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	Gene Summary
	Translation studies in PubMed
	Exon Skipping Events
	Expression
	Expression Regulation
	Associated Genes
	Protein 3D Structure
	Protein-Protein Interaction
	Mutations
	Prognostic Analysis
	Gender Association
	Age Association
	Related Drugs
	Related Diseases

Translation Factor: RRBP1 (NCBI Gene ID:6238)

Gene Summary

Gene Summary

Gene Information	Gene Name: RRBP1
	Gene ID: 6238
	Gene Symbol	RRBP1
	Gene ID	6238
	Gene Name	ribosome binding protein 1
	Synonyms	ES/130\|ES130\|RRp\|hES
	Cytomap	20p12.1
	Type of Gene	protein-coding
	Description	ribosome-binding protein 1180 kDa ribosome receptor homologES/130-related proteinribosome binding protein 1 homolog 180kDa (dog)ribosome receptor protein
	Modification date	20200313
	UniProtAcc	Q9P2E9

Child GO biological process term(s) under GO:0006412

GO ID	GO term
GO:0005840	Ribosome
GO:0006412	Translation

Gene ontology of translaction factor with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Inferred gene age of translation factor.

Gene	Inferred gene age group among (0 - 67.6], (67.6 - 355.7], (355.7 - 733], (733 - 1119.25], >1119.25
RRBP1	(733 - 1119.25]

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Translation Studies in PubMed

We searched PubMed using 'RRBP1[title] AND translation [title] AND human.'

Gene	Title	PMID
RRBP1	La Autoantigen Induces Ribosome Binding Protein 1 (RRBP1) Expression through Internal Ribosome Entry Site (IRES)-Mediated Translation during Cellular Stress Condition	27447629

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Exon Skipping Events

Skipped exons in TCGA and GTEx based on Ensembl gene isoform structure.
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
For more annotations, please visit our ExonSkipDB.

Open reading frame (ORF) analsis of exon skipping events based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ENST	Exon skip start (DNA)	Exon Skip end (DNA)	ORF
ENST00000246043	17596075	17596174	In-frame
ENST00000377813	17596075	17596174	In-frame
ENST00000246043	17596570	17596654	In-frame
ENST00000377813	17596570	17596654	In-frame
ENST00000246043	17597376	17597484	In-frame
ENST00000377813	17597376	17597484	In-frame
ENST00000246043	17599240	17599324	In-frame
ENST00000377813	17599240	17599324	In-frame
ENST00000246043	17600277	17600373	In-frame
ENST00000377813	17600277	17600373	In-frame
ENST00000246043	17601359	17601452	In-frame
ENST00000377813	17601359	17601452	In-frame
ENST00000246043	17602499	17602592	In-frame
ENST00000377813	17602499	17602592	In-frame
ENST00000246043	17605220	17605313	In-frame
ENST00000377813	17605220	17605313	In-frame
ENST00000246043	17607992	17608027	Frame-shift
ENST00000377813	17607992	17608027	Frame-shift
ENST00000246043	17616190	17616309	Frame-shift
ENST00000377813	17616190	17616309	Frame-shift
ENST00000246043	17617221	17617374	In-frame
ENST00000377813	17617221	17617374	In-frame
ENST00000246043	17622441	17622564	In-frame
ENST00000377813	17622441	17622564	In-frame
ENST00000246043	17623623	17623772	Frame-shift
ENST00000377813	17623623	17623772	Frame-shift
ENST00000377813	17639240	17641173	3UTR-3CDS
ENST00000377813	17660643	17660720	3UTR-3UTR

Exon skipping position in the amino acid sequence.

ENST	Exon skip start (DNA)	Exon Skip end (DNA)	Len(transcript seq)	Exon skip start (mRNA)	Exon Skip end (mRNA)	Len(amino acid seq)	Exon skip start (AA)	Exon Skip end (AA)
ENST00000246043	17596075	17596174	4754	3952	4050	1410	1317	1350
ENST00000377813	17596075	17596174	5058	4256	4354	1410	1317	1350
ENST00000246043	17596570	17596654	4754	3868	3951	1410	1289	1317
ENST00000377813	17596570	17596654	5058	4172	4255	1410	1289	1317
ENST00000246043	17597376	17597484	4754	3760	3867	1410	1253	1289
ENST00000377813	17597376	17597484	5058	4064	4171	1410	1253	1289
ENST00000246043	17599240	17599324	4754	3676	3759	1410	1225	1253
ENST00000377813	17599240	17599324	5058	3980	4063	1410	1225	1253
ENST00000246043	17600277	17600373	4754	3580	3675	1410	1193	1225
ENST00000377813	17600277	17600373	5058	3884	3979	1410	1193	1225
ENST00000246043	17601359	17601452	4754	3415	3507	1410	1138	1169
ENST00000377813	17601359	17601452	5058	3719	3811	1410	1138	1169
ENST00000246043	17602499	17602592	4754	3148	3240	1410	1049	1080
ENST00000377813	17602499	17602592	5058	3452	3544	1410	1049	1080
ENST00000246043	17605220	17605313	4754	3055	3147	1410	1018	1049
ENST00000377813	17605220	17605313	5058	3359	3451	1410	1018	1049
ENST00000246043	17617221	17617374	4754	2185	2337	1410	728	779
ENST00000377813	17617221	17617374	5058	2489	2641	1410	728	779
ENST00000246043	17622441	17622564	4754	2062	2184	1410	687	728
ENST00000377813	17622441	17622564	5058	2366	2488	1410	687	728

Potentially (partially) lost protein functional features of UniProt.

UniProtAcc

Exon skip start (AA)

Exon Skip end (AA)

Function feature start (AA)

Function feature end (AA)

Functional feature type

Functional feature desc.

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Expression

Gene expression level across TCGA pancancer

Gene expression level across GTEx pantissue

Expression level of gene isoforms across TCGA pancancer

Expression level of gene isoforms across GTEx pantissue

Cancer(tissue) type-specific expression level of Translation factor using z-score distriution

Differential expression between tumor and matched normal (in the cancer types with more than 10 matched samples)

Cancer type	Translation factor	FC	adj.pval
KICH	RRBP1	-4.71047487512986	0.000287055969238281
KIRC	RRBP1	-1.42449281277031	0.00189590326053014
CHOL	RRBP1	-1.73450384520918	0.0078125
BLCA	RRBP1	-1.67862033374904	0.0493659973144531
BRCA	RRBP1	-1.71274825007363	2.21762214457575e-05

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Expression Regulation

Translation factor expression regulation through miRNA binding

Cancer type

Gene

miRNA

TargetScan binding score (Context++ score percentile)

Coefficient

Pvalue

Translation factor expression regulation through methylation in the promoter of Translation factor

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through methylation in the gene body of Translation factor (positive regulation)

Cancer type

Gene

methyl group b

methyl group a

DEG pval

avg methyl in b

avg methyl in a

avg exp in b

avg exp in a

Translation factor expression regulation through copy number variation of Translation factor

Cancer type	Gene	Coefficient	Pvalue
READ	RRBP1	-0.045319131	0.041802175

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Associated Genes

Strongly correlated genes belong to cellular important gene groups with RRBP1 (coefficient>0.8, pval<0.05, node color based on FC between tumor and matched normal). Significantly associated important genes in the individual cancer types. * Cell metabolism gene: cell metabolism genes from REACTOME (black edge), IUPHAR: drug target genes from IUPHAR (blue edge), Kinase: human kinase genes (brown edge), CGC: cancer gene census genes (orange edge), TSG: tumor suppresor genes (purple edge), Epifactor: epigenetic factors (light blue edge), TF: transcription factors (green)

Cancer type	Gene group	Translation factor	Correlated gene	Coefficient	Pvalue
UVM	IUPHAR	RRBP1	CTSD	0.802766669	3.41E-19

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Protein structure

Protein 3D structure
Visit iCn3D.

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Protein-Protein Interaction

Protein-protein interaction networks
* Overlap between up-regulated DEGs (log2FC<-1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

Overlap between down-regulated DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network (center: Translation factor, node: DEGs, edges: weighted by -log2(adj.P))

* Edge colors based on TCGA cancer types.

* Overlap between DEGs (log2FC>1 and adj.P<0.05) and STRING PPI network per cancer (center: Translation factor, node: DEGs, node color: log2FC, edges: weighted by -log2(adj.P))

Cancer type	Translation factor	Interacting protein coding gene	FC	adj.pval
HNSC	RRBP1	HAL	-2.02383263672592	0.000102781329587742
PRAD	RRBP1	COL6A2	-1.97003212443971	0.000160125183544188
BLCA	RRBP1	COL6A2	-1.76614863858307	0.000164031982421875
COAD	RRBP1	CARNS1	1.47319198283413	0.00028228759765625
HNSC	RRBP1	DET1	1.29447580604041	0.000333792391984389
KIRP	RRBP1	CARNS1	1.18495622593176	0.000471815001219511
KIRC	RRBP1	DET1	-4.72453945863564	0.000707497773404709
LUAD	RRBP1	HAL	1.23118666642251	0.000972928521462759
CHOL	RRBP1	HAL	-2.29076596776084	0.00390625
LIHC	RRBP1	COL6A1	1.05328513585786	0.00576533190924774
BLCA	RRBP1	COL6A1	-2.09013900221882	0.0061798095703125
LIHC	RRBP1	DET1	-1.64899127005206	0.0388472135404142
LUAD	RRBP1	CARNS1	1.50368270944585	0.0474746424607937
BRCA	RRBP1	CARNS1	1.5059922822488	1.01563502960982e-13
THCA	RRBP1	DET1	-1.12898983404918	1.24096187709557e-07
KIRC	RRBP1	HAL	-1.02993783202786	2.39785093662926e-06
BRCA	RRBP1	DET1	-1.68528651411843	2.65458780824788e-13
KIRC	RRBP1	COL6A1	-1.51848046974444	2.90610936482183e-06

Protein-protein interactors with this translation factor (BIOGRID-3.4.160)

PPI interactors with RRBP1

DSTN, Ndc80, ZWINT, CUL3, NDUFA7, CDV3, SCP2, RPS19, ILF3, PPIF, HNRNPM, MRPL53, SRPRB, PIN4, RBMS1, KLF5, RAB8A, CHMP2A, PQBP1, RPL38, HSPA1L, HSBP1, IQCB1, SMAD9, PRKD2, MAP1LC3A, KIAA0101, TARDBP, LGR4, VCP, CUL7, NTRK1, MORC2, RBM8A, BUD31, SMNDC1, EWSR1, TMPO, Eef1a1, Ktn1, Mad2l2, Cdk5rap2, FOXG1, FOXL1, PES1, EMILIN1, EEF1D, KLHL2, TSPYL6, STYX, DLST, PDHA1, TRIM25, YAP1, HNRNPL, ARMC8, APOE, EFTUD2, AGR2, RECQL4, MB21D1, MYC, CDK9, HIST1H4A, HIST1H2BB, BET1, CANX, RAB11A, RAB9A, RPS6, HIST1H3A, FBL, TOMM22, AURKAIP1, KIAA1429, PHB, DISC1, USP14, NR2C2, NHLRC2, CPT1A, HADHB, PGAM5, TOMM5, VDAC2, RHBDD1, RHBDF2, BIRC3, STAU1, WWP2, BRD7, FAM105A, MATR3, SQSTM1, PLEKHA4, HCVgp1, MAP3K14, CEP104, SLC25A6, PTPRB, DCC, MKI67, ATRX, MNX1, RPL10A, RPL8, ANK2, PTPRS, CEP55, SLC44A4, ZNF518A, ZNF562, ZNF513, METTL2A, TMEM87B, FYCO1, BOC, CFAP97, SMARCA4, PLEC, ERICH5, HIST1H2BH, ZNF625, PIK3R4, RAB3GAP2, BIRC6, MYH15, PATL2, DNAH5, E, M, nsp4, nsp6, ORF14, ORF7a, ORF7b, ORF8, S, ST7, LRRC31, FKBP8, GRSF1, MTCH2, PTPN1, SLC25A46, HNRNPH1, LRRC59, E5b, BRD4, Apc2, FBP1, DNAJC1, DNAJC14, DNAJC16, DNAJC25, SEC63, DNAJC2, SPNS1, MAP3K15, DDX58, TRIM7, nsp2, UFL1, DDRGK1, ATP2A1, B3GAT1, BCAP31, CKAP4, DERL1, DHFRL1, ELOVL5, EMD, ERGIC2, GJD3, HSD17B11, HSD3B7, METTL7A, PXMP2, RAB3B, RAB5A, REEP5, RPL31, RPN1, RPN2, SEC61B, SEC62, SERBP1, SSR1, STIM1, STX7, FZR1, WDR5, NAA40, SYNJ2BP, FEM1A, KRT80, DTX3, BTF3, ESR1, ANPEP, TMPRSS11B, CLEC4E, FGD5, CALCOCO2, SIRT6, Wdr82, RB1CC1,

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Mutations

Clinically associated variants from ClinVar.

Gene	Chr	Position	RefSeq	VarSeq	RefSeeq	VarType	Pathogenic	Disease	VarInfo
RRBP1	chr20	17595470	C	T	single_nucleotide_variant	Benign	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
RRBP1	chr20	17596582	C	T	single_nucleotide_variant	Likely_benign	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
RRBP1	chr20	17596586	C	T	single_nucleotide_variant	Benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RRBP1	chr20	17597369	G	A	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RRBP1	chr20	17597382	C	T	single_nucleotide_variant	Benign	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
RRBP1	chr20	17600950	C	T	single_nucleotide_variant	Likely_benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RRBP1	chr20	17600992	G	A	single_nucleotide_variant	Benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RRBP1	chr20	17602103	C	T	single_nucleotide_variant	Benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RRBP1	chr20	17602364	G	A	single_nucleotide_variant	Benign	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
RRBP1	chr20	17606220	C	T	single_nucleotide_variant	Benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RRBP1	chr20	17608139	G	A	single_nucleotide_variant	Benign	not_provided	SO:0001627\|intron_variant	SO:0001627\|intron_variant
RRBP1	chr20	17610512	C	T	single_nucleotide_variant	Benign	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
RRBP1	chr20	17610604	C	T	single_nucleotide_variant	Likely_benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RRBP1	chr20	17617342	G	C	single_nucleotide_variant	Likely_benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RRBP1	chr20	17622495	T	C	single_nucleotide_variant	Benign	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
RRBP1	chr20	17622562	G	A	single_nucleotide_variant	Benign	not_provided	SO:0001819\|synonymous_variant	SO:0001819\|synonymous_variant
RRBP1	chr20	17623770	G	A	single_nucleotide_variant	Likely_benign	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant
RRBP1	chr20	17640801	C	T	single_nucleotide_variant	Benign	not_provided	SO:0001583\|missense_variant	SO:0001583\|missense_variant

nsSNVs with sample frequency (size of circle) from TCGA 33 cancers.

SNVs and Indels

Gene	Cancer type	Chromosome	Start	End	RefSeeq	MutSeq	Mutation type	AAchange	# samples
RRBP1	CESC	chr20	17639864	17639864	T	C	Missense_Mutation		7
RRBP1	ESCA	chr20	17639845	17639845	C	T	Silent		7
RRBP1	KICH	chr20	17639820	17639820	C	T	Missense_Mutation		6
RRBP1	ESCA	chr20	17639867	17639867	C	T	Missense_Mutation		6
RRBP1	LIHC	chr20	17639837	17639837	C	T	Missense_Mutation		6
RRBP1	SARC	chr20	17639887	17639887	G	T	Silent		5
RRBP1	ACC	chr20	17622479	17622479	G	A	Missense_Mutation	p.A283V	4
RRBP1	LIHC	chr20	17639668	17639668	A	G	Silent		3
RRBP1	LIHC	chr20	17622505	17622505	T	-	Frame_Shift_Del	p.K707fs	3
RRBP1	ESCA	chr20	17639941	17639941	A	C	Silent		3
RRBP1	LIHC	chr20	17639820	17639820	C	-	Frame_Shift_Del	p.A445fs	3
RRBP1	ESCA	chr20	17617273	17617273	C	T	Missense_Mutation	p.M329I	3
RRBP1	TGCT	chr20	17639834	17639834	T	C	Missense_Mutation		3
RRBP1	LUAD	chr20	17640864	17640864	G	A	Nonsense_Mutation	p.R97*	3
RRBP1	KICH	chr20	17639786	17639786	T	G	Missense_Mutation		3
RRBP1	HNSC	chr20	17640580	17640580	T	G	Silent		3
RRBP1	CESC	chr20	17639815	17639815	C	T	Silent		3
RRBP1	BRCA	chr20	17640582	17640582	T	G	Missense_Mutation	p.T191P	3
RRBP1	LIHC	chr20	17639714	17639714	T	C	Missense_Mutation		3
RRBP1	ESCA	chr20	17641080	17641080	T	A	Missense_Mutation	p.I25F	3
RRBP1	STAD	chr20	17602500	17602500	C	A	Missense_Mutation	p.Q647H	2
RRBP1	UCEC	chr20	17602338	17602338	G	T	Silent	p.S674	2
RRBP1	CESC	chr20	17640216	17640216	C	T	Missense_Mutation		2
RRBP1	PCPG	chr20	17614233	17614233	G	A	Missense_Mutation		2
RRBP1	UVM	chr20	17639295	17639295	T	C	Missense_Mutation		2
RRBP1	STAD	chr20	17601390	17601390	C	A	Missense_Mutation	p.K726N	2
RRBP1	ESCA	chr20	17641107	17641107	C	A	Nonsense_Mutation	p.G16*	2
RRBP1	UCEC	chr20	17605248	17605248	C	A	Missense_Mutation	p.E607D	2
RRBP1	LIHC	chr20	17596122	17596122	G	A	Missense_Mutation		2
RRBP1	LUAD	chr20	17600359	17600359	C	T	Silent	p.T1198T	2
RRBP1	KICH	chr20	17639850	17639850	C	T	Missense_Mutation		2
RRBP1	UCEC	chr20	17606198	17606198	C	T	Missense_Mutation	p.E572K	2
RRBP1	LIHC	chr20	17639804	17639804	T	C	Missense_Mutation		2
RRBP1	CESC	chr20	17639306	17639306	G	T	Missense_Mutation		2
RRBP1	CESC	chr20	17600347	17600347	C	A	Missense_Mutation		2
RRBP1	UVM	chr20	17639295	17639295	T	C	Missense_Mutation	p.K620E	2
RRBP1	LIHC	chr20	17639452	17639452	C	-	Frame_Shift_Del	p.G567fs	2
RRBP1	STAD	chr20	17601385	17601385	C	T	Missense_Mutation	p.G728D	2
RRBP1	UCEC	chr20	17616305	17616305	C	T	Missense_Mutation	p.R348Q	2
RRBP1	LIHC	chr20	17639516	17639516	T	A	Missense_Mutation		2
RRBP1	STAD	chr20	17617341	17617341	C	T	Missense_Mutation	p.G307R	2
RRBP1	THYM	chr20	17602136	17602136	C	T	Silent		2
RRBP1	UCEC	chr20	17622506	17622506	T	G	Missense_Mutation	p.K274T	2
RRBP1	STAD	chr20	17641141	17641141	G	A	Silent		2
RRBP1	LIHC	chr20	17640503	17640503	T	-	Frame_Shift_Del	p.N217fs	2
RRBP1	LIHC	chr20	17639790	17639790	C	T	Missense_Mutation		2
RRBP1	UCEC	chr20	17623773	17623773	C	T	Splice_Site	e3-1	2
RRBP1	CESC	chr20	17639699	17639699	G	A	Missense_Mutation		2
RRBP1	PRAD	chr20	17622555	17622555	T	A	Nonsense_Mutation	p.K691*	2
RRBP1	STAD	chr20	17640852	17640852	G	A	Missense_Mutation		2
RRBP1	UCEC	chr20	17594840	17594840	C	T	Missense_Mutation	p.G974D	2
RRBP1	BRCA	chr20	17639834	17639834	T	C	Missense_Mutation	p.K440R	2
RRBP1	LUAD	chr20	17600972	17600972	A	C	Missense_Mutation	p.L1184R	2
RRBP1	STAD	chr20	17641004	17641004	G	A	Missense_Mutation	p.A50V	2
RRBP1	ESCA	chr20	17640489	17640489	C	A	Missense_Mutation		2
RRBP1	KIRC	chr20	17641122	17641122	C	T	Missense_Mutation	p.V11I	2
RRBP1	UCEC	chr20	17639257	17639257	C	A	Missense_Mutation	p.K202N	2
RRBP1	UCEC	chr20	17596647	17596647	G	A	Missense_Mutation	p.T859M	2
RRBP1	BRCA	chr20	17640650	17640650	G	T	Missense_Mutation	p.A168D	2
RRBP1	STAD	chr20	17640875	17640875	G	C	Missense_Mutation	p.T93S	2
RRBP1	THYM	chr20	17608289	17608289	G	A	Missense_Mutation		2
RRBP1	ESCA	chr20	17599256	17599256	G	A	Silent		2
RRBP1	UCEC	chr20	17639428	17639428	A	G	Silent	p.S575	2
RRBP1	CESC	chr20	17596576	17596576	C	G	Missense_Mutation		2
RRBP1	LIHC	chr20	17640808	17640808	G	-	Frame_Shift_Del	p.P115fs	2
RRBP1	ESCA	chr20	17639256	17639256	T	A	Nonsense_Mutation	p.K633*	2
RRBP1	HNSC	chr20	17600950	17600950	C	T	Silent	p.S1191S	2
RRBP1	UCEC	chr20	17597404	17597404	C	T	Silent	p.A847	2
RRBP1	BRCA	chr20	17641006	17641006	C	T	Missense_Mutation	p.M49I	2
RRBP1	UCEC	chr20	17639669	17639669	G	A	Missense_Mutation	p.A495V	2
RRBP1	LIHC	chr20	17601442	17601442	A	G	Missense_Mutation		2
RRBP1	STAD	chr20	17640852	17640852	G	A	Missense_Mutation	p.R101W	2
RRBP1	ESCA	chr20	17640489	17640489	C	A	Missense_Mutation	p.A222S	2
RRBP1	THYM	chr20	17608180	17608180	G	A	Missense_Mutation		2
RRBP1	UCEC	chr20	17600359	17600359	C	T	Silent	p.T765	2
RRBP1	SKCM	chr20	17614116	17614116	G	A	Silent	p.L867L	2
RRBP1	KIRC	chr20	17595443	17595443	T	C	Missense_Mutation	p.Q1378R	2
RRBP1	UCEC	chr20	17640970	17640970	C	A	Missense_Mutation	p.K61N	2
RRBP1	ACC	chr20	17617312	17617312	C	A	Silent	p.V316V	2
RRBP1	STAD	chr20	17607995	17607995	A	G	Silent	p.T554T	2
RRBP1	STAD	chr20	17614161	17614161	G	A	Missense_Mutation	p.R419W	2
RRBP1	UCEC	chr20	17600998	17600998	C	T	Silent	p.K742	2
RRBP1	CESC	chr20	17622492	17622492	C	T	Missense_Mutation		2
RRBP1	PAAD	chr20	17610570	17610570	G	A	Missense_Mutation	p.R883C	2
RRBP1	SKCM	chr20	17614117	17614117	G	A	Silent	p.V866V	2
RRBP1	ESCA	chr20	17641080	17641080	T	A	Missense_Mutation		2
RRBP1	UCS	chr20	17640992	17640992	T	C	Missense_Mutation	p.H54R	2
RRBP1	ACC	chr20	17602360	17602360	G	T	Missense_Mutation	p.P667Q	2
RRBP1	COAD	chr20	17639909	17639910	-	C	Intron	.	2
RRBP1	ESCA	chr20	17617273	17617273	C	T	Missense_Mutation	p.M762I	1
RRBP1	HNSC	chr20	17610502	17610502	G	A	Silent		1
RRBP1	THYM	chr20	17608289	17608289	G	A	Missense_Mutation	p.R497C	1
RRBP1	HNSC	chr20	17600950	17600950	C	T	Silent	p.S758S	1
RRBP1	LIHC	chr20	17614246	17614246	C	A	Missense_Mutation		1
RRBP1	BLCA	chr20	17599273	17599273	C	T	Missense_Mutation		1
RRBP1	LUAD	chr20	17600359	17600359	C	T	Silent	p.T765T	1
RRBP1	SKCM	chr20	17614117	17614117	G	A	Silent	p.V433V	1
RRBP1	BLCA	chr20	17602402	17602402	A	G	Missense_Mutation	p.L1086P	1
RRBP1	SKCM	chr20	17640802	17640802	G	A	Silent	p.I117I	1
RRBP1	CESC	chr20	17596583	17596583	G	A	Silent	p.A1313	1
RRBP1	SKCM	chr20	17623740	17623740	G	A	Missense_Mutation	p.P649S	1
RRBP1	ESCA	chr20	17599256	17599256	G	A	Silent	p.S815S	1
RRBP1	STAD	chr20	17640808	17640809	-	G	Frame_Shift_Ins	p.P115fs	1
RRBP1	KIRC	chr20	17640771	17640771	G	A	Missense_Mutation	p.P128S	1
RRBP1	LIHC	chr20	17616198	17616198	C	A	Nonsense_Mutation	p.E817*	1
RRBP1	LIHC	chr20	17610552	17610552	G	-	Frame_Shift_Del	p.R889fs	1
RRBP1	BLCA	chr20	17606166	17606166	C	T	Silent	p.V1015V	1
RRBP1	LUAD	chr20	17616230	17616230	C	A	Missense_Mutation	p.R806L	1
RRBP1	SARC	chr20	17617223	17617223	T	A	Missense_Mutation		1
RRBP1	COAD	chr20	17640269	17640270	-	C	Intron	.	1
RRBP1	GBM	chr20	17639349	17639349	A	G	Missense_Mutation		1
RRBP1	THCA	chr20	17639352	17639352	C	A	Nonsense_Mutation	p.E601*	1
RRBP1	STAD	chr20	17641141	17641141	G	A	Silent	p.Y4Y	1
RRBP1	HNSC	chr20	17610538	17610538	G	A	Silent		1
RRBP1	THYM	chr20	17608180	17608180	G	A	Missense_Mutation	p.A533V	1
RRBP1	HNSC	chr20	17623695	17623695	C	T	Missense_Mutation	p.E231K	1
RRBP1	LIHC	chr20	17640866	17640866	A	G	Missense_Mutation		1
RRBP1	BLCA	chr20	17639309	17639309	C	A	Missense_Mutation		1
RRBP1	CESC	chr20	17640013	17640013	T	C	Silent		1
RRBP1	LUAD	chr20	17602407	17602407	C	T	Silent	p.E651E	1
RRBP1	SKCM	chr20	17640672	17640672	G	A	Nonsense_Mutation	p.Q161X	1
RRBP1	BLCA	chr20	17602401	17602401	C	A	Silent	p.L1086L	1
RRBP1	CESC	chr20	17640494	17640494	C	T	Missense_Mutation		1
RRBP1	PCPG	chr20	17614233	17614233	G	A	Missense_Mutation	p.R395W	1
RRBP1	SKCM	chr20	17640960	17640960	T	C	Missense_Mutation	p.T65A	1
RRBP1	CESC	chr20	17606199	17606199	G	T	Silent	p.I1004	1
RRBP1	SKCM	chr20	17596138	17596138	C	T	Missense_Mutation	p.E1330K	1
RRBP1	ESCA	chr20	17640755	17640755	G	A	Missense_Mutation	p.A133V	1
RRBP1	STAD	chr20	17622546	17622547	-	GGTC	Frame_Shift_Ins	p.P261fs	1
RRBP1	KIRC	chr20	17639475	17639475	C	-	Frame_Shift_Del	p.V560fs	1
RRBP1	UVM	chr20	17639295	17639295	T	C	Missense_Mutation	p.K190E	1
RRBP1	LIHC	chr20	17639251	17639251	T	-	Frame_Shift_Del	p.K634fs	1
