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	Fusion Gene Summary
	Fusion Gene Sample Information
	Fusion ORF Analysis
	Fusion Amino Acid Sequences
	Fusion Protein Functional Features
	Fusion Protein-Protein Interaction
	Related drugs with this fusion protein
	Related disease with this fusion protein

Fusion Protein:WWOX-C15orf41

Fusion Protein Summary

Fusion gene summary

Fusion partner gene information	Fusion gene name: WWOX-C15orf41
	FusionPDB ID: 99475
	FusionGDB2.0 ID: 99475
		Hgene	Tgene
	Gene symbol	WWOX	C15orf41
	Gene ID	51741	84529
	Gene name	WW domain containing oxidoreductase	chromosome 15 open reading frame 41
	Synonyms	D16S432E\|EIEE28\|FOR\|FRA16D\|HHCMA56\|PRO0128\|SCAR12\|SDR41C1\|WOX1	HH114
	Cytomap	16q23.1-q23.2	15q14
	Type of gene	protein-coding	protein-coding
	Description	WW domain-containing oxidoreductaseWW domain-containing protein WWOXfragile site FRA16D oxidoreductaseshort chain dehydrogenase/reductase family 41C member 1	protein C15orf41uncharacterized protein C15orf41
	Modification date	20200313	20200313
	UniProtAcc	.	.
Ensembl transtripts involved in fusion gene	ENST ids	ENST00000565791, ENST00000355860, ENST00000406884, ENST00000408984, ENST00000566780, ENST00000402655, ENST00000539474, ENST00000569818,	ENST00000338183, ENST00000437989, ENST00000562877, ENST00000566621, ENST00000567389, ENST00000569302, ENST00000562489, ENST00000563167, ENST00000565792,
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)	* DoF score	26 X 26 X 8=5408	8 X 5 X 7=280
	# samples	31	10
	** MAII score	log2(31/5408*10)=-4.12475503100795 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(10/280*10)=-1.48542682717024 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context (manual curation of fusion genes in FusionPDB)	PubMed: WWOX [Title/Abstract] AND C15orf41 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)	WWOX(78198186)-C15orf41(37100525), # samples:2
Anticipated loss of major functional domain due to fusion event.	WWOX-C15orf41 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. WWOX-C15orf41 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF. WWOX-C15orf41 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. WWOX-C15orf41 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF. WWOX-C15orf41 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF. WWOX-C15orf41 seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF. WWOX-C15orf41 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	WWOX	GO:0030178	negative regulation of Wnt signaling pathway	19465938
Hgene	WWOX	GO:0071560	cellular response to transforming growth factor beta stimulus	19366691

Fusion gene breakpoints across WWOX (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across C15orf41 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

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Fusion Gene Sample Information

Fusion gene information from FusionGDB2.0.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	GBM	TCGA-06-5415-01A	WWOX	chr16	78198186	-	C15orf41	chr15	37100525	+
ChimerDB4	GBM	TCGA-06-5415-01A	WWOX	chr16	78198186	+	C15orf41	chr15	37100525	+

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Fusion ORF Analysis

Fusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000566780	WWOX	chr16	78198186	+	ENST00000566621	C15orf41	chr15	37100525	+	2782	882	366	1118	250
ENST00000566780	WWOX	chr16	78198186	+	ENST00000437989	C15orf41	chr15	37100525	+	2389	882	366	1079	237
ENST00000566780	WWOX	chr16	78198186	+	ENST00000562877	C15orf41	chr15	37100525	+	1012	882	366	1010	215
ENST00000406884	WWOX	chr16	78198186	+	ENST00000566621	C15orf41	chr15	37100525	+	2541	641	125	877	250
ENST00000406884	WWOX	chr16	78198186	+	ENST00000437989	C15orf41	chr15	37100525	+	2148	641	125	838	237
ENST00000406884	WWOX	chr16	78198186	+	ENST00000562877	C15orf41	chr15	37100525	+	771	641	125	769	215
ENST00000408984	WWOX	chr16	78198186	+	ENST00000566621	C15orf41	chr15	37100525	+	2501	601	85	837	250
ENST00000408984	WWOX	chr16	78198186	+	ENST00000437989	C15orf41	chr15	37100525	+	2108	601	85	798	237
ENST00000408984	WWOX	chr16	78198186	+	ENST00000562877	C15orf41	chr15	37100525	+	731	601	85	729	215
ENST00000355860	WWOX	chr16	78198186	+	ENST00000566621	C15orf41	chr15	37100525	+	2516	616	100	852	250
ENST00000355860	WWOX	chr16	78198186	+	ENST00000437989	C15orf41	chr15	37100525	+	2123	616	100	813	237
ENST00000355860	WWOX	chr16	78198186	+	ENST00000562877	C15orf41	chr15	37100525	+	746	616	100	744	215

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000566780	ENST00000566621	WWOX	chr16	78198186	+	C15orf41	chr15	37100525	+	0.004114192	0.9958858
ENST00000566780	ENST00000437989	WWOX	chr16	78198186	+	C15orf41	chr15	37100525	+	0.002894606	0.9971054
ENST00000566780	ENST00000562877	WWOX	chr16	78198186	+	C15orf41	chr15	37100525	+	0.7979124	0.20208761
ENST00000406884	ENST00000566621	WWOX	chr16	78198186	+	C15orf41	chr15	37100525	+	0.00290554	0.9970945
ENST00000406884	ENST00000437989	WWOX	chr16	78198186	+	C15orf41	chr15	37100525	+	0.002347837	0.99765223
ENST00000406884	ENST00000562877	WWOX	chr16	78198186	+	C15orf41	chr15	37100525	+	0.8534378	0.1465622
ENST00000408984	ENST00000566621	WWOX	chr16	78198186	+	C15orf41	chr15	37100525	+	0.002493418	0.99750656
ENST00000408984	ENST00000437989	WWOX	chr16	78198186	+	C15orf41	chr15	37100525	+	0.001856953	0.9981431
ENST00000408984	ENST00000562877	WWOX	chr16	78198186	+	C15orf41	chr15	37100525	+	0.7318975	0.26810247
ENST00000355860	ENST00000566621	WWOX	chr16	78198186	+	C15orf41	chr15	37100525	+	0.002705026	0.99729496
ENST00000355860	ENST00000437989	WWOX	chr16	78198186	+	C15orf41	chr15	37100525	+	0.001838661	0.9981614
ENST00000355860	ENST00000562877	WWOX	chr16	78198186	+	C15orf41	chr15	37100525	+	0.788592	0.211408

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Fusion Amino Acid Sequences

For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>99475_99475_1_WWOX-C15orf41_WWOX_chr16_78198186_ENST00000355860_C15orf41_chr15_37100525_ENST00000437989_length(amino acids)=237AA_BP=159
MAALRYAGLDDTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQVFFVDHINKRTTYLDPRL
AFTVDDNPTKPTTRQRYDGSTTAMEILQGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWIWARLSHL

--------------------------------------------------------------

>99475_99475_2_WWOX-C15orf41_WWOX_chr16_78198186_ENST00000355860_C15orf41_chr15_37100525_ENST00000562877_length(amino acids)=215AA_BP=159
MAALRYAGLDDTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQVFFVDHINKRTTYLDPRL
AFTVDDNPTKPTTRQRYDGSTTAMEILQGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWIWARLSHL

--------------------------------------------------------------

>99475_99475_3_WWOX-C15orf41_WWOX_chr16_78198186_ENST00000355860_C15orf41_chr15_37100525_ENST00000566621_length(amino acids)=250AA_BP=159
MAALRYAGLDDTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQVFFVDHINKRTTYLDPRL
AFTVDDNPTKPTTRQRYDGSTTAMEILQGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWIWARLSHL

--------------------------------------------------------------

>99475_99475_4_WWOX-C15orf41_WWOX_chr16_78198186_ENST00000406884_C15orf41_chr15_37100525_ENST00000437989_length(amino acids)=237AA_BP=159
MAALRYAGLDDTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQVFFVDHINKRTTYLDPRL
AFTVDDNPTKPTTRQRYDGSTTAMEILQGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWIWARLSHL

--------------------------------------------------------------

>99475_99475_5_WWOX-C15orf41_WWOX_chr16_78198186_ENST00000406884_C15orf41_chr15_37100525_ENST00000562877_length(amino acids)=215AA_BP=159
MAALRYAGLDDTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQVFFVDHINKRTTYLDPRL
AFTVDDNPTKPTTRQRYDGSTTAMEILQGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWIWARLSHL

--------------------------------------------------------------

>99475_99475_6_WWOX-C15orf41_WWOX_chr16_78198186_ENST00000406884_C15orf41_chr15_37100525_ENST00000566621_length(amino acids)=250AA_BP=159
MAALRYAGLDDTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQVFFVDHINKRTTYLDPRL
AFTVDDNPTKPTTRQRYDGSTTAMEILQGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWIWARLSHL

--------------------------------------------------------------

>99475_99475_7_WWOX-C15orf41_WWOX_chr16_78198186_ENST00000408984_C15orf41_chr15_37100525_ENST00000437989_length(amino acids)=237AA_BP=159
MAALRYAGLDDTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQVFFVDHINKRTTYLDPRL
AFTVDDNPTKPTTRQRYDGSTTAMEILQGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWIWARLSHL

--------------------------------------------------------------

>99475_99475_8_WWOX-C15orf41_WWOX_chr16_78198186_ENST00000408984_C15orf41_chr15_37100525_ENST00000562877_length(amino acids)=215AA_BP=159
MAALRYAGLDDTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQVFFVDHINKRTTYLDPRL
AFTVDDNPTKPTTRQRYDGSTTAMEILQGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWIWARLSHL

--------------------------------------------------------------

>99475_99475_9_WWOX-C15orf41_WWOX_chr16_78198186_ENST00000408984_C15orf41_chr15_37100525_ENST00000566621_length(amino acids)=250AA_BP=159
MAALRYAGLDDTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQVFFVDHINKRTTYLDPRL
AFTVDDNPTKPTTRQRYDGSTTAMEILQGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWIWARLSHL

--------------------------------------------------------------

>99475_99475_10_WWOX-C15orf41_WWOX_chr16_78198186_ENST00000566780_C15orf41_chr15_37100525_ENST00000437989_length(amino acids)=237AA_BP=159
MAALRYAGLDDTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQVFFVDHINKRTTYLDPRL
AFTVDDNPTKPTTRQRYDGSTTAMEILQGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWIWARLSHL

--------------------------------------------------------------

>99475_99475_11_WWOX-C15orf41_WWOX_chr16_78198186_ENST00000566780_C15orf41_chr15_37100525_ENST00000562877_length(amino acids)=215AA_BP=159
MAALRYAGLDDTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQVFFVDHINKRTTYLDPRL
AFTVDDNPTKPTTRQRYDGSTTAMEILQGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWIWARLSHL

--------------------------------------------------------------

>99475_99475_12_WWOX-C15orf41_WWOX_chr16_78198186_ENST00000566780_C15orf41_chr15_37100525_ENST00000566621_length(amino acids)=250AA_BP=159
MAALRYAGLDDTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQVFFVDHINKRTTYLDPRL
AFTVDDNPTKPTTRQRYDGSTTAMEILQGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWIWARLSHL

--------------------------------------------------------------

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Fusion Protein Functional Features

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:78198186/chr15:37100525)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.	FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page
* Minus value of BPloci means that the break pointn is located before the CDS.

- Retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

WWOX

chr16:78198186

chr15:37100525

ENST00000355860

16_49

172.0

190.0

Domain

WW 1

Hgene

WWOX

chr16:78198186

chr15:37100525

ENST00000355860

57_90

172.0

190.0

Domain

WW 2

Hgene

WWOX

chr16:78198186

chr15:37100525

ENST00000406884

16_49

172.0

235.0

Domain

WW 1

Hgene

WWOX

chr16:78198186

chr15:37100525

ENST00000406884

57_90

172.0

235.0

Domain

WW 2

Hgene

WWOX

chr16:78198186

chr15:37100525

ENST00000408984

16_49

172.0

311.6666666666667

Domain

WW 1

Hgene

WWOX

chr16:78198186

chr15:37100525

ENST00000408984

57_90

172.0

311.6666666666667

Domain

WW 2

Hgene

WWOX

chr16:78198186

chr15:37100525

ENST00000566780

16_49

172.0

415.0

Domain

WW 1

Hgene

WWOX

chr16:78198186

chr15:37100525

ENST00000566780

57_90

172.0

415.0

Domain

WW 2

Hgene

WWOX

chr16:78198186

chr15:37100525

ENST00000355860

50_55

172.0

190.0

Motif

Nuclear localization signal

Hgene

WWOX

chr16:78198186

chr15:37100525

ENST00000406884

50_55

172.0

235.0

Motif

Nuclear localization signal

Hgene

WWOX

chr16:78198186

chr15:37100525

ENST00000408984

50_55

172.0

311.6666666666667

Motif

Nuclear localization signal

Hgene

WWOX

chr16:78198186

chr15:37100525

ENST00000566780

50_55

172.0

415.0

Motif

Nuclear localization signal

Hgene

WWOX

chr16:78198186

chr15:37100525

ENST00000355860

131_137

172.0

190.0

Nucleotide binding

NADP

Hgene

WWOX

chr16:78198186

chr15:37100525

ENST00000406884

131_137

172.0

235.0

Nucleotide binding

NADP

Hgene

WWOX

chr16:78198186

chr15:37100525

ENST00000408984

131_137

172.0

311.6666666666667

Nucleotide binding

NADP

Hgene

WWOX

chr16:78198186

chr15:37100525

ENST00000566780

131_137

172.0

415.0

Nucleotide binding

NADP

- Not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

WWOX

chr16:78198186

chr15:37100525

ENST00000402655

16_49

312.0

Domain

WW 1

Hgene

WWOX

chr16:78198186

chr15:37100525

ENST00000402655

57_90

312.0

Domain

WW 2

Hgene

WWOX

chr16:78198186

chr15:37100525

ENST00000569818

16_49

37.0

Domain

WW 1

Hgene

WWOX

chr16:78198186

chr15:37100525

ENST00000569818

57_90

37.0

Domain

WW 2

Hgene

WWOX

chr16:78198186

chr15:37100525

ENST00000402655

50_55

312.0

Motif

Nuclear localization signal

Hgene

WWOX

chr16:78198186

chr15:37100525

ENST00000569818

50_55

37.0

Motif

Nuclear localization signal

Hgene

WWOX

chr16:78198186

chr15:37100525

ENST00000402655

131_137

312.0

Nucleotide binding

NADP

Hgene

WWOX

chr16:78198186

chr15:37100525

ENST00000569818

131_137

37.0

Nucleotide binding

NADP

Hgene

WWOX

chr16:78198186

chr15:37100525

ENST00000355860

209_273

172.0

190.0

Region

Mediates targeting to the mitochondria

Hgene

WWOX

chr16:78198186

chr15:37100525

ENST00000402655

209_273

312.0

Region

Mediates targeting to the mitochondria

Hgene

WWOX

chr16:78198186

chr15:37100525

ENST00000406884

209_273

172.0

235.0

Region

Mediates targeting to the mitochondria

Hgene

WWOX

chr16:78198186

chr15:37100525

ENST00000408984

209_273

172.0

311.6666666666667

Region

Mediates targeting to the mitochondria

Hgene

WWOX

chr16:78198186

chr15:37100525

ENST00000566780

209_273

172.0

415.0

Region

Mediates targeting to the mitochondria

Hgene

WWOX

chr16:78198186

chr15:37100525

ENST00000569818

209_273

37.0

Region

Mediates targeting to the mitochondria

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Fusion Protein-Protein Interaction

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)

Gene

PPI interactors

Protein-protein interactors based on sequence similarity (STRING)

Gene	STRING network
WWOX
C15orf41

- Retained interactions in fusion protein (protein functional feature from UniProt).

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost interactions due to fusion (protein functional feature from UniProt).

Partner	Gene	Hbp	Tbp	ENST	Strand	BPexon	TotalExon	Protein feature loci	*BPloci	TotalLen	Interaction lost with
Hgene	WWOX	chr16:78198186	chr15:37100525	ENST00000355860	+	5	6	125_414	172.0	190.0	MAPT
Hgene	WWOX	chr16:78198186	chr15:37100525	ENST00000402655	+	1	5	125_414	0	312.0	MAPT
Hgene	WWOX	chr16:78198186	chr15:37100525	ENST00000406884	+	5	6	125_414	172.0	235.0	MAPT
Hgene	WWOX	chr16:78198186	chr15:37100525	ENST00000408984	+	5	10	125_414	172.0	311.6666666666667	MAPT
Hgene	WWOX	chr16:78198186	chr15:37100525	ENST00000566780	+	5	9	125_414	172.0	415.0	MAPT
Hgene	WWOX	chr16:78198186	chr15:37100525	ENST00000569818	+	1	1	125_414	0	37.0	MAPT

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Related Drugs to WWOX-C15orf41

Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Drug

Source

PMID

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Related Diseases to WWOX-C15orf41

Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)

Hgene

Tgene

Disease

Source

PMID

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source