Example Fusion Geness

First designed targeted therapy target: BCR-ABL1 (Chronic Myeloid Leukemia, CML)

Driver oncogene in the non-small cell lung cancer (NSCLC): EML4-ALK

The most frequent mutation in the prostate cancer (PRCA): TMPRSS2-ERG

Non-tyrosine kinase group fusion in multiple cancer types (in both adult and pediatric cancers): ETV6-NTRK3

Dominant fusion gene in the Ewing sarcoma: EWSR1-FLI1