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	Gene Summary
	Translation studies in PubMed
	Exon Skipping Events
	Expression
	Expression Regulation
	Associated Genes
	Protein 3D Structure
	Protein-Protein Interaction
	Mutations
	Prognostic Analysis
	Gender Association
	Age Association
	Related Drugs
	Related Diseases

Translation Factor: RPL36 (NCBI Gene ID:25873)

Gene Summary

Gene Summary

Gene Information	Gene Name: RPL36
	Gene ID: 25873
	Gene Symbol	RPL36
	Gene ID	25873
	Gene Name	ribosomal protein L36
	Synonyms	L36
	Cytomap	19p13.3
	Type of Gene	protein-coding
	Description	60S ribosomal protein L36large ribosomal subunit protein eL36
	Modification date	20200313
	UniProtAcc	Q9Y3U8

Child GO biological process term(s) under GO:0006412

GO ID	GO term
GO:0005840	Ribosome
GO:0002181	Cytoplasmic translation
GO:0006412	Translation

Gene ontology of translaction factor with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	RPL36	GO:0002181	cytoplasmic translation	25957688

Inferred gene age of translation factor.

Gene	Inferred gene age group among (0 - 67.6], (67.6 - 355.7], (355.7 - 733], (733 - 1119.25], >1119.25
RPL36	>1119.25

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Translation Studies in PubMed

We searched PubMed using 'RPL36[title] AND translation [title] AND human.'

Gene	Title	PMID
RPL36	.	.

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Exon Skipping Events

Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
For more annotations, please visit our ExonSkipDB.

Open reading frame (ORF) analsis of exon skipping events based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ENST	Exon skip start (DNA)	Exon Skip end (DNA)	ORF
ENST00000347512	5690516	5690611	5CDS-5UTR
ENST00000577222	5690516	5690611	5CDS-5UTR
ENST00000347512	5691329	5691464	In-frame
ENST00000394580	5691329	5691464	In-frame
ENST00000577222	5691329	5691464	In-frame
ENST00000579649	5691329	5691464	In-frame

Exon skipping position in the amino acid sequence.

ENST	Exon skip start (DNA)	Exon Skip end (DNA)	Len(transcript seq)	Exon skip start (mRNA)	Exon Skip end (mRNA)	Len(amino acid seq)	Exon skip start (AA)	Exon Skip end (AA)
ENST00000579649	5691329	5691464	466	179	313	105	31	76
ENST00000394580	5691329	5691464	573	286	420	105	31	76
ENST00000347512	5691329	5691464	724	228	362	105	31	76
ENST00000577222	5691329	5691464	891	638	772	105	31	76

Potentially (partially) lost protein functional features of UniProt.

UniProtAcc	Exon skip start (AA)	Exon Skip end (AA)	Function feature start (AA)	Function feature end (AA)	Functional feature type	Functional feature desc.
Q9Y3U8	31	76	2	105	Chain	ID=PRO_0000195007;Note=60S ribosomal protein L36
Q9Y3U8	31	76	2	105	Chain	ID=PRO_0000195007;Note=60S ribosomal protein L36
Q9Y3U8	31	76	2	105	Chain	ID=PRO_0000195007;Note=60S ribosomal protein L36
Q9Y3U8	31	76	2	105	Chain	ID=PRO_0000195007;Note=60S ribosomal protein L36
Q9Y3U8	31	76	62	62	Modified residue	Note=N6-acetyllysine;Ontology_term=ECO:0000244;evidence=ECO:0000244\|PubMed:19608861;Dbxref=PMID:19608861
Q9Y3U8	31	76	62	62	Modified residue	Note=N6-acetyllysine;Ontology_term=ECO:0000244;evidence=ECO:0000244\|PubMed:19608861;Dbxref=PMID:19608861
Q9Y3U8	31	76	62	62	Modified residue	Note=N6-acetyllysine;Ontology_term=ECO:0000244;evidence=ECO:0000244\|PubMed:19608861;Dbxref=PMID:19608861
Q9Y3U8	31	76	62	62	Modified residue	Note=N6-acetyllysine;Ontology_term=ECO:0000244;evidence=ECO:0000244\|PubMed:19608861;Dbxref=PMID:19608861
Q9Y3U8	31	76	67	67	Natural variant	ID=VAR_051804;Note=K->E;Dbxref=dbSNP:rs11556110
Q9Y3U8	31	76	67	67	Natural variant	ID=VAR_051804;Note=K->E;Dbxref=dbSNP:rs11556110
Q9Y3U8	31	76	67	67	Natural variant	ID=VAR_051804;Note=K->E;Dbxref=dbSNP:rs11556110
Q9Y3U8	31	76	67	67	Natural variant	ID=VAR_051804;Note=K->E;Dbxref=dbSNP:rs11556110

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Expression

Gene expression level across TCGA pancancer

Gene expression level across GTEx pantissue

Expression level of gene isoforms across TCGA pancancer

Expression level of gene isoforms across GTEx pantissue

Cancer(tissue) type-specific expression level of Translation factor using z-score distriution

Differential expression between tumor and matched normal (in the cancer types with more than 10 matched samples)

Cancer type	Translation factor	FC	adj.pval
LUSC	RPL36	-2.06002981714578	0.000251881966259792
PRAD	RPL36	2.08473274747086	0.000648342999076925
KICH	RPL36	-3.14173884697974	0.00612920522689819
HNSC	RPL36	-3.50943950068052	0.0448960527075997
KIRC	RPL36	-1.94758136221802	1.67069036077484e-10
KIRP	RPL36	-1.416442430054	2.31293961405754e-06
COAD	RPL36	3.04198777530358	5.1647424697876e-05
THCA	RPL36	-3.58350995246394	5.65302269188786e-05

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Expression Regulation

Translation factor expression regulation through miRNA binding

Cancer type

Gene

miRNA

TargetScan binding score (Context++ score percentile)

Coefficient

Pvalue

Translation factor expression regulation through methylation in the promoter of Translation factor

Cancer type	Gene	methyl group b	methyl group a	DEG pval	avg methyl in b	avg methyl in a	avg exp in b	avg exp in a
LAML	RPL36	3	2	0.00809421030344664	0.619725965447155	0.577743191964286	0.609673210034574	0.72755946874551
SARC	RPL36	3	2	0.00133440132525964	0.620817692307692	0.520557676861291	-0.6048414241116	-0.195308693188178

Translation factor expression regulation through methylation in the gene body of Translation factor (positive regulation)

Cancer type	Gene	methyl group b	methyl group a	DEG pval	avg methyl in b	avg methyl in a	avg exp in b	avg exp in a
ACC	RPL36	2	3	0.0089858844274834	0.525201278772379	0.645467379679144	-0.455912085023558	-1.76464014826509

Translation factor expression regulation through copy number variation of Translation factor

Cancer type	Gene	Coefficient	Pvalue
ESCA	RPL36	0.026727157	0.00444972
KIRC	RPL36	-0.045380786	0.010785928
DLBC	RPL36	-0.013322312	0.047673327

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Associated Genes

Strongly correlated genes belong to cellular important gene groups with RPL36 (coefficient>0.8, pval<0.05, node color based on FC between tumor and matched normal). Significantly associated important genes in the individual cancer types. * Cell metabolism gene: cell metabolism genes from REACTOME (black edge), IUPHAR: drug target genes from IUPHAR (blue edge), Kinase: human kinase genes (brown edge), CGC: cancer gene census genes (orange edge), TSG: tumor suppresor genes (purple edge), Epifactor: epigenetic factors (light blue edge), TF: transcription factors (green)

Cancer type	Gene group	Translation factor	Correlated gene	Coefficient	Pvalue
CHOL	Cell metabolism gene	RPL36	SNRPD2	0.852556287	1.07E-13
CHOL	Cell metabolism gene	RPL36	PFDN5	0.864852448	1.88E-14
CHOL	CGC	RPL36	NACA	0.8539359	8.90E-14
CHOL	Epifactor	RPL36	FBL	0.83638436	8.49E-13
CHOL	TSG	RPL36	GLTSCR2	0.813586227	1.10E-11
CHOL	TSG	RPL36	GNB2L1	0.827211643	2.49E-12
DLBC	Cell metabolism gene	RPL36	PGLS	0.804016027	5.93E-12
DLBC	Cell metabolism gene	RPL36	DGUOK	0.805343117	5.15E-12
DLBC	Cell metabolism gene	RPL36	PSMD13	0.80918643	3.40E-12
DLBC	Cell metabolism gene	RPL36	TOMM7	0.812242838	2.43E-12
DLBC	Cell metabolism gene	RPL36	PTDSS2	0.816061936	1.58E-12
DLBC	Cell metabolism gene	RPL36	PFDN4	0.816528163	1.50E-12
DLBC	Cell metabolism gene	RPL36	POLR2J	0.817609504	1.33E-12
DLBC	Cell metabolism gene	RPL36	POLR2I	0.819392952	1.08E-12
DLBC	Cell metabolism gene	RPL36	POLR2L	0.81960782	1.05E-12
DLBC	Cell metabolism gene	RPL36	PSMC5	0.822320477	7.67E-13
DLBC	Cell metabolism gene	RPL36	TIMM13	0.823940055	6.33E-13
DLBC	Cell metabolism gene	RPL36	PSMB3	0.827787578	3.98E-13
DLBC	Cell metabolism gene	RPL36	POLR2F	0.830347952	2.90E-13
DLBC	Cell metabolism gene	RPL36	GEMIN7	0.835876336	1.44E-13
DLBC	Cell metabolism gene	RPL36	TOMM22	0.842791073	5.80E-14
DLBC	Cell metabolism gene	RPL36	GFER	0.854062164	1.19E-14
DLBC	Cell metabolism gene	RPL36	TIMM9	0.864270233	2.52E-15
DLBC	Cell metabolism gene	RPL36	NME2	0.876672829	3.20E-16
DLBC	Cell metabolism gene	RPL36	SNRPD2	0.898787935	4.34E-18
DLBC	Cell metabolism gene	RPL36	PFDN5	0.908172905	5.14E-19
DLBC	Cell metabolism gene	RPL36	FAU	0.916534486	6.26E-20
DLBC	CGC	RPL36	HRAS	0.80778897	3.96E-12
DLBC	CGC	RPL36	NACA	0.861028287	4.19E-15
DLBC	Epifactor	RPL36	DMAP1	0.812633686	2.33E-12
DLBC	Epifactor	RPL36	ZNHIT1	0.813086309	2.21E-12
DLBC	Epifactor	RPL36	FBL	0.830099898	3.00E-13
DLBC	Epifactor	RPL36	TAF10	0.838259478	1.06E-13
DLBC	IUPHAR	RPL36	HRAS	0.80778897	3.96E-12
DLBC	TF	RPL36	REXO4	0.809511385	3.28E-12
DLBC	TF	RPL36	ZNF581	0.809519111	3.28E-12
DLBC	TF	RPL36	THAP3	0.826600981	4.60E-13
DLBC	TF	RPL36	ZNF444	0.834181666	1.79E-13
DLBC	TF	RPL36	THAP7	0.834915578	1.63E-13
DLBC	TF	RPL36	THAP4	0.844949203	4.33E-14
DLBC	TF	RPL36	NME2	0.876672829	3.20E-16
DLBC	TSG	RPL36	GLTSCR2	0.813249011	2.17E-12
DLBC	TSG	RPL36	TSSC4	0.823138226	6.97E-13
DLBC	TSG	RPL36	PARK7	0.826306989	4.77E-13
DLBC	TSG	RPL36	GADD45GIP1	0.886436726	5.35E-17
DLBC	TSG	RPL36	GNB2L1	0.906918117	6.92E-19
GBM	Cell metabolism gene	RPL36	SSR2	0.804831422	2.30E-40
GBM	Cell metabolism gene	RPL36	GEMIN7	0.816028103	2.53E-42
GBM	Cell metabolism gene	RPL36	PFDN5	0.824775588	5.98E-44
GBM	Cell metabolism gene	RPL36	FAU	0.835577028	4.37E-46
GBM	Cell metabolism gene	RPL36	SNRPD2	0.844484171	5.74E-48
GBM	TSG	RPL36	GADD45GIP1	0.857461847	6.23E-51
KICH	Cell metabolism gene	RPL36	SNRPB	0.832757663	1.41E-24
KICH	Cell metabolism gene	RPL36	SNRPD2	0.854002411	5.46E-27
KICH	TF	RPL36	ZNF581	0.820929386	2.25E-23
KICH	TSG	RPL36	GLTSCR2	0.800249338	1.80E-21
KIRP	Cell metabolism gene	RPL36	POLR2I	0.803791478	2.20E-74
KIRP	Cell metabolism gene	RPL36	PGLS	0.805889893	4.70E-75
KIRP	Cell metabolism gene	RPL36	SNRPD2	0.87964957	1.27E-105
KIRP	Cell metabolism gene	RPL36	FAU	0.8993652	2.25E-117
KIRP	Epifactor	RPL36	FBL	0.815175083	4.05E-78
KIRP	TSG	RPL36	GADD45GIP1	0.826544857	4.09E-82
LGG	Cell metabolism gene	RPL36	FAU	0.837150908	1.83E-140
LIHC	Cell metabolism gene	RPL36	PFDN5	0.829769554	1.09E-108
LIHC	TSG	RPL36	GADD45GIP1	0.845933492	5.16E-117
MESO	Cell metabolism gene	RPL36	FAU	0.803821561	7.15E-21
PAAD	Cell metabolism gene	RPL36	FAU	0.854188498	2.70E-53
PCPG	Cell metabolism gene	RPL36	PFDN5	0.824559544	1.23E-47
PCPG	TSG	RPL36	GNB2L1	0.81857202	2.04E-46
PRAD	Cell metabolism gene	RPL36	POLR2H	0.810027792	3.89E-129
PRAD	Cell metabolism gene	RPL36	TIMM9	0.816881879	4.61E-133
PRAD	Cell metabolism gene	RPL36	TOMM7	0.824976196	6.44E-138
PRAD	Cell metabolism gene	RPL36	PGLS	0.825886422	1.77E-138
PRAD	Cell metabolism gene	RPL36	NME2	0.829891245	5.45E-141
PRAD	Cell metabolism gene	RPL36	POLR2F	0.83248798	1.18E-142
PRAD	Cell metabolism gene	RPL36	POLR2I	0.836206321	4.38E-145
PRAD	Cell metabolism gene	RPL36	PSMB7	0.848155165	2.47E-153
PRAD	Cell metabolism gene	RPL36	TIMM13	0.850515493	4.79E-155
PRAD	Cell metabolism gene	RPL36	FAU	0.851959106	4.14E-156
PRAD	Cell metabolism gene	RPL36	SNRPD2	0.860012095	2.98E-162
PRAD	CGC	RPL36	NACA	0.818258566	7.16E-134
PRAD	Epifactor	RPL36	FBL	0.864192021	1.35E-165
PRAD	TF	RPL36	NME2	0.829891245	5.45E-141
PRAD	TF	RPL36	ZNF581	0.835203969	2.01E-144
PRAD	TF	RPL36	ZNF524	0.849475556	2.74E-154
PRAD	TSG	RPL36	GADD45GIP1	0.800289108	7.99E-124
PRAD	TSG	RPL36	GAS5	0.81325832	5.75E-131
PRAD	TSG	RPL36	GNB2L1	0.864054405	1.75E-165
READ	TSG	RPL36	GADD45GIP1	0.81391545	4.91E-26
TGCT	Cell metabolism gene	RPL36	POLR2I	0.80109368	3.75E-36
TGCT	Cell metabolism gene	RPL36	SNRPD2	0.830055747	6.77E-41
THCA	Cell metabolism gene	RPL36	PFDN5	0.800826186	5.13E-129
THCA	Cell metabolism gene	RPL36	POLR2I	0.819622842	5.20E-140
THCA	Cell metabolism gene	RPL36	GPX4	0.83994238	1.94E-153
THCA	Cell metabolism gene	RPL36	FAU	0.851906503	2.93E-162
THCA	Cell metabolism gene	RPL36	SNRPD2	0.877525157	4.42E-184
THCA	Epifactor	RPL36	C17orf49	0.8147221	5.05E-137
THCA	Epifactor	RPL36	TAF10	0.817833849	6.56E-139
THCA	IUPHAR	RPL36	CSNK2B	0.812636979	8.85E-136
THCA	TF	RPL36	ZNF524	0.831404493	1.41E-147
THCA	TSG	RPL36	GNB2L1	0.84424925	1.58E-156
THYM	Cell metabolism gene	RPL36	GUK1	0.802240954	1.18E-28
THYM	Cell metabolism gene	RPL36	TOMM22	0.804488874	6.39E-29
THYM	Cell metabolism gene	RPL36	MMAB	0.806159977	4.03E-29
THYM	Cell metabolism gene	RPL36	ATP5G1	0.80661535	3.55E-29
THYM	Cell metabolism gene	RPL36	PPCDC	0.807777008	2.57E-29
THYM	Cell metabolism gene	RPL36	SSR4	0.808381403	2.17E-29
THYM	Cell metabolism gene	RPL36	PMPCA	0.808788081	1.93E-29
THYM	Cell metabolism gene	RPL36	POLR2J	0.809293372	1.67E-29
THYM	Cell metabolism gene	RPL36	ALG3	0.809880181	1.42E-29
THYM	Cell metabolism gene	RPL36	NANS	0.810801286	1.09E-29
THYM	Cell metabolism gene	RPL36	PSMB7	0.81176998	8.27E-30
THYM	Cell metabolism gene	RPL36	PSME2	0.811965048	7.82E-30
THYM	Cell metabolism gene	RPL36	PSMD4	0.819911101	7.55E-31
THYM	Cell metabolism gene	RPL36	PSMB3	0.822089835	3.90E-31
THYM	Cell metabolism gene	RPL36	GEMIN7	0.822558005	3.38E-31
THYM	Cell metabolism gene	RPL36	MIF	0.823214745	2.76E-31
THYM	Cell metabolism gene	RPL36	ACOT8	0.823485672	2.54E-31
THYM	Cell metabolism gene	RPL36	POLE4	0.825043852	1.57E-31
THYM	Cell metabolism gene	RPL36	TIMM10	0.825949442	1.18E-31
THYM	Cell metabolism gene	RPL36	HMBS	0.826858213	8.89E-32
THYM	Cell metabolism gene	RPL36	IMPDH2	0.827285828	7.77E-32
THYM	Cell metabolism gene	RPL36	GFER	0.827583649	7.07E-32
THYM	Cell metabolism gene	RPL36	PSMC5	0.827680218	6.86E-32
THYM	Cell metabolism gene	RPL36	MPST	0.828682438	4.99E-32
THYM	Cell metabolism gene	RPL36	APRT	0.829244677	4.17E-32
THYM	Cell metabolism gene	RPL36	PTGES2	0.832028617	1.70E-32
THYM	Cell metabolism gene	RPL36	ITPA	0.832101902	1.66E-32
THYM	Cell metabolism gene	RPL36	PHPT1	0.834192089	8.35E-33
THYM	Cell metabolism gene	RPL36	EXOSC5	0.836757645	3.55E-33
THYM	Cell metabolism gene	RPL36	LCMT1	0.837061517	3.21E-33
THYM	Cell metabolism gene	RPL36	GSTP1	0.837831057	2.47E-33
THYM	Cell metabolism gene	RPL36	TIMM8B	0.837966529	2.36E-33
THYM	Cell metabolism gene	RPL36	NME2	0.837996735	2.34E-33
THYM	Cell metabolism gene	RPL36	POLR2H	0.84189065	6.14E-34
THYM	Cell metabolism gene	RPL36	TOMM7	0.847526426	8.30E-35
THYM	Cell metabolism gene	RPL36	MTX1	0.848337431	6.18E-35
THYM	Cell metabolism gene	RPL36	GMPPA	0.854523401	6.17E-36
THYM	Cell metabolism gene	RPL36	POLR2F	0.855516021	4.22E-36
THYM	Cell metabolism gene	RPL36	DPM3	0.856065801	3.41E-36
THYM	Cell metabolism gene	RPL36	SNRPD2	0.856449346	2.94E-36
THYM	Cell metabolism gene	RPL36	SLC27A5	0.858178049	1.50E-36
THYM	Cell metabolism gene	RPL36	TIMM13	0.859458917	9.06E-37
THYM	Cell metabolism gene	RPL36	SSR2	0.859668994	8.34E-37
THYM	Cell metabolism gene	RPL36	TIMM50	0.868091567	2.64E-38
THYM	Cell metabolism gene	RPL36	EXOSC4	0.868394758	2.32E-38
THYM	Cell metabolism gene	RPL36	DPM2	0.86840691	2.31E-38
THYM	Cell metabolism gene	RPL36	PFDN5	0.8853052	1.02E-41
THYM	Cell metabolism gene	RPL36	POLR2I	0.88873357	1.84E-42
THYM	Cell metabolism gene	RPL36	FAU	0.892580309	2.50E-43
THYM	Cell metabolism gene	RPL36	PGLS	0.893797197	1.31E-43
THYM	CGC	RPL36	RBM10	0.804159813	6.99E-29
THYM	CGC	RPL36	MGMT	0.808233787	2.26E-29
THYM	CGC	RPL36	ASPSCR1	0.818161248	1.28E-30
THYM	Epifactor	RPL36	RRP8	0.800790172	1.75E-28
THYM	Epifactor	RPL36	C17orf49	0.802316063	1.16E-28
THYM	Epifactor	RPL36	LAS1L	0.821686295	4.41E-31
THYM	Epifactor	RPL36	ZNHIT1	0.835744927	4.99E-33
THYM	Epifactor	RPL36	EXOSC5	0.836757645	3.55E-33
THYM	Epifactor	RPL36	TAF10	0.838264027	2.14E-33
THYM	Epifactor	RPL36	PRPF31	0.845559913	1.68E-34
THYM	Epifactor	RPL36	BRMS1	0.845885812	1.50E-34
THYM	Epifactor	RPL36	SIRT6	0.860397738	6.24E-37
THYM	Epifactor	RPL36	EXOSC4	0.868394758	2.32E-38
THYM	Epifactor	RPL36	FBL	0.894349893	9.75E-44
THYM	IUPHAR	RPL36	ATP6V0B	0.802690882	1.04E-28
THYM	IUPHAR	RPL36	IMPDH2	0.827285828	7.77E-32
THYM	IUPHAR	RPL36	MPST	0.828682438	4.99E-32
THYM	IUPHAR	RPL36	PTGES2	0.832028617	1.70E-32
THYM	IUPHAR	RPL36	SIRT3	0.846978289	1.01E-34
THYM	IUPHAR	RPL36	SLC27A5	0.858178049	1.50E-36
THYM	IUPHAR	RPL36	SIRT6	0.860397738	6.24E-37
THYM	TF	RPL36	CENPB	0.800058452	2.13E-28
THYM	TF	RPL36	THAP3	0.805627011	4.67E-29
THYM	TF	RPL36	ZBTB48	0.837089919	3.18E-33
THYM	TF	RPL36	NME2	0.837996735	2.34E-33
THYM	TF	RPL36	THAP7	0.840045932	1.16E-33
THYM	TF	RPL36	ZNF787	0.850087499	3.25E-35
THYM	TF	RPL36	ZNF524	0.864346937	1.26E-37
THYM	TF	RPL36	ZNF581	0.913057582	1.44E-48
THYM	TSG	RPL36	GLTSCR2	0.804014236	7.28E-29
THYM	TSG	RPL36	GABARAP	0.817880639	1.39E-30
THYM	TSG	RPL36	GNB2L1	0.831965302	1.73E-32
THYM	TSG	RPL36	ZBTB48	0.837089919	3.18E-33
THYM	TSG	RPL36	GSTP1	0.837831057	2.47E-33
THYM	TSG	RPL36	BRMS1	0.845885812	1.50E-34
THYM	TSG	RPL36	SIRT3	0.846978289	1.01E-34
THYM	TSG	RPL36	STUB1	0.849392052	4.20E-35
THYM	TSG	RPL36	TSSC4	0.855655529	4.00E-36
THYM	TSG	RPL36	SIRT6	0.860397738	6.24E-37
THYM	TSG	RPL36	GADD45GIP1	0.889365276	1.33E-42
UCS	Cell metabolism gene	RPL36	GUK1	0.802240954	1.18E-28
UCS	Cell metabolism gene	RPL36	TOMM22	0.804488874	6.39E-29
UCS	Cell metabolism gene	RPL36	MMAB	0.806159977	4.03E-29
UCS	Cell metabolism gene	RPL36	ATP5G1	0.80661535	3.55E-29
UCS	Cell metabolism gene	RPL36	PPCDC	0.807777008	2.57E-29
UCS	Cell metabolism gene	RPL36	SSR4	0.808381403	2.17E-29
UCS	Cell metabolism gene	RPL36	PMPCA	0.808788081	1.93E-29
UCS	Cell metabolism gene	RPL36	POLR2J	0.809293372	1.67E-29
UCS	Cell metabolism gene	RPL36	ALG3	0.809880181	1.42E-29
UCS	Cell metabolism gene	RPL36	NANS	0.810801286	1.09E-29
UCS	Cell metabolism gene	RPL36	PSMB7	0.81176998	8.27E-30
UCS	Cell metabolism gene	RPL36	PSME2	0.811965048	7.82E-30
UCS	Cell metabolism gene	RPL36	PSMD4	0.819911101	7.55E-31
UCS	Cell metabolism gene	RPL36	PSMB3	0.822089835	3.90E-31
UCS	Cell metabolism gene	RPL36	GEMIN7	0.822558005	3.38E-31
UCS	Cell metabolism gene	RPL36	MIF	0.823214745	2.76E-31
UCS	Cell metabolism gene	RPL36	ACOT8	0.823485672	2.54E-31
UCS	Cell metabolism gene	RPL36	POLE4	0.825043852	1.57E-31
UCS	Cell metabolism gene	RPL36	TIMM10	0.825949442	1.18E-31
UCS	Cell metabolism gene	RPL36	HMBS	0.826858213	8.89E-32
UCS	Cell metabolism gene	RPL36	IMPDH2	0.827285828	7.77E-32
UCS	Cell metabolism gene	RPL36	GFER	0.827583649	7.07E-32
UCS	Cell metabolism gene	RPL36	PSMC5	0.827680218	6.86E-32
UCS	Cell metabolism gene	RPL36	MPST	0.828682438	4.99E-32
UCS	Cell metabolism gene	RPL36	APRT	0.829244677	4.17E-32
UCS	Cell metabolism gene	RPL36	PTGES2	0.832028617	1.70E-32
UCS	Cell metabolism gene	RPL36	ITPA	0.832101902	1.66E-32
UCS	Cell metabolism gene	RPL36	PHPT1	0.834192089	8.35E-33
UCS	Cell metabolism gene	RPL36	EXOSC5	0.836757645	3.55E-33
UCS	Cell metabolism gene	RPL36	LCMT1	0.837061517	3.21E-33
UCS	Cell metabolism gene	RPL36	GSTP1	0.837831057	2.47E-33
UCS	Cell metabolism gene	RPL36	TIMM8B	0.837966529	2.36E-33
UCS	Cell metabolism gene	RPL36	NME2	0.837996735	2.34E-33
UCS	Cell metabolism gene	RPL36	POLR2H	0.84189065	6.14E-34
UCS	Cell metabolism gene	RPL36	TOMM7	0.847526426	8.30E-35
UCS	Cell metabolism gene	RPL36	MTX1	0.848337431	6.18E-35
UCS	Cell metabolism gene	RPL36	GMPPA	0.854523401	6.17E-36
UCS	Cell metabolism gene	RPL36	POLR2F	0.855516021	4.22E-36
UCS	Cell metabolism gene	RPL36	DPM3	0.856065801	3.41E-36
UCS	Cell metabolism gene	RPL36	SNRPD2	0.856449346	2.94E-36
UCS	Cell metabolism gene	RPL36	SLC27A5	0.858178049	1.50E-36
UCS	Cell metabolism gene	RPL36	TIMM13	0.859458917	9.06E-37
UCS	Cell metabolism gene	RPL36	SSR2	0.859668994	8.34E-37
UCS	Cell metabolism gene	RPL36	TIMM50	0.868091567	2.64E-38
UCS	Cell metabolism gene	RPL36	EXOSC4	0.868394758	2.32E-38
UCS	Cell metabolism gene	RPL36	DPM2	0.86840691	2.31E-38
UCS	Cell metabolism gene	RPL36	PFDN5	0.8853052	1.02E-41
UCS	Cell metabolism gene	RPL36	POLR2I	0.88873357	1.84E-42
UCS	Cell metabolism gene	RPL36	FAU	0.892580309	2.50E-43
UCS	Cell metabolism gene	RPL36	PGLS	0.893797197	1.31E-43
UCS	CGC	RPL36	RBM10	0.804159813	6.99E-29
UCS	CGC	RPL36	MGMT	0.808233787	2.26E-29
UCS	CGC	RPL36	ASPSCR1	0.818161248	1.28E-30
UCS	Epifactor	RPL36	RRP8	0.800790172	1.75E-28
UCS	Epifactor	RPL36	C17orf49	0.802316063	1.16E-28
UCS	Epifactor	RPL36	LAS1L	0.821686295	4.41E-31
UCS	Epifactor	RPL36	ZNHIT1	0.835744927	4.99E-33
UCS	Epifactor	RPL36	EXOSC5	0.836757645	3.55E-33
UCS	Epifactor	RPL36	TAF10	0.838264027	2.14E-33
UCS	Epifactor	RPL36	PRPF31	0.845559913	1.68E-34
UCS	Epifactor	RPL36	BRMS1	0.845885812	1.50E-34
UCS	Epifactor	RPL36	SIRT6	0.860397738	6.24E-37
UCS	Epifactor	RPL36	EXOSC4	0.868394758	2.32E-38
UCS	Epifactor	RPL36	FBL	0.894349893	9.75E-44
UCS	IUPHAR	RPL36	ATP6V0B	0.802690882	1.04E-28
UCS	IUPHAR	RPL36	IMPDH2	0.827285828	7.77E-32
UCS	IUPHAR	RPL36	MPST	0.828682438	4.99E-32
UCS	IUPHAR	RPL36	PTGES2	0.832028617	1.70E-32
UCS	IUPHAR	RPL36	SIRT3	0.846978289	1.01E-34
UCS	IUPHAR	RPL36	SLC27A5	0.858178049	1.50E-36
UCS	IUPHAR	RPL36	SIRT6	0.860397738	6.24E-37
UCS	TF	RPL36	CENPB	0.800058452	2.13E-28
UCS	TF	RPL36	THAP3	0.805627011	4.67E-29
UCS	TF	RPL36	ZBTB48	0.837089919	3.18E-33
UCS	TF	RPL36	NME2	0.837996735	2.34E-33
UCS	TF	RPL36	THAP7	0.840045932	1.16E-33
UCS	TF	RPL36	ZNF787	0.850087499	3.25E-35
UCS	TF	RPL36	ZNF524	0.864346937	1.26E-37
UCS	TF	RPL36	ZNF581	0.913057582	1.44E-48
UCS	TSG	RPL36	GLTSCR2	0.804014236	7.28E-29
UCS	TSG	RPL36	GABARAP	0.817880639	1.39E-30
UCS	TSG	RPL36	GNB2L1	0.831965302	1.73E-32
UCS	TSG	RPL36	ZBTB48	0.837089919	3.18E-33
UCS	TSG	RPL36	GSTP1	0.837831057	2.47E-33
UCS	TSG	RPL36	BRMS1	0.845885812	1.50E-34
UCS	TSG	RPL36	SIRT3	0.846978289	1.01E-34
UCS	TSG	RPL36	STUB1	0.849392052	4.20E-35
UCS	TSG	RPL36	TSSC4	0.855655529	4.00E-36
UCS	TSG	RPL36	SIRT6	0.860397738	6.24E-37
UCS	TSG	RPL36	GADD45GIP1	0.889365276	1.33E-42
UVM	Cell metabolism gene	RPL36	MPST	0.80017052	5.39E-19
UVM	Cell metabolism gene	RPL36	TOMM22	0.820014546	1.37E-20
UVM	Cell metabolism gene	RPL36	SSR2	0.861074474	1.28E-24
UVM	Cell metabolism gene	RPL36	FAU	0.897072194	2.16E-29
UVM	Epifactor	RPL36	TRIM28	0.823565185	6.74E-21
UVM	Epifactor	RPL36	FBL	0.901078187	4.96E-30
UVM	IUPHAR	RPL36	MPST	0.80017052	5.39E-19
UVM	IUPHAR	RPL36	TRIM28	0.823565185	6.74E-21
UVM	Kinase	RPL36	TRIM28	0.823565185	6.74E-21
UVM	TF	RPL36	ZNF581	0.873379979	4.38E-26
UVM	TSG	RPL36	GLTSCR2	0.869358759	1.37E-25
UVM	TSG	RPL36	GNB2L1	0.896148692	3.01E-29

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Protein structure

Protein 3D structure
Visit iCn3D.

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Protein-Protein Interaction

Protein-protein interaction networks
* Overlap between up-regulated DEGs (log2FC<-1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

Overlap between down-regulated DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

* Edge colors based on TCGA cancer types.

* Overlap between DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network per cancer (center: Translation factor, node: DEGs, node color: log2FC, edges: weighted by -log2(adj.P))

Cancer type	Translation factor	Interacting protein coding gene	FC	adj.pval
KIRP	RPL36	RPL18A	-1.51651392808885	0.00016188295558095
KICH	RPL36	RPS27A	1.75396693785956	0.000187873840332031
KIRP	RPL36	RPS16	-1.35957043617517	0.00019507110118866
COAD	RPL36	RPS3	1.48730375143014	0.000411599874496461
KIRP	RPL36	RPS11	-1.01861570565103	0.00105937570333481
LIHC	RPL36	RPL8	-4.84588284974558	0.00110314154326131
PRAD	RPL36	RPL18A	1.40600175748499	0.00205137828390396
KICH	RPL36	RPL19	1.36901182894089	0.00250792503356934
KICH	RPL36	RPS12	1.26997381758431	0.00308787822723389
LUAD	RPL36	RPL19	-1.31398026615725	0.00993159558412698
THCA	RPL36	RPS16	-6.16322798156577	0.0115764821363307
BLCA	RPL36	RPS12	-1.47804673440421	0.0204124450683594
BLCA	RPL36	RPS27A	-1.04747470069188	0.0258216857910156
HNSC	RPL36	RPS3	-4.73505819095135	0.0273726439852453
COAD	RPL36	RPS11	1.35307548998204	0.0312207043170929
LUSC	RPL36	RPL19	-2.14669889516666	0.044366810398747
KIRC	RPL36	RPL19	-2.73485271276676	1.33980982873695e-10
BRCA	RPL36	RPS12	-4.91239327478244	1.85340619742495e-09
KIRP	RPL36	RPL37	-1.17421621947139	2.26888805627823e-05
KIRC	RPL36	RPL35	-1.06475238059392	2.72286325678163e-08
KIRC	RPL36	RPL8	-1.18252459971773	5.64962994208288e-07
KIRP	RPL36	RPL8	-1.53003692350119	6.0301274061203e-05
KIRC	RPL36	RPS16	-1.66149869889384	7.8509870430991e-09
BRCA	RPL36	RPS27A	-4.28512148200424	7.8788217967112e-14
KIRC	RPL36	RPL37	-2.87198822058464	8.03913394748564e-12
KIRP	RPL36	RPL35	-1.52981101975496	9.0546440333128e-05
KIRC	RPL36	RPS3	-1.29560847926387	9.05905681935088e-10
KIRC	RPL36	RPL18A	-4.43079304960843	9.2516163152192e-11

Protein-protein interactors with this translation factor (BIOGRID-3.4.160)

PPI interactors with RPL36

MAGEB2, PSTPIP1, CNBP, PRKRA, RPL18A, ARRB2, CUL3, CUL2, CDK2, CUL1, CAND1, APP, RPL18, RPL4, RPL30, RPL11, RPL35, RPL5, RPL19, RPL6, RPS8, RPL3, RPL14, RPL7A, RPS4X, RPL21, RPS25, RPL7, RPS16, RPS6, RPL23A, RPS28, RPS15, RPS24, RPL13, RPL27A, RPL8, RPL38, HNRNPDL, DDX42, DHX15, PTBP1, C19orf43, NONO, ESR1, FN1, VCAM1, UBL4A, ITGA4, PAN2, IGSF8, ICAM1, AIMP1, KARS, QARS, RPL17, DARS, EEF1E1, RPL15, RPL26, RPLP0, CUL7, RNF2, ABCE1, EIF6, HSD17B12, RNPS1, RPL10A, RPL12, RPL13A, RPL27, RPL28, DDX18, GTPBP4, RPL10, RPL10L, RPL22, RPL23, RPL24, RPL26L1, RPL31, RPL34, RPL35A, RPS10, RPS12, RPS13, RPS19, RPS3, RPL37A, RPL3L, RPL9, RPLP1, RPLP2, RPS11, RPS14, RPS15A, RPS18, RPS2, RPS20, RPS23, LOC101929876, RPS26, RPS3A, RPS5, RPS7, RPS9, RPSA, UBA52, WDR12, HIST1H3E, EZH2, HNRNPU, NPM1, NOP56, MPHOSPH8, EXOSC5, Rpl35, Srp72, Rrbp1, Bag2, Brwd3, ZNF746, CDC14B, DUSP13, DUSP5, ZC3HAV1, KNOP1, KIAA0020, MECP2, PES1, GPATCH4, PRDM5, NCL, CYLD, COX15, VDAC1, TRIM25, BRCA1, CFTR, API5, BMP4, MATN2, PCBP1, PYHIN1, PRPF8, AAR2, PIH1D1, EFTUD2, RNF4, CHD3, LARP7, SPDL1, RIOK1, ESR2, HEXIM1, MEPCE, AGR2, RECQL4, DCPS, MYC, AURKAIP1, METTL14, RC3H1, RC3H2, ATG16L1, PHB, RBX1, USP14, PPP1CC, VRK1, HIST1H4A, P2RY6, SNRNP70, ITFG1, HMGB1, N, BIRC3, STAU1, NFX1, WWP2, Dnajc17, CMTR1, ARIH2, PLEKHA4, YAP1, TFCP2, FANCD2, PTEN, ZC3H18, MAP3K14, PTPN6, MUC12, AASDH, FTSJ3, ZFC3H1, SNIP1, ORF10, ORF8, DUX4, CIT, ANLN, AURKB, CHMP4B, CHMP4C, ECT2, KIF14, KIF20A, KIF23, PRC1, GRSF1, MRRF, FASN, INS, Apc2, RBM39, FBP1, RIN3, DNAJC15, DNAJC1, DNAJC2, DNAJC9, SETD8, CBX6, HIST1H2AI, PABPC1, RALY, S100A7, SETD4, CBX1, S100A8, H1FX, DAW1, HNRNPA2B1, S100A9, CBX8, RPL29, HNRNPC, DDX58, UFL1, DDRGK1, TRIM37, USP15, FZR1, PAGE4, MAP4K2, MAP4K3, MAP4K4, MINK1, NUDCD2, CCDC106, ABT1, PAK1IP1, RSL24D1, ZNF845, DDX50, GNL2, H2AFX, PAPD5, ZNF184, DDX10, ZKSCAN8, POP1, DDX21, RPL7L1, PATZ1, NSA2, ZBTB24, IMP4, TRIM56, ZFP62, RRS1, ZNF770, MYBBP1A, GTPBP10, NOP2, SRP68, DDX24, SRSF5, ZNF70, SCAF1, GLE1, SRRM1, TAF1D, ZSCAN25, TRMT1L, NMNAT1, SCAF4, DKC1, ZC3H10, RRP15, ZNF48, ZCCHC7, HERC5, EBNA1BP2, CENPI, DDX54, ZNF689, ZNF791, TFB1M, TEX10, SREK1, NTN1, ZNF629, CENPQ, CCDC137, ZNF777, PRPF4B, RPF2, NKTR, BEND7, SRSF1, ZBTB41, ZNF445, GLTSCR2, WHSC1, RBM28, BMS1, NSD1, CCDC140, SPATS2L, PWP2, PDCD11, TOPORS, PPAN-P2RY11, CENPU, RRP1B, RPF1, ZNF646, BUD13, MOV10, ZNF768, YTHDC2, CEBPZ, ZNF624, AKAP17A, NOL8, ZNF16, ZNF708, SPTY2D1, ZNF668, REXO4, GZF1, CENPT, URB2, BOP1, NSUN4, STAU2, GLYR1, FLT1, SDAD1, DDX55, ZNF317, NIP7, CENPC, CDK12, ZCCHC6, DHX8, ZNF397, MYEF2, HP1BP3, RSL1D1, NOC2L, TSPYL2, ZNF354A, RRP8, URB1, RSBN1, MPHOSPH10, SURF6, NOL10, ZNF22, MINA, C7orf50, DDX31, ZNF512, DDX51, KMT2A, CENPN, DNTTIP2, RPL36AL, RPL32, ZNF107, RBM34, BRIX1, SRP72, SRPK1, DHX30, NVL, NOC3L, TAF1C, TAF1B, TAF1A, DDX27, TTF1, ZNF616, ZNF483, BTF3, FSCN1, FBXW7, NLRP7, RCHY1, PER2, KLF15, KLF16, KLF8, BRD4, BRDT,

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Mutations

Clinically associated variants from ClinVar.

Gene

Chr

Position

RefSeq

VarSeq

RefSeeq

VarType

Pathogenic

Disease

VarInfo

nsSNVs with sample frequency (size of circle) from TCGA 33 cancers.

SNVs and Indels

Gene	Cancer type	Chromosome	Start	End	RefSeeq	MutSeq	Mutation type	AAchange	# samples
RPL36	ESCA	chr19	5691411	5691411	G	T	Nonsense_Mutation	p.E59*	4
RPL36	BRCA	chr19	5691557	5691557	C	G	Missense_Mutation	p.I81M	4
RPL36	HNSC	chr19	5691333	5691333	C	G	Missense_Mutation	p.L33V	3
RPL36	HNSC	chr19	5691434	5691434	C	A	Missense_Mutation	p.D66E	2
RPL36	ESCA	chr19	5691620	5691620	C	G	Silent		2
RPL36	ESCA	chr19	5691620	5691620	C	G	Silent	p.A102A	2
RPL36	BLCA	chr19	5691448	5691448	A	C	Missense_Mutation	p.K71T	2
RPL36	ESCA	chr19	5691411	5691411	G	T	Missense_Mutation		2
RPL36	SARC	chr19	5691405	5691405	G	C	Missense_Mutation		2
RPL36	SARC	chr19	5691405	5691405	G	C	Missense_Mutation	p.A57P	2
RPL36	STAD	chr19	5691598	5691598	C	T	Missense_Mutation	p.A95V	1
RPL36	CESC	chr19	5691504	5691504	G	T	Nonsense_Mutation	p.E90*	1
RPL36	THYM	chr19	5685085	5685085	C	T	Silent		1
RPL36	CESC	chr19	5691566	5691566	G	A	Silent	p.K84	1
RPL36	LGG	chr19	5691425	5691425	C	T	Silent	p.V63V	1
RPL36	UVM	chr19	5691489	5691489	G	T	Missense_Mutation		1
RPL36	LGG	chr19	5691360	5691360	G	A	Missense_Mutation	p.D42N	1
RPL36	ESCA	chr19	5691620	5691620	C	G	Silent	p.A102	1
RPL36	LGG	chr19	5691360	5691360	G	A	Missense_Mutation		1
RPL36	BLCA	chr19	5691448	5691448	A	C	Missense_Mutation		1
RPL36	LIHC	chr19	5691422	5691422	G	-	Frame_Shift_Del	p.K62fs	1
RPL36	BLCA	chr19	5691353	5691353	C	T	Silent		1
RPL36	ESCA	chr19	5691411	5691411	G	T	Nonsense_Mutation	p.E59X	1
RPL36	PAAD	chr19	5691599	5691599	C	T	Silent	p.A95A	1
RPL36	BLCA	chr19	5691485	5691485	G	A	Silent		1
RPL36	PAAD	chr19	5691442	5691442	C	T	Missense_Mutation	p.A69V	1
RPL36	SARC	chr19	5691490	5691490	G	T	Missense_Mutation		1
RPL36	BLCA	chr19	5691353	5691353	C	T	Silent	p.F39F	1
RPL36	HNSC	chr19	5691434	5691434	C	A	Missense_Mutation		1
RPL36	HNSC	chr19	5691333	5691333	C	G	Missense_Mutation		1
RPL36	CESC	chr19	5691566	5691566	G	A	Silent		1

Copy number variation (CNV) of RPL36
* Click on the image to open the original image in a new window.

Fusion gene breakpoints (product of the structural variants (SVs)) across RPL36
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion genes with this translation factor from FusionGDB2.0.

FusionGDB2 ID	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
101054	CESC	TCGA-EK-A2RJ	ADAMTSL4	chr1	150529811	+	RPL36	chr19	5691329	+
101054	BRCA	TCGA-BH-A1FE-01A	CHAF1A	chr19	4439504	+	RPL36	chr19	5690610	-
101054	N/A	BG231145	CTC-329D1.2	chr5	139773440	-	RPL36	chr19	5691678	-
101054	N/A	AA552195	FAM65B	chr6	24811905	+	RPL36	chr19	5691678	-
101054	UCEC	TCGA-DF-A2KZ-01A	FOXP2	chr7	113937158	-	RPL36	chr19	5691541	+
101054	N/A	BM015665	HMGA1	chr6	34213557	+	RPL36	chr19	5691640	+
101054	N/A	EC577108	LRCH2	chrX	114433327	-	RPL36	chr19	5691678	-
101054	BRCA	TCGA-C8-A12L-01A	MFSD12	chr19	3547270	-	RPL36	chr19	5690042	+
101054	N/A	BG231063	PDE7A	chr8	66724444	-	RPL36	chr19	5691678	-
76642	OV	TCGA-24-1435	RPL36	chr19	5691464	+	ALG3	chr3	183966759	-
76642	N/A	EC443172	RPL36	chr19	5691636	-	ATP5I	chr4	667175	-
78324	N/A	DD229299	RPL36	chr19	5691637	-	C2orf48	chr2	10338955	+
91103	READ	TCGA-AG-A008	RPL36	chr19	5691595	+	CYBA	chr16	88709927	-
99204	OV	TCGA-61-1743	RPL36	chr19	5690611	+	GAB2	chr11	77936248	-
87555	N/A	AI497618	RPL36	chr19	5691635	-	IGFBP5	chr2	217541449	+
103141	N/A	BP430734	RPL36	chr19	5691678	+	KTN1	chr14	56061235	-
79027	N/A	BM015824	RPL36	chr19	5691464	+	LONP1	chr19	5691543	+
76642	N/A	EC553345	RPL36	chr19	5690356	+	LTBP3	chr11	65306586	-
76642	BRCA	TCGA-C8-A12L-01A	RPL36	chr19	5690338	+	MFSD12	chr19	3544937	-
76642	OV	TCGA-13-1497	RPL36	chr19	5691464	+	MSLN	chr16	817375	+
95663	N/A	BI862490	RPL36	chr19	5691678	+	PPP6R2	chr22	50793679	-
83565	GBM	TCGA-27-2523-01A	RPL36	chr19	5690338	+	RANBP3	chr19	5928098	-
76642	N/A	BI856291	RPL36	chr19	5691678	+	RRP1B	chr21	45099149	-
100454	N/A	AI497603	RPL36	chr19	5691636	-	SLC23A2	chr20	4833667	+
100464	N/A	AI547077	RPL36	chr19	5691678	+	SLC24A2	chr9	19588189	-
101879	N/A	AA578143	RPL36	chr19	5691678	+	THSD7B	chr2	138330270	+
85743	N/A	EC533603	RPL36	chr19	5691678	+	TPCN1	chr12	113699240	-
95194	N/A	BG231242	RPL36	chr19	5691678	+	TTLL5	chr14	76143132	-
76642	GBM	TCGA-06-5415	RPL36	chr19	5690611	+	TTYH1	chr19	54946721	+
76642	GBM	TCGA-06-5415-01A	RPL36	chr19	5690611	+	TTYH1	chr19	54946722	+
101054	N/A	BE881501	UGGT1	chr2	128947822	+	RPL36	chr19	5691635	+
101055	N/A	BG271954	ZFP36L2	chr2	43451353	+	RPL36	chr19	5691411	-

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Prognostic Analysis

Kaplan-Meier plots with logrank tests of overall survival (OS)

Cancer type	Translation factor	Coefficent	Hazard ratio	Wald test pval	Likelihool ratio pval	Logrank test pval	# samples
SARC	RPL36	1.45658236106572	0.376092843065936	0.0011860066272683	0.00107527687359002	0.00127713122550061	265
PRAD	RPL36	2.4170200703532	0.882535405515251	0.0147699243644786	0.00445019593258095	0.00849357815840957	549
PRAD	RPL36	2.4170200703532	0.882535405515251	0.0147699243644786	0.00445019593258095	0.00849357815840957	549
BLCA	RPL36	0.865265267080846	-0.144719151917529	0.0232533081024706	0.0239715354427255	0.023036593279356	422
KIRC	RPL36	1.28222927577321	0.248600184764906	1.24497131653444e-05	9.3337773828729e-06	1.12368821547886e-05	604
KIRC	RPL36	1.28222927577321	0.248600184764906	1.24497131653444e-05	9.3337773828729e-06	1.12368821547886e-05	604

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Translation factor and Gender

Differential gene expression between female and male. (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
KIRC	RPL36	0.0121788251056638	0.34
SARC	RPL36	0.0203260314184145	0.55
MESO	RPL36	0.0479744281151289	1

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Translation factor and Age

Differential gene expression between young and old age groups (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
LUSC	RPL36	0.00487936403844555	0.16
PAAD	RPL36	0.0119960441254012	0.38

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Related Drugs

Drugs targeting genes involved in this translation factor.
(DrugBank Version 5.1.8 2021-05-08)

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases

Diseases associated with this translation factor.
(DisGeNet 4.0)

Disease ID	Disease Name	# PubMeds	Disease source
C1260899	Anemia, Diamond-Blackfan	1	GENOMICS_ENGLAND