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Center for Computational Systems Medicine
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Gene Summary

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Translation studies in PubMed

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Exon Skipping Events

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Expression

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Expression Regulation

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Associated Genes

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Protein 3D Structure

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Protein-Protein Interaction

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Mutations

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Prognostic Analysis

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Gender Association

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Age Association

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Related Drugs

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Related Diseases

Translation Factor: ERBB2 (NCBI Gene ID:2064)


Gene Summary

check button Gene Summary
Gene InformationGene Name: ERBB2
Gene ID: 2064
Gene Symbol

ERBB2

Gene ID

2064

Gene Nameerb-b2 receptor tyrosine kinase 2
SynonymsCD340|HER-2|HER-2/neu|HER2|MLN 19|NEU|NGL|TKR1
Cytomap

17q12

Type of Geneprotein-coding
Descriptionreceptor tyrosine-protein kinase erbB-2c-erb B2/neu proteinherstatinhuman epidermal growth factor receptor 2metastatic lymph node gene 19 proteinneuro/glioblastoma derived oncogene homologneuroblastoma/glioblastoma derived oncogene homologp185erbB2
Modification date20200329
UniProtAcc

P04626


check button Child GO biological process term(s) under GO:0006412
GO IDGO term
GO:0006417Regulation of translation
GO:0045727Positive regulation of translation
GO:0006412Translation


check button Gene ontology of translaction factor with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneERBB2

GO:0007165

signal transduction

10572067

HgeneERBB2

GO:0007166

cell surface receptor signaling pathway

9685399

HgeneERBB2

GO:0007169

transmembrane receptor protein tyrosine kinase signaling pathway

7514177

HgeneERBB2

GO:0014065

phosphatidylinositol 3-kinase signaling

7556068

HgeneERBB2

GO:0018108

peptidyl-tyrosine phosphorylation

12000754

HgeneERBB2

GO:0032886

regulation of microtubule-based process

20937854

HgeneERBB2

GO:0035556

intracellular signal transduction

19372587

HgeneERBB2

GO:0042060

wound healing

12646923

HgeneERBB2

GO:0043406

positive regulation of MAP kinase activity

10572067

HgeneERBB2

GO:0045785

positive regulation of cell adhesion

7556068

HgeneERBB2

GO:0046777

protein autophosphorylation

7556068

HgeneERBB2

GO:0050679

positive regulation of epithelial cell proliferation

10572067

HgeneERBB2

GO:0071363

cellular response to growth factor stimulus

20010870

HgeneERBB2

GO:0090314

positive regulation of protein targeting to membrane

20010870



check button Inferred gene age of translation factor.
GeneInferred gene age group among (0 - 67.6], (67.6 - 355.7], (355.7 - 733], (733 - 1119.25], >1119.25
ERBB2(733 - 1119.25]


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Translation Studies in PubMed

check button We searched PubMed using 'ERBB2[title] AND translation [title] AND human.'
GeneTitlePMID
ERBB2Exosome-mediated lncRNA AFAP1-AS1 promotes trastuzumab resistance through binding with AUF1 and activating ERBB2 translation32020881


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Exon Skipping Events

check buttonSkipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
For more annotations, please visit our ExonSkipDB.
all structure

check button Open reading frame (ORF) analsis of exon skipping events based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ENSTExon skip start (DNA)Exon Skip end (DNA)ORF
ENST000002695713786324237863394Frame-shift
ENST000002695713786557037865705In-frame
ENST000002695713786633837866454Frame-shift
ENST000002695713786857437868701Frame-shift
ENST000002695713787153837871612Frame-shift
ENST000002695713787255337872686Frame-shift
ENST000002695713787603937876087In-frame
ENST000002695713787957137879710Frame-shift
ENST000002695713788016437880263In-frame
ENST000002695713788097837881164In-frame
ENST000002695713788130137881457In-frame
ENST000002695713788195937882106In-frame
ENST000002695713788281437882912Frame-shift
ENST000002695713788354737883800Frame-shift

check button Exon skipping position in the amino acid sequence.
ENSTExon skip start (DNA)Exon Skip end (DNA)Len(transcript seq)Exon skip start (mRNA)Exon Skip end (mRNA)Len(amino acid seq)Exon skip start (AA)Exon Skip end (AA)
ENST00000269571378655703786570545625997331255146191
ENST0000026957137876039378760874562205821051255633648
ENST0000026957137880164378802634562236824661255736769
ENST0000026957137880978378811644562246726521255769831
ENST0000026957137881301378814574562265328081255831883
ENST0000026957137881959378821064562288530311255908957

check button Potentially (partially) lost protein functional features of UniProt.
UniProtAccExon skip start (AA)Exon Skip end (AA)Function feature start (AA)Function feature end (AA)Functional feature typeFunctional feature desc.
P04626908957231255ChainID=PRO_0000016669;Note=Receptor tyrosine-protein kinase erbB-2
P04626736769231255ChainID=PRO_0000016669;Note=Receptor tyrosine-protein kinase erbB-2
P04626633648231255ChainID=PRO_0000016669;Note=Receptor tyrosine-protein kinase erbB-2
P04626146191231255ChainID=PRO_0000016669;Note=Receptor tyrosine-protein kinase erbB-2
P04626769831231255ChainID=PRO_0000016669;Note=Receptor tyrosine-protein kinase erbB-2
P04626831883231255ChainID=PRO_0000016669;Note=Receptor tyrosine-protein kinase erbB-2
P0462663364823652Topological domainNote=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
P0462614619123652Topological domainNote=Extracellular;Ontology_term=ECO:0000255;evidence=ECO:0000255
P046269089576761255Topological domainNote=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
P046267367696761255Topological domainNote=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
P046267698316761255Topological domainNote=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
P046268318836761255Topological domainNote=Cytoplasmic;Ontology_term=ECO:0000255;evidence=ECO:0000255
P04626908957720987DomainNote=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159
P04626736769720987DomainNote=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159
P04626769831720987DomainNote=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159
P04626831883720987DomainNote=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159
P04626831883845845Active siteNote=Proton acceptor;Ontology_term=ECO:0000255,ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159,ECO:0000255|PROSITE-ProRule:PRU10028
P04626736769753753Binding siteNote=ATP;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159
P04626146191182182Modified residueNote=Phosphothreonine;Ontology_term=ECO:0000244;evidence=ECO:0000244|PubMed:23186163;Dbxref=PMID:23186163
P04626146191187187GlycosylationNote=N-linked (GlcNAc...) asparagine;Ontology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000255;evidence=ECO:0000244|PDB:1N8Z,ECO:0000244|PDB:1S78,ECO:0000244|PDB:2A91,ECO:0000244|PDB:3N85,ECO:0000255
P04626146191162192Disulfide bondOntology_term=ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244,ECO:0000244;evidence=ECO:0000244|PDB:1N8Z,ECO:0000244|PDB:1S78,ECO:0000244|PDB:2A91,ECO:0000244|PDB:3BE1,ECO:0000244|PDB:3H3B,ECO:0000244|PDB:3MZW,ECO:0000244|PDB:3N85,ECO:0000244|PDB:3WLW,ECO:0000244|PDB:3WSQ,ECO:0000244|PDB:4HRL,ECO:0000244|PDB:4HRM
P04626633648626634Disulfide bondOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3N85
P04626633648630642Disulfide bondOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3N85
P046266336481686Alternative sequenceID=VSP_039250;Note=In isoform 3. Missing;Ontology_term=ECO:0000305;evidence=ECO:0000305
P046261461911686Alternative sequenceID=VSP_039250;Note=In isoform 3. Missing;Ontology_term=ECO:0000305;evidence=ECO:0000305
P046261461911610Alternative sequenceID=VSP_039249;Note=In isoform 2. Missing;Ontology_term=ECO:0000305;evidence=ECO:0000305
P04626633648633648Alternative sequenceID=VSP_055902;Note=In isoform 6. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:24722188;Dbxref=PMID:24722188
P04626769831771883Alternative sequenceID=VSP_055903;Note=In isoform 6. AYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHVRENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGK->TISNLFSNFAPRGPSACCEPTCWCHSGKGQDSLPREEWGRQRRFCLWGCRGEPRVLDTPGRSCPSAPPSSCLQPSLRQPLLLGPGPTRAGGSTQHLQRDTYGREPRVPGSGRASVNQKAKSAEALMCPQGAGKA;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:24722188;Dbxref=PMID:24722188
P04626831883771883Alternative sequenceID=VSP_055903;Note=In isoform 6. AYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHVRENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGK->TISNLFSNFAPRGPSACCEPTCWCHSGKGQDSLPREEWGRQRRFCLWGCRGEPRVLDTPGRSCPSAPPSSCLQPSLRQPLLLGPGPTRAGGSTQHLQRDTYGREPRVPGSGRASVNQKAKSAEALMCPQGAGKA;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:24722188;Dbxref=PMID:24722188
P046269089578841255Alternative sequenceID=VSP_055904;Note=In isoform 6. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:24722188;Dbxref=PMID:24722188
P04626736769755755Natural variantID=VAR_055432;Note=In LNCR%3B somatic mutation%3B unknown pathological significance. L->P;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15457249;Dbxref=dbSNP:rs121913469,PMID:15457249
P04626736769768768Natural variantID=VAR_042097;Note=L->S;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17344846;Dbxref=dbSNP:rs56366519,PMID:17344846
P04626769831774774Natural variantID=VAR_055433;Note=In LNCR%3B somatic mutation%3B unknown pathological significance. M->MAYVM;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15457249;Dbxref=PMID:15457249
P04626769831776776Natural variantID=VAR_042098;Note=In GASC%3B somatic mutation%3B unknown pathological significance. G->S;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:15457249,ECO:0000269|PubMed:17344846;Dbxref=dbSNP:rs28933369,PMID:15457249,PMID:17344846
P04626769831779779Natural variantID=VAR_055434;Note=In LNCR%3B somatic mutation%3B unknown pathological significance. S->SVGS;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15457249;Dbxref=PMID:15457249
P04626831883857857Natural variantID=VAR_042099;Note=In OC%3B somatic mutation%3B unknown pathological significance. N->S;Ontology_term=ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:15457249,ECO:0000269|PubMed:17344846;Dbxref=dbSNP:rs28933370,PMID:15457249,PMID:17344846
P04626908957914914Natural variantID=VAR_055435;Note=In GLM%3B somatic mutation%3B unknown pathological significance. E->K;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:15457249;Dbxref=dbSNP:rs28933368,PMID:15457249
P04626146191147150Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:2A91
P04626146191152156Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5MY6
P04626146191164166TurnOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3H3B
P04626146191169172HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:5MY6
P04626146191175177HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:1N8Z
P04626146191182184Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3H3B
P04626633648635637Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3N85
P04626736769730739Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3PP0
P04626736769748755Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3PP0
P04626736769761774HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3PP0
P04626769831761774HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3PP0
P04626769831785799Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3PP0
P04626769831806812HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3PP0
P04626769831814816TurnOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3PP0
P04626769831819838HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3PP0
P04626831883819838HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3PP0
P04626831883848850HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3PP0
P04626831883851855Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3PP0
P04626831883858861Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3PP0
P04626908957901916HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3PP0
P04626908957922925TurnOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3PP0
P04626908957928930HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3PP0
P04626908957931936HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3PP0
P04626908957949958HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3PP0


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Expression


check buttonGene expression level across TCGA pancancer
all structure

check buttonGene expression level across GTEx pantissue
all structure

check buttonExpression level of gene isoforms across TCGA pancancer
all structure

check buttonExpression level of gene isoforms across GTEx pantissue
all structure

check buttonCancer(tissue) type-specific expression level of Translation factor using z-score distriution
all structure

check buttonDifferential expression between tumor and matched normal (in the cancer types with more than 10 matched samples)
all structure
Cancer typeTranslation factorFCadj.pval
STADERBB22.083087823184470.00733334058895707
BLCAERBB21.709862938204280.014068603515625
BRCAERBB22.103790749033244.64802044953281e-07
THCAERBB21.027939272664445.71717197842929e-07
KICHERBB2-2.136180344105396.55651092529297e-06
LUADERBB21.650461206677288.94245335020896e-05
HNSCERBB2-3.649383757733939.1349647846073e-09


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Expression Regulation


check buttonTranslation factor expression regulation through miRNA binding
Cancer typeGenemiRNATargetScan binding score (Context++ score percentile)CoefficientPvalue


check buttonTranslation factor expression regulation through methylation in the promoter of Translation factor
all structure
Cancer typeGenemethyl group bmethyl group aDEG pvalavg methyl in bavg methyl in aavg exp in bavg exp in a
LIHCERBB2210.008561618708648840.244127128906250.1765761849710980.1581197152686250.0270168047737106
TGCTERBB2210.04529074587113720.2137049535603710.1560557364634610.6695190489075290.358306903330417

check buttonTranslation factor expression regulation through methylation in the gene body of Translation factor (positive regulation)
all structure
Cancer typeGenemethyl group bmethyl group aDEG pvalavg methyl in bavg methyl in aavg exp in bavg exp in a

check buttonTranslation factor expression regulation through copy number variation of Translation factor
all structure
Cancer typeGeneCoefficientPvalue
LGGERBB2-0.0602903440.049858555

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Associated Genes


check button Strongly correlated genes belong to cellular important gene groups with ERBB2 (coefficient>0.8, pval<0.05, node color based on FC between tumor and matched normal). Significantly associated important genes in the individual cancer types. * Cell metabolism gene: cell metabolism genes from REACTOME (black edge), IUPHAR: drug target genes from IUPHAR (blue edge), Kinase: human kinase genes (brown edge), CGC: cancer gene census genes (orange edge), TSG: tumor suppresor genes (purple edge), Epifactor: epigenetic factors (light blue edge), TF: transcription factors (green)
all structure
Cancer typeGene groupTranslation factorCorrelated geneCoefficientPvalue
TGCTCell metabolism geneERBB2AGRN0.8132743974.79E-38
TGCTCell metabolism geneERBB2GPC60.8205587413.02E-39
TGCTCell metabolism geneERBB2SLC44A30.8236487159.00E-40
TGCTCell metabolism geneERBB2SULT1E10.8310642074.46E-41
TGCTCell metabolism geneERBB2TEAD30.8633991741.30E-47
TGCTCGCERBB2BMP50.8105563451.30E-37
TGCTCGCERBB2PTPRK0.8328372082.13E-41
TGCTCGCERBB2TMPRSS20.8708388322.35E-49
TGCTEpifactorERBB2FOXP40.8189666765.58E-39
TGCTIUPHARERBB2SLC15A10.8028557922.04E-36
TGCTIUPHARERBB2CFTR0.8063335555.97E-37
TGCTIUPHARERBB2LGR50.8106550111.26E-37
TGCTIUPHARERBB2ABCC60.8161162971.65E-38
TGCTIUPHARERBB2ITGB60.8164205451.47E-38
TGCTIUPHARERBB2HSD11B20.8196623584.27E-39
TGCTIUPHARERBB2SLC44A30.8236487159.00E-40
TGCTIUPHARERBB2PTPRK0.8328372082.13E-41
TGCTIUPHARERBB2ADAMTS70.8334290141.66E-41
TGCTIUPHARERBB2HNF4G0.8522233043.53E-45
TGCTIUPHARERBB2CRABP20.8632122731.43E-47
TGCTIUPHARERBB2TMPRSS20.8708388322.35E-49
TGCTTFERBB2SOX110.8012566133.55E-36
TGCTTFERBB2FOXP40.8189666765.58E-39
TGCTTFERBB2HIF3A0.820997742.55E-39
TGCTTFERBB2HES10.8219100571.78E-39
TGCTTFERBB2SPDEF0.8221656771.61E-39
TGCTTFERBB2HNF4G0.8522233043.53E-45
TGCTTFERBB2TEAD30.8633991741.30E-47
TGCTTSGERBB2SOX110.8012566133.55E-36
TGCTTSGERBB2CFTR0.8063335555.97E-37
TGCTTSGERBB2VIL10.8116012588.88E-38
TGCTTSGERBB2BMP40.8264756362.91E-40
TGCTTSGERBB2SEMA3B0.8311278364.34E-41
TGCTTSGERBB2PTPRK0.8328372082.13E-41
TGCTTSGERBB2KRT190.8788007812.40E-51
THYMIUPHARERBB2ITGB80.8140428824.29E-30
UCSIUPHARERBB2ITGB80.8140428824.29E-30
UVMCell metabolism geneERBB2SMG60.8332451169.08E-22
UVMCell metabolism geneERBB2MED240.8483765933.01E-23
UVMCGCERBB2DCTN10.8326654281.03E-21
UVMCGCERBB2LASP10.8583675782.57E-24


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Protein structure


check button Protein 3D structure
Visit iCn3D.


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Protein-Protein Interaction


check button Protein-protein interaction networks
* Overlap between up-regulated DEGs (log2FC<-1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))
all structure

check buttonOverlap between down-regulated DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))
all structure
check button
* Edge colors based on TCGA cancer types.

check button* Overlap between DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network per cancer (center: Translation factor, node: DEGs, node color: log2FC, edges: weighted by -log2(adj.P))
all structure
Cancer typeTranslation factorInteracting protein coding geneFCadj.pval
LUSCERBB2EGFR1.327571383914170.000102202753672845
KICHERBB2CTNNB11.353870024263830.000139892101287842
KIRPERBB2CTNNB11.444136470305760.00019507110118866
KIRCERBB2GRB2-3.509622895290790.000210123708729258
LIHCERBB2GRB2-2.60706692664390.000329386776931513
LIHCERBB2HSP90AA1-1.871377396719020.0003817245773207
KIRPERBB2SHC1-1.285308664857450.000906126573681831
LUSCERBB2GRB2-1.601756684029190.00116257561090457
CHOLERBB2GRB72.576845637348820.00390625
LIHCERBB2EGFR-1.22305380940170.00496795806084514
KIRPERBB2ERBB2IP-1.611247020300310.00608485564589501
LUSCERBB2CTNNB1-1.536863158796340.00765883184752251
CHOLERBB2GRB2-1.288583683438540.01171875
HNSCERBB2EGF-3.204867008503260.0149245594448075
KICHERBB2ERBB2IP1.120334036701270.0173123478889465
CHOLERBB2NRG1-3.348522915342790.01953125
PRADERBB2CD441.045453824520330.0305494319135424
READERBB2GRB74.001217938022050.03125
ESCAERBB2HSP90AA1-2.954078329285750.0322265625
KIRPERBB2EGFR1.140563999273750.0394268441013992
HNSCERBB2GRB2-2.710378348559171.00141839993739e-05
BRCAERBB2HSP90AA12.19782205770151.13731762084626e-08
THCAERBB2SHC1-1.925729832571341.13787415943499e-05
KIRCERBB2GRB7-2.085572767596021.28432097821042e-12
KICHERBB2GRB7-1.358860983741961.78813934326172e-07
KIRCERBB2EGFR1.558363839377992.25998111659284e-12
KICHERBB2GRB21.694709010992392.5629997253418e-06
HNSCERBB2NRG11.155400139510392.86950125882868e-08
COADERBB2GRB71.936272284434472.98023223876954e-08
STADERBB2HSP90AA1-1.657051254302853.51201742887497e-06
LUADERBB2CD44-1.699657765290453.53668114331368e-08
KIRCERBB2CD44-1.145435007436683.61971983207531e-09
BRCAERBB2ERBB2IP1.500519332708294.79363542815941e-07
KIRCERBB2EGF-2.119444600922476.15531645908303e-13
KIRPERBB2EGF-2.438675538705749.31322574615479e-10


check button Protein-protein interactors with this translation factor (BIOGRID-3.4.160)
PPI interactors with ERBB2
SHC1, SH3BGRL, PTPN11, GRB2, MUC1, CTNNB1, ERBB2, CD82, EGF, PAK1, ERBB2IP, PICK1, PIK3R2, DLG4, ERBB4, Errfi1, NRG1, JUP, STAT3, SRC, JAK2, HSP90B1, CD44, GRB7, PLCG1, IL6ST, OSMR, PTK2B, HSP90AA1, ELF3, EGFR, ERBB3, HDAC6, LRIG1, STUB1, HSPA4, HSP82, IGF1R, CUL5, ESR1, PPP1R13B, H2AFY, PIK3R1, PIN1, PTK6, ACTB, POLR1B, KPNB1, XPO1, CLTC, AP2B1, EEA1, APBB1, SH2B2, IRS4, SH2D1B, SOCS1, NCK2, DAB1, GRAP2, APBB3, ABL1, FGR, CHN1, FER, PLCG2, RASA1, JAK1, IRS1, STAT1, MATK, TEC, TXK, ABL2, SYK, CRK, CRKL, BLK, BMX, VAV2, SH3BP2, SHC2, ITK, SLA, MAPK8IP2, RIN1, BCAR3, TENC1, TNS3, DOK6, SH2D5, SUPT6H, ANKS1B, CLNK, DOK4, BLNK, RIN2, SHC3, PIK3R3, ANKS1A, VAV1, DOK1, SH2D3A, SLA2, SH2D2A, CISH, VAV3, MAPK8IP1, SH2B3, TLN1, SRPK1, CBL, ERRFI1, FRS3, USP2, NXF1, DTWD2, TGFBR2, NAALADL2, LPAR6, VSIG4, PTGER3, CYP17A1, GLCE, IL13RA2, KLK5, LYPD3, NAT2, PRDM14, PSMC3IP, RHOBTB2, THRSP, ANXA6, BAI1, CLCN6, GMPR2, HDLBP, IARS, MTCH1, MUCL1, PHF23, POLD2, PSAP, STK24, TCEAL2, ATP6AP1, TTC9B, UTP18, ATP1A1, EEF1G, TNPO1, PC, SURF4, TFRC, VAPB, PTDSS1, HPSE, ZNF280C, CCDC88A, ZNF622, Tor1aip1, BTC, PTK2, TGFA, BCAR1, ESRRB, CDC37, EZR, RDX, ITGAV, L1CAM, ITGB1, CHEK2, TOP1, RRM2, CDK4, CDH2, CDH1, PTPN6, PTPRR, PTPRT, PTPRU, PTPRA, PTPRH, MPZL2, SSH1, CD79B, MAS1, HAVCR2, IL4R, PPM1A, PPM1F, ILKAP, DUSP14, DUSP18, DUSP19, STYX, GAB1, HNRNPL, OPCML, CPNE3, FBXO7, HSP90AB1, PLA2G2A, CXCL8, DOCK7, ADRB2, BECN1, SDC1, MUC4, CDC25A, PRKDC, CAMK2G, CDK12, GPX1, FGFR3, TK1, PIK3CB, BIRC5, PIK3CA, ADRBK1, GRIK5, CALM1, LRIG3, MCL1, KIAA1429, PDGFRB, EPHA1, EPHA2, EPHA3, EPHA4, EPHA5, EPHB1, EPHB2, EPHB3, EPHB6, FGFR1, FGFR2, FGFR4, INSR, INSRR, MST1R, MET, PDGFRA, PTK7, RET, ROR2, NTRK1, NTRK2, NTRK3, FLT3, FLT4, STYK1, ALK, MERTK, TYRO3, DDR1, TEK, CSK, HRAS, APEX1, PSMD3, CCND2, CDKN2B, LATS2, STK11, FZR1, GLIS2, MAP2K5, TTYH2, ABCB5, ARNT, CBLC, AKT1, AURKA, CDK6, CDKN2C, GRM1, HGF, KDELR2, MAP2K3, MYC, NF2, RAF1, RASSF1, TP53, ORF7b, AATK, ACP1, AIP, ALDOA, AP3B2, APLP1, ARF1, ARF5, ASRGL1, ATP6V0C, BNIP1, C10orf35, C14orf1, TMEM230, C21orf59, SMIM20, CBR1, CEND1, CLASP2, COL9A2, COL9A3, CRIP2, DST, FKBP3, FKBP8, FLNB, GABARAPL1, GABARAPL2, GLRX3, GPM6B, GAPDH, IRF2BP2, ITPKA, ITPR1, JMJD4, KCTD6, KLC1, LGALS8, LPCAT4, LRRC7, MDH1, MSN, MYO9A, NEFH, NINL, NUDT16L1, ODF2L, PDCD11, PGAM1, PIN4, POU6F1, PPA1, PSMA1, PTGES3L-AARSD1, RBM15B, RHBDD2, RPRML, RTN4, S100A11, SAFB2, SELK, SLC7A4, SMPD4, SNAP91, SPP1, STMN2, SYNM, TMEM134, TSEN15, TXN, TYMP, ZFAND1, ZMAT2, ZMYND8, ZNF532, RAB5C, TMA7, ILF3, AKAP12, HSPA9, HSPA1A, CCT3, PABPC1, YWHAZ, HSPD1, HSPA5, VAPA, STIP1, PSMC3, MEPCE, TRIP6, CACYBP, FKBP1A, STMN1, ALDOC, TVP23B, CSDE1, GSN, CFL1, PRDX5, CKB, PEBP1, nsp4, ORF3a, ORF7a, S, M, BAAT, C9orf156, CDK8, CYLC2, FBP1, FRAT2, HSD17B3, CCDC180, MAP2K1, SFRP4, SMAD1, TGFB1, ZNF189, TRIM66, FES, GRB10, GRB14, HCK, HSH2D, INPPL1, LCK, LCP2, LYN, NCK1, SH2B1, SH2D1A, SH2D3C, SHB, SHC4, SHD, SOCS3, SOCS5, SOCS6, STAP1, TNS1, YES1, ZAP70, HAX1, E5b, CUL4A, MKRN2, C11orf52, CAV1, FLOT1, GJA1, KRAS, OCLN, RAB35, STX6, AIM1, TIMP1, SLITRK3, SPCS1, CX3CL1, HCST, TMEM200A, ARL15, TICAM2, IGDCC4, ARL4D, PIGH, RELT, OPALIN, AQP3, ACVR1, AMHR2, EFNB1, SORL1, FBXW7, DEPTOR, BTRC,


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Mutations


check button Clinically associated variants from ClinVar.
GeneChrPositionRefSeqVarSeqRefSeeqVarTypePathogenicDiseaseVarInfo
ERBB2chr1737855834CAsingle_nucleotide_variantnot_providednot_specifiedSO:0001583|missense_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001627|intron_variant
ERBB2chr1737856534CTsingle_nucleotide_variantLikely_benignnot_specified|not_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001623|5_prime_UTR_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001623|5_prime_UTR_variant,SO:0001627|intron_variant
ERBB2chr1737863238GTsingle_nucleotide_variantLikely_benignnot_providedSO:0001627|intron_variantSO:0001627|intron_variant
ERBB2chr1737863250CTsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001623|5_prime_UTR_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001623|5_prime_UTR_variant,SO:0001627|intron_variant
ERBB2chr1737863262GTsingle_nucleotide_variantLikely_benignnot_specified|not_providedSO:0001582|initiatior_codon_variant,SO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001582|initiatior_codon_variant,SO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737863268GAsingle_nucleotide_variantBenignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737863280CAsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737863302AGsingle_nucleotide_variantnot_providednot_specifiedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737863309GAsingle_nucleotide_variantBenignnot_specified|not_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737864569CTsingle_nucleotide_variantLikely_benignnot_providedSO:0001627|intron_variantSO:0001627|intron_variant
ERBB2chr1737864584ACsingle_nucleotide_variantLikely_benignnot_specified|not_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737864606CTsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737864646CTsingle_nucleotide_variantUncertain_significancenot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737864655CTsingle_nucleotide_variantUncertain_significanceInborn_genetic_diseasesSO:0001587|nonsense,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001587|nonsense,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737864691GAsingle_nucleotide_variantUncertain_significancenot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737864693CTsingle_nucleotide_variantBenignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737864713CTsingle_nucleotide_variantUncertain_significancenot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737864729CGsingle_nucleotide_variantBenignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737864731CGsingle_nucleotide_variantnot_providednot_specifiedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737864776GAsingle_nucleotide_variantBenign/Likely_benignnot_specified|not_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737864781CTsingle_nucleotide_variantLikely_benignnot_specified|not_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737865601GAsingle_nucleotide_variantUncertain_significancenot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737865629GCsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737865659CTsingle_nucleotide_variantBenignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737865694GAsingle_nucleotide_variantUncertain_significanceGlioma_susceptibility_1SO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737866082GAsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737866084TCsingle_nucleotide_variantUncertain_significancenot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737866132GTsingle_nucleotide_variantUncertain_significancenot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737866343GAsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737866370CGsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737866383CTsingle_nucleotide_variantUncertain_significancenot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737866412GAsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737866429CTsingle_nucleotide_variantUncertain_significanceGlioma_susceptibility_1|not_specifiedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737866430GCsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737866583GTsingle_nucleotide_variantLikely_benignnot_providedSO:0001627|intron_variantSO:0001627|intron_variant
ERBB2chr1737866588CTsingle_nucleotide_variantUncertain_significanceGlioma_susceptibility_1SO:0001627|intron_variantSO:0001627|intron_variant
ERBB2chr1737866601CTsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737866641GTsingle_nucleotide_variantLikely_benignnot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737866649CAsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737866689GCsingle_nucleotide_variantUncertain_significancenot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737866707GAsingle_nucleotide_variantUncertain_significancenot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737866741GTsingle_nucleotide_variantBenignnot_providedSO:0001627|intron_variantSO:0001627|intron_variant
ERBB2chr1737868186TCsingle_nucleotide_variantUncertain_significancenot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant
ERBB2chr1737868205GAsingle_nucleotide_variantLikely_pathogenicLung_adenocarcinomaSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant
ERBB2chr1737868205GCsingle_nucleotide_variantLikely_pathogenicBreast_neoplasmSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant
ERBB2chr1737868208CAsingle_nucleotide_variantPathogenicNeoplasm|Squamous_cell_carcinoma_of_the_skin|Transitional_cell_carcinoma_of_the_bladder|Breast_neoplasm|Lung_adenocarcinoma|Neoplasm_of_uterine_cervix|Adenocarcinoma_of_stomach|Neoplasm_of_the_large_intestine|Ovarian_Serous_Cystadenocarcinoma|Squamous_celSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant
ERBB2chr1737868208CTsingle_nucleotide_variantLikely_pathogenicNeoplasm|Squamous_cell_carcinoma_of_the_skin|Transitional_cell_carcinoma_of_the_bladder|Breast_neoplasm|Lung_adenocarcinoma|Neoplasm_of_uterine_cervix|Adenocarcinoma_of_stomach|Neoplasm_of_the_large_intestine|Ovarian_Serous_Cystadenocarcinoma|Squamous_celSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant
ERBB2chr1737868319CTsingle_nucleotide_variantnot_providednot_specifiedSO:0001627|intron_variantSO:0001627|intron_variant
ERBB2chr1737868331CTsingle_nucleotide_variantnot_providednot_specifiedSO:0001627|intron_variantSO:0001627|intron_variant
ERBB2chr1737868348CTsingle_nucleotide_variantnot_providednot_specifiedSO:0001627|intron_variantSO:0001627|intron_variant
ERBB2chr1737868618AGsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant
ERBB2chr1737868691AGsingle_nucleotide_variantUncertain_significancenot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant
ERBB2chr1737871547CAsingle_nucleotide_variantLikely_benignnot_specified|not_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant
ERBB2chr1737871559CTsingle_nucleotide_variantnot_providednot_specifiedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant
ERBB2chr1737871707TGsingle_nucleotide_variantnot_providednot_specifiedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737871724GAsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737871745CTsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737871770CTsingle_nucleotide_variantUncertain_significancenot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737871996CAsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737871996CTsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737872005GTsingle_nucleotide_variantBenignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737872035GTsingle_nucleotide_variantBenignnot_specified|not_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737872045CTsingle_nucleotide_variantUncertain_significancenot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737872050AGsingle_nucleotide_variantBenignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737872064GAsingle_nucleotide_variantUncertain_significancenot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737872068TCsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737872095CTsingle_nucleotide_variantBenignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737872145CTsingle_nucleotide_variantUncertain_significanceGlioma_susceptibility_1|not_specified|not_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737872146GAsingle_nucleotide_variantBenignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737872168GAsingle_nucleotide_variantUncertain_significancenot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737872174CTsingle_nucleotide_variantUncertain_significancenot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737872558CTsingle_nucleotide_variantUncertain_significancenot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737872607CTsingle_nucleotide_variantUncertain_significancenot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737872609AGsingle_nucleotide_variantBenignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737872646CGCDeletionPathogenicMalignant_Colorectal_NeoplasmSO:0001589|frameshift_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001589|frameshift_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737872647GAsingle_nucleotide_variantUncertain_significancenot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737872696GAsingle_nucleotide_variantLikely_benignnot_providedSO:0001627|intron_variantSO:0001627|intron_variant
ERBB2chr1737872780GAsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737872834TCsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737872846CTsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737873566CAsingle_nucleotide_variantUncertain_significancenot_providedSO:0001627|intron_variantSO:0001627|intron_variant
ERBB2chr1737873568CGsingle_nucleotide_variantConflicting_interpretations_of_pathogenicityGlioma_susceptibility_1|not_providedSO:0001627|intron_variantSO:0001627|intron_variant
ERBB2chr1737873581CTsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737873607ATsingle_nucleotide_variantUncertain_significancenot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737873628CAsingle_nucleotide_variantUncertain_significancenot_specified|not_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737873698CTsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737873743AGsingle_nucleotide_variantLikely_benignnot_providedSO:0001624|3_prime_UTR_variant,SO:0001627|intron_variantSO:0001624|3_prime_UTR_variant,SO:0001627|intron_variant
ERBB2chr1737876073CTsingle_nucleotide_variantBenignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737879564GAsingle_nucleotide_variantLikely_benignnot_providedSO:0001627|intron_variantSO:0001627|intron_variant
ERBB2chr1737879585AGsingle_nucleotide_variantBenignERBB2_POLYMORPHISM|not_specified|not_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737879588AGsingle_nucleotide_variantBenignERBB2_POLYMORPHISM|not_specified|not_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737879615GTsingle_nucleotide_variantUncertain_significancenot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737879658GAsingle_nucleotide_variantLikely_pathogenicTransitional_cell_carcinoma_of_the_bladder|Breast_neoplasm|Adenocarcinoma_of_stomach|Neoplasm_of_the_large_intestine|Adenocarcinoma_of_prostate|Malignant_neoplasm_of_body_of_uterusSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737879673GAsingle_nucleotide_variantUncertain_significancenot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737879834CTsingle_nucleotide_variantPathogenicVISCERAL_NEUROPATHY,_FAMILIAL,_2,_AUTOSOMAL_RECESSIVESO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737879853AGsingle_nucleotide_variantBenignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737879877GAsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737880218GTTGAGGGAAAACACAGDeletionPathogenicBreast_neoplasmSO:0001619|non-coding_transcript_variant,SO:0001822|inframe_deletion,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001822|inframe_deletion,SO:0001627|intron_variant
ERBB2chr1737880219TAsingle_nucleotide_variantLikely_pathogenicTransitional_cell_carcinoma_of_the_bladder|Breast_neoplasm|Malignant_melanoma_of_skin|Adenocarcinoma_of_stomach|Neoplasm_of_the_large_intestine|Papillary_renal_cell_carcinoma,_sporadic|Malignant_neoplasm_of_body_of_uterusSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737880219TTCCIndelPathogenic/Likely_pathogenicTransitional_cell_carcinoma_of_the_bladder|Breast_neoplasm|Malignant_melanoma_of_skin|Lung_adenocarcinoma|Adenocarcinoma_of_stomach|Neoplasm_of_the_large_intestine|Papillary_renal_cell_carcinoma,_sporadic|Malignant_neoplasm_of_body_of_uterusSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737880220TCsingle_nucleotide_variantLikely_pathogenicTransitional_cell_carcinoma_of_the_bladder|Breast_neoplasm|Malignant_melanoma_of_skin|Adenocarcinoma_of_stomach|Neoplasm_of_the_large_intestine|Papillary_renal_cell_carcinoma,_sporadic|Malignant_neoplasm_of_body_of_uterusSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737880220TGsingle_nucleotide_variantLikely_pathogenicTransitional_cell_carcinoma_of_the_bladder|Breast_neoplasm|Malignant_melanoma_of_skin|Adenocarcinoma_of_stomach|Neoplasm_of_the_large_intestine|Papillary_renal_cell_carcinoma,_sporadic|Malignant_neoplasm_of_body_of_uterusSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737880261GAsingle_nucleotide_variantLikely_pathogenicTransitional_cell_carcinoma_of_the_bladder|Breast_neoplasm|Carcinoma_of_esophagus|Neoplasm_of_uterine_cervix|Adenocarcinoma_of_stomachSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737880261GCsingle_nucleotide_variantPathogenic/Likely_pathogenicTransitional_cell_carcinoma_of_the_bladder|Breast_neoplasm|Carcinoma_of_esophagus|Neoplasm_of_uterine_cervix|Adenocarcinoma_of_stomachSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737880261GTsingle_nucleotide_variantPathogenic/Likely_pathogenicTransitional_cell_carcinoma_of_the_bladder|Breast_neoplasm|Carcinoma_of_esophagus|Neoplasm_of_uterine_cervix|Adenocarcinoma_of_stomachSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737880270CTsingle_nucleotide_variantLikely_benignnot_providedSO:0001627|intron_variantSO:0001627|intron_variant
ERBB2chr1737880981AAGCATACGTGATGDuplicationLikely_pathogenicLung_adenocarcinoma|Non-small_cell_lung_carcinomaSO:0001619|non-coding_transcript_variant,SO:0001821|inframe_insertion,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001821|inframe_insertion,SO:0001627|intron_variant
ERBB2chr1737880984AATACGTGATGGCTDuplicationLikely_pathogenicNon-small_cell_lung_carcinomaSO:0001619|non-coding_transcript_variant,SO:0001821|inframe_insertion,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001821|inframe_insertion,SO:0001627|intron_variant
ERBB2chr1737880986AACGTGATGGCCTCInsertionLikely_pathogenicNon-small_cell_lung_carcinomaSO:0001619|non-coding_transcript_variant,SO:0001821|inframe_insertion,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001821|inframe_insertion,SO:0001627|intron_variant
ERBB2chr1737880986AACGTGATGGCTTCInsertionLikely_pathogenicNon-small_cell_lung_carcinomaSO:0001619|non-coding_transcript_variant,SO:0001821|inframe_insertion,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001821|inframe_insertion,SO:0001627|intron_variant
ERBB2chr1737880988GAsingle_nucleotide_variantUncertain_significancenot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737880990GAGDeletionLikely_pathogenicNon-small_cell_lung_carcinomaSO:0001589|frameshift_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001589|frameshift_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737880997GAsingle_nucleotide_variantPathogenic/Likely_pathogenicNeoplasm|Gastric_cancer|Adenocarcinoma_of_stomachSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737880997GGTCTInsertionUncertain_significancenot_specifiedSO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant,SO:0001820|inframe_indelSO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant,SO:0001820|inframe_indel
ERBB2chr1737880997GGTGTInsertionLikely_pathogenicBreast_neoplasm|Non-small_cell_lung_carcinomaSO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant,SO:0001820|inframe_indelSO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant,SO:0001820|inframe_indel
ERBB2chr1737880997GGTTTInsertionLikely_pathogenicNon-small_cell_lung_carcinomaSO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant,SO:0001820|inframe_indelSO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant,SO:0001820|inframe_indel
ERBB2chr1737880997GTTATIndelLikely_pathogenicNon-small_cell_lung_carcinomaSO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant,SO:0001820|inframe_indelSO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant,SO:0001820|inframe_indel
ERBB2chr1737880998GGTGTGGGCTCDuplicationPathogenicLung_adenocarcinomaSO:0001619|non-coding_transcript_variant,SO:0001821|inframe_insertion,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001821|inframe_insertion,SO:0001627|intron_variant
ERBB2chr1737880998GTsingle_nucleotide_variantnot_providednot_specifiedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737881000GAsingle_nucleotide_variantLikely_pathogenicBreast_neoplasm|Adenocarcinoma_of_stomach|Neoplasm_of_the_large_intestineSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737881000GCsingle_nucleotide_variantLikely_pathogenicBreast_neoplasmSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737881000GTsingle_nucleotide_variantUncertain_significanceBreast_neoplasm|Adenocarcinoma_of_stomach|Neoplasm_of_the_large_intestine|not_specifiedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737881001TTGGGCTCCCCDuplicationPathogenicNon-small_cell_lung_carcinomaSO:0001619|non-coding_transcript_variant,SO:0001821|inframe_insertion,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001821|inframe_insertion,SO:0001627|intron_variant
ERBB2chr1737881002GGGGCTCCCCADuplicationLikely_pathogenicNon-small_cell_lung_carcinomaSO:0001619|non-coding_transcript_variant,SO:0001821|inframe_insertion,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001821|inframe_insertion,SO:0001627|intron_variant
ERBB2chr1737881003GGGGCTCCCCAInsertionPathogenicBreast_neoplasmSO:0001619|non-coding_transcript_variant,SO:0001821|inframe_insertion,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001821|inframe_insertion,SO:0001627|intron_variant
ERBB2chr1737881025TCsingle_nucleotide_variantLikely_pathogenicBreast_neoplasmSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737881050GAsingle_nucleotide_variantBenignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737881071TCsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737881102CTsingle_nucleotide_variantUncertain_significancenot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737881111CTsingle_nucleotide_variantnot_providednot_specifiedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737881114GAsingle_nucleotide_variantLikely_benignnot_specifiedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737881143CTsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737881169GAsingle_nucleotide_variantUncertain_significancenot_providedSO:0001627|intron_variantSO:0001627|intron_variant
ERBB2chr1737881299CTsingle_nucleotide_variantnot_providedFamilial_cancer_of_breastSO:0001627|intron_variantSO:0001627|intron_variant
ERBB2chr1737881314CTsingle_nucleotide_variantnot_providedEndometrial_carcinomaSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737881328GAsingle_nucleotide_variantnot_providedFamilial_cancer_of_breastSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737881332GAsingle_nucleotide_variantPathogenic/Likely_pathogenicPancreatic_adenocarcinoma|Breast_neoplasm|Adenocarcinoma_of_stomach|Neoplasm_of_the_large_intestine|Carcinoma_of_gallbladder|Uterine_Carcinosarcoma|Malignant_neoplasm_of_body_of_uterusSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737881343CTsingle_nucleotide_variantnot_providedFamilial_cancer_of_breastSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737881344TCsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737881349CTsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737881376CTsingle_nucleotide_variantnot_providedFamilial_cancer_of_breastSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737881378AGsingle_nucleotide_variantPathogenic/Likely_pathogenicNeoplasm_of_ovary|Ovarian_AdenocarcinomaSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737881413CTsingle_nucleotide_variantnot_providedNeoplasm_of_ovarySO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737881414TGsingle_nucleotide_variantPathogenicLung_adenocarcinomaSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737881575CGsingle_nucleotide_variantBenignnot_providedSO:0001627|intron_variantSO:0001627|intron_variant
ERBB2chr1737881616CTsingle_nucleotide_variantPathogenicBreast_neoplasmSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737881618CTsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737881636GCsingle_nucleotide_variantUncertain_significanceMalignant_tumor_of_prostateSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737881654TCsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737881974GAsingle_nucleotide_variantPathogenicGlioma_susceptibility_1SO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737882003CTsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737882020GAsingle_nucleotide_variantLikely_benignnot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737882024GTsingle_nucleotide_variantBenignnot_specified|not_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737882060CTsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737882110CTsingle_nucleotide_variantUncertain_significancenot_providedSO:0001627|intron_variantSO:0001627|intron_variant
ERBB2chr1737882856TCsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737883113CTsingle_nucleotide_variantUncertain_significancenot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737883133TCsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737883141GAsingle_nucleotide_variantUncertain_significanceGlioma_susceptibility_1|not_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737883167CTsingle_nucleotide_variantBenignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737883175CTsingle_nucleotide_variantBenignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737883178GAsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737883183GCsingle_nucleotide_variantUncertain_significancenot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737883205CTsingle_nucleotide_variantBenignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737883212GAsingle_nucleotide_variantLikely_benignnot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737883243GAsingle_nucleotide_variantnot_providedFamilial_cancer_of_breastSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737883246CTsingle_nucleotide_variantUncertain_significanceGlioma_susceptibility_1SO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737883253CGsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737883257GCsingle_nucleotide_variantUncertain_significancenot_providedSO:0001575|splice_donor_variant,SO:0001627|intron_variantSO:0001575|splice_donor_variant,SO:0001627|intron_variant
ERBB2chr1737883540GAsingle_nucleotide_variantLikely_benignnot_providedSO:0001627|intron_variantSO:0001627|intron_variant
ERBB2chr1737883570TCsingle_nucleotide_variantUncertain_significancenot_specified|not_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737883638GTsingle_nucleotide_variantUncertain_significancenot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737883656CTsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737883696CTsingle_nucleotide_variantUncertain_significancenot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737883720GAsingle_nucleotide_variantUncertain_significancenot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737883748GAsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737883763TAsingle_nucleotide_variantUncertain_significancenot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737883784CTsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001627|intron_variant
ERBB2chr1737883791CTsingle_nucleotide_variantBenignnot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001627|intron_variant
ERBB2chr1737883956CAsingle_nucleotide_variantnot_providednot_specifiedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001624|3_prime_UTR_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001624|3_prime_UTR_variant
ERBB2chr1737883957CTsingle_nucleotide_variantnot_providednot_specifiedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001624|3_prime_UTR_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001624|3_prime_UTR_variant
ERBB2chr1737883959GCsingle_nucleotide_variantUncertain_significancenot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001624|3_prime_UTR_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001624|3_prime_UTR_variant
ERBB2chr1737883965CTsingle_nucleotide_variantUncertain_significancenot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001624|3_prime_UTR_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001624|3_prime_UTR_variant
ERBB2chr1737883966GAsingle_nucleotide_variantUncertain_significancenot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001624|3_prime_UTR_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001624|3_prime_UTR_variant
ERBB2chr1737883970CTsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001624|3_prime_UTR_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001624|3_prime_UTR_variant
ERBB2chr1737883982GAsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001624|3_prime_UTR_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001624|3_prime_UTR_variant
ERBB2chr1737884011GAsingle_nucleotide_variantBenignnot_specified|not_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001624|3_prime_UTR_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001624|3_prime_UTR_variant
ERBB2chr1737884013CCGInsertionPathogenicMalignant_Colorectal_NeoplasmSO:0001589|frameshift_variant,SO:0001619|non-coding_transcript_variant,SO:0001624|3_prime_UTR_variantSO:0001589|frameshift_variant,SO:0001619|non-coding_transcript_variant,SO:0001624|3_prime_UTR_variant
ERBB2chr1737884013CTsingle_nucleotide_variantUncertain_significancenot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001624|3_prime_UTR_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001624|3_prime_UTR_variant
ERBB2chr1737884037CGsingle_nucleotide_variantBenignnot_specified|not_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001624|3_prime_UTR_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001624|3_prime_UTR_variant
ERBB2chr1737884046CGsingle_nucleotide_variantUncertain_significancenot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001624|3_prime_UTR_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001624|3_prime_UTR_variant
ERBB2chr1737884050CGsingle_nucleotide_variantUncertain_significancenot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001624|3_prime_UTR_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001624|3_prime_UTR_variant
ERBB2chr1737884069CTsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001624|3_prime_UTR_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001624|3_prime_UTR_variant
ERBB2chr1737884078CTsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001624|3_prime_UTR_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001624|3_prime_UTR_variant
ERBB2chr1737884120GAsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001624|3_prime_UTR_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001624|3_prime_UTR_variant
ERBB2chr1737884149CTsingle_nucleotide_variantnot_providednot_specifiedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001624|3_prime_UTR_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001624|3_prime_UTR_variant
ERBB2chr1737884159TCsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001624|3_prime_UTR_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001624|3_prime_UTR_variant
ERBB2chr1737884176CAsingle_nucleotide_variantBenignnot_specified|not_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001624|3_prime_UTR_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001624|3_prime_UTR_variant
ERBB2chr1737884180CTsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001624|3_prime_UTR_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001624|3_prime_UTR_variant
ERBB2chr1737884191AGsingle_nucleotide_variantUncertain_significancenot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001624|3_prime_UTR_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001624|3_prime_UTR_variant
ERBB2chr1737884218GTsingle_nucleotide_variantnot_providednot_specifiedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001624|3_prime_UTR_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001624|3_prime_UTR_variant
ERBB2chr1737884234CTsingle_nucleotide_variantBenignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001624|3_prime_UTR_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001624|3_prime_UTR_variant
ERBB2chr1737884270GAsingle_nucleotide_variantLikely_benignnot_providedSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001624|3_prime_UTR_variantSO:0001619|non-coding_transcript_variant,SO:0001819|synonymous_variant,SO:0001624|3_prime_UTR_variant
ERBB2chr1737884292GTsingle_nucleotide_variantUncertain_significancenot_providedSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001624|3_prime_UTR_variantSO:0001583|missense_variant,SO:0001619|non-coding_transcript_variant,SO:0001624|3_prime_UTR_variant


check button nsSNVs with sample frequency (size of circle) from TCGA 33 cancers.
all structure


check button SNVs and Indels
GeneCancer typeChromosomeStartEndRefSeeqMutSeqMutation typeAAchange# samples
ERBB2BLCAchr173786820837868208CTMissense_Mutation39
ERBB2BLCAchr173786820837868208CTMissense_Mutationp.S280F31
ERBB2BLCAchr173786820837868208CTMissense_Mutationp.S310F18
ERBB2BLCAchr173788022037880220TCMissense_Mutationp.L755S16
ERBB2BRCAchr173788133237881332GAMissense_Mutationp.V842I14
ERBB2BRCAchr173787965837879658GAMissense_Mutationp.R678Q10
ERBB2BLCAchr173788100037881000GTMissense_Mutation8
ERBB2LUADchr173788098137880982-GCATACGTGATGIn_Frame_Insp.740_740D>EHT*C8
ERBB2BLCAchr173788133237881332GAMissense_Mutationp.V812I7
ERBB2BRCAchr173788100037881000GCMissense_Mutationp.V777L7
ERBB2BLCAchr173788133237881332GAMissense_Mutation7
ERBB2LUADchr173786463937864639GASilentp.Q67Q6
ERBB2BRCAchr173788026137880261GTMissense_Mutationp.D769Y6
ERBB2CHOLchr173788021937880219TCSilentp.L755L5
ERBB2BLCAchr173787965837879658GAMissense_Mutationp.R648Q5
ERBB2BLCAchr173788100037881000GTMissense_Mutationp.V747L5
ERBB2BRCAchr173788026137880261GCMissense_Mutationp.D769H4
ERBB2ESCAchr173788100037881000GAMissense_Mutationp.V777M4
ERBB2BLCAchr173786820837868208CAMissense_Mutationp.S280Y4
ERBB2LIHCchr173788288837882888C-Frame_Shift_Delp.D952fs4
ERBB2BLCAchr173788022037880220TCMissense_Mutation4
ERBB2BLCAchr173788026137880261GAMissense_Mutation4
ERBB2UCECchr173787961337879613TCMissense_Mutationp.L663P3
ERBB2HNSCchr173788198237881982GAMissense_Mutationp.M886I3
ERBB2UCECchr173788362637883626GTMissense_Mutationp.G1080W3
ERBB2BLCAchr173788022037880220TCMissense_Mutationp.L725S3
ERBB2BLCAchr173788139237881392AGMissense_Mutation3
ERBB2SKCMchr173787160837871608CTSilentp.I376I3
ERBB2UCECchr173786465037864650TGMissense_Mutationp.I101S3
ERBB2BLCAchr173787958337879583CGMissense_Mutation3
ERBB2BLCAchr173786644437866444CTMissense_Mutation3
ERBB2STADchr173788321237883212GAMissense_Mutationp.A1039T3
ERBB2BLCAchr173787958837879588AGMissense_Mutation3
ERBB2KIRPchr173787608037876080ACSilentp.R647R3
ERBB2BRCAchr173786820537868205GCMissense_Mutationp.G309A3
ERBB2CHOLchr173788021937880219TCSilent3
ERBB2BLCAchr173786465637864656GAMissense_Mutationp.R73Q2
ERBB2HNSCchr173786567637865676CTMissense_Mutationp.T152I2
ERBB2ESCAchr173788102137881021CTMissense_Mutation2
ERBB2SKCMchr173788308237883082CTSilentp.G965G2
ERBB2PRADchr173788101437881014TCSilentp.Y751Y2
ERBB2ESCAchr173787961037879610TAMissense_Mutationp.L662Q2
ERBB2ESCAchr173788132337881323GAMissense_Mutation2
ERBB2BLCAchr173788139237881392AGMissense_Mutationp.T862A2
ERBB2THYMchr173788142737881427CTSilent2
ERBB2LUADchr173788098137880982-GCATACGTGATGIn_Frame_Insp.774_775insAYVM2
ERBB2CHOLchr173788021937880219TCSilentp.L725L2
ERBB2PAADchr173786460737864607GAMissense_Mutation2
ERBB2SKCMchr173788204537882045GASilentp.K907K2
ERBB2SKCMchr173788200937882009GASilentp.G895G2
ERBB2BLCAchr173787965837879658GAMissense_Mutation2
ERBB2ESCAchr173788132337881323GAMissense_Mutationp.V839M2
ERBB2BLCAchr173786635937866359GTMissense_Mutationp.G222C2
ERBB2HNSCchr173788198237881982GAMissense_Mutationp.M916I2
ERBB2PAADchr173786829437868294GAMissense_Mutation2
ERBB2SKCMchr173786476337864763GAMissense_Mutationp.E109K2
ERBB2SKCMchr173787984837879848CTSilentp.L685L2
ERBB2CESCchr173786640737866407GAMissense_Mutation2
ERBB2THYMchr173788107537881075CTMissense_Mutation2
ERBB2BLCAchr173788025737880257CGMissense_Mutation2
ERBB2LGGchr173786609837866098CTMissense_Mutationp.R173C2
ERBB2LUADchr173788421737884218-GFrame_Shift_Insp.R1230fs2
ERBB2ESCAchr173786557937865579AGMissense_Mutationp.K150E2
ERBB2UCECchr173786608237866082GASilentp.P1972
ERBB2BRCAchr173787208937872089TGMissense_Mutationp.H470Q2
ERBB2HNSCchr173788422937884229CTMissense_Mutationp.P1204S2
ERBB2BLCAchr173788139237881392AGMissense_Mutationp.T832A2
ERBB2SKCMchr173787208337872083CTSilentp.I438I2
ERBB2CESCchr173788425537884255GASilent2
ERBB2BLCAchr173786667137866671GCMissense_Mutation2
ERBB2UCECchr173787982037879820GASilentp.A7052
ERBB2BRCAchr173788025737880257CGMissense_Mutationp.I767M2
ERBB2SKCMchr173786643437866434CTMissense_Mutationp.P217S2
ERBB2PAADchr173788396637883966GAMissense_Mutation2
ERBB2SKCMchr173786460637864606CTSilentp.I56I2
ERBB2THYMchr173788107537881075CTMissense_Mutationp.P802S2
ERBB2ESCAchr173788102137881021CTMissense_Mutationp.R784C2
ERBB2STADchr173788099837880998GTMissense_Mutationp.G776V2
ERBB2UCECchr173788020737880207GAMissense_Mutationp.A751T2
ERBB2BLCAchr173786465637864656GAMissense_Mutation2
ERBB2SKCMchr173786476037864760CTMissense_Mutationp.R108W2
ERBB2TGCTchr173787962637879626GCMissense_Mutation2
ERBB2PAADchr173786460737864607GAMissense_Mutationp.A87T2
ERBB2SKCMchr173788409237884092GAMissense_Mutationp.G1158E2
ERBB2THYMchr173786560037865600CTMissense_Mutationp.R157W2
ERBB2LGGchr173786609837866098CTMissense_Mutation2
ERBB2ESCAchr173786641737866417CTMissense_Mutation2
ERBB2STADchr173786328537863285CTMissense_Mutationp.P39L2
ERBB2UCECchr173788140037881400CTSilentp.F8642
ERBB2BLCAchr173786666237866662GTMissense_Mutationp.D247Y2
ERBB2BRCAchr173788356137883561ACMissense_Mutationp.D1058A2
ERBB2PAADchr173788202437882024GTMissense_Mutationp.E930D2
ERBB2SKCMchr173786671137866711CTMissense_Mutationp.A263V2
ERBB2BLCAchr173788025737880257CGMissense_Mutationp.I737M2
ERBB2CESCchr173787960337879603GCMissense_Mutation2
ERBB2ESCAchr173787961037879610TAMissense_Mutation2
ERBB2STADchr173786463637864636GASilentp.L96L2
ERBB2UCECchr173788162037881620GAMissense_Mutationp.R897Q2
ERBB2PAADchr173788396637883966GAMissense_Mutationp.R1146Q2
ERBB2SKCMchr173788131037881310CTSilentp.S804S2
ERBB2CESCchr173788142537881425GAMissense_Mutation2
ERBB2DLBCchr173787958837879588AGMissense_Mutationp.I655V2
ERBB2STADchr173787960137879601TAMissense_Mutation2
ERBB2KIRPchr173788359737883597CTMissense_Mutationp.A1070V2
ERBB2HNSCchr173788311337883113CTMissense_Mutationp.R976C2
ERBB2ESCAchr173786557937865579AGMissense_Mutation2
ERBB2STADchr173787367037873670CAMissense_Mutationp.P612H2
ERBB2UCECchr173788426137884261GTMissense_Mutationp.E1244D2
ERBB2BLCAchr173788394937883949GASilentp.V1110V2
ERBB2LIHCchr173788373337883733C-Frame_Shift_Delp.D1085fs2
ERBB2SKCMchr173788307437883074GAMissense_Mutationp.D963N2
ERBB2CESCchr173787159337871593GCMissense_Mutation2
ERBB2ESCAchr173786641737866417CTMissense_Mutationp.A241V2
ERBB2STADchr173788321237883212GAMissense_Mutation2
ERBB2BLCAchr173786635237866352CASilent1
ERBB2LIHCchr173788418837884188TCMissense_Mutation1
ERBB2OVchr173512173435121734CTMissense_Mutation1
ERBB2SARCchr173787282337872823CTNonsense_Mutation1
ERBB2BLCAchr173787982037879820GASilentp.A705A1
ERBB2CHOLchr173788307737883077TGMissense_Mutation1
ERBB2STADchr173788321237883212GAMissense_Mutationp.A1009T1
ERBB2HNSCchr173787267437872674GAMissense_Mutation1
ERBB2BLCAchr173788026137880261GCMissense_Mutationp.D739H1
ERBB2COADchr173787959537879595CTMissense_Mutationp.A627V1
ERBB2SKCMchr173788367937883679GASilentp.G1067G1
ERBB2ESCAchr173788098837880989-TGAIn_Frame_Insp.742_743ins*1
ERBB2TGCTchr173787962637879626GCMissense_Mutationp.L637F1
ERBB2BLCAchr173787362037873620CAMissense_Mutation1
ERBB2BLCAchr173788099737880997GAMissense_Mutationp.G746S1
ERBB2KICHchr173788111737881117CTMissense_Mutation1
ERBB2LIHCchr173786859437868594G-Frame_Shift_Delp.M317fs1
ERBB2PAADchr173786460737864607GAMissense_Mutationp.A57T1
ERBB2LUADchr173786560537865605CTSilentp.N158N1
ERBB2BLCAchr173787173137871731CTSilentp.L389L1
ERBB2CESCchr173788362337883623GGMissense_Mutation1
ERBB2STADchr173787203637872036CAMissense_Mutation1
ERBB2HNSCchr173786821537868215CGSilent1
ERBB2BLCAchr173788404837884048CGSilent1
ERBB2BLCAchr173787283937872839CTMissense_Mutationp.S543L1
ERBB2KIRPchr173788359737883597CTMissense_Mutationp.A1040V1
ERBB2BLCAchr173787171437871714CTMissense_Mutation1
ERBB2HNSCchr173787962937879629GTSilentp.G638G1
ERBB2LIHCchr173787283937872839CANonsense_Mutationp.S573X1
ERBB2OVchr173513490135134901CGMissense_Mutationp.P856R1
ERBB2SARCchr173786609337866093GTMissense_Mutation1
ERBB2BLCAchr173786465637864656GAMissense_Mutationp.R103Q1
ERBB2ESCAchr173786564437865644CTSilent1
ERBB2STADchr173787960137879601TAMissense_Mutationp.V629D1
ERBB2PAADchr173788202437882024GTMissense_Mutationp.E900D1
ERBB2SKCMchr173786559737865597CTNonsense_Mutationp.Q126X1
ERBB2BLCAchr173786565637865656GASilentp.K145K1
ERBB2COADchr173787968837879688GAMissense_Mutationp.R658Q1
ERBB2SKCMchr173788367837883678GAMissense_Mutationp.G1067E1
ERBB2GBMchr173788412437884124CAMissense_Mutationp.P1199T1
ERBB2THCAchr173788204437882044AGMissense_Mutation1
ERBB2BLCAchr173788197937881979GCSilent1
ERBB2KIRCchr173786635037866350GAMissense_Mutationp.V219I1
ERBB2LIHCchr173788165437881654T-Splice_Sitep.Y878_splice1
ERBB2KIRPchr173788316437883164T-Frame_Shift_Delp.Y1023fs1
ERBB2LUADchr173786560537865605CTSilentp.N128N1
ERBB2LUADchr173787159337871593GASilentp.E401E1
ERBB2PRADchr173787256137872561G-Frame_Shift_Delp.E477fs1
ERBB2BLCAchr173788425937884259GCMissense_Mutationp.E1244Q1
ERBB2CESCchr173788311737883117CCMissense_Mutation1
ERBB2ESCAchr173788098837880989-TGAIn_Frame_Insp.775in_frame_insM1
ERBB2STADchr173787203637872036CAMissense_Mutationp.L453M1
ERBB2HNSCchr173788202237882022GAMissense_Mutation1
ERBB2BLCAchr173788418037884180CTSilent1
ERBB2STADchr173787958337879583CTMissense_Mutationp.S623F1
ERBB2HNSCchr173788202237882022GAMissense_Mutationp.E900K1
ERBB2BLCAchr173786635237866352CASilentp.V189V1
ERBB2HNSCchr173786821537868215CGSilentp.T282T1
ERBB2LIHCchr173787605237876052GASilentp.L637L1
ERBB2OVchr173512173435121734CTMissense_Mutationp.S310F1
ERBB2SARCchr173786478337864783CTSilentp.L1451
ERBB2CHOLchr173788307737883077TGMissense_Mutationp.L994V1
ERBB2PAADchr173788396637883966GAMissense_Mutationp.R1116Q1
ERBB2BLCAchr173788415137884151CTMissense_Mutationp.H1178Y1
ERBB2COADchr173788308837883088CASilentp.A967A1
ERBB2SKCMchr173786637037866370CTSilentp.A195A1
ERBB2GBMchr173786666737866667GASilentp.T278T1
ERBB2BLCAchr173788313437883134GCMissense_Mutation1
ERBB2KIRCchr173787154937871550-CFrame_Shift_Insp.S387fs1
ERBB2LIHCchr173788377437883774C-Frame_Shift_Delp.A1099fs1
ERBB2KIRPchr173787608037876080ACSilent1
ERBB2LUADchr173787159337871593GASilentp.E371E1
ERBB2READchr173787979437879794GTMissense_Mutationp.V667L1
ERBB2BLCAchr173787283937872839CTMissense_Mutationp.S573L1
ERBB2CESCchr173786640737866407GAMissense_Mutationp.E238K1
ERBB2STADchr173787958337879583CTMissense_Mutationp.S653F1
ERBB2HNSCchr173788356137883561ACMissense_Mutation1
ERBB2BLCAchr173787990337879903CTMissense_Mutation1
ERBB2ESCAchr173788098837880989-TGAIn_Frame_Insp.V773delinsVM1
ERBB2STADchr173787203637872036CAMissense_Mutationp.L423M1
ERBB2HNSCchr173786634637866346CTSilentp.R187R1
ERBB2BLCAchr173786607837866078CTMissense_Mutationp.S166F1
ERBB2HNSCchr173788018037880180GCMissense_Mutationp.D742H1
ERBB2LIHCchr173788288637882886GTMissense_Mutationp.D982Y1
ERBB2BLCAchr173786820037868200CTSilentp.D307D1
ERBB2PAADchr173786327737863277TASilentp.P36P1
ERBB2BLCAchr173786868237868682CTSilentp.L347L1
ERBB2BRCAchr173787958137879581GTSilentp.T6521
ERBB2COADchr173788376937883769CTSilentp.Y1097Y1
ERBB2SKCMchr173788409137884091GAMissense_Mutationp.G1158R1
ERBB2GBMchr173788409337884093GTSilent1
ERBB2THYMchr173786326237863262GTTranslation_Start_Site1
ERBB2BLCAchr173786460337864603CGSilent1
ERBB2KIRCchr173787608737876087GCMissense_Mutationp.S649T1
ERBB2LIHCchr173786334037863340G-Frame_Shift_Delp.Q27fs1
ERBB2KIRPchr173788359737883597CTMissense_Mutation1
ERBB2LUADchr173786637337866373CTSilentp.R196R1
ERBB2LUADchr173788099737880998-TCTIn_Frame_Insp.776_776G>VC1
ERBB2READchr173788099837880998GTMissense_Mutationp.G746V1
ERBB2CESCchr173786667137866671GCMissense_Mutationp.E280Q1
ERBB2STADchr173786820837868208CAMissense_Mutationp.S310Y1
ERBB2HNSCchr173787962937879629GTSilent1
ERBB2UCECchr173788421837884218G-Frame_Shift_Delp.R1230fs1
ERBB2BLCAchr173787982037879820GASilent1
ERBB2BLCAchr173788418037884180CTSilentp.F1187F1
ERBB2CHOLchr173788307737883077TGMissense_Mutationp.L964V1
ERBB2ESCAchr173786641737866417CTMissense_Mutationp.A211V1
ERBB2STADchr173785654037856540C-Frame_Shift_Delp.P18fs1
ERBB2HNSCchr173788398237883982GASilentp.S1121S1
ERBB2BLCAchr173786635937866359GTMissense_Mutation1
ERBB2BLCAchr173787171437871714CTMissense_Mutationp.S383L1
ERBB2LIHCchr173786828237868282AGMissense_Mutationp.S335G1
ERBB2PAADchr173786829437868294GAMissense_Mutationp.A339T1
ERBB2BLCAchr173787362037873620CAMissense_Mutationp.F565L1
ERBB2COADchr173788420837884208CTMissense_Mutationp.P1197S1
ERBB2SKCMchr173787361537873615CTMissense_Mutationp.P564S1
ERBB2GBMchr173786666737866667GASilent1
ERBB2KIRCchr173787608737876087GCSplice_Sitep.S619_splice1
ERBB2LIHCchr173786468637864686C-Frame_Shift_Delp.A83fs1
ERBB2LUADchr173786634037866340GTSplice_Sitep.L185_splice1
ERBB2READchr173788285437882854AGMissense_Mutationp.E941G1
ERBB2CESCchr173787960337879603GCMissense_Mutationp.G660R1
ERBB2HNSCchr173786567637865676CTMissense_Mutation1
ERBB2BLCAchr173787210737872107CTSilent1
ERBB2BLCAchr173788404837884048CGSilentp.L1143L1
ERBB2COADchr173786466637864666GASilentp.Q76Q1
ERBB2ESCAchr173787961037879610TAMissense_Mutationp.L632Q1
ERBB2STADchr173788286337882863CTMissense_Mutationp.S974F1
ERBB2HNSCchr173788202237882022GAMissense_Mutationp.E930K1
ERBB2LIHCchr173787263037872630CTSilentp.N530N1
ERBB2PAADchr173788202437882024GTMissense_Mutation1
ERBB2PCPGchr173788017837880178CTMissense_Mutation1
ERBB2BLCAchr173788197937881979GCSilentp.L885L1
ERBB2COADchr173788162137881621GASilentp.R867R1
ERBB2SKCMchr173787159837871598TCMissense_Mutationp.L373P1
ERBB2GBMchr173787284437872844ATMissense_Mutation1
ERBB2THYMchr173786560037865600CTMissense_Mutation1
ERBB2BLCAchr173788425937884259GCMissense_Mutation1
ERBB2KIRCchr173788207837882078CASilentp.T918T1
ERBB2LIHCchr173786560537865605C-Frame_Shift_Delp.N128fs1
ERBB2LGGchr173787604937876049CTSilentp.D606D1
ERBB2LUADchr173788099737880998-TATIn_Frame_Insp.745_746insY1
ERBB2LUSCchr173788315837883158GCMissense_Mutationp.E1021Q1
ERBB2SARCchr173786478337864783CTSilent1
ERBB2BLCAchr173786821637868216CGMissense_Mutationp.L313V1
ERBB2CESCchr173788142537881425GAMissense_Mutationp.D873N1
ERBB2ESCAchr173786634237866342CTMissense_Mutationp.T216M1
ERBB2STADchr173787960137879601TAMissense_Mutationp.V659D1
ERBB2HNSCchr173788422937884229CTMissense_Mutation1
ERBB2BLCAchr173786325737863257GCMissense_Mutation1
ERBB2BLCAchr173787990337879903CTMissense_Mutationp.T703I1
ERBB2ESCAchr173788100037881000GAMissense_Mutationp.V747M1
ERBB2STADchr173786659237866592GTSplice_Site1
ERBB2HNSCchr173788018037880180GCMissense_Mutationp.D712H1
ERBB2BLCAchr173788099737880997GAMissense_Mutation1
ERBB2HNSCchr173788357837883578GCMissense_Mutationp.E1064Q1
ERBB2LIHCchr173786331537863315TCMissense_Mutationp.L49P1
ERBB2PRADchr173788101437881014TCSilentp.Y781Y1
ERBB2BLCAchr173788313437883134GCMissense_Mutationp.D983H1
ERBB2CESCchr173788286337882863CTMissense_Mutation1
ERBB2COADchr173788378737883787CTSilentp.C1103C1
ERBB2SKCMchr173788021937880219TAMissense_Mutationp.L725M1
ERBB2GBMchr173787961737879617CTSilent1
ERBB2BLCAchr173787283937872839CTMissense_Mutation1
ERBB2BLCAchr173788113237881132GCMissense_Mutation1
ERBB2KIRCchr173786635037866350GAMissense_Mutationp.V189I1
ERBB2LIHCchr173788198537881985T-Frame_Shift_Delp.T887fs1
ERBB2LGGchr173786557037865570GTSplice_Site1
ERBB2LUSCchr173786471337864713CTMissense_Mutationp.P122L1
ERBB2SARCchr173788312137883121GTSilent1
ERBB2BLCAchr173788026137880261GAMissense_Mutationp.D769N1
ERBB2CESCchr173787159337871593GCMissense_Mutationp.E401D1
ERBB2HNSCchr173788311337883113CTMissense_Mutation1
ERBB2BLCAchr173787982037879820GASilentp.A675A1
ERBB2ESCAchr173786557937865579AGMissense_Mutationp.K120E1
ERBB2HNSCchr173787267437872674GAMissense_Mutationp.R515Q1
ERBB2BLCAchr173786666237866662GTMissense_Mutation1
ERBB2BLCAchr173786559337865593GCMissense_Mutationp.L124F1
ERBB2HNSCchr173787962937879629GTSilentp.G668G1
ERBB2PRADchr173788371937883719CTMissense_Mutationp.R1081W1
ERBB2BLCAchr173786460337864603CGSilentp.L55L1
ERBB2CESCchr173786565937865659CTSilent1
ERBB2DLBCchr173787203537872035GTMissense_Mutationp.W452C1
ERBB2SKCMchr173786668637866686CTMissense_Mutationp.P255S1
ERBB2GBMchr173787968237879682CTMissense_Mutation1
ERBB2BLCAchr173787173137871731CTSilent1
ERBB2KIRCchr173787154937871550-CFrame_Shift_Insp.Q357fs1
ERBB2LIHCchr173788198937881989G-Frame_Shift_Delp.G889fs1
ERBB2LUSCchr173786673337866733CTSilentp.Y301_splice1
ERBB2SARCchr173788403737884037CGMissense_Mutation1
ERBB2BLCAchr173788404837884048CGSilentp.L1173L1
ERBB2CESCchr173788362337883623GAMissense_Mutationp.E1079K1
ERBB2HNSCchr173786634637866346CTSilent1
ERBB2BLCAchr173787210737872107CTSilentp.F446F1
ERBB2SKCMchr173786335537863355CTSilentp.L32L1
ERBB2ESCAchr173788102137881021CTMissense_Mutationp.R754C1
ERBB2TGCTchr173787962637879626GCMissense_Mutationp.L667F1
ERBB2BLCAchr173788104137881041GASilent1
ERBB2BLCAchr173786635937866359GTMissense_Mutationp.G192C1
ERBB2HNSCchr173787177037871770CTMissense_Mutationp.R432W1
ERBB2LIHCchr173788205837882058C-Frame_Shift_Delp.P912fs1
ERBB2LUADchr173788099737880998-TCTIn_Frame_Insp.745_746insS1
ERBB2PRADchr173788105037881050GASilentp.T763T1
ERBB2DLBCchr173786326837863268GASilentp.L33L1
ERBB2SKCMchr173786559737865597CTNonsense_Mutationp.Q126*1
ERBB2GBMchr173788137237881372GTMissense_Mutation1
ERBB2THYMchr173788142737881427CTSilentp.D873D1
ERBB2LUADchr173787603837876038ATSplice_Site1
ERBB2BLCAchr173787261837872618CGSilentp.T496T1
ERBB2HNSCchr173788290437882904GAMissense_Mutationp.V958I1
ERBB2LGGchr173788022437880224GTMissense_Mutation1
ERBB2OVchr173513465835134658GTMissense_Mutation1
ERBB2SARCchr173786478337864783CTSilentp.L115L1
ERBB2BLCAchr173788418037884180CTSilentp.F1217F1
ERBB2CESCchr173788425537884255GASilentp.T12421
ERBB2HNSCchr173788398237883982GASilent1
ERBB2BLCAchr173788104137881041GASilentp.L760L1
ERBB2SKCMchr173786338837863388CTSilentp.F43F1
ERBB2ESCAchr173786634237866342CTMissense_Mutationp.T186M1
ERBB2TGCTchr173788415237884152ACMissense_Mutationp.H1178P1
ERBB2BLCAchr173786565637865656GASilent1
ERBB2HNSCchr173786567637865676CTMissense_Mutationp.T182I1
ERBB2LIHCchr173788206437882064C-Frame_Shift_Delp.P915fs1
ERBB2LUADchr173788421737884218-GFrame_Shift_Insp.G1200fs1
ERBB2PRADchr173788417037884170GAMissense_Mutationp.S1184N1
ERBB2BLCAchr173786667137866671GCMissense_Mutationp.E250Q1
ERBB2GBMchr173788412437884124CAMissense_Mutation1
ERBB2THYMchr173788107537881075CTMissense_Mutationp.P772S1
ERBB2BLCAchr173786821637868216CGMissense_Mutation1
ERBB2BLCAchr173786644437866444CTMissense_Mutationp.S220F1
ERBB2LUADchr173787957637879576CGMissense_Mutationp.L621V1
ERBB2BLCAchr173786607837866078CTMissense_Mutation1
ERBB2BLCAchr173786325737863257GCMissense_Mutationp.D30H1
ERBB2LIHCchr173787216437872164CTSilent1
ERBB2OVchr173513514335135143GAMissense_Mutation1
ERBB2SARCchr173787603937876039GTSplice_Site1
ERBB2BLCAchr173787990337879903CTMissense_Mutationp.T733I1
ERBB2HNSCchr173788290437882904GAMissense_Mutation1
ERBB2BLCAchr173788026137880261GTMissense_Mutationp.D739Y1
ERBB2COADchr173786477637864776GAMissense_Mutationp.R113Q1
ERBB2SKCMchr173787607437876074GAMissense_Mutationp.E615K1
ERBB2ESCAchr173788132337881323GAMissense_Mutationp.V809M1
ERBB2TGCTchr173787959937879599GTSilentp.V628V1
ERBB2BLCAchr173788415137884151CTMissense_Mutation1
ERBB2HNSCchr173788422937884229CTMissense_Mutationp.P1234S1
ERBB2PAADchr173786829437868294GAMissense_Mutationp.A309T1
ERBB2LUADchr173787603837876038ATSplice_Sitep.S633_splice1
ERBB2PRADchr173786637237866372GAMissense_Mutationp.R196H1
ERBB2BLCAchr173788113237881132GCMissense_Mutationp.D791H1
ERBB2HNSCchr173788018037880180GCMissense_Mutation1
ERBB2THYMchr173788142737881427CTSilentp.D843D1
ERBB2BLCAchr173788425937884259GCMissense_Mutationp.E1214Q1
ERBB2KIRPchr173787608037876080ACSilentp.R617R1
ERBB2LUADchr173786820137868201GAMissense_Mutationp.V278M1

check buttonCopy number variation (CNV) of ERBB2
* Click on the image to open the original image in a new window.
all structure

check buttonFusion gene breakpoints (product of the structural variants (SVs)) across ERBB2
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


check button Fusion genes with this translation factor from FusionGDB2.0.
FusionGDB2 IDDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
101608N/AAX187163ABCC5chr3183716296-ERBB2chr1737870791+
101608HNSCTCGA-CV-5432-01AACACAchr1735472930-ERBB2chr1737863393-
101608HNSCTCGA-CV-5432-01AACACAchr1735479394-ERBB2chr1737863393-
101608BRCATCGA-A8-A08X-01AAP2B1chr1733968994+ERBB2chr1737844949+
101608BRCATCGA-A8-A08X-01AAP2B1chr1733968994+ERBB2chr1737849514+
101608N/ADL055715ASH1Lchr1155446335-ERBB2chr1737884815-
101608STADTCGA-BR-4357CAB39chr2231577945+ERBB2chr1737863242+
101608BRCATCGA-D8-A1XJ-01ACACNB1chr1737334237-ERBB2chr1737886276+
101608LUSCTCGA-L3-A524-01ACASC3chr1738297860+ERBB2chr1737844949+
101608BRCATCGA-A8-A08XCDK12chr1737657692+ERBB2chr1737851240+
101608BRCATCGA-A8-A08X-01ACDK12chr1737657692+ERBB2chr1737851241+
101608BRCATCGA-C8-A12Q-01ACORO1Bchr1167207589-ERBB2chr1737868181+
101608STADTCGA-CD-5799-01ACPDchr1728706532+ERBB2chr1737875611+
101608BRCATCGA-BH-A1F2-01AEME1chr1748452873+ERBB2chr1737882815+
27204BRCATCGA-C8-A132-01AERBB2chr1737881655+ABI3chr1747293893+
27204BRCATCGA-C8-A132-01AERBB2chr1737882106+ABI3chr1747293893+
85929BRCATCGA-AO-A0JM-01AERBB2chr1737868701+ARL5Cchr1737321392-
100579N/ABI045492ERBB2chr1737874310-CD99chrY2586265-
99264BRCATCGA-BH-A204ERBB2chr1737868701+CDK12chr1737680926+
99264BRCATCGA-BH-A204-01AERBB2chr1737868701+CDK12chr1737680927+
99264BRCATCGA-E2-A1LE-01AERBB2chr1737866734+CDK12chr1737712539+
99264STADTCGA-BR-8289-01AERBB2chr1737886762+CDK12chr1737667831+
99264UCECTCGA-EO-A2CG-01AERBB2chr1737873733+CDK12chr1737721013+
82922BRCATCGA-UU-A93S-01AERBB2chr1737884915-CLDN7chr177166264-
85705UCECTCGA-D1-A3JP-01AERBB2chr1737863394+CNIH4chr1224553581+
85705UCECTCGA-D1-A3JP-01AERBB2chr1737866134+CNIH4chr1224553581+
85705UCECTCGA-D1-A3JP-01AERBB2chr1737866734+CNIH4chr1224553581+
87284BLCATCGA-4Z-AA7S-01AERBB2chr1737872192+CTTNchr1170269046+
86610COADTCGA-D5-6531-01AERBB2chr1737844531+DNAJC7chr1740134419-
93134STADTCGA-BR-A4PEERBB2chr1737868300+EIF1chr1739846029+
93134STADTCGA-BR-A4PEERBB2chr1737868701+EIF1chr1739846029+
93134STADTCGA-BR-A4PE-01AERBB2chr1737868701+EIF1chr1739846030+
78034STADTCGA-RD-A7BT-01AERBB2chr1737856564+FKBP10chr1739974341+
78034STADTCGA-RD-A7BT-01AERBB2chr1737866734+FKBP10chr1739977906+
102980STADTCGA-FP-8210-01AERBB2chr1737872192+GUK1chr1228333727+
101785BRCATCGA-D8-A1XJ-01AERBB2chr1737882868+HIAT1chr1100534041+
103189CESCTCGA-C5-A2LX-01AERBB2chr1737872858+IKZF3chr1737985741-
103189ESCATCGA-R6-A8W5-01BERBB2chr1737849578+IKZF3chr1737914218-
103189HNSCTCGA-CN-A49C-01AERBB2chr1737873733+IKZF3chr1737949186-
103189OVTCGA-25-1320-01AERBB2chr1737873733+IKZF3chr1737914218-
103189READTCGA-EI-6509ERBB2chr1737866134+IKZF3chr1737988404-
103189STADTCGA-D7-8573-01AERBB2chr1737886516+IKZF3chr1737949186-
103189UCECTCGA-B5-A3S1-01AERBB2chr1737879913+IKZF3chr1737944627-
99272Non-CancerTCGA-V5-A7RE-11AERBB2chr1737872192+JUPchr1739911684-
87242STADTCGA-BR-A4IZERBB2chr1737872192+KAT2Achr1740267053-
88945ESCATCGA-M9-A5M8ERBB2chr1737851434+KRT10chr1738977369-
88945ESCATCGA-M9-A5M8ERBB2chr1737856564+KRT10chr1738977369-
57254STADTCGA-CG-4466-01AERBB2chr1737868701+KRT24chr1738858185-
86250STADTCGA-BR-8483-01AERBB2chr1737856564+KRT39chr1739116662-
99417BRCATCGA-D8-A1XJ-01AERBB2chr1737873733+MED1chr1737571592-
97197STADTCGA-VQ-AA6GERBB2chr1737876087+MIEN1chr1737886544-
96452OVTCGA-20-1686ERBB2chr1737872192+MUC1chr1155159850-
90848BRCATCGA-BH-A1ENERBB2chr1737866134+NARS2chr1178147860-
90848BRCATCGA-BH-A1ENERBB2chr1737866734+NARS2chr1178147860-
90848BRCATCGA-BH-A1EN-01AERBB2chr1737866733+NARS2chr1178147859-
71237CESCTCGA-DS-A7WFERBB2chr1737856564+NEUROD2chr1737762857-
71237CESCTCGA-DS-A7WF-01AERBB2chr1737856563+NEUROD2chr1737762856-
71237CESCTCGA-VS-A9ULERBB2chr1737851434+NEUROD2chr1737764318-
71237CESCTCGA-VS-A9ULERBB2chr1737856564+NEUROD2chr1737764318-
71237CESCTCGA-VS-A9ULERBB2chr1737866134+NEUROD2chr1737764318-
100884BRCATCGA-C8-A137-01AERBB2chr1737863394+NFE2L2chr2178098999-
98627UCECTCGA-EY-A54A-01AERBB2chr1737884523+NOL12chr2238077874+
100918N/ACV340327ERBB2chr1737884125+NOMO1chr1614976494+
27204STADTCGA-FP-8211-01AERBB2chr1737872192+NUDT8chr1167396522-
99077CESCTCGA-Q1-A73RERBB2chr1737851434+PGAP3chr1737830932-
99077CESCTCGA-Q1-A73R-01AERBB2chr1737851433+PGAP3chr1737830931-
99077ESCATCGA-2H-A9GFERBB2chr1737856564+PGAP3chr1737830932-
99077ESCATCGA-2H-A9GFERBB2chr1737856564+PGAP3chr1737841002-
99077ESCATCGA-2H-A9GFERBB2chr1737856564+PGAP3chr1737842272-
99077UCECTCGA-FI-A2F8ERBB2chr1737866734+PGAP3chr1737842272-
89643CESCTCGA-Q1-A73RERBB2chr1737851434+PNMTchr1737825881+
103131BLCATCGA-DK-A1A3-01AERBB2chr1737866734+PPP1R1Bchr1737790136+
103131BRCATCGA-C8-A12Z-01AERBB2chr1737872192+PPP1R1Bchr1737790136+
103131CESCTCGA-4J-AA1J-01AERBB2chr1737856564+PPP1R1Bchr1737790136+
103131CESCTCGA-Q1-A73RERBB2chr1737883256+PPP1R1Bchr1737791859+
103131CESCTCGA-Q1-A73RERBB2chr1737883800+PPP1R1Bchr1737791859+
103131CESCTCGA-Q1-A73R-01AERBB2chr1737883255+PPP1R1Bchr1737791859+
103131CESCTCGA-Q1-A73R-01AERBB2chr1737883256+PPP1R1Bchr1737791860+
103131CESCTCGA-Q1-A73R-01AERBB2chr1737883799+PPP1R1Bchr1737791859+
103131CESCTCGA-Q1-A73R-01AERBB2chr1737883800+PPP1R1Bchr1737791860+
103131LUSCTCGA-22-0944-01AERBB2chr1737876087+PPP1R1Bchr1737792069+
103131OVTCGA-24-2033-01AERBB2chr1737856564+PPP1R1Bchr1737785423+
103131STADTCGA-RD-A7BT-01AERBB2chr1737886516+PPP1R1Bchr1737783559+
86255BRCATCGA-A2-A1G1-01AERBB2chr1737879913+PSMB3chr1736920372+
86255ESCATCGA-JY-A6FAERBB2chr1737876087+PSMB3chr1736916683+
86255ESCATCGA-JY-A6FA-01AERBB2chr1737876087+PSMB3chr1736916684+
86255ESCATCGA-L5-A88VERBB2chr1737873733+PSMB3chr1736916683+
86255ESCATCGA-L5-A88VERBB2chr1737876087+PSMB3chr1736918663+
99282STADTCGA-BR-8059-01AERBB2chr1737863394+PSMD3chr1738144936+
102270UCECTCGA-EY-A3QX-01AERBB2chr1737873733+PVT1chr8129082406+
102270UCECTCGA-EY-A3QX-01AERBB2chr1737873733+PVT1chr8129108764+
102270UCECTCGA-EY-A3QX-01AERBB2chr1737873733+PVT1chr8129108767+
102270UCECTCGA-EY-A3QX-01AERBB2chr1737876086+PVT1chr8129043188+
102270UCECTCGA-EY-A3QX-01AERBB2chr1737876086+PVT1chr8129043282+
102270UCECTCGA-EY-A3QX-01AERBB2chr1737876087+PVT1chr8129082406+
102270UCECTCGA-EY-A3QX-01AERBB2chr1737876087+PVT1chr8129108764+
79988N/AAW371253ERBB2chr1737881986+RABGAP1chr9125852605+
27204UCECTCGA-AP-A053-01AERBB2chr1737881398+RARRES2chr7150037762-
83930BRCATCGA-C8-A8HP-01AERBB2chr1737856564+SDF4chr11159348-
100123BRCATCGA-AR-A254ERBB2chr1737883256+SLC29A3chr1073121710+
100123BRCATCGA-AR-A254-01AERBB2chr1737883255+SLC29A3chr1073121710+
100123BRCATCGA-AR-A254-01AERBB2chr1737883256+SLC29A3chr1073121711+
97282BRCATCGA-A2-A0YE-01AERBB2chr1737871789-SLC39A11chr1771084914-
93086BRCATCGA-A2-A3XZ-01AERBB2chr1737884002+SMARCE1chr1738787057-
85104BRCATCGA-BH-A1EV-01AERBB2chr1737872192+SRCIN1chr1736699371-
99287CESCTCGA-Q1-A73RERBB2chr1737866734+STARD3chr1737815303+
99287CESCTCGA-Q1-A73R-01AERBB2chr1737866733+STARD3chr1737815303+
99287CESCTCGA-Q1-A73R-01AERBB2chr1737872857+STARD3chr1737809733+
99287CESCTCGA-Q1-A73R-01AERBB2chr1737873732+STARD3chr1737809733+
99287ESCATCGA-M9-A5M8ERBB2chr1737872858+STARD3chr1737816463+
99287STADTCGA-CD-5799-01AERBB2chr1737856564+STARD3chr1737809734+
97624BRCATCGA-BH-A0DZ-11AERBB2chr1737881654+STXBP4chr1753065831-
97624BRCATCGA-BH-A0DZ-11AERBB2chr1737881847+STXBP4chr1753065852-
98320LUADTCGA-69-7761-01AERBB2chr1737884915-SUPT16Hchr1421829491-
92224BLCATCGA-DK-A2I6-01AERBB2chr1737868701+TATDN1chr8125507783-
76256LUSCTCGA-56-A4BYERBB2chr1737872858+TCAPchr1737821626+
76256LUSCTCGA-56-A4BYERBB2chr1737873451+TCAPchr1737821131+
76256LUSCTCGA-56-A4BY-01AERBB2chr1737872858+TCAPchr1737821969+
99290BRCATCGA-GM-A2DA-01AERBB2chr1737880176+THRAchr1738233860-
99295STADTCGA-D7-8573ERBB2chr1737873733+WIPF2chr1738412642+
99295STADTCGA-D7-8573-01AERBB2chr1737873733+WIPF2chr1738412643+
99422STADTCGA-VQ-A8DZ-01AERBB2chr1737884055+WSB1chr1725628814+
99422STADTCGA-VQ-A8DZ-01AERBB2chr1737884130+WSB1chr1725625630+
99422STADTCGA-VQ-A8DZ-01AERBB2chr1737884131+WSB1chr1725625631+
102744BRCATCGA-OL-A5RY-01AERBB2chr1737866734+ZANchr7100392818+
99298STADTCGA-BR-A4PEERBB2chr1737882106+ZPBP2chr1738026946+
101608BRCATCGA-A8-A09I-01AFBXL20chr1737557614-ERBB2chr1737863243+
101608STADTCGA-BR-8483-01AFKBP10chr1739969531+ERBB2chr1737855790+
101608BRCATCGA-D8-A1X5-01AGPR125chr422475395-ERBB2chr1737844949+
101608BRCATCGA-D8-A1X5-01AGPR125chr422475395-ERBB2chr1737849514+
101608BLCATCGA-GU-AATPGRB7chr1737894386+ERBB2chr1737844949+
101608BRCATCGA-C8-A1HK-01AGRB7chr1737902253+ERBB2chr1737883942+
101608CESCTCGA-C5-A1M9-01AGRB7chr1737902455+ERBB2chr1737849514+
101608CESCTCGA-LP-A5U3-01AGRB7chr1737897160+ERBB2chr1737879791+
101608CESCTCGA-LP-A5U3-01AGRB7chr1737898709+ERBB2chr1737855790+
101608CESCTCGA-LP-A5U3-01AGRB7chr1737898709+ERBB2chr1737863243+
101608CESCTCGA-VS-A9V5GRB7chr1737894386+ERBB2chr1737886276+
101608CESCTCGA-VS-A9V5GRB7chr1737894645+ERBB2chr1737886276+
101608ESCATCGA-V5-A7REKIAA0100chr1726958497-ERBB2chr1737849514+
101608..MDKchr1146404136+ERBB2chr1746404136+
101608BRCATCGA-BH-A1EVMED24chr1738188901-ERBB2chr1737868574+
101608STADTCGA-HU-A4G6MED24chr1738185078-ERBB2chr1737865570+
101608STADTCGA-EQ-8122MIB2chr11551994+ERBB2chr1737863242+
101608CESCTCGA-EK-A2RM-01AMIEN1chr1737885540-ERBB2chr1737863243+
101608BLCATCGA-DK-A2I6MTSS1chr8125740124-ERBB2chr1737863242+
101608BLCATCGA-DK-A2I6-01AMTSS1chr8125740125-ERBB2chr1737863243+
101608BRCATCGA-C8-A275-01AMYO18Achr1727464034-ERBB2chr1737879572+
101608BRCATCGA-C8-A275-01AMYO18Achr1727492960-ERBB2chr1737879791+
101608BLCATCGA-2F-A9KPPGAP3chr1737844086-ERBB2chr1737844948+
101608BLCATCGA-2F-A9KP-01APGAP3chr1737840850-ERBB2chr1737883942+
101608CESCTCGA-DS-A7WF-01APGAP3chr1737837498-ERBB2chr1737883650-
101608CESCTCGA-VS-A9V0-01APGAP3chr1737840850-ERBB2chr1737880979+
101608ESCATCGA-L5-A8NJPGAP3chr1737840849-ERBB2chr1737844948+
101608ESCATCGA-L5-A8NJPGAP3chr1737840850-ERBB2chr1737844949+
101608ESCATCGA-L5-A8NJPGAP3chr1737840850-ERBB2chr1737849514+
101608STADTCGA-D7-6822-01APGAP3chr1737842175-ERBB2chr1737844949+
101608BRCATCGA-A8-A08X-01APIP4K2Bchr1736955519-ERBB2chr1737855790+
101608N/ABE696969PLECchr8145012593-ERBB2chr1737864712-
101608BRCATCGA-D8-A1XJ-01APLXDC1chr1737306531-ERBB2chr1737868700-
101608N/ABF837831PPFIA3chr1949653673-ERBB2chr1737881146-
101608BRCATCGA-UL-AAZ6-01APPP1R1Bchr1737783927+ERBB2chr1737879912-
101608BRCATCGA-UL-AAZ6-01APPP1R1Bchr1737783962+ERBB2chr1737879912-
101608ESCATCGA-L5-A88VPSMB3chr1736916703+ERBB2chr1737872634+
101608ESCATCGA-L5-A88VPSMB3chr1736916746+ERBB2chr1737873665+
101608ESCATCGA-L5-A88VPSMB3chr1736916751+ERBB2chr1737872131+
101608ESCATCGA-L5-A88VPSMB3chr1736918690+ERBB2chr1737866433+
101608ESCATCGA-L5-A88VPSMB3chr1736920430+ERBB2chr1737873594+
101608ESCATCGA-L5-A88VPSMB3chr1736920433+ERBB2chr1737872612+
101608ESCATCGA-L5-A88VPSMB3chr1736920471+ERBB2chr1737871734+
101608BRCATCGA-E2-A152-01ASLC2A1chr143392014-ERBB2chr1737868586+
101608LUADTCGA-44-A4SS-01AST14chr11130059791+ERBB2chr1737873573+
101608N/ABF229957TMEM177chr2120473042+ERBB2chr1737866403-
101608STADTCGA-R5-A7ZEWIPF2chr1738421398+ERBB2chr1737872553+
101608STADTCGA-R5-A7ZE-01BWIPF2chr1738421398+ERBB2chr1737872554+
101620..ZNF207chr1730683717ERBB2chr1737873369


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Prognostic Analysis


check button Kaplan-Meier plots with logrank tests of overall survival (OS)
all structure
Cancer typeTranslation factorCoefficentHazard ratioWald test pvalLikelihool ratio pvalLogrank test pval# samples


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Translation factor and Gender


check button Differential gene expression between female and male. (Wilcoxon test, pval<0.05)
all structure
Cancer typeTranslation factorpvaladj.p
STADERBB20.0008809295683065670.024
TGCTERBB24.89135747722409e-050.0014

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Translation factor and Age


check button Differential gene expression between young and old age groups (Wilcoxon test, pval<0.05)
all structure
Cancer typeTranslation factorpvaladj.p
TGCTERBB20.03690152242512321
LUSCERBB20.0225691260712670.68
GBMERBB20.02180699782332430.68
LGGERBB21.54296043607822e-095.1e-08
ESCAERBB20.02408736941790420.7
PCPGERBB20.01535550141580340.49
THYMERBB20.03248222737135680.91

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Related Drugs


check button Drugs targeting genes involved in this translation factor.
(DrugBank Version 5.1.8 2021-05-08)
UniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
P04626DB00072TrastuzumabAntibodyBiotechApproved|Investigational
P04626DB01259LapatinibAntagonistSmall moleculeApproved|Investigational
P04626DB04988IGN311BiotechInvestigational
P04626DB05773Trastuzumab emtansineAntibodyBiotechApproved|Investigational
P04626DB05944VarlitinibSmall moleculeInvestigational
P04626DB06021AV-412Small moleculeInvestigational
P04626DB06366PertuzumabInhibitorBiotechApproved
P04626DB08916AfatinibInhibitorSmall moleculeApproved
P04626DB11652TucatinibInhibitorSmall moleculeApproved|Investigational
P04626DB11973TesevatinibSmall moleculeInvestigational
P04626DB12267BrigatinibInhibitorSmall moleculeApproved|Investigational
P04626DB14967MargetuximabAntagonistBiotechInvestigational
P04626DB15035ZanubrutinibInhibitorSmall moleculeApproved|Investigational
P04626DB00072TrastuzumabAntibody
P04626DB01259LapatinibAntagonist
P04626DB04988IGN311
P04626DB05773Trastuzumab emtansineAntibody
P04626DB05944Varlitinib
P04626DB06021AV-412
P04626DB06366PertuzumabInhibitor
P04626DB08916AfatinibInhibitor
P04626DB11652TucatinibInhibitor
P04626DB11973Tesevatinib
P04626DB12267BrigatinibInhibitor
P04626DB14967MargetuximabAntagonist
P04626DB15035ZanubrutinibInhibitor

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Related Diseases


check button Diseases associated with this translation factor.
(DisGeNet 4.0)
Disease IDDisease Name# PubMedsDisease source
C0006142Malignant neoplasm of breast40CGI;CTD_human
C0678222Breast Carcinoma40CGI;CTD_human
C1257931Mammary Neoplasms, Human40CTD_human
C4704874Mammary Carcinoma, Human40CTD_human
C1140680Malignant neoplasm of ovary4CGI;CTD_human;UNIPROT
C0024623Malignant neoplasm of stomach3CGI;CTD_human
C0376358Malignant neoplasm of prostate3CTD_human
C1708349Hereditary Diffuse Gastric Cancer3CTD_human
C0205641Adenocarcinoma, Basal Cell2CTD_human
C0205642Adenocarcinoma, Oxyphilic2CTD_human
C0205643Carcinoma, Cribriform2CTD_human
C0205644Carcinoma, Granular Cell2CTD_human
C0205645Adenocarcinoma, Tubular2CTD_human
C0699791Stomach Carcinoma2CGI;UNIPROT
C0919267ovarian neoplasm2CGI;CTD_human
C0007102Malignant tumor of colon1CTD_human
C0007134Renal Cell Carcinoma1CTD_human
C0013930Embolism, Tumor1CTD_human
C0016978gallbladder neoplasm1CTD_human
C0021367Mammary Ductal Carcinoma1CTD_human
C0024232Lymphatic Metastasis1CTD_human
C0025149Medulloblastoma1CTD_human
C0030354Papilloma1CTD_human
C0153452Malignant neoplasm of gallbladder1CTD_human
C0205833Medullomyoblastoma1CTD_human
C0205874Papilloma, Squamous Cell1CTD_human
C0205875Papillomatosis1CTD_human
C0206698Cholangiocarcinoma1CTD_human
C0242379Malignant neoplasm of lung1CTD_human
C0278510Childhood Medulloblastoma1CTD_human
C0278876Adult Medulloblastoma1CTD_human
C0279702Conventional (Clear Cell) Renal Cell Carcinoma1CTD_human
C0345905Intrahepatic Cholangiocarcinoma1CTD_human
C0546837Malignant neoplasm of esophagus1CTD_human
C0684249Carcinoma of lung1UNIPROT
C0685938Malignant neoplasm of gastrointestinal tract1CTD_human
C0751291Desmoplastic Medulloblastoma1CTD_human
C1134719Invasive Ductal Breast Carcinoma1CTD_human
C1257925Mammary Carcinoma, Animal1CTD_human
C1266042Chromophobe Renal Cell Carcinoma1CTD_human
C1266043Sarcomatoid Renal Cell Carcinoma1CTD_human
C1266044Collecting Duct Carcinoma of the Kidney1CTD_human
C1275668Melanotic medulloblastoma1CTD_human
C1306837Papillary Renal Cell Carcinoma1CTD_human
C1368275Pigmented Basal Cell Carcinoma1CTD_human
C2931822Nasopharyngeal carcinoma1CTD_human
C3805278Extrahepatic Cholangiocarcinoma1CTD_human
C4721610Carcinoma, Ovarian Epithelial1CTD_human
C4721806Carcinoma, Basal Cell1CTD_human