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Center for Computational Systems Medicine
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Gene Summary

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Translation studies in PubMed

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Exon Skipping Events

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Expression

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Expression Regulation

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Associated Genes

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Protein 3D Structure

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Protein-Protein Interaction

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Mutations

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Prognostic Analysis

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Gender Association

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Age Association

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Related Drugs

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Related Diseases

Translation Factor: EIF3H (NCBI Gene ID:8667)


Gene Summary

check button Gene Summary
Gene InformationGene Name: EIF3H
Gene ID: 8667
Gene Symbol

EIF3H

Gene ID

8667

Gene Nameeukaryotic translation initiation factor 3 subunit H
SynonymsEIF3S3|eIF3-gamma|eIF3-p40
Cytomap

8q23.3-q24.11

Type of Geneprotein-coding
Descriptioneukaryotic translation initiation factor 3 subunit HeIF-3-gammaeIF3 p40 subuniteukaryotic translation initiation factor 3 subunit 3eukaryotic translation initiation factor 3, subunit 2 (beta, 36kD)eukaryotic translation initiation factor 3, subunit 3
Modification date20200313
UniProtAcc

O15372


check button Child GO biological process term(s) under GO:0006412
GO IDGO term
GO:0006417Regulation of translation
GO:0008135Translation factor activity, RNA binding
GO:0005840Ribosome
GO:0006413Translational initiation
GO:0006412Translation


check button Gene ontology of translaction factor with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneEIF3H

GO:0006413

translational initiation

17581632



check button Inferred gene age of translation factor.
GeneInferred gene age group among (0 - 67.6], (67.6 - 355.7], (355.7 - 733], (733 - 1119.25], >1119.25
EIF3H>1119.25


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Translation Studies in PubMed

check button We searched PubMed using 'EIF3H[title] AND translation [title] AND human.'
GeneTitlePMID
EIF3HEukaryotic translation initiation factor EIF3H potentiates gastric carcinoma cell proliferation30060823


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Exon Skipping Events

check buttonSkipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
For more annotations, please visit our ExonSkipDB.
all structure

check button Open reading frame (ORF) analsis of exon skipping events based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ENSTExon skip start (DNA)Exon Skip end (DNA)ORF
ENST00000521861117661044117661165Frame-shift
ENST00000521861117668094117668244In-frame
ENST00000521861117669453117669553Frame-shift
ENST00000521861117671051117671219In-frame

check button Exon skipping position in the amino acid sequence.
ENSTExon skip start (DNA)Exon Skip end (DNA)Len(transcript seq)Exon skip start (mRNA)Exon Skip end (mRNA)Len(amino acid seq)Exon skip start (AA)Exon Skip end (AA)
ENST000005218611176680941176682443976582731352186235
ENST00000521861117671051117671219397631448135296152

check button Potentially (partially) lost protein functional features of UniProt.
UniProtAccExon skip start (AA)Exon Skip end (AA)Function feature start (AA)Function feature end (AA)Functional feature typeFunctional feature desc.
O153721862351352ChainID=PRO_0000213961;Note=Eukaryotic translation initiation factor 3 subunit H
O15372961521352ChainID=PRO_0000213961;Note=Eukaryotic translation initiation factor 3 subunit H
O153729615239173DomainNote=MPN;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01182
O153729615297109HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3J8B
O1537296152115121Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3J8B
O1537296152132143HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3J8B
O1537296152148152Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3J8B
O15372186235197200Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3J8B
O15372186235203206Beta strandOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3J8B
O15372186235209215HelixOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3J8B
O15372186235216219TurnOntology_term=ECO:0000244;evidence=ECO:0000244|PDB:3J8B


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Expression


check buttonGene expression level across TCGA pancancer
all structure

check buttonGene expression level across GTEx pantissue
all structure

check buttonExpression level of gene isoforms across TCGA pancancer
all structure

check buttonExpression level of gene isoforms across GTEx pantissue
all structure

check buttonCancer(tissue) type-specific expression level of Translation factor using z-score distriution
all structure

check buttonDifferential expression between tumor and matched normal (in the cancer types with more than 10 matched samples)
all structure
Cancer typeTranslation factorFCadj.pval
LIHCEIF3H-1.904408803919850.000201991820198738
THCAEIF3H-1.363898051608820.00492925389458784
LUSCEIF3H-2.961376895547721.45608838900009e-05
KIRCEIF3H-1.03322192578129.65225899474882e-06


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Expression Regulation


check buttonTranslation factor expression regulation through miRNA binding
Cancer typeGenemiRNATargetScan binding score (Context++ score percentile)CoefficientPvalue


check buttonTranslation factor expression regulation through methylation in the promoter of Translation factor
all structure
Cancer typeGenemethyl group bmethyl group aDEG pvalavg methyl in bavg methyl in aavg exp in bavg exp in a

check buttonTranslation factor expression regulation through methylation in the gene body of Translation factor (positive regulation)
all structure
Cancer typeGenemethyl group bmethyl group aDEG pvalavg methyl in bavg methyl in aavg exp in bavg exp in a
KICHEIF3H320.02785261525157160.6562247660979640.552648913043478-0.399203664515302-0.577078031604
PAADEIF3H320.02293430189252390.6378682768565250.572874436090226-0.364757141192866-0.219304052011951

check buttonTranslation factor expression regulation through copy number variation of Translation factor
all structure
Cancer typeGeneCoefficientPvalue
KICHEIF3H0.0824434260.010673368
MESOEIF3H0.1203230670.013704182
UCECEIF3H0.1388288240.018375828

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Associated Genes


check button Strongly correlated genes belong to cellular important gene groups with EIF3H (coefficient>0.8, pval<0.05, node color based on FC between tumor and matched normal). Significantly associated important genes in the individual cancer types. * Cell metabolism gene: cell metabolism genes from REACTOME (black edge), IUPHAR: drug target genes from IUPHAR (blue edge), Kinase: human kinase genes (brown edge), CGC: cancer gene census genes (orange edge), TSG: tumor suppresor genes (purple edge), Epifactor: epigenetic factors (light blue edge), TF: transcription factors (green)
all structure
Cancer typeGene groupTranslation factorCorrelated geneCoefficientPvalue
LGGCGCEIF3HNACA0.8015561835.05E-120


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Protein structure


check button Protein 3D structure
Visit iCn3D.


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Protein-Protein Interaction


check button Protein-protein interaction networks
* Overlap between up-regulated DEGs (log2FC<-1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))
all structure

check buttonOverlap between down-regulated DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))
all structure
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* Edge colors based on TCGA cancer types.

check button* Overlap between DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network per cancer (center: Translation factor, node: DEGs, node color: log2FC, edges: weighted by -log2(adj.P))
all structure
Cancer typeTranslation factorInteracting protein coding geneFCadj.pval
COADEIF3HEIF3K-1.815560463906970.000109195709228516
KICHEIF3HEIF3I1.573100692208020.000139892101287842
LUADEIF3HEIF3D-2.47246314411060.000299564272708473
PRADEIF3HEIF3A1.136803283919520.000363360004697762
LIHCEIF3HEIF3C-1.230745218839720.00126327311470459
KIRPEIF3HEIF3F-2.666798348731280.00143672106787562
BRCAEIF3HEIF3I-1.722334592755310.00191218761269043
KIRCEIF3HEIF3F-1.29927472561020.00267981494905134
BLCAEIF3HEIF3F-2.420453545345880.00457763671875
KIRPEIF3HEIF3G-2.41783229621290.00471024587750435
BLCAEIF3HEIF3A-4.451040583077470.00532913208007812
LIHCEIF3HEIF3E-5.17223325998540.00593802028362182
KICHEIF3HEIF3D-5.649428670230170.0202749371528625
UCECEIF3HEIF3G-3.350783346965710.03125
BLCAEIF3HEIF3G-3.077075596490910.0323410034179688
LUADEIF3HEIF3B-5.804355875467621.0542655358657e-09
KIRCEIF3HEIF3D-2.335018768320581.16831478033445e-08
BRCAEIF3HEIF3G1.879483850112711.9107949115022e-06
KIRCEIF3HEIF3B-1.563132637845172.35252849767166e-12
LIHCEIF3HEIF3D-2.518543046327992.35319665208461e-06
STADEIF3HEIF3B-4.77246609720073.25962901115418e-08
LUADEIF3HEIF3M-1.54295739683084.40678669801292e-06
HNSCEIF3HEIF3B2.62025542636044.48234413852334e-06
KIRPEIF3HEIF3B-2.75922970429744.6566128730774e-09
BRCAEIF3HEIF3A-1.2182155731487.39403582934137e-06
KIRCEIF3HEIF3E-4.498241012194627.8509870430991e-09
KIRCEIF3HEIF3M-2.008881346589988.07326657761222e-05
BRCAEIF3HEIF3E-1.484083480624639.51829316317813e-08


check button Protein-protein interactors with this translation factor (BIOGRID-3.4.160)
PPI interactors with EIF3H
ABI3, CCDC85B, EIF4A2, EIF3A, EIF1B, EIF3G, DISC1, BAI1, CSNK2A1, CSNK2A2, CSNK2B, EIF4G1, EIF3E, ABCE1, EIF3B, EIF3C, EIF3D, EIF3F, USP3, WDR48, EIF3I, EIF3J, EIF4G3, ARPC5, EIF3M, EIF3K, EIF3L, PRRC2B, TMEM203, EIF3FP3, MGMT, SRRM2, SRRM1, TADA2A, UBC, Eif3a, Itsn2, CDK2, RPS6KB1, PAXIP1, SMURF1, HSP90AA1, HSP90AB1, DDX3X, gag-pol, PAN2, CD81, IGSF8, ICAM1, NPM1, TARDBP, HECW2, RPS20, RPS9, YTHDF2, NCK2, ABI2, SORBS3, RSPH9, EIF3CL, HNRNPA1, UNK, COPS5, NUMA1, SKIV2L2, NAP1L1, PDCD4, SFN, NTRK1, HERC2, XPO1, LIMA1, BAG6, Eif3e, Eif3i, Rpl35, Ksr1, SPTBN1, EIF4A1, PSMD12, GPBP1L1, CPNE2, CYLD, SOD1, G3BP1, BRCA1, LNX1, ASCC3, ATP5J2, BDP1, C9orf114, CDC27, CIT, COPS4, DCTN2, EIF4G2, EMG1, EXOSC2, FAM50A, FDPS, GTF2E1, LUC7L3, MED22, MINOS1, MRPS18B, NDUFA9, NUTF2, PMF1, PPCS, PTTG1, SKA3, SNRPD3, TAF1, TAF2, TRA2B, UBA3, XRN2, ZNF598, UBE2M, EFTUD2, FAM188B, PRKCZ, ESR2, HEXIM1, MEPCE, LARP7, EZH2, RECQL4, ZFP36L2, TP53, KIAA1429, EIF4B, ATG16L1, METTL3, MAVS, CD74, DDX60, BIRC3, NFX1, WWP2, ABI1, SORBS2, PLEKHA4, PEBP1, RAB5A, nsp1, ESR1, ANLN, ECT2, KIF14, MKI67, nsp2ab, CIC, Apc2, RBM39, CUL4A, YAP1, KRT9, PUF60, HNRNPU, KIF11, KRT18, HSPA9, SERBP1, PA2G4, EEF1A1, TUBA1B, NCL, XRCC6, YBX1, ACTB, PRMT5, SSB, ACTR3, CLTC, RPL4, TUFM, DHX29, DCP1A, HNRNPM, DNAJA1, KRT73, HNRNPL, HDLBP, LMNB1, SRP68, CTTN, LYAR, ILF3, LTV1, EDC3, MVP, LRRC47, SLC25A13, HADHB, AIFM1, SCYL2, EIF4E, EIF4EBP2, EIF4ENIF1, EIF4EBP1, ANGEL1, DDX58, PARK2, SNAI1, RPL6, ACBD5, ELOVL5, NAA38, PAEP, GIGYF1, EP300, CCNF, SLFN11, KLF15, KLF16, KLF8,


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Mutations


check button Clinically associated variants from ClinVar.
GeneChrPositionRefSeqVarSeqRefSeeqVarTypePathogenicDiseaseVarInfo


check button nsSNVs with sample frequency (size of circle) from TCGA 33 cancers.
all structure


check button SNVs and Indels
GeneCancer typeChromosomeStartEndRefSeeqMutSeqMutation typeAAchange# samples
EIF3HLUADchr8117658741117658741CASilentp.P310P5
EIF3HCOADchr8117658786117658786CTSilentp.P295P5
EIF3HBRCAchr8117671073117671073CANonsense_Mutationp.E146*4
EIF3HHNSCchr8117671059117671059GASilentp.L150L3
EIF3HCESCchr8117738394117738394GCMissense_Mutation3
EIF3HESCAchr8117658786117658786CTSilent3
EIF3HLIHCchr8117669472117669472T-Frame_Shift_Delp.K180fs2
EIF3HUCECchr8117671056117671056ACMissense_Mutationp.I151M2
EIF3HCESCchr8117767936117767936GAMissense_Mutation2
EIF3HPAADchr8117668207117668207CTMissense_Mutation2
EIF3HUCECchr8117738277117738277CAMissense_Mutationp.E89D2
EIF3HLIHCchr8117669464117669464A-Frame_Shift_Delp.S183fs2
EIF3HPAADchr8117668207117668207CTMissense_Mutationp.E199K2
EIF3HSTADchr8117658744117658744CTSilent2
EIF3HSTADchr8117658744117658744CTSilentp.Q309Q2
EIF3HLIHCchr8117658834117658834CTSilent2
EIF3HSTADchr8117658816117658816AGSilentp.N285N2
EIF3HCHOLchr8117767993117767993GTMissense_Mutation2
EIF3HSTADchr8117671196117671196GAMissense_Mutationp.R105W2
EIF3HCHOLchr8117767994117767994ATMissense_Mutation2
EIF3HLIHCchr8117668129117668129CAMissense_Mutation2
EIF3HSTADchr8117658772117658772TAMissense_Mutationp.D300V2
EIF3HCHOLchr8117767993117767993GTMissense_Mutationp.S15Y2
EIF3HLUADchr8117671091117671091ATMissense_Mutationp.Y140N2
EIF3HSARCchr8117671185117671185GTSilent2
EIF3HLIHCchr8117658834117658834CTSilentp.Q279Q2
EIF3HCHOLchr8117767994117767994ATMissense_Mutationp.S15T2
EIF3HSTADchr8117671101117671101AGSilentp.S136S2
EIF3HHNSCchr8117668121117668121TCSilentp.K227K2
EIF3HSTADchr8117658748117658748GAMissense_Mutationp.P308L2
EIF3HHNSCchr8117658759117658759GCSilentp.L304L2
EIF3HCESCchr8117668117117668117CTMissense_Mutation2
EIF3HLIHCchr8117668235117668235T-Frame_Shift_Delp.K189fs2
EIF3HESCAchr8117668098117668098CTMissense_Mutationp.S235N2
EIF3HUCECchr8117668111117668111GTMissense_Mutationp.L231I2
EIF3HSKCMchr8117658839117658839GANonsense_Mutationp.Q278*1
EIF3HLUSCchr8117658799117658799CAMissense_Mutationp.R305L1
EIF3HKIRCchr8117657285117657285TCMissense_Mutationp.K340R1
EIF3HSKCMchr8117657305117657305GASilentp.F333F1
EIF3HLIHCchr8117661153117661153C-Frame_Shift_Delp.G240fs1
EIF3HGBMchr8117738327117738327CTMissense_Mutationp.E87K1
EIF3HKIRPchr8117661151117661151TGMissense_Mutationp.K255T1
EIF3HSKCMchr8117658804117658824CTGGCGCTGCATATTCTCCTG-In_Frame_Delp.QENMQRQ283del1
EIF3HCESCchr8117668117117668117CTMissense_Mutationp.E229K1
EIF3HGBMchr8117738327117738327CTMissense_Mutation1
EIF3HKIRPchr8117661151117661151TGMissense_Mutation1
EIF3HCESCchr8117767936117767936GAMissense_Mutationp.S34L1
EIF3HLUADchr8117671153117671153CGMissense_Mutationp.W119S1
EIF3HHNSCchr8117658759117658759GCSilent1
EIF3HPAADchr8117668207117668207CTMissense_Mutationp.E213K1
EIF3HLUADchr8117768021117768021CANonsense_Mutationp.E6*1
EIF3HHNSCchr8117668241117668241CGMissense_Mutation1
EIF3HREADchr8117661063117661063TCSilentp.Q270Q1
EIF3HLIHCchr8117738284117738284TCMissense_Mutation1
EIF3HLUADchr8117768022117768022CTSilentp.K5K1
EIF3HHNSCchr8117668121117668121TCSilent1
EIF3HREADchr8117669471117669471CAMissense_Mutationp.K180N1
EIF3HBLCAchr8117661114117661114CGMissense_Mutation1
EIF3HHNSCchr8117671059117671059GASilent1
EIF3HBLCAchr8117671172117671172CAMissense_Mutation1
EIF3HSKCMchr8117658843117658843CASplice_Site.1
EIF3HBLCAchr8117661114117661114CGMissense_Mutationp.M253I1
EIF3HLIHCchr8117671203117671203TGMissense_Mutationp.E102D1
EIF3HLUADchr8117671063117671063ATMissense_Mutationp.V149D1
EIF3HSKCMchr8117768029117768029GAMissense_Mutationp.S3F1
EIF3HLIHCchr8117668129117668129CAMissense_Mutationp.A225S1
EIF3HESCAchr8117658786117658786CTSilentp.P2951
EIF3HLUSCchr8117669519117669519TCSilentp.L178L1
EIF3HSTADchr8117669464117669464A-Frame_Shift_Delp.S197fs1
EIF3HHNSCchr8117668241117668241CGMissense_Mutationp.L187F1
EIF3HSKCMchr8117658843117658843CASplice_Site1
EIF3HLUSCchr8117671117117671117CAMissense_Mutationp.R145L1

check buttonCopy number variation (CNV) of EIF3H
* Click on the image to open the original image in a new window.
all structure

check buttonFusion gene breakpoints (product of the structural variants (SVs)) across EIF3H
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure


check button Fusion genes with this translation factor from FusionGDB2.0.
FusionGDB2 IDDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
102023STADTCGA-CG-5721-01AAFF1chr487869723+EIF3Hchr8117669553-
102023ESCATCGA-R6-A6Y0AZIN1chr8103876034-EIF3Hchr8117671219-
102023N/AFN176720CHST9chr1824712847+EIF3Hchr8117768062-
102023N/AXX000007CYTH1chr1776778284-EIF3Hchr8117768037-
100840N/AAI302586EIF3Hchr8117658757+ACSL5chr10114181373-
94182STADTCGA-D7-5577-01AEIF3Hchr8117767905-ANKHchr514716944-
97651STADTCGA-CD-A486-01AEIF3Hchr8117738255-BLVRBchr1940964452-
96044N/ADA942074EIF3Hchr8117658793-CMC1chr328287324+
66114N/AFN113375EIF3Hchr8117661092-COPS3chr1717169565+
103164N/AAI861912EIF3Hchr8117657177+DCAF11chr1424584383-
98273BRCATCGA-AQ-A04L-01BEIF3Hchr8117668095-EFR3Achr8133025212+
102023N/AAA648095EIF3Hchr8117668129-EIF3Hchr8117661089+
102023N/AAW372241EIF3Hchr8117671093-EIF3Hchr8117669490+
102023N/AAW965128EIF3Hchr8117658734-EIF3Hchr8117671083-
102023N/ACV398950EIF3Hchr8117723446+EIF3Hchr8117723301-
87715N/AAA078963EIF3Hchr8117762061+HECTD1chr1431612752+
101214N/AAA730868EIF3Hchr8117762063+HSP90AA1chr14102547385+
101214N/AAA894486EIF3Hchr8117762059+HSP90AA1chr14102547385+
98609N/AAA506858EIF3Hchr8117657071-MFHAS1chr88643553-
99256N/ABG033373EIF3Hchr8117668102-OLA1chr2175063270+
99049BRCATCGA-BH-A1F0-01AEIF3Hchr8117738255-RAD21chr8117879000-
99049LIHCTCGA-CC-A8HV-01AEIF3Hchr8117738255-RAD21chr8117870697-
95319STADTCGA-HU-A4GCEIF3Hchr8117738254-UBBchr1716285215+
98040STADTCGA-VQ-A94OEIF3Hchr8117738254-URI1chr1930476129+
98040STADTCGA-VQ-A94O-01AEIF3Hchr8117738255-URI1chr1930476130+
100020STADTCGA-BR-A4J7EIF3Hchr8117738254-WDR27chr6169857729-
70213LUADTCGA-86-8280-01AEIF3Hchr8117767905-ZNF596chr8190824+
102023N/AFN088420EIF4EBP2chr1072188244-EIF3Hchr8117661079-
102023N/ABE090337FAM129Bchr9130279206-EIF3Hchr8117738411-
102023Non-Cancer61NFBN1chr1548888479-EIF3Hchr8117671219-
102023STADTCGA-D7-5578GTF3C2chr227579605-EIF3Hchr8117661165-
102023COADTCGA-AA-A03F-01AGUK1chr1228336522+EIF3Hchr8117658739-
102023N/AFN058991KMT2Cchr7151989230-EIF3Hchr8117657088+
102023OVTCGA-10-0936NCOA2chr871126137-EIF3Hchr8117671219-
102023SKCMTCGA-W3-AA1V-06BPPP2R2Achr826151256+EIF3Hchr8117671219-
102023BLCATCGA-BT-A20W-01ARAD21chr8117868405-EIF3Hchr8117671219-
102023BLCATCGA-BT-A20W-01ARAD21chr8117886850-EIF3Hchr8117661165-
102023BRCATCGA-E2-A14R-01ARAD21chr8117866484-EIF3Hchr8117671219-
102023LUSCTCGA-63-A5MYRAD21chr8117886849-EIF3Hchr8117738411-
102023OVTCGA-13-1507RAD21chr8117874079-EIF3Hchr8117738411-
102023OVTCGA-13-1507RAD21chr8117875368-EIF3Hchr8117671219-
102023OVTCGA-13-1507-01ARAD21chr8117874080-EIF3Hchr8117738411-
102023OVTCGA-13-1507-01ARAD21chr8117875369-EIF3Hchr8117671219-
102023OVTCGA-13-1507-01ARAD21chr8117878825-EIF3Hchr8117738411-
102023READTCGA-DY-A1DERAD21chr8117886602-EIF3Hchr8117671219-
102023READTCGA-DY-A1DERAD21chr8117886849-EIF3Hchr8117671219-
102023READTCGA-DY-A1DERAD21chr8117886850-EIF3Hchr8117671219-
102023STADTCGA-BR-7715RAD21chr8117878824-EIF3Hchr8117738411-
102023STADTCGA-VQ-AA6DRAD21chr8117868404-EIF3Hchr8117671219-
102023UCSTCGA-N8-A4PPRAD21chr8117864186-EIF3Hchr8117738411-
102023UCSTCGA-N8-A4PPRAD21chr8117864187-EIF3Hchr8117738411-
102023BRCATCGA-BH-A1FD-01ARP1chr855471880+EIF3Hchr8117671219-
102023BRCATCGA-E2-A106-01ASLC30A8chr8117963358+EIF3Hchr8117671219-
102023N/ADT215537TMEM154chr4153569698-EIF3Hchr8117768059-
102023Non-CancerTCGA-E9-A1RB-11ATRPS1chr8116680772-EIF3Hchr8117671219-
102023STADTCGA-VQ-A94OURI1chr1930433571+EIF3Hchr8117668244-
102023STADTCGA-VQ-A94O-01AURI1chr1930433571+EIF3Hchr8117661165-
102023STADTCGA-VQ-A94O-01AURI1chr1930433571+EIF3Hchr8117671219-
102025BRCATCGA-AC-A5XU-01AZNF415chr1953618957-EIF3Hchr8117671219-


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Prognostic Analysis


check button Kaplan-Meier plots with logrank tests of overall survival (OS)
all structure
Cancer typeTranslation factorCoefficentHazard ratioWald test pvalLikelihool ratio pvalLogrank test pval# samples


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Translation factor and Gender


check button Differential gene expression between female and male. (Wilcoxon test, pval<0.05)
all structure
Cancer typeTranslation factorpvaladj.p
LIHCEIF3H0.0001473389759162050.0041
TGCTEIF3H0.0001627836507598430.0044
KIRCEIF3H0.0008411217546084380.022
KIRPEIF3H0.04957811540131291

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Translation factor and Age


check button Differential gene expression between young and old age groups (Wilcoxon test, pval<0.05)
all structure
Cancer typeTranslation factorpvaladj.p
LGGEIF3H0.003286336316889410.11
BRCAEIF3H0.02930204031046270.85
PRADEIF3H0.0001046308799718910.0035
CESCEIF3H0.02273134675643230.68
THYMEIF3H0.01697427525114360.53

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Related Drugs


check button Drugs targeting genes involved in this translation factor.
(DrugBank Version 5.1.8 2021-05-08)
UniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases


check button Diseases associated with this translation factor.
(DisGeNet 4.0)
Disease IDDisease Name# PubMedsDisease source
C0009402Colorectal Carcinoma1CTD_human
C0376358Malignant neoplasm of prostate1CTD_human
C2239176Liver carcinoma1CTD_human