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Center for Computational Systems Medicine level1
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Fusion Gene Summary

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Fusion Gene Sample Information

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Fusion ORF Analysis

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Fusion Amino Acid Sequences

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Fusion Protein Functional Features

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Fusion Protein-Protein Interaction

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Related drugs with this fusion protein

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Related disease with this fusion protein

Fusion Protein:WWOX-NUDT7

Fusion Protein Summary

check button Fusion gene summary
Fusion partner gene informationFusion gene name: WWOX-NUDT7
FusionPDB ID: 99490
FusionGDB2.0 ID: 99490
HgeneTgene
Gene symbol

WWOX

NUDT7

Gene ID

51741

283927

Gene nameWW domain containing oxidoreductasenudix hydrolase 7
SynonymsD16S432E|EIEE28|FOR|FRA16D|HHCMA56|PRO0128|SCAR12|SDR41C1|WOX1-
Cytomap

16q23.1-q23.2

16q23.1

Type of geneprotein-codingprotein-coding
DescriptionWW domain-containing oxidoreductaseWW domain-containing protein WWOXfragile site FRA16D oxidoreductaseshort chain dehydrogenase/reductase family 41C member 1peroxisomal coenzyme A diphosphatase NUDT7nudix (nucleoside diphosphate linked moiety X)-type motif 7
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST idsENST00000355860, ENST00000402655, 
ENST00000406884, ENST00000408984, 
ENST00000539474, ENST00000566780, 
ENST00000565791, ENST00000569818, 
ENST00000564031, ENST00000437314, 
ENST00000563839, ENST00000568787, 
ENST00000268533, ENST00000564085, 
Fusion gene scores for assessment (based on all fusion genes of FusionGDB 2.0)* DoF score26 X 26 X 8=54081 X 1 X 2=2
# samples 312
** MAII scorelog2(31/5408*10)=-4.12475503100795
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(2/2*10)=3.32192809488736
Context (manual curation of fusion genes in FusionPDB)

PubMed: WWOX [Title/Abstract] AND NUDT7 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpoint (based on all fusion genes of FusionGDB 2.0)WWOX(78458952)-NUDT7(77775479), # samples:2
WWOX(78149051)-NUDT7(77775479), # samples:2
Anticipated loss of major functional domain due to fusion event.WWOX-NUDT7 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
WWOX-NUDT7 seems lost the major protein functional domain in Hgene partner, which is a CGC by not retaining the major functional domain in the partially deleted in-frame ORF.
WWOX-NUDT7 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
WWOX-NUDT7 seems lost the major protein functional domain in Hgene partner, which is a essential gene by not retaining the major functional domain in the partially deleted in-frame ORF.
WWOX-NUDT7 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
WWOX-NUDT7 seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF.
WWOX-NUDT7 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneWWOX

GO:0030178

negative regulation of Wnt signaling pathway

19465938

HgeneWWOX

GO:0071560

cellular response to transforming growth factor beta stimulus

19366691


check buttonFusion gene breakpoints across WWOX (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across NUDT7 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


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Fusion Gene Sample Information

check buttonFusion gene information from FusionGDB2.0.
check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-H4-A2HQ-01AWWOXchr16

78458952

+NUDT7chr16

77775479

+
ChimerDB4OVTCGA-24-1842-01AWWOXchr16

78149051

+NUDT7chr16

77775479

+


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Fusion ORF Analysis


check buttonFusion information from ORFfinder translation from full-length transcript sequence from FusionPDB.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000566780WWOXchr1678458952+ENST00000268533NUDT7chr1677775479+183611573661169267
ENST00000408984WWOXchr1678458952+ENST00000268533NUDT7chr1677775479+155587685888267
ENST00000566780WWOXchr1678149051+ENST00000564085NUDT7chr1677775479+1163775366845159
ENST00000406884WWOXchr1678149051+ENST00000564085NUDT7chr1677775479+922534125604159
ENST00000539474WWOXchr1678149051+ENST00000564085NUDT7chr1677775479+922534125604159
ENST00000402655WWOXchr1678149051+ENST00000564085NUDT7chr1677775479+922534125604159
ENST00000408984WWOXchr1678149051+ENST00000564085NUDT7chr1677775479+88249485564159
ENST00000355860WWOXchr1678149051+ENST00000564085NUDT7chr1677775479+897509100579159

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000566780ENST00000268533WWOXchr1678458952+NUDT7chr1677775479+0.003803490.9961965
ENST00000408984ENST00000268533WWOXchr1678458952+NUDT7chr1677775479+0.0018954810.99810445
ENST00000566780ENST00000564085WWOXchr1678149051+NUDT7chr1677775479+0.0079093040.9920907
ENST00000406884ENST00000564085WWOXchr1678149051+NUDT7chr1677775479+0.0064471770.9935528
ENST00000539474ENST00000564085WWOXchr1678149051+NUDT7chr1677775479+0.0064471770.9935528
ENST00000402655ENST00000564085WWOXchr1678149051+NUDT7chr1677775479+0.0064471770.9935528
ENST00000408984ENST00000564085WWOXchr1678149051+NUDT7chr1677775479+0.0046970280.99530303
ENST00000355860ENST00000564085WWOXchr1678149051+NUDT7chr1677775479+0.0047552090.9952448

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Fusion Amino Acid Sequences


check button For individual full-length fusion transcript sequence from FusionPDB, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>FusionGDB ID_FusionGDB isoform ID_FGname_Hgene_Hchr_Hbp_Henst_Tgene_Tchr_Tbp_Tenst_length(fusion AA) seq_BP

>99490_99490_1_WWOX-NUDT7_WWOX_chr16_78149051_ENST00000355860_NUDT7_chr16_77775479_ENST00000564085_length(amino acids)=159AA_BP=136
MAALRYAGLDDTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQVFFVDHINKRTTYLDPRL

--------------------------------------------------------------

>99490_99490_2_WWOX-NUDT7_WWOX_chr16_78149051_ENST00000402655_NUDT7_chr16_77775479_ENST00000564085_length(amino acids)=159AA_BP=136
MAALRYAGLDDTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQVFFVDHINKRTTYLDPRL

--------------------------------------------------------------

>99490_99490_3_WWOX-NUDT7_WWOX_chr16_78149051_ENST00000406884_NUDT7_chr16_77775479_ENST00000564085_length(amino acids)=159AA_BP=136
MAALRYAGLDDTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQVFFVDHINKRTTYLDPRL

--------------------------------------------------------------

>99490_99490_4_WWOX-NUDT7_WWOX_chr16_78149051_ENST00000408984_NUDT7_chr16_77775479_ENST00000564085_length(amino acids)=159AA_BP=136
MAALRYAGLDDTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQVFFVDHINKRTTYLDPRL

--------------------------------------------------------------

>99490_99490_5_WWOX-NUDT7_WWOX_chr16_78149051_ENST00000539474_NUDT7_chr16_77775479_ENST00000564085_length(amino acids)=159AA_BP=136
MAALRYAGLDDTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQVFFVDHINKRTTYLDPRL

--------------------------------------------------------------

>99490_99490_6_WWOX-NUDT7_WWOX_chr16_78149051_ENST00000566780_NUDT7_chr16_77775479_ENST00000564085_length(amino acids)=159AA_BP=136
MAALRYAGLDDTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQVFFVDHINKRTTYLDPRL

--------------------------------------------------------------

>99490_99490_7_WWOX-NUDT7_WWOX_chr16_78458952_ENST00000408984_NUDT7_chr16_77775479_ENST00000268533_length(amino acids)=267AA_BP=
MAALRYAGLDDTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQVFFVDHINKRTTYLDPRL
AFTVDDNPTKPTTRQRYDGSTTAMEILQGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWHKAKVEAM

--------------------------------------------------------------

>99490_99490_8_WWOX-NUDT7_WWOX_chr16_78458952_ENST00000566780_NUDT7_chr16_77775479_ENST00000268533_length(amino acids)=267AA_BP=
MAALRYAGLDDTDSEDELPPGWEERTTKDGWVYYANHTEEKTQWEHPKTGKRKRVAGDLPYGWEQETDENGQVFFVDHINKRTTYLDPRL
AFTVDDNPTKPTTRQRYDGSTTAMEILQGRDFTGKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWHKAKVEAM

--------------------------------------------------------------

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Fusion Protein Functional Features


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:78458952/chr16:77775479)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.FUNCTION: Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

* Minus value of BPloci means that the break pointn is located before the CDS.
- Retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneWWOXchr16:78149051chr16:77775479ENST00000355860+4616_49136.33333333333334190.0DomainWW 1
HgeneWWOXchr16:78149051chr16:77775479ENST00000355860+4657_90136.33333333333334190.0DomainWW 2
HgeneWWOXchr16:78149051chr16:77775479ENST00000402655+4516_49136.33333333333334312.0DomainWW 1
HgeneWWOXchr16:78149051chr16:77775479ENST00000402655+4557_90136.33333333333334312.0DomainWW 2
HgeneWWOXchr16:78149051chr16:77775479ENST00000406884+4616_49136.33333333333334235.0DomainWW 1
HgeneWWOXchr16:78149051chr16:77775479ENST00000406884+4657_90136.33333333333334235.0DomainWW 2
HgeneWWOXchr16:78149051chr16:77775479ENST00000408984+41016_49136.33333333333334311.6666666666667DomainWW 1
HgeneWWOXchr16:78149051chr16:77775479ENST00000408984+41057_90136.33333333333334311.6666666666667DomainWW 2
HgeneWWOXchr16:78149051chr16:77775479ENST00000566780+4916_49136.33333333333334415.0DomainWW 1
HgeneWWOXchr16:78149051chr16:77775479ENST00000566780+4957_90136.33333333333334415.0DomainWW 2
HgeneWWOXchr16:78458952chr16:77775479ENST00000408984+71016_49263.6666666666667311.6666666666667DomainWW 1
HgeneWWOXchr16:78458952chr16:77775479ENST00000408984+71057_90263.6666666666667311.6666666666667DomainWW 2
HgeneWWOXchr16:78458952chr16:77775479ENST00000566780+7916_49263.6666666666667415.0DomainWW 1
HgeneWWOXchr16:78458952chr16:77775479ENST00000566780+7957_90263.6666666666667415.0DomainWW 2
HgeneWWOXchr16:78149051chr16:77775479ENST00000355860+4650_55136.33333333333334190.0MotifNuclear localization signal
HgeneWWOXchr16:78149051chr16:77775479ENST00000402655+4550_55136.33333333333334312.0MotifNuclear localization signal
HgeneWWOXchr16:78149051chr16:77775479ENST00000406884+4650_55136.33333333333334235.0MotifNuclear localization signal
HgeneWWOXchr16:78149051chr16:77775479ENST00000408984+41050_55136.33333333333334311.6666666666667MotifNuclear localization signal
HgeneWWOXchr16:78149051chr16:77775479ENST00000566780+4950_55136.33333333333334415.0MotifNuclear localization signal
HgeneWWOXchr16:78458952chr16:77775479ENST00000408984+71050_55263.6666666666667311.6666666666667MotifNuclear localization signal
HgeneWWOXchr16:78458952chr16:77775479ENST00000566780+7950_55263.6666666666667415.0MotifNuclear localization signal
HgeneWWOXchr16:78149051chr16:77775479ENST00000355860+46131_137136.33333333333334190.0Nucleotide bindingNADP
HgeneWWOXchr16:78149051chr16:77775479ENST00000402655+45131_137136.33333333333334312.0Nucleotide bindingNADP
HgeneWWOXchr16:78149051chr16:77775479ENST00000406884+46131_137136.33333333333334235.0Nucleotide bindingNADP
HgeneWWOXchr16:78149051chr16:77775479ENST00000408984+410131_137136.33333333333334311.6666666666667Nucleotide bindingNADP
HgeneWWOXchr16:78149051chr16:77775479ENST00000566780+49131_137136.33333333333334415.0Nucleotide bindingNADP
HgeneWWOXchr16:78458952chr16:77775479ENST00000408984+710131_137263.6666666666667311.6666666666667Nucleotide bindingNADP
HgeneWWOXchr16:78458952chr16:77775479ENST00000566780+79131_137263.6666666666667415.0Nucleotide bindingNADP
TgeneNUDT7chr16:78149051chr16:77775479ENST0000026853324236_238116.0239.0MotifMicrobody targeting signal
TgeneNUDT7chr16:78149051chr16:77775479ENST0000043731413236_23863.0186.0MotifMicrobody targeting signal
TgeneNUDT7chr16:78149051chr16:77775479ENST000004373141377_9863.0186.0MotifNote=Nudix box
TgeneNUDT7chr16:78458952chr16:77775479ENST0000026853324236_238116.0239.0MotifMicrobody targeting signal
TgeneNUDT7chr16:78458952chr16:77775479ENST0000043731413236_23863.0186.0MotifMicrobody targeting signal
TgeneNUDT7chr16:78458952chr16:77775479ENST000004373141377_9863.0186.0MotifNote=Nudix box

- Not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneWWOXchr16:78149051chr16:77775479ENST00000569818+1116_49037.0DomainWW 1
HgeneWWOXchr16:78149051chr16:77775479ENST00000569818+1157_90037.0DomainWW 2
HgeneWWOXchr16:78458952chr16:77775479ENST00000355860+1616_490190.0DomainWW 1
HgeneWWOXchr16:78458952chr16:77775479ENST00000355860+1657_900190.0DomainWW 2
HgeneWWOXchr16:78458952chr16:77775479ENST00000402655+1516_490312.0DomainWW 1
HgeneWWOXchr16:78458952chr16:77775479ENST00000402655+1557_900312.0DomainWW 2
HgeneWWOXchr16:78458952chr16:77775479ENST00000406884+1616_490235.0DomainWW 1
HgeneWWOXchr16:78458952chr16:77775479ENST00000406884+1657_900235.0DomainWW 2
HgeneWWOXchr16:78458952chr16:77775479ENST00000569818+1116_49037.0DomainWW 1
HgeneWWOXchr16:78458952chr16:77775479ENST00000569818+1157_90037.0DomainWW 2
HgeneWWOXchr16:78149051chr16:77775479ENST00000569818+1150_55037.0MotifNuclear localization signal
HgeneWWOXchr16:78458952chr16:77775479ENST00000355860+1650_550190.0MotifNuclear localization signal
HgeneWWOXchr16:78458952chr16:77775479ENST00000402655+1550_550312.0MotifNuclear localization signal
HgeneWWOXchr16:78458952chr16:77775479ENST00000406884+1650_550235.0MotifNuclear localization signal
HgeneWWOXchr16:78458952chr16:77775479ENST00000569818+1150_55037.0MotifNuclear localization signal
HgeneWWOXchr16:78149051chr16:77775479ENST00000569818+11131_137037.0Nucleotide bindingNADP
HgeneWWOXchr16:78458952chr16:77775479ENST00000355860+16131_1370190.0Nucleotide bindingNADP
HgeneWWOXchr16:78458952chr16:77775479ENST00000402655+15131_1370312.0Nucleotide bindingNADP
HgeneWWOXchr16:78458952chr16:77775479ENST00000406884+16131_1370235.0Nucleotide bindingNADP
HgeneWWOXchr16:78458952chr16:77775479ENST00000569818+11131_137037.0Nucleotide bindingNADP
HgeneWWOXchr16:78149051chr16:77775479ENST00000355860+46209_273136.33333333333334190.0RegionMediates targeting to the mitochondria
HgeneWWOXchr16:78149051chr16:77775479ENST00000402655+45209_273136.33333333333334312.0RegionMediates targeting to the mitochondria
HgeneWWOXchr16:78149051chr16:77775479ENST00000406884+46209_273136.33333333333334235.0RegionMediates targeting to the mitochondria
HgeneWWOXchr16:78149051chr16:77775479ENST00000408984+410209_273136.33333333333334311.6666666666667RegionMediates targeting to the mitochondria
HgeneWWOXchr16:78149051chr16:77775479ENST00000566780+49209_273136.33333333333334415.0RegionMediates targeting to the mitochondria
HgeneWWOXchr16:78149051chr16:77775479ENST00000569818+11209_273037.0RegionMediates targeting to the mitochondria
HgeneWWOXchr16:78458952chr16:77775479ENST00000355860+16209_2730190.0RegionMediates targeting to the mitochondria
HgeneWWOXchr16:78458952chr16:77775479ENST00000402655+15209_2730312.0RegionMediates targeting to the mitochondria
HgeneWWOXchr16:78458952chr16:77775479ENST00000406884+16209_2730235.0RegionMediates targeting to the mitochondria
HgeneWWOXchr16:78458952chr16:77775479ENST00000408984+710209_273263.6666666666667311.6666666666667RegionMediates targeting to the mitochondria
HgeneWWOXchr16:78458952chr16:77775479ENST00000566780+79209_273263.6666666666667415.0RegionMediates targeting to the mitochondria
HgeneWWOXchr16:78458952chr16:77775479ENST00000569818+11209_273037.0RegionMediates targeting to the mitochondria
TgeneNUDT7chr16:78149051chr16:77775479ENST000002685332437_172116.0239.0DomainNudix hydrolase
TgeneNUDT7chr16:78149051chr16:77775479ENST000004373141337_17263.0186.0DomainNudix hydrolase
TgeneNUDT7chr16:78458952chr16:77775479ENST000002685332437_172116.0239.0DomainNudix hydrolase
TgeneNUDT7chr16:78458952chr16:77775479ENST000004373141337_17263.0186.0DomainNudix hydrolase
TgeneNUDT7chr16:78149051chr16:77775479ENST000002685332477_98116.0239.0MotifNote=Nudix box
TgeneNUDT7chr16:78458952chr16:77775479ENST000002685332477_98116.0239.0MotifNote=Nudix box


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Fusion Protein-Protein Interaction


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type from validated records (BIOGRID-3.4.160)
GenePPI interactors


check button Protein-protein interactors based on sequence similarity (STRING)
GeneSTRING network
WWOX
NUDT7


check button - Retained interactions in fusion protein (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost interactions due to fusion (protein functional feature from UniProt).
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneWWOXchr16:78149051chr16:77775479ENST00000355860+46125_414136.33333333333334190.0MAPT
HgeneWWOXchr16:78149051chr16:77775479ENST00000402655+45125_414136.33333333333334312.0MAPT
HgeneWWOXchr16:78149051chr16:77775479ENST00000406884+46125_414136.33333333333334235.0MAPT
HgeneWWOXchr16:78149051chr16:77775479ENST00000408984+410125_414136.33333333333334311.6666666666667MAPT
HgeneWWOXchr16:78149051chr16:77775479ENST00000566780+49125_414136.33333333333334415.0MAPT
HgeneWWOXchr16:78149051chr16:77775479ENST00000569818+11125_414037.0MAPT
HgeneWWOXchr16:78458952chr16:77775479ENST00000355860+16125_4140190.0MAPT
HgeneWWOXchr16:78458952chr16:77775479ENST00000402655+15125_4140312.0MAPT
HgeneWWOXchr16:78458952chr16:77775479ENST00000406884+16125_4140235.0MAPT
HgeneWWOXchr16:78458952chr16:77775479ENST00000408984+710125_414263.6666666666667311.6666666666667MAPT
HgeneWWOXchr16:78458952chr16:77775479ENST00000566780+79125_414263.6666666666667415.0MAPT
HgeneWWOXchr16:78458952chr16:77775479ENST00000569818+11125_414037.0MAPT


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Related Drugs to WWOX-NUDT7


check button Drugs used for this fusion-positive patient.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDrugSourcePMID

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Related Diseases to WWOX-NUDT7


check button Diseases that have this fusion gene.
(Manual curation of PubMed, 04-30-2022 + MyCancerGenome)
HgeneTgeneDiseaseSourcePMID

check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource