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	Gene Summary
	Translation studies in PubMed
	Exon Skipping Events
	Expression
	Expression Regulation
	Associated Genes
	Protein 3D Structure
	Protein-Protein Interaction
	Mutations
	Prognostic Analysis
	Gender Association
	Age Association
	Related Drugs
	Related Diseases

Translation Factor: PRKDC (NCBI Gene ID:5591)

Gene Summary

Gene Summary

Gene Information	Gene Name: PRKDC
	Gene ID: 5591
	Gene Symbol	PRKDC
	Gene ID	5591
	Gene Name	protein kinase, DNA-activated, catalytic subunit
	Synonyms	DNA-PKC\|DNA-PKcs\|DNAPK\|DNAPKc\|DNPK1\|HYRC\|HYRC1\|IMD26\|XRCC7\|p350
	Cytomap	8q11.21
	Type of Gene	protein-coding
	Description	DNA-dependent protein kinase catalytic subunitDNA-PK catalytic subunithyper-radiosensitivity of murine scid mutation, complementing 1p460protein kinase, DNA-activated, catalytic polypeptide
	Modification date	20200322
	UniProtAcc	P78527

Child GO biological process term(s) under GO:0006412

GO ID	GO term
GO:0006417	Regulation of translation
GO:0045727	Positive regulation of translation
GO:0006412	Translation

Gene ontology of translaction factor with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	PRKDC	GO:0002218	activation of innate immune response	28712728
Hgene	PRKDC	GO:0006468	protein phosphorylation	26237645
Hgene	PRKDC	GO:0006974	cellular response to DNA damage stimulus	26237645
Hgene	PRKDC	GO:0018105	peptidyl-serine phosphorylation	15194694\|19303849
Hgene	PRKDC	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining	26237645

Inferred gene age of translation factor.

Gene	Inferred gene age group among (0 - 67.6], (67.6 - 355.7], (355.7 - 733], (733 - 1119.25], >1119.25
PRKDC	(733 - 1119.25]

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Translation Studies in PubMed

We searched PubMed using 'PRKDC[title] AND translation [title] AND human.'

Gene	Title	PMID
PRKDC	.	.

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Exon Skipping Events

Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
For more annotations, please visit our ExonSkipDB.

Open reading frame (ORF) analsis of exon skipping events based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ENST	Exon skip start (DNA)	Exon Skip end (DNA)	ORF
ENST00000314191	48689404	48689544	Frame-shift
ENST00000314191	48690246	48690435	In-frame
ENST00000314191	48694722	48694815	In-frame
ENST00000314191	48696302	48696370	Frame-shift
ENST00000314191	48706850	48707062	Frame-shift
ENST00000314191	48711770	48711951	Frame-shift
ENST00000314191	48739216	48739422	Frame-shift
ENST00000314191	48767782	48767934	Frame-shift
ENST00000314191	48777116	48777324	Frame-shift
ENST00000314191	48798504	48798708	In-frame
ENST00000314191	48800107	48800266	In-frame
ENST00000314191	48809720	48809854	Frame-shift
ENST00000314191	48811029	48811129	Frame-shift
ENST00000314191	48817428	48817536	In-frame
ENST00000314191	48830836	48830943	Frame-shift
ENST00000314191	48845579	48845732	In-frame
ENST00000314191	48848291	48848460	Frame-shift
ENST00000314191	48868433	48868508	In-frame

Exon skipping position in the amino acid sequence.

ENST	Exon skip start (DNA)	Exon Skip end (DNA)	Len(transcript seq)	Exon skip start (mRNA)	Exon Skip end (mRNA)	Len(amino acid seq)	Exon skip start (AA)	Exon Skip end (AA)
ENST00000314191	48690246	48690435	13523	11908	12096	4128	3950	4013
ENST00000314191	48694722	48694815	13523	11451	11543	4128	3798	3828
ENST00000314191	48798504	48798708	13523	4627	4830	4128	1523	1591
ENST00000314191	48800107	48800266	13523	4468	4626	4128	1470	1523
ENST00000314191	48817428	48817536	13523	2992	3099	4128	978	1014
ENST00000314191	48845579	48845732	13523	1681	1833	4128	541	592
ENST00000314191	48868433	48868508	13523	382	456	4128	108	133

Potentially (partially) lost protein functional features of UniProt.

UniProtAcc

Exon skip start (AA)

Exon Skip end (AA)

Function feature start (AA)

Function feature end (AA)

Functional feature type

Functional feature desc.

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Expression

Gene expression level across TCGA pancancer

Gene expression level across GTEx pantissue

Expression level of gene isoforms across TCGA pancancer

Expression level of gene isoforms across GTEx pantissue

Cancer(tissue) type-specific expression level of Translation factor using z-score distriution

Differential expression between tumor and matched normal (in the cancer types with more than 10 matched samples)

Cancer type	Translation factor	FC	adj.pval
KIRC	PRKDC	1.00477849807903	0.000438553382338663
CHOL	PRKDC	-2.76390227240629	0.00390625
PRAD	PRKDC	-1.20416899184154	0.00860539174499754

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Expression Regulation

Translation factor expression regulation through miRNA binding

Cancer type

Gene

miRNA

TargetScan binding score (Context++ score percentile)

Coefficient

Pvalue

Translation factor expression regulation through methylation in the promoter of Translation factor

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through methylation in the gene body of Translation factor (positive regulation)

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through copy number variation of Translation factor

Cancer type	Gene	Coefficient	Pvalue
OV	PRKDC	0.09335789	0.003345841
UVM	PRKDC	-0.196677762	0.01935776
STAD	PRKDC	0.097052325	0.048981516

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Associated Genes

Strongly correlated genes belong to cellular important gene groups with PRKDC (coefficient>0.8, pval<0.05, node color based on FC between tumor and matched normal). Significantly associated important genes in the individual cancer types. * Cell metabolism gene: cell metabolism genes from REACTOME (black edge), IUPHAR: drug target genes from IUPHAR (blue edge), Kinase: human kinase genes (brown edge), CGC: cancer gene census genes (orange edge), TSG: tumor suppresor genes (purple edge), Epifactor: epigenetic factors (light blue edge), TF: transcription factors (green)

Cancer type	Gene group	Translation factor	Correlated gene	Coefficient	Pvalue
CHOL	Cell metabolism gene	PRKDC	NCOA6	0.80690256	2.18E-11
CHOL	CGC	PRKDC	RAD21	0.801878285	3.59E-11
CHOL	CGC	PRKDC	MSI2	0.802369905	3.42E-11
CHOL	CGC	PRKDC	FUBP1	0.80294396	3.24E-11
CHOL	Epifactor	PRKDC	NCOA6	0.80690256	2.18E-11
CHOL	Epifactor	PRKDC	HUWE1	0.812431992	1.24E-11
CHOL	TSG	PRKDC	ANAPC1	0.807753808	2.00E-11
DLBC	Cell metabolism gene	PRKDC	TNPO1	0.806291604	4.65E-12
DLBC	Cell metabolism gene	PRKDC	NUP153	0.806852593	4.38E-12
DLBC	Cell metabolism gene	PRKDC	MED1	0.816236542	1.55E-12
DLBC	Cell metabolism gene	PRKDC	POLR3A	0.817873884	1.29E-12
DLBC	Cell metabolism gene	PRKDC	POLR2B	0.850834215	1.90E-14
DLBC	CGC	PRKDC	RFWD3	0.813846196	2.03E-12
DLBC	CGC	PRKDC	FUBP1	0.816699274	1.47E-12
DLBC	CGC	PRKDC	SUZ12	0.822298774	7.69E-13
DLBC	CGC	PRKDC	BARD1	0.834718834	1.68E-13
DLBC	Epifactor	PRKDC	DDX21	0.800667146	8.42E-12
DLBC	Epifactor	PRKDC	TAF2	0.80552777	5.05E-12
DLBC	Epifactor	PRKDC	USP49	0.80639349	4.60E-12
DLBC	Epifactor	PRKDC	SMARCA5	0.819672755	1.05E-12
DLBC	Epifactor	PRKDC	SUZ12	0.822298774	7.69E-13
DLBC	Epifactor	PRKDC	BARD1	0.834718834	1.68E-13
DLBC	TF	PRKDC	E2F8	0.805643189	4.98E-12
DLBC	TSG	PRKDC	RBL1	0.821918578	8.04E-13
DLBC	TSG	PRKDC	SUZ12	0.822298774	7.69E-13
DLBC	TSG	PRKDC	BARD1	0.834718834	1.68E-13
DLBC	TSG	PRKDC	ANAPC1	0.864924215	2.27E-15
KICH	CGC	PRKDC	UBR5	0.830318446	2.55E-24
KICH	Epifactor	PRKDC	UBR5	0.830318446	2.55E-24
KICH	IUPHAR	PRKDC	TNKS	0.810596074	2.15E-22
KIRP	Cell metabolism gene	PRKDC	NUP155	0.868220955	1.02E-99
KIRP	CGC	PRKDC	ASXL2	0.813625895	1.35E-77
KIRP	Epifactor	PRKDC	HUWE1	0.803879323	2.06E-74
KIRP	Epifactor	PRKDC	ASXL2	0.813625895	1.35E-77
KIRP	IUPHAR	PRKDC	IDE	0.802605278	5.21E-74
KIRP	IUPHAR	PRKDC	SLC30A6	0.813387765	1.63E-77
KIRP	TF	PRKDC	ATF6	0.835782366	1.39E-85
LAML	Cell metabolism gene	PRKDC	POLA1	0.828676152	5.88E-45
LAML	Cell metabolism gene	PRKDC	NUP155	0.837801712	8.26E-47
LAML	TSG	PRKDC	ANAPC1	0.840144414	2.65E-47
LGG	Cell metabolism gene	PRKDC	NUP155	0.834383761	1.06E-138
LGG	CGC	PRKDC	WRN	0.826510473	7.23E-134
LGG	TSG	PRKDC	RBL1	0.806151506	2.03E-122
PAAD	Cell metabolism gene	PRKDC	NUP155	0.823348694	2.13E-46
PCPG	Cell metabolism gene	PRKDC	PAFAH1B2	0.800736137	4.89E-43
PCPG	Cell metabolism gene	PRKDC	LONP2	0.801983032	2.91E-43
PCPG	Cell metabolism gene	PRKDC	GSR	0.818060682	2.58E-46
PCPG	Cell metabolism gene	PRKDC	PRKAR2A	0.82765283	2.76E-48
PCPG	Cell metabolism gene	PRKDC	NCOA2	0.83186232	3.45E-49
PCPG	Cell metabolism gene	PRKDC	NUP155	0.839083218	8.50E-51
PCPG	CGC	PRKDC	PAFAH1B2	0.800736137	4.89E-43
PCPG	CGC	PRKDC	IL6ST	0.803994568	1.25E-43
PCPG	CGC	PRKDC	STRN	0.812048594	3.86E-45
PCPG	CGC	PRKDC	TRIP11	0.822051265	4.04E-47
PCPG	CGC	PRKDC	ASXL2	0.828212986	2.10E-48
PCPG	CGC	PRKDC	NCOA2	0.83186232	3.45E-49
PCPG	Epifactor	PRKDC	ASXL2	0.828212986	2.10E-48
PCPG	Epifactor	PRKDC	NCOA2	0.83186232	3.45E-49
PCPG	IUPHAR	PRKDC	ADAM10	0.802085629	2.79E-43
PCPG	IUPHAR	PRKDC	IL6ST	0.803994568	1.25E-43
PCPG	IUPHAR	PRKDC	LNPEP	0.804394184	1.06E-43
PCPG	IUPHAR	PRKDC	SAMD8	0.809402863	1.23E-44
PCPG	IUPHAR	PRKDC	GSR	0.818060682	2.58E-46
PCPG	IUPHAR	PRKDC	DPP8	0.818480239	2.12E-46
PCPG	IUPHAR	PRKDC	PRKAR2A	0.82765283	2.76E-48
PCPG	IUPHAR	PRKDC	NCOA2	0.83186232	3.45E-49
PCPG	IUPHAR	PRKDC	SLC30A4	0.833085939	1.87E-49
PCPG	IUPHAR	PRKDC	SLC30A6	0.83553646	5.36E-50
PCPG	IUPHAR	PRKDC	LMTK2	0.837437116	2.01E-50
PCPG	Kinase	PRKDC	LMTK2	0.837437116	2.01E-50
PCPG	TF	PRKDC	ZKSCAN1	0.803258832	1.71E-43
PCPG	TF	PRKDC	ATF6	0.808076578	2.19E-44
PCPG	TF	PRKDC	NCOA2	0.83186232	3.45E-49
PCPG	TSG	PRKDC	ANAPC1	0.814409741	1.35E-45
PRAD	CGC	PRKDC	UBR5	0.80543216	1.36E-126
PRAD	Epifactor	PRKDC	UBR5	0.80543216	1.36E-126
TGCT	Cell metabolism gene	PRKDC	NUP153	0.823319449	1.02E-39
TGCT	CGC	PRKDC	N4BP2	0.833639201	1.52E-41
TGCT	Epifactor	PRKDC	GTF3C4	0.803999361	1.36E-36
TGCT	Epifactor	PRKDC	HCFC1	0.833046214	1.95E-41
TGCT	IUPHAR	PRKDC	GTF3C4	0.803999361	1.36E-36
THCA	Cell metabolism gene	PRKDC	PDP2	0.803368798	1.97E-130
THCA	Cell metabolism gene	PRKDC	POLR3A	0.803413461	1.86E-130
THCA	Cell metabolism gene	PRKDC	GNA11	0.80827341	3.17E-133
THCA	Cell metabolism gene	PRKDC	GART	0.812106212	1.82E-135
THCA	Cell metabolism gene	PRKDC	UGCG	0.817175464	1.66E-138
THCA	Cell metabolism gene	PRKDC	CLOCK	0.821695749	2.66E-141
THCA	Cell metabolism gene	PRKDC	MAN2A1	0.823551489	1.80E-142
THCA	Cell metabolism gene	PRKDC	SEC24B	0.826915113	1.26E-144
THCA	Cell metabolism gene	PRKDC	PHAX	0.829634158	2.10E-146
THCA	Cell metabolism gene	PRKDC	MAN1A2	0.832527476	2.49E-148
THCA	Cell metabolism gene	PRKDC	NCOA2	0.843962816	2.55E-156
THCA	Cell metabolism gene	PRKDC	IPMK	0.844540059	9.69E-157
THCA	Cell metabolism gene	PRKDC	SPTLC2	0.849170057	3.56E-160
THCA	Cell metabolism gene	PRKDC	PIK3CA	0.858778205	1.10E-167
THCA	Cell metabolism gene	PRKDC	MGAT5	0.862536414	8.94E-171
THCA	Cell metabolism gene	PRKDC	PRKAR2A	0.870392347	1.53E-177
THCA	Cell metabolism gene	PRKDC	XRN2	0.87522333	6.30E-182
THCA	Cell metabolism gene	PRKDC	MED1	0.879439909	6.61E-186
THCA	Cell metabolism gene	PRKDC	PAFAH1B2	0.886000015	2.11E-192
THCA	Cell metabolism gene	PRKDC	NUP155	0.899739165	2.09E-207
THCA	CGC	PRKDC	NBN	0.806037977	6.07E-132
THCA	CGC	PRKDC	GNA11	0.80827341	3.17E-133
THCA	CGC	PRKDC	WRN	0.80974339	4.44E-134
THCA	CGC	PRKDC	PTPN11	0.810686287	1.25E-134
THCA	CGC	PRKDC	CLTC	0.819919318	3.41E-140
THCA	CGC	PRKDC	CDK12	0.82434491	5.64E-143
THCA	CGC	PRKDC	PBRM1	0.824404859	5.16E-143
THCA	CGC	PRKDC	KDM5A	0.841846563	8.57E-155
THCA	CGC	PRKDC	AFF4	0.842072164	5.91E-155
THCA	CGC	PRKDC	NCOA2	0.843962816	2.55E-156
THCA	CGC	PRKDC	IL6ST	0.847530595	6.04E-159
THCA	CGC	PRKDC	LATS1	0.854887837	1.41E-164
THCA	CGC	PRKDC	PIK3CA	0.858778205	1.10E-167
THCA	CGC	PRKDC	TRIP11	0.870513007	1.19E-177
THCA	CGC	PRKDC	PAFAH1B2	0.886000015	2.11E-192
THCA	CGC	PRKDC	ASXL2	0.886402053	8.17E-193
THCA	CGC	PRKDC	STRN	0.890306966	6.87E-197
THCA	Epifactor	PRKDC	RSF1	0.803156008	2.59E-130
THCA	Epifactor	PRKDC	SUPT16H	0.805345939	1.50E-131
THCA	Epifactor	PRKDC	NBN	0.806037977	6.07E-132
THCA	Epifactor	PRKDC	PHF20	0.813794253	1.81E-136
THCA	Epifactor	PRKDC	BAZ1B	0.814538538	6.50E-137
THCA	Epifactor	PRKDC	RAD54L2	0.814723709	5.04E-137
THCA	Epifactor	PRKDC	USP12	0.816567139	3.88E-138
THCA	Epifactor	PRKDC	CLOCK	0.821695749	2.66E-141
THCA	Epifactor	PRKDC	GTF3C4	0.823618041	1.63E-142
THCA	Epifactor	PRKDC	PBRM1	0.824404859	5.16E-143
THCA	Epifactor	PRKDC	REST	0.827695989	3.91E-145
THCA	Epifactor	PRKDC	PPP4R2	0.835227342	3.68E-150
THCA	Epifactor	PRKDC	KDM5A	0.841846563	8.57E-155
THCA	Epifactor	PRKDC	NCOA2	0.843962816	2.55E-156
THCA	Epifactor	PRKDC	EYA3	0.84426788	1.53E-156
THCA	Epifactor	PRKDC	RBBP5	0.844427212	1.17E-156
THCA	Epifactor	PRKDC	RNF168	0.847997617	2.71E-159
THCA	Epifactor	PRKDC	HUWE1	0.850745944	2.27E-161
THCA	Epifactor	PRKDC	PARG	0.852190893	1.77E-162
THCA	Epifactor	PRKDC	SMARCA5	0.853839899	9.31E-164
THCA	Epifactor	PRKDC	MAP3K7	0.868194276	1.32E-175
THCA	Epifactor	PRKDC	DDX21	0.87314293	5.13E-180
THCA	Epifactor	PRKDC	ASXL2	0.886402053	8.17E-193
THCA	IUPHAR	PRKDC	SLC30A1	0.80249237	6.09E-130
THCA	IUPHAR	PRKDC	SLK	0.805487069	1.25E-131
THCA	IUPHAR	PRKDC	ERN1	0.80851	2.31E-133
THCA	IUPHAR	PRKDC	USP14	0.810573545	1.45E-134
THCA	IUPHAR	PRKDC	USP1	0.810830673	1.03E-134
THCA	IUPHAR	PRKDC	SCYL2	0.811419519	4.64E-135
THCA	IUPHAR	PRKDC	GART	0.812106212	1.82E-135
THCA	IUPHAR	PRKDC	SAMD8	0.812956235	5.72E-136
THCA	IUPHAR	PRKDC	BAZ1B	0.814538538	6.50E-137
THCA	IUPHAR	PRKDC	UGCG	0.817175464	1.66E-138
THCA	IUPHAR	PRKDC	WNK1	0.81889825	1.46E-139
THCA	IUPHAR	PRKDC	CLOCK	0.821695749	2.66E-141
THCA	IUPHAR	PRKDC	SLC30A6	0.822311525	1.09E-141
THCA	IUPHAR	PRKDC	ABHD2	0.823232529	2.87E-142
THCA	IUPHAR	PRKDC	GTF3C4	0.823618041	1.63E-142
THCA	IUPHAR	PRKDC	CDK12	0.82434491	5.64E-143
THCA	IUPHAR	PRKDC	PBRM1	0.824404859	5.16E-143
THCA	IUPHAR	PRKDC	DPP8	0.824459949	4.76E-143
THCA	IUPHAR	PRKDC	LMTK2	0.833626944	4.52E-149
THCA	IUPHAR	PRKDC	ADAM10	0.841721507	1.05E-154
THCA	IUPHAR	PRKDC	KDM5A	0.841846563	8.57E-155
THCA	IUPHAR	PRKDC	TAOK1	0.843061668	1.15E-155
THCA	IUPHAR	PRKDC	NCOA2	0.843962816	2.55E-156
THCA	IUPHAR	PRKDC	IL6ST	0.847530595	6.04E-159
THCA	IUPHAR	PRKDC	SPTLC2	0.849170057	3.56E-160
THCA	IUPHAR	PRKDC	LATS1	0.854887837	1.41E-164
THCA	IUPHAR	PRKDC	IDE	0.855143386	8.84E-165
THCA	IUPHAR	PRKDC	PIK3CA	0.858778205	1.10E-167
THCA	IUPHAR	PRKDC	CLCN3	0.859351833	3.76E-168
THCA	IUPHAR	PRKDC	MAP3K7	0.868194276	1.32E-175
THCA	IUPHAR	PRKDC	PRKAR2A	0.870392347	1.53E-177
THCA	IUPHAR	PRKDC	MAP3K2	0.884947741	2.47E-191
THCA	IUPHAR	PRKDC	LNPEP	0.886897287	2.53E-193
THCA	Kinase	PRKDC	SLK	0.805487069	1.25E-131
THCA	Kinase	PRKDC	ERN1	0.80851	2.31E-133
THCA	Kinase	PRKDC	SCYL2	0.811419519	4.64E-135
THCA	Kinase	PRKDC	BAZ1B	0.814538538	6.50E-137
THCA	Kinase	PRKDC	WNK1	0.81889825	1.46E-139
THCA	Kinase	PRKDC	CDK12	0.82434491	5.64E-143
THCA	Kinase	PRKDC	LMTK2	0.833626944	4.52E-149
THCA	Kinase	PRKDC	TAOK1	0.843061668	1.15E-155
THCA	Kinase	PRKDC	LATS1	0.854887837	1.41E-164
THCA	Kinase	PRKDC	MAP3K7	0.868194276	1.32E-175
THCA	Kinase	PRKDC	MAP3K2	0.884947741	2.47E-191
THCA	TF	PRKDC	ZBTB38	0.80174742	1.58E-129
THCA	TF	PRKDC	ZNF134	0.806821501	2.17E-132
THCA	TF	PRKDC	ZNF813	0.811250467	5.83E-135
THCA	TF	PRKDC	PHF20	0.813794253	1.81E-136
THCA	TF	PRKDC	ZKSCAN1	0.816065089	7.82E-138
THCA	TF	PRKDC	CLOCK	0.821695749	2.66E-141
THCA	TF	PRKDC	REST	0.827695989	3.91E-145
THCA	TF	PRKDC	ZNF623	0.828680766	8.89E-146
THCA	TF	PRKDC	ZNF426	0.835816701	1.45E-150
THCA	TF	PRKDC	NCOA2	0.843962816	2.55E-156
THCA	TF	PRKDC	ETV3	0.84579788	1.16E-157
THCA	TF	PRKDC	ZFP91	0.87269351	1.31E-179
THCA	TF	PRKDC	ATF6	0.892458617	3.35E-199
THCA	TSG	PRKDC	NBN	0.806037977	6.07E-132
THCA	TSG	PRKDC	PTPN11	0.810686287	1.25E-134
THCA	TSG	PRKDC	USP12	0.816567139	3.88E-138
THCA	TSG	PRKDC	PBRM1	0.824404859	5.16E-143
THCA	TSG	PRKDC	RNF111	0.839754591	2.63E-153
THCA	TSG	PRKDC	KDM5A	0.841846563	8.57E-155
THCA	TSG	PRKDC	LATS1	0.854887837	1.41E-164
THCA	TSG	PRKDC	ANAPC1	0.858138885	3.62E-167
THYM	Cell metabolism gene	PRKDC	NUP155	0.808365486	2.18E-29
UCS	Cell metabolism gene	PRKDC	NUP155	0.808365486	2.18E-29
UVM	Cell metabolism gene	PRKDC	PAFAH1B1	0.805613442	2.05E-19
UVM	Cell metabolism gene	PRKDC	NUP205	0.807602946	1.43E-19
UVM	Cell metabolism gene	PRKDC	GFPT1	0.80925923	1.06E-19
UVM	Cell metabolism gene	PRKDC	OXCT1	0.81542024	3.32E-20
UVM	Cell metabolism gene	PRKDC	SLC25A32	0.816674605	2.61E-20
UVM	Cell metabolism gene	PRKDC	PIK3C2A	0.818565992	1.81E-20
UVM	Cell metabolism gene	PRKDC	IQGAP1	0.82055261	1.23E-20
UVM	Cell metabolism gene	PRKDC	NCOA2	0.832528391	1.06E-21
UVM	Cell metabolism gene	PRKDC	TGS1	0.853771164	8.16E-24
UVM	CGC	PRKDC	TCEA1	0.825733741	4.35E-21
UVM	CGC	PRKDC	NCOA2	0.832528391	1.06E-21
UVM	CGC	PRKDC	UBR5	0.841550832	1.46E-22
UVM	Epifactor	PRKDC	NCOA2	0.832528391	1.06E-21
UVM	Epifactor	PRKDC	CHD7	0.835200425	5.96E-22
UVM	Epifactor	PRKDC	UBR5	0.841550832	1.46E-22
UVM	Epifactor	PRKDC	TAF2	0.853252677	9.27E-24
UVM	IUPHAR	PRKDC	LYN	0.800852123	4.78E-19
UVM	IUPHAR	PRKDC	SLC25A32	0.816674605	2.61E-20
UVM	IUPHAR	PRKDC	PIK3C2A	0.818565992	1.81E-20
UVM	IUPHAR	PRKDC	ATP6V1H	0.819843624	1.41E-20
UVM	IUPHAR	PRKDC	IDE	0.824420438	5.68E-21
UVM	IUPHAR	PRKDC	NIPAL2	0.825371614	4.68E-21
UVM	IUPHAR	PRKDC	NCOA2	0.832528391	1.06E-21
UVM	IUPHAR	PRKDC	NSMAF	0.854945705	6.10E-24
UVM	Kinase	PRKDC	LYN	0.800852123	4.78E-19
UVM	TF	PRKDC	E2F5	0.80383456	2.82E-19
UVM	TF	PRKDC	TERF1	0.814594257	3.89E-20
UVM	TF	PRKDC	ZBTB10	0.822256391	8.76E-21
UVM	TF	PRKDC	NCOA2	0.832528391	1.06E-21
UVM	TF	PRKDC	ZNF704	0.891190763	1.68E-28
UVM	TSG	PRKDC	PAFAH1B1	0.805613442	2.05E-19

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Protein structure

Protein 3D structure
Visit iCn3D.

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Protein-Protein Interaction

Protein-protein interaction networks
* Overlap between up-regulated DEGs (log2FC<-1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

Overlap between down-regulated DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

* Edge colors based on TCGA cancer types.

* Overlap between DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network per cancer (center: Translation factor, node: DEGs, node color: log2FC, edges: weighted by -log2(adj.P))

Cancer type	Translation factor	Interacting protein coding gene	FC	adj.pval
LUSC	PRKDC	EGFR	1.32757138391417	0.000102202753672845
KICH	PRKDC	XRCC4	2.11100957260221	0.000102996826171875
KICH	PRKDC	DCLRE1C	1.07444505688144	0.000139892101287842
LIHC	PRKDC	XRCC4	-1.18440159546171	0.000529193301161068
PRAD	PRKDC	NHEJ1	1.40018239204779	0.000931746432967977
STAD	PRKDC	DCLRE1C	1.1838370246288	0.00123529229313135
LIHC	PRKDC	EGFR	-1.2230538094017	0.00496795806084514
COAD	PRKDC	PARP1	-2.00025046442025	0.00513318181037904
STAD	PRKDC	XRCC5	-1.13905799910803	0.00571200484409928
ESCA	PRKDC	XRCC5	-1.80815626633822	0.0068359375
LUSC	PRKDC	XRCC4	-2.8216265089893	0.00809684737265147
KIRP	PRKDC	NHEJ1	-1.3679237502222	0.0093395933508873
THCA	PRKDC	LIG4	-1.30114494135367	0.010391026276801
HNSC	PRKDC	XRCC6	1.19792131269296	0.0120438377739447
UCEC	PRKDC	TP53	2.03295038376694	0.015625
PRAD	PRKDC	PARP1	-1.27729527681234	0.0194951957597077
CHOL	PRKDC	PARP1	-6.57241770799102	0.01953125
ESCA	PRKDC	PARP1	-1.42911976344386	0.0244140625
ESCA	PRKDC	XRCC6	-1.01974255926718	0.0244140625
LUAD	PRKDC	AKT1	-4.53714460696341	0.0301695351050489
KIRP	PRKDC	XRCC5	-1.35302380385852	0.0375871751457453
KIRP	PRKDC	EGFR	1.14056399927375	0.0394268441013992
KICH	PRKDC	XRCC5	2.7147179025319	1.19209289550781e-07
KIRC	PRKDC	DCLRE1C	-1.319953128692	1.22649277245998e-06
LUAD	PRKDC	LIG4	-1.97327834259921	1.26146870510352e-05
BRCA	PRKDC	XRCC5	1.75691805147044	1.64431569238697e-12
BRCA	PRKDC	LIG4	-7.459293598124	1.76298679685816e-05
STAD	PRKDC	PARP1	-1.63619585694616	1.80229544639588e-05
KIRC	PRKDC	EGFR	1.55836383937799	2.25998111659284e-12
LIHC	PRKDC	PARP1	-2.4088413550282	2.56696988045444e-05
KIRC	PRKDC	TP53	-1.43050981150632	4.58942580328929e-09
THCA	PRKDC	TP53	-1.81960143635647	6.18215597921662e-07
LIHC	PRKDC	XRCC6	-2.01919589586495	9.38602278996449e-06
KIRP	PRKDC	LIG4	-2.82415109063821	9.90275293588639e-06

Protein-protein interactors with this translation factor (BIOGRID-3.4.160)

PPI interactors with PRKDC

AR, AP1B1, ATM, BRCA1, CHEK1, E4F1, LIG4, MRE11A, RAD17, RBBP8, TP53, WRN, NCOA6, KAT2A, RPA2, XRCC6, RPA1, ABL1, XRCC5, C1D, IKBKB, CHUK, AKT2, LYN, ILF3, ILF2, EIF2S2, NCF1, NCF2, NCF4, MAPK8, MAPK9, PCNA, CIB1, DCLRE1C, HSF1, CDC5L, HDLBP, RECQL5, MLH1, PMS2, SIRT6, AIRE, TTI1, TELO2, ATG4C, BECN1, ATG101, CAMKK2, CLN3, DDA1, GBAS, PRKAB2, POU2F1, MKNK1, NR1H4, CHD1L, ESR1, PARP1, KAT5, TTI2, SAP25, H2AFX, MGMT, PDX1, HIST1H1A, AICDA, DHX9, HIST1H1C, XRCC4, YY1, KAT8, MSL3, THRA, THRB, HDAC3, BIRC5, BMI1, CHAF1A, PPP2CA, PPP6C, PPP6R1, PPP6R2, PPP6R3, PRKDC, HIST1H3E, H3F3A, MYC, RYK, YWHAQ, USF1, HDAC5, Them6, SP1, HOXB7, PIDD1, SMARCAD1, NBN, ATRIP, RAD21, HDGF, CTDP1, tat, CENPA, LMNA, MSH6, TERF1, MDC1, ELAVL1, SIRT7, CSNK2A1, HIST1H3A, Cebpb, HNRNPA1, HNRNPC, ERG, PINK1, CUL3, CUL5, CDK2, COPS5, ARHGEF6, VPRBP, LRRK2, MBP, GRK5, SHC1, AP2M1, UBXN6, XPA, NR3C1, EFTUD2, DDX5, PRPF8, HSPA8, SF3B6, CWC27, THOC6, YBX1, TRA2B, U2AF2, RBM25, DHX38, SRP14, RPS11, SMARCA5, SRSF10, SRP54, PHGDH, RANBP2, PTER, THYN1, TPR, PGR, NOTCH1, IKBKAP, AKT1, PNKP, GSK3A, GSK3B, SRF, JUN, HSP90AA1, HSP90AB1, FN1, VCAM1, GZMB, UL29, NOS2, ITGA4, vpu, CFTR, CASP3, EIF4EBP1, CHEK2, PAN2, RUVBL1, HDAC11, ADRB2, BAG3, EGFR, IQCB1, FBXO6, CTPS2, GTF2I, PRDX1, C14orf166, RTCB, EHD1, FLII, LRRFIP1, METTL1, NUCB1, RFC2, SNRPA, rev, RPA3, ASB5, LGR4, PHKG2, ILK, ATRX, STAU1, EMD, RELA, RNF144A, CUL7, OBSL1, CCDC8, UBE2I, EED, AUP1, FOXRED2, UBAC2, FAF2, HHV8GK18_gp81, SUMO2, EP300, RASSF1, NTRK1, SCARNA22, NUP85, NUP107, NUP35, gag, CLK1, HSPA5, DNAJC7, POT1, TINF2, DCLRE1B, Ruvbl2, Terf1, Ruvbl1, Ppp6c, Bag2, Ppp6r1, SKI, CRY1, CRY2, ANAPC2, FZR1, CCNB1, MCM2, SNW1, MEX3C, POU5F1, ALOX15, NFATC2, AHSA1, XRCC1, CDC73, ATOH1, IGF1R, RRM2, MTOR, VHL, CDK4, CDK9, AKTIP, ZNF746, EPHA1, LPAR4, FANCD2, MTNR1B, CYLD, TRIM25, TES, MTF1, LNX1, HIF1A, ZNF598, BMPR1A, EGLN3, TOP1, POLD1, SLC25A1, RMND5A, RIPK4, TMPO, PPEF1, TPTE, CSNK1A1, BCL2L1, COPE, CTNNB1, TGFB1, RAD18, AAR2, PIH1D1, NKX2-1, CHD3, RNF4, CHD4, CDC34, SPDL1, RIOK1, HEXIM1, LARP7, RNF123, SNAI1, AGR2, RECQL4, DCPS, WWP1, TSPO, HMGA1, APEX1, CDC25A, LTC4S, EDA, DCK, ERBB2, RPS6KA2, BCAT2, CDC25B, SSTR4, DCXR, PIM1, PLA2G4C, JAK3, PFKFB4, CHD1, WDR76, HIST1H4A, HIST1H2BB, HIST1H2AB, CDK5RAP2, GRWD1, KIAA1429, METTL3, METTL14, USP18, ZBTB7A, FH, PHB, RBX1, ZC3H7A, RUVBL2, TPT1, TMEM41B, FLNA, USP14, NR2C2, UCHL3, UBQLN2, TRIM29, HDAC2, CTCF, MECOM, ATXN3, VRK1, TCF7L2, BCL2L14, MS4A4A, SLC15A3, TNFSF13B, UNC93B1, P2RY6, PELI1, HSPB1, DUSP2, PTPRU, ITFG1, ARAF, BIRC3, LMBR1L, NFX1, WWP2, BRD7, TRIM28, PLEKHA4, SETD1A, YAP1, TFCP2, ORF7a, M, PTEN, HELLS, BAD, ELK1, PTPN12, RAB5A, RHOA, SOCS1, EMC1, EMC2, MMGT1, KIAA1217, ANXA2, FAM161A, PWWP2B, SYNJ2, RNF8, TBC1D28, NRXN1, LAMC3, ZNF840P, TIAM2, CPN1, SYNE2, GTPBP4, MN1, SNIP1, ANKRD55, SFPQ, nsp7, nsp8, ORF6, SMC1A, SMC3, STAG2, PDS5A, CDCA5, MAU2, UBR5, NEK4, LRRC31, DUX4, CIT, ANLN, AURKB, CHMP4B, CHMP4C, ECT2, KIF14, KIF20A, KIF23, PRC1, Rnf183, BRD4, NINL, NUPR1, CIC, Apc2, RBM39, FBP1, Yap1, BKRF1, KDF1, ISG15, PARK2, UFL1, DDRGK1, IKBKG, TRIM37, WDR5, PAGE4, NUDCD2, NAA40, BGLT3, PBXIP1, PTH2R, LRRC25, MAS1, CHRM4, DRD4, CD80, MGARP, KIR2DL4, VASN, KLRK1, CRLF2, FPR1, IGHD, C19orf38, ADAM11, GPR17, MAGEA8, MLNR, C3orf18, DGCR2, GPR182, EFNA4, P2RY10, IL13RA2, CLSTN1, CHRM3, SLC22A15, CD274, GPRC5D, TACR3, NPY2R, ITFG3, SLC15A1, OPALIN, HLA-B, DTX3, SPRTN, BTF3, FBXW7, TMPRSS2, TOP3B, CTSL, CTSB, FURIN, CTSS, DPP4, IFITM3, TMPRSS11B, CLEC4D, ACE2, CLEC4E, nsp1, nsp15, nsp5, S, nsp4, PRKAA2, PRKAG1, UHRF2, TOLLIP, NHEJ1, HDAC6, CUL1, DGCR8, PLK1, ZEB1,

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Mutations

Clinically associated variants from ClinVar.

Gene	Chr	Position	RefSeq	VarSeq	RefSeeq	VarType	Pathogenic	Disease	VarInfo
PRKDC	chr8	48686746	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48686778	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48686820	C	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48686829	G	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48686838	C	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48686905	A	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48686942	GA	G	Deletion	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48687031	C	G	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48689366	C	T	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48689431	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48689445	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48689449	G	A	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48689454	A	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48689465	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48689473	C	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48689481	T	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48689538	C	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48689560	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48689773	A	AT	Duplication	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48689773	AT	A	Deletion	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48690066	A	G	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48690186	A	G	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48690240	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48690244	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48690263	G	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48690271	G	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48690291	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48690299	A	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48690311	G	A	single_nucleotide_variant	Uncertain_significance	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48690322	C	T	single_nucleotide_variant	Likely_benign	not_specified	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48690335	A	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48690345	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48690349	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48690354	G	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48690358	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48690359	G	A	single_nucleotide_variant	Uncertain_significance	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48690369	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48690378	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48690395	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48690424	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48690558	C	T	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48691014	G	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48691028	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48691029	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48691038	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48691059	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48691064	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48691067	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48691068	G	A	single_nucleotide_variant	Benign/Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_specified\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48691079	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48691107	G	A	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48691113	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48691119	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48691160	C	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48691175	G	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48691177	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48691188	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48691206	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48691220	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48691280	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48691290	T	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48691305	G	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48691325	C	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48691334	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48691350	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48691357	G	A	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48691583	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48691595	T	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48691632	C	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48691636	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48691637	G	A	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48691639	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48691655	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001574\|splice_acceptor_variant	SO:0001574\|splice_acceptor_variant
PRKDC	chr8	48691906	C	T	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48694521	A	C	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48694746	T	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant,SO:0001627\|intron_variant	SO:0001583\|missense_variant,SO:0001627\|intron_variant
PRKDC	chr8	48694956	A	G	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48694969	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48694998	G	A	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48695013	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48695046	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48695047	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48695059	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48695089	G	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48695094	T	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48695098	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48695103	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48695113	C	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48695181	C	A	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48695210	C	T	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48695211	T	G	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48695447	T	C	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48696318	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48696319	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48696356	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48696357	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48696360	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48696598	T	C	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48697424	C	G	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48697675	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48697675	G	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48697705	C	T	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48697733	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48697752	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48697802	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48697855	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48697877	G	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48701329	G	A	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48701502	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48701505	C	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48701537	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48701583	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48701591	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48701595	C	A	single_nucleotide_variant	Likely_benign	not_specified	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48701596	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48701618	G	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48701621	A	G	single_nucleotide_variant	Likely_benign	not_specified	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48701720	G	A	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48701749	G	A	single_nucleotide_variant	Pathogenic	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48701770	A	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48701786	A	T	single_nucleotide_variant	Benign/Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_specified\|not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48706854	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48706884	G	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48706895	G	A	single_nucleotide_variant	Benign/Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48706943	C	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48706943	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48706953	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48706988	G	A	single_nucleotide_variant	Likely_benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48706997	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48707019	T	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48707035	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48707053	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48707335	T	G	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48710684	G	A	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48710814	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48710835	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48710880	T	C	single_nucleotide_variant	Benign/Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_specified\|not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48710894	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48710909	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48710933	C	T	single_nucleotide_variant	Likely_benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48710934	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48710955	A	G	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_specified	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48710970	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48711467	T	A	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48711682	C	G	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48711758	A	T	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48711775	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48711777	C	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48711793	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48711794	C	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48711795	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48711804	G	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48711824	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48711857	C	T	single_nucleotide_variant	Benign/Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_specified	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48711862	G	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48711872	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48711881	GCCT	G	Microsatellite	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001822\|inframe_deletion	SO:0001822\|inframe_deletion
PRKDC	chr8	48711896	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48711904	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48711926	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48713359	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48713404	C	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48713416	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48713428	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48713433	G	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48713456	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48713457	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48713485	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48713488	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48713504	A	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48713527	A	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48713532	GAC	G	Microsatellite	Uncertain_significance	not_provided	SO:0001589\|frameshift_variant	SO:0001589\|frameshift_variant
PRKDC	chr8	48713537	G	A	single_nucleotide_variant	Benign/Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_specified	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48713538	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48713540	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48713557	T	TA	Duplication	Benign/Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_specified	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48715854	G	A	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_specified	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48715864	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48715919	G	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48715924	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48715944	C	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48715944	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48715952	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48715978	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48715979	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48715985	G	C	single_nucleotide_variant	Likely_benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48716001	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48716005	G	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48716006	C	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48716028	A	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48716037	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48719705	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48719721	T	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48719721	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48719744	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48719752	G	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48719844	G	A	single_nucleotide_variant	Benign/Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_specified\|not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48719852	G	C	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48719887	T	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48719895	A	G	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48729746	G	A	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48729811	T	C	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48729960	C	T	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48730003	C	T	single_nucleotide_variant	Benign/Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_specified	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48730007	T	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48730014	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48730054	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48730058	A	G	single_nucleotide_variant	Likely_benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48730064	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48730081	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48730106	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48730122	C	T	single_nucleotide_variant	Benign/Likely_benign	Malignant_tumor_of_breast\|Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_specified	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48730131	A	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48730400	C	A	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48731966	G	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48732009	C	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48732023	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48732033	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48732074	T	TA	Duplication	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48732074	T	TAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA	Insertion	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48732074	TA	T	Deletion	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48732074	TAA	T	Deletion	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48732074	TAAA	T	Deletion	Benign/Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48732075	A	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48733276	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48733324	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48733389	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48733390	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48733399	G	A	single_nucleotide_variant	Benign/Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48733405	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48733431	A	C	single_nucleotide_variant	Pathogenic	Immunodeficiency_26_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48733446	G	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48733452	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48733471	G	A	single_nucleotide_variant	Benign/Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_specified	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48733479	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48734172	A	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48734205	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48734246	T	A	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48734258	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48734290	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48734324	A	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48734360	G	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48734371	A	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48736459	G	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48736484	T	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48736522	C	T	single_nucleotide_variant	Conflicting_interpretations_of_pathogenicity	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48736554	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48736557	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48736565	A	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48739233	A	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48739256	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48739257	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48739268	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48739305	G	A	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_specified	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48739308	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48739315	C	T	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48739318	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48739321	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48739338	C	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48739338	C	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48739338	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48739339	G	A	single_nucleotide_variant	Benign/Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_specified	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48739348	T	C	single_nucleotide_variant	Likely_benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48739387	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48739401	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48739421	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48739440	C	A	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_specified	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48740550	TG	T	Deletion	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48740753	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48740812	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48740837	A	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48740848	T	C	single_nucleotide_variant	Uncertain_significance	Microcephaly	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48740849	C	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48740886	T	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48740899	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48740922	A	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48741171	A	G	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48743175	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48743180	G	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48743185	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48743206	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48743236	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48743237	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48743238	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48743246	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48743271	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48743289	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48743295	T	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48743307	C	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48743307	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48744370	C	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48744382	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48744411	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48744462	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48744467	G	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48744470	C	CTG	Insertion	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001589\|frameshift_variant	SO:0001589\|frameshift_variant
PRKDC	chr8	48744473	T	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48744477	G	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48744484	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48744487	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48746761	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48746779	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48746805	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48746845	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48746848	C	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48746860	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48746866	G	A	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48746878	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48746905	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48746912	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48746949	T	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48746955	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48746967	G	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48747246	A	ACTT	Duplication	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48748881	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48748915	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48748925	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48748958	A	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48748960	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48748967	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48748968	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48748976	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48748991	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48748994	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48748995	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48749008	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48749017	G	A	single_nucleotide_variant	Conflicting_interpretations_of_pathogenicity	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48749039	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48749042	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48749057	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48749064	G	A	single_nucleotide_variant	Uncertain_significance	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48749068	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48749763	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48749764	C	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48749784	A	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48749803	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48749810	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48749840	A	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48749848	C	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48749856	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48749878	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48749882	T	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48749885	A	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48749887	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48749899	T	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48749901	A	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48749934	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48749953	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48751788	C	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48751797	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48751803	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48751813	T	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48752082	G	A	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48752567	T	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48752592	A	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48752600	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48752617	G	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48752626	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48752647	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48752648	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48752656	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48752659	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48752660	G	A	single_nucleotide_variant	Conflicting_interpretations_of_pathogenicity	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48752676	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48752700	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48761742	T	C	single_nucleotide_variant	Uncertain_significance	Microcephaly	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48761750	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48761765	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48761791	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_specified	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48761797	C	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48761837	C	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48761869	C	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48761869	C	T	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48761872	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48761924	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48761956	G	A	single_nucleotide_variant	Uncertain_significance	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48761962	T	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48761978	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48761990	A	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48762007	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48762009	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48762034	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48762060	A	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48765089	T	C	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48765287	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48765288	G	A	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48765303	A	G	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48765322	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48765338	G	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48765348	A	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48766674	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48766679	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48766685	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48766700	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48766727	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48766735	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48766753	C	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48766765	C	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001587\|nonsense	SO:0001587\|nonsense
PRKDC	chr8	48766783	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48767518	C	G	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48767560	G	A	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48767773	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48767785	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48767838	C	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48767859	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48767909	G	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48767923	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48769719	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48769749	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48769773	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48769811	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48769843	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48769846	G	A	single_nucleotide_variant	Benign/Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_specified	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48769853	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48769869	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48770975	T	C	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48771028	C	A	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48771083	T	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48771084	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48771101	G	C	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48771127	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48771128	T	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48771131	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48771145	G	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48771172	A	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48771180	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48771194	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48771243	T	C	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48771291	C	CA	Duplication	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48771301	T	C	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48771400	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48771413	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48771414	TCTC	T	Deletion	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001822\|inframe_deletion	SO:0001822\|inframe_deletion
PRKDC	chr8	48771425	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48771426	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48771428	G	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48771430	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48771435	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48771441	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48771452	G	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48771464	C	T	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48771471	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48771475	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48771487	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48771525	T	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48771527	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48771540	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48771550	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48771551	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48771552	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48771674	G	A	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48772173	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48772178	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48772190	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48772238	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48772244	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48772307	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48772312	A	G	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_specified	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48772402	A	G	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48772414	C	T	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48773432	C	T	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48774629	T	C	single_nucleotide_variant	Likely_benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48774631	C	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48774641	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48774645	T	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48774648	C	T	single_nucleotide_variant	Uncertain_significance	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48774649	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48774651	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48774652	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48774698	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48774918	C	T	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48774985	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48775008	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48775012	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48775016	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48775035	A	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48775040	C	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48775092	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48775093	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48775094	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48775099	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48775106	CAG	C	Microsatellite	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48775111	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48775205	C	T	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48775953	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48775954	TCTTA	T	Microsatellite	Uncertain_significance	not_specified	SO:0001575\|splice_donor_variant	SO:0001575\|splice_donor_variant
PRKDC	chr8	48775999	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48776001	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48776007	A	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48776016	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48776065	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48776076	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48776085	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48776121	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48776134	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48776142	C	T	single_nucleotide_variant	Conflicting_interpretations_of_pathogenicity	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48776189	C	T	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48777112	G	A	single_nucleotide_variant	Conflicting_interpretations_of_pathogenicity	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48777129	G	A	single_nucleotide_variant	Uncertain_significance	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48777138	C	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48777151	T	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48777155	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48777161	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48777191	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48777221	A	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48777222	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48777223	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48777225	G	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48777260	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48790280	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48790283	A	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001575\|splice_donor_variant	SO:0001575\|splice_donor_variant
PRKDC	chr8	48790292	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48790327	A	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48790329	G	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48790332	A	G	single_nucleotide_variant	Likely_benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48790379	T	C	single_nucleotide_variant	Uncertain_significance	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48790395	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48790664	G	GT	Duplication	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48791842	T	C	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48792042	A	T	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48792046	A	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48792077	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48792085	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48792125	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48792167	A	T	single_nucleotide_variant	Conflicting_interpretations_of_pathogenicity	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48792180	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48792199	A	C	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_specified	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48792206	G	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48792208	G	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48793644	CAAGA	C	Deletion	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48793970	T	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48793983	A	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48794014	C	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48794018	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48794033	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48794048	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48794065	G	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48794090	A	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48794171	T	C	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48794465	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48794499	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48794518	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48794528	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48794552	T	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48794568	G	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48794574	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48794579	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48794579	G	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48794606	T	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48794626	C	A	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_specified	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48794649	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48794663	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48794906	C	T	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48798361	G	A	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48798507	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48798508	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48798519	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48798539	T	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48798543	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48798575	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48798578	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48798581	A	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48798599	C	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48798617	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48798630	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48798634	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48798651	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48798655	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48798662	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48798662	G	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48798687	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48798701	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48798718	AG	GT	Indel	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48800114	T	C	single_nucleotide_variant	Likely_benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48800194	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48800211	C	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48800245	C	G	single_nucleotide_variant	Conflicting_interpretations_of_pathogenicity	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_specified\|not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48800250	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48800565	C	T	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48800981	G	A	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48801040	A	G	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48801072	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48801085	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48801095	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48801098	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48801100	C	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48801106	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48801117	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48801121	C	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48801121	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48801138	C	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48801142	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48801150	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48801170	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48801171	C	T	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48801172	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48801178	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48801182	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48801184	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48801192	C	T	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48801208	A	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48801210	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48801554	G	A	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48801562	C	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48801584	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48801621	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48801629	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48801676	A	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48801677	G	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48801691	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48801696	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48801701	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48801717	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48801718	G	A	single_nucleotide_variant	Benign/Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_specified	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48801731	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48801738	C	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48801747	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48801771	CCTT	C	Microsatellite	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001822\|inframe_deletion	SO:0001822\|inframe_deletion
PRKDC	chr8	48801790	C	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48801791	AGATT	A	Deletion	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48802046	G	A	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48802573	G	A	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48802690	T	TATA	Microsatellite	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48802690	TATA	T	Microsatellite	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48802830	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48802837	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48802837	G	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48802875	C	T	single_nucleotide_variant	Likely_benign	not_specified	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48802880	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48802948	C	A	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48802958	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48802968	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48802969	A	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48802970	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48802978	T	C	single_nucleotide_variant	Uncertain_significance	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48802979	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48802991	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48803004	A	C	single_nucleotide_variant	Likely_benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48803048	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48803055	T	A	single_nucleotide_variant	Likely_benign	not_specified	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48805697	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48805713	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48805714	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48805726	C	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48805727	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48805744	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48805759	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48805760	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48805765	A	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48805773	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48805788	C	T	single_nucleotide_variant	Benign/Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_specified	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48805803	G	A	single_nucleotide_variant	Conflicting_interpretations_of_pathogenicity	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48805806	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48805815	A	AC	Insertion	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001589\|frameshift_variant	SO:0001589\|frameshift_variant
PRKDC	chr8	48805816	A	AGG	Duplication	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001589\|frameshift_variant	SO:0001589\|frameshift_variant
PRKDC	chr8	48805816	A	G	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48805837	C	T	single_nucleotide_variant	Conflicting_interpretations_of_pathogenicity	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48805848	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48805878	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48805914	A	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48805924	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48805938	G	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48805955	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48809730	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48809737	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48809737	G	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48809745	A	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48809757	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48809772	A	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48809777	G	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48809792	C	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48809812	G	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48809830	CAAT	C	Deletion	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001822\|inframe_deletion	SO:0001822\|inframe_deletion
PRKDC	chr8	48809854	T	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48811032	C	T	single_nucleotide_variant	Likely_benign	not_specified	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48811044	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48811106	C	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48811126	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48812928	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48812929	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48812982	C	A	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48812982	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48813016	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48813036	T	TA	Duplication	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48813147	T	C	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48815134	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48815141	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48815142	A	G	single_nucleotide_variant	Uncertain_significance	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48815161	T	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48815176	C	T	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48815186	T	C	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_specified	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48815241	G	A	single_nucleotide_variant	Uncertain_significance	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48815247	TCTC	T	Deletion	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001822\|inframe_deletion	SO:0001822\|inframe_deletion
PRKDC	chr8	48815266	T	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48815293	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48815297	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48815306	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48815338	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48815346	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48815353	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48815354	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48817093	G	C	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48817411	G	T	single_nucleotide_variant	Benign/Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_specified	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48817412	AATCAACT	A	Deletion	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48817421	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48817434	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48817460	T	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48817502	T	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48817505	A	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48817516	C	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48817539	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48817590	G	A	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48824965	C	G	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_specified	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48825005	G	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48825013	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48825014	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48825064	T	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48825066	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48825070	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48825103	A	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48826333	TA	T	Deletion	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48826382	A	G	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48826456	A	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48826457	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48826482	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48826487	G	A	single_nucleotide_variant	Uncertain_significance	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48826498	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48826512	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48826525	A	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48826546	C	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48826575	C	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48826578	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48826580	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48826604	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48826613	C	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48826622	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48826927	T	C	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48827896	A	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48827905	T	C	single_nucleotide_variant	Uncertain_significance	Microcephaly	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48827906	T	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48827954	T	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48827976	G	A	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48830863	G	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48830868	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48830905	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48830930	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48830931	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48830942	A	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48839876	G	C	single_nucleotide_variant	Uncertain_significance	Microcephaly	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48839882	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48839882	G	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48839903	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48839909	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48839917	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48839920	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48840100	C	T	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48840324	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48840325	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48840339	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48840341	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48840345	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48840360	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48840370	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48840393	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48840394	A	G	single_nucleotide_variant	Likely_benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48840447	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48840469	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48840714	C	CT	Duplication	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48841617	CATG	C	Deletion	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48841679	A	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48841691	C	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48841708	G	A	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_specified	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48841710	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48842155	C	T	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48842425	T	C	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48842452	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48842464	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48842474	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48842494	A	G	single_nucleotide_variant	Conflicting_interpretations_of_pathogenicity	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48842497	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48842497	T	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48842505	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48842520	A	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48842554	T	C	single_nucleotide_variant	Benign/Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48842569	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48842582	C	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48842584	A	C	single_nucleotide_variant	Benign/Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48842889	G	A	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48843189	AC	A	Deletion	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48843246	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48843262	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48843281	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48843297	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48843305	C	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48843306	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48843310	G	C	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_specified	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48843315	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48843333	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48843926	T	C	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48844056	G	GT	Duplication	Pathogenic	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48845594	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48845596	G	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48845613	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48845628	A	C	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48845642	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48845643	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48845663	A	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48845680	C	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48845710	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48845711	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48845716	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48845726	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48846258	C	T	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48846519	T	C	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_specified	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48846558	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48846566	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48846567	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48846584	G	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48846609	T	C	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48846611	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48846613	C	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48846619	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48846622	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48846623	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48847564	T	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48847586	G	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48847628	G	GA	Duplication	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48847705	T	G	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48848281	T	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48848296	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48848350	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48848371	C	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48848401	G	T	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48848402	A	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48848427	G	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48848441	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48848464	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48848466	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48848632	AAC	A	Microsatellite	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48848933	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48848939	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48848955	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48848973	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48848978	C	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48848979	G	A	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48848988	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48849004	A	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48849020	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48849058	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48849060	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48849068	C	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48849075	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48849076	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48849078	C	T	single_nucleotide_variant	Uncertain_significance	not_provided	SO:0001574\|splice_acceptor_variant	SO:0001574\|splice_acceptor_variant
PRKDC	chr8	48849342	A	AT	Duplication	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48849342	AT	A	Deletion	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48852101	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48852114	T	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48852121	A	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48852162	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48852170	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48852184	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48852200	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48852207	C	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48852221	T	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48852225	C	T	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_specified\|not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48852233	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48852241	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48852267	C	A	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48852328	C	T	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48855811	C	T	single_nucleotide_variant	Likely_benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48855835	C	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48855864	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48855898	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48855900	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48856423	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48856427	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48856547	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48856555	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48866189	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48866208	C	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48866235	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48866246	C	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48866295	TAAG	T	Microsatellite	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48866369	GGGTCTTAAGTTCACCCAGAAAAGCGC	G	Deletion	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001589\|frameshift_variant	SO:0001589\|frameshift_variant
PRKDC	chr8	48866394	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_specified	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48866395	C	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48866416	T	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48866483	A	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48866483	A	T	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48866788	T	G	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48866881	A	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48866888	T	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48866889	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48866902	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48866909	A	AT	Duplication	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001589\|frameshift_variant	SO:0001589\|frameshift_variant
PRKDC	chr8	48866979	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48866980	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48866984	G	C	single_nucleotide_variant	Conflicting_interpretations_of_pathogenicity	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48867015	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48867152	G	A	single_nucleotide_variant	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48867273	G	C	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48868419	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48868427	TAA	T	Deletion	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48868440	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48868517	T	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48868517	T	TA	Duplication	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48869533	T	A	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48869538	C	A	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48869737	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48869755	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48869790	A	G	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48869821	A	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48869906	T	C	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48869923	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48869924	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48869967	G	T	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48869995	T	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48869997	C	CA	Duplication	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48870181	CTA	C	Deletion	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48872238	C	CA	Duplication	Likely_benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48872515	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001627\|intron_variant	SO:0001627\|intron_variant
PRKDC	chr8	48872535	A	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48872558	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48872566	C	G	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48872587	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48872600	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48872618	G	A	single_nucleotide_variant	Likely_benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48872630	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48872645	C	T	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_specified\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48872650	G	C	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48872653	G	A	single_nucleotide_variant	Likely_benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
PRKDC	chr8	48872670	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48872671	C	A	single_nucleotide_variant	Benign	Immunodeficiency_26_with_or_without_neurologic_abnormalities\|not_specified	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48872676	G	A	single_nucleotide_variant	Uncertain_significance	Immunodeficiency_26_with_or_without_neurologic_abnormalities	SO:0001583\|missense_variant	SO:0001583\|missense_variant
PRKDC	chr8	48872715	C	T	single_nucleotide_variant	Likely_benign	not_specified

nsSNVs with sample frequency (size of circle) from TCGA 33 cancers.

SNVs and Indels

Gene	Cancer type	Chromosome	Start	End	RefSeeq	MutSeq	Mutation type	AAchange	# samples
PRKDC	BLCA	chr8	48866910	48866910	T	-	Frame_Shift_Del	p.I166fs	11
PRKDC	THYM	chr8	48811087	48811087	C	T	Missense_Mutation	p.R1136H	7
PRKDC	GBM	chr8	48746799	48746799	T	-	Frame_Shift_Del	p.R2703fs	6
PRKDC	LIHC	chr8	48856412	48856412	C	A	Splice_Site		6
PRKDC	HNSC	chr8	48701554	48701555	-	T	Frame_Shift_Ins	p.N3604fs	5
PRKDC	LIHC	chr8	48701570	48701570	G	-	Frame_Shift_Del	p.P3599fs	4
PRKDC	CESC	chr8	48701765	48701765	G	C	Missense_Mutation		4
PRKDC	LIHC	chr8	48800117	48800117	A	-	Frame_Shift_Del	p.F1520fs	4
PRKDC	LIHC	chr8	48805816	48805816	A	G	Splice_Site		4
PRKDC	LGG	chr8	48866909	48866910	-	T	Frame_Shift_Ins	p.T166fs	4
PRKDC	UCEC	chr8	48749969	48749969	C	T	Missense_Mutation	p.R2521Q	4
PRKDC	KIRC	chr8	48840368	48840368	A	G	Missense_Mutation	p.I741T	4
PRKDC	BRCA	chr8	48839867	48839867	C	T	Missense_Mutation	p.G769D	3
PRKDC	HNSC	chr8	48719860	48719860	C	G	Missense_Mutation	p.E3194D	3
PRKDC	CESC	chr8	48701765	48701765	G	C	Missense_Mutation	p.Q3568E	3
PRKDC	BRCA	chr8	48839893	48839893	C	T	Silent	p.L760	3
PRKDC	LIHC	chr8	48868460	48868460	T	-	Frame_Shift_Del	p.I125fs	3
PRKDC	BRCA	chr8	48840380	48840380	G	A	Missense_Mutation	p.P737L	3
PRKDC	UCEC	chr8	48691202	48691202	T	A	Missense_Mutation	p.S3890C	3
PRKDC	UCEC	chr8	48696320	48696320	C	T	Missense_Mutation	p.A3719T	3
PRKDC	LIHC	chr8	48839799	48839799	T	C	Missense_Mutation		3
PRKDC	BRCA	chr8	48730110	48730110	G	C	Missense_Mutation	p.S3152C	3
PRKDC	BLCA	chr8	48777246	48777246	G	A	Silent		3
PRKDC	UVM	chr8	48849060	48849060	G	A	Silent		3
PRKDC	ESCA	chr8	48694817	48694817	T	G	Splice_Site		3
PRKDC	CESC	chr8	48800165	48800165	G	A	Silent		3
PRKDC	BRCA	chr8	48743255	48743255	C	T	Missense_Mutation	p.V2769I	3
PRKDC	HNSC	chr8	48805814	48805814	G	A	Missense_Mutation		3
PRKDC	BRCA	chr8	48761994	48761994	T	G	Missense_Mutation	p.K2358T	3
PRKDC	LUAD	chr8	48855770	48855770	T	A	Splice_Site	p.Q322_splice	3
PRKDC	LIHC	chr8	48792051	48792051	C	A	Splice_Site		3
PRKDC	BRCA	chr8	48765336	48765336	C	A	Missense_Mutation	p.Q2300H	3
PRKDC	UCEC	chr8	48686735	48686735	C	A	Nonstop_Mutation	p.*4128L	3
PRKDC	CHOL	chr8	48710796	48710796	A	G	Splice_Site		3
PRKDC	BLCA	chr8	48866215	48866215	G	T	Nonsense_Mutation	p.S229*	3
PRKDC	BRCA	chr8	48792059	48792059	A	T	Missense_Mutation	p.M1742K	3
PRKDC	HNSC	chr8	48855894	48855894	G	C	Missense_Mutation	p.Q281E	3
PRKDC	UCEC	chr8	48761804	48761804	A	C	Missense_Mutation	p.C2396W	3
PRKDC	HNSC	chr8	48845609	48845609	G	C	Missense_Mutation	p.L583V	3
PRKDC	ESCA	chr8	48734354	48734354	C	A	Splice_Site		3
PRKDC	CESC	chr8	48766714	48766714	G	C	Missense_Mutation		2
PRKDC	UCEC	chr8	48697820	48697820	A	C	Missense_Mutation	p.M3653R	2
PRKDC	UCEC	chr8	48798608	48798608	T	G	Missense_Mutation	p.Y1557S	2
PRKDC	UCEC	chr8	48840392	48840392	A	G	Missense_Mutation	p.L733P	2
PRKDC	SKCM	chr8	48866231	48866231	G	A	Silent	p.L224L	2
PRKDC	UCEC	chr8	48855904	48855904	C	T	Silent	p.L277	2
PRKDC	CESC	chr8	48761816	48761816	C	G	Missense_Mutation		2
PRKDC	LIHC	chr8	48852217	48852217	T	-	Frame_Shift_Del	p.N336fs	2
PRKDC	UCEC	chr8	48719714	48719714	T	C	Missense_Mutation	p.D3243G	2
PRKDC	SARC	chr8	48765289	48765289	G	C	Missense_Mutation	p.A2316G	2
PRKDC	UCEC	chr8	48762032	48762032	C	T	Silent	p.R2346Q	2
PRKDC	PAAD	chr8	48790367	48790367	A	C	Missense_Mutation	p.L1760V	2
PRKDC	BRCA	chr8	48694776	48694776	C	T	Silent	p.L3811	2
PRKDC	UCEC	chr8	48697866	48697866	C	A	Nonsense_Mutation	p.E3638*	2
PRKDC	UCEC	chr8	48798619	48798619	G	T	Silent	p.P1554H	2
PRKDC	UCEC	chr8	48842416	48842416	G	T	Missense_Mutation	p.F683L	2
PRKDC	BLCA	chr8	48771464	48771464	C	T	Silent	p.L2096L	2
PRKDC	UCEC	chr8	48866931	48866931	C	A	Nonsense_Mutation	p.E159*	2
PRKDC	ESCA	chr8	48773481	48773481	C	T	Missense_Mutation		2
PRKDC	SARC	chr8	48845610	48845610	T	G	Silent		2
PRKDC	UCEC	chr8	48740743	48740743	C	T	Missense_Mutation	p.V2854I	2
PRKDC	BRCA	chr8	48697854	48697855	-	T	Frame_Shift_Ins	p.H3641fs	2
PRKDC	LIHC	chr8	48744384	48744384	T	-	Frame_Shift_Del	p.K2751fs	2
PRKDC	UCEC	chr8	48765343	48765343	T	C	Missense_Mutation	p.Y2298C	2
PRKDC	HNSC	chr8	48798592	48798592	G	C	Missense_Mutation	p.F1562L	2
PRKDC	LIHC	chr8	48695065	48695065	T	A	Missense_Mutation		2
PRKDC	ESCA	chr8	48739330	48739330	G	C	Missense_Mutation		2
PRKDC	PAAD	chr8	48691355	48691355	G	A	Missense_Mutation	p.A3861V	2
PRKDC	CESC	chr8	48794602	48794602	C	G	Missense_Mutation	p.Q1610H	2
PRKDC	UCEC	chr8	48706963	48706963	C	A	Nonsense_Mutation	p.E3519*	2
PRKDC	UCEC	chr8	48802835	48802835	A	G	Missense_Mutation	p.S1351P	2
PRKDC	HNSC	chr8	48733339	48733339	G	A	Nonsense_Mutation	p.Q3092*	2
PRKDC	UCEC	chr8	48842495	48842495	G	A	Missense_Mutation	p.S657F	2
PRKDC	SKCM	chr8	48772186	48772186	G	A	Missense_Mutation	p.R2064C	2
PRKDC	UCEC	chr8	48869951	48869952	-	A	Frame_Shift_Ins	p.L65fs	2
PRKDC	ESCA	chr8	48773490	48773490	C	G	Missense_Mutation		2
PRKDC	THYM	chr8	48811087	48811087	C	T	Missense_Mutation		2
PRKDC	CESC	chr8	48794620	48794620	G	A	Silent		2
PRKDC	LUAD	chr8	48710830	48710830	G	C	Missense_Mutation	p.P3475A	2
PRKDC	UCEC	chr8	48740754	48740754	A	C	Missense_Mutation	p.F2850C	2
PRKDC	BRCA	chr8	48801132	48801132	C	A	Missense_Mutation	p.A1453S	2
PRKDC	ESCA	chr8	48691161	48691161	G	A	Silent	p.F3903F	2
PRKDC	LIHC	chr8	48752603	48752603	A	-	Frame_Shift_Del	p.I2475fs	2
PRKDC	SARC	chr8	48733396	48733396	G	A	Nonsense_Mutation	p.Q3073*	2
PRKDC	UCEC	chr8	48689458	48689458	T	G	Missense_Mutation	p.K4042N	2
PRKDC	UCEC	chr8	48766729	48766729	T	C	Missense_Mutation	p.N2269D	2
PRKDC	ACC	chr8	48689404	48689404	C	T	Splice_Site	.	2
PRKDC	PAAD	chr8	48743248	48743248	T	C	Missense_Mutation	p.Y2771C	2
PRKDC	CESC	chr8	48830905	48830905	G	A	Missense_Mutation	p.R820W	2
PRKDC	LUSC	chr8	48743256	48743256	G	C	Silent	p.V2768V	2
PRKDC	BRCA	chr8	48691190	48691190	C	T	Missense_Mutation	p.E3894K	2
PRKDC	UCEC	chr8	48710933	48710933	C	T	Silent	p.R3441H	2
PRKDC	UCEC	chr8	48802881	48802881	G	A	Silent	p.P1336L	2
PRKDC	UCEC	chr8	48843269	48843269	C	A	Missense_Mutation	p.D619Y	2
PRKDC	HNSC	chr8	48868498	48868498	G	A	Missense_Mutation	p.T112I	2
PRKDC	SKCM	chr8	48849077	48849077	G	A	Splice_Site	p.P372_splice	2
PRKDC	UCEC	chr8	48869957	48869957	G	A	Silent	p.F63	2
PRKDC	CESC	chr8	48839863	48839863	C	T	Silent		2
PRKDC	HNSC	chr8	48848436	48848436	G	C	Missense_Mutation	p.L435V	2
PRKDC	UCEC	chr8	48740760	48740760	G	A	Missense_Mutation	p.S2848F	2
PRKDC	BRCA	chr8	48811083	48811083	G	A	Silent	p.I1137	2
PRKDC	LIHC	chr8	48773466	48773466	C	-	Frame_Shift_Del	p.D2017fs	2
PRKDC	UCEC	chr8	48690334	48690334	T	C	Silent	p.Y3954C	2
PRKDC	UCEC	chr8	48767884	48767884	C	A	Missense_Mutation	p.M2219I	2
PRKDC	PAAD	chr8	48701608	48701608	A	G	Silent	p.D3586D	2
PRKDC	ESCA	chr8	48773481	48773481	C	T	Missense_Mutation	p.E2012K	2
PRKDC	PRAD	chr8	48769758	48769758	C	A	Missense_Mutation	p.V2189L	2
PRKDC	UCEC	chr8	48710934	48710934	G	A	Missense_Mutation	p.A3440V	2
PRKDC	UCEC	chr8	48811031	48811031	G	A	Nonsense_Mutation	p.R1155*	2
PRKDC	LUAD	chr8	48775080	48775080	C	A	Nonsense_Mutation	p.E1924*	2
PRKDC	UCEC	chr8	48843348	48843348	C	A	Splice_Site	e17-1	2
PRKDC	ESCA	chr8	48866998	48866998	C	T	Silent		2
PRKDC	CESC	chr8	48694968	48694968	C	T	Silent		2
PRKDC	SARC	chr8	48765289	48765289	G	C	Missense_Mutation		2
PRKDC	UCEC	chr8	48740782	48740782	G	T	Missense_Mutation	p.R2841S	2
PRKDC	BRCA	chr8	48839765	48839765	G	T	Nonsense_Mutation	p.S803*	2
PRKDC	LIHC	chr8	48792060	48792060	T	-	Frame_Shift_Del	p.M1742fs	2
PRKDC	UCEC	chr8	48691038	48691038	C	T	Silent	p.R3914H	2
PRKDC	UCEC	chr8	48771530	48771530	C	T	Silent	p.R2075Q	2
PRKDC	HNSC	chr8	48715931	48715931	G	A	Silent	p.C3285C	2
PRKDC	STAD	chr8	48701555	48701555	T	-	Frame_Shift_Del		2
PRKDC	LIHC	chr8	48839897	48839897	C	T	Missense_Mutation		2
PRKDC	ESCA	chr8	48776098	48776098	A	G	Missense_Mutation		2
PRKDC	PAAD	chr8	48691356	48691356	C	T	Missense_Mutation	p.A3861T	2
PRKDC	ESCA	chr8	48773490	48773490	C	G	Missense_Mutation	p.E2009Q	2
PRKDC	LIHC	chr8	48732069	48732069	A	G	Silent		2
PRKDC	CESC	chr8	48794602	48794602	C	G	Missense_Mutation		2
PRKDC	UCEC	chr8	48711895	48711895	C	T	Silent	p.R3391Q	2
PRKDC	UCEC	chr8	48815227	48815227	T	G	Missense_Mutation	p.K1057N	2
PRKDC	BLCA	chr8	48817520	48817520	T	C	Missense_Mutation	p.Y984C	2
PRKDC	LUAD	chr8	48744433	48744433	T	C	Missense_Mutation	p.Q2735R	2
PRKDC	UCEC	chr8	48845714	48845714	C	A	Nonsense_Mutation	p.E548*	2
PRKDC	HNSC	chr8	48798673	48798673	C	T	Silent	p.A1535A	2
PRKDC	UCEC	chr8	48744484	48744484	G	A	Missense_Mutation	p.A2718V	2
PRKDC	UCS	chr8	48801143	48801143	G	A	Missense_Mutation	p.A1449V	2
PRKDC	ESCA	chr8	48733437	48733437	G	A	Missense_Mutation		2
PRKDC	PAAD	chr8	48701608	48701608	A	G	Silent		2
PRKDC	CESC	chr8	48792189	48792189	T	C	Missense_Mutation		2
PRKDC	ESCA	chr8	48734271	48734271	T	C	Missense_Mutation		2
PRKDC	PAAD	chr8	48790345	48790345	C	T	Missense_Mutation	p.R1767Q	2
PRKDC	TGCT	chr8	48749779	48749779	T	A	Missense_Mutation		2
PRKDC	UCEC	chr8	48691059	48691059	G	A	Silent	p.S3907L	2
PRKDC	UCEC	chr8	48776025	48776025	T	G	Missense_Mutation	p.K1894N	2
PRKDC	LUAD	chr8	48866220	48866220	C	A	Missense_Mutation	p.L227F	2
PRKDC	STAD	chr8	48711778	48711778	A	G	Silent		2
PRKDC	ESCA	chr8	48733437	48733437	G	A	Missense_Mutation	p.S3059F	2
PRKDC	LUAD	chr8	48767902	48767902	T	C	Silent	p.R2213R	2
PRKDC	UCEC	chr8	48845728	48845728	G	T	Missense_Mutation	p.S543Y	2
PRKDC	ESCA	chr8	48776098	48776098	A	G	Missense_Mutation	p.M1870T	2
PRKDC	CESC	chr8	48776016	48776016	T	C	Silent		2
PRKDC	UCEC	chr8	48713457	48713457	G	A	Nonsense_Mutation	p.R3338*	2
PRKDC	LIHC	chr8	48866223	48866223	C	-	Frame_Shift_Del	p.G226fs	2
PRKDC	UCEC	chr8	48749008	48749008	G	A	Silent	p.A2614V	2
PRKDC	PAAD	chr8	48743248	48743248	T	C	Missense_Mutation		2
PRKDC	ESCA	chr8	48734226	48734226	G	T	Missense_Mutation	p.A3016D	2
PRKDC	ESCA	chr8	48744396	48744396	A	G	Silent		2
PRKDC	PAAD	chr8	48691183	48691183	A	C	Missense_Mutation	p.F3896C	2
PRKDC	TGCT	chr8	48842554	48842554	T	C	Silent		2
PRKDC	LIHC	chr8	48800123	48800123	A	-	Frame_Shift_Del	p.F1518fs	2
PRKDC	UCEC	chr8	48691358	48691358	C	T	Missense_Mutation	p.G3860D	2
PRKDC	UCEC	chr8	48777302	48777302	C	T	Missense_Mutation	p.G1795S	2
PRKDC	KIRP	chr8	48744423	48744423	G	T	Silent	p.L2738L	2
PRKDC	UCEC	chr8	48815248	48815248	C	T	Silent	p.E1050	2
PRKDC	LUAD	chr8	48772236	48772236	C	T	Missense_Mutation	p.G2047E	2
PRKDC	UCEC	chr8	48848299	48848299	A	G	Silent	p.S480	2
PRKDC	STAD	chr8	48701555	48701555	T	-	Frame_Shift_Del	p.N3604fs	2
PRKDC	LIHC	chr8	48701735	48701735	A	G	Missense_Mutation		2
PRKDC	PRAD	chr8	48691160	48691160	C	T	Missense_Mutation	p.A3904T	2
PRKDC	CESC	chr8	48761999	48761999	C	A	Missense_Mutation		2
PRKDC	UCEC	chr8	48713466	48713466	C	A	Nonsense_Mutation	p.G3335*	2
PRKDC	BLCA	chr8	48866199	48866199	G	T	Missense_Mutation	p.F234L	2
PRKDC	HNSC	chr8	48852134	48852134	G	A	Missense_Mutation	p.R364C	2
PRKDC	PAAD	chr8	48790367	48790367	A	C	Missense_Mutation		2
PRKDC	ESCA	chr8	48734271	48734271	T	C	Missense_Mutation	p.Y3001C	2
PRKDC	LIHC	chr8	48805813	48805813	C	G	Missense_Mutation		2
PRKDC	BLCA	chr8	48801778	48801778	C	T	Silent	p.L1358L	2
PRKDC	LIHC	chr8	48839881	48839881	G	-	Frame_Shift_Del	p.P764fs	2
PRKDC	SARC	chr8	48746783	48746783	C	T	Missense_Mutation	p.G2708E	2
PRKDC	UCEC	chr8	48694765	48694765	A	G	Missense_Mutation	p.L3815P	2
PRKDC	UCEC	chr8	48790402	48790402	G	T	Missense_Mutation	p.A1748E	2
PRKDC	BLCA	chr8	48716043	48716043	T	C	Splice_Site		2
PRKDC	KIRP	chr8	48826505	48826505	G	A	Nonsense_Mutation	p.R913*	2
PRKDC	UCEC	chr8	48817474	48817474	C	A	Missense_Mutation	p.K999N	2
PRKDC	HNSC	chr8	48842538	48842538	C	A	Nonsense_Mutation	p.E643*	2
PRKDC	UCEC	chr8	48848923	48848923	T	C	Missense_Mutation	p.Y423C	2
PRKDC	LGG	chr8	48744441	48744441	C	A	Missense_Mutation		2
PRKDC	LIHC	chr8	48794637	48794637	T	C	Missense_Mutation		2
PRKDC	PRAD	chr8	48739269	48739269	G	T	Missense_Mutation	p.R2910S	2
PRKDC	UCEC	chr8	48715964	48715964	G	T	Missense_Mutation	p.S3274R	2
PRKDC	UCEC	chr8	48752611	48752611	A	G	Missense_Mutation	p.Y2473H	2
PRKDC	TGCT	chr8	48826575	48826575	C	G	Missense_Mutation		2
PRKDC	LIHC	chr8	48855910	48855910	A	-	Frame_Shift_Del	p.F275fs	2
PRKDC	SARC	chr8	48801762	48801763	-	A	Frame_Shift_Ins	p.*Y1363fs	2
PRKDC	UCEC	chr8	48695146	48695146	G	A	Missense_Mutation	p.A3729V	2
PRKDC	UCEC	chr8	48794065	48794065	G	T	Missense_Mutation	p.S1659Y	2
PRKDC	BLCA	chr8	48815271	48815271	G	C	Missense_Mutation		2
PRKDC	KIRP	chr8	48809814	48809814	C	G	Missense_Mutation	p.V1169L	2
PRKDC	UCEC	chr8	48825009	48825009	C	T	Silent	p.T965	2
PRKDC	STAD	chr8	48691118	48691118	C	T	Missense_Mutation		2
PRKDC	UCEC	chr8	48848994	48848994	C	T	Silent	p.Q399	2
PRKDC	LGG	chr8	48706915	48706915	T	C	Missense_Mutation		2
PRKDC	LIHC	chr8	48715984	48715984	T	G	Silent		2
PRKDC	CESC	chr8	48869744	48869744	G	C	Missense_Mutation		2
PRKDC	UCEC	chr8	48715979	48715979	G	A	Silent	p.T3270M	2
PRKDC	ESCA	chr8	48827892	48827892	C	G	Silent		2
PRKDC	LIHC	chr8	48694762	48694762	A	-	Frame_Shift_Del	p.L3816fs	2
PRKDC	UCEC	chr8	48752648	48752648	G	A	Silent	p.S2461L	2
PRKDC	KIRC	chr8	48852194	48852194	G	A	Nonsense_Mutation	p.Q344*	2
PRKDC	ESCA	chr8	48691161	48691161	G	A	Silent		2
PRKDC	PAAD	chr8	48691183	48691183	A	C	Missense_Mutation		2
PRKDC	SARC	chr8	48801641	48801641	G	T	Missense_Mutation		2
PRKDC	ESCA	chr8	48739330	48739330	G	C	Missense_Mutation	p.I2889M	2
PRKDC	LIHC	chr8	48697806	48697806	A	C	Missense_Mutation		2
PRKDC	TGCT	chr8	48746932	48746932	C	G	Silent		2
PRKDC	LIHC	chr8	48869789	48869789	A	-	Frame_Shift_Del	p.L89fs	2
PRKDC	HNSC	chr8	48701554	48701555	-	-	Frame_Shift_Ins		2
PRKDC	UCEC	chr8	48697738	48697738	T	G	Missense_Mutation	p.K3680N	2
PRKDC	SKCM	chr8	48855781	48855781	G	A	Silent	p.S318S	2
PRKDC	UCEC	chr8	48798574	48798574	C	T	Silent	p.R1569Q	2
PRKDC	BLCA	chr8	48815271	48815271	G	C	Missense_Mutation	p.Q1043E	2
PRKDC	KIRP	chr8	48809814	48809814	C	G	Missense_Mutation		2
PRKDC	UCEC	chr8	48827897	48827897	G	T	Missense_Mutation	p.L870I	2
PRKDC	STAD	chr8	48849035	48849035	C	T	Missense_Mutation		2
PRKDC	LUAD	chr8	48790322	48790322	C	T	Missense_Mutation	p.E1775K	2
PRKDC	UCEC	chr8	48852195	48852195	C	A	Missense_Mutation	p.E343D	2
PRKDC	LIHC	chr8	48794060	48794060	T	C	Missense_Mutation		2
PRKDC	PRAD	chr8	48776073	48776073	C	A	Silent	p.V1878V	2
PRKDC	CESC	chr8	48740909	48740909	C	G	Splice_Site		2
PRKDC	UCEC	chr8	48716000	48716000	A	G	Silent	p.I3263T	2
PRKDC	LIHC	chr8	48696370	48696370	C	-	Splice_Site	p.G3702_splice	2
PRKDC	UCEC	chr8	48761741	48761741	C	A	Missense_Mutation	p.K2417N	2
PRKDC	KIRC	chr8	48690437	48690437	T	A	Splice_Site		2
PRKDC	LIHC	chr8	48839799	48839799	T	C	Missense_Mutation	p.I792V	2
PRKDC	SARC	chr8	48811051	48811051	G	T	Missense_Mutation		2
PRKDC	LGG	chr8	48715996	48715996	C	A	Nonsense_Mutation	p.E3264*	1
PRKDC	ESCA	chr8	48744396	48744396	A	G	Silent	p.V2747	1
PRKDC	LUSC	chr8	48719888	48719888	C	T	Splice_Site	p.R3185_splice	1
PRKDC	LIHC	chr8	48710835	48710835	C	A	Missense_Mutation		1
PRKDC	STAD	chr8	48824975	48824975	C	T	Missense_Mutation	p.D977N	1
PRKDC	PCPG	chr8	48686831	48686831	C	T	Missense_Mutation		1
PRKDC	TGCT	chr8	48746932	48746932	C	G	Silent	p.L2658L	1
PRKDC	BLCA	chr8	48691020	48691020	C	T	Splice_Site	p.Q3950Q	1
PRKDC	ESCA	chr8	48866215	48866215	G	C	Nonsense_Mutation		1
PRKDC	LIHC	chr8	48691624	48691624	T	-	Frame_Shift_Del	p.K3839fs	1
PRKDC	HNSC	chr8	48809798	48809798	G	C	Missense_Mutation		1
PRKDC	SARC	chr8	48733396	48733396	G	A	Nonsense_Mutation		1
PRKDC	LIHC	chr8	48815178	48815178	T	A	Nonsense_Mutation		1
PRKDC	SKCM	chr8	48801781	48801781	G	A	Silent	p.L1357L	1
PRKDC	BLCA	chr8	48772207	48772207	C	T	Missense_Mutation		1
PRKDC	BLCA	chr8	48719847	48719847	G	C	Missense_Mutation	p.L3199V	1
PRKDC	HNSC	chr8	48794645	48794645	A	G	Missense_Mutation	p.L1596S	1
PRKDC	SKCM	chr8	48713417	48713417	G	A	Silent	p.I3350I	1
PRKDC	LUAD	chr8	48845668	48845668	A	T	Nonsense_Mutation	p.L563*	1
PRKDC	KIRP	chr8	48744423	48744423	G	T	Silent		1
PRKDC	STAD	chr8	48855837	48855837	A	G	Missense_Mutation	p.W300R	1
PRKDC	LUSC	chr8	48824970	48824970	C	A	Missense_Mutation	p.Q978_splice	1
PRKDC	BLCA	chr8	48761858	48761858	C	A	Missense_Mutation		1
PRKDC	BLCA	chr8	48801695	48801695	C	A	Missense_Mutation	p.G1386V	1
PRKDC	HNSC	chr8	48815311	48815311	A	G	Silent	p.C1029C	1
PRKDC	LUAD	chr8	48801713	48801713	C	A	Missense_Mutation	p.S1380I	1
PRKDC	HNSC	chr8	48746771	48746771	T	C	Missense_Mutation	p.D2713G	1
PRKDC	LUAD	chr8	48746958	48746958	C	T	Splice_Site		1
PRKDC	STAD	chr8	48690324	48690324	G	A	Missense_Mutation	p.R3989W	1
PRKDC	CESC	chr8	48694968	48694968	C	T	Silent	p.R3788	1
PRKDC	LGG	chr8	48715996	48715996	C	A	Nonsense_Mutation		1
PRKDC	ESCA	chr8	48866998	48866998	C	T	Silent	p.Q136	1
PRKDC	OV	chr8	48841678	48841678	C	T	Missense_Mutation	p.A705T	1
PRKDC	LIHC	chr8	48792161	48792176	TCCTCCAGACTGCCTC	-	Frame_Shift_Del		1
PRKDC	STAD	chr8	48772185	48772185	C	T	Missense_Mutation	p.R2065H	1
PRKDC	PRAD	chr8	48771540	48771540	C	A	Missense_Mutation	p.R2071L	1
PRKDC	THYM	chr8	48733480	48733480	G	T	Missense_Mutation		1
PRKDC	BLCA	chr8	48846651	48846651	C	G	Splice_Site	p.G500_splice	1
PRKDC	GBM	chr8	48830872	48830872	A	G	Silent		1
PRKDC	UCEC	chr8	48802945	48802945	G	T	Missense_Mutation	p.T1314N	1
PRKDC	SKCM	chr8	48815190	48815190	G	A	Missense_Mutation	p.P1070S	1
PRKDC	LUAD	chr8	48772321	48772321	C	T	Splice_Site		1
PRKDC	ESCA	chr8	48694817	48694817	T	G	Splice_Site	.	1
PRKDC	HNSC	chr8	48842559	48842559	C	G	Missense_Mutation		1
PRKDC	LIHC	chr8	48772210	48772210	G	-	Frame_Shift_Del	p.Q2056fs	1
PRKDC	UCEC	chr8	48749870	48749870	A	-	Frame_Shift_Del	p.L2554fs	1
PRKDC	SKCM	chr8	48744474	48744474	C	T	Silent	p.R2721R	1
PRKDC	BLCA	chr8	48744473	48744473	T	G	Missense_Mutation		1
PRKDC	HNSC	chr8	48776002	48776002	G	A	Missense_Mutation	p.S1902L	1
PRKDC	LUAD	chr8	48730024	48730024	T	C	Missense_Mutation	p.I3181V	1
PRKDC	KIRC	chr8	48694798	48694798	C	T	Nonsense_Mutation	p.W3804*	1
PRKDC	SKCM	chr8	48869985	48869985	T	A	Missense_Mutation	p.Q54L	1
PRKDC	LUAD	chr8	48689479	48689479	T	A	Missense_Mutation	p.K4036N	1
PRKDC	STAD	chr8	48852211	48852211	A	G	Missense_Mutation	p.L338P	1
PRKDC	COAD	chr8	48761938	48761938	A	G	Splice_Site	.	1
PRKDC	LIHC	chr8	48744430	48744430	T	C	Missense_Mutation		1
PRKDC	ESCA	chr8	48734226	48734226	G	T	Missense_Mutation		1
PRKDC	STAD	chr8	48733370	48733370	G	A	Silent	p.Y3082Y	1
PRKDC	LIHC	chr8	48697806	48697806	A	C	Missense_Mutation	p.F3658V	1
PRKDC	STAD	chr8	48701555	48701556	-	T	Frame_Shift_Ins	p.N3604fs	1
PRKDC	BLCA	chr8	48777246	48777246	G	A	Silent	p.F1813F	1
PRKDC	LGG	chr8	48731985	48731985	G	T	Missense_Mutation	p.F3140L	1
PRKDC	ESCA	chr8	48751732	48751733	-	A	Frame_Shift_Ins	p.L2509fs	1
PRKDC	LUSC	chr8	48772318	48772318	C	A	Missense_Mutation	p.G2020C	1
PRKDC	LIHC	chr8	48824971	48824971	T	A	Missense_Mutation		1
PRKDC	STAD	chr8	48701752	48701752	T	C	Missense_Mutation	p.N3573S	1
PRKDC	PRAD	chr8	48811034	48811034	G	A	Missense_Mutation	p.P1154S	1
PRKDC	TGCT	chr8	48749779	48749779	T	A	Missense_Mutation	p.E2584D	1
PRKDC	BLCA	chr8	48739356	48739356	C	T	Missense_Mutation	p.A2881T	1
PRKDC	GBM	chr8	48772255	48772255	G	A	Nonsense_Mutation	p.Q2041*	1
PRKDC	LIHC	chr8	48694789	48694789	T	-	Frame_Shift_Del	p.N3807fs	1
PRKDC	HNSC	chr8	48826618	48826618	G	A	Missense_Mutation		1
PRKDC	SARC	chr8	48776138	48776138	G	T	Missense_Mutation		1
PRKDC	LUAD	chr8	48826536	48826536	T	A	Missense_Mutation	p.K902N	1
PRKDC	SKCM	chr8	48801780	48801780	G	A	Silent	p.L1358L	1
PRKDC	BLCA	chr8	48719725	48719725	C	T	Missense_Mutation		1
PRKDC	BLCA	chr8	48690357	48690357	C	T	Missense_Mutation	p.G3977S	1
PRKDC	HNSC	chr8	48826618	48826618	G	A	Missense_Mutation	p.S875F	1
PRKDC	SKCM	chr8	48749903	48749903	G	A	Missense_Mutation	p.S2543F	1
PRKDC	LUAD	chr8	48826496	48826496	C	G	Missense_Mutation	p.E916Q	1
PRKDC	KIRP	chr8	48826505	48826505	G	A	Nonsense_Mutation		1
PRKDC	STAD	chr8	48711778	48711778	A	G	Silent	p.N3429N	1
PRKDC	LUSC	chr8	48855900	48855900	C	T	Missense_Mutation	p.A279T	1
PRKDC	BLCA	chr8	48694764	48694764	A	G	Silent		1
PRKDC	HNSC	chr8	48697804	48697804	G	A	Silent	p.F3658F	1
PRKDC	LUAD	chr8	48689479	48689479	T	A	Missense_Mutation	p.K4035N	1
PRKDC	HNSC	chr8	48715931	48715931	G	A	Silent	p.C3286C	1
PRKDC	SKCM	chr8	48752648	48752648	G	A	Silent	p.F2460F	1
PRKDC	LUAD	chr8	48715952	48715952	G	C	Missense_Mutation	p.S3278R	1
PRKDC	STAD	chr8	48706944	48706944	G	A	Missense_Mutation	p.P3526L	1
PRKDC	CESC	chr8	48736444	48736444	G	C	Missense_Mutation	p.S2965C	1
PRKDC	LGG	chr8	48749833	48749833	G	A	Silent		1
PRKDC	OV	chr8	48767881	48767881	T	-	Frame_Shift_Del	p.K2220fs	1
PRKDC	LIHC	chr8	48707064	48707064	T	A	Splice_Site	.	1
PRKDC	STAD	chr8	48743175	48743175	G	A	Silent	p.A2796A	1
PRKDC	SARC	chr8	48749803	48749803	G	T	Missense_Mutation		1
PRKDC	THYM	chr8	48805844	48805844	G	A	Silent		1
PRKDC	BLCA	chr8	48749802	48749802	C	T	Missense_Mutation	p.E2578K	1
PRKDC	CESC	chr8	48855777	48855777	G	C	Missense_Mutation		1
PRKDC	GBM	chr8	48846577	48846577	T	C	Missense_Mutation		1
PRKDC	HNSC	chr8	48777319	48777319	G	T	Nonsense_Mutation	p.S1789*	1
PRKDC	UCEC	chr8	48855904	48855904	C	T	Silent	p.L277L	1
PRKDC	SKCM	chr8	48794651	48794651	G	A	Missense_Mutation	p.A1594V	1
PRKDC	LUAD	chr8	48689545	48689545	C	G	Splice_Site		1
PRKDC	BLCA	chr8	48802890	48802890	G	T	Missense_Mutation	p.S1332R	1
PRKDC	ESCA	chr8	48866998	48866998	C	T	Silent	p.Q136Q	1
PRKDC	HNSC	chr8	48839755	48839755	T	A	Silent		1
PRKDC	SARC	chr8	48801641	48801641	G	T	Missense_Mutation	p.A1404D	1
PRKDC	LIHC	chr8	48774943	48774943	T	-	Frame_Shift_Del	p.K1969fs	1
PRKDC	UCEC	chr8	48691607	48691608	-	T	Frame_Shift_Ins	p.M3845fs	1
PRKDC	SKCM	chr8	48839792	48839792	G	A	Missense_Mutation	p.P794L	1
PRKDC	BLCA	chr8	48801778	48801778	C	T	Silent		1
PRKDC	LUAD	chr8	48762047	48762047	C	G	Silent	p.L2340L	1
PRKDC	KIRC	chr8	48730110	48730110	G	T	Missense_Mutation	p.S3152Y	1
PRKDC	SKCM	chr8	48848431	48848431	C	A	Missense_Mutation	p.E436D	1
PRKDC	LUAD	chr8	48855770	48855770	T	A	Missense_Mutation	p.Q322L	1
PRKDC	STAD	chr8	48762039	48762039	A	G	Missense_Mutation	p.L2344P	1
PRKDC	COAD	chr8	48765346	48765346	C	T	Splice_Site	.	1
PRKDC	STAD	chr8	48697726	48697726	G	T	Silent	p.P3685P	1
PRKDC	LIHC	chr8	48690356	48690356	C	G	Missense_Mutation	p.G3977A	1
PRKDC	STAD	chr8	48689518	48689519	-	T	Frame_Shift_Ins	p.K4022fs	1
PRKDC	LGG	chr8	48715981	48715981	C	A	Missense_Mutation	p.D3269Y	1
PRKDC	ESCA	chr8	48767818	48767818	G	A	Silent	p.V2241	1
PRKDC	LUSC	chr8	48869797	48869797	T	C	Silent	p.L86L	1
PRKDC	LIHC	chr8	48746901	48746901	G	A	Missense_Mutation		1
PRKDC	STAD	chr8	48732055	48732055	T	C	Missense_Mutation	p.D3118G	1
PRKDC	PRAD	chr8	48798701	48798701	C	T	Missense_Mutation	p.R1526H	1
PRKDC	THCA	chr8	48749054	48749054	C	T	Missense_Mutation		1
PRKDC	BLCA	chr8	48746857	48746857	C	T	Silent	p.R2683R	1
PRKDC	GBM	chr8	48869810	48869810	C	T	Missense_Mutation	p.R82K	1
PRKDC	LIHC	chr8	48732022	48732022	A	-	Frame_Shift_Del	p.L3128fs	1
PRKDC	HNSC	chr8	48706909	48706909	C	T	Missense_Mutation		1
PRKDC	SARC	chr8	48739410	48739410	G	A	Nonsense_Mutation	p.Q2863*	1
PRKDC	LUAD	chr8	48777168	48777168	G	A	Silent	p.F1839F	1
PRKDC	SKCM	chr8	48802882	48802882	G	A	Missense_Mutation	p.T1335I	1
PRKDC	BLCA	chr8	48761978	48761978	C	A	Missense_Mutation		1
PRKDC	BLCA	chr8	48772207	48772207	C	T	Missense_Mutation	p.D2057N	1
PRKDC	SKCM	chr8	48744479	48744479	C	T	Missense_Mutation	p.G2720S	1
PRKDC	LUAD	chr8	48801591	48801591	T	C	Missense_Mutation	p.K1421E	1
PRKDC	KIRP	chr8	48800126	48800126	G	T	Silent		1
PRKDC	STAD	chr8	48746805	48746805	T	C	Missense_Mutation	p.K2701E	1
PRKDC	BLCA	chr8	48848390	48848390	C	A	Missense_Mutation		1
PRKDC	BLCA	chr8	48740729	48740729	C	T	Splice_Site	p.Q2858Q	1
PRKDC	HNSC	chr8	48839755	48839755	T	A	Splice_Site	p.S806_splice	1
PRKDC	LUAD	chr8	48746778	48746778	C	T	Missense_Mutation	p.E2710K	1
PRKDC	HNSC	chr8	48798673	48798673	C	T	Silent	p.A1536A	1
PRKDC	LUAD	chr8	48711843	48711843	C	A	Missense_Mutation	p.V3409L	1
PRKDC	STAD	chr8	48809839	48809839	G	A	Silent	p.S1160S	1
PRKDC	CESC	chr8	48740909	48740909	C	G	Splice_Site	e63-1	1
PRKDC	LGG	chr8	48761853	48761853	G	A	Missense_Mutation		1
PRKDC	OV	chr8	48734191	48734191	T	C	Missense_Mutation	p.K3028E	1
PRKDC	LIHC	chr8	48856412	48856412	C	A	Splice_Site	.	1
PRKDC	STAD	chr8	48732013	48732013	A	G	Missense_Mutation	p.V3132A	1
PRKDC	SARC	chr8	48746783	48746783	C	T	Missense_Mutation		1
PRKDC	BLCA	chr8	48805803	48805803	G	A	Silent	p.F1248F	1
PRKDC	GBM	chr8	48691111	48691111	C	A	Missense_Mutation		1
PRKDC	SARC	chr8	48802974	48802974	G	T	Missense_Mutation		1
PRKDC	LIHC	chr8	48869968	48869968	A	-	Frame_Shift_Del	p.S60fs	1
PRKDC	HNSC	chr8	48815268	48815268	T	C	Missense_Mutation	p.I1044V	1
PRKDC	UCEC	chr8	48802882	48802882	G	T	Missense_Mutation	p.T1335N	1
PRKDC	SKCM	chr8	48802901	48802901	A	G	Missense_Mutation	p.Y1329H	1
PRKDC	BLCA	chr8	48826512	48826512	G	A	Silent	p.F910F	1
PRKDC	HNSC	chr8	48697804	48697804	G	A	Silent		1
PRKDC	LIHC	chr8	48777257	48777257	G	-	Frame_Shift_Del	p.R1810fs	1
PRKDC	SKCM	chr8	48691182	48691182	G	A	Silent	p.F3896F	1
PRKDC	BLCA	chr8	48739311	48739311	G	C	Missense_Mutation		1
PRKDC	HNSC	chr8	48706964	48706964	T	A	Missense_Mutation	p.E3518D	1
PRKDC	LUAD	chr8	48690420	48690420	C	A	Nonsense_Mutation	p.E3956*	1
PRKDC	KIRC	chr8	48762023	48762023	C	A	Missense_Mutation	p.L2348F	1
PRKDC	SKCM	chr8	48794604	48794604	G	T	Missense_Mutation	p.Q1610K	1
PRKDC	LUAD	chr8	48817449	48817449	C	A	Missense_Mutation	p.A1008S	1
PRKDC	STAD	chr8	48809800	48809800	T	C	Silent	p.L1173L	1
PRKDC	COAD	chr8	48842411	48842411	A	G	Splice_Site	.	1
PRKDC	LUSC	chr8	48706936	48706936	T	C	Missense_Mutation	p.I3528V	1
PRKDC	LIHC	chr8	48869825	48869825	T	C	Splice_Site		1
PRKDC	ESCA	chr8	48790371	48790373	CAA	-	In_Frame_Del		1
PRKDC	STAD	chr8	48746911	48746911	C	T	Silent	p.P2666P	1
PRKDC	LIHC	chr8	48701573	48701573	G	A	Missense_Mutation	p.T3598I	1
PRKDC	STAD	chr8	48749058	48749058	G	A	Nonsense_Mutation		1
PRKDC	LGG	chr8	48771461	48771461	C	T	Silent	p.T2097T	1
PRKDC	ESCA	chr8	48773474	48773474	G	T	Missense_Mutation	p.A2014E	1
PRKDC	LIHC	chr8	48766776	48766776	C	A	Splice_Site		1
PRKDC	STAD	chr8	48774943	48774943	T	C	Silent	p.K1970K	1
PRKDC	PRAD	chr8	48761940	48761940	C	A	Splice_Site	p.R2376_splice	1
PRKDC	THCA	chr8	48771540	48771540	C	A	Missense_Mutation		1
PRKDC	BLCA	chr8	48734210	48734210	C	G	Missense_Mutation	p.E3021D	1
PRKDC	LIHC	chr8	48767862	48767862	T	-	Frame_Shift_Del	p.R2227fs	1
PRKDC	HNSC	chr8	48761984	48761984	C	T	Silent		1
PRKDC	SARC	chr8	48845610	48845610	T	G	Silent	p.T582	1
PRKDC	LUAD	chr8	48711843	48711843	C	A	Missense_Mutation	p.V3408L	1
PRKDC	SKCM	chr8	48740752	48740752	G	A	Missense_Mutation	p.P2851S	1
PRKDC	BLCA	chr8	48794547	48794547	C	T	Missense_Mutation		1
PRKDC	BLCA	chr8	48719725	48719725	C	T	Missense_Mutation	p.M3239I	1
PRKDC	SKCM	chr8	48749810	48749810	G	A	Missense_Mutation	p.P2574L	1
PRKDC	LUAD	chr8	48772259	48772259	C	G	Missense_Mutation	p.M2039I	1
PRKDC	KIRP	chr8	48775068	48775068	C	A	Missense_Mutation		1
PRKDC	STAD	chr8	48749058	48749058	G	A	Nonsense_Mutation	p.R2597*	1
PRKDC	BLCA	chr8	48866199	48866199	G	T	Missense_Mutation		1
PRKDC	BLCA	chr8	48761858	48761858	C	A	Missense_Mutation	p.M2378I	1
PRKDC	LUAD	chr8	48790311	48790311	T	G	Missense_Mutation	p.Q1778H	1
PRKDC	HNSC	chr8	48794645	48794645	A	G	Missense_Mutation	p.L1597S	1
PRKDC	LUAD	chr8	48711844	48711844	C	G	Silent	p.G3408G	1
PRKDC	STAD	chr8	48848299	48848299	A	G	Silent	p.S480S	1
PRKDC	CESC	chr8	48751794	48751794	C	T	Missense_Mutation	p.E2489K	1
PRKDC	LGG	chr8	48766717	48766717	T	C	Missense_Mutation		1
PRKDC	ESCA	chr8	48751732	48751733	-	-	Frame_Shift_Ins		1
PRKDC	OV	chr8	48811097	48811097	G	C	Missense_Mutation	p.H1133D	1
PRKDC	LIHC	chr8	48767935	48767935	C	T	Splice_Site	.	1
PRKDC	STAD	chr8	48815346	48815346	C	T	Missense_Mutation	p.V1018M	1
PRKDC	SARC	chr8	48694735	48694735	G	T	Missense_Mutation		1
PRKDC	THYM	chr8	48743185	48743185	G	T	Missense_Mutation		1
PRKDC	BLCA	chr8	48690396	48690396	G	A	Missense_Mutation	p.R3965C	1
PRKDC	GBM	chr8	48701499	48701499	C	A	Missense_Mutation		1
PRKDC	SARC	chr8	48701570	48701570	G	-	Frame_Shift_Del		1
PRKDC	LIHC	chr8	48689466	48689466	G	-	Frame_Shift_Del	p.R4040fs	1
PRKDC	SKCM	chr8	48769844	48769844	G	C	Missense_Mutation	p.A2160G	1
PRKDC	BLCA	chr8	48689514	48689514	C	G	Missense_Mutation	p.G4024R	1
PRKDC	ESCA	chr8	48694970	48694970	T	C	Missense_Mutation	p.R3788G	1
PRKDC	HNSC	chr8	48746771	48746771	T	C	Missense_Mutation		1
PRKDC	SARC	chr8	48691220	48691220	G	T	Splice_Site	p.R3884_splice	1
PRKDC	LIHC	chr8	48794522	48794522	G	-	Frame_Shift_Del	p.P1637fs	1
PRKDC	SKCM	chr8	48761735	48761735	G	A	Silent	p.F2419F	1
PRKDC	ACC	chr8	48790325	48790325	C	A	Nonsense_Mutation	p.E1774*	1
PRKDC	BLCA	chr8	48719764	48719764	G	A	Silent		1
PRKDC	HNSC	chr8	48809798	48809798	G	C	Missense_Mutation	p.A1174G	1
PRKDC	LUAD	chr8	48701799	48701799	C	A	Splice_Site	p.R3556_splice	1
PRKDC	KIRC	chr8	48762043	48762043	C	T	Missense_Mutation	p.E2342K	1
PRKDC	STAD	chr8	48746799	48746799	T	-	Frame_Shift_Del		1
PRKDC	LUAD	chr8	48690420	48690420	C	A	Nonsense_Mutation	p.E3957*	1
PRKDC	STAD	chr8	48743232	48743232	G	A	Silent	p.H2777H	1
PRKDC	ESCA	chr8	48691161	48691161	G	A	Silent	p.F3903	1
PRKDC	LUSC	chr8	48711773	48711773	G	C	Nonsense_Mutation	p.S3431*	1
PRKDC	LIHC	chr8	48751726	48751726	A	G	Silent		1
PRKDC	ESCA	chr8	48767818	48767818	G	A	Silent		1
PRKDC	STAD	chr8	48701529	48701529	A	G	Missense_Mutation	p.Y3614H	1
PRKDC	LIHC	chr8	48701735	48701735	A	G	Missense_Mutation	p.S3578P	1
PRKDC	STAD	chr8	48866410	48866410	G	T	Missense_Mutation		1
PRKDC	CESC	chr8	48761816	48761816	C	G	Missense_Mutation	p.L2392F	1
PRKDC	LGG	chr8	48761853	48761853	G	A	Missense_Mutation	p.A2380V	1
PRKDC	MESO	chr8	48744470	48744470	C	T	Missense_Mutation		1
PRKDC	LIHC	chr8	48855901	48855901	A	G	Silent		1
PRKDC	STAD	chr8	48817531	48817531	T	C	Silent	p.T980T	1
PRKDC	THCA	chr8	48686858	48686858	T	C	Missense_Mutation	p.N4087S	1
PRKDC	BLCA	chr8	48734253	48734253	C	T	Nonsense_Mutation	p.W3007*	1
PRKDC	GBM	chr8	48805878	48805878	G	A	Missense_Mutation	p.T1223I	1
PRKDC	LIHC	chr8	48774669	48774669	T	-	Frame_Shift_Del	p.N1979fs	1
PRKDC	HNSC	chr8	48736553	48736553	A	G	Missense_Mutation		1
PRKDC	SARC	chr8	48866457	48866457	G	A	Silent	p.L177	1
PRKDC	LUAD	chr8	48748977	48748977	G	A	Missense_Mutation	p.L2624F	1
PRKDC	SKCM	chr8	48792099	48792099	G	A	Missense_Mutation	p.P1729S	1
PRKDC	BLCA	chr8	48817520	48817520	T	C	Missense_Mutation		1
PRKDC	BLCA	chr8	48794547	48794547	C	T	Missense_Mutation	p.D1629N	1
PRKDC	HNSC	chr8	48719860	48719860	C	G	Missense_Mutation	p.E3195D	1
PRKDC	SKCM	chr8	48805886	48805886	G	A	Silent	p.L1220L	1
PRKDC	LUAD	chr8	48845627	48845627	C	T	Missense_Mutation	p.E577K	1
PRKDC	LGG	chr8	48792204	48792204	G	C	Missense_Mutation	p.L1694V	1
PRKDC	STAD	chr8	48776134	48776134	T	C	Missense_Mutation	p.N1858S	1
PRKDC	BLCA	chr8	48772246	48772246	A	T	Missense_Mutation		1
PRKDC	BLCA	chr8	48694764	48694764	A	G	Silent	p.L3815L	1
PRKDC	HNSC	chr8	48746868	48746868	C	T	Missense_Mutation	p.A2680T	1
PRKDC	LUAD	chr8	48771477	48771477	C	G	Missense_Mutation	p.C2092S	1
PRKDC	HNSC	chr8	48733339	48733339	G	A	Nonsense_Mutation	p.Q3093*	1
PRKDC	SKCM	chr8	48697753	48697753	G	A	Silent	p.P3675P	1
PRKDC	LUAD	chr8	48689545	48689545	C	G	Splice_Site	p.N4015_splice	1
PRKDC	UCS	chr8	48801143	48801143	G	A	Missense_Mutation		1
PRKDC	STAD	chr8	48846583	48846583	G	T	Missense_Mutation	p.P522H	1
PRKDC	CESC	chr8	48776016	48776016	T	C	Silent	p.Q1897	1
PRKDC	LGG	chr8	48771461	48771461	C	T	Silent		1
PRKDC	OV	chr8	48746759	48746759	T	C	Missense_Mutation	p.K2716R	1
PRKDC	LIHC	chr8	48846651	48846651	C	T	Splice_Site	.	1
PRKDC	STAD	chr8	48842451	48842451	T	C	Missense_Mutation	p.I672V	1
PRKDC	SARC	chr8	48848376	48848376	G	T	Missense_Mutation		1
PRKDC	THYM	chr8	48805844	48805844	G	A	Silent	p.G1234G	1
PRKDC	BLCA	chr8	48711931	48711931	C	T	Silent	p.Q3379Q	1
PRKDC	GBM	chr8	48773468	48773468	C	A	Missense_Mutation		1
PRKDC	LIHC	chr8	48697773	48697773	T	-	Frame_Shift_Del	p.M3669fs	1
PRKDC	HNSC	chr8	48761721	48761721	C	G	Missense_Mutation	p.R2424T	1
PRKDC	SKCM	chr8	48801704	48801704	A	T	Missense_Mutation	p.F1383Y	1
PRKDC	BLCA	chr8	48748973	48748973	G	A	Missense_Mutation	p.S2625L	1
PRKDC	ESCA	chr8	48744396	48744396	A	G	Silent	p.V2747V	1
PRKDC	HNSC	chr8	48715931	48715931	G	A	Silent		1
PRKDC	SARC	chr8	48690394	48690394	G	T	Silent	p.R3964R	1
PRKDC	LIHC	chr8	48825049	48825049	C	-	Frame_Shift_Del	p.G952fs	1
PRKDC	SKCM	chr8	48746878	48746878	G	A	Silent	p.S2676S	1
PRKDC	ACC	chr8	48801138	48801138	C	A	Missense_Mutation	p.V1451L	1
PRKDC	BLCA	chr8	48746857	48746857	C	T	Silent		1
PRKDC	LUAD	chr8	48719705	48719705	C	A	Missense_Mutation	p.R3246L	1
PRKDC	KIRC	chr8	48767813	48767813	C	T	Missense_Mutation	p.C2243Y	1
PRKDC	LUAD	chr8	48762047	48762047	C	G	Silent	p.L2341L	1
PRKDC	STAD	chr8	48769854	48769854	G	A	Missense_Mutation	p.R2158C	1
PRKDC	ESCA	chr8	48694817	48694817	T	G	Splice_Site	e81-2	1
PRKDC	LUSC	chr8	48719804	48719804	G	T	Missense_Mutation	p.P3213H	1
PRKDC	STAD	chr8	48845642	48845642	C	T	Missense_Mutation	p.V572I	1
PRKDC	STAD	chr8	48855837	48855837	A	G	Missense_Mutation		1
PRKDC	CESC	chr8	48751794	48751794	C	T	Missense_Mutation		1
PRKDC	LGG	chr8	48766717	48766717	T	C	Missense_Mutation	p.I2273V	1
PRKDC	MESO	chr8	48798614	48798614	C	A	Missense_Mutation		1
PRKDC	STAD	chr8	48825013	48825013	C	T	Missense_Mutation	p.R964Q	1
PRKDC	PRAD	chr8	48690415	48690415	C	A	Missense_Mutation	p.L3957F	1
PRKDC	THCA	chr8	48749054	48749054	C	T	Missense_Mutation	p.S2598N	1
PRKDC	BLCA	chr8	48734323	48734323	C	T	Missense_Mutation	p.E2984K	1
PRKDC	GBM	chr8	48805733	48805733	C	A	Missense_Mutation		1
PRKDC	LIHC	chr8	48776024	48776024	T	-	Frame_Shift_Del	p.I1895fs	1
PRKDC	HNSC	chr8	48815311	48815311	A	G	Silent		1
PRKDC	SARC	chr8	48801762	48801763	-	A	Frame_Shift_Ins	p.N1363fs	1
PRKDC	LUAD	chr8	48733455	48733455	T	G	Missense_Mutation	p.Q3053P	1
PRKDC	SKCM	chr8	48813002	48813002	A	G	Missense_Mutation	p.F1099L	1
PRKDC	BLCA	chr8	48740849	48740849	C	T	Silent		1
PRKDC	HNSC	chr8	48777319	48777319	G	T	Nonsense_Mutation	p.S1790*	1
PRKDC	SKCM	chr8	48697730	48697730	G	A	Missense_Mutation	p.S3683L	1
PRKDC	LUAD	chr8	48826610	48826610	C	A	Nonsense_Mutation	p.E878*	1
PRKDC	LGG	chr8	48706915	48706915	T	C	Missense_Mutation	p.S3535G	1
PRKDC	STAD	chr8	48849035	48849035	C	T	Missense_Mutation	p.V386I	1
PRKDC	UCEC	chr8	48749910	48749910	G	C	Missense_Mutation	p.L2541V	1
PRKDC	SKCM	chr8	48776009	48776009	G	A	Missense_Mutation	p.H1900Y	1
PRKDC	BLCA	chr8	48866272	48866272	G	A	Missense_Mutation		1
PRKDC	BLCA	chr8	48803019	48803019	A	C	Silent	p.L1289L	1
PRKDC	HNSC	chr8	48842559	48842559	C	G	Missense_Mutation	p.E636Q	1
PRKDC	LUAD	chr8	48798590	48798590	G	C	Nonsense_Mutation	p.S1563*	1
PRKDC	HNSC	chr8	48761806	48761807	AG	-	Frame_Shift_Del	p.L2396fs	1
PRKDC	SKCM	chr8	48744443	48744443	T	A	Missense_Mutation	p.M2732L	1
PRKDC	LUAD	chr8	48710830	48710830	G	C	Missense_Mutation	p.P3476A	1
PRKDC	STAD	chr8	48689516	48689516	C	T	Missense_Mutation	p.G4024E	1
PRKDC	CESC	chr8	48777246	48777246	G	A	Silent	p.F1813	1
PRKDC	LGG	chr8	48826496	48826496	C	A	Nonsense_Mutation		1
PRKDC	LIHC	chr8	48746959	48746959	T	A	Splice_Site	.	1
PRKDC	STAD	chr8	48746918	48746918	G	A	Missense_Mutation	p.T2664I	1
PRKDC	SARC	chr8	48772214	48772214	G	T	Missense_Mutation		1
PRKDC	BLCA	chr8	48801695	48801695	C	A	Missense_Mutation	p.G1387V	1
PRKDC	LIHC	chr8	48794637	48794637	T	C	Missense_Mutation	p.M1599V	1
PRKDC	HNSC	chr8	48719860	48719860	C	G	Missense_Mutation		1
PRKDC	SARC	chr8	48690394	48690394	G	T	Silent		1
PRKDC	LIHC	chr8	48798650	48798650	C	-	Frame_Shift_Del	p.G1543fs	1
PRKDC	LUSC	chr8	48815131	48815131	G	C	Missense_Mutation	p.F1089L	1
PRKDC	STAD	chr8	48852128	48852128	A	G	Missense_Mutation	p.Y366H	1
PRKDC	BLCA	chr8	48809834	48809834	G	C	Nonsense_Mutation	p.S1162*	1
PRKDC	ESCA	chr8	48827892	48827892	C	G	Silent	p.L871L	1
PRKDC	HNSC	chr8	48845609	48845609	G	C	Missense_Mutation		1
PRKDC	SARC	chr8	48766703	48766703	G	T	Silent	p.G2277G	1
PRKDC	LIHC	chr8	48852188	48852188	A	-	Frame_Shift_Del	p.Y346fs	1
PRKDC	SKCM	chr8	48840393	48840393	G	A	Missense_Mutation	p.L733F	1
PRKDC	ACC	chr8	48689404	48689404	C	T	Splice_Site		1
PRKDC	BLCA	chr8	48734210	48734210	C	G	Missense_Mutation		1
PRKDC	HNSC	chr8	48697683	48697683	C	A	Nonsense_Mutation	p.E3699*	1
PRKDC	KIRC	chr8	48794597	48794597	T	C	Missense_Mutation	p.H1612R	1
PRKDC	LUAD	chr8	48719705	48719705	C	A	Missense_Mutation	p.R3247L	1
PRKDC	STAD	chr8	48794568	48794568	G	T	Missense_Mutation	p.L1623M	1
PRKDC	HNSC	chr8	48697813	48697813	G	A	Silent	p.L3656L	1
PRKDC	SKCM	chr8	48751729	48751729	G	A	Silent	p.I2510I	1
PRKDC	LUAD	chr8	48719862	48719862	C	T	Missense_Mutation	p.E3194K	1
PRKDC	STAD	chr8	48691118	48691118	C	T	Missense_Mutation	p.G3918R	1
PRKDC	CESC	chr8	48842522	48842522	G	C	Nonsense_Mutation		1
PRKDC	LGG	chr8	48826496	48826496	C	A	Nonsense_Mutation	p.E916*	1
PRKDC	MESO	chr8	48839828	48839828	C	A	Missense_Mutation		1
PRKDC	LIHC	chr8	48701573	48701573	G	A	Missense_Mutation		1
PRKDC	STAD	chr8	48744483	48744483	C	T	Silent	p.A2719A	1
PRKDC	PRAD	chr8	48801155	48801155	C	T	Missense_Mutation	p.S1445N	1
PRKDC	THCA	chr8	48798637	48798637	G	A	Silent	p.G1547G	1
PRKDC	GBM	chr8	48805878	48805878	G	A	Missense_Mutation		1
PRKDC	LIHC	chr8	48794481	48794481	T	-	Frame_Shift_Del	p.I1651fs	1
PRKDC	HNSC	chr8	48798592	48798592	G	C	Missense_Mutation		1
PRKDC	SKCM	chr8	48769852	48769852	G	A	Silent	p.R2157R	1
PRKDC	LUAD	chr8	48711844	48711844	C	G	Silent	p.G3407G	1
PRKDC	SKCM	chr8	48736523	48736523	G	A	Missense_Mutation	p.R2939C	1
PRKDC	BLCA	chr8	48805803	48805803	G	A	Silent		1
PRKDC	BLCA	chr8	48749802	48749802	C	T	Missense_Mutation	p.E2577K	1
PRKDC	LIHC	chr8	48715984	48715984	T	G	Silent	p.R3268R	1
PRKDC	HNSC	chr8	48697813	48697813	G	A	Silent		1
PRKDC	SARC	chr8	48739287	48739287	G	T	Missense_Mutation		1
PRKDC	HNSC	chr8	48761984	48761984	C	T	Silent	p.V2361V	1
PRKDC	UCEC	chr8	48736456	48736456	C	A	Missense_Mutation	p.R2961I	1
PRKDC	SKCM	chr8	48868468	48868468	T	C	Missense_Mutation	p.K122R	1
PRKDC	BLCA	chr8	48848390	48848390	C	A	Missense_Mutation	p.S450I	1
PRKDC	HNSC	chr8	48713402	48713402	A	T	Silent	p.A3355A	1
PRKDC	LUAD	chr8	48777256	48777256	C	A	Missense_Mutation	p.R1810L	1
PRKDC	HNSC	chr8	48701554	48701555	-	T	Frame_Shift_Ins	p.N3605fs	1
PRKDC	SKCM	chr8	48749816	48749816	G	A	Missense_Mutation	p.P2572L	1
PRKDC	LUAD	chr8	48767902	48767902	T	C	Silent	p.R2214R	1
PRKDC	STAD	chr8	48825009	48825009	C	T	Silent	p.T965T	1
PRKDC	CESC	chr8	48792096	48792096	G	A	Missense_Mutation	p.P1730S	1
PRKDC	LGG	chr8	48694979	48694979	G	T	Missense_Mutation		1
PRKDC	LIHC	chr8	48774689	48774689	C	A	Splice_Site	.	1
PRKDC	STAD	chr8	48777241	48777241	C	T	Missense_Mutation	p.R1816H	1
PRKDC	SARC	chr8	48711822	48711822	G	T	Missense_Mutation		1
PRKDC	THYM	chr8	48805844	48805844	G	A	Silent	p.G1234	1
PRKDC	BLCA	chr8	48771464	48771464	C	T	Silent	p.L2097L	1
PRKDC	LGG	chr8	48744441	48744441	C	A	Missense_Mutation	p.M2732I	1
PRKDC	LUSC	chr8	48809844	48809844	G	A	Missense_Mutation	p.P1159S	1
PRKDC	STAD	chr8	48817430	48817430	A	G	Missense_Mutation	p.L1014S	1
PRKDC	BLCA	chr8	48744473	48744473	T	G	Missense_Mutation	p.T2722P	1
PRKDC	ESCA	chr8	48751732	48751733	-	A	Frame_Shift_Ins	p.Y2509fs	1
PRKDC	HNSC	chr8	48848436	48848436	G	C	Missense_Mutation		1
PRKDC	SARC	chr8	48801691	48801691	G	T	Missense_Mutation	p.D1387E	1
PRKDC	LIHC	chr8	48856584	48856584	G	-	Frame_Shift_Del	p.Q243fs	1
PRKDC	SKCM	chr8	48855799	48855799	T	A	Silent	p.A312A	1
PRKDC	BLCA	chr8	48771142	48771142	C	T	Missense_Mutation		1
PRKDC	BLCA	chr8	48771136	48771136	G	A	Missense_Mutation	p.P2135S	1
PRKDC	HNSC	chr8	48689409	48689409	T	A	Missense_Mutation	p.T4059S	1
PRKDC	LUAD	chr8	48752729	48752729	T	C	Silent	p.V2433V	1
PRKDC	STAD	chr8	48746805	48746805	T	C	Missense_Mutation		1
PRKDC	LUAD	chr8	48752729	48752729	T	C	Silent	p.V2434V	1
PRKDC	STAD	chr8	48815210	48815210	A	C	Missense_Mutation	p.L1063R	1
PRKDC	HNSC	chr8	48776002	48776002	G	A	Missense_Mutation	p.S1903L	1
PRKDC	SKCM	chr8	48802825	48802825	C	T	Missense_Mutation	p.G1354E	1
PRKDC	LUAD	chr8	48848447	48848447	T	A	Missense_Mutation	p.Y431F	1
PRKDC	CESC	chr8	48766714	48766714	G	C	Missense_Mutation	p.Q2274E	1
PRKDC	ESCA	chr8	48805866	48805866	C	-	Frame_Shift_Del	p.G1227fs	1
PRKDC	MESO	chr8	48794069	48794069	C	A	Missense_Mutation		1
PRKDC	STAD	chr8	48766746	48766746	T	A	Missense_Mutation	p.D2264V	1
PRKDC	THCA	chr8	48798638	48798638	C	A	Missense_Mutation	p.G1547V	1
PRKDC	BLCA	chr8	48695135	48695135	T	-	Frame_Shift_Del	p.R3733fs	1
PRKDC	GBM	chr8	48740782	48740782	G	A	Missense_Mutation		1
PRKDC	LIHC	chr8	48811075	48811075	T	-	Frame_Shift_Del	p.K1141fs	1
PRKDC	SKCM	chr8	48805808	48805808	G	A	Missense_Mutation	p.P1246S	1
PRKDC	LUAD	chr8	48839832	48839832	C	A	Missense_Mutation	p.D781Y	1
PRKDC	SKCM	chr8	48776081	48776081	G	A	Silent	p.L1876L	1
PRKDC	BLCA	chr8	48690396	48690396	G	A	Missense_Mutation		1
PRKDC	BLCA	chr8	48740849	48740849	C	T	Silent	p.E2818E	1
PRKDC	LIHC	chr8	48794656	48794656	C	T	Silent	p.V1592V	1
PRKDC	HNSC	chr8	48776002	48776002	G	A	Missense_Mutation		1
PRKDC	SARC	chr8	48749004	48749004	G	T	Missense_Mutation		1
PRKDC	LIHC	chr8	48689518	48689518	T	-	Frame_Shift_Del	p.K4022fs	1
PRKDC	UCEC	chr8	48840334	48840334	C	T	Silent	p.L752L	1
PRKDC	SKCM	chr8	48697727	48697727	G	A	Missense_Mutation	p.P3684L	1
PRKDC	BLCA	chr8	48802890	48802890	G	T	Missense_Mutation		1
PRKDC	LUAD	chr8	48713447	48713447	G	A	Silent	p.L3340L	1
PRKDC	KICH	chr8	48748950	48748951	-	C	Frame_Shift_Ins	p.G2632fs	1
PRKDC	SKCM	chr8	48839794	48839794	G	T	Silent	p.L793L	1
PRKDC	LUAD	chr8	48772236	48772236	C	T	Missense_Mutation	p.G2048E	1
PRKDC	UVM	chr8	48855865	48855865	G	A	Silent		1
PRKDC	STAD	chr8	48746928	48746928	C	T	Missense_Mutation	p.G2661R	1
PRKDC	CESC	chr8	48792189	48792189	T	C	Missense_Mutation	p.T1699A	1
PRKDC	LGG	chr8	48852241	48852241	G	A	Missense_Mutation		1
PRKDC	ESCA	chr8	48773474	48773474	G	T	Missense_Mutation		1
PRKDC	LIHC	chr8	48815178	48815178	T	A	Nonsense_Mutation	p.K1074*	1
PRKDC	STAD	chr8	48777212	48777212	T	C	Missense_Mutation	p.T1826A	1
PRKDC	SARC	chr8	48732007	48732007	G	T	Missense_Mutation		1
PRKDC	BLCA	chr8	48740729	48740729	C	T	Silent	p.Q2859Q	1
PRKDC	CESC	chr8	48686800	48686800	C	G	Silent		1
PRKDC	LGG	chr8	48697720	48697720	C	G	Missense_Mutation	p.M3686I	1
PRKDC	LUSC	chr8	48761740	48761740	C	A	Missense_Mutation	p.D2418Y	1
PRKDC	ESCA	chr8	48841652	48841653	CT	-	Frame_Shift_Del		1
PRKDC	STAD	chr8	48740750	48740750	T	C	Silent	p.P2852P	1
PRKDC	PAAD	chr8	48744458	48744458	G	A	Silent	p.L2727L	1
PRKDC	TGCT	chr8	48710955	48710955	A	G	Missense_Mutation		1
PRKDC	ESCA	chr8	48805866	48805866	C	-	Frame_Shift_Del	p.G1228fs	1
PRKDC	HNSC	chr8	48852134	48852134	G	A	Missense_Mutation		1
PRKDC	LIHC	chr8	48866941	48866941	T	-	Frame_Shift_Del	p.K155fs	1
PRKDC	SKCM	chr8	48855798	48855798	G	A	Missense_Mutation	p.L313F	1
PRKDC	BLCA	chr8	48839828	48839828	C	T	Missense_Mutation	p.R782K	1
PRKDC	HNSC	chr8	48706909	48706909	C	T	Missense_Mutation	p.E3537K	1
PRKDC	LUAD	chr8	48769775	48769775	T	C	Missense_Mutation	p.Y2183C	1
PRKDC	STAD	chr8	48776134	48776134	T	C	Missense_Mutation		1
PRKDC	LUAD	chr8	48772259	48772259	C	G	Missense_Mutation	p.M2040I	1
PRKDC	STAD	chr8	48772214	48772214	G	A	Silent	p.S2055S	1
PRKDC	LUAD	chr8	48805717	48805717	C	G	Missense_Mutation	p.G1276A	1
PRKDC	HNSC	chr8	48801649	48801649	C	A	Silent	p.L1402L	1
PRKDC	SKCM	chr8	48697704	48697704	C	T	Missense_Mutation	p.E3692K	1
PRKDC	LUAD	chr8	48794511	48794511	T	C	Missense_Mutation	p.K1641E	1
PRKDC	STAD	chr8	48740816	48740817	-	T	Frame_Shift_Ins	p.K2829fs	1
PRKDC	CESC	chr8	48794620	48794620	G	A	Silent	p.F1604	1
PRKDC	ESCA	chr8	48827892	48827892	C	G	Silent	p.L871	1
PRKDC	OV	chr8	48934837	48934837	G	A	Missense_Mutation		1
PRKDC	STAD	chr8	48801690	48801690	C	T	Missense_Mutation	p.V1389I	1
PRKDC	THCA	chr8	48774649	48774649	G	-	Frame_Shift_Del	p.R1986fs	1
PRKDC	BLCA	chr8	48719847	48719847	G	C	Missense_Mutation	p.L3200V	1
PRKDC	CESC	chr8	48792096	48792096	G	A	Missense_Mutation		1
PRKDC	GBM	chr8	48761735	48761735	G	A	Silent		1
PRKDC	LIHC	chr8	48826525	48826525	A	-	Frame_Shift_Del	p.F906fs	1
PRKDC	HNSC	chr8	48746868	48746868	C	T	Missense_Mutation		1
PRKDC	UCEC	chr8	48815130	48815130	T	C	Missense_Mutation	p.R1090_splice	1
PRKDC	SKCM	chr8	48690306	48690306	G	A	Missense_Mutation	p.P3994S	1
PRKDC	LUAD	chr8	48817536	48817536	C	A	Splice_Site	p.V979_splice	1
PRKDC	SKCM	chr8	48771423	48771423	G	A	Missense_Mutation	p.P2110L	1
PRKDC	BLCA	chr8	48711931	48711931	C	T	Silent		1
PRKDC	BLCA	chr8	48805803	48805803	G	A	Silent	p.F1247F	1
PRKDC	LIHC	chr8	48794060	48794060	T	C	Missense_Mutation	p.N1661D	1
PRKDC	HNSC	chr8	48805818	48805818	T	A	Missense_Mutation		1
PRKDC	SARC	chr8	48792217	48792217	G	T	Silent		1
PRKDC	LIHC	chr8	48701544	48701544	T	-	Frame_Shift_Del	p.M3608fs	1
PRKDC	UCEC	chr8	48856427	48856427	T	C	Missense_Mutation	p.Y265C	1
PRKDC	SKCM	chr8	48790352	48790352	G	A	Missense_Mutation	p.L1765F	1
PRKDC	BLCA	chr8	48826512	48826512	G	A	Silent		1
PRKDC	BLCA	chr8	48772246	48772246	A	T	Missense_Mutation	p.F2044I	1
PRKDC	HNSC	chr8	48746771	48746771	T	C	Missense_Mutation	p.D2712G	1
PRKDC	SKCM	chr8	48840367	48840367	A	G	Silent	p.I741I	1
PRKDC	LUAD	chr8	48805717	48805717	C	G	Missense_Mutation	p.G1277A	1
PRKDC	STAD	chr8	48701571	48701571	G	T	Missense_Mutation	p.P3600T	1
PRKDC	CESC	chr8	48839863	48839863	C	T	Silent	p.L770	1
PRKDC	ESCA	chr8	48805866	48805866	C	-	Frame_Shift_Del		1
PRKDC	PAAD	chr8	48790345	48790345	C	T	Missense_Mutation		1
PRKDC	LIHC	chr8	48695065	48695065	T	A	Missense_Mutation	p.D3756V	1
PRKDC	STAD	chr8	48733302	48733302	T	-	Frame_Shift_Del	p.N3105fs	1
PRKDC	SARC	chr8	48774647	48774647	G	T	Silent		1
PRKDC	BLCA	chr8	48761858	48761858	C	A	Missense_Mutation	p.M2379I	1
PRKDC	CESC	chr8	48736444	48736444	G	C	Missense_Mutation		1
PRKDC	LGG	chr8	48852241	48852241	G	A	Missense_Mutation	p.A328V	1
PRKDC	ESCA	chr8	48734354	48734354	C	A	Splice_Site	e66-1	1
PRKDC	LUSC	chr8	48746885	48746885	G	A	Missense_Mutation	p.S2674F	1
PRKDC	LIHC	chr8	48826474	48826474	T	C	Missense_Mutation		1
PRKDC	STAD	chr8	48761849	48761849	C	T	Silent	p.V2382V	1
PRKDC	PAAD	chr8	48744458	48744458	G	A	Silent		1
PRKDC	BLCA	chr8	48739311	48739311	G	C	Missense_Mutation	p.L2896V	1
PRKDC	ESCA	chr8	48790371	48790373	CAA	-	In_Frame_Del	p.L1758del	1
PRKDC	HNSC	chr8	48794645	48794645	A	G	Missense_Mutation		1
PRKDC	LIHC	chr8	48866992	48866992	A	-	Frame_Shift_Del	p.F138fs	1
PRKDC	SKCM	chr8	48691030	48691030	G	A	Missense_Mutation	p.S3947F	1
PRKDC	BLCA	chr8	48771142	48771142	C	T	Missense_Mutation	p.G2133R	1
PRKDC	HNSC	chr8	48697813	48697813	G	A	Silent	p.L3655L	1
PRKDC	LUAD	chr8	48845659	48845659	T	C	Missense_Mutation	p.D566G	1
PRKDC	LUAD	chr8	48719862	48719862	C	T	Missense_Mutation	p.E3195K	1
PRKDC	HNSC	chr8	48736553	48736553	A	G	Missense_Mutation	p.Y2929H	1
PRKDC	LUAD	chr8	48746951	48746951	C	G	Missense_Mutation	p.R2652T	1
PRKDC	HNSC	chr8	48697804	48697804	G	A	Silent	p.F3659F	1
PRKDC	SKCM	chr8	48794039	48794039	G	A	Missense_Mutation	p.P1668S	1
PRKDC	LUAD	chr8	48743246	48743246	T	C	Missense_Mutation	p.R2772G	1
PRKDC	STAD	chr8	48733488	48733488	T	C	Missense_Mutation	p.Y3043C	1
PRKDC	CESC	chr8	48855777	48855777	G	C	Missense_Mutation	p.L320V	1
PRKDC	ESCA	chr8	48841652	48841653	CT	-	Frame_Shift_Del	p.E713fs	1
PRKDC	OV	chr8	48956613	48956613	T	G	Missense_Mutation		1
PRKDC	STAD	chr8	48849059	48849059	C	T	Missense_Mutation	p.A378T	1
PRKDC	PRAD	chr8	48802925	48802925	T	C	Missense_Mutation	p.T1321A	1
PRKDC	THYM	chr8	48855833	48855833	C	T	Missense_Mutation		1
PRKDC	BLCA	chr8	48690357	48690357	C	T	Missense_Mutation	p.G3978S	1
PRKDC	GBM	chr8	48809762	48809762	T	C	Missense_Mutation		1
PRKDC	LIHC	chr8	48840413	48840413	A	-	Frame_Shift_Del	p.L726fs	1
PRKDC	HNSC	chr8	48713402	48713402	A	T	Silent		1
PRKDC	SKCM	chr8	48746891	48746891	G	A	Missense_Mutation	p.P2672L	1
PRKDC	LUAD	chr8	48689457	48689457	T	G	Missense_Mutation	p.I4043L	1
PRKDC	SKCM	chr8	48772229	48772229	C	T	Silent	p.Q2049Q	1
PRKDC	BLCA	chr8	48801695	48801695	C	A	Missense_Mutation		1
PRKDC	BLCA	chr8	48690396	48690396	G	A	Missense_Mutation	p.R3964C	1
PRKDC	HNSC	chr8	48848314	48848314	G	T	Silent		1
PRKDC	SARC	chr8	48866457	48866457	G	A	Silent	p.L177L	1
PRKDC	LIHC	chr8	48713502	48713502	A	-	Frame_Shift_Del	p.F3322fs	1
PRKDC	UCEC	chr8	48792086	48792086	G	A	Missense_Mutation	p.P1733L	1
PRKDC	SKCM	chr8	48740884	48740884	G	A	Missense_Mutation	p.L2807F	1
PRKDC	BLCA	chr8	48748973	48748973	G	A	Missense_Mutation		1
PRKDC	BLCA	chr8	48731993	48731993	G	A	Nonsense_Mutation	p.Q3138*	1
PRKDC	HNSC	chr8	48801649	48801649	C	A	Silent	p.L1401L	1
PRKDC	LUAD	chr8	48775078	48775078	C	A	Missense_Mutation	p.E1924D	1
PRKDC	SKCM	chr8	48707049	48707049	G	A	Missense_Mutation	p.P3490L	1
PRKDC	LUAD	chr8	48790322	48790322	C	T	Missense_Mutation	p.E1776K	1
PRKDC	STAD	chr8	48772214	48772214	G	T	Missense_Mutation	p.S2055R	1
PRKDC	LIHC	chr8	48690318	48690318	A	G	Missense_Mutation		1
PRKDC	STAD	chr8	48776075	48776075	C	T	Missense_Mutation	p.V1879M	1
PRKDC	LIHC	chr8	48839897	48839897	C	T	Missense_Mutation	p.G759D	1
PRKDC	STAD	chr8	48743276	48743276	T	-	Frame_Shift_Del	p.M2763fs	1
PRKDC	BLCA	chr8	48694764	48694764	A	G	Silent	p.L3816L	1
PRKDC	LGG	chr8	48749833	48749833	G	A	Silent	p.S2566S	1
PRKDC	LUSC	chr8	48794537	48794537	C	A	Missense_Mutation	p.W1632L	1
PRKDC	STAD	chr8	48815306	48815306	C	T	Missense_Mutation	p.R1031Q	1
PRKDC	PAAD	chr8	48691355	48691355	G	A	Missense_Mutation		1
PRKDC	ESCA	chr8	48841652	48841653	CT	-	Splice_Site	p.E713_splice	1
PRKDC	SARC	chr8	48866457	48866457	G	A	Silent		1
PRKDC	LIHC	chr8	48792161	48792176	TCCTCCAGACTGCCTC	-	Frame_Shift_Del	p.GGSLEE1703fs	1
PRKDC	BLCA	chr8	48719847	48719847	G	C	Missense_Mutation		1
PRKDC	LUAD	chr8	48743289	48743289	C	G	Missense_Mutation	p.K2757N	1
PRKDC	LUAD	chr8	48744402	48744402	T	-	Frame_Shift_Del	p.K2746fs	1
PRKDC	HNSC	chr8	48842449	48842449	A	G	Silent	p.I672I	1
PRKDC	HNSC	chr8	48697683	48697683	C	A	Nonsense_Mutation	p.E3700*	1
PRKDC	SKCM	chr8	48842431	48842431	C	T	Silent	p.K678K	1
PRKDC	LUAD	chr8	48711922	48711922	G	C	Missense_Mutation	p.F3381L	1
PRKDC	STAD	chr8	48772316	48772316	A	G	Silent	p.G2020G	1
PRKDC	CESC	chr8	48686800	48686800	C	G	Silent	p.L4106	1
PRKDC	LGG	chr8	48691168	48691168	G	A	Missense_Mutation		1
PRKDC	ESCA	chr8	48866909	48866910	-	T	Frame_Shift_Ins	p.I166fs	1
PRKDC	OV	chr8	48805847	48805847	C	T	Silent	p.S1233S	1
PRKDC	STAD	chr8	48740855	48740855	C	T	Silent	p.L2817L	1
PRKDC	THYM	chr8	48749793	48749793	G	T	Missense_Mutation		1
PRKDC	BLCA	chr8	48772207	48772207	C	T	Missense_Mutation	p.D2058N	1
PRKDC	GBM	chr8	48809791	48809791	A	G	Nonsense_Mutation		1
PRKDC	LIHC	chr8	48842539	48842539	A	-	Frame_Shift_Del	p.F642fs	1
PRKDC	HNSC	chr8	48761721	48761721	C	G	Missense_Mutation		1
PRKDC	SKCM	chr8	48809737	48809737	G	A	Silent	p.F1194F	1
PRKDC	LUAD	chr8	48866265	48866265	T	C	Silent	p.V212V	1
PRKDC	BLCA	chr8	48740729	48740729	C	T	Silent		1
PRKDC	BLCA	chr8	48711931	48711931	C	T	Silent	p.Q3378Q	1
PRKDC	ESCA	chr8	48734354	48734354	C	A	Splice_Site	.	1
PRKDC	HNSC	chr8	48801649	48801649	C	A	Silent		1
PRKDC	SARC	chr8	48845610	48845610	T	G	Silent	p.T582T	1
PRKDC	LIHC	chr8	48716034	48716034	A	-	Frame_Shift_Del	p.F3251fs	1
PRKDC	UCEC	chr8	48719865	48719865	C	G	Missense_Mutation	p.E3193Q	1
PRKDC	SKCM	chr8	48749885	48749885	A	G	Missense_Mutation	p.I2549T	1
PRKDC	BLCA	chr8	48731990	48731990	C	T	Missense_Mutation		1
PRKDC	BLCA	chr8	48866272	48866272	G	A	Missense_Mutation	p.S210L	1
PRKDC	LUAD	chr8	48840357	48840357	C	A	Missense_Mutation	p.V745F	1
PRKDC	SKCM	chr8	48701521	48701521	G	A	Silent	p.A3615A	1
PRKDC	LUAD	chr8	48801713	48801713	C	A	Missense_Mutation	p.S1381I	1
PRKDC	STAD	chr8	48749922	48749922	G	A	Missense_Mutation	p.R2538W	1
PRKDC	CHOL	chr8	48710796	48710796	A	G	Splice_Site	.	1
PRKDC	STAD	chr8	48852143	48852143	T	C	Missense_Mutation	p.I361V	1
PRKDC	PAAD	chr8	48852162	48852162	C	A	Silent		1
PRKDC	STAD	chr8	48845618	48845618	C	-	Frame_Shift_Del	p.D580fs	1
PRKDC	BLCA	chr8	48803019	48803019	A	C	Silent	p.L1290L	1

Copy number variation (CNV) of PRKDC
* Click on the image to open the original image in a new window.

Fusion gene breakpoints (product of the structural variants (SVs)) across PRKDC
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion genes with this translation factor from FusionGDB2.0.

FusionGDB2 ID	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
97904	N/A	BF800878	ACACA	chr17	35765578	+	PRKDC	chr8	48798797	+
97904	N/A	BG151582	DNASE1	chr16	3672204	-	PRKDC	chr8	48784727	+
97904	N/A	BE931170	ERC1	chr12	1372250	-	PRKDC	chr8	48722211	-
97904	N/A	BE837717	FGF13	chrX	138205572	+	PRKDC	chr8	48685850	-
97904	N/A	BE837566	FKBP9	chr7	33037806	-	PRKDC	chr8	48685883	-
97904	HNSC	TCGA-CN-5370-01A	FOXN1	chr17	26833461	+	PRKDC	chr8	48697878	-
97904	STAD	TCGA-FP-8209-01A	FOXN2	chr2	48541953	+	PRKDC	chr8	48744487	-
97904	BRCA	TCGA-EW-A1P4-01A	KCMF1	chr2	85255179	+	PRKDC	chr8	48771547	-
97904	BRCA	TCGA-EW-A1P4-01A	KCMF1	chr2	85255179	+	PRKDC	chr8	48772320	-
97904	CESC	TCGA-VS-A8EI-01A	KCNC3	chr19	50823850	-	PRKDC	chr8	48730122	-
97904	N/A	AK022387	MAP4K5	chr14	50945505	-	PRKDC	chr8	48711771	-
97904	N/A	AI634126	MRPS34	chr16	1822023	-	PRKDC	chr8	48685673	+
100456	N/A	BQ320900	PRKDC	chr8	48744744	-	ACADVL	chr17	7127688	+
97600	STAD	TCGA-BR-A4J7-01A	PRKDC	chr8	48751709	-	ANKRD16	chr10	5904654	-
85093	BRCA	TCGA-E9-A1RE-01A	PRKDC	chr8	48694723	-	ARHGAP23	chr17	36635677	+
68849	BRCA	TCGA-E9-A1RE-01A	PRKDC	chr8	48694723	-	ARHGAP23P1	chr16	33729010	-
68849	BRCA	TCGA-E9-A1RE-01A	PRKDC	chr8	48694939	-	ARHGAP23P1	chr16	33729010	-
68849	PCPG	TCGA-QT-A5XO-01A	PRKDC	chr8	48769717	-	CA3	chr8	86351941	+
92523	BRCA	TCGA-AN-A0FD-01A	PRKDC	chr8	48744375	-	CEP290	chr12	88533341	-
93728	COAD	TCGA-RU-A8FL-01A	PRKDC	chr8	48824970	-	CLVS1	chr8	62204877	+
93728	COAD	TCGA-RU-A8FL-01A	PRKDC	chr8	48824970	-	CLVS1	chr8	62212236	+
101903	N/A	BE548041	PRKDC	chr8	48685672	-	DCC	chr18	50790846	+
68849	BRCA	TCGA-C8-A12L	PRKDC	chr8	48761714	-	DEFB103A	chr8	7739944	+
68849	BRCA	TCGA-C8-A12L-01A	PRKDC	chr8	48761715	-	DEFB103B	chr8	7286651	-
76655	BRCA	TCGA-AC-A2QH	PRKDC	chr8	48866366	-	DOCK4	chr7	111585853	-
94090	BRCA	TCGA-A8-A09A-01A	PRKDC	chr8	48848292	-	GSR	chr8	30567419	-
88882	N/A	BF088350	PRKDC	chr8	48710913	+	LAMB1	chr7	107568347	-
87029	LUAD	TCGA-86-7713-01A	PRKDC	chr8	48730011	-	MYO5A	chr15	52667657	-
102301	PRAD	TCGA-G9-6342-01A	PRKDC	chr8	48733342	-	NEDD4L	chr18	56024483	-
102301	PRAD	TCGA-G9-6342-01A	PRKDC	chr8	48740628	-	NEDD4L	chr18	56024483	-
102153	LUSC	TCGA-33-4582	PRKDC	chr8	48824969	-	PRIM2	chr6	57244698	+
102153	LUSC	TCGA-33-4582-01A	PRKDC	chr8	48824970	-	PRIM2	chr6	57244699	+
97904	N/A	AI961454	PRKDC	chr8	48686030	+	PRKDC	chr8	48686077	-
97904	N/A	W28344	PRKDC	chr8	48777304	+	PRKDC	chr8	48772204	-
102741	N/A	BI493637	PRKDC	chr8	48731937	-	RTN4	chr2	55253746	+
94123	N/A	BU587911	PRKDC	chr8	48714800	-	SLC38A2	chr12	46752066	-
102204	BRCA	TCGA-D8-A1XS-01A	PRKDC	chr8	48706851	-	SPIDR	chr8	48508373	+
102204	CESC	TCGA-EA-A1QT-01A	PRKDC	chr8	48730011	-	SPIDR	chr8	48508373	+
102204	HNSC	TCGA-BA-4078-01A	PRKDC	chr8	48839754	-	SPIDR	chr8	48508373	+
102204	STAD	TCGA-BR-7901-01A	PRKDC	chr8	48746757	-	SPIDR	chr8	48191858	+
101436	N/A	BF821929	PRKDC	chr8	48859603	+	SVIL	chr10	29840056	-
68849	STAD	TCGA-BR-8295-01A	PRKDC	chr8	48868434	-	TOMM70A	chr3	100092489	-
96345	PRAD	TCGA-KK-A8IB-01A	PRKDC	chr8	48866180	-	UBE2V2	chr8	48955593	+
102974	N/A	W58317	PRKDC	chr8	48740728	-	WDR83OS	chr19	12779364	-
97904	N/A	CV412890	RREB1	chr6	7150362	+	PRKDC	chr8	48699887	-
97904	N/A	BI493638	RTN4	chr2	55253746	-	PRKDC	chr8	48731937	+
97904	BRCA	TCGA-D8-A1X5-01A	SLC39A14	chr8	22224921	+	PRKDC	chr8	48762064	-
97904	STAD	TCGA-B7-5816-01A	SPIDR	chr8	48353104	+	PRKDC	chr8	48686938	-
97904	N/A	BF923303	TIMP3	chr22	33200159	+	PRKDC	chr8	48827911	-
97905	N/A	BG961504	VASH1	chr14	77246725	-	PRKDC	chr8	48844131	+

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Prognostic Analysis

Kaplan-Meier plots with logrank tests of overall survival (OS)

Cancer type

Translation factor

Coefficent

Hazard ratio

Wald test pval

Likelihool ratio pval

Logrank test pval

# samples

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Translation factor and Gender

Differential gene expression between female and male. (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
SARC	PRKDC	0.0014397947591415	0.039
LAML	PRKDC	0.00189963717674349	0.049
TGCT	PRKDC	0.00201355115997846	0.05
LUAD	PRKDC	0.00504613415287032	0.12
LIHC	PRKDC	0.023749034046097	0.55
READ	PRKDC	0.0303544001073417	0.67
THCA	PRKDC	0.0428258681903823	0.9
KIRP	PRKDC	1.82653818167677e-05	0.00051

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Translation factor and Age

Differential gene expression between young and old age groups (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
LIHC	PRKDC	0.0145227624618117	0.45
SKCM	PRKDC	0.0334117240078911	1
ESCA	PRKDC	0.00029345495681647	0.0097
COAD	PRKDC	0.007859123100336	0.25

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Related Drugs

Drugs targeting genes involved in this translation factor.
(DrugBank Version 5.1.8 2021-05-08)

UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
P78527	DB00201	Caffeine	Inhibitor	Small molecule	Approved
P78527	DB00201	Caffeine	Inhibitor

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Related Diseases

Diseases associated with this translation factor.
(DisGeNet 4.0)

Disease ID	Disease Name	# PubMeds	Disease source
C4014833	IMMUNODEFICIENCY 26 WITH OR WITHOUT NEUROLOGIC ABNORMALITIES	3	CTD_human;ORPHANET;UNIPROT
C0376358	Malignant neoplasm of prostate	2	CTD_human
C0007137	Squamous cell carcinoma	1	CTD_human
C0010606	Adenoid Cystic Carcinoma	1	CTD_human
C0019147	Hepatic Coma	1	CTD_human
C0019151	Hepatic Encephalopathy	1	CTD_human
C0019193	Hepatitis, Toxic	1	CTD_human
C0085110	Severe Combined Immunodeficiency	1	GENOMICS_ENGLAND
C0494261	Combined immunodeficiency	1	GENOMICS_ENGLAND
C0751197	Fulminant Hepatic Failure with Cerebral Edema	1	CTD_human
C0751198	Hepatic Stupor	1	CTD_human
C1262760	Hepatitis, Drug-Induced	1	CTD_human
C3658290	Drug-Induced Acute Liver Injury	1	CTD_human
C4277682	Chemical and Drug Induced Liver Injury	1	CTD_human
C4279912	Chemically-Induced Liver Toxicity	1	CTD_human