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Center for Computational Systems Medicine level1
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:PTCH1-TPM1

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: PTCH1-TPM1
FusionPDB ID: 69869
FusionGDB2.0 ID: 69869
HgeneTgene
Gene symbol

PTCH1

TPM1

Gene ID

5727

7168

Gene namepatched 1tropomyosin 1
SynonymsBCNS|NBCCS|PTC|PTC1|PTCHC15orf13|CMD1Y|CMH3|HEL-S-265|HTM-alpha|LVNC9|TMSA
Cytomap

9q22.32

15q22.2

Type of geneprotein-codingprotein-coding
Descriptionprotein patched homolog 1tropomyosin alpha-1 chaincardiomyopathy, hypertrophic 3epididymis secretory protein Li 265sarcomeric tropomyosin kappa
Modification date2020031420200320
UniProtAcc..
Ensembl transtripts involved in fusion geneENST idsENST00000331920, ENST00000375274, 
ENST00000418258, ENST00000421141, 
ENST00000429896, ENST00000430669, 
ENST00000437951, ENST00000468211, 
ENST00000548379, 
ENST00000267996, 
ENST00000317516, ENST00000334895, 
ENST00000357980, ENST00000403994, 
ENST00000404484, ENST00000559281, 
ENST00000559397, ENST00000559556, 
ENST00000560445, ENST00000560959, 
ENST00000288398, ENST00000358278, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score6 X 7 X 4=16814 X 8 X 8=896
# samples 716
** MAII scorelog2(7/168*10)=-1.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(16/896*10)=-2.48542682717024
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)

PubMed: PTCH1 [Title/Abstract] AND TPM1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)PTCH1(98224138)-TPM1(63349184), # samples:1
Anticipated loss of major functional domain due to fusion event.PTCH1-TPM1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
PTCH1-TPM1 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
PTCH1-TPM1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
PTCH1-TPM1 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
PTCH1-TPM1 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
PTCH1-TPM1 seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgenePTCH1

GO:0010875

positive regulation of cholesterol efflux

21931618

HgenePTCH1

GO:0072659

protein localization to plasma membrane

11278759


check buttonFusion gene breakpoints across PTCH1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across TPM1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-DX-A6B9-01APTCH1chr9

98224138

-TPM1chr15

63349184

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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)
BP loci
(transcript)
Predicted start
(transcript)
Predicted stop
(transcript)
Seq length
(amino acids)
ENST00000418258PTCH1chr998224138-ENST00000288398TPM1chr1563349184+3622276511333791088
ENST00000418258PTCH1chr998224138-ENST00000358278TPM1chr1563349184+4097276511333791088
ENST00000430669PTCH1chr998224138-ENST00000288398TPM1chr1563349184+3948309158637051039
ENST00000430669PTCH1chr998224138-ENST00000358278TPM1chr1563349184+4423309158637051039

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000418258ENST00000288398PTCH1chr998224138-TPM1chr1563349184+0.0016434650.9983565
ENST00000418258ENST00000358278PTCH1chr998224138-TPM1chr1563349184+0.0011510030.99884903
ENST00000430669ENST00000288398PTCH1chr998224138-TPM1chr1563349184+0.0010952710.9989047
ENST00000430669ENST00000358278PTCH1chr998224138-TPM1chr1563349184+0.0007610520.99923897

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>69869_69869_1_PTCH1-TPM1_PTCH1_chr9_98224138_ENST00000418258_TPM1_chr15_63349184_ENST00000288398_length(amino acids)=1088AA_BP=884
MGEPAICCSKERSPLAPVPEGDGQSRTGLLAPEPWAPSLGLRSPSLLSSGGKATGRKAPLWLRAKFQRLLFKLGCYIQKNCGKFLVVGLL
IFGAFAVGLKAANLETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYNRQW
KLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLNKAEV
GHGYMDRPCLNPADPDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHALQTMFQLMTPKQMYEHFK
GYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQG
AVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVT
AFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSS
HSFAHETQITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSLHCLEPPCTKWTLSSFAE
KHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHRSFS
NVKYVMLEENKQLPKMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQAEADVASLNRRIQLVE
EELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELS
EGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDH

--------------------------------------------------------------

>69869_69869_2_PTCH1-TPM1_PTCH1_chr9_98224138_ENST00000418258_TPM1_chr15_63349184_ENST00000358278_length(amino acids)=1088AA_BP=884
MGEPAICCSKERSPLAPVPEGDGQSRTGLLAPEPWAPSLGLRSPSLLSSGGKATGRKAPLWLRAKFQRLLFKLGCYIQKNCGKFLVVGLL
IFGAFAVGLKAANLETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQLMIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYNRQW
KLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTAYLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLNKAEV
GHGYMDRPCLNPADPDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMHWQEELIVGGTVKNSTGKLVSAHALQTMFQLMTPKQMYEHFK
GYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTTTLDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQG
AVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVFLLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVT
AFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDRRLDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSS
HSFAHETQITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDTLSCQSPESTSSTRDLLSQFSDSSLHCLEPPCTKWTLSSFAE
KHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETREYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHRSFS
NVKYVMLEENKQLPKMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNGSDDGVLAYKLLVQTGSRDKPIDISQAEADVASLNRRIQLVE
EELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELS
EGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQ

--------------------------------------------------------------

>69869_69869_3_PTCH1-TPM1_PTCH1_chr9_98224138_ENST00000430669_TPM1_chr15_63349184_ENST00000288398_length(amino acids)=1039AA_BP=835
MGKATGRKAPLWLRAKFQRLLFKLGCYIQKNCGKFLVVGLLIFGAFAVGLKAANLETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQ
LMIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTA
YLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPADPDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMH
WQEELIVGGTVKNSTGKLVSAHALQTMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTTT
LDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVF
LLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDR
RLDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDT
LSCQSPESTSSTRDLLSQFSDSSLHCLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETR
EYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHRSFSNVKYVMLEENKQLPKMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNG
SDDGVLAYKLLVQTGSRDKPIDISQAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQE
IQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEA

--------------------------------------------------------------

>69869_69869_4_PTCH1-TPM1_PTCH1_chr9_98224138_ENST00000430669_TPM1_chr15_63349184_ENST00000358278_length(amino acids)=1039AA_BP=835
MGKATGRKAPLWLRAKFQRLLFKLGCYIQKNCGKFLVVGLLIFGAFAVGLKAANLETNVEELWVEVGGRVSRELNYTRQKIGEEAMFNPQ
LMIQTPKEEGANVLTTEALLQHLDSALQASRVHVYMYNRQWKLEHLCYKSGELITETGYMDQIIEYLYPCLIITPLDCFWEGAKLQSGTA
YLLGKPPLRWTNFDPLEFLEELKKINYQVDSWEEMLNKAEVGHGYMDRPCLNPADPDCPATAPNKNSTKPLDMALVLNGGCHGLSRKYMH
WQEELIVGGTVKNSTGKLVSAHALQTMFQLMTPKQMYEHFKGYEYVSHINWNEDKAAAILEAWQRTYVEVVHQSVAQNSTQKVLSFTTTT
LDDILKSFSDVSVIRVASGYLLMLAYACLTMLRWDCSKSQGAVGLAGVLLVALSVAAGLGLCSLIGISFNAATTQVLPFLALGVGVDDVF
LLAHAFSETGQNKRIPFEDRTGECLKRTGASVALTSISNVTAFFMAALIPIPALRAFSLQAAVVVVFNFAMVLLIFPAILSMDLYRREDR
RLDIFCCFTSPCVSRVIQVEPQAYTDTHDNTRYSPPPPYSSHSFAHETQITMQSTVQLRTEYDPHTHVYYTTAEPRSEISVQPVTVTQDT
LSCQSPESTSSTRDLLSQFSDSSLHCLEPPCTKWTLSSFAEKHYAPFLLKPKAKVVVIFLFLGLLGVSLYGTTRVRDGLDLTDIVPRETR
EYDFIAAQFKYFSFYNMYIVTQKADYPNIQHLLYDLHRSFSNVKYVMLEENKQLPKMWLHYFRDWLQGLQDAFDSDWETGKIMPNNYKNG
SDDGVLAYKLLVQTGSRDKPIDISQAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQE
IQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQLEEQLRIMDQTLKALMAAEDKYSQKEDRYEEEIKVLSDKLKEA

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Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:98224138/chr15:63349184)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePTCH1chr9:98224138chr15:63349184ENST00000331920-162414_31901.02534.3333333333335Compositional biasNote=Gly-rich
HgenePTCH1chr9:98224138chr15:63349184ENST00000375274-162414_31900.01526.3333333333333Compositional biasNote=Gly-rich
HgenePTCH1chr9:98224138chr15:63349184ENST00000418258-162414_31750.02461.3333333333335Compositional biasNote=Gly-rich
HgenePTCH1chr9:98224138chr15:63349184ENST00000421141-162414_31750.02513.3333333333335Compositional biasNote=Gly-rich
HgenePTCH1chr9:98224138chr15:63349184ENST00000429896-162414_31750.02093.3333333333335Compositional biasNote=Gly-rich
HgenePTCH1chr9:98224138chr15:63349184ENST00000430669-162314_31835.01382.0Compositional biasNote=Gly-rich
HgenePTCH1chr9:98224138chr15:63349184ENST00000437951-162414_31835.02468.3333333333335Compositional biasNote=Gly-rich
HgenePTCH1chr9:98224138chr15:63349184ENST00000331920-1624438_598901.02534.3333333333335DomainSSD
HgenePTCH1chr9:98224138chr15:63349184ENST00000375274-1624438_598900.01526.3333333333333DomainSSD
HgenePTCH1chr9:98224138chr15:63349184ENST00000418258-1624438_598750.02461.3333333333335DomainSSD
HgenePTCH1chr9:98224138chr15:63349184ENST00000421141-1624438_598750.02513.3333333333335DomainSSD
HgenePTCH1chr9:98224138chr15:63349184ENST00000429896-1624438_598750.02093.3333333333335DomainSSD
HgenePTCH1chr9:98224138chr15:63349184ENST00000430669-1623438_598835.01382.0DomainSSD
HgenePTCH1chr9:98224138chr15:63349184ENST00000437951-1624438_598835.02468.3333333333335DomainSSD
HgenePTCH1chr9:98224138chr15:63349184ENST00000331920-1624122_436901.02534.3333333333335Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000331920-16241_100901.02534.3333333333335Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000331920-1624458_472901.02534.3333333333335Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000331920-1624494_501901.02534.3333333333335Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000331920-1624523_547901.02534.3333333333335Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000331920-1624569_577901.02534.3333333333335Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000331920-1624599_748901.02534.3333333333335Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000375274-1624122_436900.01526.3333333333333Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000375274-16241_100900.01526.3333333333333Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000375274-1624458_472900.01526.3333333333333Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000375274-1624494_501900.01526.3333333333333Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000375274-1624523_547900.01526.3333333333333Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000375274-1624569_577900.01526.3333333333333Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000375274-1624599_748900.01526.3333333333333Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000418258-1624122_436750.02461.3333333333335Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000418258-16241_100750.02461.3333333333335Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000418258-1624458_472750.02461.3333333333335Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000418258-1624494_501750.02461.3333333333335Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000418258-1624523_547750.02461.3333333333335Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000418258-1624569_577750.02461.3333333333335Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000418258-1624599_748750.02461.3333333333335Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000421141-1624122_436750.02513.3333333333335Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000421141-16241_100750.02513.3333333333335Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000421141-1624458_472750.02513.3333333333335Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000421141-1624494_501750.02513.3333333333335Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000421141-1624523_547750.02513.3333333333335Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000421141-1624569_577750.02513.3333333333335Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000421141-1624599_748750.02513.3333333333335Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000429896-1624122_436750.02093.3333333333335Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000429896-16241_100750.02093.3333333333335Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000429896-1624458_472750.02093.3333333333335Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000429896-1624494_501750.02093.3333333333335Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000429896-1624523_547750.02093.3333333333335Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000429896-1624569_577750.02093.3333333333335Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000429896-1624599_748750.02093.3333333333335Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000430669-1623122_436835.01382.0Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000430669-16231_100835.01382.0Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000430669-1623458_472835.01382.0Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000430669-1623494_501835.01382.0Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000430669-1623523_547835.01382.0Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000430669-1623569_577835.01382.0Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000430669-1623599_748835.01382.0Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000437951-1624122_436835.02468.3333333333335Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000437951-16241_100835.02468.3333333333335Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000437951-1624458_472835.02468.3333333333335Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000437951-1624494_501835.02468.3333333333335Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000437951-1624523_547835.02468.3333333333335Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000437951-1624569_577835.02468.3333333333335Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000437951-1624599_748835.02468.3333333333335Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000331920-1624101_121901.02534.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000331920-1624437_457901.02534.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000331920-1624473_493901.02534.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000331920-1624502_522901.02534.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000331920-1624548_568901.02534.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000331920-1624578_598901.02534.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000331920-1624749_769901.02534.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000375274-1624101_121900.01526.3333333333333TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000375274-1624437_457900.01526.3333333333333TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000375274-1624473_493900.01526.3333333333333TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000375274-1624502_522900.01526.3333333333333TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000375274-1624548_568900.01526.3333333333333TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000375274-1624578_598900.01526.3333333333333TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000375274-1624749_769900.01526.3333333333333TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000418258-1624101_121750.02461.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000418258-1624437_457750.02461.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000418258-1624473_493750.02461.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000418258-1624502_522750.02461.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000418258-1624548_568750.02461.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000418258-1624578_598750.02461.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000421141-1624101_121750.02513.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000421141-1624437_457750.02513.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000421141-1624473_493750.02513.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000421141-1624502_522750.02513.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000421141-1624548_568750.02513.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000421141-1624578_598750.02513.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000429896-1624101_121750.02093.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000429896-1624437_457750.02093.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000429896-1624473_493750.02093.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000429896-1624502_522750.02093.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000429896-1624548_568750.02093.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000429896-1624578_598750.02093.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000430669-1623101_121835.01382.0TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000430669-1623437_457835.01382.0TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000430669-1623473_493835.01382.0TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000430669-1623502_522835.01382.0TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000430669-1623548_568835.01382.0TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000430669-1623578_598835.01382.0TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000430669-1623749_769835.01382.0TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000437951-1624101_121835.02468.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000437951-1624437_457835.02468.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000437951-1624473_493835.02468.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000437951-1624502_522835.02468.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000437951-1624548_568835.02468.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000437951-1624578_598835.02468.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000437951-1624749_769835.02468.3333333333335TransmembraneHelical

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePTCH1chr9:98224138chr15:63349184ENST00000468211-1514_310184.0Compositional biasNote=Gly-rich
HgenePTCH1chr9:98224138chr15:63349184ENST00000468211-15438_5980184.0DomainSSD
HgenePTCH1chr9:98224138chr15:63349184ENST00000331920-16241049_1055901.02534.3333333333335Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000331920-16241077_1083901.02534.3333333333335Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000331920-16241105_1121901.02534.3333333333335Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000331920-16241142_1154901.02534.3333333333335Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000331920-16241176_1447901.02534.3333333333335Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000331920-1624770_1027901.02534.3333333333335Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000375274-16241049_1055900.01526.3333333333333Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000375274-16241077_1083900.01526.3333333333333Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000375274-16241105_1121900.01526.3333333333333Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000375274-16241142_1154900.01526.3333333333333Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000375274-16241176_1447900.01526.3333333333333Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000375274-1624770_1027900.01526.3333333333333Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000418258-16241049_1055750.02461.3333333333335Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000418258-16241077_1083750.02461.3333333333335Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000418258-16241105_1121750.02461.3333333333335Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000418258-16241142_1154750.02461.3333333333335Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000418258-16241176_1447750.02461.3333333333335Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000418258-1624770_1027750.02461.3333333333335Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000421141-16241049_1055750.02513.3333333333335Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000421141-16241077_1083750.02513.3333333333335Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000421141-16241105_1121750.02513.3333333333335Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000421141-16241142_1154750.02513.3333333333335Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000421141-16241176_1447750.02513.3333333333335Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000421141-1624770_1027750.02513.3333333333335Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000429896-16241049_1055750.02093.3333333333335Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000429896-16241077_1083750.02093.3333333333335Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000429896-16241105_1121750.02093.3333333333335Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000429896-16241142_1154750.02093.3333333333335Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000429896-16241176_1447750.02093.3333333333335Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000429896-1624770_1027750.02093.3333333333335Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000430669-16231049_1055835.01382.0Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000430669-16231077_1083835.01382.0Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000430669-16231105_1121835.01382.0Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000430669-16231142_1154835.01382.0Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000430669-16231176_1447835.01382.0Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000430669-1623770_1027835.01382.0Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000437951-16241049_1055835.02468.3333333333335Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000437951-16241077_1083835.02468.3333333333335Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000437951-16241105_1121835.02468.3333333333335Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000437951-16241142_1154835.02468.3333333333335Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000437951-16241176_1447835.02468.3333333333335Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000437951-1624770_1027835.02468.3333333333335Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000468211-151049_10550184.0Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000468211-151077_10830184.0Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000468211-151105_11210184.0Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000468211-151142_11540184.0Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000468211-151176_14470184.0Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000468211-15122_4360184.0Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000468211-151_1000184.0Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000468211-15458_4720184.0Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000468211-15494_5010184.0Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000468211-15523_5470184.0Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000468211-15569_5770184.0Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000468211-15599_7480184.0Topological domainCytoplasmic
HgenePTCH1chr9:98224138chr15:63349184ENST00000468211-15770_10270184.0Topological domainExtracellular