RRBP1	ACC	chr20	17622479	17622479	G	A	Missense_Mutation	p.A716V	1
RRBP1	BLCA	chr20	17599273	17599273	C	T	Missense_Mutation	p.E810K	1
RRBP1	SARC	chr20	17640808	17640808	G	-	Frame_Shift_Del		1
RRBP1	COAD	chr20	17640300	17640300	C	-	Intron	.	1
RRBP1	STAD	chr20	17617252	17617252	G	A	Silent	p.H336H	1
RRBP1	GBM	chr20	17639438	17639438	C	T	Missense_Mutation		1
RRBP1	THYM	chr20	17639894	17639894	T	C	Missense_Mutation		1
RRBP1	ESCA	chr20	17614177	17614177	C	T	Silent		1
RRBP1	STAD	chr20	17614257	17614257	G	A	Splice_Site	p.Q820_splice	1
RRBP1	HNSC	chr20	17614170	17614170	C	T	Missense_Mutation		1
RRBP1	BLCA	chr20	17600979	17600979	C	T	Missense_Mutation		1
RRBP1	LUAD	chr20	17622538	17622538	C	T	Silent	p.A263A	1
RRBP1	SKCM	chr20	17639691	17639691	G	A	Nonsense_Mutation	p.Q488*	1
RRBP1	BLCA	chr20	17639291	17639291	T	A	Missense_Mutation	p.Q621L	1
RRBP1	PCPG	chr20	17614233	17614233	G	A	Missense_Mutation	p.R828W	1
RRBP1	SKCM	chr20	17640885	17640885	G	C	Missense_Mutation	p.P90A	1
RRBP1	COAD	chr20	17597383	17597383	G	A	Silent	p.P854P	1
RRBP1	SKCM	chr20	17640672	17640672	G	A	Nonsense_Mutation	p.Q161*	1
RRBP1	ESCA	chr20	17614177	17614177	C	T	Silent	p.R413R	1
RRBP1	STAD	chr20	17614257	17614257	G	A	Nonsense_Mutation		1
RRBP1	KIRP	chr20	17602147	17602148	GT	-	Frame_Shift_Del	p.691_691del	1
RRBP1	THYM	chr20	17601366	17601366	G	T	Silent	p.L734L	1
RRBP1	LIHC	chr20	17640671	17640671	T	C	Missense_Mutation		1
RRBP1	LIHC	chr20	17639417	17639417	T	-	Frame_Shift_Del	p.K579fs	1
RRBP1	ACC	chr20	17617312	17617312	C	A	Silent	p.V749V	1
RRBP1	BLCA	chr20	17639309	17639309	C	A	Missense_Mutation	p.S185I	1
RRBP1	LUAD	chr20	17602407	17602407	C	T	Silent	p.E1084E	1
RRBP1	SARC	chr20	17602363	17602363	T	C	Missense_Mutation		1
RRBP1	COAD	chr20	17597451	17597451	C	T	Missense_Mutation	p.V832I	1
RRBP1	GBM	chr20	17640970	17640970	C	T	Silent		1
RRBP1	THYM	chr20	17641023	17641023	T	C	Missense_Mutation		1
RRBP1	STAD	chr20	17639350	17639351	CT	-	Frame_Shift_Del	p.E601fs	1
RRBP1	HNSC	chr20	17599307	17599307	T	C	Silent	p.L1231L	1
RRBP1	KICH	chr20	17639816	17639816	T	G	Missense_Mutation		1
RRBP1	LIHC	chr20	17616198	17616198	C	A	Nonsense_Mutation	p.E384X	1
RRBP1	BLCA	chr20	17602568	17602568	G	C	Missense_Mutation		1
RRBP1	CESC	chr20	17639856	17639856	C	T	Missense_Mutation		1
RRBP1	LUSC	chr20	17641085	17641085	A	C	Missense_Mutation	p.I23S	1
RRBP1	SKCM	chr20	17639692	17639692	G	A	Silent	p.N487N	1
RRBP1	BLCA	chr20	17599273	17599273	C	T	Missense_Mutation	p.E1243K	1
RRBP1	CESC	chr20	17596583	17596583	G	A	Silent	p.A1313A	1
RRBP1	PRAD	chr20	17616231	17616231	G	A	Missense_Mutation	p.R373W	1
RRBP1	COAD	chr20	17600349	17600349	C	T	Missense_Mutation	p.E769K	1
RRBP1	SKCM	chr20	17617376	17617377	-	G	Splice_Site		1
RRBP1	ESCA	chr20	17639256	17639256	T	A	Nonsense_Mutation	p.K203X	1
RRBP1	TGCT	chr20	17640067	17640067	G	T	Silent		1
RRBP1	KIRP	chr20	17640031	17640031	C	A	Silent		1
RRBP1	UCEC	chr20	17600998	17600998	C	T	Silent	p.K742K	1
RRBP1	LIHC	chr20	17640180	17640180	C	-	Frame_Shift_Del	p.A325fs	1
RRBP1	ACC	chr20	17617260	17617260	G	T	Silent	p.R767R	1
RRBP1	BLCA	chr20	17600979	17600979	C	T	Missense_Mutation	p.E749K	1
RRBP1	LUAD	chr20	17608196	17608196	C	G	Missense_Mutation	p.E961Q	1
RRBP1	SARC	chr20	17599291	17599291	G	T	Missense_Mutation		1
RRBP1	DLBC	chr20	17602571	17602571	A	G	Missense_Mutation	p.C624R	1
RRBP1	GBM	chr20	17608297	17608297	G	A	Missense_Mutation		1
RRBP1	SKCM	chr20	17602182	17602182	G	A	Missense_Mutation	p.S1112F	1
RRBP1	STAD	chr20	17599388	17599388	G	A	Translation_Start_Site		1
RRBP1	HNSC	chr20	17610538	17610538	G	A	Silent	p.H893H	1
RRBP1	LIHC	chr20	17640636	17640636	C	A	Missense_Mutation	p.A173S	1
RRBP1	BLCA	chr20	17623695	17623695	C	T	Missense_Mutation		1
RRBP1	CESC	chr20	17606199	17606199	G	T	Silent		1
RRBP1	LUSC	chr20	17594839	17594839	G	A	Silent	p.G974G	1
RRBP1	SKCM	chr20	17597384	17597384	G	A	Missense_Mutation	p.P1287L	1
RRBP1	BLCA	chr20	17639309	17639309	C	A	Missense_Mutation	p.S615I	1
RRBP1	CESC	chr20	17640441	17640441	G	A	Nonsense_Mutation		1
RRBP1	PRAD	chr20	17622555	17622555	T	A	Nonsense_Mutation	p.K258X	1
RRBP1	COAD	chr20	17601423	17601423	G	A	Silent	p.S715S	1
