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Center for Computational Systems Medicine level1
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:KAZN-PRDM2

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: KAZN-PRDM2
FusionPDB ID: 41288
FusionGDB2.0 ID: 41288
HgeneTgene
Gene symbol

KAZN

PRDM2

Gene ID

23254

7799

Gene namekazrin, periplakin interacting proteinPR/SET domain 2
SynonymsC1orf196|KAZHUMHOXY1|KMT8|KMT8A|MTB-ZF|RIZ|RIZ1|RIZ2
Cytomap

1p36.21

1p36.21

Type of geneprotein-codingprotein-coding
DescriptionkazrinPR domain zinc finger protein 2GATA-3 binding protein G3BMTE-binding proteinPR domain 2PR domain containing 2, with ZNF domainPR domain-containing protein 2lysine N-methyltransferase 8retinoblastoma protein-binding zinc finger proteinretinoblastom
Modification date2020031320200313
UniProtAcc

Q674X7

.
Ensembl transtripts involved in fusion geneENST idsENST00000361144, ENST00000376030, 
ENST00000400797, ENST00000400798, 
ENST00000422387, ENST00000503743, 
ENST00000235372, ENST00000311066, 
ENST00000343137, ENST00000413440, 
ENST00000502727, ENST00000503842, 
ENST00000505823, ENST00000376048, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score15 X 11 X 8=132010 X 8 X 4=320
# samples 1811
** MAII scorelog2(18/1320*10)=-2.87446911791614
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/320*10)=-1.5405683813627
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: KAZN [Title/Abstract] AND PRDM2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)KAZN(15287371)-PRDM2(14142921), # samples:2
Anticipated loss of major functional domain due to fusion event.KAZN-PRDM2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
KAZN-PRDM2 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
KAZN-PRDM2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
KAZN-PRDM2 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgenePRDM2

GO:0045944

positive regulation of transcription by RNA polymerase II

8654390


check buttonFusion gene breakpoints across KAZN (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PRDM2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4THCATCGA-EM-A4FUKAZNchr1

15287371

+PRDM2chr1

14142921

+


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000376030KAZNchr115287371+ENST00000376048PRDM2chr114142921+2763712150881243
ENST00000503743KAZNchr115287371+ENST00000376048PRDM2chr114142921+2678627137796219
ENST00000422387KAZNchr115287371+ENST00000376048PRDM2chr114142921+2750699137868243
ENST00000361144KAZNchr115287371+ENST00000376048PRDM2chr114142921+26866356031201
ENST00000400798KAZNchr115287371+ENST00000376048PRDM2chr114142921+248843719606195
ENST00000400797KAZNchr115287371+ENST00000376048PRDM2chr114142921+249844716541286122

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000376030ENST00000376048KAZNchr115287371+PRDM2chr114142921+0.0158592870.98414075
ENST00000503743ENST00000376048KAZNchr115287371+PRDM2chr114142921+0.0126870950.98731285
ENST00000422387ENST00000376048KAZNchr115287371+PRDM2chr114142921+0.0135553250.98644465
ENST00000361144ENST00000376048KAZNchr115287371+PRDM2chr114142921+0.156923590.84307635
ENST00000400798ENST00000376048KAZNchr115287371+PRDM2chr114142921+0.58984390.41015613
ENST00000400797ENST00000376048KAZNchr115287371+PRDM2chr114142921+0.175020650.82497936

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>41288_41288_1_KAZN-PRDM2_KAZN_chr1_15287371_ENST00000361144_PRDM2_chr1_14142921_ENST00000376048_length(amino acids)=201AA_BP=
MLLLGQLDPELGGREDLRGLAALRLLQVLRQHLLHLPEKVNFLLEPRHFFPQEHGLAAVAIRSDPGNPGAGPIAGPRRVHALLAGCGSRG
PRGPGPRPAGRRRLALRRELADALPRARVGRPHAGCPGGRYQRLREGLRRRAPGSQTRRSPPHRGAAEPAPASRPAGGARRTRALSPAGR

--------------------------------------------------------------

>41288_41288_2_KAZN-PRDM2_KAZN_chr1_15287371_ENST00000376030_PRDM2_chr1_14142921_ENST00000376048_length(amino acids)=243AA_BP=187
MPVPGGRGAGEAGPRRTQQVEPGVPGRAPPAHHAALCHLSRPQAKILSMMEDNKQLALRIDGAVQSASQEVTNLRAELTATNRRLAELSG
GGGPGPGPGAAASASAAGDSAATNMENPQLGAQVLLREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELA

--------------------------------------------------------------

>41288_41288_3_KAZN-PRDM2_KAZN_chr1_15287371_ENST00000400797_PRDM2_chr1_14142921_ENST00000376048_length(amino acids)=122AA_BP=
MPGVCPKGTKPKNLTELGPNAKLSSPVSPRHGLTVLQRAGVSPVRPWQDGLRNLFFFPLCFLIFPFFFHFPICFFPIAANLRSSDTKDVH

--------------------------------------------------------------

>41288_41288_4_KAZN-PRDM2_KAZN_chr1_15287371_ENST00000400798_PRDM2_chr1_14142921_ENST00000376048_length(amino acids)=195AA_BP=139
MPPVHKDNLCLPCGGFYEGGDSRLSLVCFLDAFKRGQLEDINCGNSPEPSSDGISPSCAAVAPSLEEIRNQKSVTVLLREEVSRLQEEVH
LLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQATASAWRPDALHQRPRTSPGSIGRSKLQLQPSSRDHSSKSR

--------------------------------------------------------------

>41288_41288_5_KAZN-PRDM2_KAZN_chr1_15287371_ENST00000422387_PRDM2_chr1_14142921_ENST00000376048_length(amino acids)=243AA_BP=187
MPVPGGRGAGEAGPRRTQQVEPGVPGRAPPAHHAALCHLSRPQAKILSMMEDNKQLALRIDGAVQSASQEVTNLRAELTATNRRLAELSG
GGGPGPGPGAAASASAAGDSAATNMENPQLGAQVLLREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELA

--------------------------------------------------------------

>41288_41288_6_KAZN-PRDM2_KAZN_chr1_15287371_ENST00000503743_PRDM2_chr1_14142921_ENST00000376048_length(amino acids)=219AA_BP=163
MPVPGGRGAGEAGPRRTQQAKILSMMEDNKQLALRIDGAVQSASQEVTNLRAELTATNRRLAELSGGGGPGPGPGAAASASAAGDSAATN
MENPQLGAQVLLREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQATASAWRPDALHQRPRT

--------------------------------------------------------------

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Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:15287371/chr1:14142921)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
KAZN