HgenePTCH1chr9:98224138chr15:63349184ENST00000331920-16241028_1048901.02534.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000331920-16241056_1076901.02534.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000331920-16241084_1104901.02534.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000331920-16241122_1141901.02534.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000331920-16241155_1175901.02534.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000375274-16241028_1048900.01526.3333333333333TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000375274-16241056_1076900.01526.3333333333333TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000375274-16241084_1104900.01526.3333333333333TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000375274-16241122_1141900.01526.3333333333333TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000375274-16241155_1175900.01526.3333333333333TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000418258-16241028_1048750.02461.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000418258-16241056_1076750.02461.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000418258-16241084_1104750.02461.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000418258-16241122_1141750.02461.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000418258-16241155_1175750.02461.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000418258-1624749_769750.02461.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000421141-16241028_1048750.02513.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000421141-16241056_1076750.02513.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000421141-16241084_1104750.02513.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000421141-16241122_1141750.02513.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000421141-16241155_1175750.02513.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000421141-1624749_769750.02513.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000429896-16241028_1048750.02093.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000429896-16241056_1076750.02093.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000429896-16241084_1104750.02093.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000429896-16241122_1141750.02093.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000429896-16241155_1175750.02093.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000429896-1624749_769750.02093.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000430669-16231028_1048835.01382.0TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000430669-16231056_1076835.01382.0TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000430669-16231084_1104835.01382.0TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000430669-16231122_1141835.01382.0TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000430669-16231155_1175835.01382.0TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000437951-16241028_1048835.02468.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000437951-16241056_1076835.02468.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000437951-16241084_1104835.02468.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000437951-16241122_1141835.02468.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000437951-16241155_1175835.02468.3333333333335TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000468211-15101_1210184.0TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000468211-151028_10480184.0TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000468211-151056_10760184.0TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000468211-151084_11040184.0TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000468211-151122_11410184.0TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000468211-151155_11750184.0TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000468211-15437_4570184.0TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000468211-15473_4930184.0TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000468211-15502_5220184.0TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000468211-15548_5680184.0TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000468211-15578_5980184.0TransmembraneHelical
HgenePTCH1chr9:98224138chr15:63349184ENST00000468211-15749_7690184.0TransmembraneHelical
TgeneTPM1chr9:98224138chr15:63349184ENST00000267996191_28480.0285.0Coiled coilOntology_term=ECO:0000250
TgeneTPM1chr9:98224138chr15:63349184ENST000002883981101_28480.0247.0Coiled coilOntology_term=ECO:0000250
TgeneTPM1chr9:98224138chr15:63349184ENST00000334895081_28444.0246.0Coiled coilOntology_term=ECO:0000250
TgeneTPM1chr9:98224138chr15:63349184ENST00000358278191_28480.0285.0Coiled coilOntology_term=ECO:0000250
TgeneTPM1chr9:98224138chr15:63349184ENST000004039941101_28480.0285.0Coiled coilOntology_term=ECO:0000250
TgeneTPM1chr9:98224138chr15:63349184ENST00000559397191_28480.0285.0Coiled coilOntology_term=ECO:0000250
TgeneTPM1chr9:98224138chr15:63349184ENST00000559556191_28480.0285.0Coiled coilOntology_term=ECO:0000250


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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
PTCH1
TPM1


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs to PTCH1-TPM1


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to PTCH1-TPM1


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource