGGAACCAGAGCCACAGGCCCCTTTTGTGGGTTTCTCTGTGCTCTGA
ATGGGAGCCAGAATTCACTAGGAGGTCATCAACCGATGGTCCTCACAAGCCTCTTCTGAAGATGGAAGGCCTTTTGCCCGTTGAGGTAGA
GGGGAAGGAAATCTCCTCTTTTGTACCCAATACTTATGTTGTATTGTTGGTGCGAAAGTAAAAACACTACCTCTTTTGAGACTTTGCCCA
GGGTCCTGTGCCTGGATGGGGGTGCAGGCAGCCTTGACCACGGCTGTTCCCCTCACCCAAAAGAATTATCATCCCAACAGCCAAGACCCA
ACAGGTGCTGAACTGTGCATCAACCAGGAAGAGTTCTATCCCCAAGCTGGCCACTATCACATATGCTTACTCTTGCTTAAAATTAATAAA

>351_351_19_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000398457_BACE2_chr21_42598193_ENST00000328735_length(amino acids)=709AA_BP=417
MCQELFLMLGTQGWTKQRKPCPQNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSLPRRAAVNIEFRD
LSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPH
LTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKG
LAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDS
DHKRDLGGDAEVNPFLWHRPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSLQILVDTGSSNFAVAGTPHSYIDTYFDTERSST
YRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNV
FSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFD

--------------------------------------------------------------
>351_351_20_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000398457_BACE2_chr21_42598193_ENST00000330333_length(transcript)=3708nt_BP=1490nt
AGACACTGAATCATCATTTGTAGTTTGGGGGGCTTTACATGCCTGCAGTGGTGAAAACTGAAATTTTGTCCCACTTAAGGGAGTTTCTTC
TTCCCTTTATTAATTGCAAAATAAATATATGTCACTTCAGAGGGCAGCAGCTGGACTACCTATGTTTGTGGCGCTACACCAACCTGAACT
TCGCTTCCTGAGACCTAAGATTCAGCCCCGTGCTCAGCAGACATCAGGGATCACCGACTCTGTGCCAGGAGCTGTTCTTGATGCTGGGAA
CGCAGGGGTGGACAAAACAGAGAAAGCCCTGCCCTCAGAATGCCAGCAGTTACTCTGCAGAGATGACGGAGCCCAAGTCGGTGTGTGTCT
CGGTGGATGAGGTGGTGTCCAGCAACATGGAGGCCACTGAGACGGACCTGCTGAATGGACATCTGAAAAAAGTAGATAATAACCTCACGG
AAGCCCAGCGCTTCTCCTCCTTGCCTCGGAGGGCAGCTGTGAACATTGAATTCAGGGACCTTTCCTATTCGGTTCCTGAAGGACCCTGGT
GGAGGAAGAAAGGATACAAGACCCTCCTGAAAGGAATTTCCGGGAAGTTCAATAGTGGTGAGTTGGTGGCCATTATGGGTCCTTCCGGGG
CCGGGAAGTCCACGCTGATGAACATCCTGGCTGGATACAGGGAGACGGGCATGAAGGGGGCCGTCCTCATCAACGGCCTGCCCCGGGACC
TGCGCTGCTTCCGGAAGGTGTCCTGCTACATCATGCAGGATGACATGCTGCTGCCGCATCTCACTGTGCAGGAGGCCATGATGGTGTCGG
CACATCTGAAGCTTCAGGAGAAGGATGAAGGCAGAAGGGAAATGGTCAAGGAGATACTGACAGCGCTGGGCTTGCTGTCTTGCGCCAACA
CGCGGACCGGGAGCCTGTCAGGTGGTCAGCGCAAGCGCCTGGCCATCGCGCTGGAGCTGGTGAACAACCCTCCAGTCATGTTCTTCGATG
AGCCCACCAGCGGCCTGGACAGCGCCTCCTGCTTCCAGGTGGTCTCGCTGATGAAAGGGCTCGCTCAAGGGGGTCGCTCCATCATTTGCA
CCATCCACCAGCCCAGCGCCAAACTCTTCGAGCTGTTCGACCAGCTTTACGTCCTGAGTCAAGGACAATGTGTGTACCGGGGAAAAGTCT
GCAATCTTGTGCCATATTTGAGGGATTTGGGTCTGAACTGCCCAACCTACCACAACCCAGCAGATTTTGTCATGGAGGTTGCATCCGGCG
AGTACGGTGATCAGAACAGTCGGCTGGTGAGAGCGGTTCGGGAGGGCATGTGTGACTCAGACCACAAGAGAGACCTCGGGGGTGATGCCG
AGGTGAACCCTTTTCTTTGGCACCGGCCCTCTGAAGAGGACTCCTCGTCCATGGAAGGCTGCCACAGCTTCTCTGCCAGCTGCCTCACGC
AGTTCTGCATCCTCTTCAAGAGGACCTTCCTCAGCATCATGAGGGACTCGCTACAGATTCTCGTTGACACTGGAAGCAGTAACTTTGCCG
TGGCAGGAACCCCGCACTCCTACATAGACACGTACTTTGACACAGAGAGGTCTAGCACATACCGCTCCAAGGGCTTTGACGTCACAGTGA
AGTACACACAAGGAAGCTGGACGGGCTTCGTTGGGGAAGACCTCGTCACCATCCCCAAAGGCTTCAATACTTCTTTTCTTGTCAACATTG
CCACTATTTTTGAATCAGAGAATTTCTTTTTGCCTGGGATTAAATGGAATGGAATACTTGGCCTAGCTTATGCCACACTTGCCAAGCCAT
CAAGTTCTCTGGAGACCTTCTTCGACTCCCTGGTGACACAAGCAAACATCCCCAACGTTTTCTCCATGCAGATGTGTGGAGCCGGCTTGC
CCGTTGCTGGATCTGGGACCAACGGAGGTAGTCTTGTCTTGGGTGGAATTGAACCAAGTTTGTATAAAGGAGACATCTGGTATACCCCTA
TTAAGGAAGAGTGGTACTACCAGATAGAAATTCTGAAATTGGAAATTGGAGGCCAAAGCCTTAATCTGGACTGCAGAGAGTATAACGCAG
ACAAGGCCATCGTGGACAGTGGCACCACGCTGCTGCGCCTGCCCCAGAAGGTGTTTGATGCGGTGGTGGAAGCTGTGGCCCGCGCATCTC
TGATTCCAGAATTCTCTGATGGTTTCTGGACTGGGTCCCAGCTGGCGTGCTGGACGAATTCGGAAACACCTTGGTCTTACTTCCCTAAAA
TCTCCATCTACCTGAGAGACGAGAACTCCAGCAGGTCATTCCGTATCACAATCCTGCCTCAGCTTTACATTCAGCCCATGATGGGGGCCG
GCCTGAATTATGAATGTTACCGATTCGGCATTTCCCCATCCACAAATGCGCTGGTGATCGGTGCCACGGTGATGGAGGGCTTCTACGTCA
TCTTCGACAGAGCCCAGAAGAGGGTGGGCTTCGCAGCGAGCCCCTGTGCAGAAATTGCAGGTGCTGCAGTGTCTGAAATTTCCGGGCCTT
TCTCAACAGAGGATGTAGCCAGCAACTGTGTCCCCGCTCAGTCTTTGAGCGAGCCCATTTTGTGGATTGTGTCCTATGCGCTCATGAGCG
TCTGTGGAGCCATCCTCCTTGTCTTAATCGTCCTGCTGCTGCTGCCGTTCCGGTGTCAGCGTCGCCCCCGTGACCCTGAGGTCGTCAATG
ATGAGTCCTCTCTGGTCAGACATCGCTGGAAATGAATAGCCAGGCCTGACCTCAAGCAACCATGAACTCAGCTATTAAGAAAATCACATT
TCCAGGGCAGCAGCCGGGATCGATGGTGGCGCTTTCTCCTGTGCCCACCCGTCTTCAATCTCTGTTCTGCTCCCAGATGCCTTCTAGATT
CACTGTCTTTTGATTCTTGATTTTCAAGCTTTCAAATCCTCCCTACTTCCAAGAAAAATAATTAAAAAAAAAACTTCATTCTAAACCAAA
ACAGAGTGGATTGGGCTGCAGGCTCTATGGGGTTCGTTATGCCAAAGTGTCTACATGTGCCACCAACATAAAACAAAACCAAGCCTTGGC
TCGTTCTCTTCTCTCTTCAATCTCTGGAAAAATAAGTACATATAGTTGATAACCCCTCTTAGCTTACAGGAAGCTTTTTGTATTAATTGC
CTTTGAGGTTATTTTCCGCCAGACCTCAACCTGGGTCAAAGTGGTACAGGAAGGCTTGCAGTATGATGGCAGGAGAATCAGCCTGGGGCC
TGGGGATGTAACCAAGCTGTACCCTTGAGACCTGGAACCAGAGCCACAGGCCCCTTTTGTGGGTTTCTCTGTGCTCTGAATGGGAGCCAG
AATTCACTAGGAGGTCATCAACCGATGGTCCTCACAAGCCTCTTCTGAAGATGGAAGGCCTTTTGCCCGTTGAGGTAGAGGGGAAGGAAA
TCTCCTCTTTTGTACCCAATACTTATGTTGTATTGTTGGTGCGAAAGTAAAAACACTACCTCTTTTGAGACTTTGCCCAGGGTCCTGTGC
CTGGATGGGGGTGCAGGCAGCCTTGACCACGGCTGTTCCCCTCACCCAAAAGAATTATCATCCCAACAGCCAAGACCCAACAGGTGCTGA
ACTGTGCATCAACCAGGAAGAGTTCTATCCCCAAGCTGGCCACTATCACATATGCTTACTCTTGCTTAAAATTAATAAATCATGTTTTGA

>351_351_20_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000398457_BACE2_chr21_42598193_ENST00000330333_length(amino acids)=831AA_BP=417
MCQELFLMLGTQGWTKQRKPCPQNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSLPRRAAVNIEFRD
LSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPH
LTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKG
LAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDS
DHKRDLGGDAEVNPFLWHRPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSLQILVDTGSSNFAVAGTPHSYIDTYFDTERSST
YRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNV
FSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFD
AVVEAVARASLIPEFSDGFWTGSQLACWTNSETPWSYFPKISIYLRDENSSRSFRITILPQLYIQPMMGAGLNYECYRFGISPSTNALVI
GATVMEGFYVIFDRAQKRVGFAASPCAEIAGAAVSEISGPFSTEDVASNCVPAQSLSEPILWIVSYALMSVCGAILLVLIVLLLLPFRCQ

--------------------------------------------------------------
>351_351_21_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000398457_BACE2_chr21_42598193_ENST00000347667_length(transcript)=9479nt_BP=1490nt
AGACACTGAATCATCATTTGTAGTTTGGGGGGCTTTACATGCCTGCAGTGGTGAAAACTGAAATTTTGTCCCACTTAAGGGAGTTTCTTC
TTCCCTTTATTAATTGCAAAATAAATATATGTCACTTCAGAGGGCAGCAGCTGGACTACCTATGTTTGTGGCGCTACACCAACCTGAACT
TCGCTTCCTGAGACCTAAGATTCAGCCCCGTGCTCAGCAGACATCAGGGATCACCGACTCTGTGCCAGGAGCTGTTCTTGATGCTGGGAA
CGCAGGGGTGGACAAAACAGAGAAAGCCCTGCCCTCAGAATGCCAGCAGTTACTCTGCAGAGATGACGGAGCCCAAGTCGGTGTGTGTCT
CGGTGGATGAGGTGGTGTCCAGCAACATGGAGGCCACTGAGACGGACCTGCTGAATGGACATCTGAAAAAAGTAGATAATAACCTCACGG
AAGCCCAGCGCTTCTCCTCCTTGCCTCGGAGGGCAGCTGTGAACATTGAATTCAGGGACCTTTCCTATTCGGTTCCTGAAGGACCCTGGT
GGAGGAAGAAAGGATACAAGACCCTCCTGAAAGGAATTTCCGGGAAGTTCAATAGTGGTGAGTTGGTGGCCATTATGGGTCCTTCCGGGG
CCGGGAAGTCCACGCTGATGAACATCCTGGCTGGATACAGGGAGACGGGCATGAAGGGGGCCGTCCTCATCAACGGCCTGCCCCGGGACC
TGCGCTGCTTCCGGAAGGTGTCCTGCTACATCATGCAGGATGACATGCTGCTGCCGCATCTCACTGTGCAGGAGGCCATGATGGTGTCGG
CACATCTGAAGCTTCAGGAGAAGGATGAAGGCAGAAGGGAAATGGTCAAGGAGATACTGACAGCGCTGGGCTTGCTGTCTTGCGCCAACA
CGCGGACCGGGAGCCTGTCAGGTGGTCAGCGCAAGCGCCTGGCCATCGCGCTGGAGCTGGTGAACAACCCTCCAGTCATGTTCTTCGATG
AGCCCACCAGCGGCCTGGACAGCGCCTCCTGCTTCCAGGTGGTCTCGCTGATGAAAGGGCTCGCTCAAGGGGGTCGCTCCATCATTTGCA
CCATCCACCAGCCCAGCGCCAAACTCTTCGAGCTGTTCGACCAGCTTTACGTCCTGAGTCAAGGACAATGTGTGTACCGGGGAAAAGTCT
GCAATCTTGTGCCATATTTGAGGGATTTGGGTCTGAACTGCCCAACCTACCACAACCCAGCAGATTTTGTCATGGAGGTTGCATCCGGCG
AGTACGGTGATCAGAACAGTCGGCTGGTGAGAGCGGTTCGGGAGGGCATGTGTGACTCAGACCACAAGAGAGACCTCGGGGGTGATGCCG
AGGTGAACCCTTTTCTTTGGCACCGGCCCTCTGAAGAGGACTCCTCGTCCATGGAAGGCTGCCACAGCTTCTCTGCCAGCTGCCTCACGC
AGTTCTGCATCCTCTTCAAGAGGACCTTCCTCAGCATCATGAGGGACTCGCTACAGATTCTCGTTGACACTGGAAGCAGTAACTTTGCCG
TGGCAGGAACCCCGCACTCCTACATAGACACGTACTTTGACACAGAGAGGTCTAGCACATACCGCTCCAAGGGCTTTGACGTCACAGTGA
AGTACACACAAGGAAGCTGGACGGGCTTCGTTGGGGAAGACCTCGTCACCATCCCCAAAGGCTTCAATACTTCTTTTCTTGTCAACATTG
CCACTATTTTTGAATCAGAGAATTTCTTTTTGCCTGGGATTAAATGGAATGGAATACTTGGCCTAGCTTATGCCACACTTGCCAAGCCAT
CAAGTTCTCTGGAGACCTTCTTCGACTCCCTGGTGACACAAGCAAACATCCCCAACGTTTTCTCCATGCAGATGTGTGGAGCCGGCTTGC
CCGTTGCTGGATCTGGGACCAACGGAGGTAGTCTTGTCTTGGGTGGAATTGAACCAAGTTTGTATAAAGGAGACATCTGGTATACCCCTA
TTAAGGAAGAGTGGTACTACCAGATAGAAATTCTGAAATTGGAAATTGGAGGCCAAAGCCTTAATCTGGACTGCAGAGAGTATAACGCAG
ACAAGGCCATCGTGGACAGTGGCACCACGCTGCTGCGCCTGCCCCAGAAGGTGTTTGATGCGGTGGTGGAAGCTGTGGCCCGCGCATCTC
TGCTTTACATTCAGCCCATGATGGGGGCCGGCCTGAATTATGAATGTTACCGATTCGGCATTTCCCCATCCACAAATGCGCTGGTGATCG
GTGCCACGGTGATGGAGGGCTTCTACGTCATCTTCGACAGAGCCCAGAAGAGGGTGGGCTTCGCAGCGAGCCCCTGTGCAGAAATTGCAG
GTGCTGCAGTGTCTGAAATTTCCGGGCCTTTCTCAACAGAGGATGTAGCCAGCAACTGTGTCCCCGCTCAGTCTTTGAGCGAGCCCATTT
TGTGGATTGTGTCCTATGCGCTCATGAGCGTCTGTGGAGCCATCCTCCTTGTCTTAATCGTCCTGCTGCTGCTGCCGTTCCGGTGTCAGC
GTCGCCCCCGTGACCCTGAGGTCGTCAATGATGAGTCCTCTCTGGTCAGACATCGCTGGAAATGAATAGCCAGGCCTGACCTCAAGCAAC
CATGAACTCAGCTATTAAGAAAATCACATTTCCAGGGCAGCAGCCGGGATCGATGGTGGCGCTTTCTCCTGTGCCCACCCGTCTTCAATC
TCTGTTCTGCTCCCAGATGCCTTCTAGATTCACTGTCTTTTGATTCTTGATTTTCAAGCTTTCAAATCCTCCCTACTTCCAAGAAAAATA
ATTAAAAAAAAAACTTCATTCTAAACCAAAACAGAGTGGATTGGGCTGCAGGCTCTATGGGGTTCGTTATGCCAAAGTGTCTACATGTGC
CACCAACATAAAACAAAACCAAGCCTTGGCTCGTTCTCTTCTCTCTTCAATCTCTGGAAAAATAAGTACATATAGTTGATAACCCCTCTT
AGCTTACAGGAAGCTTTTTGTATTAATTGCCTTTGAGGTTATTTTCCGCCAGACCTCAACCTGGGTCAAAGTGGTACAGGAAGGCTTGCA
GTATGATGGCAGGAGAATCAGCCTGGGGCCTGGGGATGTAACCAAGCTGTACCCTTGAGACCTGGAACCAGAGCCACAGGCCCCTTTTGT
GGGTTTCTCTGTGCTCTGAATGGGAGCCAGAATTCACTAGGAGGTCATCAACCGATGGTCCTCACAAGCCTCTTCTGAAGATGGAAGGCC
TTTTGCCCGTTGAGGTAGAGGGGAAGGAAATCTCCTCTTTTGTACCCAATACTTATGTTGTATTGTTGGTGCGAAAGTAAAAACACTACC
TCTTTTGAGACTTTGCCCAGGGTCCTGTGCCTGGATGGGGGTGCAGGCAGCCTTGACCACGGCTGTTCCCCTCACCCAAAAGAATTATCA
TCCCAACAGCCAAGACCCAACAGGTGCTGAACTGTGCATCAACCAGGAAGAGTTCTATCCCCAAGCTGGCCACTATCACATATGCTTACT
CTTGCTTAAAATTAATAAATCATGTTTTGATGAGAAAAAACTATTCTATTTCACTAGCTTAGTTGTCTCTTTTTCCAAATCTTCTCTGGA
AGTAGGTTGGCTATTACCCTGTTGGGAAACAGGGAAATGGCCTGATGCCCCTATTTCTGACCAGCTGTCAGGGAAGGAAGATGCAAGATG
TGCAGAAGACACAAGGTAACGTCTACTTATCCCCGTGCTTCGAAACCGTGTGTTTCCCTTTGCAGAACTGGTTAGCCTCAAGCATACCCA
TCCAATCAGCTTAAATTGTTCAGCAGTTGACCTCTGTGCTTCTTCCTTTGGGGGTGTTTAATCTTTGGTAACAGTTGTGCAGTGGTAGCC
TTATTTCGGGGGGCAGTCCCTACTTTCTGTCACTTATCGAGGCCTTTGCCAAAGAAAAGTGGAAGCCGTTTCCTTGACATAGCCTTATAT
GACCTGATGTCATTAGGAGAAGAGTTAAAAGACAGTATCCCCTCTCTCCTGCTTGTGTGCCAAGTTCAGTGTTCCCTTTGCATTTTTTTG
GGGTGGGTTGGCTATATTACAGAATTCCACCAAAAGTGCTAAGTGTCCCCTCCTGCAGAAGTATCGTTTGTATTCACAGTAGGCTACGTG
TGGATGTTTCAGCCATCTGCTCTGCTCCCTGGGTCCCCGGGTCACCACCATACTGAGAAATATAGGACTCTGCCAAAGAGACGTGGAGGC
CACGTCGGCTTGTCATGGTGTCCTGGAAGACTCTCCAGCAGCCAGAAGAACCTTCTGTGCTGTTTTCACTAGAGAAGATTTGAGTTGCAG
CCTCTTGGAAAGAACATGACGGCACGGAACGGGAGGAGGGGGCTCTTGTATCAGGGCCCGTTGTCACATCCGCTCTCAGCTTGTTGAAAA
CTCATAATCTCAGAATGCATTTCACACGGAGAGATGTCTGGAAGTCCAATTCTCATCCCATTGGCTTTTTCCGTGGTTGCTGTTTTGTGG
GCCGCTTTGCACAGGAGTGAAGCCAACACCCCTAGATTGTGCCTTCACCCTTGCTGTGAAAAATTCAAAGCCCTGAAATAAGAGGAGGGA
ATCGCAGACATGCCCTGATTAGTTTTCCTGCTTATTTCTTCATACAGGCATCTTCTGTTCCGTTGTATTGTGTTAGGTTTCAGAGGCGGG
GAGCTTCCTCCTGCAGCAGATGAACAGGCATAGTTCTTAAAATACAGGAAAGTAACAAGTGAGGTTTCCAGGTAGAGTAGGTGAATGAAG
TTTGCCGTCATGCTCTGTATTTCATATCAGATTTCTTTATCTTTTCATATCGCATGTCATTGGATGTGACATTTTGATGAAAATACTGAA
ACTACAAAAGCATAACTTCGCAACAAGAATGAGATAGACAATTGAATGTGGGACATTTTTCTGGCATGTCTTGCTGCTGAGAATCGGACT
TCCAGTCAAAACCCTGTTAGTGACACCCACCTCCTCCAGTTATGCAAATTGATGCTTAGCTTGGCAAGCTTTCAAGGAGGTTTGCTTGGA
ACAGGAAAGGAATTAACAACCCTTTGAGGGTGTCATTTTTACCTTGTAATACACTGTGGAAAATTCTGGAAGACGGTCCTTGCCTGAAAA
GGTGCAACTTAGCATTAGGTTGTTATCAGAAACCTTGTCAAGTCTGATGGGAAATGAATAGATGCTGCTTTATTTCCTTGATAACTTCTT
TGGAAGTCTGAAATAAATCCTGCCTTCAGTAACTGAAACCATTTATTAAAAATAGCAAGAAACAAGATGGGGACCAATTCTATTTTTATT
CTTGGGAATTTGAAAGAGCCACAAGTGATTGGTGTCCGATCTCCCAGCATATACTGTACACTATTTTGTATTTCTCCTGAACCAAAACCA
AGTACTTAGCACTCAAGAAACAGATGCCCTGTGTGTGACCGAGGGGAGTGTTTTTCCACAACAGGTTCCACTTCTGAACACTTGGAAGGA
CCTTGCCTGATTCATGGTGAAACACAGAGGTTTTGGTTGGAGATAAATTTGGGGTCAGTTACTGTTCAAAATTGTGAAAGTAGTTCCCAG
GAAGACAGCATTAGTGACTCCGCAGTGCTTTGGGTAATAGATTTTGAAAAGCAATTGTGAGTTGGGGATTCCATCATTTCATTTAAGAGG
TGAAGAGGGATTTAATTATTTAATACGCCGGGTGCAAACTTGTTAAATTCCTCTTTCCCTGTCCCTGCTTGGTGGAGCTGCCACGTGTGG
TTCAGTTCTAAGTTCTGGACTAGTGCCACTCGATATCATTGGGAATAAATCGTTGTTCAACAGTCTGTTCCACAAACAACAGTAATTGAA
TTTCACAGACTTTATCCTGATTAGTGGAAATCAAATAATGGAGTGGAATCCCCATGTGTTTTCTCTTGCACAAACTTATTAGACTTGATT
AGAAAACTGTTTGGAGGAAAAACTTGCCAGTAAGTTTTTTGGTTGTTGTTTTGTTTTTTTTGAAAAACGACGCAACACCATAAAGTGTAA
AATTAGGGGTTCTGGCCAAGAGAGGTACTAGATTTTTTTAATGCCGAGAAAAGTCCATGCCACAGAAGTTATTGTGTATGTCTCTAGGGA
GCTTTAAGAATTTCACGTTTGAACTTTACAGCTGTTTACCAATTAAATGGCAAGCTGGAAAAATACATTTTGAGAGGGGTAGAAAGAATA
AGAATATAATTAAAAGTATGCTAACAAAATAAGCAGTACATATTTTTTTAGAAAATGCAGTTTAGGCCAGGCACGGTAGCTCGTGCCTGT
AATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGGACAACATGGTGAAACCCCGTCTC
TACTAAAAATACAAAAAATTAGCCAACGATGGTGATGCCTGTCTGTAATCCCAGCTACTCTGGAGGCTGAGGCAGGAGAATCGCTTGAAC
CGGGGAGGCAGAGGTTGTAGTGAGCCAAGATTGCGCCACTGCACTCCAGCCTGGGCAACAGAGCAAGACTCCGTCTCAAAAAAGGAAAGA
AAATGCAGTTTCATTCCAGCCATCCTTAGATTTCTTTTCCCCTTAAAGTGGCTGAATCCATTGGAGATGTGATTTATTTTGCAGATCCAC
CAATTCCAAACTTCAGGAATATTCAAGCGGGAGTCATGTGTAAGTGACAGCTTTGACAAAGAGAGACTGTGGCTGGGTGGCCCGGGTGTT
GCCCACGCGGAGCAAGGATTGGTTCATTCAACGGATGGAGAGTACAGGATGGCTGGGACCTGGGAAGTTCCAGAATCTGAAAAGAGGGCA
GGGCAAGAAGGAGCCAGAAGAGAGGTCCCACCCCTCAGTTGGCAGTGGGGCACGGAGGTCCGCATCAGCCAAGAACGTCCCCAGGATGCC
GTGGGCACCTCATTTCACCCCACGTTTTTGGCACAGTCTACTTTTTAGGTATTTTGTAAAGGAACTTCTCAGGATTGATTATTTGCCAGA
GGAACAATTAGGCCAAGAGAAACTTGCTTGACAGCCATGTGTAAAACACGTCTGTCCTAATCAAACTAGAGATGCCTCAAGGCCCACGCA
GGACACAGGCAGGTTCAAGGTCATGCACCTGGAAATTTGTAGGGGAGGGTCAAGCAACTGAGGCCAAAGGGGGCCGGTAAAGTGGCTTCT
GGGGTCTGAGCATCTGGAAGGCTCCTGGCAGCAGTTACCTGACAGTGTCGTTGAGGGGCACGGCAGCTGGGCCCTCACCGTTTCCGCCAG
CTCTGCTGAGCCAGCCCAGCCCATGCATTCCGAACATCCGACAGCTTCTTTCTCCAGAATGTCTTCTGTCAGAGACTTCCAGGAAAGGAG
CTCCCTCCTGTCTCACTGCTGTCAGCGTGGGAGCCCTGCTCCCCAGGCTCCACGTCCCCGGAAGGTCCATCTTGTCCTGGAGCACACCCA
GCCCCATTCAGGGTCAGTGCAGGAGGGAACAGGGAATCTGCATTTCAGTAAGCTCCCCAGGTGAGGCTGCAGAGCAGAAACCACGGCTTT
CAGACGTGAGCAGGCTCCCTGGGCTCTTGGTGTCACCCTGTTAGCCACATCTGCGGAATGTGGAAGGCAGAACATAGCCACGCTGCTTAG
TGCTGCCAGCGAACCTCAGGTTGCATCAGTGGCTGGAATCTATCACAGCTGTTGGGGATACGTAACTCCCAGCAATAAATCCAGTATTTT
CTTCCCTGCCCTGAGCTTCCTCTGGGTTTCTTATCAGCAGCTATTACACACAGATGTCCAGTGCTTCTAAACTAAATTGTACTGTGTAAC
TTTTACATCACACTTGTGTGCTTAAAAAGCACACCGTGGGTAGTGACTGGGCCAAGAGACATCACAAAGCTTCCTGATAAATTTGAATCC
AGCCACGGCAAGAGCGACGTGCGGGTACCTGGTCCCTGATGCTTGGGTGCCCCGTTGAGCCTCGGGTACTTCTTGGACACTATTGTGAGA
GCAGCCATCCTGGTGTCTCTGCCAGCATCTTGGGGAACGCTGTGATGGTAAAATATCTGTCTCTCCTCTGGGAATCAGGGCAGCCCTGAG
AAGTGAGCAGTTCCCTTTACAGATGGATAATTGTTTGTGTAAGACCAACCAGATAAAGTCCAAACTGTGTAGAACACACGTGTGCCTCAC
ACATAGCCATCTGAGTAAAATATTTTTTCCAATGTAGATTTATAATTAGAAATGACAGATTTATAATATAGACTTCAGTAAGTTGGGCAC
AGCTGTCACTTTCGTGGTATCAATAAAAGGCTAGAAACCTTGGGTGTCCTTGGCAACCTAGCCTTTGACATTGATGTTTTTCCATAGGAT
TTTCTTCATTTGGGTTGGAATAAAAATGCATTTTTATTCACAAGGCACAGACAGATAAGAATATCATAAGCAGGGAAGTGTCTCCAAAGG
TCAGGACATATGTTTTTCTGTTGAGTGCTATATGTGGAGGTCATTGCAAGTTCCCTGATATGAGTATGGTTTCGCTTGCTACATTGTGCC
TATTAAAGTAAAATTTTACACAAGCCTCGCATTTCTAAGATTAGTGTTCCTGAATGAAATGTTAAGAAAACATTAAAAGATTATCTCTTT
TTAAGATGGAGGAAAAAAAGTGAACAAAGCTAATTAATCTATCATGAAAATTGCACAAAATAACATTTCTTAACAAATTTAATACAATTT
TGTGTTCTTTGTTGCTAGTGGTATAAAACGAGATTTTTTTCCCTCATTTTTCTCATTGTAGATGTCATCTCTCACATTTATATCAGTGAG
GTTTGAAATTCTGTGTAGCAGTTACTCAGCACATATGAGAGGGCAGCGAATGAATGAGATTTGTCATGTGCTAATAAAAGCTGAATTTTT
GTAATCTAAAATGATGTATTTTCTACTATTGCTGTTAATTTGCATTGTTAAAAATTCTTAAAGTTTAATATGTTATGTTCAGTCATTGAA
AGCGACCACTCATTTTTTTCTTAAAGTTGATGCCTTTTCTGCTGTGCTAGAGTCAGTATTTTGCTTCTGGCAGGAGAGCTGCAAACTGTG
TATCCTCAAACAGATGCAAAAAGTAGTGCTTTGCAAAACGTTTGTTTTCTGTTTATCTCAGATTAACATCCTTTAATACAAGTTTCTTAA
GTGTAACTTGTATTTCTGAAAATGCTTAAAATTATTTTATATTTCCCTTTGGGAATTTTTCTCTATTTCCAGCACGCTGATTTGATTTAA
AAATGTAATAAGACCAAGAGTTGGAGTAAAGGGATATTCATTCCATGTTAAAAGTGGCTTCATAGCTACTGACAAATGTCTGAACTATTG
TCGTGCCCTTCAAAACTGGAGTTTTCTAAAATAATCTTATTTTTATACTTGTATGTTCCAGCAATTTAAGATATATACCATTGAAAGGGA

>351_351_21_ABCG1-BACE2_ABCG1_chr21_43708422_ENST00000398457_BACE2_chr21_42598193_ENST00000347667_length(amino acids)=781AA_BP=417
MCQELFLMLGTQGWTKQRKPCPQNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLNGHLKKVDNNLTEAQRFSSLPRRAAVNIEFRD
LSYSVPEGPWWRKKGYKTLLKGISGKFNSGELVAIMGPSGAGKSTLMNILAGYRETGMKGAVLINGLPRDLRCFRKVSCYIMQDDMLLPH
LTVQEAMMVSAHLKLQEKDEGRREMVKEILTALGLLSCANTRTGSLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMKG
LAQGGRSIICTIHQPSAKLFELFDQLYVLSQGQCVYRGKVCNLVPYLRDLGLNCPTYHNPADFVMEVASGEYGDQNSRLVRAVREGMCDS
DHKRDLGGDAEVNPFLWHRPSEEDSSSMEGCHSFSASCLTQFCILFKRTFLSIMRDSLQILVDTGSSNFAVAGTPHSYIDTYFDTERSST
YRSKGFDVTVKYTQGSWTGFVGEDLVTIPKGFNTSFLVNIATIFESENFFLPGIKWNGILGLAYATLAKPSSSLETFFDSLVTQANIPNV
FSMQMCGAGLPVAGSGTNGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVFD
AVVEAVARASLLYIQPMMGAGLNYECYRFGISPSTNALVIGATVMEGFYVIFDRAQKRVGFAASPCAEIAGAAVSEISGPFSTEDVASNC

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Fusion Gene PPI Analysis for ABCG1-BACE2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ABCG1-BACE2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ABCG1-BACE2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneABCG1C0009402Colorectal Carcinoma1CTD_human
HgeneABCG1C0009404Colorectal Neoplasms1CTD_human
HgeneABCG1C0022661Kidney Failure, Chronic1CTD_human
HgeneABCG1C0023893Liver Cirrhosis, Experimental1CTD_human
HgeneABCG1C0043094Weight Gain1CTD_human