Q674X7

.
FUNCTION: Component of the cornified envelope of keratinocytes. May be involved in the interplay between adherens junctions and desmosomes. The function in the nucleus is not known. {ECO:0000269|PubMed:15337775}.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgenePRDM2chr1:15287371chr1:14142921ENST00000311066091052_107401683.0Compositional biasNote=Poly-Ser
TgenePRDM2chr1:15287371chr1:14142921ENST00000311066091361_144701683.0Compositional biasNote=Arg/Lys-rich (basic)
TgenePRDM2chr1:15287371chr1:14142921ENST0000031106609268_29601683.0Compositional biasNote=Asp/Glu-rich (acidic)
TgenePRDM2chr1:15287371chr1:14142921ENST0000031106609933_104901683.0Compositional biasNote=Pro-rich
TgenePRDM2chr1:15287371chr1:14142921ENST00000376048581052_1074170.33333333333334227.0Compositional biasNote=Poly-Ser
TgenePRDM2chr1:15287371chr1:14142921ENST00000376048581361_1447170.33333333333334227.0Compositional biasNote=Arg/Lys-rich (basic)
TgenePRDM2chr1:15287371chr1:14142921ENST0000037604858268_296170.33333333333334227.0Compositional biasNote=Asp/Glu-rich (acidic)
TgenePRDM2chr1:15287371chr1:14142921ENST0000037604858933_1049170.33333333333334227.0Compositional biasNote=Pro-rich
TgenePRDM2chr1:15287371chr1:14142921ENST000003110660928_14101683.0DomainSET
TgenePRDM2chr1:15287371chr1:14142921ENST00000311066091028_105201683.0MotifSH3-binding
TgenePRDM2chr1:15287371chr1:14142921ENST0000031106609970_97901683.0MotifSH3-binding
TgenePRDM2chr1:15287371chr1:14142921ENST0000031106609985_99801683.0MotifSH3-binding
TgenePRDM2chr1:15287371chr1:14142921ENST00000376048581028_1052170.33333333333334227.0MotifSH3-binding
TgenePRDM2chr1:15287371chr1:14142921ENST0000037604858970_979170.33333333333334227.0MotifSH3-binding
TgenePRDM2chr1:15287371chr1:14142921ENST0000037604858985_998170.33333333333334227.0MotifSH3-binding
TgenePRDM2chr1:15287371chr1:14142921ENST0000031106609294_31601683.0RegionNote=Retinoblastoma protein binding
TgenePRDM2chr1:15287371chr1:14142921ENST0000037604858294_316170.33333333333334227.0RegionNote=Retinoblastoma protein binding
TgenePRDM2chr1:15287371chr1:14142921ENST00000311066091134_115601683.0Zinc fingerC2H2-type 4
TgenePRDM2chr1:15287371chr1:14142921ENST00000311066091162_118501683.0Zinc fingerC2H2-type 5
TgenePRDM2chr1:15287371chr1:14142921ENST00000311066091191_121401683.0Zinc fingerC2H2-type 6
TgenePRDM2chr1:15287371chr1:14142921ENST00000311066091333_135501683.0Zinc fingerC2H2-type 7%3B atypical
TgenePRDM2chr1:15287371chr1:14142921ENST00000311066091455_147801683.0Zinc fingerC2H2-type 8%3B atypical
TgenePRDM2chr1:15287371chr1:14142921ENST0000031106609360_38201683.0Zinc fingerC2H2-type 1
TgenePRDM2chr1:15287371chr1:14142921ENST0000031106609390_41201683.0Zinc fingerC2H2-type 2
TgenePRDM2chr1:15287371chr1:14142921ENST0000031106609483_50601683.0Zinc fingerC2H2-type 3
TgenePRDM2chr1:15287371chr1:14142921ENST00000376048581134_1156170.33333333333334227.0Zinc fingerC2H2-type 4
TgenePRDM2chr1:15287371chr1:14142921ENST00000376048581162_1185170.33333333333334227.0Zinc fingerC2H2-type 5
TgenePRDM2chr1:15287371chr1:14142921ENST00000376048581191_1214170.33333333333334227.0Zinc fingerC2H2-type 6
TgenePRDM2chr1:15287371chr1:14142921ENST00000376048581333_1355170.33333333333334227.0Zinc fingerC2H2-type 7%3B atypical
TgenePRDM2chr1:15287371chr1:14142921ENST00000376048581455_1478170.33333333333334227.0Zinc fingerC2H2-type 8%3B atypical
TgenePRDM2chr1:15287371chr1:14142921ENST0000037604858360_382170.33333333333334227.0Zinc fingerC2H2-type 1
TgenePRDM2chr1:15287371chr1:14142921ENST0000037604858390_412170.33333333333334227.0Zinc fingerC2H2-type 2
TgenePRDM2chr1:15287371chr1:14142921ENST0000037604858483_506170.33333333333334227.0Zinc fingerC2H2-type 3

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKAZNchr1:15287371chr1:14142921ENST00000361144+2874_256133.33333333333334416.0Coiled coilOntology_term=ECO:0000255
HgeneKAZNchr1:15287371chr1:14142921ENST00000376030+21574_256139.33333333333334776.0Coiled coilOntology_term=ECO:0000255
HgeneKAZNchr1:15287371chr1:14142921ENST00000400797+2874_25645.333333333333336328.0Coiled coilOntology_term=ECO:0000255
HgeneKAZNchr1:15287371chr1:14142921ENST00000400798+2874_25645.333333333333336328.0Coiled coilOntology_term=ECO:0000255
HgeneKAZNchr1:15287371chr1:14142921ENST00000422387+2874_256139.33333333333334422.0Coiled coilOntology_term=ECO:0000255
HgeneKAZNchr1:15287371chr1:14142921ENST00000503743+3974_256139.33333333333334422.0Coiled coilOntology_term=ECO:0000255
HgeneKAZNchr1:15287371chr1:14142921ENST00000361144+28375_382133.33333333333334416.0Compositional biasNote=Poly-Lys
HgeneKAZNchr1:15287371chr1:14142921ENST00000376030+215375_382139.33333333333334776.0Compositional biasNote=Poly-Lys
HgeneKAZNchr1:15287371chr1:14142921ENST00000400797+28375_38245.333333333333336328.0Compositional biasNote=Poly-Lys
HgeneKAZNchr1:15287371chr1:14142921ENST00000400798+28375_38245.333333333333336328.0Compositional biasNote=Poly-Lys
HgeneKAZNchr1:15287371chr1:14142921ENST00000422387+28375_382139.33333333333334422.0Compositional biasNote=Poly-Lys
HgeneKAZNchr1:15287371chr1:14142921ENST00000503743+39375_382139.33333333333334422.0Compositional biasNote=Poly-Lys
HgeneKAZNchr1:15287371chr1:14142921ENST00000361144+28446_511133.33333333333334416.0DomainSAM 1
HgeneKAZNchr1:15287371chr1:14142921ENST00000361144+28524_588133.33333333333334416.0DomainSAM 2
HgeneKAZNchr1:15287371chr1:14142921ENST00000361144+28612_679133.33333333333334416.0DomainSAM 3
HgeneKAZNchr1:15287371chr1:14142921ENST00000376030+215446_511139.33333333333334776.0DomainSAM 1
HgeneKAZNchr1:15287371chr1:14142921ENST00000376030+215524_588139.33333333333334776.0DomainSAM 2
HgeneKAZNchr1:15287371chr1:14142921ENST00000376030+215612_679139.33333333333334776.0DomainSAM 3
HgeneKAZNchr1:15287371chr1:14142921ENST00000400797+28446_51145.333333333333336328.0DomainSAM 1
HgeneKAZNchr1:15287371chr1:14142921ENST00000400797+28524_58845.333333333333336328.0DomainSAM 2
HgeneKAZNchr1:15287371chr1:14142921ENST00000400797+28612_67945.333333333333336328.0DomainSAM 3
HgeneKAZNchr1:15287371chr1:14142921ENST00000400798+28446_51145.333333333333336328.0DomainSAM 1
HgeneKAZNchr1:15287371chr1:14142921ENST00000400798+28524_58845.333333333333336328.0DomainSAM 2
HgeneKAZNchr1:15287371chr1:14142921ENST00000400798+28612_67945.333333333333336328.0DomainSAM 3
HgeneKAZNchr1:15287371chr1:14142921ENST00000422387+28446_511139.33333333333334422.0DomainSAM 1
HgeneKAZNchr1:15287371chr1:14142921ENST00000422387+28524_588139.33333333333334422.0DomainSAM 2
HgeneKAZNchr1:15287371chr1:14142921ENST00000422387+28612_679139.33333333333334422.0DomainSAM 3
HgeneKAZNchr1:15287371chr1:14142921ENST00000503743+39446_511139.33333333333334422.0DomainSAM 1
HgeneKAZNchr1:15287371chr1:14142921ENST00000503743+39524_588139.33333333333334422.0DomainSAM 2
HgeneKAZNchr1:15287371chr1:14142921ENST00000503743+39612_679139.33333333333334422.0DomainSAM 3
TgenePRDM2chr1:15287371chr1:14142921ENST000002353727101052_10741678.66666666666672095.6666666666665Compositional biasNote=Poly-Ser
TgenePRDM2chr1:15287371chr1:14142921ENST000002353727101361_14471678.66666666666672095.6666666666665Compositional biasNote=Arg/Lys-rich (basic)
TgenePRDM2chr1:15287371chr1:14142921ENST00000235372710268_2961678.66666666666672095.6666666666665Compositional biasNote=Asp/Glu-rich (acidic)
TgenePRDM2chr1:15287371chr1:14142921ENST00000235372710933_10491678.66666666666672095.6666666666665Compositional biasNote=Pro-rich
TgenePRDM2chr1:15287371chr1:14142921ENST0000023537271028_1411678.66666666666672095.6666666666665DomainSET
TgenePRDM2chr1:15287371chr1:14142921ENST000003760485828_141170.33333333333334227.0DomainSET
TgenePRDM2chr1:15287371chr1:14142921ENST000002353727101028_10521678.66666666666672095.6666666666665MotifSH3-binding
TgenePRDM2chr1:15287371chr1:14142921ENST00000235372710970_9791678.66666666666672095.6666666666665MotifSH3-binding
TgenePRDM2chr1:15287371chr1:14142921ENST00000235372710985_9981678.66666666666672095.6666666666665MotifSH3-binding
TgenePRDM2chr1:15287371chr1:14142921ENST00000235372710294_3161678.66666666666672095.6666666666665RegionNote=Retinoblastoma protein binding
TgenePRDM2chr1:15287371chr1:14142921ENST000002353727101134_11561678.66666666666672095.6666666666665Zinc fingerC2H2-type 4
TgenePRDM2chr1:15287371chr1:14142921ENST000002353727101162_11851678.66666666666672095.6666666666665Zinc fingerC2H2-type 5
TgenePRDM2chr1:15287371chr1:14142921ENST000002353727101191_12141678.66666666666672095.6666666666665Zinc fingerC2H2-type 6
TgenePRDM2chr1:15287371chr1:14142921ENST000002353727101333_13551678.66666666666672095.6666666666665Zinc fingerC2H2-type 7%3B atypical
TgenePRDM2chr1:15287371chr1:14142921ENST000002353727101455_14781678.66666666666672095.6666666666665Zinc fingerC2H2-type 8%3B atypical
TgenePRDM2chr1:15287371chr1:14142921ENST00000235372710360_3821678.66666666666672095.6666666666665Zinc fingerC2H2-type 1
TgenePRDM2chr1:15287371chr1:14142921ENST00000235372710390_4121678.66666666666672095.6666666666665Zinc fingerC2H2-type 2
TgenePRDM2chr1:15287371chr1:14142921ENST00000235372710483_5061678.66666666666672095.6666666666665Zinc fingerC2H2-type 3


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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
KAZN
PRDM2


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneKAZNchr1:15287371chr1:14142921ENST00000361144+28174_333133.33333333333334416.0PPL
HgeneKAZNchr1:15287371chr1:14142921ENST00000376030+215174_333139.33333333333334776.0PPL
HgeneKAZNchr1:15287371chr1:14142921ENST00000400797+28174_33345.333333333333336328.0PPL
HgeneKAZNchr1:15287371chr1:14142921ENST00000400798+28174_33345.333333333333336328.0PPL
HgeneKAZNchr1:15287371chr1:14142921ENST00000422387+28174_333139.33333333333334422.0PPL
HgeneKAZNchr1:15287371chr1:14142921ENST00000503743+39174_333139.33333333333334422.0PPL


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Related Drugs to KAZN-PRDM2


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to KAZN-PRDM2


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource