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Fusion Protein:MGAT5-SP100 |
Fusion Protein Summary |
 Fusion gene summary |
| Fusion partner gene information | Fusion gene name: MGAT5-SP100 | FusionPDB ID: 53360 | FusionGDB2.0 ID: 53360 | Hgene | Tgene | Gene symbol | MGAT5 | SP100 | Gene ID | 4249 | 6672 |
| Gene name | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase | SP100 nuclear antigen | |
| Synonyms | GNT-V|GNT-VA|MGAT5A|glcNAc-T V | lysp100b | |
| Cytomap | 2q21.2-q21.3 | 2q37.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase AN-acetylglucosaminyl-transferase Valpha-mannoside beta-1,6-N-acetylglucosaminyltransferasealpha-mannoside beta-1,6-N-acetylglucosaminyltransferase Vmannoside acetylglucosaminyltran | nuclear autoantigen Sp-100SP100-HMG nuclear autoantigennuclear dot-associated Sp100 proteinspeckled 100 kDa | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | Q3V5L5 | . | |
| Ensembl transtripts involved in fusion gene | ENST ids | ENST00000468758, ENST00000281923, ENST00000409645, | ENST00000264052, ENST00000340126, ENST00000341950, ENST00000409112, ENST00000409341, ENST00000409824, ENST00000409897, ENST00000427101, |
| Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0) | * DoF score | 11 X 12 X 3=396 | 3 X 3 X 2=18 |
| # samples | 14 | 4 | |
| ** MAII score | log2(14/396*10)=-1.50007360313464 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/18*10)=1.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context (manual curation of fusion genes in FusionPDB) | PubMed: MGAT5 [Title/Abstract] AND SP100 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0) | MGAT5(135012215)-SP100(231327150), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | MGAT5-SP100 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. MGAT5-SP100 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. MGAT5-SP100 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. MGAT5-SP100 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. MGAT5-SP100 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF. MGAT5-SP100 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF. MGAT5-SP100 seems lost the major protein functional domain in Tgene partner, which is a epigenetic factor due to the frame-shifted ORF. MGAT5-SP100 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF. MGAT5-SP100 seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF. MGAT5-SP100 seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | MGAT5 | GO:0006487 | protein N-linked glycosylation | 24846175 |
| Hgene | MGAT5 | GO:0018279 | protein N-linked glycosylation via asparagine | 10395745|30140003 |
| Hgene | MGAT5 | GO:0030335 | positive regulation of cell migration | 24846175 |
| Hgene | MGAT5 | GO:1903614 | negative regulation of protein tyrosine phosphatase activity | 24846175 |
| Hgene | MGAT5 | GO:1904894 | positive regulation of STAT cascade | 24846175 |
| Tgene | SP100 | GO:0000122 | negative regulation of transcription by RNA polymerase II | 15247905 |
| Tgene | SP100 | GO:0006978 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator | 14647468 |
| Tgene | SP100 | GO:0034340 | response to type I interferon | 9230084|15247905 |
| Tgene | SP100 | GO:0034341 | response to interferon-gamma | 9230084 |
| Tgene | SP100 | GO:0043392 | negative regulation of DNA binding | 15247905 |
| Tgene | SP100 | GO:0043433 | negative regulation of DNA-binding transcription factor activity | 15247905 |
| Tgene | SP100 | GO:0045185 | maintenance of protein location | 12470659 |
| Fusion gene breakpoints across MGAT5 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across SP100 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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Fusion Gene Sample Information |
| Fusion gene information from FusionGDB2.0. |
| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | STAD | TCGA-HU-A4GJ-01A | MGAT5 | chr2 | 135012215 | + | SP100 | chr2 | 231327150 | + |
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Fusion ORF Analysis |
| Fusion information from ORFfinder translation from full-length transcript sequence from FusionPDB. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000409645 | MGAT5 | chr2 | 135012215 | + | ENST00000264052 | SP100 | chr2 | 231327150 | + | 3047 | 493 | 252 | 2159 | 635 |
| ENST00000409645 | MGAT5 | chr2 | 135012215 | + | ENST00000409112 | SP100 | chr2 | 231327150 | + | 1687 | 493 | 252 | 1586 | 444 |
| ENST00000409645 | MGAT5 | chr2 | 135012215 | + | ENST00000340126 | SP100 | chr2 | 231327150 | + | 2415 | 493 | 252 | 2177 | 641 |
| ENST00000409645 | MGAT5 | chr2 | 135012215 | + | ENST00000427101 | SP100 | chr2 | 231327150 | + | 1363 | 493 | 252 | 953 | 233 |
| ENST00000409645 | MGAT5 | chr2 | 135012215 | + | ENST00000409824 | SP100 | chr2 | 231327150 | + | 1340 | 493 | 252 | 962 | 236 |
| ENST00000409645 | MGAT5 | chr2 | 135012215 | + | ENST00000409341 | SP100 | chr2 | 231327150 | + | 1368 | 493 | 252 | 962 | 236 |
| ENST00000409645 | MGAT5 | chr2 | 135012215 | + | ENST00000341950 | SP100 | chr2 | 231327150 | + | 942 | 493 | 252 | 941 | 229 |
| ENST00000409645 | MGAT5 | chr2 | 135012215 | + | ENST00000409897 | SP100 | chr2 | 231327150 | + | 1381 | 493 | 252 | 962 | 236 |
| ENST00000281923 | MGAT5 | chr2 | 135012215 | + | ENST00000264052 | SP100 | chr2 | 231327150 | + | 2940 | 386 | 145 | 2052 | 635 |
| ENST00000281923 | MGAT5 | chr2 | 135012215 | + | ENST00000409112 | SP100 | chr2 | 231327150 | + | 1580 | 386 | 145 | 1479 | 444 |
| ENST00000281923 | MGAT5 | chr2 | 135012215 | + | ENST00000340126 | SP100 | chr2 | 231327150 | + | 2308 | 386 | 145 | 2070 | 641 |
| ENST00000281923 | MGAT5 | chr2 | 135012215 | + | ENST00000427101 | SP100 | chr2 | 231327150 | + | 1256 | 386 | 145 | 846 | 233 |
| ENST00000281923 | MGAT5 | chr2 | 135012215 | + | ENST00000409824 | SP100 | chr2 | 231327150 | + | 1233 | 386 | 145 | 855 | 236 |
| ENST00000281923 | MGAT5 | chr2 | 135012215 | + | ENST00000409341 | SP100 | chr2 | 231327150 | + | 1261 | 386 | 145 | 855 | 236 |
| ENST00000281923 | MGAT5 | chr2 | 135012215 | + | ENST00000341950 | SP100 | chr2 | 231327150 | + | 835 | 386 | 145 | 834 | 230 |
| ENST00000281923 | MGAT5 | chr2 | 135012215 | + | ENST00000409897 | SP100 | chr2 | 231327150 | + | 1274 | 386 | 145 | 855 | 236 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000409645 | ENST00000264052 | MGAT5 | chr2 | 135012215 | + | SP100 | chr2 | 231327150 | + | 0.0009897 | 0.9990103 |
| ENST00000409645 | ENST00000409112 | MGAT5 | chr2 | 135012215 | + | SP100 | chr2 | 231327150 | + | 0.008976928 | 0.99102306 |
| ENST00000409645 | ENST00000340126 | MGAT5 | chr2 | 135012215 | + | SP100 | chr2 | 231327150 | + | 0.003545954 | 0.9964541 |
| ENST00000409645 | ENST00000427101 | MGAT5 | chr2 | 135012215 | + | SP100 | chr2 | 231327150 | + | 0.003296366 | 0.9967037 |
| ENST00000409645 | ENST00000409824 | MGAT5 | chr2 | 135012215 | + | SP100 | chr2 | 231327150 | + | 0.004365132 | 0.99563485 |
| ENST00000409645 | ENST00000409341 | MGAT5 | chr2 | 135012215 | + | SP100 | chr2 | 231327150 | + | 0.004185962 | 0.995814 |
| ENST00000409645 | ENST00000341950 | MGAT5 | chr2 | 135012215 | + | SP100 | chr2 | 231327150 | + | 0.007266083 | 0.99273396 |
| ENST00000409645 | ENST00000409897 | MGAT5 | chr2 | 135012215 | + | SP100 | chr2 | 231327150 | + | 0.004068144 | 0.9959319 |
| ENST00000281923 | ENST00000264052 | MGAT5 | chr2 | 135012215 | + | SP100 | chr2 | 231327150 | + | 0.000852339 | 0.99914765 |
| ENST00000281923 | ENST00000409112 | MGAT5 | chr2 | 135012215 | + | SP100 | chr2 | 231327150 | + | 0.007357612 | 0.99264234 |
| ENST00000281923 | ENST00000340126 | MGAT5 | chr2 | 135012215 | + | SP100 | chr2 | 231327150 | + | 0.003314668 | 0.9966853 |
| ENST00000281923 | ENST00000427101 | MGAT5 | chr2 | 135012215 | + | SP100 | chr2 | 231327150 | + | 0.00368984 | 0.9963102 |
| ENST00000281923 | ENST00000409824 | MGAT5 | chr2 | 135012215 | + | SP100 | chr2 | 231327150 | + | 0.005155684 | 0.9948443 |
| ENST00000281923 | ENST00000409341 | MGAT5 | chr2 | 135012215 | + | SP100 | chr2 | 231327150 | + | 0.005113911 | 0.9948861 |
| ENST00000281923 | ENST00000341950 | MGAT5 | chr2 | 135012215 | + | SP100 | chr2 | 231327150 | + | 0.009890941 | 0.9901091 |
| ENST00000281923 | ENST00000409897 | MGAT5 | chr2 | 135012215 | + | SP100 | chr2 | 231327150 | + | 0.005144892 | 0.99485505 |
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Fusion Amino Acid Sequences |
| For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP >53360_53360_1_MGAT5-SP100_MGAT5_chr2_135012215_ENST00000281923_SP100_chr2_231327150_ENST00000264052_length(amino acids)=635AA_BP=80 MALFTPWKLSSQKLGFFLVTFGFIWGMMLLHFTIQQRTQPESSSMLREQILDLSKRYIKALAEENRNVVDGPYAGVMTAYVISSEDSEGS TDVDEPLEVFISAPRSEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESFKKRVIGQDHDFSESSEEEAPAEASSGALR SKHGEKAPMTSRSTSTWRIPSRKRRFSSSDFSDLSNGEELQETCSSSLRRGSGSQPQEPENKKCSCVMCFPKGVPRSQEARTESSQASDM MDTMDVENNSTLEKHSGKRRKKRRHRSKVNGLQRGRKKDRPRKHLTLNNKVQKKRWQQRGRKANTRPLKRRRKRGPRIPKDENINFKQSE LPVTCGEVKGTLYKERFKQGTSKKCIQSEDKKWFTPREFEIEGDRGASKNWKLSIRCGGYTLKVLMENKFLPEPPSTRKKRILESHNNTL VDPCEEHKKKNPDASVKFSEFLKKCSETWKTIFAKEKGKFEDMAKADKAHYEREMKTYIPPKGEKKKKFKDPNAPKRPPLAFFLFCSEYR PKIKGEHPGLSIDDVVKKLAGMWNNTAAADKQFYEKKAAKLKEKYKKDIAAYRAKGKPNSAKKRVVKAEKSKKKKEEEEDEEDEQEEENE -------------------------------------------------------------- >53360_53360_2_MGAT5-SP100_MGAT5_chr2_135012215_ENST00000281923_SP100_chr2_231327150_ENST00000340126_length(amino acids)=641AA_BP=80 MALFTPWKLSSQKLGFFLVTFGFIWGMMLLHFTIQQRTQPESSSMLREQILDLSKRYIKALAEENRNVVDGPYAGVMTAYVISSEDSEGS TDVDEPLEVFISAPRSEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESFKKRVIGQDHDFSESSEEEAPAEASSGALR SKHGEKAPMTSRSTSTWRIPSRKRRFSSSDFSDLSNGEELQETCSSSLRRGSGSQPQEPENKKCSCVMCFPKGVPRSQEARTESSQASDM MDTMDVENNSTLEKHSGKRRKKRRHRSKVNGLQRGRKKDRPRKHLTLNNKVQKKRWQQRGRKANTRPLKRRRKRGPRIPKDENINFKQSE LPVTCGEVKGTLYKERFKQGTSKKCIQSEDKKWFTPREFEIEGDRGASKNWKLSIRCGGYTLKVLMENKFLPEPPSTRKKRILESHNNTL VDPCPENSNICEVCNKWGRLFCCDTCPRSFHEHCHIPSVEANKNPWSCIFCRIKTIQERCPESQSGHQESEVLMRQMLPEEQLKCEFLLL KVYCDSKSCFFASEPYYNREGSQGPQKPMWLNKVKTSLNEQMYTRVEGFVQDMRLIFHNHKEFYREDKFTRLGIQVQDIFEKNFRNIFAI -------------------------------------------------------------- >53360_53360_3_MGAT5-SP100_MGAT5_chr2_135012215_ENST00000281923_SP100_chr2_231327150_ENST00000341950_length(amino acids)=230AA_BP=80 MALFTPWKLSSQKLGFFLVTFGFIWGMMLLHFTIQQRTQPESSSMLREQILDLSKRYIKALAEENRNVVDGPYAGVMTAYVISSEDSEGS TDVDEPLEVFISAPRSEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESFKKRVIGQDHDFSESSEEEAPAEASSGALR -------------------------------------------------------------- >53360_53360_4_MGAT5-SP100_MGAT5_chr2_135012215_ENST00000281923_SP100_chr2_231327150_ENST00000409112_length(amino acids)=444AA_BP=80 MALFTPWKLSSQKLGFFLVTFGFIWGMMLLHFTIQQRTQPESSSMLREQILDLSKRYIKALAEENRNVVDGPYAGVMTAYVISSEDSEGS TDVDEPLEVFISAPRSEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESFKKRVIGQDHDFSESSEEEAPAEASSGALR SKHGEKAPMTSRSTSTWRIPSRKRRFSSSDFSDLSNGEELQETCSSSLRRGSGSQPQEPENKKCSCVMCFPKGVPRSQEARTESSQASDM MDTMDVENNSTLEKHSGKRRKKRRHRSKVNGLQRGRKKDRPRKHLTLNNKVQKKRWQQRGRKANTRPLKRRRKRGPRIPKDENINFKQSE -------------------------------------------------------------- >53360_53360_5_MGAT5-SP100_MGAT5_chr2_135012215_ENST00000281923_SP100_chr2_231327150_ENST00000409341_length(amino acids)=236AA_BP=80 MALFTPWKLSSQKLGFFLVTFGFIWGMMLLHFTIQQRTQPESSSMLREQILDLSKRYIKALAEENRNVVDGPYAGVMTAYVISSEDSEGS TDVDEPLEVFISAPRSEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESFKKRVIGQDHDFSESSEEEAPAEASSGALR -------------------------------------------------------------- >53360_53360_6_MGAT5-SP100_MGAT5_chr2_135012215_ENST00000281923_SP100_chr2_231327150_ENST00000409824_length(amino acids)=236AA_BP=80 MALFTPWKLSSQKLGFFLVTFGFIWGMMLLHFTIQQRTQPESSSMLREQILDLSKRYIKALAEENRNVVDGPYAGVMTAYVISSEDSEGS TDVDEPLEVFISAPRSEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESFKKRVIGQDHDFSESSEEEAPAEASSGALR -------------------------------------------------------------- >53360_53360_7_MGAT5-SP100_MGAT5_chr2_135012215_ENST00000281923_SP100_chr2_231327150_ENST00000409897_length(amino acids)=236AA_BP=80 MALFTPWKLSSQKLGFFLVTFGFIWGMMLLHFTIQQRTQPESSSMLREQILDLSKRYIKALAEENRNVVDGPYAGVMTAYVISSEDSEGS TDVDEPLEVFISAPRSEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESFKKRVIGQDHDFSESSEEEAPAEASSGALR -------------------------------------------------------------- >53360_53360_8_MGAT5-SP100_MGAT5_chr2_135012215_ENST00000281923_SP100_chr2_231327150_ENST00000427101_length(amino acids)=233AA_BP=80 MALFTPWKLSSQKLGFFLVTFGFIWGMMLLHFTIQQRTQPESSSMLREQILDLSKRYIKALAEENRNVVDGPYAGVMTAYVISSEDSEGS TDVDEPLEVFISAPRSEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESFKKRVIGQDHDFSESSEEEAPAEASSGALR -------------------------------------------------------------- >53360_53360_9_MGAT5-SP100_MGAT5_chr2_135012215_ENST00000409645_SP100_chr2_231327150_ENST00000264052_length(amino acids)=635AA_BP=80 MALFTPWKLSSQKLGFFLVTFGFIWGMMLLHFTIQQRTQPESSSMLREQILDLSKRYIKALAEENRNVVDGPYAGVMTAYVISSEDSEGS TDVDEPLEVFISAPRSEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESFKKRVIGQDHDFSESSEEEAPAEASSGALR SKHGEKAPMTSRSTSTWRIPSRKRRFSSSDFSDLSNGEELQETCSSSLRRGSGSQPQEPENKKCSCVMCFPKGVPRSQEARTESSQASDM MDTMDVENNSTLEKHSGKRRKKRRHRSKVNGLQRGRKKDRPRKHLTLNNKVQKKRWQQRGRKANTRPLKRRRKRGPRIPKDENINFKQSE LPVTCGEVKGTLYKERFKQGTSKKCIQSEDKKWFTPREFEIEGDRGASKNWKLSIRCGGYTLKVLMENKFLPEPPSTRKKRILESHNNTL VDPCEEHKKKNPDASVKFSEFLKKCSETWKTIFAKEKGKFEDMAKADKAHYEREMKTYIPPKGEKKKKFKDPNAPKRPPLAFFLFCSEYR PKIKGEHPGLSIDDVVKKLAGMWNNTAAADKQFYEKKAAKLKEKYKKDIAAYRAKGKPNSAKKRVVKAEKSKKKKEEEEDEEDEQEEENE -------------------------------------------------------------- >53360_53360_10_MGAT5-SP100_MGAT5_chr2_135012215_ENST00000409645_SP100_chr2_231327150_ENST00000340126_length(amino acids)=641AA_BP=80 MALFTPWKLSSQKLGFFLVTFGFIWGMMLLHFTIQQRTQPESSSMLREQILDLSKRYIKALAEENRNVVDGPYAGVMTAYVISSEDSEGS TDVDEPLEVFISAPRSEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESFKKRVIGQDHDFSESSEEEAPAEASSGALR SKHGEKAPMTSRSTSTWRIPSRKRRFSSSDFSDLSNGEELQETCSSSLRRGSGSQPQEPENKKCSCVMCFPKGVPRSQEARTESSQASDM MDTMDVENNSTLEKHSGKRRKKRRHRSKVNGLQRGRKKDRPRKHLTLNNKVQKKRWQQRGRKANTRPLKRRRKRGPRIPKDENINFKQSE LPVTCGEVKGTLYKERFKQGTSKKCIQSEDKKWFTPREFEIEGDRGASKNWKLSIRCGGYTLKVLMENKFLPEPPSTRKKRILESHNNTL VDPCPENSNICEVCNKWGRLFCCDTCPRSFHEHCHIPSVEANKNPWSCIFCRIKTIQERCPESQSGHQESEVLMRQMLPEEQLKCEFLLL KVYCDSKSCFFASEPYYNREGSQGPQKPMWLNKVKTSLNEQMYTRVEGFVQDMRLIFHNHKEFYREDKFTRLGIQVQDIFEKNFRNIFAI -------------------------------------------------------------- >53360_53360_11_MGAT5-SP100_MGAT5_chr2_135012215_ENST00000409645_SP100_chr2_231327150_ENST00000341950_length(amino acids)=229AA_BP=80 MALFTPWKLSSQKLGFFLVTFGFIWGMMLLHFTIQQRTQPESSSMLREQILDLSKRYIKALAEENRNVVDGPYAGVMTAYVISSEDSEGS TDVDEPLEVFISAPRSEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESFKKRVIGQDHDFSESSEEEAPAEASSGALR -------------------------------------------------------------- >53360_53360_12_MGAT5-SP100_MGAT5_chr2_135012215_ENST00000409645_SP100_chr2_231327150_ENST00000409112_length(amino acids)=444AA_BP=80 MALFTPWKLSSQKLGFFLVTFGFIWGMMLLHFTIQQRTQPESSSMLREQILDLSKRYIKALAEENRNVVDGPYAGVMTAYVISSEDSEGS TDVDEPLEVFISAPRSEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESFKKRVIGQDHDFSESSEEEAPAEASSGALR SKHGEKAPMTSRSTSTWRIPSRKRRFSSSDFSDLSNGEELQETCSSSLRRGSGSQPQEPENKKCSCVMCFPKGVPRSQEARTESSQASDM MDTMDVENNSTLEKHSGKRRKKRRHRSKVNGLQRGRKKDRPRKHLTLNNKVQKKRWQQRGRKANTRPLKRRRKRGPRIPKDENINFKQSE -------------------------------------------------------------- >53360_53360_13_MGAT5-SP100_MGAT5_chr2_135012215_ENST00000409645_SP100_chr2_231327150_ENST00000409341_length(amino acids)=236AA_BP=80 MALFTPWKLSSQKLGFFLVTFGFIWGMMLLHFTIQQRTQPESSSMLREQILDLSKRYIKALAEENRNVVDGPYAGVMTAYVISSEDSEGS TDVDEPLEVFISAPRSEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESFKKRVIGQDHDFSESSEEEAPAEASSGALR -------------------------------------------------------------- >53360_53360_14_MGAT5-SP100_MGAT5_chr2_135012215_ENST00000409645_SP100_chr2_231327150_ENST00000409824_length(amino acids)=236AA_BP=80 MALFTPWKLSSQKLGFFLVTFGFIWGMMLLHFTIQQRTQPESSSMLREQILDLSKRYIKALAEENRNVVDGPYAGVMTAYVISSEDSEGS TDVDEPLEVFISAPRSEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESFKKRVIGQDHDFSESSEEEAPAEASSGALR -------------------------------------------------------------- >53360_53360_15_MGAT5-SP100_MGAT5_chr2_135012215_ENST00000409645_SP100_chr2_231327150_ENST00000409897_length(amino acids)=236AA_BP=80 MALFTPWKLSSQKLGFFLVTFGFIWGMMLLHFTIQQRTQPESSSMLREQILDLSKRYIKALAEENRNVVDGPYAGVMTAYVISSEDSEGS TDVDEPLEVFISAPRSEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESFKKRVIGQDHDFSESSEEEAPAEASSGALR -------------------------------------------------------------- >53360_53360_16_MGAT5-SP100_MGAT5_chr2_135012215_ENST00000409645_SP100_chr2_231327150_ENST00000427101_length(amino acids)=233AA_BP=80 MALFTPWKLSSQKLGFFLVTFGFIWGMMLLHFTIQQRTQPESSSMLREQILDLSKRYIKALAEENRNVVDGPYAGVMTAYVISSEDSEGS TDVDEPLEVFISAPRSEPVINNDNPLESNDEKEGQEATCSRPQIVPEPMDFRKLSTFRESFKKRVIGQDHDFSESSEEEAPAEASSGALR -------------------------------------------------------------- |
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Fusion Protein Functional Features |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:135012215/chr2:231327150) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MGAT5 | . |
| FUNCTION: Glycosyltransferase that acts on alpha-linked mannose of N-glycans and O-mannosyl glycans. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to the beta 1-6 linkage of the mannose residue of GlcNAc-beta1,2-Man-alpha on both the alpha1,3- and alpha1,6-linked mannose arms in the core structure of N-glycan. Also acts on the GlcNAc-beta1,2-Man-alpha1-Ser/Thr moiety, forming a 2,6-branched structure in brain O-mannosyl glycan. Plays an active role in modulating integrin and laminin-dependent adhesion and migration of neuronal cells via its activity in the O-mannosyl glycan pathway. {ECO:0000269|PubMed:12941944, ECO:0000269|PubMed:14617637, ECO:0000269|PubMed:14623122, ECO:0000269|PubMed:16606368, ECO:0000269|PubMed:16857188, ECO:0000269|PubMed:19846580}. | FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - Retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | MGAT5 | chr2:135012215 | chr2:231327150 | ENST00000281923 | + | 1 | 16 | 1_13 | 80.33333333333333 | 742.0 | Topological domain | Cytoplasmic |
| Hgene | MGAT5 | chr2:135012215 | chr2:231327150 | ENST00000409645 | + | 2 | 17 | 1_13 | 80.33333333333333 | 742.0 | Topological domain | Cytoplasmic |
| Hgene | MGAT5 | chr2:135012215 | chr2:231327150 | ENST00000281923 | + | 1 | 16 | 14_30 | 80.33333333333333 | 742.0 | Transmembrane | Helical%3B Signal-anchor for type II membrane protein |
| Hgene | MGAT5 | chr2:135012215 | chr2:231327150 | ENST00000409645 | + | 2 | 17 | 14_30 | 80.33333333333333 | 742.0 | Transmembrane | Helical%3B Signal-anchor for type II membrane protein |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000264052 | 8 | 25 | 759_764 | 324.3333333333333 | 880.0 | Compositional bias | Note=Poly-Lys | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000264052 | 8 | 25 | 854_859 | 324.3333333333333 | 880.0 | Compositional bias | Note=Poly-Lys | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000264052 | 8 | 25 | 860_868 | 324.3333333333333 | 880.0 | Compositional bias | Note=Poly-Glu | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000340126 | 8 | 29 | 759_764 | 324.3333333333333 | 886.0 | Compositional bias | Note=Poly-Lys | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000340126 | 8 | 29 | 854_859 | 324.3333333333333 | 886.0 | Compositional bias | Note=Poly-Lys | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000340126 | 8 | 29 | 860_868 | 324.3333333333333 | 886.0 | Compositional bias | Note=Poly-Glu | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000409341 | 8 | 15 | 759_764 | 324.3333333333333 | 481.0 | Compositional bias | Note=Poly-Lys | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000409341 | 8 | 15 | 854_859 | 324.3333333333333 | 481.0 | Compositional bias | Note=Poly-Lys | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000409341 | 8 | 15 | 860_868 | 324.3333333333333 | 481.0 | Compositional bias | Note=Poly-Glu | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000409897 | 9 | 16 | 759_764 | 289.3333333333333 | 446.0 | Compositional bias | Note=Poly-Lys | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000409897 | 9 | 16 | 854_859 | 289.3333333333333 | 446.0 | Compositional bias | Note=Poly-Lys | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000409897 | 9 | 16 | 860_868 | 289.3333333333333 | 446.0 | Compositional bias | Note=Poly-Glu | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000427101 | 7 | 14 | 759_764 | 299.3333333333333 | 453.0 | Compositional bias | Note=Poly-Lys | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000427101 | 7 | 14 | 854_859 | 299.3333333333333 | 453.0 | Compositional bias | Note=Poly-Lys | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000427101 | 7 | 14 | 860_868 | 299.3333333333333 | 453.0 | Compositional bias | Note=Poly-Glu | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000264052 | 8 | 25 | 677_753 | 324.3333333333333 | 880.0 | DNA binding | HMG box 1 | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000264052 | 8 | 25 | 769_837 | 324.3333333333333 | 880.0 | DNA binding | HMG box 2 | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000340126 | 8 | 29 | 677_753 | 324.3333333333333 | 886.0 | DNA binding | HMG box 1 | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000340126 | 8 | 29 | 769_837 | 324.3333333333333 | 886.0 | DNA binding | HMG box 2 | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000409341 | 8 | 15 | 677_753 | 324.3333333333333 | 481.0 | DNA binding | HMG box 1 | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000409341 | 8 | 15 | 769_837 | 324.3333333333333 | 481.0 | DNA binding | HMG box 2 | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000409897 | 9 | 16 | 677_753 | 289.3333333333333 | 446.0 | DNA binding | HMG box 1 | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000409897 | 9 | 16 | 769_837 | 289.3333333333333 | 446.0 | DNA binding | HMG box 2 | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000427101 | 7 | 14 | 677_753 | 299.3333333333333 | 453.0 | DNA binding | HMG box 1 | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000427101 | 7 | 14 | 769_837 | 299.3333333333333 | 453.0 | DNA binding | HMG box 2 | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000264052 | 8 | 25 | 595_676 | 324.3333333333333 | 880.0 | Domain | SAND | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000340126 | 8 | 29 | 595_676 | 324.3333333333333 | 886.0 | Domain | SAND | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000409341 | 8 | 15 | 595_676 | 324.3333333333333 | 481.0 | Domain | SAND | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000409897 | 9 | 16 | 595_676 | 289.3333333333333 | 446.0 | Domain | SAND | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000427101 | 7 | 14 | 595_676 | 299.3333333333333 | 453.0 | Domain | SAND | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000264052 | 8 | 25 | 536_553 | 324.3333333333333 | 880.0 | Motif | Nuclear localization signal | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000264052 | 8 | 25 | 568_592 | 324.3333333333333 | 880.0 | Motif | Nuclear localization signal | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000264052 | 8 | 25 | 717_734 | 324.3333333333333 | 880.0 | Motif | Nuclear localization signal | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000340126 | 8 | 29 | 536_553 | 324.3333333333333 | 886.0 | Motif | Nuclear localization signal | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000340126 | 8 | 29 | 568_592 | 324.3333333333333 | 886.0 | Motif | Nuclear localization signal | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000340126 | 8 | 29 | 717_734 | 324.3333333333333 | 886.0 | Motif | Nuclear localization signal | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000409341 | 8 | 15 | 536_553 | 324.3333333333333 | 481.0 | Motif | Nuclear localization signal | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000409341 | 8 | 15 | 568_592 | 324.3333333333333 | 481.0 | Motif | Nuclear localization signal | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000409341 | 8 | 15 | 717_734 | 324.3333333333333 | 481.0 | Motif | Nuclear localization signal | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000409897 | 9 | 16 | 536_553 | 289.3333333333333 | 446.0 | Motif | Nuclear localization signal | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000409897 | 9 | 16 | 568_592 | 289.3333333333333 | 446.0 | Motif | Nuclear localization signal | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000409897 | 9 | 16 | 717_734 | 289.3333333333333 | 446.0 | Motif | Nuclear localization signal | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000427101 | 7 | 14 | 536_553 | 299.3333333333333 | 453.0 | Motif | Nuclear localization signal | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000427101 | 7 | 14 | 568_592 | 299.3333333333333 | 453.0 | Motif | Nuclear localization signal | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000427101 | 7 | 14 | 717_734 | 299.3333333333333 | 453.0 | Motif | Nuclear localization signal |
| - Not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | MGAT5 | chr2:135012215 | chr2:231327150 | ENST00000281923 | + | 1 | 16 | 213_741 | 80.33333333333333 | 742.0 | Region | Sufficient for catalytic activity |
| Hgene | MGAT5 | chr2:135012215 | chr2:231327150 | ENST00000281923 | + | 1 | 16 | 264_269 | 80.33333333333333 | 742.0 | Region | Important for activity in FGF2 release |
| Hgene | MGAT5 | chr2:135012215 | chr2:231327150 | ENST00000281923 | + | 1 | 16 | 378_379 | 80.33333333333333 | 742.0 | Region | Substrate binding |
| Hgene | MGAT5 | chr2:135012215 | chr2:231327150 | ENST00000409645 | + | 2 | 17 | 213_741 | 80.33333333333333 | 742.0 | Region | Sufficient for catalytic activity |
| Hgene | MGAT5 | chr2:135012215 | chr2:231327150 | ENST00000409645 | + | 2 | 17 | 264_269 | 80.33333333333333 | 742.0 | Region | Important for activity in FGF2 release |
| Hgene | MGAT5 | chr2:135012215 | chr2:231327150 | ENST00000409645 | + | 2 | 17 | 378_379 | 80.33333333333333 | 742.0 | Region | Substrate binding |
| Hgene | MGAT5 | chr2:135012215 | chr2:231327150 | ENST00000281923 | + | 1 | 16 | 31_741 | 80.33333333333333 | 742.0 | Topological domain | Lumenal |
| Hgene | MGAT5 | chr2:135012215 | chr2:231327150 | ENST00000409645 | + | 2 | 17 | 31_741 | 80.33333333333333 | 742.0 | Topological domain | Lumenal |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000264052 | 8 | 25 | 156_164 | 324.3333333333333 | 880.0 | Compositional bias | Note=Poly-Glu | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000264052 | 8 | 25 | 3_6 | 324.3333333333333 | 880.0 | Compositional bias | Note=Poly-Gly | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000340126 | 8 | 29 | 156_164 | 324.3333333333333 | 886.0 | Compositional bias | Note=Poly-Glu | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000340126 | 8 | 29 | 3_6 | 324.3333333333333 | 886.0 | Compositional bias | Note=Poly-Gly | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000409341 | 8 | 15 | 156_164 | 324.3333333333333 | 481.0 | Compositional bias | Note=Poly-Glu | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000409341 | 8 | 15 | 3_6 | 324.3333333333333 | 481.0 | Compositional bias | Note=Poly-Gly | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000409897 | 9 | 16 | 156_164 | 289.3333333333333 | 446.0 | Compositional bias | Note=Poly-Glu | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000409897 | 9 | 16 | 3_6 | 289.3333333333333 | 446.0 | Compositional bias | Note=Poly-Gly | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000427101 | 7 | 14 | 156_164 | 299.3333333333333 | 453.0 | Compositional bias | Note=Poly-Glu | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000427101 | 7 | 14 | 3_6 | 299.3333333333333 | 453.0 | Compositional bias | Note=Poly-Gly | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000264052 | 8 | 25 | 33_149 | 324.3333333333333 | 880.0 | Domain | HSR | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000340126 | 8 | 29 | 33_149 | 324.3333333333333 | 886.0 | Domain | HSR | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000409341 | 8 | 15 | 33_149 | 324.3333333333333 | 481.0 | Domain | HSR | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000409897 | 9 | 16 | 33_149 | 289.3333333333333 | 446.0 | Domain | HSR | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000427101 | 7 | 14 | 33_149 | 299.3333333333333 | 453.0 | Domain | HSR | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000264052 | 8 | 25 | 165_168 | 324.3333333333333 | 880.0 | Motif | Note=D-box%3B recognition signal for CDC20-mediated degradation | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000264052 | 8 | 25 | 284_297 | 324.3333333333333 | 880.0 | Motif | Note=PxVxL motif | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000340126 | 8 | 29 | 165_168 | 324.3333333333333 | 886.0 | Motif | Note=D-box%3B recognition signal for CDC20-mediated degradation | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000340126 | 8 | 29 | 284_297 | 324.3333333333333 | 886.0 | Motif | Note=PxVxL motif | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000409341 | 8 | 15 | 165_168 | 324.3333333333333 | 481.0 | Motif | Note=D-box%3B recognition signal for CDC20-mediated degradation | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000409341 | 8 | 15 | 284_297 | 324.3333333333333 | 481.0 | Motif | Note=PxVxL motif | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000409897 | 9 | 16 | 165_168 | 289.3333333333333 | 446.0 | Motif | Note=D-box%3B recognition signal for CDC20-mediated degradation | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000409897 | 9 | 16 | 284_297 | 289.3333333333333 | 446.0 | Motif | Note=PxVxL motif | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000427101 | 7 | 14 | 165_168 | 299.3333333333333 | 453.0 | Motif | Note=D-box%3B recognition signal for CDC20-mediated degradation | |
| Tgene | SP100 | chr2:135012215 | chr2:231327150 | ENST00000427101 | 7 | 14 | 284_297 | 299.3333333333333 | 453.0 | Motif | Note=PxVxL motif |
Top |
Fusion Protein-Protein Interaction |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160) |
| Gene | PPI interactors |
| Protein-protein interactors based on sequence similarity (STRING) |
| Gene | STRING network |
| MGAT5 | |
| SP100 |
| - Retained interactions in fusion protein (protein functional feature from UniProt). |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost interactions due to fusion (protein functional feature from UniProt). |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
Related Drugs to MGAT5-SP100 |
| Drugs used for this fusion-positive patient. (Manual curation of PubMed, 04-30-2022 + MyCancerGenome) |
| Hgene | Tgene | Drug | Source | PMID |
Top |
Related Diseases to MGAT5-SP100 |
| Diseases that have this fusion gene. (Manual curation of PubMed, 04-30-2022 + MyCancerGenome) |
| Hgene | Tgene | Disease | Source | PMID |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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