RRBP1	LGG	chr20	17622477	17622477	C	T	Missense_Mutation	p.A717T	1
RRBP1	UCEC	chr20	17597404	17597404	C	T	Silent	p.A847A	1
RRBP1	ACC	chr20	17639980	17639980	T	-	Frame_Shift_Del	p.K391fs	1
RRBP1	BLCA	chr20	17602568	17602568	G	C	Missense_Mutation	p.L625V	1
RRBP1	SARC	chr20	17602363	17602363	T	C	Missense_Mutation	p.H1099R	1
RRBP1	ESCA	chr20	17599256	17599256	G	A	Silent	p.S1248	1
RRBP1	STAD	chr20	17640807	17640808	-	G	Frame_Shift_Ins	p.I116fs	1
RRBP1	GBM	chr20	17596652	17596652	C	A	Silent		1
RRBP1	THYM	chr20	17602362	17602362	G	T	Missense_Mutation		1
RRBP1	SKCM	chr20	17596615	17596615	C	T	Missense_Mutation	p.D1303N	1
RRBP1	STAD	chr20	17601012	17601012	G	A	Missense_Mutation	p.R738W	1
RRBP1	HNSC	chr20	17614170	17614170	C	T	Missense_Mutation	p.E849K	1
RRBP1	LIHC	chr20	17596112	17596112	T	C	Silent	p.L905L	1
RRBP1	BLCA	chr20	17617277	17617277	C	T	Missense_Mutation		1
RRBP1	LUSC	chr20	17610501	17610501	C	A	Nonsense_Mutation	p.E473*	1
RRBP1	SKCM	chr20	17639518	17639518	G	A	Silent	p.I545I	1
RRBP1	BLCA	chr20	17600979	17600979	C	T	Missense_Mutation	p.E1182K	1
RRBP1	CESC	chr20	17622492	17622492	C	T	Missense_Mutation	p.E712K	1
RRBP1	LIHC	chr20	17640270	17640270	C	-	Frame_Shift_Del	p.A295fs	1
RRBP1	COAD	chr20	17602110	17602110	G	A	Missense_Mutation	p.A703V	1
RRBP1	ESCA	chr20	17614113	17614113	G	A	Nonsense_Mutation	p.Q435X	1
RRBP1	TGCT	chr20	17639876	17639876	T	G	Missense_Mutation		1
RRBP1	LGG	chr20	17602584	17602584	C	T	Silent	p.S1052S	1
RRBP1	LIHC	chr20	17639507	17639507	T	-	Frame_Shift_Del	p.K549fs	1
RRBP1	LIHC	chr20	17639803	17639803	C	T	Silent		1
RRBP1	BLCA	chr20	17640976	17640976	C	G	Missense_Mutation		1
RRBP1	SKCM	chr20	17617376	17617377	-	G	Splice_Site	.	1
RRBP1	ESCA	chr20	17608209	17608212	TCTC	-	Frame_Shift_Del	p.R956fs	1
RRBP1	HNSC	chr20	17602571	17602571	A	G	Missense_Mutation		1
RRBP1	THYM	chr20	17639492	17639492	G	C	Missense_Mutation		1
RRBP1	SKCM	chr20	17610549	17610549	C	T	Missense_Mutation	p.E890K	1
RRBP1	STAD	chr20	17601380	17601380	C	T	Missense_Mutation	p.A730T	1
RRBP1	LIHC	chr20	17596120	17596120	C	A	Missense_Mutation	p.G903C	1
RRBP1	BLCA	chr20	17622471	17622471	C	T	Missense_Mutation		1
RRBP1	CESC	chr20	17602103	17602103	C	T	Silent		1
RRBP1	OV	chr20	17554168	17554168	C	G	Missense_Mutation	p.V582L	1
RRBP1	SKCM	chr20	17639601	17639601	G	A	Nonsense_Mutation	p.Q518*	1
RRBP1	BLCA	chr20	17602568	17602568	G	C	Missense_Mutation	p.L1058V	1
RRBP1	CESC	chr20	17639699	17639699	G	A	Missense_Mutation	p.A485V	1
RRBP1	LIHC	chr20	17640476	17640476	G	-	Frame_Shift_Del	p.P226fs	1
RRBP1	READ	chr20	17640316	17640316	C	-	Intron	.	1
RRBP1	COAD	chr20	17608154	17608154	C	T	Missense_Mutation	p.V542I	1
RRBP1	STAD	chr20	17639350	17639351	CT	-	Frame_Shift_Del		1
RRBP1	ESCA	chr20	17599256	17599256	G	A	Silent	p.S1248S	1
RRBP1	TGCT	chr20	17639827	17639827	G	A	Silent		1
RRBP1	LGG	chr20	17608171	17608171	G	A	Missense_Mutation	p.A969V	1
RRBP1	LIHC	chr20	17639813	17639813	T	-	Frame_Shift_Del	p.N447fs	1
RRBP1	HNSC	chr20	17623689	17623689	C	T	Missense_Mutation	p.E666K	1
RRBP1	LIHC	chr20	17623651	17623651	A	G	Silent		1
RRBP1	BLCA	chr20	17595505	17595505	C	G	Missense_Mutation		1
RRBP1	LUAD	chr20	17622538	17622538	C	T	Silent	p.A696A	1
RRBP1	SKCM	chr20	17623740	17623740	G	A	Missense_Mutation	p.P216S	1
RRBP1	ESCA	chr20	17614113	17614113	G	A	Nonsense_Mutation	p.Q868*	1
RRBP1	SKCM	chr20	17601382	17601382	G	A	Missense_Mutation	p.A1162V	1
RRBP1	SKCM	chr20	17622479	17622479	G	T	Missense_Mutation	p.A716E	1
RRBP1	STAD	chr20	17617291	17617291	C	T	Silent	p.T323T	1
RRBP1	KIRC	chr20	17641024	17641024	G	T	Silent	p.A43A	1
RRBP1	LIHC	chr20	17640671	17640671	T	C	Missense_Mutation	p.Q161R	1
RRBP1	BLCA	chr20	17640924	17640924	C	G	Missense_Mutation		1
RRBP1	OV	chr20	17602521	17602521	T	C	Silent	p.E640	1
RRBP1	LIHC	chr20	17640971	17640971	T	-	Frame_Shift_Del	p.K62fs	1
RRBP1	BLCA	chr20	17600958	17600958	C	T	Missense_Mutation	p.E1189K	1
RRBP1	COAD	chr20	17614129	17614129	G	A	Silent	p.F429F	1
RRBP1	STAD	chr20	17614257	17614257	G	A	Nonsense_Mutation	p.Q387X	1
RRBP1	ESCA	chr20	17608209	17608212	TCTC	-	Frame_Shift_Del	p.ER955fs	1
RRBP1	TGCT	chr20	17617269	17617269	C	T	Missense_Mutation	p.A764T	1
RRBP1	LGG	chr20	17639269	17639271	CTT	-	In_Frame_Del	p.K628del	1
RRBP1	STAD	chr20	17610604	17610604	C	T	Silent	p.A438A	1
RRBP1	HNSC	chr20	17623689	17623689	C	T	Missense_Mutation		1
RRBP1	THYM	chr20	17599282	17599282	C	T	Missense_Mutation		1
RRBP1	LIHC	chr20	17639846	17639846	T	G	Missense_Mutation		1
RRBP1	BLCA	chr20	17602401	17602401	C	A	Silent		1
RRBP1	LUAD	chr20	17639463	17639463	T	A	Missense_Mutation	p.T564S	1
RRBP1	SKCM	chr20	17601382	17601382	G	A	Missense_Mutation	p.A729V	1
RRBP1	OV	chr20	17639676	17639676	C	T	Missense_Mutation	p.E493K	1
RRBP1	SKCM	chr20	17595518	17595518	A	T	Missense_Mutation	p.L1353Q	1
RRBP1	CESC	chr20	17640216	17640216	C	T	Missense_Mutation	p.E313K	1
RRBP1	SKCM	chr20	17614161	17614161	G	A	Missense_Mutation	p.R852W	1
RRBP1	ESCA	chr20	17608209	17608212	TCTC	-	Frame_Shift_Del		1
RRBP1	STAD	chr20	17610604	17610604	C	T	Missense_Mutation	p.R24H	1
RRBP1	KIRC	chr20	17608188	17608188	C	A	Silent	p.L530L	1
RRBP1	LIHC	chr20	17596122	17596122	G	A	Missense_Mutation	p.A902V	1
RRBP1	BLCA	chr20	17640976	17640976	C	G	Missense_Mutation	p.K59N	1
RRBP1	LIHC	chr20	17617338	17617338	C	-	Frame_Shift_Del	p.E741fs	1
RRBP1	BLCA	chr20	17639586	17639586	C	T	Missense_Mutation	p.E523K	1
RRBP1	SARC	chr20	17602156	17602156	G	T	Missense_Mutation		1
RRBP1	COAD	chr20	17616199	17616199	C	T	Silent	p.V383V	1
RRBP1	ESCA	chr20	17639256	17639256	T	A	Nonsense_Mutation		1
RRBP1	THCA	chr20	17596599	17596599	C	A	Missense_Mutation		1
RRBP1	STAD	chr20	17622545	17622546	-	GGTC	Frame_Shift_Ins	p.P261fs	1
RRBP1	HNSC	chr20	17600950	17600950	C	T	Silent		1
RRBP1	HNSC	chr20	17610502	17610502	G	A	Silent	p.A905A	1
RRBP1	LIHC	chr20	17639707	17639707	A	G	Silent		1
RRBP1	BLCA	chr20	17602402	17602402	A	G	Missense_Mutation		1
RRBP1	LUAD	chr20	17602515	17602516	AG	-	Frame_Shift_Del	p.S1075fs	1
RRBP1	SKCM	chr20	17595518	17595518	A	T	Missense_Mutation	p.L920Q	1
RRBP1	BLCA	chr20	17596589	17596589	G	C	Silent	p.L1311L	1
RRBP1	CESC	chr20	17639378	17639378	G	T	Missense_Mutation		1
RRBP1	PAAD	chr20	17610570	17610570	G	A	Missense_Mutation		1
RRBP1	SKCM	chr20	17608260	17608260	G	A	Silent	p.L939L	1
RRBP1	CESC	chr20	17640441	17640441	G	A	Nonsense_Mutation	p.Q238*	1
RRBP1	ESCA	chr20	17639875	17639875	C	T	Silent		1
RRBP1	STAD	chr20	17617252	17617252	G	A	Translation_Start_Site		1
RRBP1	LIHC	chr20	17596122	17596122	G	A	Missense_Mutation	p.A1335V	1
RRBP1	LIHC	chr20	17640172	17640172	G	A	Silent		1
RRBP1	LIHC	chr20	17623704	17623704	C	-	Frame_Shift_Del	p.V661fs	1
RRBP1	BLCA	chr20	17617277	17617277	C	T	Missense_Mutation	p.R761H	1
RRBP1	SARC	chr20	17639512	17639512	G	T	Silent		1
RRBP1	COAD	chr20	17623745	17623745	T	C	Missense_Mutation	p.Y214C	1
RRBP1	ESCA	chr20	17641107	17641107	C	A	Nonsense_Mutation		1
RRBP1	THCA	chr20	17610535	17610535	C	T	Silent		1
RRBP1	HNSC	chr20	17600992	17600992	G	A	Silent		1
RRBP1	THYM	chr20	17639980	17639980	T	C	Silent		1
RRBP1	HNSC	chr20	17623689	17623689	C	T	Missense_Mutation	p.E233K	1
RRBP1	LIHC	chr20	17596120	17596120	C	A	Missense_Mutation		1
RRBP1	BLCA	chr20	17639291	17639291	T	A	Missense_Mutation		1
RRBP1	CESC	chr20	17596583	17596583	G	A	Silent		1
RRBP1	LUAD	chr20	17640883	17640883	G	-	Frame_Shift_Del	p.P90fs	1
RRBP1	SKCM	chr20	17614116	17614116	G	A	Silent	p.L434L	1
RRBP1	BLCA	chr20	17595505	17595505	C	G	Missense_Mutation	p.K1357N	1
RRBP1	SKCM	chr20	17610507	17610507	C	T	Missense_Mutation	p.D904N	1
RRBP1	CESC	chr20	17596576	17596576	C	G	Missense_Mutation	p.E1316Q	1
RRBP1	STAD	chr20	17601408	17601410	CTC	-	In_Frame_Del	p.720_721EQ>A	1
RRBP1	KIRC	chr20	17600277	17600277	C	T	Splice_Site		1
RRBP1	LIHC	chr20	17639516	17639516	T	A	Missense_Mutation	p.Q546L	1
RRBP1	LIHC	chr20	17595466	17595466	C	A	Silent		1
RRBP1	LIHC	chr20	17639817	17639817	G	-	Frame_Shift_Del	p.Q446fs	1
RRBP1	BLCA	chr20	17640924	17640924	C	G	Missense_Mutation	p.E77Q	1
RRBP1	LIHC	chr20	17616198	17616198	C	A	Nonsense_Mutation		1
RRBP1	SARC	chr20	17639267	17639267	G	T	Missense_Mutation		1
RRBP1	STAD	chr20	17617289	17617289	G	A	Missense_Mutation	p.A324V	1
RRBP1	GBM	chr20	17608230	17608230	C	A	Missense_Mutation		1
RRBP1	THCA	chr20	17596599	17596599	C	A	Missense_Mutation	p.R1308L	1

Copy number variation (CNV) of RRBP1
* Click on the image to open the original image in a new window.

Fusion gene breakpoints (product of the structural variants (SVs)) across RRBP1
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion genes with this translation factor from FusionGDB2.0.

FusionGDB2 ID	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
85013	N/A	FN121890	ANKRD30A	chr10	37545209	+	RRBP1	chr20	17654092	-
85013	CESC	TCGA-EA-A4BA-01A	BTBD3	chr20	11871602	+	RRBP1	chr20	17623772	-
85013	N/A	BG004426	C1orf132	chr1	207990466	+	RRBP1	chr20	17595415	-
85013	Non-Cancer	269N	CALR	chr19	13051701	+	RRBP1	chr20	17599324	-
85013	BLCA	TCGA-GU-A764-01A	CC2D1A	chr19	14034624	+	RRBP1	chr20	17660720	-
85013	LUAD	TCGA-49-4512-01A	CHID1	chr11	910775	-	RRBP1	chr20	17610606	-
85013	SARC	TCGA-X9-A971-01A	COL3A1	chr2	189859057	+	RRBP1	chr20	17639251	-
85013	N/A	AA977483	CRY1	chr12	107446254	-	RRBP1	chr20	17639526	+
85013	N/A	BG013671	CSH1	chr17	61972346	-	RRBP1	chr20	17640824	-
85013	LGG	TCGA-E1-A7Z2-01A	DZANK1	chr20	18393290	-	RRBP1	chr20	17623772	-
85013	STAD	TCGA-HU-A4GN-01A	HLCS	chr21	38334336	-	RRBP1	chr20	17641173	-
85013	BLCA	TCGA-FD-A3B8-01A	KIF16B	chr20	16474936	-	RRBP1	chr20	17641173	-
85013	LUAD	TCGA-44-3919-01A	KIF16B	chr20	16506737	-	RRBP1	chr20	17641173	-
85013	STAD	TCGA-VQ-A922	KIF16B	chr20	16553873	-	RRBP1	chr20	17660720	-
85013	N/A	AI051667	RAB11B	chr19	8468998	-	RRBP1	chr20	17621075	+
85013	STAD	TCGA-FP-8211-01A	RPS14	chr5	149827221	-	RRBP1	chr20	17595519	-
97972	.	.	RRBP1	chr20	17601015	-	ALK	chr2	17601015	-
95236	PRAD	TCGA-CH-5745-01A	RRBP1	chr20	17594323	-	ARFGEF2	chr20	47615777	+
87261	N/A	BF848903	RRBP1	chr20	17660713	+	BCL6	chr3	187447224	-
78296	OV	TCGA-24-2020	RRBP1	chr20	17660643	-	BFSP1	chr20	17505553	-
78296	OV	TCGA-24-2020-01A	RRBP1	chr20	17660644	-	BFSP1	chr20	17505553	-
78296	OV	TCGA-24-2020-01A	RRBP1	chr20	17660644	-	BFSP1	chr20	17541223	-
78296	OV	TCGA-24-2020-01A	RRBP1	chr20	17660644	-	BFSP1	chr20	17541428	-
78296	OV	TCGA-24-2020-01A	RRBP1	chr20	17660644	-	BFSP1	chr20	17543740	-
78296	OV	TCGA-24-2020-01A	RRBP1	chr20	17662673	-	BFSP1	chr20	17505553	-
78296	OV	TCGA-24-2020-01A	RRBP1	chr20	17662673	-	BFSP1	chr20	17543740	-
98915	LUAD	TCGA-49-4512-01A	RRBP1	chr20	17614105	-	CHID1	chr11	893519	-
89816	Non-Cancer	TCGA-CG-5734-11A	RRBP1	chr20	17640374	-	GRK5	chr10	120967304	+
78296	N/A	CA487475	RRBP1	chr20	17605223	-	LIPE-AS1	chr19	43059918	-
101074	PRAD	TCGA-HC-7736	RRBP1	chr20	17662672	-	MACROD2	chr20	15843389	+
101074	PRAD	TCGA-HC-7736-01A	RRBP1	chr20	17660644	-	MACROD2	chr20	15843390	+
101074	PRAD	TCGA-HC-7736-01A	RRBP1	chr20	17662673	-	MACROD2	chr20	15843390	+
78296	STAD	TCGA-BR-8590-01A	RRBP1	chr20	17639241	-	OVOL2	chr20	18005596	-
78296	STAD	TCGA-BR-8590-01A	RRBP1	chr20	17639250	-	OVOL2	chr20	18005596	-
85011	STAD	TCGA-VQ-A922	RRBP1	chr20	17596075	-	PCSK2	chr20	17462228	+
85011	STAD	TCGA-VQ-A922-01A	RRBP1	chr20	17596078	-	PCSK2	chr20	17462227	+
85011	STAD	TCGA-VQ-A922-01A	RRBP1	chr20	17596571	-	PCSK2	chr20	17462229	+
81391	BRCA	TCGA-C8-A12K-01A	RRBP1	chr20	17660644	-	RBBP8	chr18	20491563	+
85013	N/A	BG984836	RRBP1	chr20	17594690	-	RRBP1	chr20	17615002	-
85013	N/A	CB048557	RRBP1	chr20	17596132	-	RRBP1	chr20	17641036	-
85013	N/A	CB048558	RRBP1	chr20	17641036	+	RRBP1	chr20	17596132	+
92784	N/A	BC046249	RRBP1	chr20	17600318	-	RUFY1	chr5	178977829	+
83880	COAD	TCGA-A6-2675-01A	RRBP1	chr20	17639241	-	SNTA1	chr20	32026832	-
94363	STAD	TCGA-CG-4443	RRBP1	chr20	17662672	-	SNX5	chr20	17937681	-
94363	STAD	TCGA-CG-4443-01A	RRBP1	chr20	17660644	-	SNX5	chr20	17937681	-
101588	LUAD	TCGA-50-5072-01A	RRBP1	chr20	17614105	-	TASP1	chr20	13398168	-
101588	LUAD	TCGA-91-6831	RRBP1	chr20	17614104	-	TASP1	chr20	13398168	-
102830	N/A	AA429648	RRBP1	chr20	17594380	+	UBXN4	chr2	136541303	-
82441	PRAD	TCGA-HC-7077-01A	RRBP1	chr20	17610468	-	VDAC3	chr8	42257169	+
78296	N/A	AV686345	RRBP1	chr20	17600337	-	XKR3	chr22	17292825	+
101574	OV	TCGA-24-2020	RRBP1	chr20	17660643	-	YWHAE	chr17	1268352	-
101574	OV	TCGA-24-2020	RRBP1	chr20	17660643	-	YWHAE	chr17	1273035	-
101574	OV	TCGA-24-2020	RRBP1	chr20	17662672	-	YWHAE	chr17	1268352	-
101574	OV	TCGA-24-2020-01A	RRBP1	chr20	17660640	-	YWHAE	chr17	1268352	-
101574	OV	TCGA-24-2020-01A	RRBP1	chr20	17660644	-	YWHAE	chr17	1268352	-
101574	OV	TCGA-24-2020-01A	RRBP1	chr20	17660644	-	YWHAE	chr17	1273035	-
101574	OV	TCGA-24-2020-01A	RRBP1	chr20	17662673	-	YWHAE	chr17	1268352	-
85013	STAD	TCGA-HU-A4H5	SAFB	chr19	5623405	+	RRBP1	chr20	17641173	-
85013	STAD	TCGA-D7-8575	SLC24A3	chr20	19496208	+	RRBP1	chr20	17617374	-
85015	STAD	TCGA-KB-A93H	SNX5	chr20	17934639	-	RRBP1	chr20	17641173	-

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Prognostic Analysis

Kaplan-Meier plots with logrank tests of overall survival (OS)

Cancer type

Translation factor

Coefficent

Hazard ratio

Wald test pval

Likelihool ratio pval

Logrank test pval

# samples

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Translation factor and Gender

Differential gene expression between female and male. (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
SARC	RRBP1	0.000226628491007696	0.0061
ACC	RRBP1	0.000264493148098681	0.0069
STAD	RRBP1	0.000799554252485744	0.02
KIRC	RRBP1	0.0392330511030901	0.94
CHOL	RRBP1	0.0462133010566923	1
TGCT	RRBP1	2.38208541342948e-05	0.00067

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Translation factor and Age

Differential gene expression between young and old age groups (Wilcoxon test, pval<0.05)

Cancer type	Translation factor	pval	adj.p
LUSC	RRBP1	0.0141210268920065	0.4
GBM	RRBP1	0.00957184459812268	0.28
LGG	RRBP1	1.35063556891159e-11	4.5e-10
ESCA	RRBP1	0.000165148194859485	0.0053
THYM	RRBP1	0.00266311925913856	0.083
SARC	RRBP1	0.018705057499887	0.51
CHOL	RRBP1	0.048373577638804	1
HNSC	RRBP1	0.00421140472375476	0.13

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Related Drugs

Drugs targeting genes involved in this translation factor.
(DrugBank Version 5.1.8 2021-05-08)

UniProtAcc	DrugBank ID	Drug name	Drug activity	Drug type	Drug status
Q9P2E9	DB12339	Radezolid		Small molecule	Investigational
Q9P2E9	DB12339	Radezolid

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Related Diseases

Diseases associated with this translation factor.
(DisGeNet 4.0)

Disease ID

Disease Name

# PubMeds

Disease source